CN117461694A - Nutritional composition for regulating immunity and metabolism function and treating hyperuricemia and gout - Google Patents

Nutritional composition for regulating immunity and metabolism function and treating hyperuricemia and gout Download PDF

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Publication number
CN117461694A
CN117461694A CN202310950341.4A CN202310950341A CN117461694A CN 117461694 A CN117461694 A CN 117461694A CN 202310950341 A CN202310950341 A CN 202310950341A CN 117461694 A CN117461694 A CN 117461694A
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parts
powder
nutritional composition
gout
hyperuricemia
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李勇
赵伟
祁兴普
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Femjost International Health Management Co ltd
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Femjost International Health Management Co ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/152Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/156Flavoured milk preparations ; Addition of fruits, vegetables, sugars, sugar alcohols or sweeteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/152Milk preparations; Milk powder or milk powder preparations containing additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/152Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1526Amino acids; Peptides; Protein hydrolysates; Nucleic acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/152Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/154Milk preparations; Milk powder or milk powder preparations containing additives containing thickening substances, eggs or cereal preparations; Milk gels
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/16Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/18Milk in dried and compressed or semi-solid form
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/20Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A23C9/206Colostrum; Human milk
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/42Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/44Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/46Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing dairy products
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/48Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The invention discloses a nutritional composition for conditioning immunity and metabolism to treat hyperuricemia and gout, and particularly relates to the technical field of hyperuricemia and gout treatment, wherein the raw materials comprise the following components in parts by weight: 12-26 parts of sorbitol, 8-11 parts of acerola cherry powder, 10-25 parts of bovine coloctrum powder, 5-12 parts of thyme protein peptide, 7-17 parts of chitosan oligosaccharide, 8-25 parts of tuna powder, 7-18 parts of deep sea fish oligopeptide, 6-17 parts of sea cucumber peptide, 7-11 parts of celery seed, 6-10 parts of sunflower disk, 2-8 parts of coix seed powder, 2-10 parts of white gourd powder and 1-8 parts of balsam pear powder. The invention achieves the aim of treating hyperuricemia and gout by regulating the functions of immunity and metabolism.

Description

Nutritional composition for regulating immunity and metabolism function and treating hyperuricemia and gout
Technical Field
The invention relates to the technical field of hyperuricemia and gout treatment, in particular to a nutritional composition for treating hyperuricemia and gout by regulating immunity and metabolic functions.
Background
Hyperuricemia is a metabolic disease caused by purine metabolic disorder and uric acid excretion disorder, and under normal conditions, uric acid in a human body is about 1200mg, about 600mg is newly generated every day, 600mg is excreted at the same time, and the hyperuricemia is in an equilibrium state, but if excessive excretion is not enough in the body or uric acid excretion mechanism is degraded, uric acid in the body is retained too much, and when the uric acid concentration in blood exceeds a normal value, body fluid of the human body becomes acidic, and further urate crystals are formed to deposit on joints to cause gout.
Hyperuricemia is affected by a variety of factors, such as genetics, gender, age, lifestyle, eating habits, etc. With the rapid development of social economy and poor eating and living habits of people, in recent years, the population suffering from hyperuricemia and gout are increasingly growing. Eating the food with high purine, such as animal viscera, seafood food, broth, etc., for a long time, causes the purine components in the body to be increased, and the purine components cannot be excreted from the body in time, further causes the blood uric acid content in the body to be increased, thereby causing high uric acid.
The traditional medicines for promoting kidney to excrete uric acid mainly comprise western medicines of propyl Huang Shu, phenylbromoketone and phenylsulfonyl azolone, and the medicines have larger side effects after long-term administration and are easy to cause damage to liver and kidney. Accordingly, the present invention provides a nutritional composition for treating hyperuricemia and gout by combining the nutritional effects of the nutritional composition.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention provides a nutritional composition for regulating immunity and metabolic function to treat hyperuricemia and gout, and the aim of treating hyperuricemia and gout is achieved through the effects of regulating immunity and metabolic function.
