CN117379315A - Automatic preparation system of radioactive capsule - Google Patents

Automatic preparation system of radioactive capsule Download PDF

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Publication number
CN117379315A
CN117379315A CN202311707445.9A CN202311707445A CN117379315A CN 117379315 A CN117379315 A CN 117379315A CN 202311707445 A CN202311707445 A CN 202311707445A CN 117379315 A CN117379315 A CN 117379315A
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CN
China
Prior art keywords
capsule
radioactive
hole
preparation system
empty
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202311707445.9A
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Chinese (zh)
Inventor
张雪峰
毛宝丰
付博
马红利
郭宏利
孙寿涛
孙锐锋
魏守峰
郗健伟
周光伟
穆晗
巍凯
刘中瑞
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Atom High Tech Co ltd
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Atom High Tech Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Atom High Tech Co ltd filed Critical Atom High Tech Co ltd
Priority to CN202311707445.9A priority Critical patent/CN117379315A/en
Publication of CN117379315A publication Critical patent/CN117379315A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G47/00Article or material-handling devices associated with conveyors; Methods employing such devices
    • B65G47/74Feeding, transfer, or discharging devices of particular kinds or types
    • B65G47/80Turntables carrying articles or materials to be transferred, e.g. combined with ploughs or scrapers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074Filling capsules; Related operations

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The invention relates to the technical field of capsule preparation, and provides an automatic preparation system of a radioactive capsule, which comprises the following steps: the device comprises a rotating device, a discharging device, a separating device, a filling device, a liquid medicine dripping device and a bag closing device, wherein the rotating device comprises a material disc and a plurality of push rods, a plurality of material holes are annularly formed in the material disc, one end of each push rod is provided with a containing hole, and when the push rods stretch out and draw back, the containing holes can be aligned with or staggered from the material holes; the blanking device is used for conveying the empty capsule shells into the accommodating holes and the material holes; the separating device is used for separating the empty capsule shells; the filling device is used for filling the capsule powder into the capsule body; the medicine dripping device is used for dripping the radioactive medicine liquid into the capsule body; the capsule closing device is used for sleeving the capsule cap and the capsule body. The automatic preparation system realizes full-automatic preparation of the radioactive capsules, has high production efficiency and high qualification rate of the reflective capsules, and simultaneously reduces the radiation to operators in the production process.

Description

Automatic preparation system of radioactive capsule
Technical Field
The invention relates to the technical field of capsule preparation, in particular to an automatic preparation system of a radioactive capsule.
Background
The radioactive sodium iodide diagnostic capsule is a radioactive drug for diagnosing hyperthyroidism at present, and is a preferable drug for diagnosing hyperthyroidism because of simple use and small radioactive pollution when the drug is taken by patients.
The existing device for preparing the radioactive sodium iodide diagnostic capsules is semi-automatic equipment, and can only automatically drip radioactive liquid medicine into the powder filled capsules, but cannot perform operations such as capsule body separation, capsule closing and the like. The operations such as separation and closing of the capsule body cannot be operated due to the limitation of the operation of the manipulator in the radioactive hot chamber, so that an operator is required to manually operate the radioactive sodium iodide diagnostic capsule with a large production quantity, the total preparation time of the radioactive sodium iodide diagnostic capsule is too long, and the hand radiation dose of the operator is high. Based on the above, an automatic preparation system of the radioactive capsule is provided, so that the preparation time of the radioactive capsule is shortened, and meanwhile, the problem that radioactive elements cause injury to operators is urgently solved in the industry.
Disclosure of Invention
The invention provides an automatic preparation system of a radioactive capsule, which is used for solving the defects that in the prior art, the preparation time of the radioactive capsule is longer and the radiation dose of the hands of operators is higher.
The invention provides an automatic preparation system of a radioactive capsule, which comprises the following components: the rotating device comprises a material disc and a plurality of push rods, wherein a plurality of material holes are annularly formed in the material disc, each material hole is correspondingly provided with one push rod, one end of each push rod is provided with a containing hole, and when the push rods stretch out and draw back, the containing holes can be aligned with or staggered from the material holes; the blanking device is used for conveying empty capsule shells into the accommodating holes and the material holes; the separation device is arranged below the material tray and is used for separating the empty capsule shells so as to enable the capsule bodies to be contained in the material holes, and the capsule caps to be contained in the containing holes; filling means for filling capsule powder into the capsule body; a medicine dripping device for dripping the radioactive medicine liquid into the capsule body; the capsule closing device is used for sleeving the capsule cap and the capsule body; the material tray is rotatable, so that the material hole is driven to sequentially move to the blanking device, the filling device, the liquid medicine dripping device and the bag closing device, when the material hole is positioned at the blanking device and the bag closing device, the material hole is aligned with the containing hole, and when the material hole is positioned at the filling device and the liquid medicine dripping device, the material hole is staggered with the containing hole.
