CN117192136A - Sample analyzer and sample detection flow thereof - Google Patents

Abstract

The invention discloses a sample analyzer and a sample detection flow thereof, wherein the sample analyzer comprises: the automatic sample feeding assembly conveys the sample tube to a sampling position along a sample feeding track in the X direction; the transfer assembly comprises a transfer seat, and moves between a transfer position and a conventional sampling position along a transfer path, wherein the transfer position is right above the sampling position, and the conventional sampling position deviates from the transfer position in both directions X, Y; the sampling assembly comprises a sampling needle which moves along a sample conveying path, and a plurality of sample dividing positions are arranged on the sample conveying path; the detection assembly comprises a plurality of reaction measurement pools, each reaction measurement pool is positioned under one sample dividing position, the sample tube on the middle rotary seat of the conventional sampling position is sampled and then moves along the sample conveying path, the collected sample to be detected is injected into the reaction measurement pool below at each sample dividing position for detection, the whole layout of the detection assembly is flexible and reasonable, and each assembly operates in a coordinated manner, so that the sample detection flow can be effectively accelerated, and the detection efficiency can be improved.

Description

Sample analyzer and sample detection flow thereof

Technical Field

The present invention relates to the field of sample detection technology, and in particular, to a sample analyzer and a sample detection flow thereof.

Background

The sample analyzer is the most commonly used blood cell analyzer, which performs statistical analysis on various cells in a blood sample, such as red blood cells, white blood cells, platelets, hemoglobin, and the like, by means of reagents, and provides a basis for diagnosis and treatment of diseases.

In general, a movable transfer component is arranged in a sample analyzer, a sample to be detected is moved to a sampling position through the transfer component for puncture sampling, and collected sample liquid is injected into a reaction tank of a detection component to be mixed and reacted with a corresponding reagent, so that corresponding detection data is output. However, the transfer assembly of the existing sample analyzer only moves forward and backward to transfer the sample to be tested, which limits the arrangement of other assemblies to a certain extent, such as the sampling assembly and the detection assembly only can be arranged at the rear of the transfer assembly, so that the overall layout of the sample analyzer is not flexible and reasonable, the overall size of the sample analyzer is huge, and the sample detection process is long in time consumption and low in efficiency.

Disclosure of Invention

In view of the above, a sample analyzer and a sample detection flow thereof are provided that can effectively solve the above-mentioned technical problems.

The present invention provides a sample analyzer comprising: the automatic sample feeding assembly is used for conveying a sample tube containing a sample to be tested to a sampling position of a sample analyzer along a sample feeding track extending in the X direction; a transit assembly including a transit seat that moves along a transit path between a transit position of the sample analyzer, which is directly above the sampling position, and a conventional sampling position, which is offset from the transit position in both directions X, Y, to transit the sample tube transported by the autosampler assembly; the sampling assembly comprises a sampling needle, the sampling needle moves above the middle swivel base along a sample conveying path, and a plurality of sample dividing positions are arranged on the sample conveying path; and the detection assembly comprises a plurality of reaction measuring tanks, each reaction measuring tank is positioned under one sample dividing position, the sample is sampled for a sample tube positioned on a middle rotary seat of the conventional sampling position and then moves along the sample conveying path, and the collected sample to be detected is injected into the reaction measuring tank below each sample dividing position.

The invention also provides a sample detection flow, which comprises the following steps: an automatic sample feeding step, wherein a sample pipe rack loaded with sample pipes moves along a sample feeding track in the X direction to feed samples towards the sample feeding displacement; a sample mixing step, namely grabbing a sample tube on a sample tube rack moving to the sampling position and uniformly mixing samples to be detected in the sample tube; a transit step, wherein the transit seat moves along a transit path to transit the uniformly mixed sample tube from the transit to a conventional sampling position, the transit is positioned right above the sampling position, and the conventional sampling position deviates from the transit in both directions of X, Y; and sampling and separating, wherein a sampling needle sucks a sample from a sample tube on the middle rotary seat which is moved to the conventional sampling position and moves along a sample conveying path in the Y direction, and the sucked sample is distributed into a reaction measuring pool for sample detection.