In order to achieve the above purpose, the present invention provides the following technical solutions: the nutritional composition for regulating immunity and metabolism function and treating hyperuricemia and gout comprises the following raw materials in parts by weight: 12-26 parts of sorbitol, 8-11 parts of acerola cherry powder, 10-25 parts of bovine coloctrum powder, 5-12 parts of thyme protein peptide, 7-17 parts of chitosan oligosaccharide, 8-25 parts of tuna powder, 7-18 parts of deep sea fish oligopeptide, 6-17 parts of sea cucumber peptide, 7-11 parts of celery seed, 6-10 parts of sunflower disk, 2-8 parts of coix seed powder, 2-10 parts of white gourd powder and 1-8 parts of balsam pear powder.
Preferably, the raw materials used comprise the following components in parts by weight: 12 parts of sorbitol, 8 parts of acerola powder, 10 parts of bovine coloctrum powder, 5 parts of thyme protein peptide, 7 parts of chitosan oligosaccharide, 8 parts of tuna powder, 7 parts of deep sea fish oligopeptide, 6 parts of sea cucumber peptide, 7 parts of celery seed, 6 parts of sunflower disc, 2 parts of coix seed powder, 2 parts of white gourd powder and 1 part of balsam pear powder.
Preferably, the raw materials used comprise the following components in parts by weight: 20 parts of sorbitol, 9 parts of acerola cherry powder, 18 parts of bovine coloctrum powder, 8 parts of thyme protein peptide, 12 parts of chitosan oligosaccharide, 16 parts of tuna powder, 12 parts of deep sea fish oligopeptide, 11 parts of sea cucumber peptide, 9 parts of celery seed, 8 parts of sunflower disc, 6 parts of coix seed powder, 6 parts of white gourd powder and 5 parts of balsam pear powder.
Preferably, the raw materials used comprise the following components in parts by weight: 26 parts of sorbitol, 11 parts of acerola powder, 25 parts of bovine coloctrum powder, 12 parts of thyme protein peptide, 17 parts of chitosan oligosaccharide, 25 parts of tuna powder, 18 parts of deep sea fish oligopeptide, 17 parts of sea cucumber peptide, 11 parts of celery seed, 10 parts of sunflower disc, 8 parts of coix seed powder, 10 parts of white gourd powder and 8 parts of balsam pear powder.
The invention also includes a method of preparing a nutritional composition for treating hyperuricemia and gout, wherein the nutritional composition is formulated into one of a solid beverage, a tableted sugar, a liquid beverage, an oral liquid, a capsule and a tablet.
Preferably, the method for preparing the nutritional composition into a solid beverage comprises the following steps:
step one: sequentially placing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder into a universal pulverizer for pulverization, and sieving with a 100-120-mesh sieve for later use;
step two: uniformly mixing the powder prepared in the step one in a mixer to obtain mixed powder;
step three: adding edible alcohol into the mixed powder for stirring, and then preparing wet particles by using a particle swinging machine;
step four: placing the wet granules in an oven, drying at 70-88 deg.C for 1-5 hr, sieving with 10-15 mesh sieve, sterilizing, and packaging to obtain the solid beverage.
Preferably, the method for making the nutritional composition into a tabletted candy is specifically:
step one: sequentially placing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder into a universal pulverizer for pulverization, and sieving with a 100-120-mesh sieve for later use;
step two: adding the sieved raw materials into a dry granulating machine for granulating, and then sieving with a 20-25 mesh sieve to obtain a mixture;
step three: adding the mixture and magnesium stearate into a three-dimensional mixer, mixing for 30 minutes, taking out, then placing into a tablet press for tablet pressing and molding, and finally sterilizing and packaging to obtain the nutritional composition tablet candy.
Preferably, the method for preparing the nutritional composition into liquid beverage or oral liquid comprises the following specific steps:
step one: mixing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder with water, and then filtering by using a membrane filter to obtain a blending solution;
step two: sterilizing the mixed solution at 120-130deg.C for 10-30 min, and aseptically packaging to obtain nutritional composition liquid beverage or nutritional composition oral liquid.
Preferably, the method of encapsulating the nutritional composition is specifically:
step one: sequentially placing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder into a universal pulverizer for pulverizing, sieving with 100-120 mesh sieve, and mixing;
step two: and (3) filling the mixture prepared in the step (A) into a soft capsule, shaping, and drying to obtain the nutritional composition capsule.
