CN117284622B - Anti-tumor clinical mass spectrometry detection kit - Google Patents

Anti-tumor clinical mass spectrometry detection kit Download PDF

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Publication number
CN117284622B
CN117284622B CN202311576658.2A CN202311576658A CN117284622B CN 117284622 B CN117284622 B CN 117284622B CN 202311576658 A CN202311576658 A CN 202311576658A CN 117284622 B CN117284622 B CN 117284622B
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CN
China
Prior art keywords
sides
groups
cooling
fixing
pieces
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Active
Application number
CN202311576658.2A
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Chinese (zh)
Other versions
CN117284622A (en
Inventor
车团结
徐进章
李雅娜
陈一戎
张鑫衍
王志平
杨立
王全立
郭柏鸿
焉丽波
阚莹
张璀
刘妮妮
于琪
张轶博
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yantai Zhigong Biomedical Technology Co ltd
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Yantai Zhigong Biomedical Technology Co ltd
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Priority to CN202311576658.2A priority Critical patent/CN117284622B/en
Publication of CN117284622A publication Critical patent/CN117284622A/en
Application granted granted Critical
Publication of CN117284622B publication Critical patent/CN117284622B/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • B65D25/10Devices to locate articles in containers
    • B65D25/101Springs, elastic lips, or other resilient elements to locate the articles by pressure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/02Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
    • B65D81/05Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/18Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants

Abstract

The invention relates to the technical field related to a kit, in particular to an anti-tumor clinical mass spectrometry detection kit, which comprises a kit body, wherein a rubber frame is fixedly connected to the outer side edge of the kit body, a sealing cover is movably clamped at the inner side of the rubber frame, a cooling part is connected to the lower part of the inner side of the kit body through a clamping part, fixing frames are fixedly connected to the upper surfaces of two sides of the cooling part, a plurality of groups of support assemblies are arranged on the outer sides of the fixing frames, a plurality of groups of clamping pipe fittings are arranged on the inner sides of the support assemblies, and a sealing part is arranged on the upper side of the inner side of the kit body.