Compared with the prior art, the transfer component of the sample analyzer can form displacement in two directions at the same time, so that other components such as the arrangement and the movement of the sampling component are facilitated, the overall layout is flexible and reasonable, the overall mechanism is more compact, the coordinated operation of the components is smoother, the detection flow can be effectively accelerated, the detection efficiency is improved, and the sample collection after automatic sample injection and manual sample injection can be considered through the movement of the sampling component, so that the detection of emergency samples is facilitated.

Drawings

FIG. 1 is a schematic diagram of a sample analyzer according to an embodiment of the present invention.

Fig. 2 is a schematic view of a mixing assembly grip sample tube of the sample analyzer of fig. 1.

Fig. 3 is a schematic view of a lancing assembly lancing sample of the sample analyzer of fig. 1.

Fig. 4 is a schematic diagram of a mixing assembly and a relay assembly of the sample analyzer of the present invention.

Fig. 5 is a side view of fig. 4.

Fig. 6 is a schematic diagram of a mixing assembly of the inventive sample analyzer.

Fig. 7 is a schematic diagram of a relay assembly of the inventive sample analyzer.

Fig. 8 is a top view of fig. 7.

Fig. 9 is a schematic diagram of the transfer assembly of fig. 7 moved to a conventional sampling position.

FIG. 10 is a schematic diagram of a sample assembly of the inventive sample analyzer moved to a first sampling position.

FIG. 11 is a schematic diagram of the sampling assembly of FIG. 10 moved to a second sampling position.

FIG. 12 is a schematic view of another embodiment of the sample analyzer of the present invention.

Detailed Description

In order that the invention may be readily understood, a more complete description of the invention will be rendered by reference to the appended drawings. One or more embodiments of the present invention are illustrated in the accompanying drawings to provide a more accurate and thorough understanding of the disclosed subject matter. It should be understood, however, that the present invention may be embodied in many different forms and should not be construed as being limited to the embodiments set forth herein.

The same or similar reference numbers in the drawings correspond to the same or similar components; in the description of the present invention, it should be understood that, if there is an azimuth or positional relationship indicated by terms such as "upper", "lower", "left", "right", etc., based on the azimuth or positional relationship shown in the drawings, it is only for convenience of describing the present invention and simplifying the description, but it is not indicated or implied that the apparatus or element referred to must have a specific azimuth, be constructed and operated in a specific azimuth, and thus terms describing the positional relationship in the drawings are merely illustrative and should not be construed as limitations of the present patent, and specific meanings of the terms described above may be understood by those skilled in the art according to specific circumstances.

The invention provides a sample analyzer for detecting and analyzing biological samples, in particular blood samples. Fig. 1-3 illustrate an embodiment of a sample analyzer according to the present invention, which includes a plurality of components, such as an autosampler 10, a mixer 20, a relay 30, a sampling 40, a detector 50, an electrical control, etc. The automatic sample feeding assembly 10 is arranged outside a host of the sample analyzer and is positioned at the front side of the host, and is used for conveying a sample to be tested to a sampling position of the sample analyzer; the mixing component 20, the transferring component 30, the sampling component 40, the detecting component 50, the electric control component and the like are arranged inside the host, and the electric control component automatically coordinates the operation of other components in the whole sample detection flow, so that the sample detection is fully automated. The description of the orientation of the present invention is based on the placement direction of the sample analyzer when in use, and in the drawing, the X direction is the left-right direction, the Y direction is the front-back direction, and the Z direction is the up-down direction.

Typically, the sample to be tested is sealed in the sample tube 12, and a label is attached to the sample tube 12 to record corresponding information of the patient, so that the detection result can be automatically matched with the patient; multiple sample tubes 12 are placed on the same sample tube rack 14. The auto-sampling assembly 10 includes a sampling track 16 extending in the X-direction, and the sample tube rack 14 moves left and right along the sampling track 16 and passes through the sampling site. In the illustrated embodiment, the loading platform 18 and the unloading platform 19 are respectively disposed at the left and right ends of the sample feeding track 16. During automatic sample injection, a sample tube rack 14 loaded with sample tubes 12 is fed into a sample injection track 16 by a loading platform 18; then, the sample tube rack 14 moves to a sampling position along the sample injection track 16, the sample tubes 12 on the sample tube rack 14 at the sampling position are taken away by the mixing component 20 one by one for sampling, and the sampled sample tubes 12 are put back to the sample tube rack 14; finally, the sample tube rack 14 with the sampled sample tube 12 continues to move to the unloading platform 19 for unloading, and automatic batch sampling is completed.