Preferably, the method of tableting the nutritional composition is specifically:
step one: preparing auxiliary materials, wherein the auxiliary materials comprise 1-3 parts of carboxymethyl cellulose, 2-5 parts of dextrin, 2-5 parts of talcum powder and 1-3 parts of magnesium stearate in parts by weight;
step two: mixing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder, balsam pear powder, carboxymethyl cellulose, dextrin, talcum powder and magnesium stearate, crushing in a crusher, and sieving with a 100-mesh sieve to obtain a mixture;
step three: uniformly mixing the mixture with distilled water until the mixture powder is held by hands to form clusters, wherein the weight of the distilled water is 3-5% of that of the mixture, granulating the mixture by a granulator, and drying at 60-70 ℃ for 10-30 minutes;
step four: tabletting the dried mixture by a tabletting machine, drying at 40-55deg.C for 2-3 hr, and packaging to obtain nutritional composition tablet.
The invention has the technical effects and advantages that:
1. bovine colostrum contains abundant immunoglobulin, and can directly improve immunity of human body; the thymus peptide can promote the differentiation and proliferation of T cells, improve the autoimmune power, and regulate and improve the immune function of tissue cells; the chitosan oligosaccharide contains a large amount of amino acids, and also contains various enzymes and various minerals, so that metabolism in the body can be promoted, and body resistance can be enhanced; the sea cucumber peptide contains bioactive substances such as sea cucumber polysaccharide, sea cucumber saponin and the like, and can improve the immunity of organisms; therefore, the bovine coloctrum powder, the thymus protein peptide, the chitosan oligosaccharide, the deep sea fish oligopeptide and the sea cucumber peptide are added, so that the immunity is improved, and the repair of metabolic damage is promoted;
2. according to the invention, the added tuna powder is used for extracting the anserine in the tuna body, so that uric acid excretion is promoted, and tophus is dissolved;
3. the added celery seeds contain microelements of calcium and phosphorus, are important components for bone development of human bodies, and can promote bone development, increase bone density, prevent osteoporosis and reduce the incidence rate of bone joint diseases;
4. the sunflower discs are added, so that uric acid metabolism in a human body is promoted, and hyperuricemia is relieved;
5. according to the invention, the coix seed powder and the white gourd powder are added to promote metabolism of blood and moisture, so that the Chinese medicinal composition has the effects of promoting urination and detumescence, and is beneficial to promoting uric acid excretion;
6. the balsam pear powder is added, so that the balsam pear has low purine content, is rich in vitamin C, has the effects of resisting inflammation and promoting urination, can reduce uric acid level in blood, can assist in reducing blood sugar, and can prevent hyperuricemia patients from complicating hyperglycemia;
the nutritional composition prepared by the invention achieves the aim of treating hyperuricemia and gout through the functions of regulating immunity and metabolism.
Detailed Description
The following description of the technical solutions in the embodiments of the present invention will be clear and complete, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
The invention provides a nutritional composition for regulating immunity and metabolism function to treat hyperuricemia and gout, which comprises the following raw materials in parts by weight: 12 parts of sorbitol, 8 parts of acerola powder, 10 parts of bovine coloctrum powder, 5 parts of thyme protein peptide, 7 parts of chitosan oligosaccharide, 8 parts of tuna powder, 7 parts of deep sea fish oligopeptide, 6 parts of sea cucumber peptide, 7 parts of celery seed, 6 parts of sunflower disc, 2 parts of coix seed powder, 2 parts of white gourd powder and 1 part of balsam pear powder.
The invention also includes a method of preparing a nutritional composition for treating hyperuricemia and gout, the nutritional composition being made into a solid beverage:
step one: sequentially placing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder into a universal pulverizer for pulverization, and sieving with a 100-mesh sieve for later use;
step two: uniformly mixing the powder prepared in the step one in a mixer to obtain mixed powder;
step three: adding edible alcohol into the mixed powder for stirring, and then preparing wet particles by using a particle swinging machine;
step four: the wet particles are placed in an oven, dried for 1 hour at 70 ℃, then sieved by a 10-mesh sieve, and then sterilized and packaged to obtain the solid drink of the nutritional composition.