According to the automatic preparation system of the radioactive capsule provided by the invention, the blanking device comprises: a first bracket; the first hopper is arranged on the first bracket and is used for blanking the empty capsule shells; the driving mechanism is arranged on the first bracket and is used for pushing part of the capsule body into the accommodating hole; and the material pressing mechanism is used for pressing the empty capsule shell into the containing hole and the material hole.
According to the invention, there is provided an automated preparation system for a radioactive capsule, the drive mechanism comprising: the first driving piece is arranged on the first bracket and can stretch out and draw back; the guide block is connected with the first driving piece and is used for guiding the empty capsule shell so that the part of the capsule body can vertically fall into the accommodating hole under the pushing of the first driving piece.
According to the present invention there is provided an automated preparation system for a radioactive capsule, the separation device comprising: the second driving piece is arranged below the material disc; the first sucker is connected with the second driving piece, and the second driving piece is used for driving the first sucker to move towards the direction close to the capsule body so as to be attracted with the capsule body; the second driving piece is also used for driving the first sucker to move in a direction away from the capsule cap after the first sucker is sucked with the capsule body so as to separate the capsule body from the capsule cap.
The automatic preparation system of the radioactive capsule provided by the invention further comprises a rejecting device, wherein the rejecting device is used for rejecting empty capsule shells which are not separated, and the rejecting device comprises: the photoelectric sensors are arranged above the material tray and are respectively used for detecting the capsule caps and the capsule bodies; the ejection mechanism is arranged below the material disc and is used for ejecting the empty capsule shells which are not separated; and the suction pipe is arranged above the material tray and is used for cooperating with the ejection mechanism to eject the empty capsule shells which are not separated out of the accommodating holes.
According to the present invention there is provided an automated preparation system for a radioactive capsule, said filling device comprising: a second bracket; the second hopper is arranged on the second bracket, and capsule powder is arranged in the second hopper; the first motor is arranged above the second hopper; the screw rod is connected with the first motor, one end of the screw rod penetrates through the second funnel and can extend into the capsule body, and the first motor is used for driving the screw rod to rotate so as to leak the capsule powder into the capsule body.
According to the automatic preparation system of the radioactive capsule provided by the invention, the liquid medicine dripping device comprises: a medicine liquid bottle containing the radioactive medicine liquid; and the injection needle is connected with the liquid medicine bottle and is used for injecting the radioactive liquid medicine into the capsule body filled with the capsule powder.
According to the invention, the automatic preparation system of the radioactive capsule provided by the invention comprises: the cover plate is arranged on the push rod and can move to the position above the accommodating hole; the third driving piece is arranged below the material disc; the first thimble is connected with the third driving piece, and under the drive of the third driving piece, the first thimble can stretch into in the material hole, promotes the capsule body to overlap with the capsule cap.
The automatic preparation system of the radioactive capsule provided by the invention further comprises a detection device, wherein the detection device comprises: a sliding mechanism; the second motor is connected with the sliding mechanism, and the sliding mechanism can drive the second motor to move transversely and longitudinally; the second sucker is connected with the second motor and is used for sucking the sleeved capsules; and the detection mechanism is used for detecting the appearance quality of the capsule.
According to the invention, the automatic preparation system of the radioactive capsule provided by the invention, the detection mechanism comprises: a visual camera for photographing the appearance of the capsule; the light source is arranged on the sliding mechanism and used for providing illumination for the vision camera; and the background plate is arranged opposite to the vision camera.
According to the automatic preparation system of the radioactive capsule, provided by the invention, the automatic conveying and separating of empty capsule shells, the filling of capsule powder by a capsule body, the dripping of the radioactive liquid medicine and the automatic capsule closing are realized by arranging the rotating device, the blanking device, the separating device, the filling device, the liquid medicine dripping device and the capsule closing device, the full-automatic preparation of the radioactive capsule is realized, the production efficiency is high, the qualification rate of the reflective capsule is high, and meanwhile, the radiation to an operator in the production process is reduced.
