CN117310141A

CN117310141A - Blood gas analysis module and blood gas analyzer

Info

Publication number: CN117310141A
Application number: CN202311194760.6A
Authority: CN
Inventors: 饶韦; 余洋; 刘海兰
Original assignee: Boatai Biotechnology Shenzhen Co ltd
Current assignee: Boatai Biotechnology Shenzhen Co ltd
Priority date: 2023-09-14
Filing date: 2023-09-14
Publication date: 2023-12-29

Abstract

The invention discloses a blood gas analysis module and a blood gas analyzer, wherein the blood gas analysis module comprises a base frame, a test card, a reagent kit, a driving mechanism and a shifting fork assembly, wherein the base frame is provided with a containing cavity for containing the reagent kit and an inserting port; the test card is arranged at the card inserting port and comprises a card main body, a switching valve and a sealing film arranged at the card main body, the card main body is provided with a groove, the switching valve is movably arranged at the groove and is configured to block the calibration pipeline and the test pipeline when in a first position, and the calibration pipeline is communicated with the test pipeline when in a second position; the kit comprises a control valve, wherein the control valve is used for controlling the reagent package to be communicated with or cut off from the calibration pipeline; the driving mechanism is arranged on the base frame and connected with the control valve and used for switching the working state of the control valve; the shift fork mechanism can shift the switch valve to enable the switch valve to be switched between a first position and a second position. Therefore, the shifting fork mechanism can shift the switching valve in the test card, so that the connection or disconnection of the calibration pipeline and the test pipeline is realized.

Description

Blood gas analysis module and blood gas analyzer

Technical Field

The embodiment of the invention relates to the field of medical appliances, in particular to a blood gas analysis module and a blood gas analyzer.

Background

The blood gas analyzer is a medical instrument commonly used for detecting the blood gas condition of a liquid to be tested, and is generally composed of a shell and a blood gas analysis module positioned in the shell, wherein the blood gas analysis module is used for analyzing and detecting the liquid to be tested and converting the detected result into an electric signal to be output. At present, a blood gas analysis module on the market comprises a base frame, a test card and a collection board, wherein a test point for blood gas analysis is arranged on a circuit board in the test card, and the circuit board is connected with the collection board through a connecting terminal.

When in testing, the external reagent pack is usually used for injecting the calibration liquid into the calibration pipeline of the test card for pre-calibration, then the test liquid is injected into the test pipeline of the test card, and the calibration pipeline is communicated with the test pipeline and converged to the reaction pipeline for testing. In general, when pre-scaling is performed, the scaling pipeline needs to be isolated from the test pipeline, so as to avoid that the scaling liquid enters the test pipeline to influence the subsequent test liquid.

At present, an elastic membrane is arranged at the intersection of the calibration pipeline and the test pipeline, and the elastic membrane can be acted on by external force before the calibration liquid is required to be introduced, so that the calibration pipeline is isolated from the test pipeline after the elastic membrane is deformed. However, there is a risk that the elastic membrane is broken by external force in this way, and the effect of isolating the calibration pipeline from the test tube is not achieved.

Disclosure of Invention

In order to solve the technical problems, the embodiment of the invention provides a blood gas analysis module, wherein a switch valve is arranged in a test card of the blood gas analysis module, and a calibration pipeline and a test pipeline can be isolated by pushing and pulling the switch valve.

The technical scheme adopted by the embodiment of the invention for solving the technical problems is as follows:

the blood gas analysis module comprises a base frame, a test card, a reagent box, a driving mechanism and a shifting fork mechanism, wherein the base frame is provided with a containing cavity and a bayonet, and the containing cavity is used for containing the reagent box; the test card is inserted into the insertion opening, the test card comprises a card main body, a switch valve and a sealing film arranged on the card main body, the card main body is provided with a groove used for communicating a calibration pipeline and a test pipeline, the switch valve is movably arranged in the groove, the switch valve is configured to block the joint of the calibration pipeline and the test pipeline when being in a first position, and the calibration pipeline is communicated with the test pipeline when being in a second position; the kit comprises a reagent shell, a reagent pack, a control valve and a first connecting component, wherein the reagent pack and the control valve are both accommodated in the reagent shell, the control valve part is exposed out of the reagent shell, the first connecting component is connected with the control valve and the calibration pipeline, the liquid inlet end of the control valve is connected with the reagent pack, and the control valve is used for controlling the reagent pack to be communicated with or cut off from the calibration pipeline; the driving mechanism is arranged on the base frame and connected with the control valve, and is used for switching the working state of the control valve; the shifting fork mechanism comprises a first driving motor and a shifting fork assembly, wherein the first driving motor is installed on the base frame, the shifting fork assembly is installed on an output shaft of the first driving motor, and the first driving motor is used for driving the shifting fork assembly to rotate so as to stir the switching valve, so that the switching valve is switched between a first position and a second position.

Optionally, the control valve includes a valve housing, a rotating member, a plurality of sealing members and a shielding member, wherein the valve housing is provided with an opening through which the rotating member extends, the rotating member is rotatably arranged on the valve housing, the valve housing is provided with a liquid inlet channel connected with the reagent pack and an output end connected with the calibration pipeline of the test card, the sealing member is arranged between the valve housing and the rotating member, the rotating member is provided with a concave part, a first communication hole and a second communication hole, the first communication hole and the second communication hole are respectively arranged on two sides of the concave part, the shielding member is arranged on the rotating member and shields the concave part, the first communication hole is connected with the output end of the valve housing, and one sealing member is annularly arranged at the output end of the valve housing. The rotating member is configured such that the liquid inlet passage communicates with the output end of the valve housing through the recess portion when in a first operation state, the output end of the valve housing is supplied with air from the second communication hole through the first communication hole to be supplied to the calibration pipe when in a second operation state, and the output end of the valve housing is in a blocking state under the action of the plurality of sealing members when in a third operation state.

Optionally, actuating mechanism includes rotating electrical machines, first fixed block and joint piece, first fixed block with the rotating electrical machines is connected, first fixed block is equipped with and is used for supplying the hole of dodging that the output shaft of rotating electrical machines stretches out, the output shaft of rotating electrical machines with the joint piece is connected, the joint piece be used for with the control valve joint.

Optionally, the joint piece includes first convex part and joint portion, first convex part set up in one side of joint portion, joint portion be equipped with be used for with the draw-in groove of control valve joint, first convex part be used for with the output shaft of rotating electrical machines.

Optionally, the driving mechanism further includes a first photoelectric sensor, the first photoelectric sensor is mounted on the first fixing block, the clamping block further includes a second protruding portion, the second protruding portion and the first protruding portion are arranged on the same side of the clamping portion at intervals, and the first photoelectric sensor is used for detecting a position where the second protruding portion is located.

Optionally, the shifting fork assembly comprises a connecting piece, an elastic piece, a first shifting lever and a second shifting lever, wherein the connecting piece is sleeved on an output shaft of the first driving motor, the first shifting lever and the second shifting lever are rotatably installed on the connecting piece and are arranged at intervals, and the elastic piece is connected with the first shifting lever and the second shifting lever; when the first driving motor drives the connecting piece to rotate along a first direction, the first deflector rod can stir the switch valve to the first position, and when the first driving motor drives the connecting piece to rotate along a second direction, the second deflector rod can stir the switch valve to the second position.

Optionally, the shift fork mechanism still includes fixed block and second photoelectric sensor, the fixed block is connected the bed frame with first driving motor, be provided with first arch on the fixed block, the connecting piece is provided with the second arch, works as first driving motor drive the connecting piece rotates, just first protruding butt when the second is protruding, first driving lever is shifted the ooff valve to first position, second photoelectric sensor install in the fixed block, second photoelectric sensor is used for detecting whether the second is protruding to reach the position of predetermineeing.

Optionally, the blood gas analysis module still include press card mechanism and set up in the circuit board of bed frame, press card mechanism includes press card subassembly and flexible drive piece, flexible drive piece is located the bed frame, flexible end of flexible drive piece with press card subassembly is connected, flexible drive piece is used for the drive press card subassembly is close to or keeps away from the test card, the test card is equipped with the notch, works as flexible drive piece drive press card subassembly to be close to when the test card, press card subassembly to press the notch, so that the test card towards the circuit board removes, the test card with the connecting terminal of circuit board is connected.

Optionally, the press-clamping assembly comprises a plug-in connector and a guide piece, the plug-in connector comprises a connecting block connected with the telescopic driving piece and a claw portion arranged on one side of the connecting block, the connecting block is provided with a guide hole, one end of the guide piece is connected with the base frame, the other end of the guide piece is inserted into the guide hole, the claw portion is provided with an inclined surface, and the claw portion is used for propping against the notch.

The technical problems of the embodiment of the invention are solved by adopting the following technical scheme:

a blood gas analyzer comprises the blood gas analysis module.