The nutritional composition solid beverage prepared in the embodiment is used for seeking 1 male patient with uric acid higher than normal value and gout symptom at the age of 30-70 years, 6g of the nutritional composition solid beverage is dissolved in water for drinking for 30 days for one treatment course every time 2 times, and the daily diet is suitable for light and digestible foods, so that purine-rich foods, fasted spicy greasy foods and tobacco and wine are avoided.
After one treatment course: the blood uric acid before treatment is 590 mu mol/L, the blood uric acid after treatment is 413 mu mol/L, the blood uric acid value is reduced, the symptoms of red swelling, heat pain and the like of the joint disappear, and the joint function is basically recovered.
Example two
The invention provides a nutritional composition for regulating immunity and metabolism function to treat hyperuricemia and gout, which comprises the following raw materials in parts by weight: 20 parts of sorbitol, 9 parts of acerola cherry powder, 18 parts of bovine coloctrum powder, 8 parts of thyme protein peptide, 12 parts of chitosan oligosaccharide, 16 parts of tuna powder, 12 parts of deep sea fish oligopeptide, 11 parts of sea cucumber peptide, 9 parts of celery seed, 8 parts of sunflower disc, 6 parts of coix seed powder, 6 parts of white gourd powder and 5 parts of balsam pear powder.
The invention also includes a method of preparing a nutritional composition for treating hyperuricemia and gout, the nutritional composition being formulated as a tableting candy:
step one: sequentially placing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder into a universal pulverizer for pulverization, and sieving with a 100-mesh sieve for later use;
step two: adding the sieved raw materials into a dry granulating machine for granulating, and then sieving with a 20-mesh sieve to obtain a mixture;
step three: adding the mixture and magnesium stearate into a three-dimensional mixer, mixing for 30 minutes, taking out, then placing into a tablet press for tablet pressing and molding, and finally sterilizing and packaging to obtain the nutritional composition tablet candy.
The nutritional composition prepared by the embodiment is used for tabletting sugar for 1 male patient with uric acid higher than normal value and gout symptom, wherein the male patient is 30-70 years old, 6g of the nutritional composition is taken every time for 30 days as a treatment course, and the daily diet is light and digestible food, so that purine-rich food, fasted spicy greasy food and tobacco wine are avoided.
After one treatment course: the blood uric acid before treatment is 613 mu mol/L, the blood uric acid after treatment is 402 mu mol/L, the blood uric acid value is reduced, the symptoms such as red swelling, heat pain and the like of the joint disappear, and the joint function is basically recovered.
Example III
The invention provides a nutritional composition for regulating immunity and metabolism function to treat hyperuricemia and gout, which comprises the following raw materials in parts by weight: 26 parts of sorbitol, 11 parts of acerola powder, 25 parts of bovine coloctrum powder, 12 parts of thyme protein peptide, 17 parts of chitosan oligosaccharide, 25 parts of tuna powder, 18 parts of deep sea fish oligopeptide, 17 parts of sea cucumber peptide, 11 parts of celery seed, 10 parts of sunflower disc, 8 parts of coix seed powder, 10 parts of white gourd powder and 8 parts of balsam pear powder.
The invention also includes a method of preparing a nutritional composition for treating hyperuricemia and gout, the nutritional composition being made into a liquid beverage:
step one: mixing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder with water, and then filtering by using a membrane filter to obtain a blending solution;
step two: sterilizing the mixed solution at 120 ℃ for 10 minutes, and then carrying out aseptic filling to obtain the nutritional composition liquid beverage.
The liquid drink of the nutritional composition prepared in the embodiment is drunk for 1 male patient with uric acid higher than normal value and gout symptom at the age of 30-70 years, 6g is drunk every time for 30 days as a treatment course, and the daily diet is light and digestible food, so that purine-rich food, fasted spicy greasy food and tobacco and wine are avoided.
After one treatment course: the blood uric acid before treatment is 710 mu mol/L, the blood uric acid after treatment is 390 mu mol/L, the blood uric acid value is obviously reduced, the symptoms such as red swelling, heat pain and the like of the joint disappear, and the joint function is completely recovered.