Drawings
In order to more clearly illustrate the invention or the technical solutions of the prior art, the following description will briefly explain the drawings used in the embodiments or the description of the prior art, and it is obvious that the drawings in the following description are some embodiments of the invention, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of an automated preparation system for a radioactive capsule provided by the present invention;
fig. 2 is a schematic structural view of the rotating device shown in fig. 1;
fig. 3 is a schematic structural view of the discharging device shown in fig. 1;
FIG. 4 is a schematic view of the rejecting device shown in FIG. 1;
fig. 5 is a schematic structural view of the filling device, the liquid medicine dripping device, and the bag closing device shown in fig. 1;
fig. 6 is a schematic structural view of the detecting device shown in fig. 1;
reference numerals:
10: a blanking device; 11: a first bracket; 12: a first funnel; 13: a delivery tube; 14: a first driving member; 15: a guide block; 16: a fourth driving member; 17: a second thimble; 20: a rejecting device; 21: a photoelectric sensor; 22: a fifth driving member; 23: a third thimble; 24: a suction pipe; 25: a housing case; 30: a filling device; 31: a second bracket; 32: a second funnel; 33: a first motor; 34: a screw; 35: a sixth driving member; 36: a partition plate; 40: a drug drip device; 41: a liquid medicine bottle; 42: a pump; 43: an injection needle; 44: a third bracket; 45: a seventh driving member; 46: clamping blocks; 47: cleaning the bottle; 50: a bag closing device; 51: a third driving member; 52: a first thimble; 53: a cover plate; 60: a detection device; 61: a first sliding table; 62: a second sliding table; 63: a second motor; 64: a second suction cup; 65: a vision camera; 66: a light source; 67: a background plate; 71: a second driving member; 72: a first suction cup; 100: a rotating device; 101: a material tray; 102: a push rod; 103: a receiving block; 104: a third motor; 200: a control cabinet; 300: a display screen; 401: a capsule body; 402: a capsule cap; 1011: a material hole; 1031: and a receiving hole.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings, and it is apparent that the described embodiments are some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The features of the invention "first", "second" and the like in the description and in the claims may be used for the explicit or implicit inclusion of one or more such features. In the description of the present invention, unless otherwise indicated, the meaning of "a plurality" is two or more.
An automated preparation system for a radioactive capsule of the present invention is described below in connection with fig. 1-6.
As shown in fig. 1, in an embodiment of the present invention, an automated preparation system for a radioactive capsule includes: the device comprises a rotating device 100, a blanking device 10, a separating device, a filling device 30, a liquid medicine dripping device 40 and a bag closing device 50. The rotating device 100 comprises a material disc 101 and push rods 102, wherein a plurality of material holes 1011 are annularly formed in the material disc 101, one push rod 102 is correspondingly arranged in each material hole 1011, one end of each push rod 102 is provided with a containing block 103, each containing block 103 is provided with a containing hole 1031, and the push rods 102 can drive the containing blocks 103 to move so that each containing hole 1031 is aligned with or staggered with one material hole 1011 respectively. The blanking device 10 is used for conveying empty capsule shells into the containing hole 1031 and the material hole 1011, the separating device is arranged below the material disc 101, and the separating device is used for separating the empty capsule shells, so that the capsule body 401 is contained in the material hole 1011, and the capsule cap 402 is contained in the containing hole 1031. The filling device 30 is used for filling capsule powder into the capsule body 401, the liquid medicine dripping device 40 is used for dripping radioactive liquid medicine into the capsule body 401, the capsule closing device 50 is used for sleeving the capsule cap 402 and the capsule body 401, wherein the material disc 101 can rotate to drive the material hole 1011 to sequentially move to the blanking device 10, the filling device 30, the liquid medicine dripping device 40 and the capsule closing device 50, when the material hole 1011 is positioned at the blanking device 10 and the capsule closing device 50, the material hole 1011 is aligned with the accommodating hole 1031, and when the material hole 1011 is positioned at the filling device 30 and the liquid medicine dripping device 40, the material hole 1011 is staggered with the accommodating hole 1031.