Referring to fig. 4 to 6, the mixing assembly 20 includes a gripper 22 and a driving motor 24, such as a screw motor, for driving the gripper 22 to move up and down. The gripper 22 is disposed right above the sampling position, and moves up and down along the gripping path in the Z direction under the action of the drive motor 24 to grip the sample tube 12 for automatic sampling. The pick-and-place path intersects the sample introduction track 16 of the autosampler assembly 10 at the sampling location, and when the sample tube rack 14 is moved to the sampling location, the gripper 22 moves down to grasp the sample tube 12 on the sample tube rack 14. After the gripper 22 grips the sample tube 12, the sample tube 12 is firstly subjected to a mixing operation, and then the mixed sample tube 12 is transferred to the transfer assembly 30, and the transfer assembly 30 conveys the sample tube 12 to the conventional sampling position A0 for puncture sampling. The mixing operation of the sample tube 12 is performed before sampling to uniformly mix the sample to be tested in the sample tube 12, so as to avoid the influence on the accuracy of the sample detection result due to the static layering of the sample to be tested, especially the blood sample to be tested.

Specifically, blending assembly 20 further includes a rotating motor 26, with grip 22 being shown connected to rotating motor 26 by a pulley 28. After the grabbed sample tube 12 is lifted to a certain height by the grabbed gripper 22, the rotary motor 26 drives the gripper 22 and the grabbed sample tube 12 to rotate or swing at a proper frequency, and samples to be measured in the sample tube 12 are uniformly mixed. In some embodiments, the mixing assembly 20 further includes a dedicated mixing component that mixes the sample tube 12 by way of high frequency vibration, or the like. Different mixing modes are suitable for sample tubes 12 with different specifications, and the sample tubes 12 commonly used in sample detection comprise two types of common test tubes and micro test tubes, and compared with the common test tubes, the micro test tubes are much smaller in height and volume. In blood sample detection, a common test tube is used for containing venous blood with relatively large blood sampling amount and is uniformly mixed in a rotating or swinging mode; the micro-test tube is used for containing peripheral blood with relatively small blood sampling amount and is uniformly mixed in a vibration mode.

When the automatic sample feeding sample tube 12 is a common test tube, after the gripper 22 lifts the gripped common test tube by a certain height, the rotating motor 26 is started to drive the gripper 22 and the common test tube to rotate for uniform mixing operation. When the auto-sampling sample tube 12 is a micro-tube, the gripper 22 lifts the gripped micro-tube to a certain height, and then the special mixing component moves to the lower side of the gripper 22 to receive the micro-tube. Preferably, the special mixing component is provided with a mixing seat for fixing the micro test tube, and the mixing seat moves along a mixing path to convey the micro test tube to a mixing position. And in the mixing position, uniformly mixing the sample to be tested in the micro test tube in a high-frequency vibration mode and the like, so that the residue of the sample to be tested on the tube wall or the tube cap is reduced. After the mixing operation is completed, the micro test tube is conveyed to the lower part of the gripper 22 through the movement of the mixing seat, and the gripper 22 moves downwards to grasp the mixed micro test tube. In a specific application, the mixing path of the mixing seat can extend along the X direction or the Y direction and can be set according to the internal space of the instrument.