Example IV
The invention provides a nutritional composition for regulating immunity and metabolism function to treat hyperuricemia and gout, which comprises the following raw materials in parts by weight: 12 parts of sorbitol, 8 parts of acerola powder, 10 parts of bovine coloctrum powder, 5 parts of thyme protein peptide, 7 parts of chitosan oligosaccharide, 8 parts of tuna powder, 7 parts of deep sea fish oligopeptide, 6 parts of sea cucumber peptide, 7 parts of celery seed, 6 parts of sunflower disc, 2 parts of coix seed powder, 2 parts of white gourd powder and 1 part of balsam pear powder.
The invention also comprises a method for preparing the nutritional composition for treating hyperuricemia and gout, wherein the nutritional composition is prepared into oral liquid:
step one: mixing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder with water, and then filtering by using a membrane filter to obtain a blending solution;
step two: sterilizing the mixed solution at 120 ℃ for 10 minutes, and then carrying out aseptic filling to obtain the nutritional composition oral liquid.
The nutritional composition oral liquid prepared in the embodiment is drunk for 1 female patient with uric acid higher than normal value and gout symptom at the age of 30-70 years, 6g is drunk for 30 days each time for one treatment course, and the daily diet is suitable for light and digestible foods, so that purine-rich foods, fasted spicy greasy foods and tobacco and wine are avoided.
After one treatment course: the blood uric acid before treatment is 524 mu mol/L, the blood uric acid after treatment is 350 mu mol/L, the blood uric acid value is reduced, the symptoms such as red swelling, heat pain and the like of the joint disappear, and the joint function is basically recovered.
Example five
The invention provides a nutritional composition for regulating immunity and metabolism function to treat hyperuricemia and gout, which comprises the following raw materials in parts by weight: the raw materials used in the method comprise the following components in parts by weight: 20 parts of sorbitol, 9 parts of acerola cherry powder, 18 parts of bovine coloctrum powder, 8 parts of thyme protein peptide, 12 parts of chitosan oligosaccharide, 16 parts of tuna powder, 12 parts of deep sea fish oligopeptide, 11 parts of sea cucumber peptide, 9 parts of celery seed, 8 parts of sunflower disc, 6 parts of coix seed powder, 6 parts of white gourd powder and 5 parts of balsam pear powder.
The invention also includes a method of preparing a nutritional composition for treating hyperuricemia and gout, encapsulating the nutritional composition:
step one: sequentially placing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder into a universal pulverizer for pulverizing, sieving with a 100-mesh sieve, and mixing;
step two: and (3) filling the mixture prepared in the step (A) into a soft capsule, shaping, and drying to obtain the nutritional composition capsule.
The nutritional composition capsule prepared in the embodiment is taken for 1 female patient with uric acid higher than normal value and gout symptom, 2 times a day, 6g each time for 30 days as a treatment course, and the daily diet is suitable for light and digestible food, so that purine-rich food, fasted spicy and greasy food and tobacco wine are avoided.
After one treatment course: the blood uric acid before treatment is 635 mu mol/L, the blood uric acid after treatment is 344 mu mol/L, the blood uric acid value is reduced, the symptoms such as red swelling, heat pain and the like of the joint disappear, and the joint function is basically recovered.
Example six
The invention provides a nutritional composition for regulating immunity and metabolism function to treat hyperuricemia and gout, which comprises the following raw materials in parts by weight: the raw materials used in the method comprise the following components in parts by weight: 26 parts of sorbitol, 11 parts of acerola powder, 25 parts of bovine coloctrum powder, 12 parts of thyme protein peptide, 17 parts of chitosan oligosaccharide, 25 parts of tuna powder, 18 parts of deep sea fish oligopeptide, 17 parts of sea cucumber peptide, 11 parts of celery seed, 10 parts of sunflower disc, 8 parts of coix seed powder, 10 parts of white gourd powder and 8 parts of balsam pear powder.
The invention also includes a method of preparing a nutritional composition for treating hyperuricemia and gout, the nutritional composition being formulated into a tablet:
step one: preparing auxiliary materials, wherein the auxiliary materials comprise 2 parts of carboxymethyl cellulose, 3 parts of dextrin, 3 parts of talcum powder and 2 parts of magnesium stearate in parts by weight;
step two: mixing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder, balsam pear powder, carboxymethyl cellulose, dextrin, talcum powder and magnesium stearate, crushing in a crusher, and sieving with a 100-mesh sieve to obtain a mixture;
step three: uniformly mixing the mixture with distilled water until the mixture powder is held by hands to form clusters, wherein the weight of the distilled water is 5% of that of the mixture, granulating the mixture by a granulator, and drying at 70 ℃ for 30 minutes;
step four: tabletting the dried mixture by a tabletting machine, drying at 55 ℃ for 3 hours, entering a conventional coating procedure after drying, and finally packaging to obtain the nutritional composition tablet.