The embodiment of the invention has the beneficial effects that: the blood gas analysis module comprises a base frame, a test card, a reagent kit, a driving mechanism and a shifting fork assembly, wherein the base frame is provided with a storage cavity and a bayonet, and the storage cavity is used for accommodating the reagent kit; the test card is inserted into the card insertion port and comprises a card main body, a switching valve and a sealing film, wherein the card main body is provided with a groove used for communicating the calibration pipeline and the test pipeline, the switching valve is movably arranged in the groove and is configured to block the joint of the calibration pipeline and the test pipeline when the switching valve is in a first position, and the calibration pipeline is communicated with the test pipeline when the switching valve is in a second position; the kit comprises a reagent shell, a reagent pack, a control valve and a first connecting component, wherein the reagent pack and the control valve are both accommodated in the reagent shell, the control valve part is exposed out of the reagent shell, the first connecting component is connected with the control valve and the calibration pipeline, the liquid inlet end of the control valve is connected with the reagent pack, and the control valve is used for controlling the reagent pack to be communicated with or cut off from the calibration pipeline; the driving mechanism is arranged on the base frame and connected with the control valve, and is used for switching the working state of the control valve; the shifting fork mechanism comprises a first driving motor and a shifting fork assembly, the first driving motor is installed on the base frame, the shifting fork assembly is installed on an output shaft of the first driving motor, and the first driving motor is used for driving the shifting fork assembly to rotate so as to shift the switching valve, so that the switching valve is switched between a first position and a second position. Through the blood gas analysis module of above-mentioned structure, the shift fork subassembly can stir the ooff valve in the test card to realize calibration pipeline and test pipeline intercommunication or cut off, compare in pressing the elastic membrane of test card and make it warp in order to isolate the mode of calibration pipeline and test pipeline, avoided the test card to appear the risk of damage, be favorable to improving blood gas analysis module's stability and security performance.

Drawings

One or more embodiments are illustrated by way of example and not limitation in the figures of the accompanying drawings, in which like references indicate similar elements, and in which the figures of the drawings are not to be taken in a limiting sense, unless otherwise indicated.

FIG. 1 is a schematic diagram of a blood gas analysis module according to one embodiment of the present application;

FIG. 2 is a schematic diagram of another view of FIG. 1;

FIG. 3 is an exploded view of the structure of FIG. 1;

FIG. 4 is a schematic diagram of the structure of the test card of FIG. 3;

FIG. 5 is an exploded view of a portion of the structure of FIG. 4;

FIG. 6 is a schematic view of another view of FIG. 4;

FIG. 7 is a cross-sectional view of a test card;

FIG. 8 is a schematic view of the switch valve of FIG. 5;

FIG. 9 is a schematic diagram of the connection of a test card, a kit and a negative pressure device;

FIG. 10 is a schematic diagram of the structure of a control valve in the kit;

FIG. 11 is an exploded view of the structure of FIG. 10;

FIG. 12 is a schematic view of another view of FIG. 11;

FIG. 13a is a schematic illustration of the control valve in a first control state;

FIG. 13b is a schematic view of FIG. 13a taken along section line AA;

FIG. 14a is a schematic illustration of the control valve in a second control state;

FIG. 14b is a schematic view of FIG. 14a taken along section line BB;

FIG. 15a is a schematic illustration of the control valve in a third control state;

FIG. 15b is a schematic view of FIG. 15a taken along section line CC;

FIG. 16 is an exploded view of a portion of the structure of FIG. 3;

FIG. 17 is a schematic view of another view of FIG. 16;

FIG. 18 is a schematic view of the drive mechanism of FIG. 16;

FIG. 19 is an exploded view of the structure of FIG. 18;

FIG. 20 is a schematic view of the fork mechanism of FIG. 16;

FIG. 21 is an exploded view of the structure of FIG. 20;

FIG. 22 is a schematic view of the fork assembly of FIG. 21;

FIG. 23 is a schematic view of the heating assembly of FIG. 16;

FIG. 24 is an exploded view of the structure of FIG. 23;

FIG. 25 is a schematic view of a portion of the structure of FIG. 3;

FIG. 26 is a schematic view of the other view of FIG. 25;

FIG. 27 is an exploded view of the structure of FIG. 25;

FIG. 28 is a schematic view of the connection of the compression card assembly and telescoping drive of FIG. 27;

FIG. 29 is a schematic view of the other view of FIG. 28;

FIG. 30 is a cross-sectional view of a blood gas analysis module;

FIG. 31a is a schematic view of the test card pre-loaded by the card pressing mechanism;

FIG. 31b is a schematic view of a card pressing mechanism pressing a test card;

FIG. 31c is a schematic view of the card pressing mechanism separated from the test card;

FIG. 32 is an exploded view of the negative pressure apparatus;

FIG. 33 is a block diagram of a blood gas analyzer according to another embodiment of the present application;

in the figure: 1. a blood gas analysis module; 2. a base frame; 3. a test card; 4. a kit; 5. a driving mechanism; 6. a fork mechanism; 7. a heating assembly; 8. a collection plate; 9. a card pressing mechanism;

21. a storage chamber; 22. a bayonet; 201. a first substrate; 202. a second substrate;

31. a card body; 32. a switch valve; 311. calibrating pipelines; 312. testing a pipeline; 313. a reaction pipeline; 314. a groove; 315. a lug; 316. a waste liquid pipeline; 317. a waste liquid tank; 318. a negative pressure pipeline; 319. a butt joint part; 321. a rod body; 322. a first seal ring; 3211. a passing groove; 323. a second seal ring; 324. a limiting block; 33. a circuit board; 331. a recessed region; 34. a notch; 35. double faced adhesive tape; 36. a sample introduction connector; 37. a sealing film; 3191. a clamping hole; 3601. a clamping hook; 361. a joint body; 362. a sample inlet tube; 363. sealing rubber rings;

41. a reagent shell; 42. a reagent pack; 43. a control valve; 44. a first connection assembly; 45. a second connection assembly; 46. a sealing block; 461. a sealing body; 462. a sealing head;

431. a valve housing; 432. a rotating member; 433. a seal; 434. a shield; 431a, a first valve housing; 431b, a second valve housing; 4311. an opening; 4312. a liquid inlet channel; 4313. a liquid outlet end; 4314. a limit convex ring; 4321. a recessed portion; 4322. a first communication hole; 4323. a second communication hole; 441. a first connecting pipe; 442. a first pin; 451. a second connecting pipe; 452. a second pin;

51. A rotating electric machine; 52. a first fixed block; 53. a clamping block; 54. a first photosensor;

531. a first convex portion; 532. a clamping part; 5321. a clamping groove; 533. a second convex portion;

61. a first driving motor; 62. a fork assembly; 63. a second fixed block; 64. a second photosensor;

621. a connecting piece; 622. an elastic member; 623. a first deflector rod; 624. a second deflector rod; 6211. a connection part; 6212. a mounting part; 6213. a ring portion; 62111. a socket hole; 62121. a limit opening; 631. a first protrusion; 6214. a second protrusion; 632. a socket joint part; 633. an arm section;

71. a heat insulating member; 72. a heat conductive plate; 73. a heating sheet; 74. a cover plate; 711. a hollowed-out area; 712. a slide hole; 713. positioning columns; 721. positioning holes; 722. a concave region; 723. a temperature measuring hole;

81. a connection terminal;

91. a press-clamping assembly; 92. a telescopic driving member; 93. a fourth photosensor;

911. a plug-in component; 912. a guide member; 913. an elastic member; 9111. a connecting block; 9112. a claw part; 91111. a guide hole; 91121. an inclined surface;

10. a pressing member; 11. a spring clip piece; 12. a third photosensor; 101. a butt part; 102. an extension part;

13. a negative pressure device; 14. a fifth photosensor;

131. A second driving motor; 132. a fixed bracket; 133. an air extracting pump; 134. sealing sleeve; 1321. a mounting cylinder; 1322. a fixed bottom plate; 1331. a pump body; 1332. a seal ring; 1333. and (3) a piston.

15. A housing; 16. a main board; 17. a control board; 18. a display screen; 20. blood gas analyzer.

Detailed Description

In order that the invention may be readily understood, a more particular description thereof will be rendered by reference to specific embodiments that are illustrated in the appended drawings. It will be understood that when an element is referred to as being "fixed" to another element, it can be directly on the other element or one or more intervening elements may be present therebetween. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or one or more intervening elements may be present therebetween. The terms "upper," "lower," "inner," "outer," "vertical," "horizontal," and the like as used in this specification, refer to an orientation or positional relationship based on that shown in the drawings, merely for convenience of description and to simplify the description, and do not denote or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the invention. Furthermore, the terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and/or" as used in this specification includes any and all combinations of one or more of the associated listed items.

In addition, the technical features mentioned in the different embodiments of the invention described below can be combined with one another as long as they do not conflict with one another.