Description

Anti-tumor clinical mass spectrometry detection kit
Technical Field
The invention relates to the technical field of kits, and particularly provides an anti-tumor clinical mass spectrometry detection kit.
Background
The anti-tumor clinical mass spectrometry detection kit is a kit for mass spectrometry analysis of tumor related molecules. Mass spectrometry is a technique for analyzing molecular structure and composition in a sample. These kits contain reagents and equipment for sample pretreatment and analysis, and standard substances for calibration and calibration of the instrument, and the tumor detection has a shelf life, i.e. is kept until a certain period after the report is sent, and the detection result remains valid. This is because the laboratory may only detect at the beginning of the report, make a decision and incorporate it into the report, and have the detection and report validity time limit coexist. The shelf life of the tumor detection sample is 48 hours, wherein the storage is carried out for 2 hours, the storage is carried out for 86 hours at 4-10 ℃, and the report is not more than 5 days after being sent, the use of the existing kit can be ensured by external refrigeration measures, the hole site is customized according to the diameter of the reagent tube on the inner side, and a fixed component is not assembled in the kit in the transportation process, so that the reagent tube is easy to crack because of larger space shaking in the inner side, and therefore, the problems are improved.
Disclosure of Invention
The invention aims to solve the problems in the background technology and provides an anti-tumor clinical mass spectrometry detection kit.
In order to achieve the above purpose, the invention provides an anti-tumor clinical mass spectrometry detection kit, which comprises a box body, wherein a rubber frame is fixedly connected to the outer edge of the box body, a sealing cover is movably clamped on the inner side of the rubber frame, a cooling piece is connected to the lower part of the box body through a clamping piece, fixing frames are fixedly connected to the upper surfaces of two sides of the cooling piece, a plurality of groups of support assemblies are arranged on the outer sides of the two groups of fixing frames, a plurality of groups of clamping pipe fittings are arranged on the inner sides of the support assemblies, and a sealing piece is arranged above the inner side of the box body.
Preferably, the buckle piece comprises fixing rods below the inner parts of two sides of the box body, rubber sleeves are movably sleeved on the upper parts of the outer sides of the fixing rods, and the two rubber sleeves are all arranged at the bottom of the cooling piece.
Preferably, the cooling piece comprises a cooling bin which is fixedly installed on the top ends of the two rubber sleeves together, control pieces are arranged at the bottoms of two sides of the cooling bin and at one end far away from the fixing rod, and a plurality of groups of air outlets are formed in four sides of the inner side of the cooling bin.
Preferably, the control piece comprises fixing seats fixedly installed at the bottoms of two sides of the cooling bin and far away from one end of the fixing rod, a storage cavity is formed in the inner side of each fixing seat, coolers are fixedly installed in the inner sides of the storage cavities, and the output ends of the coolers correspond to the inside of the cooling bin.
Preferably, the plurality of groups of the frame support assemblies comprise U-shaped frames which are clamped on the outer sides of the two fixing frames together, a plurality of groups of circulation ports are formed in the inner sides of two ends of each U-shaped frame, a plurality of groups of clamping pipe fittings are arranged on the inner sides of the U-shaped frames, and anti-slip pads are arranged on the surfaces of the U-shaped frames.
Preferably, the multiunit card pipe fitting is including the frame of equal fixed mounting in U-shaped frame inboard, the inside equal fixed mounting of frame both sides has the fixed plate, two the multiunit knot piece is all installed to the fixed plate inner wall, and is relative two fixedly connected with bullet rope between the knot piece, the bullet rope outside is provided with a plurality of laminating pieces, and is a plurality of laminating pieces are including installing the arc piece at bullet rope outside both ends respectively, two sets of arc piece top installs the arc seat jointly.
Preferably, the sealing piece comprises a fixing frame movably clamped above the inner side of the box body, the inner side of the fixing frame is provided with a supporting frame along the horizontal direction at equal distance, the edges of two sides of the supporting frame are fixedly provided with vertical rods, the outer sides of the vertical rods are sleeved with springs, and the outer sides of the vertical rods are provided with buffer pieces.
Preferably, the buffer piece comprises fixing blocks which slide on the outer sides of the two vertical rods at the same position respectively, and laminating cotton is commonly installed between the two fixing blocks.
Compared with the prior art, the invention has the following beneficial effects:
the cooler and the cooling bin are arranged below the inner side of the box body to cool and store the reagent tube, so that samples cannot be lost in the transportation process, the plurality of groups of U-shaped frames and the frames are arranged inside the cooling bin to store the reagent tube, when the reagent tube is placed inside the corresponding frames, the elastic ropes corresponding to the outer sides can be wrapped and rubbed on the surface of the reagent tube along with the extrusion of the reagent tube, the reagent tube is attached through the arc-shaped sheets on the outer sides, the reagent tube cannot shake, the elastic ropes can be wrapped and rubbed relatively, more reagent tubes can be adapted to be used, in order to ensure that the leakage cannot occur in the transportation process, the fixing frames can be clamped above the inner side of the box body after the reagent tube is fixed, corresponding attaching cottons can be pressed along with the elasticity of the springs, attached to the top ends of the reagent tube, the vacant space above the inner side of the reagent tube is filled, the reagent tube cannot shake, and the problem that the space filling causes breakage and leakage can be avoided.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present invention;
FIG. 2 is a schematic view showing the inner structure of the case of the present invention;
FIG. 3 is a schematic view of the closure of the present invention;
FIG. 4 is a schematic view of the cooling chamber structure of the present invention;
FIG. 5 is a schematic view of a portion of the structural connection between the cooling cartridge and the frame of the present invention;
FIG. 6 is a schematic view of the internal structure of the frame of the present invention;
FIG. 7 is an enlarged view of FIG. 6A in accordance with the present invention;
fig. 8 is a schematic diagram of a connection structure between a fixing frame and a U-shaped frame according to the present invention.