The nutritional composition tablet prepared in the embodiment is taken for 1 female patient with uric acid higher than normal value and gout symptom, which is 30-70 years old, 2 times per day, 6g per day for 30 days as a treatment course, and the daily diet is light and digestible food, so that purine-rich food, fasted spicy greasy food and tobacco wine are avoided.
After one treatment course: before treatment, the blood uric acid is 676 mu mol/L, after treatment, the blood uric acid is 321 mu mol/L, the blood uric acid value is obviously reduced, the symptoms such as red swelling, heat pain and the like of the joint are completely disappeared, and the joint function is completely recovered.
According to examples one to six, the following data were obtained:
from this, it can be seen that the nutritional composition prepared by the present invention has the purpose of treating hyperuricemia and gout.
Finally: the foregoing description of the preferred embodiments of the invention is not intended to limit the invention to the precise form disclosed, and any such modifications, equivalents, and alternatives falling within the spirit and principles of the invention are intended to be included within the scope of the invention.

Claims (10)

1. A nutritional composition for conditioning immunity and metabolism to treat hyperuricemia and gout, characterized in that: the raw materials used comprise the following components in parts by weight: 12-26 parts of sorbitol, 8-11 parts of acerola cherry powder, 10-25 parts of bovine coloctrum powder, 5-12 parts of thyme protein peptide, 7-17 parts of chitosan oligosaccharide, 8-25 parts of tuna powder, 7-18 parts of deep sea fish oligopeptide, 6-17 parts of sea cucumber peptide, 7-11 parts of celery seed, 6-10 parts of sunflower disk, 2-8 parts of coix seed powder, 2-10 parts of white gourd powder and 1-8 parts of balsam pear powder.
2. The nutritional composition for conditioning immunity and metabolic function for the treatment of hyperuricemia and gout according to claim 1, wherein: the raw materials used in the method comprise the following components in parts by weight: 12 parts of sorbitol, 8 parts of acerola powder, 10 parts of bovine coloctrum powder, 5 parts of thyme protein peptide, 7 parts of chitosan oligosaccharide, 8 parts of tuna powder, 7 parts of deep sea fish oligopeptide, 6 parts of sea cucumber peptide, 7 parts of celery seed, 6 parts of sunflower disc, 2 parts of coix seed powder, 2 parts of white gourd powder and 1 part of balsam pear powder.
3. The nutritional composition for conditioning immunity and metabolic function for the treatment of hyperuricemia and gout according to claim 1, wherein: the raw materials used in the method comprise the following components in parts by weight: 20 parts of sorbitol, 9 parts of acerola cherry powder, 18 parts of bovine coloctrum powder, 8 parts of thyme protein peptide, 12 parts of chitosan oligosaccharide, 16 parts of tuna powder, 12 parts of deep sea fish oligopeptide, 11 parts of sea cucumber peptide, 9 parts of celery seed, 8 parts of sunflower disc, 6 parts of coix seed powder, 6 parts of white gourd powder and 5 parts of balsam pear powder.
4. The nutritional composition for conditioning immunity and metabolic function for the treatment of hyperuricemia and gout according to claim 1, wherein: the raw materials used in the method comprise the following components in parts by weight: 26 parts of sorbitol, 11 parts of acerola powder, 25 parts of bovine coloctrum powder, 12 parts of thyme protein peptide, 17 parts of chitosan oligosaccharide, 25 parts of tuna powder, 18 parts of deep sea fish oligopeptide, 17 parts of sea cucumber peptide, 11 parts of celery seed, 10 parts of sunflower disc, 8 parts of coix seed powder, 10 parts of white gourd powder and 8 parts of balsam pear powder.
5. A method of preparing a nutritional composition for conditioning immunity and metabolic function according to any one of claims 1-4 for the treatment of hyperuricemia and gout, characterized in that: the nutritional composition is formulated into one of solid beverage, tabletted candy, liquid beverage, oral liquid, capsule and tablet.
