CN1173368A - Medicine for treating child asthma type bronchitis - Google Patents

Abstract

A medicine for treating asthmatic bronchitis of bady is prepared from straight ladybell root, earthworm and liquorice root through drying in air, crushing, low-temp decoction in water, alconol extraction, proportioning and granulating, and features high curative effect.

Description

Medicine for treating child asthma type bronchitis

The present invention relates to a kind of medicine of tracheitis, specifically is to be the medicine for treating child asthma type bronchitis that preparation of raw material forms with the Chinese herbal medicine.

Treating child asthma type bronchitis, cold place is a commonly encountered diseases, frequently-occurring disease in the north, it is dissatisfied to use the general effect of conventional therapy, and outbreak repeatedly easily, cause infant body constitution to descend, caused very big burden for the parents of hospitalized children body and mind, as the XIAOER KECHUANLING CHONGJI of selling on the market, have only 76% through treatment group clinical trial efficient, curative effect is slow, cure rate is lower, still can not solve patient's urgent need.

The object of the present invention is to provide a kind of nourishing YIN and moistening the lung, depressed lung-energy dispersing, clear respectful antitussive, antihistaminic increase, and remove the medicine for treating child asthma type bronchitis of the flat bone muscular spasm of bronchus.

Solution of the present invention is that Radix Adenophorae (Radix Glehniae) is lightly seasoned little sweet in the foundation side, and color cool in nature is white, and matter pine hollow can be gone into the lung yin nourishing, nourishing the lung to arrest cough, Pheretima have spasmolytic collateral dredging, helping inspiration to relieve asthma, the function of heat-clearing and toxic substances removing, modern pharmacological research has expansion bronchus, and antihistaminic is to bronchial contraction.The Radix Glycyrrhizae sweet in the mouth is flat, can spleen reinforcing and in, heat-clearing and toxic substances removing, nourishing the lung to arrest cough, coordinating the actions of various ingredients in a prescription (at this also clothes Radix Adenophorae (Radix Glehniae) or vow probably for a long time in cold, thus also have solid spleen with in meaning), again according to modern study, Radix Glycyrrhizae has the effect of alleviating smooth muscle spasm, effect also has the histamine of inhibition to increase effect with similar glucocorticoid sample, has nourishing YIN and moistening the lung, depressed lung-energy dispersing so full side is one, heat-clearing and toxic substances removing, spleen reinforcing and in, clear respectful cough-relieving, antihistaminic increases, remove effective prescription of the flat bone muscular spasm of bronchus, reached the purpose of treatment primary disease.

Medicine of the present invention is characterized in that it is to be made by the weight proportion of following component:

60～120 parts in 60～120 portions of Radix Glycyrrhizaes of 30～90 parts of Pheretimas of Radix Adenophorae (Radix Glehniae).

The preferred weight ratio scope of the present invention's prescription is:

40～100 parts in 40～100 portions of Radix Glycyrrhizaes of 40～80 parts of Pheretimas of Radix Adenophorae (Radix Glehniae).

Optimum weight proportioning of the present invention is:

90 parts in 90 portions of Radix Glycyrrhizaes of 60 parts of Pheretimas of Radix Adenophorae (Radix Glehniae).

Dosage form of the present invention is the graininess electuary.

Therapeutic effect of the present invention and advantage:

1, determined curative effect, instant effect, cure rate reaches 81%, and improvement rate reaches 15%, and total effective rate reaches 96%.

2, effect is lasting, and relapse rate is low, only need expense 2 courses of treatment.

3, be economy material benefit again, every patient pay wages 60-80 unit/about, the financial burden that alleviates infants ' parents greatly.

For showing the therapeutic effect of medicine of the present invention to treating child asthma type bronchitis, the present invention has carried out clinical observation to 221 infants, and selects medical history, and the state of an illness etc. are observed the treatment group by five hospitals according to practical department of pediatrics standard; Take medicine of the present invention; The XIAOER KECHUANLING CHONGJI that commercially available Xiaogan City pharmaceutical factory produces is taken by observation group, and matched group is selected the court's outpatient service and inpatient's 60 examples.Treatment group and matched group were a course of treatment with one month all, selected patient's 161 examples altogether, wherein male 106 people, women 55 people, 59 people below 1 years old, 1～3 years old 75 people, 3～8 years old 20 people, 8～14 years old 7 people.

