CN1156623A - Compound capsule for treating tracheitis and asthma - Google Patents
Compound capsule for treating tracheitis and asthma Download PDFInfo
- Publication number
- CN1156623A CN1156623A CN 96119688 CN96119688A CN1156623A CN 1156623 A CN1156623 A CN 1156623A CN 96119688 CN96119688 CN 96119688 CN 96119688 A CN96119688 A CN 96119688A CN 1156623 A CN1156623 A CN 1156623A
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- asthma
- medicine
- tracheitis
- treatment
- chinese
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- 208000006673 asthma Diseases 0.000 title claims abstract description 22
- 206010044302 Tracheitis Diseases 0.000 title claims abstract description 17
- 239000002775 capsule Substances 0.000 title claims abstract description 13
- 150000001875 compounds Chemical class 0.000 title claims description 11
- 210000003734 kidney Anatomy 0.000 claims abstract description 10
- 210000000952 spleen Anatomy 0.000 claims abstract description 10
- 210000004072 lung Anatomy 0.000 claims abstract description 7
- 230000036039 immunity Effects 0.000 claims abstract description 5
- 239000003814 drug Substances 0.000 claims description 40
- 206010062717 Increased upper airway secretion Diseases 0.000 claims description 7
- 208000026435 phlegm Diseases 0.000 claims description 7
- 229940124584 antitussives Drugs 0.000 claims description 5
- 229940079593 drug Drugs 0.000 claims description 5
- 241000756943 Codonopsis Species 0.000 claims description 4
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 3
- 210000002826 placenta Anatomy 0.000 claims description 3
- -1 carbetapentane citrates Chemical class 0.000 claims description 2
- 229960003436 pentoxyverine Drugs 0.000 claims description 2
- 150000003118 prednisones Chemical class 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims 2
- 241001412627 Adenophora liliifolia Species 0.000 claims 1
- 244000144725 Amygdalus communis Species 0.000 claims 1
- 235000011437 Amygdalus communis Nutrition 0.000 claims 1
- 235000002722 Dioscorea batatas Nutrition 0.000 claims 1
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims 1
- 240000001811 Dioscorea oppositifolia Species 0.000 claims 1
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims 1
- 241000202807 Glycyrrhiza Species 0.000 claims 1
- 241000361919 Metaphire sieboldi Species 0.000 claims 1
- 240000002948 Ophiopogon intermedius Species 0.000 claims 1
- 244000131316 Panax pseudoginseng Species 0.000 claims 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims 1
- 241001522129 Pinellia Species 0.000 claims 1
- 244000226566 Psoralea corylifolia Species 0.000 claims 1
- 240000006079 Schisandra chinensis Species 0.000 claims 1
- 235000020224 almond Nutrition 0.000 claims 1
- 235000013399 edible fruits Nutrition 0.000 claims 1
- 210000003437 trachea Anatomy 0.000 claims 1
- 239000002131 composite material Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 12
- 201000010099 disease Diseases 0.000 description 11
- 230000000694 effects Effects 0.000 description 7
- 206010011224 Cough Diseases 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 4
- 230000000954 anitussive effect Effects 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 241000282414 Homo sapiens Species 0.000 description 2
- FQPFAHBPWDRTLU-UHFFFAOYSA-N aminophylline Chemical compound NCCN.O=C1N(C)C(=O)N(C)C2=C1NC=N2.O=C1N(C)C(=O)N(C)C2=C1NC=N2 FQPFAHBPWDRTLU-UHFFFAOYSA-N 0.000 description 2
- 229960003556 aminophylline Drugs 0.000 description 2
- 206010006451 bronchitis Diseases 0.000 description 2
- 239000000812 cholinergic antagonist Substances 0.000 description 2
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 description 2
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 description 2
- 239000003172 expectorant agent Substances 0.000 description 2
- 230000003419 expectorant effect Effects 0.000 description 2
- 208000030603 inherited susceptibility to asthma Diseases 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000002685 pulmonary effect Effects 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- 230000002048 spasmolytic effect Effects 0.000 description 2
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- AKJDEXBCRLOVTH-UHFFFAOYSA-N Carbetapentane citrate Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O.C=1C=CC=CC=1C1(C(=O)OCCOCCN(CC)CC)CCCC1 AKJDEXBCRLOVTH-UHFFFAOYSA-N 0.000 description 1
- 239000003390 Chinese drug Substances 0.000 description 1
- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- PWWVAXIEGOYWEE-UHFFFAOYSA-N Isophenergan Chemical compound C1=CC=C2N(CC(C)N(C)C)C3=CC=CC=C3SC2=C1 PWWVAXIEGOYWEE-UHFFFAOYSA-N 0.000 description 1
- 235000003143 Panax notoginseng Nutrition 0.000 description 1
- 241000180649 Panax notoginseng Species 0.000 description 1
- 241000237636 Pheretima Species 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 229940098166 bactrim Drugs 0.000 description 1
- 229940098391 carbetapentane citrate Drugs 0.000 description 1
- 229960003291 chlorphenamine Drugs 0.000 description 1
- 210000004081 cilia Anatomy 0.000 description 1
- 229960004126 codeine Drugs 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 229940107333 phenergan Drugs 0.000 description 1
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 description 1
- 229960004618 prednisone Drugs 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 229960005404 sulfamethoxazole Drugs 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A composite capsule taken orally is suitable to cure tracheitis and asthma, nourish lung, spleen and kidney, and improve immunity and features quick action and low by-effect.