6. The method for preparing the nutritional composition for regulating immunity and metabolic function for treating hyperuricemia and gout according to claim 5, wherein the method comprises the following steps: the method for preparing the nutritional composition into the solid beverage comprises the following steps:
step one: sequentially placing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder into a universal pulverizer for pulverization, and sieving with a 100-120-mesh sieve for later use;
step two: uniformly mixing the powder prepared in the step one in a mixer to obtain mixed powder;
step three: adding edible alcohol into the mixed powder for stirring, and then preparing wet particles by using a particle swinging machine;
step four: placing the wet granules in an oven, drying at 70-88 deg.C for 1-5 hr, sieving with 10-15 mesh sieve, sterilizing, and packaging to obtain the solid beverage.
7. The method for preparing the nutritional composition for regulating immunity and metabolic function for treating hyperuricemia and gout according to claim 5, wherein the method comprises the following steps: the method for preparing the nutritional composition into the pressed candy comprises the following steps:
step one: sequentially placing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder into a universal pulverizer for pulverization, and sieving with a 100-120-mesh sieve for later use;
step two: adding the sieved raw materials into a dry granulating machine for granulating, and then sieving with a 20-25 mesh sieve to obtain a mixture;
step three: adding the mixture and magnesium stearate into a three-dimensional mixer, mixing for 30 minutes, taking out, then placing into a tablet press for tablet pressing and molding, and finally sterilizing and packaging to obtain the nutritional composition tablet candy.
8. The method for preparing the nutritional composition for regulating immunity and metabolic function for treating hyperuricemia and gout according to claim 5, wherein the method comprises the following steps: the method for preparing the nutritional composition into liquid beverage or oral liquid comprises the following steps:
step one: mixing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder with water, and then filtering by using a membrane filter to obtain a blending solution;
step two: sterilizing the mixed solution at 120-130deg.C for 10-30 min, and aseptically packaging to obtain nutritional composition liquid beverage or nutritional composition oral liquid.
9. The method for preparing the nutritional composition for regulating immunity and metabolic function for treating hyperuricemia and gout according to claim 5, wherein the method comprises the following steps: the method for making the nutritional composition into the capsule comprises the following steps:
step one: sequentially placing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder and balsam pear powder into a universal pulverizer for pulverizing, sieving with 100-120 mesh sieve, and mixing;
step two: and (3) filling the mixture prepared in the step (A) into a soft capsule, shaping, and drying to obtain the nutritional composition capsule.
10. The method for preparing the nutritional composition for regulating immunity and metabolic function for treating hyperuricemia and gout according to claim 5, wherein the method comprises the following steps: the method for preparing the nutritional composition into the tablet comprises the following steps:
step one: preparing auxiliary materials, wherein the auxiliary materials comprise 1-3 parts of carboxymethyl cellulose, 2-5 parts of dextrin, 2-5 parts of talcum powder and 1-3 parts of magnesium stearate in parts by weight;
step two: mixing sorbitol, acerola cherry powder, bovine coloctrum powder, thyme protein peptide, chitosan oligosaccharide, tuna powder, deep sea fish oligopeptide, sea cucumber peptide, celery seed, sunflower disc, pearl barley powder, white gourd powder, balsam pear powder, carboxymethyl cellulose, dextrin, talcum powder and magnesium stearate, crushing in a crusher, and sieving with a 100-mesh sieve to obtain a mixture;
step three: uniformly mixing the mixture with distilled water until the mixture powder is held by hands to form clusters, wherein the weight of the distilled water is 3-5% of that of the mixture, granulating the mixture by a granulator, and drying at 60-70 ℃ for 10-30 minutes;
step four: tabletting the dried mixture by a tabletting machine, drying at 40-55deg.C for 2-3 hr, and packaging to obtain nutritional composition tablet.
CN202310950341.4A 2023-07-31 2023-07-31 Nutritional composition for regulating immunity and metabolism function and treating hyperuricemia and gout Pending CN117461694A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117882774A (en) * 2024-03-13 2024-04-16 中国农业大学 Composition with uric acid reducing effect and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117882774A (en) * 2024-03-13 2024-04-16 中国农业大学 Composition with uric acid reducing effect and application thereof

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