As shown in fig. 7-9, the transfer assembly 30 includes a central swivel mount 32, and a hole 320 is provided in the central swivel mount 32 for receiving the homogenized sample tube 12. In some embodiments, an adapter is mounted within the aperture 320 for adapting to different gauges of sample tubes 12; or, the transfer seat 32 may be provided with a plurality of different hole sites 320 for respectively accommodating the sample tubes 12 with different specifications, so that the sample tubes 12 can be fixed on the transfer seat 32, thereby facilitating subsequent puncture and sampling. The middle rotary seat 32 moves between the middle rotary seat B0 and the conventional sampling position A0 along a middle rotary path, wherein the middle rotary seat B0 is positioned right below the grip 22, the middle rotary seat 32 and the grip-release path of the grip 22 are intersected in a three-dimensional way, after the sample tube 12 subjected to the uniform mixing operation moves down a certain distance along with the grip 22, the grip 22 is opened, and the uniformly mixed sample tube 12 can be placed in the hole site 320 of the middle rotary seat 32; the conventional sample bit A0 is offset a distance in both directions X, Y relative to the neutral bit B0, with the conventional sample bit A0 being in the illustrated embodiment in a position to the right of the neutral bit B0.

As shown in fig. 8, the transfer assembly 30 further includes a first slide rail 34 and a second slide rail 36 guiding the middle swivel mount 32 to move toward the normal sampling position A0, wherein the first slide rail 34 extends in the Y direction and the second slide rail 36 extends in the X direction. The middle swivel mount 32 is slidably connected to the first slide rail 34, the first slide rail 34 is slidably connected to the second slide rail 36, and the second slide rail 36 is fixedly installed in the host. By the arrangement of the first slide rail 34 and the second slide rail 36, the transfer seat 32 can be displaced in both directions X, Y at the same time, and can move between the transfer position B0 and the normal sampling position A0 along an oblique linear path (shown by a broken line in fig. 8). Preferably, the first slide rail 34 and the second slide rail 36 are both higher than the sample feeding rail 16 of the auto-feeding assembly 10, so that the transit path of the transit seat 32 is located above the sample feeding rail 16, and the movement of the transit seat 32 does not interfere with the sample tube rack 14 and the sample tube 12 on the sample tube rack 14.

The transfer assembly 30 further comprises a first driving member 38 and a second driving member 39, wherein the first driving member 38 and the second driving member 39 are preferably motors, the first driving member 38 is in transmission connection with the transfer seat 32, and the transfer seat 32 is driven to move along the first sliding rail 34 along the Y direction; the second driving piece 39 is in transmission connection with the first sliding rail 34, and drives the first sliding rail 34 to drive the middle rotating seat 32 to move along the second sliding rail 36 in the X direction. In this embodiment, the middle rotating seat 32 is fixedly connected to the first sliding block 33, and the first sliding block 33 is slidably connected to the first sliding rail 34 and is in concave-convex fit with the first sliding rail; the first sliding rail 34 is fixedly connected to the second sliding block 35, and the second sliding block 35 is slidably connected to the second sliding rail 36 and is in concave-convex fit with the second sliding rail. The first driving piece 38 is in transmission connection with the first sliding block 33, and the middle rotating seat 32 is driven to move back and forth through the first sliding block 33; the second driving piece 39 is in transmission connection with the second sliding block 35, and drives the first sliding rail 34, the first sliding block 33 and the transfer seat 32 to move left and right through the second sliding block 35.

In this embodiment, the transfer assembly 30 further includes a third sliding rail 371 and a third sliding block 373 that are slidably connected, and the third sliding block 373 is in concave-convex fit with the third sliding rail 371. The third sliding rail 371 is fixedly arranged in the host and is parallel to the first sliding rail 34; the third slider 373 is in driving connection with the first driving member 38 and is movable back and forth with respect to the third slide rail 371. The third slider 373 and the first slider 33 are connected by a guide lever 375 such that the third slider 373 can move synchronously in the Y direction with the first slider 33. In the illustrated embodiment, the guide bar 375 extends in the X-direction and is disposed parallel to the second slide rail 36. One end of the guide rod 375 is fixedly connected with the third slider 373, and the other end is movably connected with the first slider 33, so that the first slider 33 and the third slider 373 can relatively move in the X direction.

In the illustrated embodiment, the guide rod 375 has a guide groove 377 formed therein, the guide groove 377 extending in the X-direction; the first slider 33 is provided with a guide post 331 protruding thereon, and the guide post 331 is movably inserted into the guide groove 377. Under the action of the second driving member 39, the first slide rail 34 moves in the X direction relative to the second slide rail 36, and the guide post 331 moves laterally in the guide groove 377, so that the first slider 33 and the third slider 373 move relatively in the X direction. In some embodiments, the guide rod 375 may be fixedly connected to the first slider 33 and movably connected to the third slider 373, so that the synchronous movement in the Y direction and the relative movement in the X direction can be achieved. By the arrangement of the third slide rail 371, the third slider 373 and the guide rod 375, the stability of the movement of the middle swivel mount 32 can be increased.