Description
The invention belongs to a kind of medical oral class medicine product, a kind of specifically antiinflammatory is efficiently reduced phlegm, antiasthmatic-antitussive, supports the lung strengthening spleen, tonifying kidney, improves the immunity of body, reaches the oral administered compound capsule of treatment tracheitis, asthma.
Tracheitis, asthma are a kind of commonly encountered diseases and frequently-occurring disease.Early on the books on China's medical book, be referred to as " cough illness ".The chronic tracheitis prevalence is that the person is up to about 15% more than 3.82%, 50 years old, and bronchial asthma is up to 5.29%, and child's prevalence is at country variant 0.7～19.1%, seriously harm humans health and labour force.This disease is easily examined refractory, is a big difficult and complicated illness of medical domain.The doctor does not have obvious, specific medicine to tracheitis, treatment of asthma, the western medicine effect is bad separately, though resemble the antitussive of dicough, phenergan syrup, aminophylline, the effectively strong antitussive action of codeine one class, but the fortune expectorant function of the columnar epithelial cell of inhibition bronchitis mucomembranous cilium and the contraction wriggling of smooth muscle, expectorant can not be discharged smoothly, can only make the state of an illness heavier, and the traditional Chinese medical science is used Chinese medicinal formulae, curative effect is very slow, and therapeutic effect is also undesirable at present.
New drug of the present invention antiinflammatory rapidly reduces phlegm, and antiasthmatic-antitussive is supported the lung strengthening spleen, tonifying kidney, improve the immunity of body, thereby provide a kind of have easy to use, instant effect, the treatment bronchitis for the treatment of both the principal and secondary aspects of a disease, the specially good effect oral administered compound capsule and the production method thereof of asthma.
The objective of the invention is that following mode realizes, a kind of compound capsule for the treatment of tracheitis, asthma, by forming with following composition:
60 of 60 tablets of carbetapentane citrates of 30 aminophyllines of bactrim
60 of 60 chlorphenamines of 90 prednisones of Radix Glycyrrhizae
Pheretima 5g Placenta Hominis 6g Radix Pseudostellariae 10g
Radix Codonopsis 10g Rhizoma Dioscoreae 10g Fructus Schisandrae Chinensis 3g
Pericarpium Citri Reticulatae 3g Fructus Psoraleae 5g 8g Radix Ophiopogonis
Radix Adenophorae (Radix Glehniae) 5g Fructus Mume 3g Radix Notoginseng 3g
Rhizoma Pinelliae 3g Fructus Perillae 5g Semen Armeniacae Amarum 5g
21 kinds of medicine compositions, with Chinese and western drugs pulverize separately mixing, incapsulate.
A kind of manufacture method for the treatment of tracheitis, asthma compound capsule is at first carried out wiper, chopping with the hard Chinese crude drug, then the standby light wine classification of institute is cleaned once, and it is standby to dry bake and parch; Second step was the different performance according to Western medicine and Chinese medicine, and Chinese medicine powder is broken into smalls, sieves; The 3rd step is with the Western medicine crushing screening.The 4th step is with the Chinese medicine and western medicine powder mixes, stir evenly.The 5th step will be with the medicine powder bedding-in, sieve, and behind the mixing, divides encapsulatedly, packs standby.