In the figure: 1. a case body; 2. sealing cover; 3. a rubber frame; 4. a fixing seat; 5. a cooling bin; 6. a fixed rod; 7. a rubber sleeve; 8. a storage cavity; 9. an air outlet; 10. a flow port; 11. an anti-slip pad; 12. a frame; 13. a fixing frame; 14. a U-shaped frame; 15. a support frame; 16. a fixed frame; 17. attaching cotton; 18. a spring; 19. a fixed block; 20. a vertical rod; 21. a cooler; 22. a fixing plate; 23. a buckling block; 24. an arc-shaped sheet; 25. a rope is sprung; 26. arc-shaped base.
Detailed Description
In order that the above-recited objects, features and advantages of the present invention will be more clearly understood, a more particular description of the invention will be rendered by reference to the appended drawings and appended detailed description.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, however, the present invention may be practiced in other ways than those described herein, and therefore the present invention is not limited to the specific embodiments disclosed below.
The anti-tumor clinical mass spectrometry detection kit comprises a kit body 1, wherein the edge of the outer side of the kit body 1 is fixedly connected with a rubber frame 3, a sealing cover 2 is movably clamped on the inner side of the rubber frame 3, cooling pieces are connected below the inner side of the kit body 1 through fastening pieces, fixing frames 13 are fixedly connected to the upper surfaces of two sides of the cooling pieces, a plurality of groups of support assemblies are arranged on the outer sides of the two groups of fixing frames 13, a plurality of groups of clamping pipe fittings are arranged on the inner sides of the plurality of groups of support assemblies, and a sealing piece is arranged above the inner side of the kit body 1.
The buckle spare includes the dead lever 6 of the inside below in box body 1 both sides, rubber sleeve 7 has been cup jointed in the activity of two dead lever 6 outside top, dead lever 6 and rubber sleeve 7 can movable clamping, make its cooling part install in the inboard below of box body 1, two rubber sleeves 7 are all installed in the cooling part bottom, the cooling part is including common fixed mounting cooling storehouse 5 on two rubber sleeve 7 tops, cooling storehouse 5 both sides bottom just keep away from the one end of dead lever 6 all is provided with the control, multiunit air outlet 9 has all been seted up on cooling storehouse 5 inboard four sides, can evenly distribute the cold air flow at the box body 1 inboard through multiunit air outlet 9.
The control includes fixed mounting in cooling storehouse 5 both sides bottom and keeps away from fixing base 4 of dead lever 6 one end, and two thing chambeies 8 have been seted up to the fixing base 4 inboard, and two are put thing chambeies 8 inboard and are all fixed mounting has cooler 21, under the connection of cooler 21, can carry cooling air current to cooling storehouse 5 inside, then come to carry out the low temperature to the reagent pipe of box body 1 inboard and preserve, correspond the cooler 21 output and all extend to cooling storehouse 5 inside, and cooler 21 is general cooling device among the prior art, uses including low temperature constant temperature circulator.
The multiunit frame props subassembly including all jointly the cartridge in the U-shaped frame 14 in two mount 13 outsides, multiunit circulation mouth 10 has all been seted up to U-shaped frame 14 both ends inboard, circulation mouth 10 that sets up in U-shaped frame 14 inboard can promote U-shaped frame 14 both sides to circulate faster, multiunit card pipe fitting all sets up in U-shaped frame 14 inboard, U-shaped frame 14 surface is provided with slipmat 11, slipmat 11 that sets up at U-shaped frame 14 surface can contradict reagent tube bottom, thereby avoid letting reagent tube lower extreme excessively rock, multiunit card pipe fitting includes frame 12 of equal fixed mounting in U-shaped frame 14 inboard, frame 12 both sides inside is fixed mounting has fixed plate 22, multiunit buckling pieces 23 are all installed to two fixed plate 22 inner wall, fixedly connected with bullet rope 25 between two relative buckling pieces 23, all be provided with bullet rope 25 between two buckling pieces 23 of central symmetry, the arc piece 24 that bullet rope 25 can promote the outside can adapt to laminating at the surface of reagent tube, increase the frictional resistance of bullet rope 25 self, then let bullet rope 25 card pipe 25 install the reagent piece, a plurality of pieces are installed to the arc piece 24 when the arc piece is installed to the both ends of two and the arc piece is installed to the arc piece 24 and the arc piece is installed to the both ends and the arc piece is put into the arc base 24 and the problem is difficult to the top is put into to the arc base to the both sides when two the arc piece 24 is installed to the both sides.
The sealing piece comprises a fixing frame 16 movably clamped above the inner side of the box body 1, supporting frames 15 are mounted on the inner side of the fixing frame 16 at equal intervals along the horizontal direction, PE plastic materials are adopted for the fixing frame 16 and movably clamped with the inner wall of the box body 1, after reagent tubes are clamped, the fixing frame 16 can be clamped above the inner side of the box body 1, vertical rods 20 are fixedly mounted on edges of two sides of a plurality of groups of supporting frames 15, springs 18 are sleeved outside the two vertical rods 20 at the same position, buffer pieces are arranged outside the two vertical rods 20 at the same position, each buffer piece comprises a fixing block 19 respectively sliding outside the two vertical rods 20 at the same position, bonding cotton 17 is jointly mounted between the two fixing blocks 19, the supporting frames 15 can be clamped with the fixing frame 16, the bonding cotton 17 can slide outside the corresponding two vertical rods 20 under the elastic supporting pressure of the springs 18 until the surfaces are contacted with the top ends of a plurality of reagent tubes, and the top ends of the reagent tubes are sealed.
Working principle: the user can put into the reagent pipe that corresponds the frame 12 inboard, the bullet rope 25 of corresponding outside can be wrapped up in the surface of rubbing at the reagent pipe along with the extrusion of reagent pipe, the arc piece 24 through the outside comes with reagent pipe surface reinforcing frictional resistance, thereby let the reagent pipe can not take place to rock, and the relative wrapping up of bullet rope 25 is rubbed, can adapt to more reagent pipes and use, and can cool off the reagent pipe at the cooler 21 of box body 1 inboard below and cooling bin 5, thereby can not let the sample take place the loss in the transportation after gathering, in order to ensure can not leak in the transportation, can be with fixed frame 16 cartridge to box body 1 inboard top after fixing the reagent pipe, the laminating cotton 17 of correspondence can be along with the elasticity of spring 18 is supported and is pressed, attached on the top of reagent pipe, thereby let the reagent pipe top empty space fill, make the reagent pipe can not produce and rock, the problem that the space filling leads to breaking and leaking appears is avoided appearing.
The foregoing has shown and described the basic principles, principal features and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present invention, and various changes and modifications may be made therein without departing from the spirit and scope of the invention, which is defined by the appended claims. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (1)

1. An anti-tumor clinical mass spectrometry detection kit comprises a kit body (1), and is characterized in that: the novel cooling box comprises a box body (1), wherein a rubber frame (3) is fixedly connected to the outer side edge of the box body (1), a sealing cover (2) is movably clamped on the inner side of the rubber frame (3), cooling pieces are connected to the lower portion of the inner side of the box body (1) through clamping pieces, fixing frames (13) are fixedly connected to the upper surfaces of the two sides of the cooling pieces, a plurality of groups of support assemblies are arranged on the outer sides of the two groups of fixing frames (13), a plurality of groups of clamping pipe fittings are arranged on the inner sides of the support assemblies, and sealing pieces are arranged above the inner sides of the box body (1);
the plurality of groups of frame support components comprise U-shaped frames (14) which are clamped on the outer sides of the two fixing frames (13) together, a plurality of groups of circulation ports (10) are formed in the inner sides of two ends of each U-shaped frame (14), a plurality of groups of clamping pipe fittings are arranged on the inner sides of the U-shaped frames (14), and anti-slip pads (11) are arranged on the surfaces of the U-shaped frames (14);
the clamping pipe fittings comprise frames (12) which are fixedly arranged on the inner sides of the U-shaped frames (14), fixing plates (22) are fixedly arranged in the two sides of each frame (12), a plurality of groups of buckling blocks (23) are arranged on the inner walls of the two fixing plates (22), elastic ropes (25) are fixedly connected between the corresponding buckling blocks (23), a plurality of attaching pieces are arranged on the outer sides of the elastic ropes (25), each attaching piece comprises arc-shaped pieces (24) which are respectively arranged on the two ends of the outer sides of the elastic ropes (25), and arc-shaped seats (26) are commonly arranged at the tops of the two groups of arc-shaped pieces (24);
the sealing piece comprises a fixed frame (16) movably clamped above the inner side of the box body (1), supporting frames (15) are arranged on the inner side of the fixed frame (16) at equal intervals along the horizontal direction, vertical rods (20) are fixedly arranged on the edges of two sides of a plurality of groups of the supporting frames (15), springs (18) are sleeved on the outer sides of the two vertical rods (20) at the same position, and buffer pieces are arranged on the outer sides of the two vertical rods (20) at the same position;
the buffer piece comprises fixed blocks (19) which slide outside two vertical rods (20) at the same position respectively, and laminating cotton (17) is commonly arranged between the two fixed blocks (19);
the clamping piece comprises fixing rods (6) below the inner parts of the two sides of the box body (1), rubber sleeves (7) are movably sleeved above the outer sides of the two fixing rods (6), and the two rubber sleeves (7) are arranged at the bottom of the cooling piece;
the cooling piece comprises cooling bins (5) which are fixedly installed at the top ends of two rubber sleeves (7), control pieces are arranged at the bottoms of two sides of the cooling bins (5) and at one ends far away from the fixed rods (6), and a plurality of groups of air outlets (9) are formed in four sides of the inner side of the cooling bins (5);
the control piece comprises fixing seats (4) fixedly installed at the bottoms of two sides of the cooling bin (5) and far away from one end of the fixing rod (6), a storage cavity (8) is formed in the inner side of each fixing seat (4), coolers (21) are fixedly installed in the inner sides of the storage cavities (8), and the output ends of the coolers (21) are correspondingly extended to the inside of the cooling bin (5).
CN202311576658.2A 2023-11-24 2023-11-24 Anti-tumor clinical mass spectrometry detection kit Active CN117284622B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311576658.2A CN117284622B (en) 2023-11-24 2023-11-24 Anti-tumor clinical mass spectrometry detection kit

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Application Number Priority Date Filing Date Title
CN202311576658.2A CN117284622B (en) 2023-11-24 2023-11-24 Anti-tumor clinical mass spectrometry detection kit

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CN117284622A CN117284622A (en) 2023-12-26
CN117284622B true CN117284622B (en) 2024-01-26

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017219323A1 (en) * 2016-06-23 2017-12-28 巴罗克(济南)生物技术有限公司 Reagent tube
KR20200058953A (en) * 2018-11-20 2020-05-28 에이비메디컬 주식회사 spray nozzle of reagent for blood collection tube
CN211140117U (en) * 2019-11-29 2020-07-31 漯河市宏安检测评价服务有限公司 Environmental test sample storage device
CN111621404A (en) * 2020-06-16 2020-09-04 王晓伟 Stable alpha-amylase detection kit
CN216970647U (en) * 2021-10-09 2022-07-15 广州市凯诺生物科技有限公司 Germ detection kit with liquid cooling module
CN218318187U (en) * 2022-11-03 2023-01-17 江苏科来雅生物医药有限公司 Enzyme linked immunosorbent assay kit

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017219323A1 (en) * 2016-06-23 2017-12-28 巴罗克(济南)生物技术有限公司 Reagent tube
KR20200058953A (en) * 2018-11-20 2020-05-28 에이비메디컬 주식회사 spray nozzle of reagent for blood collection tube
CN211140117U (en) * 2019-11-29 2020-07-31 漯河市宏安检测评价服务有限公司 Environmental test sample storage device
CN111621404A (en) * 2020-06-16 2020-09-04 王晓伟 Stable alpha-amylase detection kit
CN216970647U (en) * 2021-10-09 2022-07-15 广州市凯诺生物科技有限公司 Germ detection kit with liquid cooling module
CN218318187U (en) * 2022-11-03 2023-01-17 江苏科来雅生物医药有限公司 Enzyme linked immunosorbent assay kit

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