In the illustrated embodiment, the first driving member 38 and the second driving member 39 are disposed at the rear of the first sliding rail 34 and the second sliding rail 36, the first driving member 38 is in transmission connection with the third sliding block 373 through the first belt pulley 311, and the second driving member 39 and the second sliding block 35 are in transmission connection through the second belt pulley 313, so that long-distance power transmission can be realized, the change of the power transmission direction can be realized, and the arrangement of elements is convenient. It should be understood that the first driving member 38 and the second driving member 39 may be driving members such as cylinders or the like for providing driving force for the movement of the transfer seat 32; the first pulley 311 and the second pulley 313 transmit power between the first driving member 38, the second driving member 39 and the transfer seat 32, and other transmission elements, such as a gear set, may be selected according to the internal space of the main machine and the power transmission requirement.

When the first driving member 38 is started, the first pulley 311 drives the third slider 373 to move back and forth, and the third slider 373 drives the first slider 33 to move back and forth through the guide rod 375, so that the middle rotary base 32 is finally displaced along the first sliding rail 34 in the Y direction. When the second driving member 39 is started, the second pulley 313 drives the second slider 35 to move left and right, and the second slider 35 drives the first slider 33 to move left and right accordingly, so that the middle rotary base 32 is finally displaced along the second sliding rail 36 in the X direction. When the first driving member 38 and the second driving member 39 are started at the same time, the first sliding rail 34 and the second sliding rail 36 are connected in a sliding manner, the transfer seat 32 moves left and right along with the second sliding block 35 while moving back and forth along with the first sliding block 33, displacement is formed in two directions X, Y, and the actual moving direction of the transfer seat 32 is an oblique direction which is deflected by a certain angle relative to the two directions X, Y.

The autosampler 10, the mixing assembly 20 and the transfer assembly 30 are mainly started in an autosampler mode of the sample analyzer, so that the sample tube 12 can sample in batches and be quickly transported to a conventional sampling position A0 for puncture sampling after sample injection. In practical applications, samples of emergency patients often need to be detected preferentially, so the sample analyzer is further configured with an emergency detection mode, and a user can start the emergency detection mode through an operation screen of the host or a key on the host when needed. In the emergency detection mode, the sample tube 12 loaded with the emergency sample can be manually sampled and subjected to team detection to acquire a detection result as soon as possible. Generally, the manual sampling in the emergency detection mode has two modes of open sampling and closed sampling, wherein the open sampling is simple and convenient in operation, the closed sampling can reduce the time of exposing the emergency sample in the air, and a user can select a proper manual sampling mode according to the needs.

In the embodiment shown in fig. 1, the sample analyzer is configured with an emergency department 60 within its host for manual closed feeding of emergency samples. The emergency department 60 is provided with an emergency seat 62 for placing the sample tube 12 carrying emergency samples. The emergency seat 62 is movable along an emergency path between an off-board emergency sample placement site C0 and an on-board emergency sample placement site A1 to effect input and output of the emergency sample tube 12. Accordingly, the host machine is provided with openable bin gates at positions corresponding to emergency bins 60. Preferably, the emergency sample placement site C0, the emergency sample placement site A1, and the normal sample placement site A0 are arranged back and forth along the Y direction. Preferably, the emergency sampling station A1 is located on the front side of the entire transfer assembly 30, avoiding movement of the intermediate swivel mount 32 from interfering with the sample tube 12 at the emergency sampling station A1.

When the emergency detection mode is started, the emergency seat 62 of the emergency cabin 60 extends outwards to an emergency sample placement position C0, and a user opens the cap of the sample tube 12 of the emergency sample and places the sample tube into the emergency seat 62; thereafter, the emergency seat 62 moves back to the emergency sampling position A1, the sampling assembly 40 moves above the emergency sampling position A1, and the sampling needle 42 moves down and extends into the sample tube 12 to suck a dose of emergency sample, so as to realize closed sampling and preferential sampling of the emergency sample. After the sampling is completed, the emergency seat 62 is extended out to the emergency sample placement position C0 with the sample tube 12, so that a user can directly take out the sample tube 12; the sampling needle 42 injects the collected emergency sample into the detection assembly 50 for sample detection.

In the embodiment shown in fig. 12, the sample analyzer is provided with an opening 11 at the front side of the main body for manual open feeding of emergency samples. When the emergency detection mode is activated, the sampling assembly 40 is moved over the emergency sampling site A1, and the user places the capped emergency sample tube 12 directly into the emergency sampling site A1 through the opening 11 and causes the sampling needle 42 to be inserted into the sample tube 12. Preferably, the sample analyzer is provided with a button 13 at the rear side of the emergency sample position A1, and when the user places the sample tube 12 of the emergency sample at the emergency sample position A1, the user can press the button 13 in a proper direction to start the power element of the sampling assembly 40, such as a dosing pump, so that the sampling needle 42 sucks the emergency sample in the sample tube 12, and the preferential sampling of the emergency sample is completed. After sampling is completed, the user directly takes the sample tube 12 away and the sampling needle 42 injects the collected emergency sample into the detection assembly 50 for sample detection.

As shown in fig. 11-12, the sampling assembly 40 includes a sample presentation path 44 extending in the Y-direction, and the sampling needle 42 is movable along the sample presentation path 44 to a first sampling position, a second sampling position, and a plurality of sample dividing positions. Wherein, the first sampling position is right above the normal sampling position A0 and is used for puncture sampling of the automatic sample injection sample tube 12 conveyed by the centering swivel mount 32; the second sampling position is positioned right above the emergency sampling position A1 and is used for sampling a sample tube 12 of the emergency sample of manual sampling; the sample separation position is located above the detection assembly 50, and the detection assembly 50 includes a plurality of reaction measurement cells distributed along the Y direction, where each reaction measurement cell corresponds to one of the sample separation positions. The sample to be measured sucked by the sampling needle 42 is dispensed into each reaction measuring cell at each sample dispensing position, mixed with the detection reagent in the reaction measuring cell, and after the reaction, the final detection result is obtained through the detection elements such as light, electricity and the like.

When the sample analyzer of the invention is used, an automatic sample injection mode is used in a normal state, and the sample analyzer comprises: an automatic sample feeding step, namely moving a sample tube rack 14 loaded with a sample tube 12 towards a sample displacement along a sample feeding track 16 in the X direction under the action of an automatic sample feeding assembly 10; a sample mixing step, in which the gripper 22 of the mixing assembly 20 moves along a gripping path in the Z direction to grip the sample tube 12 on the sample tube rack 14 and mix the samples to be measured in the sample tube uniformly; a transfer step, in which the transfer seat 32 is moved to a transfer position B0, the gripper 22 places the uniformly mixed sample tube 12 in the transfer seat 32, and the transfer seat 32 moves along a transfer path to transfer the uniformly mixed sample tube 12 to a conventional sampling position A0; and a sampling and sample dividing step, wherein the sampling needle 42 is moved to a first sampling position, then descends to a certain height to suck samples from the sample tube 12 on the middle rotary seat 32, then moves to each sample dividing position along the sample conveying path in the Y direction to divide the sucked samples into the reaction measuring pool for sample detection, and a corresponding detection result is obtained.

The sample tube 12 after completion of puncture sampling is transported again by the middle swivel base 32, and returns from the normal sampling position A0 to the middle swivel base B0. In transition B0, gripper 22 moves down and grips sample tube 12 on intermediate swivel 32, returning it to sample tube rack 14. Finally, the sample tube rack 14 carries the sampled sample tube 12 to continue along the sample introduction track 16, and finally reaches the unloading platform 19 for unloading. The process after the sample tube 12 is pierced and sampled and the sample detection of the detection assembly 50 can be performed simultaneously, so that extra time waste is avoided. In addition, in the whole process of sample detection, in order to avoid the mutual interference of the operation of each component, the gripper 22 can avoid the middle position B0 when grabbing the sample tube 12 from the sample tube rack 14, for example, the middle position B0 can be moved to the position A0; after the sample mixing operation is completed, the transfer block 32 is again moved to the transfer position B0 to receive the mixed sample tube 12.