Solution of the present invention be control tracheitis, asthma disease according to doctor trained in Western medicine infection, eliminate the phlegm, antitussive, spasmolytic is relievingd asthma, and the traditional Chinese medical science is supported the sharp kidney of lung spleen invigorating, preventing phlegm from forming and stopping coughing, QI invigorating is relievingd asthma, improve the principle of the immunologic function of human body, adopt oral way to reach the purpose of curing the disease, the Chinese and western drugs of selecting for use among the present invention all is the clinical middle common drug of Chinese and western medicine.Function by Western medicine is divided into three major types; One, control infection can be eliminated the infection and the inflammation thereof of tracheitis and pulmonary, and this type of medicine has multiple sulfamethoxazole; Two, eliminate the phlegm, cough medicine, the card shape that can improve disease is as cough, expectoration, this type of medicine has aminophylline, carbetapentane citrate etc.; Three, the spasmolytic antiallergic of relievining asthma, the person that mainly acts on the allergic constitution, because of the disease due to the irritated factor, this type of medicine has prednisone, chlorphenamine etc.Press the Chinese medicine functional classification, can be divided into five big classes: 1, reduce phlegm, relieving cough and asthma, can remove the symptom of disease, this type of medicine has Pericarpium Citri Reticulatae, Fructus Perillae, Semen Armeniacae Amarum etc.2, spleen reinforcing spleen invigorating, this type of medicine has Radix Codonopsis, the Rhizoma Pinelliae etc.3, the kidney invigorating is reinforced the kidney, and this type of medicine has Rhizoma Dioscoreae, Fructus Schisandrae Chinensis etc.4, the tonification medicine has Placenta Hominis, Radix Adenophorae (Radix Glehniae).5, improve body immunity, this type of medicine has Radix Codonopsis, Fructus Schisandrae Chinensis etc.This is according to the principle of Chinese medicine to tracheitis, asthma understanding: " it is marked on lung, and it is at spleen, and its root is at kidney ", though be the pathological changes of pulmonary, real and spleen, kidney two are dirty, and to lose void relevant.Therefore, based on the Chinese medicine prescription, cooperate Western medicine, Western medicine can play the effect of auxiliary treatment disease symptoms, controls its mark, based on Chinese medicine, supports the lung strengthening spleen, tonifying kidney, Zhi Qiben, and the combination of Chinese and Western medicine, treating both the principal and secondary aspects of a disease has improved the effect of curing the disease well.
For showing therapeutic effect of the present invention, select chronic tracheitis, asthmatic patient 180 examples, be divided into and use the treatment by Chinese herbs group, use western medicine group and three groups of the compound capsule groups of using this development.
Man's 108 examples, women 72 examples, the oldest 76 years old, minimum 6 years old mainly based on chronic tracheitis, bronchial asthma, was matched group with 80 examples wherein, form is a therapeutic effect analysis of experiments;
| Group | Number | The mean treatment time (my god) | Therapeutic outcome | |||
| Produce effects | Effectively | Recovery from illness | Invalid | |||
| The Western medicine group | ??40 | ???50 | ???5 | ???14 | ???16 | ????5 |
| Chinese drug-treated group | ??40 | ???50 | ???3 | ???12 | ???18 | ????7 |
| Compound capsule | ??100 | ???50 | ???8 | ???12 | ???79 | ????1 |
Its result shows that in the matched group, new compound capsule treatment tracheitis, asthma of making is effective, has improved cure rate greatly.
Claims (2)
1, a kind of compound capsule for the treatment of trachea, asthma is characterized in that having; 60 earthworm 5g of 60 tablets of chlorpheniramines of 90 tablets of prednisones of 60 Radix Glycyrrhizaes of 60 tablets of carbetapentane citrates of 30 aminophyllines of SMZco placenta 6g radix pseudostellariae 10g Radix Codonopsis 10g Chinese yam 10g fruit of Chinese magnoliavine 3g dried orange peel 3g Psoralea corylifolia 5g 8g tuber of dwarf lilyturf the root of straight ladybell 5g dark plum 3g pseudo-ginseng 3g tuber of pinellia 3g perillaseed 5g almond 5g
21 kinds of medicines by development processing such as pulverizing, sieve, are made into the capsule oral medicine.Antiinflammatory is promptly reduced phlegm, antiasthmatic-antitussive, support lung spleen invigorating, the kidney invigorating, improves the immunity of body, reaches the function of treatment tracheitis, asthma.
2, according to described a kind of its feature of compound capsule for the treatment of tracheitis, asthma of claim Chinese medicine and western medicine is synthesized one, encapsulated by wiper, oven dry, pulverizing, mixing, branch, pack and form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96119688 CN1156623A (en) | 1996-11-26 | 1996-11-26 | Compound capsule for treating tracheitis and asthma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96119688 CN1156623A (en) | 1996-11-26 | 1996-11-26 | Compound capsule for treating tracheitis and asthma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1156623A true CN1156623A (en) | 1997-08-13 |
Family
ID=5125922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96119688 Pending CN1156623A (en) | 1996-11-26 | 1996-11-26 | Compound capsule for treating tracheitis and asthma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1156623A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1058891C (en) * | 1997-08-28 | 2000-11-29 | 穆天真 | Medicine for treating child asthma type bronchitis |
| CN101095836B (en) * | 2007-07-16 | 2011-08-03 | 罗连珍 | Decoction medicine for treating chronic bronchitis and method for preparing the same |
| CN103417827A (en) * | 2013-07-25 | 2013-12-04 | 昆明理工大学 | Oral traditional Chinese medicine for treating chronic bronchitis and preparation method thereof |
-
1996
- 1996-11-26 CN CN 96119688 patent/CN1156623A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1058891C (en) * | 1997-08-28 | 2000-11-29 | 穆天真 | Medicine for treating child asthma type bronchitis |
| CN101095836B (en) * | 2007-07-16 | 2011-08-03 | 罗连珍 | Decoction medicine for treating chronic bronchitis and method for preparing the same |
| CN103417827A (en) * | 2013-07-25 | 2013-12-04 | 昆明理工大学 | Oral traditional Chinese medicine for treating chronic bronchitis and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |