CN117191528B - Full-automatic immunohistochemical dyeing machine with constant temperature and humidity function - Google Patents

Full-automatic immunohistochemical dyeing machine with constant temperature and humidity function Download PDF

Info

Publication number
CN117191528B
CN117191528B CN202311464507.8A CN202311464507A CN117191528B CN 117191528 B CN117191528 B CN 117191528B CN 202311464507 A CN202311464507 A CN 202311464507A CN 117191528 B CN117191528 B CN 117191528B
Authority
CN
China
Prior art keywords
dyeing machine
fixedly connected
hole
worm
machine body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202311464507.8A
Other languages
Chinese (zh)
Other versions
CN117191528A (en
Inventor
杨春蕊
张向莲
许丽萍
梁锐
张晓阳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SECOND HOSPITAL OF TIANJIN MEDICAL UNIVERSITY
Original Assignee
SECOND HOSPITAL OF TIANJIN MEDICAL UNIVERSITY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SECOND HOSPITAL OF TIANJIN MEDICAL UNIVERSITY filed Critical SECOND HOSPITAL OF TIANJIN MEDICAL UNIVERSITY
Priority to CN202311464507.8A priority Critical patent/CN117191528B/en
Publication of CN117191528A publication Critical patent/CN117191528A/en
Application granted granted Critical
Publication of CN117191528B publication Critical patent/CN117191528B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The invention belongs to the field of immunohistochemical dyeing machines, in particular to a full-automatic immunohistochemical dyeing machine with constant temperature and constant humidity functions, which aims at solving the problems that the dyeing quality and the working efficiency of an immunohistochemical slice are reduced due to the fact that the antibody titer is greatly influenced by the change of the ambient temperature and humidity due to the fact that a dewaxing method of the existing dyeing machine is completed by manually immersing different reagent solutions in a microwave oven, a stainless steel pressure cooker, an electromagnetic oven or other heating appliances, and an antigen repairing mode is completed by manually, the time is consumed, the dyeing quality and the working efficiency of the immunohistochemical slice can be effectively improved, the structure is simple, the time is saved, and the application is flexible.

Description

Full-automatic immunohistochemical dyeing machine with constant temperature and humidity function
Technical Field
The invention relates to the technical field of immunohistochemical staining machines, in particular to a full-automatic immunohistochemical staining machine with constant temperature and humidity functions.
Background
In recent years, with the development of immunohistochemical techniques and the advent of various specific antibodies, many difficult tumors have been clearly diagnosed. Morphology is subjective and objective evidence is sought by immunohistochemical techniques. In conventional pathological diagnosis of tumors, it is difficult to make a definite morphological diagnosis in 5% -10% of cases by h.e. staining alone. In particular, the practical value of immunohistochemistry in tumor diagnosis and differential diagnosis is widely accepted, and the accuracy rate can reach 50-75% in differential diagnosis of low-differentiation or undifferentiated tumors. The immunohistochemical staining technique is an important technique in pathological technique, is one of important auxiliary means for making clear diagnosis on various diseases, the immunohistochemical staining machine is an immunohistochemical experimental device, and an operation tissue specimen is fixed by formaldehyde and other factors to cause antigen inactivation, so that the thermal antigen repair is unavoidable in the immunohistochemical experimental process, and the thermal antigen repair is required to be heated at high temperature.
In the prior art, the dewaxing method of the dyeing machine is implemented by manually soaking different reagent solutions, and the antigen repairing mode is implemented by manually using a microwave oven, a stainless steel pressure cooker, an electromagnetic oven or other heating appliances, so that the time is consumed, the degree of dependence on the labor is high, the influence of the temperature and humidity changes of the environment in different seasons is great, the temperature of a slide frame is required to be reduced by absolute alcohol in summer, and the antigen repairing time is required to be prolonged in winter, so that the immunohistochemical slices are easy to dry, strip and waste antibodies, the cost is increased, the dyeing quality of the immunohistochemical slices is reduced, and the full-automatic immunohistochemical dyeing machine with the constant temperature and humidity function is provided for solving the problems.
Disclosure of Invention
The invention aims to solve the problems that in the prior art, dewaxing methods of dyeing machines are carried out by manually immersing different reagent solutions, antigen restoration modes are completed by manually using a microwave oven, a stainless steel pressure cooker, an electromagnetic oven or other heating appliances, time is consumed, the degree of dependence on the labor is high, meanwhile, the antibody titer is greatly influenced by the change of environmental temperature and humidity in different seasons, the temperature is required to be reduced by a dry alcohol glass slide frame in summer, and the antigen restoration time is required to be prolonged in winter, so that the dyeing quality, the working efficiency and the cost of an immunohistochemical slice are reduced, and the full-automatic immunohistochemical dyeing machine with the constant temperature and constant humidity function is provided.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
the utility model provides a full-automatic immune group's dyeing machine that possesses constant temperature and humidity function, includes the dyeing machine body, the outside of dyeing machine body is connected with the chamber door, the outside fixed mounting of dyeing machine body has the box, the air intake has been seted up to one side of box, fixed mounting has the dust guard in the air intake, fixed mounting has electrical heating stick and branch in the box, the vent has all been seted up to the both sides inner wall of dyeing machine body, the vent on dyeing machine body right side communicates with each other with the box, be provided with intermittent type opening and closing mechanism on the left vent of dyeing machine body, the bottom fixed mounting of dyeing machine body has the base, be connected with dewaxing jar and water tank on the base, sliding mounting has the slide in the dyeing machine body, be connected with the placing tray on the slide, the bottom of placing tray is connected with the hot plate, a plurality of standing grooves have been seted up at the top of placing tray, be provided with rotary mechanism on the placing tray, first spout sliding mounting panel's bottom fixed mounting has the heating plate, the top fixed mounting plate has the connecting plate, be provided with reciprocating mechanism on the connecting plate, first spout in the dyeing machine body, first spout has, first groove has been seted up on the left side vent, the guide hole is all arranged on the guide shaft, two guide shafts are connected with two guide holes in the two guide shafts.
Preferably, a second through hole is formed in the top of the box body, a second worm is rotatably installed in the second through hole, one end of the second worm is fixedly connected with the first worm wheel, and the second worm wheel is meshed with the second worm wheel.
Preferably, the intermittent opening and closing mechanism comprises a baffle, a fourth through hole is formed in one side of the dyeing machine body, a first rotating shaft is rotatably installed in the fourth through hole, the outer side of the baffle is fixedly connected with one end of the first rotating shaft, a gear is fixedly installed at one end of the first rotating shaft, a first toothed bar is meshed with the gear, and one end of the first toothed bar is fixedly connected with the bottom of the mounting plate.
Preferably, the second rotating shaft is rotatably arranged on the inner wall of one side of the first empty groove, a U-shaped rod is fixedly arranged at one end of the second rotating shaft, two ends of the U-shaped rod are fixedly connected with the same gear ring, the gear ring is meshed with a second toothed rod, the inner wall of the bottom of the first sliding groove is provided with a mounting groove, the mounting groove is communicated with the first empty groove, the second toothed rod is slidably arranged in the mounting groove, and one end of the second toothed rod is fixedly connected with the bottom of the mounting plate.
Preferably, two symmetrical second sliding grooves are formed in the outer side of the rotating plate, inclined clamping blocks are slidably mounted in the two second sliding grooves, a plurality of inclined grooves are formed in the inner wall of the gear ring, the inclined clamping blocks are matched with the inclined grooves, springs are fixedly connected to the outer sides of the two inclined clamping blocks, and one ends of the two springs are fixedly connected with the inner walls of the two second sliding grooves respectively.
Preferably, a seventh through hole is formed in the inner wall of one side of the first empty groove, a rectangular rod is rotatably installed in the seventh through hole, the outer side of the rectangular rod is slidably connected with the inner wall of the rectangular groove, and a rotating plate is fixedly installed at one end of the rectangular rod.
Preferably, a sixth through hole is formed in one side of the sliding seat and is communicated with the second empty groove, a third rotating rod is rotatably installed in the sixth through hole, the first bevel gear is fixedly connected with the outer side of the third rotating rod, and a rectangular groove is formed in one end of the third rotating rod.
Preferably, the rotating mechanism comprises a second rotating rod, a fifth through hole is formed in the inner wall of the top of the second empty groove, the second rotating rod is rotatably installed in the fifth through hole, one end of the second rotating rod is fixedly connected with the bottom of the placing disc, a second bevel gear is fixedly installed at the other end of the second rotating rod, and the second bevel gear is meshed with the first bevel gear.
Preferably, the reciprocating mechanism comprises a first rotating rod, a third through hole is formed in one side of the dyeing machine body, the first rotating rod is rotatably installed in the third through hole, one end of the first rotating rod is fixedly connected with the second worm wheel, the other end of the first rotating rod is fixedly provided with a rotating wheel, the outer side of the rotating wheel is fixedly provided with a guide pillar, a sliding opening is formed in the connecting plate, and the guide pillar is slidably installed in the sliding opening.
Preferably, the motor is fixedly installed on the supporting rod, a first through hole is formed in the supporting rod, a first worm is rotatably installed in the first through hole, an impeller is fixedly installed on the outer side of the first worm, one end of the first worm is fixedly connected with an output shaft of the motor, and a first worm wheel is meshed with the first worm.
In the invention, the full-automatic immunohistochemical dyeing machine with the constant temperature and humidity functions has the beneficial effects that:
1. this scheme is when opening motor and electrical heating stick, and the motor drives first worm and rotates, and first worm drives the impeller rotation, and the wind pressure that the impeller rotation produced can blow the heat that the electrical heating stick produced to the colorant body in through the vent, and then can guarantee the internal temperature of colorant invariable.
2. According to the scheme, when the first worm rotates, the first worm wheel drives the second worm wheel to rotate, the second worm wheel drives the second worm wheel to rotate, the first rotating rod drives the rotating wheel to rotate, the guide pillar drives the connecting plate to vertically move, the mounting plate drives the heating plate to vertically move, and then the heating plate can automatically thermally repair the immunohistochemical slices on the placing plate, so that the dyeing quality and the working efficiency of the immunohistochemical slices are effectively improved.
3. This scheme is when the mounting panel is vertical to be removed, and the mounting panel drives first rack bar and drives the gear and rotate, and the gear drives the reciprocal rotation of first pivot, and first pivot drives the reciprocal rotation of baffle, and then the baffle can intermittently open and close the vent, guarantees that dyeing machine body inside temperature is invariable.
The invention can be used in the process of automatic dewaxing, hydration and antigen thermal restoration, has the functions of constant temperature and constant humidity, creates a 'wet box-like' environment for slices, prevents the slices from being separated and dried, saves antibodies, can effectively improve the dyeing quality and the working efficiency of immunohistochemical slices, has a simple structure, saves time and can be flexibly applied.
Drawings
Fig. 1 is a schematic diagram of a front view of a full-automatic immunohistochemical dyeing machine with constant temperature and humidity functions;
FIG. 2 is a schematic diagram of a side view of a fully automatic immunohistochemical staining machine with constant temperature and humidity functions;
FIG. 3 is a schematic diagram of an enlarged structure of the portion A in FIG. 1 of the full-automatic immunohistochemical staining machine with constant temperature and humidity function;
FIG. 4 is a schematic diagram of the enlarged structure of the portion B in FIG. 1 of the full-automatic immunohistochemical staining machine with constant temperature and humidity function;
fig. 5 is a schematic diagram of an enlarged structure of a part C in fig. 2 of a full-automatic immunohistochemical staining machine with constant temperature and humidity function according to the present invention;
FIG. 6 is a schematic diagram of the enlarged structure of the portion D in FIG. 2 of the full-automatic immunohistochemical staining machine with constant temperature and humidity function;
fig. 7 is a schematic structural diagram of the matching of the second toothed bar and the gear ring of the full-automatic immunohistochemical dyeing machine with the constant temperature and constant humidity function;
fig. 8 is a schematic diagram of a three-dimensional structure with constant temperature and humidity function according to the present invention.
In the figure: 1. a dyeing machine body; 2. a door; 3. a base; 4. a case; 5. a dust-proof plate; 6. a support rod; 7. an electric heating rod; 8. a slide; 9. a first chute; 10. a mounting plate; 11. a heating sheet; 12. a guide shaft; 13. a connecting plate; 14. placing a tray; 15. a motor; 16. a first worm; 17. an impeller; 18. a first worm wheel; 19. a second worm; 20. a first rotating lever; 21. a second worm wheel; 22. a rotating wheel; 23. a guide post; 24. a second rotating rod; 25. a first rotating shaft; 26. a first toothed bar; 27. a gear; 28. a baffle; 29. a second toothed bar; 30. a second rotating shaft; 31. a U-shaped rod; 32. a gear ring; 33. a first empty slot; 34. a second empty slot; 35. a rectangular bar; 36. a rotating plate; 37. a sloping clamping block; 38. a spring; 39. a third rotating rod; 40. a first bevel gear; 41. a second bevel gear; 42. a heating plate; 43. a dewaxing cylinder; 44. a water tank.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments.
Example 1
Referring to fig. 1, 2 and 8, a full-automatic immunohistochemical dyeing machine with constant temperature and humidity function comprises a dyeing machine body 1, wherein a box door 2 is connected to the outer side of the dyeing machine body 1, a box body 4 is fixedly arranged on the outer side of the dyeing machine body 1, an air inlet is formed in one side of the box body 4, a dust-proof plate 5 is fixedly arranged in the air inlet, an electric heating rod 7 and a supporting rod 6 are fixedly arranged in the box body 4, ventilation openings are formed in the inner walls of two sides of the dyeing machine body 1, the ventilation openings on the right side of the dyeing machine body 1 are communicated with the box body 4, an intermittent opening and closing mechanism is arranged on the ventilation openings on the left side of the dyeing machine body 1 and comprises a baffle 28, a fourth through hole is formed in one side of the dyeing machine body 1, a first rotating shaft 25 is rotatably arranged in the fourth through hole, the outer side of the baffle 28 is fixedly connected with one end of the first rotating shaft 25, a gear 27 is fixedly arranged at one end of the first rotating shaft 25, the gear 27 is meshed with the first toothed bar 26, one end of the first toothed bar 26 is fixedly connected with the bottom of the mounting plate 10, the bottom of the dyeing machine body 1 is fixedly provided with the base 3, the base 3 is connected with the dewaxing cylinder 43 and the water tank 44, the sliding seat 8 is slidably arranged in the dyeing machine body 1, the sliding seat 8 is connected with the placing plate 14, the bottom of the placing plate 14 is connected with the heating plate 42, the top of the placing plate 14 is provided with a plurality of placing grooves, the placing plate 14 is provided with a rotating mechanism, one side inner wall of the dyeing machine body 1 is provided with the first sliding groove 9, the mounting plate 10 is slidably arranged in the first sliding groove 9, the bottom of the mounting plate 10 is fixedly provided with the heating plate 11, the top of the mounting plate 10 is fixedly provided with the connecting plate 13, the reciprocating mechanism is arranged on the connecting plate 13, the first empty groove 33 is arranged in the dyeing machine body 1, the second empty groove 34 is arranged in the sliding seat 8, two symmetrical guide holes are formed in the mounting plate 10, guide shafts 12 are slidably mounted in the two guide holes, one ends of the two guide shafts 12 are fixedly connected with the inner wall of the top of the dyeing machine body 1, and when the mounting plate 10 moves vertically, the two guide shafts 12 can play a role in stabilizing the vertical movement of the mounting plate 10.
Referring to fig. 3, a motor 15 is fixedly installed on a supporting rod 6, a first through hole is formed in the supporting rod 6, a first worm 16 is rotatably installed in the first through hole, an impeller 17 is fixedly installed on the outer side of the first worm 16, one end of the first worm 16 is fixedly connected with an output shaft of the motor 15, a first worm wheel 18 is meshed with the first worm 16, a second through hole is formed in the top of the box 4, a second worm 19 is rotatably installed in the second through hole, one end of the second worm 19 is fixedly connected with the first worm wheel 18, a second worm wheel 21 is meshed with the second worm 19, and when the first worm wheel 18 rotates, the second worm 19 can drive the second worm wheel 21 to rotate.
Referring to fig. 4, the reciprocating mechanism includes a first rotating rod 20, a third through hole is formed in one side of the dyeing machine body 1, the first rotating rod 20 is rotatably mounted in the third through hole, one end of the first rotating rod 20 is fixedly connected with a second worm wheel 21, a rotating wheel 22 is fixedly mounted at the other end of the first rotating rod 20, a guide post 23 is fixedly mounted at the outer side of the rotating wheel 22, a sliding opening is formed in the connecting plate 13, the guide post 23 is slidably mounted in the sliding opening, and when the first rotating rod 20 rotates, the rotating wheel 22 can drive the guide post 23 to do circular motion.
Referring to fig. 5, the rotating mechanism includes a second rotating rod 24, a fifth through hole is provided on the top inner wall of the second hollow groove 34, the second rotating rod 24 is rotatably installed in the fifth through hole, one end of the second rotating rod 24 is fixedly connected with the bottom of the placing tray 14, a second bevel gear 41 is fixedly installed at the other end of the second rotating rod 24, the second bevel gear 41 is meshed with a first bevel gear 40, when the first bevel gear 40 rotates, the second bevel gear 41 can drive the second rotating rod 24 to rotate, a sixth through hole is provided on one side of the sliding seat 8, the sixth through hole is communicated with the second hollow groove 34, a third rotating rod 39 is rotatably installed in the sixth through hole, the first bevel gear 40 is fixedly connected with the outer side of the third rotating rod 39, and a rectangular groove is provided at one end of the third rotating rod 39.
Referring to fig. 6 and 7, the second rotating shaft 30 is rotatably mounted on the inner wall of one side of the first hollow groove 33, the U-shaped rod 31 is fixedly mounted at one end of the second rotating shaft 30, the same gear ring 32 is fixedly connected at two ends of the U-shaped rod 31, the second toothed bar 29 is meshed with the gear ring 32, the mounting groove is formed on the inner wall of the bottom of the first hollow groove 9, the mounting groove is communicated with the first hollow groove 33, the second toothed bar 29 is slidably mounted in the mounting groove, one end of the second toothed bar 29 is fixedly connected with the bottom of the mounting plate 10, two symmetrical second sliding grooves are formed on the outer side of the rotating plate 36, oblique clamping blocks 37 are slidably mounted in the two second sliding grooves, a plurality of inclined grooves are formed on the inner wall of the gear ring 32, the oblique clamping blocks 37 are matched with the inclined grooves, springs 38 are fixedly connected to the outer sides of the two oblique clamping blocks 37, one ends of the two springs 38 are respectively fixedly connected with the inner walls of the two second sliding grooves, a seventh through hole is formed in one side of the first hollow groove 33, a rectangular bar 35 is rotatably mounted in the seventh through hole, the outer side of the rectangular bar 35 is slidably connected with the inner wall of the rectangular bar 35, one end of the rectangular bar 35 is slidably connected with the inner wall of the rectangular bar 35, and the rotating plate 36 is rotatably mounted on the inner side of the rectangular bar 35.
In this embodiment, when in use, the immunohistochemical slices to be thermally repaired are placed in a plurality of placing grooves, the box door 2 is closed, the motor 15, a plurality of electric heating rods 7 and the heating plates 11 are started, the motor 15 drives the first worm 16 to rotate, the first worm 16 drives the impeller 17 to rotate, the wind pressure generated by the rotation of the impeller 17 can blow the heat generated by the plurality of electric heating rods 7 into the dyeing machine body 1 through the ventilation opening, so as to ensure the constant temperature in the dyeing machine body 1, meanwhile, the first worm 16 drives the first worm wheel 18 to rotate, the first worm wheel 18 drives the second worm 19 to rotate, the second worm wheel 19 drives the second worm wheel 21 to rotate, the second worm wheel 21 drives the first rotating rod 20 to rotate, the first rotating rod 20 drives the rotating wheel 22 to rotate, the guide pillar 23 drives the guide pillar 23 to do circular motion, the guide pillar 23 can drive the connecting plate 13 to vertically reciprocate through the arrangement of the cooperation of the guide pillar 23 and the sliding opening, the connecting plate 13 drives the mounting plate 10 to vertically reciprocate, the mounting plate 10 drives the heating plate 11 to vertically reciprocate, the heating plate 11 can automatically thermally repair the immunohistochemical slices in the placing groove, meanwhile, the mounting plate 10 drives the first toothed bar 26 to vertically reciprocate, the first toothed bar 26 drives the gear 27 to rotate, the gear 27 rotates the opposite first rotating shaft 25, the first rotating shaft 25 drives the baffle 28 to rotate, the baffle 28 can intermittently open and close the vent, the internal temperature of the dyeing machine body 1 is effectively ensured to be constant, meanwhile, when the mounting plate 10 drives the second toothed bar 29 to vertically move downwards, the second toothed bar 29 drives the gear ring 32 to rotate clockwise, the chute is separated from the inclined clamping block 37, therefore, the gear ring 32 can not drive the two inclined clamping blocks 37 to rotate, when the second toothed bar 29 vertically moves upwards, the second toothed bar 29 drives the gear ring 32 to rotate anticlockwise, and then oblique fixture block 37 cooperatees with the chute, the ring gear 32 drives two oblique fixture blocks 37 and is circular motion, two oblique fixture blocks 37 drive revolve board 36 and rotate, revolve board 36 drives rectangle pole 35 and rotates, through rectangle pole 35 and rectangle groove matched with setting, rectangle pole 35 drives the rotation of third bull stick 39, third bull stick 39 drives first bevel gear 40 and rotates, first bevel gear 40 drives second bevel gear 41 and rotates, second bevel gear 41 drives second bull stick 24 and rotates, second bull stick 24 drives the rotatory certain angle of placing tray 14, and then can be to the immune group's section in a plurality of standing grooves thermal remediation in proper order, work efficiency is effectively improved, save time, and improve pathological diagnosis rate.
Example two
The difference between this embodiment and the first embodiment is that: the inside temperature of dyeing machine body 1 fixed mounting has temperature sensor and temperature controller, and temperature sensor, temperature controller and a plurality of electrical heating stick 7 connect gradually, and temperature sensor can monitor dyeing machine body 1 inside temperature, and when dyeing machine body 1 inside temperature reached the settlement threshold value, temperature sensor sent instruction to temperature controller, and temperature controller controls a plurality of electrical heating sticks 7 and opens and close automatically, and then can effectively improve constant temperature effect.
The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical scheme of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.

Claims (1)

1. The full-automatic immune grouping dyeing machine with the constant temperature and humidity function comprises a dyeing machine body (1), and is characterized in that the outer side of the dyeing machine body (1) is connected with a box door (2), an air inlet is formed in one side of the box body (4), a dust-proof plate (5) is fixedly installed in the air inlet, an electric heating rod (7) and a supporting rod (6) are fixedly installed in the box body (4), ventilation openings are formed in the inner walls of the two sides of the dyeing machine body (1), the ventilation openings on the right side of the dyeing machine body (1) are communicated with the box body (4), an intermittent opening and closing mechanism is arranged on the ventilation openings on the left side of the dyeing machine body (1), a base (3) is fixedly installed at the bottom of the dyeing machine body (1), a dewaxing cylinder (43) and a water tank (44) are connected to the base (3), a slide seat (8) is installed in the sliding mode, a placing disc (14) is connected to the bottom of the box body (4), a heating plate (42) is connected to the bottom of the placing disc (14), a plurality of placing grooves (14) are formed in the top of the placing disc (14), a plurality of placing grooves (9) are formed in the placing disc (14), a first sliding groove (9) is formed in the inner wall of the dyeing machine body, a first sliding groove (9) is arranged on the inner side of the sliding groove (9), the bottom of the mounting plate (10) is fixedly provided with a heating plate (11), the top of the mounting plate (10) is fixedly provided with a connecting plate (13), the connecting plate (13) is provided with a reciprocating mechanism, a first empty slot (33) is formed in the dyeing machine body (1), a second empty slot (34) is formed in the sliding seat (8), two symmetrical guide holes are formed in the mounting plate (10), guide shafts (12) are slidably arranged in the two guide holes, one ends of the two guide shafts (12) are fixedly connected with the inner wall of the top of the dyeing machine body (1), a motor (15) is fixedly arranged on the supporting rod (6), a first through hole is formed in the supporting rod (6), a first worm (16) is rotatably arranged in the first through hole, an impeller (17) is fixedly arranged on the outer side of the first worm (16), one end of the first worm (16) is fixedly connected with an output shaft of the motor (15), the first worm (18) is meshed with the first worm (16), a second through hole is formed in the top of the box (4), a second worm wheel (19) is rotatably arranged in the second through hole, a second worm wheel (19) is fixedly connected with a first rotary rod (20) on one side of the first worm (19), the first worm (19) is fixedly connected with the first rotary rod (20), the first rotating rod (20) is rotatably arranged in the third through hole, one end of the first rotating rod (20) is fixedly connected with the second worm wheel (21), the other end of the first rotating rod (20) is fixedly provided with a rotating wheel (22), the outer side of the rotating wheel (22) is fixedly provided with a guide pillar (23), a sliding opening is formed in the connecting plate (13), the guide pillar (23) is slidably arranged in the sliding opening, the intermittent opening and closing mechanism comprises a baffle plate (28), one side of the dyeing machine body (1) is provided with a fourth through hole, a first rotating shaft (25) is rotatably arranged in the fourth through hole, the outer side of the baffle plate (28) is fixedly connected with one end of the first rotating shaft (25), one end of the first rotating shaft (25) is fixedly provided with a gear (27), the gear (27) is meshed with a first toothed bar (26), one end of the first toothed bar (26) is fixedly connected with the bottom of the mounting plate (10), the top inner wall of the second idle groove (34) is provided with a fifth through hole, the second rotating rod (24) is rotatably arranged in the fifth through hole, the second rotating rod (24) is fixedly connected with the second bevel wheel (41) at one end of the second bevel wheel (24) and the second bevel wheel (40) is fixedly connected with the first bevel wheel (41), the sixth through hole is communicated with the second empty slot (34), a third rotating rod (39) is mounted in the sixth through hole in a rotating mode, the first bevel gear (40) is fixedly connected with the outer side of the third rotating rod (39), a rectangular slot is formed in one end of the third rotating rod (39), a second rotating shaft (30) is mounted on one side inner wall of the first empty slot (33) in a rotating mode, a U-shaped rod (31) is fixedly mounted at one end of the second rotating shaft (30), the same gear ring (32) is fixedly connected with two ends of the U-shaped rod (31), the gear ring (32) is meshed with a second toothed bar (29), a mounting slot is formed in the inner wall of the bottom of the first sliding slot (9), the mounting slot is communicated with the first empty slot (33), one end of the second toothed bar (29) is fixedly connected with the bottom of the mounting plate (10), a seventh through hole is formed in one side inner wall of the first empty slot (33), a rectangular slot (35) in a rotating mode, the outer side of the rectangular slot (35) is fixedly connected with the inner wall of the rectangular slot in a sliding mode, two inclined plates (37) are symmetrically mounted on the two inner side of the two inclined plates (37) in a sliding mode, two inclined plates (37) are symmetrically mounted on the two inclined plates (37) are mounted on the inner side of the two inclined plates (37), one end of each of the two springs (38) is fixedly connected with the inner walls of the two second sliding grooves.
CN202311464507.8A 2023-11-07 2023-11-07 Full-automatic immunohistochemical dyeing machine with constant temperature and humidity function Active CN117191528B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311464507.8A CN117191528B (en) 2023-11-07 2023-11-07 Full-automatic immunohistochemical dyeing machine with constant temperature and humidity function