Specifically, as shown in fig. 2, the rotating apparatus 100 includes: a tray 101, a plurality of pushers 102 and a third motor 104. The third motor 104 is used for driving the material disc 101 to rotate, the material disc 101 is annularly provided with a plurality of material holes 1011 along the circumferential direction thereof, each material hole 1011 is correspondingly provided with a push rod 102, one end of each push rod 102 is provided with a containing block 103, the containing block 103 is provided with a containing hole 1031, and the containing hole 1031 and the material hole 1011 are through holes. A rotary pneumatic connector is arranged in the center of the material disc 101 and provides power for the extension and contraction of the push rod 102, and the push rod 102 can drive the accommodating block 103 to move when in extension and contraction so as to align or stagger the accommodating hole 1031 with the material hole 1011. Alternatively, in an embodiment of the present invention, the third motor 104 is a rotary servo motor.
In actual operation, first, the third motor 104 rotates to rotate any material hole 1011 to the station where the blanking device 10 is located, the push rod 102 drives the accommodating block 103 to move, so that the accommodating hole 1031 is aligned with the material hole 1011, the blanking device 10 blanks the empty capsule shell into the accommodating hole 1031 and the material hole 1011, and at this time, the capsule body 401 and the capsule cap 402 are in a sleeved state. In this embodiment, the separating device and the blanking device 10 are at the same station, the separating device is located below the material tray 101, a part of the separating device extends into the material hole 1011 to be attracted with the capsule body 401, then the part moves in a direction away from the capsule cap 402, and further the capsule body 401 is separated from the capsule cap 402, after separation, the capsule body 401 is located in the material hole 1011, and the capsule cap 402 is located in the containing hole 1031.
The third motor 104 drives the material disc 101 to rotate to the station where the filling device 30 is located, and the push rod 102 contracts, so that the capsule cap 402 and the capsule body 401 are staggered. The capsule body 401 is aligned with the filling device 30 and capsule powder is fed into the capsule body 401 by the filling device 30.
The third motor 104 drives the material tray 101 to continue to rotate to the station where the liquid medicine dripping device 40 is located, and the liquid medicine dripping device 40 drips the radioactive liquid medicine into the capsule body 401. Then, the third motor 104 drives the material tray 101 to rotate to the station where the capsule closing device 50 is located, and the push rod 102 drives the accommodating block 103 to move, so that the accommodating hole 1031 is aligned with the material hole 1011 again, that is, the capsule cap 402 is aligned with the capsule body 401 filled with the capsule powder and the radioactive liquid medicine. The capsule closing device 50 pushes the capsule body 401 upward, thereby allowing the capsule body 401 to be sleeved with the capsule cap 402.
According to the automatic preparation system of the radioactive capsule, provided by the embodiment of the invention, the automatic conveying and separating of empty capsule shells, the filling of capsule powder in a capsule body, the dripping of the radioactive liquid medicine and the automatic capsule closing are realized by arranging the rotating device, the blanking device, the separating device, the filling device, the liquid medicine dripping device and the capsule closing device, the full-automatic preparation of the radioactive capsule is realized, the production efficiency is high, the qualification rate of the reflective capsule is high, and meanwhile, the radiation to operators in the production process is reduced.
Further, in the embodiment of the present invention, the automated preparation system of the radioactive capsule has 6 preparation stations in total, and each station is described in detail in the following sequence of stations.
As shown in fig. 3, the blanking device 10 includes: the capsule shell conveying device comprises a first bracket 11, a first funnel 12, a driving mechanism and a pressing mechanism, wherein the first funnel 12 is arranged on the first bracket 11, and the first funnel 12 is used for conveying empty capsule shells. The driving mechanism is arranged on the first bracket 11, the driving mechanism is used for pushing part of the capsule body 401 into the accommodating hole 1031, and the material pressing mechanism is used for pressing the empty capsule shell into the accommodating hole 1031 and the material hole 1011.
Specifically, the blanking station is the first station of the automatic preparation system, and the blanking station is provided with a blanking device 10. The first funnel 12 is connected with a conveying pipe 13, an empty capsule shell is accommodated in the first funnel 12, the empty capsule shell is conveyed onto a connecting plate of the first bracket 11 by the first funnel 12 and the conveying pipe 13 and is abutted with a driving mechanism, the driving mechanism pushes the empty capsule shell to move onto the accommodating block 103, a part of the capsule body 401 automatically falls into the accommodating hole 1031, and the pressing mechanism moves downwards to press the empty capsule shell into the accommodating hole 1031 and the material hole 1011.
Further, in an embodiment of the present invention, the driving mechanism includes: a first driving member 14 and a guide block 15. The first driving piece 14 is arranged on the first bracket 11, the first driving piece 14 is telescopic, the guide block 15 is connected with the first driving piece 14, and the guide block 15 is used for guiding the empty capsule shell so that the part of the capsule body 401 can vertically fall into the accommodating hole 1031 under the pushing of the first driving piece 14. The swager constructs including: the fourth driving piece 16 and the second thimble 17, the fourth driving piece 16 is used for driving the second thimble 17 to move, and the second thimble 17 is used for pressing the empty capsule shell into the accommodating hole 1031 and the material hole 1011.
Specifically, in this embodiment, the accommodating hole 1031 is aligned with the material hole 1011, the empty capsule shells can be fed by the first hopper 12 and the conveying pipe 13 one by one, the empty capsule shells fall onto the connecting plate of the first bracket 11 after being conveyed out by the conveying pipe 13, the side surfaces of the empty capsule shells are abutted with the guide blocks 15, and the guide blocks 15 are used for guiding the empty capsule shells, so that the empty capsule shells are perpendicular to the connecting plate. The first driving member 14 pushes the guide block 15 to move, so that the empty capsule shell is pushed onto the accommodating block 103, and then a part of the empty capsule shell falls into the accommodating hole 1031. The fourth driving piece 16 drives the second ejector pin 17 to move downwards, the second ejector pin 17 is abutted with the empty capsule body, and all the empty capsule body is pushed to enter the containing hole 1031 and the material hole 1011.
Further, the blanking device 10 is a first station of an automatic preparation system, where not only blanking of empty capsule shells but also separation of empty capsule shells are to be achieved. The separation device comprises: a second driving member 71 and a first suction cup 72. The second driving piece 71 is arranged below the material disc 101, the first sucker 72 is connected with the second driving piece 71, and the second driving piece 71 is used for driving the first sucker 72 to move towards the direction close to the capsule body 401 so as to be attracted with the capsule body 401; the second driving member 71 is further configured to drive the first suction cup 72 to move away from the capsule cap 402 after the first suction cup 72 is engaged with the capsule body 401, so as to separate the capsule body 401 from the capsule cap 402.
Specifically, after the empty capsule shell is located in the accommodating hole 1031 and the material hole 1011, the second driving member 71 drives the first suction disc 72 to move upwards, after the first suction disc 72 abuts against the capsule body 401, the first suction disc 72 is attracted to the capsule body 401, and the second driving member 71 drives the first suction disc 72 to move downwards, so that the capsule body 401 is separated from the capsule cap 402, after separation, the capsule body 401 is located in the material hole 1011, and the capsule cap 402 is located in the accommodating hole 1031. Then, the push rod 102 is contracted, and the accommodating block 103 is driven away from the material hole 1011, so that the capsule cap 402 is separated from the capsule body 401.
As shown in fig. 4, the second station of the automated preparation system is a rejecting station, and the rejecting station is provided with a rejecting device 20, and the rejecting device 20 is used for rejecting empty capsule shells which are not separated. The rejecting device 20 includes: a plurality of photoelectric sensors 21, an ejection mechanism, and a suction tube 24. The plurality of photoelectric sensors 21 are disposed above the tray 101, and the plurality of photoelectric sensors 21 are respectively used for detecting the capsule body 401 and the capsule cap 402. The ejection mechanism is arranged below the material tray 101 and is used for ejecting the empty capsule shells which are not separated. The suction tube 24 is disposed above the tray 101, and the suction tube 24 is used for cooperating with an ejection mechanism to eject the empty capsule shell that is not separated out of the receiving hole 1031.
Specifically, in the process of separating the capsule body 401 from the capsule cap 402 by the separating device, since the capsule cap 402 has no fixing device, when the second driving member 71 moves downward, the empty capsule shell may be driven to move downward as a whole for partially covering the empty capsule body, so that the empty capsule shell cannot be separated. Two photoelectric sensors 21 are arranged above the material tray 101, and when one of the two photoelectric sensors 21 detects the capsule cap 402 and the other detects the capsule body 401, the capsule body 401 is separated from the capsule cap 402; when one of the photosensors 21 detects the capsule cap 402 and the other photosensor 21 does not detect the capsule body 401, it is indicated that the capsule body 401 and the capsule cap 402 are not separated. When the capsule body 401 and the capsule cap 402 are not separated, the ejection mechanism cooperates with the suction pipe 24 to eject the empty capsule shell from the material hole 1011 and the receiving hole 1031.
Further, in the present embodiment, the ejection mechanism includes: the fifth driving piece 22 and the third thimble 23, the fifth driving piece 22 and the third thimble 23 are positioned below the material disc 101, the fifth driving piece 22 drives the third thimble 23 to move upwards, the third thimble 23 stretches into the material hole 1011 to push the capsule body 401 upwards, the suction pipe 24 sucks the empty capsule shell by suction force, and the empty capsule shell is pushed out of the accommodating hole 1031 under the combined action of the fifth driving piece 22 and the third thimble 23. Further, the suction tube 24 is connected with a containing box 25, and the sucked empty capsule shells enter the containing box 25 for storage.
The third station of the automated preparation system is a filling station provided with a filling device 30, as shown in fig. 5, the filling device 30 comprising: a second bracket 31, a second hopper 32, a first motor 33 and a screw 34. The second funnel 32 is located the second support 31, is equipped with the capsule powder in the second funnel 32, and the top of second funnel 32 is located to first motor 33, and first motor 33 is connected with screw rod 34, and the one end of screw rod 34 runs through second funnel 32 and can extend to in the capsule body 401, and first motor 33 is used for driving screw rod 34 and rotates to stir the capsule powder, and then makes the capsule powder spill to in the capsule body 401.
Specifically, after the empty capsule shells are separated, the push rod 102 is contracted to drive the capsule cap 402 to leave the material hole 1011, the material disc 101 rotates to the third station, the material hole 1011 is aligned with the discharge hole of the second funnel 32, the second funnel 32 is filled with capsule powder, the first motor 33 rotates to drive the screw 34 to rotate, the screw 34 penetrates through the discharge hole of the second funnel 32 to extend into the capsule body 401, and the screw 34 agitates the capsule powder, so that the capsule powder leaks from the second funnel 32 into the capsule body 401.
Further, in the embodiment of the present invention, the filling device 30 further includes: a sixth driving member 35 and a partition plate 36. The sixth driving piece 35 is connected with the second bracket 31, the sixth driving piece 35 is used for driving the partition plate 36 to move, the partition plate 36 is positioned above the material disc 101, when the capsule body 401 is filled with the capsule powder in proper quantity, the sixth driving piece 35 drives the partition plate 36 to move, and the partition plate 36 seals the discharge hole of the second funnel 32 so as to prevent the capsule powder in the second funnel 32 from leaking.
After the capsule body 401 is filled with the capsule powder, the material disc 101 rotates to a fourth station, the fourth station is a liquid medicine dripping station, and the fourth station is provided with a liquid medicine dripping device 40. The medicine liquid adding device 40 includes: a medicine liquid bottle 41 and an injection needle 43. The medicine bottle 41 contains a radioactive medicine, and the injection needle 43 is connected to the medicine bottle 41, and the injection needle 43 is used to inject the radioactive medicine into the capsule 401 filled with the capsule powder.
Specifically, after the material hole 1011 is rotated to the fourth position, the injection needle 43 sucks the radioactive drug solution from the drug solution bottle 41, and injects the radioactive drug solution into the capsule 401.
Further, in the present embodiment, the liquid medicine dripping device 40 further includes: pump 42, third bracket 44, seventh drive 45, clamp block 46, and purge bottle 47. The pump 42 is used to pump the radioactive liquid medicine in the liquid medicine bottle 41 into the injection needle 43. The seventh driving element 45 is disposed on the third bracket 44 and is capable of sliding along the third bracket 44, and the seventh driving element 45 is connected to the clamping block 46 for driving the clamping block 46 to move, where the clamping block 46 is used for clamping the injection needle 43. After the injection needle 43 injects the radioactive liquid medicine into the capsule body 401, the material hole 1011 rotates to the fifth station. The seventh driving member 45 slides along the third bracket 44 to align the injection needle 43 with the cleaning bottle 47, and the seventh driving member 45 drives the injection needle 43 to extend into the cleaning bottle 47 for cleaning. Alternatively, in this embodiment, the pump 42 may be a peristaltic pump or a syringe pump.
As shown in fig. 5, the fifth station of the automated preparation system is a bag closing station, and the bag closing station is provided with a bag closing device 50, where the bag closing device 50 includes: third driver 51, first thimble 52 and apron 53. The third driving piece 51 is located below the material disc 101, the first ejector pin 52 is connected with the third driving piece 51, and under the driving of the third driving piece 51, the first ejector pin 52 can extend into the material hole 1011 to push the capsule body 401 to be sleeved with the capsule cap 402.
Specifically, after the material hole 1011 is rotated to the fifth station, the push rod 102 is extended, pushing the receiving block 103 to move, so that the receiving hole 1031 is aligned with the material hole 1011 again. The third driving member 51 drives the first thimble 52 to move upwards, and the first thimble 52 stretches into the material hole 1011 to push the capsule 401 to move upwards, so that the capsule 401 is sleeved with the capsule cap 402.
Further, in the present embodiment, the push rod 102 is provided with the cover plate 53, when the capsule body 401 is fitted with the capsule cap 402, the cover plate 53 is moved above the accommodation hole 1031, and when the first ejector pin 52 pushes the capsule body 401 to move upward, the cover plate 53 abuts against the capsule cap 402, thereby preventing the capsule cap 402 from moving upward, so that the capsule body 401 is fitted with the capsule cap 402.
The capsule body 401 and the capsule cap 402 are sleeved to form a capsule, the material disc 101 rotates to a sixth station, the sixth station is a detection station, and the sixth station is provided with a detection device 60. The detection device 60 is used for detecting the appearance quality of the capsule.
As shown in fig. 6, the detection device 60 includes: a sliding mechanism, a second motor 63, a second suction cup 64 and a detection mechanism. The second motor 63 is connected with a sliding mechanism, the sliding mechanism can drive the second motor 63 to move transversely and longitudinally, the second sucker 64 is connected with the second motor 63, the second sucker 64 is used for sucking the sleeved capsules, and the detecting mechanism is used for detecting the appearance quality of the capsules.
Specifically, the slide mechanism includes: the first sliding table 61 and the second sliding table 62, the second sliding table 62 can slide along the first sliding table 61 to drive the second sucker 64 to move transversely, the second sliding table 62 can also move longitudinally to drive the second sucker 64 to move longitudinally, so that the second sucker 64 moves to the position of the capsule, the second sucker 64 sucks out the capsule from the accommodating hole 1031, and after sucking out, the second motor 63 drives the capsule to rotate, so that the detection mechanism can detect the appearance quality of the capsule.
Further, in the present embodiment, the detection mechanism includes: a vision camera 65, a light source 66 and a background plate 67, the background plate 67 being arranged opposite the vision camera 65, the light source 66 providing illumination for the vision camera 65. The second sliding table 62 can drive the capsule to lift so that the capsule is opposite to the vision camera 65, and when the second motor 63 rotates, the capsule is driven to rotate, the vision camera 65 performs high-speed shooting comparison on the rotating capsule, and the appearance quality of the capsule is judged through a software algorithm so as to reject unqualified products.
So far, the preparation of a single radioactive capsule is finished, and other stations can synchronously perform the preparation operation of the next radioactive capsule while the preparation of the radioactive capsule is finished.
Alternatively, in the present embodiment, the first slide table 61 and the second slide table 62 may be electric slide tables or pneumatic slide tables. It will be appreciated that: in this embodiment, the first sliding table 61 and the second sliding table 62 are in the prior art, and a person skilled in the art can set the first sliding table and the second sliding table according to related structures in the prior art, so that the description thereof is omitted.
Further, in the embodiment of the present invention, the first driving member 14, the second driving member 71, the third driving member 51, the fourth driving member 16, the fifth driving member 22, the sixth driving member 35, and the seventh driving member 45 may be air cylinders, electric cylinders, or hydraulic cylinders.
As shown in fig. 1, in the embodiment of the present invention, the automated preparation system further includes a control cabinet 200, a display screen 300 is disposed on the control cabinet 200, and the control cabinet 200 is a control system of the automated preparation system, and may perform production operation or parameter setting through the display screen 300, so as to implement automated preparation of the radioactive capsule.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and are not limiting; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims (10)

1. An automated preparation system for a radioactive capsule, comprising:
the rotating device comprises a material disc and a plurality of push rods, wherein a plurality of material holes are annularly formed in the material disc, each material hole is correspondingly provided with one push rod, one end of each push rod is provided with a containing hole, and when the push rods stretch out and draw back, the containing holes can be aligned with or staggered from the material holes;
the blanking device is used for conveying empty capsule shells into the accommodating holes and the material holes;
the separation device is arranged below the material tray and is used for separating the empty capsule shells so as to enable the capsule bodies to be contained in the material holes, and the capsule caps to be contained in the containing holes;
filling means for filling capsule powder into the capsule body;
a medicine dripping device for dripping the radioactive medicine liquid into the capsule body;
the capsule closing device is used for sleeving the capsule cap and the capsule body;
the material tray is rotatable, so that the material hole is driven to sequentially move to the blanking device, the filling device, the liquid medicine dripping device and the bag closing device, when the material hole is positioned at the blanking device and the bag closing device, the material hole is aligned with the containing hole, and when the material hole is positioned at the filling device and the liquid medicine dripping device, the material hole is staggered with the containing hole.
2. The automated preparation system of a radioactive capsule of claim 1, wherein the blanking apparatus comprises:
a first bracket;
the first hopper is arranged on the first bracket and is used for blanking the empty capsule shells;
the driving mechanism is arranged on the first bracket and is used for pushing part of the capsule body into the accommodating hole;
and the material pressing mechanism is used for pressing the empty capsule shell into the containing hole and the material hole.
3. The automated preparation system of a radioactive capsule of claim 2, wherein the drive mechanism comprises:
the first driving piece is arranged on the first bracket and can stretch out and draw back;
the guide block is connected with the first driving piece and is used for guiding the empty capsule shell so that the part of the capsule body can vertically fall into the accommodating hole under the pushing of the first driving piece.
4. The automated preparation system of a radioactive capsule of claim 1, wherein the separation device comprises:
the second driving piece is arranged below the material disc;
the first sucker is connected with the second driving piece, and the second driving piece is used for driving the first sucker to move towards the direction close to the capsule body so as to be attracted with the capsule body;
the second driving piece is also used for driving the first sucker to move in a direction away from the capsule cap after the first sucker is sucked with the capsule body so as to separate the capsule body from the capsule cap.
5. The automated preparation system of radioactive capsules of claim 1, further comprising a rejecting device for rejecting empty capsule shells that are not separated, the rejecting device comprising:
the photoelectric sensors are arranged above the material tray and are respectively used for detecting the capsule caps and the capsule bodies;
the ejection mechanism is arranged below the material disc and is used for ejecting the empty capsule shells which are not separated;
and the suction pipe is arranged above the material tray and is used for cooperating with the ejection mechanism to eject the empty capsule shells which are not separated out of the accommodating holes.
6. The automated preparation system of a radioactive capsule of claim 1, wherein the filling device comprises:
a second bracket;
the second hopper is arranged on the second bracket, and capsule powder is arranged in the second hopper;
the first motor is arranged above the second hopper;
the screw rod is connected with the first motor, one end of the screw rod penetrates through the second funnel and can extend into the capsule body, and the first motor is used for driving the screw rod to rotate so as to leak the capsule powder into the capsule body.
7. The automated preparation system of a radioactive capsule of claim 1, wherein the drug solution drip device comprises:
a medicine liquid bottle containing the radioactive medicine liquid;
and the injection needle is connected with the liquid medicine bottle and is used for injecting the radioactive liquid medicine into the capsule body filled with the capsule powder.
8. The automated preparation system of a radioactive capsule of claim 1, wherein the capsule closing device comprises:
the cover plate is arranged on the push rod and can move to the position above the accommodating hole;
the third driving piece is arranged below the material disc;
the first thimble is connected with the third driving piece, and under the drive of the third driving piece, the first thimble can stretch into in the material hole, promotes the capsule body to overlap with the capsule cap.
9. The automated preparation system of a radioactive capsule of claim 1, further comprising a detection device comprising:
a sliding mechanism;
the second motor is connected with the sliding mechanism, and the sliding mechanism can drive the second motor to move transversely and longitudinally;
the second sucker is connected with the second motor and is used for sucking the sleeved capsules;
and the detection mechanism is used for detecting the appearance quality of the capsule.
10. The automated preparation system of a radioactive capsule of claim 9, wherein the detection mechanism comprises:
a visual camera for photographing the appearance of the capsule;
the light source is arranged on the sliding mechanism and used for providing illumination for the vision camera;
and the background plate is arranged opposite to the vision camera.
CN202311707445.9A 2023-12-13 2023-12-13 Automatic preparation system of radioactive capsule Pending CN117379315A (en)

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CN219847410U (en) * 2023-05-05 2023-10-20 上海瑞替诺医药科技有限公司 Production equipment for capsule medicament

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Application publication date: 20240112