The middle rotary seat 32 moves along the middle rotary path to transport the sample tube 12 to the conventional sampling position A0 for puncture sampling, and the first driving piece 38 and the second driving piece 39 can be started at the same time, so that the middle rotary seat 32 is displaced in both directions at the same time X, Y. In some embodiments, the movement of the middle rotary seat 32 may also be that the first driving member 38 and the second driving member 39 are started sequentially, and at this time, the transfer path is in a zigzag shape as a whole, and the transfer seat 32 may move to the front of the normal sampling position A0 along the first path in the X direction and then move to the normal sampling position A0 along the second path in the Y direction; alternatively, the transfer seat 32 may first move to the left of the normal sampling position A0 along the second path in the Y direction and then move to the normal sampling position A0 along the first path in the X direction; alternatively, the transfer block 32 moves a certain distance along the first path in the X direction first, moves to the left of the normal sampling position A0 along the second path in the Y direction second, and moves a certain distance to the normal sampling position A0 along the third path in the X direction last. The middle swivel base 32 can have the shortest moving path when moving obliquely and linearly along the connecting line between the middle swivel base B0 and the conventional sampling position A0, correspondingly has the shortest moving time, and can effectively reduce the time consumption of sample detection; when the middle swivel base 32 moves along the folding line, other components can be avoided more conveniently, and interference is avoided.

According to the invention, through the design of the transfer assembly 30, the transfer seat 32 can generate displacement in two directions of X, Y, so that the middle position B0 and the conventional sampling position A0 can be staggered in two directions of X, Y, and the positions of the mixing assembly 20, the sampling assembly 40 and the detection assembly 50 are not limited by the transfer assembly 30 any more, and can be flexibly arranged according to the space in a host; meanwhile, the sample tube 12 can move in the XY plane through the movement of the middle rotary seat 32 in the X, Y directions, the hand grip 22 of the mixing component 20 only needs to move up and down to realize the transfer of the sample tube 12 between the automatic sample feeding component 10 and the transit component 30, the coordination operation among the components is simpler, the sample detection flow is effectively accelerated, and the detection efficiency is improved. In addition, the transfer seat 32 can move obliquely, so that the actual moving path of the transfer seat 32 is shortened to be the shortest, the time for transferring the sample tube 12 by the transfer seat 32 is shortened, and the detection efficiency is further improved.

When the detection requirement of the emergency sample exists, the sample analyzer of the invention starts an emergency detection mode, and the sample tube 12 loaded with the emergency sample is placed at the emergency sampling position A1 in an open sampling or closed sampling mode after the cover is pulled out. When the sample tube 12 is open, as shown in fig. 11 and 12, the sampling needle 42 is first moved forward to the second sampling position, the user directly positions the sample tube 12 rancour below the sampling needle 42, and then presses the button 13 to cause the sampling needle 42 to aspirate the emergency sample. When the sample tube 12 is closed for sample feeding, as shown in fig. 1 and 11, the emergency sample bin 60 and the sampling assembly 40 are in linkage through the control assembly, and when the emergency seat 62 moves to the emergency sample position A1 in the machine with the sample tube 12, the sampling needle 42 moves forward to the second sampling position and then moves downward to extend into the sample tube 12 to suck the emergency sample. After sampling is completed, the sampling needle 42 is moved back to each sample division position to distribute the collected emergency samples to each reaction measurement cell of the detection assembly 50 to obtain detection results.

Compared with automatic sampling, the emergency sample sampled manually is usually just collected, so that the emergency sample is in a uniformly mixed state, or the emergency sample can be manually shaken uniformly by a user, so that the emergency sample can be sampled directly after sampling, and the uniform mixing operation is not needed. According to the emergency sample sampling device, the emergency sampling position A1 is arranged at the front side of the conventional sampling position A0, the sampling needle 42 moves forwards to the first sampling position when the emergency detection mode is started, and the manually-sampled sample tube 42 is positioned at the emergency sampling position A1 and is positioned right below the sampling needle 42 after sample injection, so that the sample tube 12 of an emergency sample can be directly sampled after sample injection, position allocation is not needed through the transit assembly 40, the emergency sample detection process is simplified to the greatest extent, and the time consumption of emergency sample detection is reduced. Moreover, the sampling needle 42 can give consideration to manual sampling, sampling after automatic sampling and sample separation after sampling by moving back and forth, so that the integral structure of the sample analyzer is further simplified, and the sample detection flow is further optimized.

It should be noted that the present invention is not limited to the above embodiments, and those skilled in the art can make other changes according to the inventive spirit of the present invention, and these changes according to the inventive spirit of the present invention should be included in the scope of the present invention as claimed.

Claims (10)

1. A sample analyzer, comprising:

the automatic sample feeding assembly is used for conveying a sample tube containing a sample to be tested to a sampling position of a sample analyzer along a sample feeding track extending in the X direction;

a transit assembly including a transit seat that moves along a transit path between a transit position of the sample analyzer, which is directly above the sampling position, and a conventional sampling position, which is offset from the transit position in both directions X, Y, to transit the sample tube transported by the autosampler assembly;

the sampling assembly comprises a sampling needle, the sampling needle moves above the middle swivel base along a sample conveying path, and a plurality of sample dividing positions are arranged on the sample conveying path; and

the detection assembly comprises a plurality of reaction measuring tanks, each reaction measuring tank is located under one of the sample dividing positions, the sample is sampled for a sample tube located on a middle rotary seat of the conventional sampling position and then moves along the sample conveying path, and the collected sample to be detected is injected into the reaction measuring tank below each sample dividing position.

2. The sample analyzer of claim 1, wherein the transit path of the center-swivel mount is a straight path, offset by an angle with respect to both the X-direction and the Y-direction.

3. The sample analyzer of claim 1, wherein the transit path is a polyline path comprising a first path and a second path that are vertically connected, the first path extending in the X-direction and the second path extending in the Y-direction; or, the device comprises a first path, a second path and a third path which are sequentially connected, wherein the first path, the third path extend along the X direction, and the second path extend along the Y direction.

4. A sample analyzer according to claim 2 or 3, further comprising emergency sampling bits, the emergency sampling bits and the regular sampling bits being arranged one after the other in the Y-direction; the sample feeding path of the sampling needle extends along the Y direction.

5. The sample analyzer of claim 4, further comprising a closed cartridge provided with an emergency seat for receiving a sample tube loaded with an emergency sample, the emergency seat being movable between an off-board emergency sample placement position and the emergency sample position, the emergency sample placement position, the emergency sample position, and the normal sample position being arranged back and forth along the Y-direction.

6. The sample analyzer of claim 4, wherein the sample analyzer is open at a location corresponding to the emergency sample site for manual open sampling of a sample tube loaded with emergency samples.

7. The sample analyzer of claim 6 wherein the sample analyzer is provided with a button behind the emergency sampling site for activating a powered element of the sampling needle.

8. The sample analyzer of claim 1, further comprising a blending assembly including a grip disposed directly above the transition and having a Z-directed grip path.

9. The sample analyzer of claim 8, wherein the mixing assembly further comprises a dedicated mixing component comprising a mixing seat for receiving a micro-tube, the mixing seat moving along a mixing path in either the X-direction or the Y-direction.

10. A sample detection procedure for use in a sample analyzer according to any one of claims 1 to 9, comprising the steps of:

an automatic sample feeding step, wherein a sample pipe rack loaded with sample pipes moves along a sample feeding track in the X direction to feed samples towards the sample feeding displacement;

a sample mixing step, namely grabbing a sample tube on a sample tube rack moving to the sampling position and uniformly mixing samples to be detected in the sample tube;

a transit step, wherein the transit seat moves along a transit path to transit the uniformly mixed sample tube from the transit to a conventional sampling position, the transit is positioned right above the sampling position, and the conventional sampling position deviates from the transit in both directions of X, Y; and

and in the sampling and sample dividing step, a sampling needle sucks samples from a sample tube on the middle rotary seat which is moved to the conventional sampling position and moves along a sample conveying path in the Y direction, and the sucked samples are respectively injected into a reaction measuring pool for sample detection.