As shown in fig. 1-3, a blood gas analysis module 1 according to one embodiment of the present application includes a base frame 2, a test card 3, a kit 4, a driving mechanism 5 and a fork mechanism 6, wherein the base frame 2 is provided with a storage cavity 21 and a bayonet 22, the test card 3 is inserted into the bayonet 22, the kit 4 is stored in the storage cavity 21, and the driving mechanism 5 and the fork mechanism 6 are both mounted on the base frame 2. The driving mechanism 5 is connected with the reagent kit 4, and the driving mechanism 5 is used for driving the reagent kit 4 to supply the calibration liquid to the reagent card or stop supplying the calibration liquid. The shifting fork mechanism 6 is used for shifting the switch valve 32 of the test card 3, so that the position of the switch valve 32 is changed.

The base frame 2 comprises a first substrate 201 and a second substrate 202, the first substrate 201 and the second substrate 202 can be detachably connected, can be connected through screws or bolts and the like, can be connected through buckling, can be clamped through a convex column with a blind hole and a clamping column capable of being inserted into the blind hole, can be magnetically attracted and connected through a magnet, and can be connected through other modes. In the present embodiment, the first substrate 201 extends partially toward the second substrate 202 and forms a receiving chamber 21 for receiving the reagent cartridge 4, and the first substrate 201 is provided with a card slot 22 for inserting the test card 3.

In some embodiments, as shown in fig. 4-7, the test card 3 includes a card body 31, an on-off valve 32, and a sealing film 37, the on-off valve 32 is installed in the card body 31, the on-off valve 32 is used to control the communication or blocking of the pipeline in the card body 31, and the sealing film 37 is provided in the card body 31. Specifically, the card body 31 is provided with a calibration pipeline 311, a test pipeline 312, a reaction pipeline 313 and a groove 314, the calibration pipeline 311 is communicated with the reaction pipeline 313, the groove 314 is arranged between the calibration pipeline 311 and the test pipeline 312, and the reaction pipeline 313 is used for performing a reaction test on the liquid to be tested. The on-off valve 32 is movably provided in the recess 314, the on-off valve 32 being configured to block the calibration line 311 and the test line 312 when in the first position, and the calibration line 311 being in communication with the test line 312 when in the second position. The sealing film 37 is used for shielding the calibration pipeline 311, the test pipeline 312, the reaction pipeline 313 and the groove 314 to avoid liquid leakage. In this embodiment, the sealing film 37 may be a single sided adhesive backed PET film.

It can be understood that when the blood gas analysis module is tested, the test environment is required to be known first, namely calibration is performed, the influence of factors such as humidity and temperature of the test environment on the test result is avoided, the reference value of the environment can be obtained after calibration is completed, and the test is performed according to the obtained reference value as a basis, so that the test accuracy can be ensured. In the present embodiment, the on-off valve 32 may be switched by manual pulling, or may be moved relative to the card body 31 by a link mechanism.

In some embodiments, as shown in fig. 8, the on-off valve 32 includes a rod 321 and a first sealing ring 322, where the rod 321 is provided with a through groove 3211, and the first sealing ring 322 is sleeved on the rod 321 and located at one side of the through groove 3211. When the switch valve 32 is at the first position, the first sealing ring 322 seals the calibration pipeline 311 and the test pipeline 312, and when the switch valve 32 is at the second position, the through groove 3211 is communicated with the calibration pipeline 311 and the test pipeline 312. It will be appreciated that by measuring the depth of the groove 314, the position of the connection between the test line 312 and the calibration line 311, and the length of the rod 321, the position of the first seal 322 can be determined, so that the first seal 322 can seal the connection between the test line 312 and the calibration line 311 when the on-off valve 32 extends into the groove 314 by a predetermined first length, and the through slot 3211 communicates the calibration line 311 and the test line 312 when the on-off valve 32 extends into the groove 314 by a predetermined second length.

Further, the on-off valve 32 further includes a second sealing ring 323, the second sealing ring 323 is sleeved on the rod body 321, the second sealing ring 323 is located at the other side of the passing groove 3211, and the second sealing ring 323 is used for sealing the groove 314. In this way, the outside can be prevented from entering the card body 31 through the groove 314, and the liquid to be tested can be prevented from leaking to the outside through the gap between the rod 321 and the groove 314.

In some embodiments, referring to fig. 5 and 8, the switch valve 32 further includes a stopper 324 located outside the groove 314, the stopper 324 is connected with the rod 321, and the card body 31 further includes a stopper lug 315 protruding from a side end of the card body 31; the stopper 324 abuts the stopper ledge 315 when the on-off valve 32 is in the first position, and the stopper 324 abuts the sidewall edge of the recess 314 when the on-off valve 32 is in the second position. In this way, when the joint of the calibration pipeline 311 and the test pipeline 312 needs to be blocked, the limiting block 324 is only required to be pushed to be abutted against the limiting lug 315, and when the calibration pipeline 311 is required to be communicated with the test pipeline 312, the limiting block 324 is only required to be pushed to be abutted against the edge of the side wall of the groove 314, so that the operation is convenient.

In some embodiments, the card body 31 is further provided with a waste liquid pipe 316 and a waste liquid tank 317, one end of the waste liquid pipe 316 is communicated with the reaction pipe 313, the other end of the waste liquid pipe 316 is communicated with the waste liquid tank 317, and the waste liquid tank 317 is used for containing waste liquid, which can be calibration liquid and test liquid after testing at the reaction pipe 313. Further, the card main body 31 is further provided with a negative pressure pipeline 318, one end of the negative pressure pipeline 318 is communicated with the waste liquid tank 317, the other end of the negative pressure pipeline 318 is used for being connected with the negative pressure device 13, and the negative pressure device 13 can provide a negative pressure environment for the waste liquid pipeline 316, the calibration pipeline 311 and the test pipeline 312 so as to promote the flow of calibration liquid or test liquid.

It will be appreciated that the calibration solution after reaction in the reaction pipeline 313 needs to be pumped to the waste liquid tank 317 under negative pressure to open the switch valve 32, the solution to be tested in the sample container is sucked into the test pipeline 312 under the action of the negative pressure, the solution to be tested moves towards the reaction pipeline 313 under the action of the negative pressure, and flows towards the waste liquid tank 317 after the reaction in the reaction pipeline 313 is completed. The sealing film 9 also shields the waste liquid line 27, the waste liquid tank 26, and the negative pressure line 28. It is to be noted that the connection of the waste liquid line 316 to the waste liquid tank 317 is provided at a position where the waste liquid tank 317 is distant from the reaction line 313, which is advantageous in preventing the flow of waste liquid from the waste liquid tank 317 to the waste liquid line 316 when the test card 3 is placed vertically.

It will be appreciated that, as shown in fig. 6, the test card 3 further includes a circuit board 33, the circuit board 33 is disposed on the card body 31, and test points of the circuit board 33 are located in the reaction pipeline 313, where the test points are used for collecting preset electrical signals. The preset electrical signal refers to the voltage, current and impedance measured by the test point in the liquid to be tested. In this embodiment, the card body 31 is provided with a recessed area 331 for fixing the circuit board 33, and the circuit board 33 and the card body 31 may be bonded by a double sided tape 35, or may be connected by a screw, or may be connected by other means.

In some embodiments, referring to fig. 5 and fig. 9, the test card 3 further includes a sample connector 36, the card body 31 is provided with a docking portion 319, a liquid inlet end of the test pipeline 312 is disposed in the docking portion 319, and the sample connector 36 is mounted on the docking portion 319, and a specific connection manner thereof is not limited, and may be realized by a clamping or screwing manner, for example. In this embodiment, the sample connector 36 and the docking portion 319 are connected by means of a clamping connection, specifically, the sample connector 36 is provided with a clamping hook 3601, the docking portion 319 is provided with a clamping hole 3191, and the clamping hook 3601 is clamped in the clamping hole 3191, so that the sample connector 36 and the clamping main body 31 are relatively fixed.

Further, the sample connector 36 includes a connector body 361 and a sample tube 362 connected to the connector body 361, the sample tube 362 penetrates the connector body 361, and the sample tube 362 is used for docking with a liquid inlet end of the test pipeline 312. In this embodiment, a sealing rubber ring 363 is disposed at one end of the sample inlet tube 362 near the test pipeline 312, the sealing rubber ring 363 is used to abut against the inner wall surface of the abutting portion 319, so as to ensure that when the joint body 361 is clamped to the abutting portion 319, the sample inlet tube 362 is sealed from leaking from the liquid inlet end of the test pipeline 312, and the other end of the sample inlet tube 362 can be connected to an external sample inlet container. As shown in fig. 9, fig. 9 shows a gas inlet manner when the sample connection 36 is connected to the sample container, that is, external gas can be introduced through a gap between both the connection body 361 and the sample tube 362 and the sample container.

In some embodiments, as shown in fig. 9, the kit 4 includes a reagent case 41, a reagent pack 42, a control valve 43, and a first connection assembly 44, wherein the reagent pack 42 and the control valve 43 are both contained in the reagent case 41, and the control valve 43 is partially exposed outside the reagent case 41, the first connection assembly 44 is connected to the control valve 43 and the calibration pipeline 311, a liquid inlet end of the control valve 43 is connected to the reagent pack 42, the control valve 43 is connected to the driving mechanism 5, and the driving mechanism 5 is used for switching the working state of the control valve 43.

In some embodiments, the reagent pack 42 is connected to the inlet channel 4312 of the control valve 43, and the first connection assembly 44 is connected to the output of the control valve 43 and the calibration line 311 of the reagent card. Wherein the control valve 43 is configured such that, when in the first operating state, the output end of the control valve 43 is in communication with the calibration line 311 of the reagent card, when in the second operating state, the output end of the control valve 43 is isolated from the calibration line 311 of the reagent card, the control valve 43 can supply gas to the calibration line 311 of the test card 3, and when in the third operating state, the output end of the control valve 43 is in a blocking state.

In some embodiments, the reagent casing 41 includes a first sub-casing and a second sub-casing that are connected, and the first sub-casing and the second sub-casing may be connected in a thickness direction or in a direction perpendicular to the thickness direction, and may be specifically set as required. In the present embodiment, the first sub-case and the second sub-case are connected in the thickness direction of the reagent case 41. It is understood that the first sub-housing and the second sub-housing may be connected by a snap connection, a connection 621 such as a screw, or other manners.

In some embodiments, as shown in fig. 10 to 12, the control valve 43 includes a valve housing 431, a rotary member 432, a plurality of sealing members 433, and a shutter 434, the rotary member 432 is rotatably provided to the valve housing 431, the valve housing 431 is provided with an opening 4311 through which the rotary member 432 is exposed, and is provided with a liquid inlet passage 4312 connected to the reagent pack 42 and a liquid outlet end 4313 for connection to the calibration line 311 of the reagent card, and the sealing members 433 are provided between the valve housing 431 and the rotary member 432. The rotary member 432 is provided with a recess 4321, a first communication hole 4322 and a second communication hole 4323, the first communication hole 4322 and the second communication hole 4323 are respectively disposed at two sides of the recess 4321, the shielding member 434 is disposed on the rotary member 432 and shields the recess 4321, the first communication hole 4322 is connected with an output end of the valve housing 431, and a sealing member 433 is disposed around the output end of the valve housing 431;

the rotary member 432 is configured such that, in a first operating state, the liquid inlet passage 4312 communicates with the liquid outlet end 4313 through the recess 4321, and, in a second operating state, the liquid outlet end 4313 of the valve housing 431 is supplied with air from the second communication hole 4323 through the first communication hole 4322 to be delivered to the calibration pipe 311, and, in a third operating state, the output end of the valve housing 431 is in a blocked state by the plurality of sealing members 433.

In some embodiments, the valve housing 431 includes a first valve housing 431a and a second valve housing 431b, the first valve housing 431a and the second valve housing 431b are detachably connected, the first valve housing 431a is provided with an opening 4311, and the second valve housing 431b is provided with a liquid inlet channel 4312 and an output end for outputting the calibration liquid.

As can be understood, referring to fig. 13a and 13b, when the rotary member 432 is in the first working state, the calibration fluid in the reagent pack 42 flows in from the fluid inlet channel 4312 of the second valve housing 431b, and flows out from the first communication hole 4322 after entering the recess 4321 through the second communication hole 4323, and the calibration fluid can flow from the fluid outlet end 4313 of the second valve housing 431b toward the calibration pipeline 311 due to the communication between the first communication hole 4322 and the fluid outlet end 4313 of the second valve housing 431 b.

Referring to fig. 14a and 14b, when the rotary member 432 is in the second working state, i.e. the rotary member 432 rotates to another position relative to the first valve housing 431a under the external action, there is a gap between the rotary member 432 and the second valve housing 431b, the second communication hole 4323 is staggered with the liquid inlet channel 4312, and air can enter the recess 4321 through the second communication hole 4323 and then be delivered to the liquid outlet end 4313 of the second valve housing 431b through the first communication hole 4322, so as to ensure that air enters the calibration pipeline 311 from the first connection assembly 44, thereby pushing the calibration liquid in the calibration pipeline 311 to move.

Referring to fig. 15a and 15b, when the rotary member 432 is in the third working state, i.e. the rotary member 432 rotates to a further position relative to the reagent case 41 under the external action, the second communication hole 4323 is surrounded by the sealing member 433 and is not communicated with the liquid inlet channel 4312, the first communication hole 4322 is also surrounded by the other sealing member 433, at this time, the calibration liquid of the reagent pack 42 cannot enter the recess 4321 through the liquid inlet channel 4312, and air cannot enter the first communication hole 4322, which is equivalent to the liquid outlet end 4313 of the second valve housing 431b in a blocking state.

In some embodiments, referring to fig. 11 and 12 again, at least three sealing members 433 are provided, the second valve housing 431b is provided with at least three spacing protruding rings 4314, one spacing protruding ring 4314 is provided with a sealing member 433, wherein the periphery of the outlet end of the liquid inlet channel 4312 is provided with a spacing protruding ring 4314, and the output end is provided with a spacing protruding ring 4314. The limiting collar 4314 is used to limit the movement of the seal 433 to reduce the risk of the rotation member 432 moving the seal 433 when rotated relative to the second valve housing 431 b. In the present embodiment, the number of the sealing members 433 is five, the number of the limiting collars 4314 is five, wherein four limiting collars 4314 are equally spaced around one limiting collar 4314, and the output end of the liquid inlet channel 4312 is located at the center of one limiting collar 4314, and the output end of the second valve housing 431b is located in the middle limiting collar 4314.

It will be appreciated that the rotary member 432 may be configured with different angles of rotation as desired to switch between the first, second and third operating states. Illustratively, when the rotary member 432 is switched from the first operating state to the second operating state, the rotary member 432 is only required to be rotated by 45 °, and when the rotary member 432 is switched from the second operating state to the third operating state, the rotary member 432 is also required to be rotated again by 45 °.

In some embodiments, referring to fig. 9 again, the first connection assembly 44 includes a first connection pipe 441 and a first contact pin 442, one end of the first connection pipe 441 is connected to the output end of the control valve 43, the other end of the first connection pipe 441 is connected to one end of the first contact pin 442, and the other end of the first contact pin 442 penetrates out of the reagent case 41 and is inserted into the calibration pipe 311, so that the calibration liquid can be provided to the calibration pipe 311 through the first connection pipe 441 and the first contact pin 442 in the reagent pack 42.

In some embodiments, the kit 4 further comprises a second connection assembly 45, the second connection assembly 45 being configured to connect the negative pressure device 13 to the negative pressure line 318 of the test card 3, such that the negative pressure device 13 may provide a negative pressure environment for the test card 3. In this embodiment, the second connection assembly 45 includes a second connection pipe 451 and a second pin 452, one end of the second connection pipe 451 is disposed on the reagent case 41 for connecting the negative pressure device 13, the other end of the second connection pipe 451 is connected to one end of the second pin 452, and the other end of the second pin 452 is inserted into the negative pressure pipeline 318. In this way, the negative pressure device 13 can provide a negative pressure environment into the test card 3 through the second connection pipe 451 and the second pins 452.

Further, the kit 4 further comprises a sealing block 46, the sealing block 46 being mounted to the reagent vessel 41 at a region for the first connection assembly 44 and the second connection assembly 45 to pass through, the sealing block 46 being used to ensure sealing between the first pin 442 and the second pin 452 relative to the reagent vessel 41. In this embodiment, the sealing block 46 includes a sealing main body 461 and a sealing head 462, the sealing main body 461 abuts against the inner wall of the reagent case 41, the sealing head 462 extends out of the reagent case 41, and the first pin 442 and the second pin 452 are disposed on the sealing head 462, so that when the test card 3 is inserted into the card slot 22 and abuts against the reagent case 4, the sealing head 462 abuts against the calibration pipeline 311 and the negative pressure pipeline 318, so that the connection between the reagent case 4 and the test card 3 is sealed. In some embodiments, the sealing block 46 is made of a soft plastic material, and when the test card 3 presses against the reagent kit 4, the sealing head 462 of the sealing block 46 is pressed and deformed, so as to improve the sealing performance between the reagent kit 4 and the test card 3.

In some embodiments, as shown in fig. 16-18, the driving mechanism 5 includes a rotating motor 51, a first fixed block 52 and a clamping block 53, the first fixed block 52 is mounted on the base frame 2, the first fixed block 52 is connected with the rotating motor 51, the first fixed block 52 is provided with a avoiding hole for extending an output shaft of the rotating motor 51, the output shaft of the rotating motor 51 is connected with the clamping block 53, and the clamping block 53 is used for clamping with the control valve 43. In this embodiment, as shown in fig. 19, the locking block 53 includes a first protrusion 531 and a locking portion 532, the first protrusion 531 is disposed on one side of the locking portion 532, the locking portion 532 is provided with a locking slot 5321 for locking with the control valve 43, and the first protrusion 531 is connected to the output shaft of the rotating electrical machine 51, so that the rotation of the output shaft of the rotating electrical machine 51 will drive the locking block 53 to rotate, thereby driving the control valve 43 to switch working states. Further, the locking groove 5321 of the locking portion 532 is formed in a U shape, and a portion of the rotary member 432 located outside the reagent casing 41 is fitted into the locking groove 5321, so that the output shaft of the rotary motor 51 rotates with the rotary member 432 relative to the valve case 431, thereby switching the operating state of the control valve 43.

Further, the driving mechanism 5 further includes a first photoelectric sensor 54, the first photoelectric sensor 54 is mounted on the first fixed block 52, the clamping block 53 further includes a second protruding portion 533, the second protruding portion 533 and the first protruding portion 531 are disposed on the same side of the clamping portion 532 at intervals, the first photoelectric sensor 54 is configured to detect a position of the second protruding portion 533, and by detecting the second protruding portion 533, the rotating electric machine 51 can be angularly initialized, so as to initialize the operating state of the control valve 43. For example, the position of the rotating member 432 in the control valve 43 may be switched by taking the position of the rotating motor 51 when the first photosensor 54 detects the second boss 533 as the initial position and the position of the rotating member 432 in the control valve 43 as the position in one of the operating states, and then adjusting the position of the rotating member 432 by controlling the angle at which the rotating motor 51 rotates.

The on-off valve can be manually pushed by an external mechanism or can be pushed by an automatic mechanism, and in the embodiment, the on-off valve is switched in position by a shifting fork mechanism.

In some embodiments, as shown in fig. 16-17 and 20-22, the fork mechanism 6 includes a first driving motor 61 and a fork assembly 62, the first driving motor 61 is mounted on the base frame 2, the fork assembly 62 is mounted on an output shaft of the first driving motor 61, and the first driving motor 61 is used for driving the fork assembly 62 to rotate to toggle the switch valve 32, so that the switch valve 32 is switched between a first position and a second position.

As shown in fig. 22, the fork assembly 62 includes a connecting member 621, an elastic member 622, a first lever 623 and a second lever 624, the connecting member 621 is sleeved on the output shaft of the first driving motor 61, the first lever 623 and the second lever 624 are rotatably mounted on the connecting member 621 and are disposed at intervals, and the elastic member 622 is connected to the first lever 623 and the second lever 624. When the first driving motor 61 drives the connecting piece 621 to rotate along the first direction, the first shifting lever 623 can shift the switch valve 32 to the first position, when the first driving motor 61 drives the connecting piece 621 to rotate along the second direction, the second shifting lever 624 can shift the switch valve 32 to the second position, and the first direction and the second direction are opposite directions, for example, if the first direction is clockwise, the second direction is anticlockwise; conversely, if the first direction is counterclockwise, the second direction is clockwise.

The elastic member 622 may be a tension spring, a rubber band, or any other elastic member, as long as the elastic connection between the first lever 623 and the second lever 624 is achieved. In this embodiment, the elastic member 622 is a tension spring, and under the action of the tension spring, the first shift lever 623 and the second shift lever 624 can be pulled to close to each other, which is beneficial to rotationally compensating the first shift lever 623 or the second shift lever 624 when the first driving motor 61 loses steps, so as to ensure that the shift fork assembly 62 can shift the switch valve 32 to the first position or the second position under the driving of the first driving motor 61.

In some embodiments, the connection piece 621 includes a connection portion 6211, a mounting portion 6212, and a ring portion 6213 connected, the connection portion 6211 being provided with a socket hole 62111 for being socket-fitted to the output shaft of the first drive motor 61. The mounting portion 6212 and the body surface of the first driving motor 61 have a gap therebetween to avoid collision between the mounting portion 6212 and the body of the first driving motor 61 when the output shaft of the first driving motor 61 rotates, the mounting portion 6212 is used for mounting the first and second levers 623 and 624, the ring portion 6213 is provided with a limit opening 62121 for the first and second levers 623 and 624 to pass out, and the limit opening 62121 is used for limiting the range of rotation of the first and second levers 623 and 624. In this embodiment, the ring portion 6213 has a D-shape, and the number of the limiting openings 62121 is two, and the two limiting openings 62121 are symmetrically arranged. Both the first shift lever 623 and the second shift lever 624 may be mounted on the adapter post and hinged to the mounting portion 6212, and the adapter post may be riveted or snap-locked on the mounting portion 6212.

In some embodiments, as shown in fig. 20 to 21, the fork mechanism 6 further includes a second fixing block 63, the second fixing block 63 is connected to the base frame 2 and the first driving motor 61, a first protrusion 631 is provided on the second fixing block 63, a second protrusion 6214 is provided on the connecting piece 621, when the first driving motor 61 drives the connecting piece 621 to rotate along the first direction, and the second protrusion 6214 abuts against the first protrusion 631, the first lever 623 toggles the switch valve 32 to the first position, and when the first driving motor 61 drives the connecting piece 621 to rotate along the second direction, the second lever 624 toggles the switch valve 32 to the second position. The first protrusion 631 can prevent the first driving motor 61 from driving the fork assembly 62 to rotate beyond a safe angle, so as to prevent the fork assembly 62 from rotating too far to rotate normally and reversely. In the present embodiment, the second fixing block 63 includes a sleeve connection portion 632 and an arm portion 633 connected to the sleeve connection portion 632, the sleeve connection portion 632 is sleeved on the output shaft of the first driving motor 61 and connected to the main body of the first driving motor 61, and the arm portion 633 is detachably connected to the base frame 2.

In some embodiments, as shown in fig. 20, the fork mechanism 6 further includes a second photoelectric sensor 64, where the second photoelectric sensor 64 is mounted on the second fixing block 63, and the second photoelectric sensor 64 is used to detect whether the second protrusion 6214 reaches the preset position. The preset position refers to an extreme position to which the fork assembly 62 can rotate. When the second photoelectric sensor 64 detects the second protrusion 6214, it can be known that the fork assembly 62 has rotated to the limit position, and if the first driving motor 61 drives the fork assembly 62 to continue to rotate at this time, the angle of safe rotation will be exceeded. The second photoelectric sensor 64 is provided, so that the initialization position of the first driving motor 61 can be determined, that is, when the second photoelectric sensor 64 detects the second protrusion 6214, the position of the output shaft of the first driving motor 61 is taken as the initial position, and then the rotation angle of the first driving motor 61 can be known.

It should be understood that the fork mechanism 6 and the driving mechanism 5 may be mounted on the first substrate 201 or the second substrate 202, and in this embodiment, the fork mechanism 6 and the rotating mechanism are mounted on the first substrate 201, and the first substrate 201 is provided with a bayonet slot 22 for inserting the test card 3 and a window for inserting the fork assembly 62 into the bayonet slot 22, and the fork assembly 62 may toggle the switch valve 32 on the test card 3 through the window.

In some embodiments, referring to fig. 16 and 23-24, the blood gas analysis module 1 further includes a heating component 7, where the heating component 7 is mounted on the base frame 2, and the heating component 7 is used for heating the test card 3 by heating so that the test card 3 is at a preset test temperature. In this embodiment, the heating assembly 7 includes a heat insulating member 71, a heat conducting plate 72 and a heating plate 73, the heat insulating member 71 is provided with a hollowed-out area 711, the heat conducting plate 72 is mounted on the heat insulating member 71, the heating plate 73 is mounted on the heat conducting plate 72, and the heat insulating member 71 is used for preventing the heat conducting plate 72 from directly contacting with the test card 3. When heating is required, the heating plate 73 heats to a preset temperature and transmits heat to the heat-conducting plate 72 in a heat transfer mode, and the heat-conducting plate 72 heats the test card 3 through the hollowed-out area 711 of the heat-insulating member 71, so that a proper reaction environment is provided for the test card 3. The heating plate 73 is adhered to the heat conducting plate 72 by means of double-sided adhesive tape, and the preset test temperature is less than the failure temperature of the adhesive layer of the double-sided adhesive tape. The failure temperature refers to the temperature at which the adhesive layer of the double-sided adhesive loses adhesion, i.e., the temperature at which the double-sided adhesive between the heating element sheet and the heat conductive plate 72 falls off.

In some embodiments, the thermal shield 71 is provided with a slide hole 712, the slide hole 712 being for receiving an abutment 10, the abutment 10 being for abutting the test card 3.

In some embodiments, as shown in fig. 24, the heat-conducting plate 72 is provided with positioning holes 721, the heat-insulating member 71 is provided with positioning posts 713, and the positioning posts 713 are provided in the positioning holes 721 to achieve quick positioning and mounting of the heat-conducting plate 72 to the heat-insulating member 71. In the present embodiment, there are two positioning posts 713, two positioning posts 713 are respectively located at two sides of the heat insulation member 71, two positioning holes 721 are also respectively located at two sides of the heat conductive plate 72, and one positioning post 713 is correspondingly located at one positioning hole 721.

Further, the heat conducting plate 72 is provided with a concave area 722, the heating plate 73 is arranged in the concave area 722, and the shape of the concave area 722 is the same as that of the heating plate 73, so that the heat conducting plate can be positioned and installed quickly.

In some embodiments, the heating assembly 7 further includes a cover plate 74, the cover plate 74 is connected to the heat conducting plate 72, the heating plate 73 is disposed between the cover plate 74 and the heat conducting plate 72, and the cover plate 74 is used for directly applying external force to the heating plate 73, and the time required for heating the heating plate 73 to a preset test temperature can be reduced. In this embodiment, the cover plate 74 is provided with a plurality of hollow holes for heat dissipation.

In some embodiments, the heating assembly 7 further comprises a temperature sensor (not shown) provided with a temperature measuring hole 723 in the heat conducting plate 72, the temperature sensor being provided in the temperature measuring hole 723 and being for connection with a control board, the temperature sensor being for sensing the temperature of the heat conducting plate 72. It will be appreciated that when the temperature sensor senses that the current temperature of the heat-conductive plate 72 is less than the preset test temperature, the heating plate 73 starts to heat until the heating to the preset test temperature is stopped.

In some embodiments, as shown in fig. 16, the blood gas analysis module 1 further includes a collection board 8 mounted on the substrate, the collection board 8 being provided with connection terminals 81, the connection terminals 81 being for connection with the circuit board 33 of the test card 3, the collection board 8 being for collecting electrical parameters conducted by the circuit board 33. In the present embodiment, the pickup board 8 is mounted to the first substrate 201 and is located below the test card 3.

In some embodiments, as shown in fig. 25, the blood gas analysis module 1 further includes a card pressing mechanism 9, where the card pressing mechanism 9 is used to press the test card 3, so that the test card 3 is tightly connected with the connection terminal 81 on the collection board 8, and the connection looseness between the test card 3 and the connection terminal 81 on the collection board 8 is reduced, which affects data collection. In this embodiment, the test card 3 is provided with the notch 34, the card pressing mechanism 9 includes a card pressing assembly 91 and a telescopic driving member 92, the telescopic driving member 92 is disposed on the base frame 2, the telescopic end of the telescopic driving member 92 is connected with the card pressing assembly 91, the telescopic driving member 92 is used for driving the card pressing assembly 91 to approach or separate from the test card 3, when the telescopic driving member 92 drives the card pressing assembly 91 to approach the test card 3, the card pressing assembly 91 abuts against the notch 34, so that the test card 3 moves towards the collection plate 8, the test card 3 is connected with the connection terminal 81, the test card 3 is tightly fixed on the base frame 2 at this time, and when the telescopic driving member 92 drives the card pressing assembly 91 to separate from the test card 3, the card pressing assembly 91 does not abut against the notch 34 any more, and the test card 3 can be separated from the base frame 2. In this embodiment, the telescopic driving member 92 is disposed on one side of the second substrate 202, the pressing assembly 91 is disposed on the other side of the second substrate 202, and the second substrate 202 is provided with a relief opening 2021 through which the telescopic end of the telescopic driving member 92 passes.

In some embodiments, as shown in fig. 26-28, the card pressing assembly 91 includes a plug member 911 and a guide member 912, the plug member 911 includes a connection block 9111 connected to the telescopic driving member 92 and a plug claw portion 9112 disposed on one side of the connection block 9111, the connection block 9111 is provided with a guide hole 91111, one end of the guide member 912 is connected to the base frame 2, the other end of the guide member 912 is plugged into the guide hole 91111, and the plug claw portion 9112 is used for pressing against the notch 34, so that the telescopic driving member 92 is facilitated to drive the plug member 911 to move directionally under the action of the guide member 912.

In some embodiments, as shown in fig. 29, the latch portion 9112 is provided with an inclined surface 91121, and the inclined surface 91121 is disposed away from the opening 4311 of the latch opening 22; when the telescopic driving member 92 drives the insertion claw portion 9112 to approach the test card 3, the notch 34 abuts against the inclined surface 91121 and slides relatively, so that the test card 3 moves in a direction approaching the collection plate 8. The inclined surface 91121 is provided to facilitate the gradual sliding down of the test card 3 when the insertion claw portion 9112 moves toward the recess 34, so that the circuit board 33 of the test card 3 is connected with the connection terminal 81 of the harvester board.

In some embodiments, the card pressing assembly 91 further includes an elastic member 913, the elastic member 913 is disposed on the guide member 912, two ends of the elastic member 913 respectively abut against the connection block 9111 and the base frame 2, the elastic member 913 provides elastic force to the socket portion, so as to ensure that the socket portion 911 can be pressed when the test card 3 is inserted into the socket portion and the socket portion 911 can be pushed under the action of the elastic member 913 to perform pre-pressing.

In some embodiments, the opposite sides of the test card 3 are provided with notches 34, two of the insertion claw portions 9112 are provided, two insertion claw portions 9112 are spaced apart, and when the telescopic driving member 92 drives the plug member 911 to approach the test card 3, one insertion claw portion 9112 abuts against one notch 34. The number of the elastic members 913 and the number of the guide members 912 are two, and one elastic member 913 is correspondingly arranged on one guide member 912.

In some embodiments, referring to fig. 16 and 30, the blood gas analysis module 1 further includes an abutment member 10 and a latch member 11, wherein the latch member 11 is disposed on the abutment member 10, and the abutment member 10 is disposed in the base frame 2 and partially extends into the insertion slot 22. When the telescopic driving piece 92 drives the card pressing assembly 91 to press the notch 34, the pressing piece 10 is pressed by the test card 3 to press the card ejection piece 11, the card ejection piece 11 is pressed to elastically deform, when the telescopic driving piece 92 drives the card pressing assembly 91 to be away from the test card 3 and the card pressing assembly 91 is separated from the notch 34, the card ejection piece 11 is restored to deform, and the pressing piece 10 is pressed by the card ejection piece 11 to press the test card 3 to move outwards towards the card insertion opening 22. In the present embodiment, the propping member 10 is disposed in the sliding hole 712, and the propping member 10 can slide in the sliding hole 712. The propping piece 10 comprises a propping part 101 and an extension part 102 which are connected, the extension part 102 is arranged in a protruding mode relative to the propping part 101, the extension part 102 extends out of the sliding hole 712, the blood gas analysis module 1 further comprises a third photoelectric sensor 12, the third photoelectric sensor 12 is arranged on the base frame 2, when the third photoelectric sensor 12 detects the extension part 102, and the test card 3 is inserted into a preset position in the card insertion opening 22.

In some embodiments, the latch 11 is a spring or an elastic silica gel block, and the latch 11 is sleeved on the supporting portion 101. Of course, the spring clip 11 may be other, and is not limited to the spring and the elastic silica gel block mentioned herein.

In some embodiments, referring to fig. 27 again, the telescopic driving member 92 is a linear stepping motor, and the press-clamping mechanism 9 further includes a fourth photoelectric sensor 93, where the fourth photoelectric sensor 93 is disposed on the base frame 2, and the fourth photoelectric sensor 93 is used to detect that the telescopic end of the telescopic driving member 92 extends out. When the fourth photoelectric sensor 93 detects the telescopic end of the telescopic driving member 92, the initial position of the card pressing assembly 91 in the retracted state is indicated, so that it can be determined how much angle the linear stepping motor needs to rotate according to the initial position of the card pressing assembly 91 to press the test card 3.

In order to facilitate understanding of the changing process between the card pressing mechanism 9 and the notch 34 of the test card 3, please refer to fig. 31a, 31b and 31c, in which fig. 31a shows that when the test card 3 is inserted into the card insertion slot 22, the test card 3 is in a pre-pressed state under the action of the card pressing component 91 of the card pressing mechanism 9, fig. 31b shows that the card pressing component 91 of the card pressing mechanism 9 approaches the test card under the action of the telescopic driving member 92 and is pressed against the propping member 10 under the action of the inclined surface 91121, and the card ejecting member 11 is pressed to deform, so that the test card 3 is in a pressed state; fig. 31c shows that the card pressing assembly 91 of the card pressing mechanism 9 is far away from the test card 3 under the action of the telescopic driving member 92, the inclined surface 91121 is separated from the notch 34, and the card ejecting member 11 is deformed in a recovery manner and ejects against the test card 3 in a direction far away from the card inserting opening 22, so that a user is facilitated to take out the test card 3.

In some embodiments, as shown in fig. 27 and 32, the blood gas analysis module 1 further includes a negative pressure device 13, where an output end of the negative pressure device 13 is connected to the second connection component 45 of the kit 4, and the negative pressure device 13 is used to provide a negative pressure environment for the test card 3. In this embodiment, the negative pressure device 13 includes a second driving motor 131, a fixing bracket 132, and an air pump 133, where the fixing bracket 132 and the second driving motor 131 are both installed on the base frame 2, the fixing bracket 132 is provided with an installation cylinder 1321 and a fixing base plate 1322 connected with the installation cylinder 1321, the fixing base plate 1322 is installed on the base frame 2, the air pump 133 is installed in the installation cylinder 1321 of the fixing bracket 132, and an output end of the second driving motor 131 is connected with the air pump 133. When the output shaft of the second driving motor 131 is retracted with respect to the fixing bracket 132, the suction pump 133 pumps air from the test card 3 through the second connection assembly 45, thereby providing a negative pressure environment for the test card 3.

In some embodiments, the air pump 133 includes a pump body 1331, a sealing ring 1332, and a piston 1333, wherein the sealing ring 1332 and the piston 1333 are both accommodated in the pump body 1331, the sealing ring 1332 is mounted on the piston 1333, the sealing ring 1332 abuts against an inner wall surface of the pump body 1331, the piston 1333 is connected with an output shaft of the second driving motor 131, and when the output shaft of the second driving motor 131 extends or retracts relative to the pump body 1331, the piston 1333 moves synchronously with the output shaft of the second driving motor 131. One end of the pump body 1331 is provided with a pump body head 13311, the pump body head 13311 penetrates out of the mounting cylinder 1321, the pump body head 13311 is used for being connected to the negative pressure pipeline 318 of the test card 3 through the second connecting component 45 of the kit 4, so that the piston 1333 can draw air in the test card 3 when being far away from the pump body head 13311 under the action of the output shaft of the second driving motor 131, and a negative pressure environment is provided. The pump body head 13311 may be directly connected to the second connecting component 45, or may be connected by providing an air extraction pipeline. In this embodiment, the second driving motor 131 is a linear motor, and the pump body head 13311 is connected to the second connection assembly 45 of the kit 4 through an air suction pipe.

In some embodiments, the negative pressure device 13 further includes a sealing sleeve 134, the sealing sleeve 134 is sleeved on the pump body 1331, the sealing sleeve 134 is mounted on the fixing bracket 132, and the sealing sleeve 134 is used for sealing between the mounting cylinder 1321 and the suction pump 133. In this embodiment, the sealing sleeve 134 is made of a silicone material, however, the sealing sleeve 134 can be made of other materials, so long as it can seal with the mounting cylinder 1321.

In some embodiments, as shown in fig. 27, the blood gas analysis module 1 further includes a fifth photoelectric sensor 14, the fifth photoelectric sensor 14 is mounted on the base frame 2, and the fifth photoelectric sensor 14 is configured to detect an output shaft of the second driving motor 131. It is understood that the output shaft of the second driving motor 131 includes a first end and a second end, and the first end is connected to the suction pump 133. When the second driving motor 131 drives the air pump 133 to pump air, the first end gradually retracts into the body of the second driving motor 131, and the second end gradually extends out of the body of the second driving motor 131. When the fifth photosensor 14 detects the second end, the position where the output shaft of the second driving motor 131 is currently located at this time may be determined as an origin so that the second driving motor 131 moves to an initial position according to a preset travel distance. In the actual use process, when the blood gas analysis module 1 starts to work, the output shaft of the second driving motor 131 moves to the initial position, and when the negative pressure environment is required to be provided for the test card 3, the output end of the second driving motor 131 pulls the piston 1333 to move a preset distance towards the direction extending out of the pump body 1331.

The working principle of the blood gas analysis module 1 is as follows:

(1) The second connecting component 45 of the kit 4 is connected with the negative pressure device 13, the rotating piece 432 of the control valve 43 is connected with the rotating motor 51 of the driving mechanism 5 through the clamping block 53, and the control valve 43 is in a third working state, namely in a closed state;

(2) The test card 3 is connected with a container filled with liquid to be tested outside, when the test card 3 is inserted into the card insertion opening 22, the insertion part is in a retracted state relative to the test card 3, the test card 3 pushes down the insertion part 911, under the action of the elastic part 913, the two ends of the insertion part 911 press the notch 34 of the test card 3, at this time, the pre-pressing of the test card 3 is realized, and the convex propping part 10 is also pushed down by the test card 3.

(3) The plug 911 is driven by the telescopic driving member 92 to move forward, and under the action of the fourth photoelectric sensor 93, the plug 911 starts from a predetermined initial position and advances by a predetermined elongation, at this time, the inclined surface 91121 of the plug 911 presses the test card 3 downward, at this time, the test card 3 is pressed into the card slot 22 of the base frame 2, the circuit board 33 is connected with the collecting board 8, and the sealing head 462 of the sealing block 46 abuts against the calibration pipeline 311 and the negative pressure pipeline 318 of the test card 3. The calibration pipeline 311 of the test card 3 is communicated with the first contact pin 442 of the kit 4, the negative pressure pipeline 318 and the second contact pin 452, and the outer sides of the first contact pin 442 and the second contact pin 452 are sealed under the action of the sealing block 46.

(4) The first driving motor 61 in the shifting fork mechanism 6 drives the first shifting lever 623 and the second shifting lever 624 to rotate, and the first shifting lever 623 pushes the switch valve 32 to move the switch valve 32 to the first position relative to the card main body 31 so as to block the calibration pipeline 311 and the test pipeline 312.

(5) The rotary motor 51 of the driving mechanism 5 drives the rotary member 432 of the control valve 43 to rotate, so that the rotary member 432 rotates to the first working state, and at this time, the reagent pack 42 is communicated with the calibration pipeline 311 of the test card 3.

(6) The second driving motor 131 in the negative pressure device 13 drives the piston 1333 in the air pump 133 to pull back, so that the negative pressure pipeline 318 generates negative pressure, and the calibration liquid flows into the calibration pipeline 311 and the reaction pipeline 313 from the reagent pack 42. After the calibration is completed, the rotary member 432 of the control valve 43 is rotated to the second operating state, so that the calibration liquid pipeline is communicated with air, and the suction pump 133 continues to generate negative pressure, so that air enters the calibration pipeline 311 and the reaction pipeline 313 from the reagent kit 4, and the calibration liquid is pumped into the waste liquid tank 317. At this time, the rotary member 432 is rotated to the third operating state, i.e., the control valve 43 is closed.

(7) The first driving motor 61 in the shifting fork mechanism 6 drives the second shifting rod 624 to push the switch valve 32, so that the switch valve 32 moves inwards relative to the card main body 31 to a second position, the test pipeline 312 is opened, the air pump 133 works to generate negative pressure, and the test liquid flows into the test pipeline 312 and the reaction pipeline 313 from the external container for testing. The test data are transferred from the circuit board 33 to the acquisition board 8.

(8) After the test is completed, the first driving motor 61 of the shifting fork mechanism 6 drives the first shifting rod 623 to rotate, so that the switch valve 32 moves outwards relative to the card main body 31 to block the test pipeline 312, i.e. the switch valve is switched back to the first position again, thereby ensuring that the test liquid cannot flow out, and the calibration liquid cannot flow out due to the fact that the outlet of the waste liquid tank 317 is arranged at the top of the cavity, so that pollution is avoided.

(9) The telescopic driving piece 92 of the card pressing mechanism 9 drives the plug-in piece 911 to retract, so that the plug-in claw 9112 of the plug-in piece 911 is separated from the notch 34 of the test card 3, and the propping piece 10 pushes the test card 3 to move upwards to a card withdrawing state under the action of the card ejecting piece 11. At this time, the entire operation is completed, and all the drives are reset.

It can be understood that the test card 3 is pushed to the card withdrawing state by the pushing member 10, and the test liquid cannot flow into the calibration pipeline 311 due to the blocking of the switch valve 32 because the switch valve 32 is at the first position, so as to avoid the occurrence of liquid leakage after the test card 3 is separated from the kit 4.

The blood gas analysis module 1 provided by the embodiment of the application comprises a base frame 2, a test card 3, a reagent kit 4, a driving mechanism 5 and a shifting fork assembly 62, wherein the base frame 2 is provided with a storage cavity 21 and a bayonet 22, and the storage cavity 21 is used for accommodating the reagent kit 4; the test card 3 is inserted into the card insertion opening 22, the test card 3 comprises a card main body 31, a switch valve 32 and a sealing film 37 arranged on the card main body 31, the card main body 31 is provided with a groove 314 for communicating a calibration pipeline 311 and a test pipeline 312, the switch valve 32 is movably arranged on the groove 314, the switch valve 32 is configured to block the joint of the calibration pipeline 311 and the test pipeline 312 when being in a first position, and the calibration pipeline 311 is communicated with the test pipeline 312 when being in a second position; the kit 4 comprises a reagent shell 41, a reagent pack 42, a control valve 43 and a first connecting component 44, wherein the reagent pack 42 and the control valve 43 are contained in the reagent shell 41, the control valve 43 is partially exposed out of the reagent shell 41, the first connecting component 44 is connected with the control valve 43 and a calibration pipeline 311, a liquid inlet end of the control valve 43 is connected with the reagent pack 42, and the control valve 43 is used for controlling the reagent pack 42 to be communicated with or cut off from the calibration pipeline 311; the driving mechanism 5 is mounted on the base frame 2 and connected with the control valve 43, and the driving mechanism 5 is used for switching the working state of the control valve 43; the shifting fork mechanism 6 comprises a first driving motor 61 and a shifting fork assembly 62, the first driving motor 61 is installed on the base frame 2, the shifting fork assembly 62 is installed on an output shaft of the first driving motor 61, and the first driving motor 61 is used for driving the shifting fork assembly 62 to rotate so as to shift the switching valve 32, so that the switching valve 32 is switched between a first position and a second position. Through the blood gas analysis module 1 of above-mentioned structure, the shift fork subassembly 62 can stir the ooff valve 32 in the test card 3 to realize calibration pipeline 311 and test pipeline 312 intercommunication or cut off, compare in pressing the elastic membrane of test card 3 and make it warp in order to isolate the mode of calibration pipeline 311 and test pipeline 312, avoided the risk that the damage appears in test card 3, be favorable to improving the stability and the security performance of blood gas analysis module 1.

As shown in fig. 33, a blood gas analyzer 20 according to another embodiment of the present application includes the blood gas analysis module 1 of the above embodiment. The blood gas analyzer 20 further comprises a housing 15, a main board 16, a control board 17 and a display screen 18, wherein the main board 16 and the control board 17 are all accommodated in the housing 15, the display screen 18 is installed on the housing 15, the main board 16 is connected with the acquisition board 8, the first driving motor 61, the second driving motor 131, the rotating motor 51 and the telescopic driving piece 92 are all connected with the control board, and the control board 17 is used for controlling the first driving motor 61, the second driving motor 131, the rotating motor 51 and the telescopic driving piece 92 to act. The main board 16 is used for outputting display signals to the display screen 18 after calculation of the electrical signal algorithm obtained from the acquisition board 8, and the display screen 18 displays information obtained by measurement.

When the blood gas analyzer is used for detecting blood of a human body, the blood gas analyzer electrochemically measures parameters such as PH (PH value), pCO2 (partial pressure of carbon dioxide), pO2 (partial pressure of oxygen), na+ (sodium ion concentration), cl- (chloride ion concentration), K+ (potassium ion concentration), ca++ (calcium ion concentration) and Hct (hematocrit), lac (lactic acid), glu (glucose) in the blood of the human body, and the measured PH value and pCO are used for measuring the blood gas of the human body ₂ 、pO ₂ 、Na ⁺ 、K ⁺ 、Cl ^- 、Ca ²⁺ Parameters Hct, glu, lac, etc. are calculated and the final result is displayed on the display 18.

The foregoing description is only of embodiments of the present invention, and is not intended to limit the scope of the invention, and all equivalent structures or equivalent processes using the descriptions and the drawings of the present invention or directly or indirectly applied to other related technical fields are included in the scope of the present invention.

Claims

1. A blood gas analysis module, comprising:

the pedestal is provided with a containing cavity and an inserting port, and the containing cavity is used for containing the reagent box;

the test card is inserted into the card insertion port and comprises a card main body, a switch valve and a sealing film, wherein the sealing film is arranged on the card main body;

the kit comprises a reagent shell, a reagent pack, a control valve and a first connecting component, wherein the reagent pack and the control valve are contained in the reagent shell, the control valve part is exposed out of the reagent shell, the first connecting component is connected with the control valve and the calibration pipeline, the liquid inlet end of the control valve is connected with the reagent pack, and the control valve is used for controlling the reagent pack to be communicated with or cut off from the calibration pipeline;

The driving mechanism is arranged on the base frame and connected with the control valve, and is used for switching the working state of the control valve;

the shifting fork mechanism comprises a first driving motor and a shifting fork assembly, wherein the first driving motor is installed on the base frame, the shifting fork assembly is installed on an output shaft of the first driving motor, and the first driving motor is used for driving the shifting fork assembly to rotate so as to stir the switching valve, so that the switching valve is switched between a first position and a second position.

2. The blood gas analysis module according to claim 1, wherein the control valve comprises a valve housing provided with an opening through which the rotary member protrudes, a rotary member rotatably provided to the valve housing, the valve housing provided with a liquid inlet passage connected to the reagent pack and an output end for connection to the calibration line of the test card, a plurality of sealing members provided between the valve housing and the rotary member, the rotary member provided with a recess, a first communication hole, and a second communication hole provided on both sides of the recess, the shielding member provided to the rotary member and shielding the recess, the first communication hole connected to the output end of the valve housing, and a sealing member surrounding the output end of the valve housing.

The rotating member is configured such that the liquid inlet passage communicates with the output end of the valve housing through the recess portion when in a first operation state, the output end of the valve housing is supplied with air from the second communication hole through the first communication hole to be supplied to the calibration pipe when in a second operation state, and the output end of the valve housing is in a blocking state under the action of the plurality of sealing members when in a third operation state.

3. The blood gas analysis module of claim 1, wherein the driving mechanism comprises a rotating motor, a first fixed block and a clamping block, the first fixed block is connected with the rotating motor, the first fixed block is provided with an avoidance hole for an output shaft of the rotating motor to extend out, the output shaft of the rotating motor is connected with the clamping block, and the clamping block is used for being clamped with the control valve.

4. The blood gas analysis module of claim 3, wherein the clamping block comprises a first protrusion and a clamping portion, the first protrusion is disposed on one side of the clamping portion, the clamping portion is provided with a clamping groove for clamping with the control valve, and the first protrusion is used for being connected with an output shaft of the rotating motor.

5. The blood gas analysis module of claim 4, wherein the drive mechanism further comprises a first photoelectric sensor mounted to the first fixed block, the clamping block further comprises a second protrusion disposed on the same side of the clamping portion at an interval from the first protrusion, and the first photoelectric sensor is configured to detect a position of the second protrusion.

6. The blood gas analysis module of claim 1, wherein the fork assembly comprises a connecting piece, an elastic piece, a first deflector rod and a second deflector rod, the connecting piece is sleeved on an output shaft of the first driving motor, the first deflector rod and the second deflector rod are rotatably installed on the connecting piece and are arranged at intervals, and the elastic piece is connected with the first deflector rod and the second deflector rod;

when the first driving motor drives the connecting piece to rotate along a first direction, the first deflector rod can stir the switch valve to the first position, and when the first driving motor drives the connecting piece to rotate along a second direction, the second deflector rod can stir the switch valve to the second position, wherein the first direction and the second direction are opposite.

7. The blood gas analysis module of claim 6, wherein the fork mechanism further comprises a second fixing block and a second photoelectric sensor, the second fixing block is connected with the base frame and the first driving motor, a first protrusion is arranged on the second fixing block, a second protrusion is arranged on the connecting piece, when the first driving motor drives the connecting piece to rotate, and the first protrusion abuts against the second protrusion, the first poking rod pokes the switch valve to the first position, the second photoelectric sensor is mounted on the second fixing block, and the second photoelectric sensor is used for detecting whether the second protrusion reaches a preset position.

8. The blood gas analysis module of claim 1, further comprising a card pressing mechanism and a collection plate arranged on the base frame, wherein the card pressing mechanism comprises a card pressing assembly and a telescopic driving piece, the telescopic driving piece is arranged on the base frame, a telescopic end of the telescopic driving piece is connected with the card pressing assembly, the telescopic driving piece is used for driving the card pressing assembly to be close to or far away from the test card, the test card is provided with a notch,

When the telescopic driving piece drives the card pressing assembly to be close to the test card, the card pressing assembly presses the notch, so that the test card moves towards the collection, and the test card is connected with the connection terminal of the collection board.

9. The blood gas analysis module of claim 8, wherein the clamping assembly comprises a plug-in connector and a guide member, the plug-in connector comprises a connecting block connected with the telescopic driving member and a claw portion arranged on one side of the connecting block, the connecting block is provided with a guide hole, one end of the guide member is connected with the base frame, the other end of the guide member is inserted into the guide hole, the claw portion is provided with an inclined surface, and the claw portion is used for propping against the notch.

10. A blood gas analyzer comprising a blood gas analysis module according to any one of claims 1-9.