Criterion of cure: heating is disappeared, cough, asthma disappears, and routine blood test is normal, pulmonary's depletion of YANG gonosome is levied, mental restoration, diet are normal.

Method of administration: boiled water is taken after mixing it with water, and 3 years old with interior each 5g, 4 years old～7 years old each 8g, and each 10g is three every day more than 8 years old.

Dosage form packing: granular pattern stamp, plastics paper bag packing, every bag 10 gram.

The course of treatment: with one month be a course of treatment, general disease time is shorter, obeys to get final product a course of treatment.The heavier person of outbreak can obey for 2～3 courses of treatment repeatedly.

Table 1: treatment group, treatment of control group situation synopsis

Group	The symptom age	Ill number	Bring down a fever			Cough with asthma disappears				Symptom and sign recovers
														1-2 days	3-5 days	More than 5 days	In 3 days	3-7 days	More than 7 days	No change	3-5 days	6-15 days	More than 15 days	More than January
			The treatment group	Below 1 year old	91	??21	35	??26	?21	??51	?16	??3	?27												?35	?26	??3
2-4 year	49	??5												4	??8	?11	??26	?5	??1	?14	?21	?7	??1
				5-7 year	14		2	??6	?1	??3	?9	??1	?3											??4	?6	??1
8-14 year	7														??1		??3	?4				?7
				Subtotal	161	??26	41	??41	?33	??83	?34	??5	?44											?60	?46	??5
Matched group	Below 1 year old	35												??2	8	??11	?3	??11	?14	??7	?5	?10	?16				??4
			2-4 year	17	??2	5	??5	?1	??4	?8	??4	?1	??4											?9	??3
	5-7 year	6													2	??2		??1	?3	??2		??1	?3			??2
			8-14 year	2			??1			?1	??1													?1	??1
	Subtotal	60												??4	15	??19	?4	??16	?26	??14	?6	??15	?29			??10
			Amount to		221	??30	56	??60	?37	??99	?60	??19	?5											??75	?75		??15

Table 2: treatment group, contrast groups Comparison of therapeutic situation statistical table

Handle and cure the invalid total effective percentage % X that takes a turn for the better ²Value P value

Treatment organizes 139 16 6 161 96.27 34.48＜0.005

Matched group 30 16 14 60 76.67

169???32????20????221

Embodiment:

Take by weighing raw material by following proportioning:

60 parts of Radix Adenophorae (Radix Glehniae), 90 parts of Pheretimas, 90 parts in Radix Glycyrrhizae.

Pharmaceutical technology:

Three flavors of getting it filled, airtight low temperature, decocting 2 times, collecting decoction filtered in each 1.5 hours, and filtrate is concentrated in right amount, adds 1.5 times of ethanol, stir evenly to leave standstill and make its precipitation, get supernatant and reclaim ethanol, be condensed into relative density and be 1.30～1.35 extractum, get three parts of a sucrose of extractum, the single-minded part in lake is made granule, dry, packed standby, every bag 10 gram, this product is faint yellow granule, the feeble QI flavor is sweet.

Claims (4)

1, a kind of medicine for the treatment of treating child asthma type bronchitis is characterized in that it is because following component weight proportion is made:

60～120 parts in 60～120 portions of Radix Glycyrrhizaes of 30～90 parts of Pheretimas of Radix Adenophorae (Radix Glehniae).

2, the medicine of treatment treating child asthma type bronchitis according to claim 1 is characterized in that the preferred weight ratio scope of filling a prescription is:

40～100 parts in 40～100 portions of Radix Glycyrrhizaes of 40～80 parts of Pheretimas of Radix Adenophorae (Radix Glehniae).

3, treatment medicine for treating child asthma type bronchitis according to claim 1, the optimum weight proportioning is:

90 parts in 90 portions of Radix Glycyrrhizaes of 60 parts of Pheretimas of Radix Adenophorae (Radix Glehniae).

4, be electuary according to claim 1,2 or 3 described treatment treating child asthma type bronchus pharmaceutical dosage forms.