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202311464507.8A CN117191528B (en) 2023-11-07 2023-11-07 Full-automatic immunohistochemical dyeing machine with constant temperature and humidity function

Publications (2)

Publication Number Publication Date
CN117191528A CN117191528A (en) 2023-12-08
CN117191528B true CN117191528B (en) 2024-01-30

Family

ID=88994651

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202311464507.8A Active CN117191528B (en) 2023-11-07 2023-11-07 Full-automatic immunohistochemical dyeing machine with constant temperature and humidity function

Country Status (1)

Country Link
CN (1) CN117191528B (en)

Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108949543A (en) * 2018-08-14 2018-12-07 孙伟鹏 The constant temperature and humidity device of food fermentation is used for sterilizing function
CN110319551A (en) * 2019-07-08 2019-10-11 杭州酒悦科技有限公司 A kind of wine cellar constant temperature and humidity device and its control system
CN210980596U (en) * 2019-12-13 2020-07-10 承德科翔新材料科技有限公司 Constant temperature drying cabinet convenient to remove
CN214014554U (en) * 2020-12-31 2021-08-20 深圳市乐塔驰电子有限公司 Wet tissue heater
CN214371374U (en) * 2021-01-29 2021-10-08 广东宏鑫工程质量检测有限公司 Electric heating air blast constant temperature drying cabinet that possesses alarming function
CN215353483U (en) * 2021-04-30 2021-12-31 上海观峰信息科技有限公司 Walk-in constant temperature and humidity box
CN113985042A (en) * 2021-10-25 2022-01-28 李英 A sample reagent storage equipment for water pollution administers
CN114034076A (en) * 2021-11-04 2022-02-11 薛瑞铭 Improved generation building intelligence temperature control equipment
CN114284143A (en) * 2021-12-15 2022-04-05 江苏汇成光电有限公司 Close frame and tear quick-witted centrifugal layer flash tank of glue
CN216285320U (en) * 2021-11-17 2022-04-12 中南大学湘雅医院 Immunohistochemical incubation box with uniform mixing and constant temperature and humidity functions
CN114438604A (en) * 2022-02-16 2022-05-06 山东道恩斯维特科技有限公司 Production equipment of bi-component non-woven fabric
WO2022135221A1 (en) * 2020-12-23 2022-06-30 山东骏腾医疗科技有限公司 Fully automatic drop staining device for tissue slice
WO2022193051A1 (en) * 2021-03-15 2022-09-22 徐州华沛智能制造科技有限公司 Drying and disinfection apparatus for toy production part
CN115452536A (en) * 2022-09-02 2022-12-09 福州安林生物科技有限公司 Immunohistochemical staining box for paraffin section and staining method thereof
CN219607299U (en) * 2022-12-28 2023-08-29 南京莱诺豪环保科技有限公司 Be used for clean unit of experiment platform constant temperature and humidity

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108949543A (en) * 2018-08-14 2018-12-07 孙伟鹏 The constant temperature and humidity device of food fermentation is used for sterilizing function
CN110319551A (en) * 2019-07-08 2019-10-11 杭州酒悦科技有限公司 A kind of wine cellar constant temperature and humidity device and its control system
CN210980596U (en) * 2019-12-13 2020-07-10 承德科翔新材料科技有限公司 Constant temperature drying cabinet convenient to remove
WO2022135221A1 (en) * 2020-12-23 2022-06-30 山东骏腾医疗科技有限公司 Fully automatic drop staining device for tissue slice
CN214014554U (en) * 2020-12-31 2021-08-20 深圳市乐塔驰电子有限公司 Wet tissue heater
CN214371374U (en) * 2021-01-29 2021-10-08 广东宏鑫工程质量检测有限公司 Electric heating air blast constant temperature drying cabinet that possesses alarming function
WO2022193051A1 (en) * 2021-03-15 2022-09-22 徐州华沛智能制造科技有限公司 Drying and disinfection apparatus for toy production part
CN215353483U (en) * 2021-04-30 2021-12-31 上海观峰信息科技有限公司 Walk-in constant temperature and humidity box
CN113985042A (en) * 2021-10-25 2022-01-28 李英 A sample reagent storage equipment for water pollution administers
CN114034076A (en) * 2021-11-04 2022-02-11 薛瑞铭 Improved generation building intelligence temperature control equipment
CN216285320U (en) * 2021-11-17 2022-04-12 中南大学湘雅医院 Immunohistochemical incubation box with uniform mixing and constant temperature and humidity functions
CN114284143A (en) * 2021-12-15 2022-04-05 江苏汇成光电有限公司 Close frame and tear quick-witted centrifugal layer flash tank of glue
CN114438604A (en) * 2022-02-16 2022-05-06 山东道恩斯维特科技有限公司 Production equipment of bi-component non-woven fabric
CN115452536A (en) * 2022-09-02 2022-12-09 福州安林生物科技有限公司 Immunohistochemical staining box for paraffin section and staining method thereof
CN219607299U (en) * 2022-12-28 2023-08-29 南京莱诺豪环保科技有限公司 Be used for clean unit of experiment platform constant temperature and humidity

Also Published As

Publication number Publication date
CN117191528A (en) 2023-12-08

Similar Documents

Publication Publication Date Title
CN103884565A (en) Pathological staining machine
CN109176748A (en) A kind of wood-worker engraving machine and the method using above-mentioned wood-worker engraving machine production furniture
CN117191528B (en) Full-automatic immunohistochemical dyeing machine with constant temperature and humidity function
CN101672765B (en) Testing box for accelerated environment
CN212761002U (en) Quick air-drying device for wax mould
CN212299738U (en) Drying device for design of cartoon handheld doll
CN210584895U (en) Can accelerate skin endless burning fat factor's culture apparatus
CN114440593A (en) Plant specimen drying-machine
CN209147613U (en) A kind of pressure Reduction Dryer with high efficiency drying function
CN219357304U (en) Ultra-clean cleaning table
CN219744866U (en) Temperature control structure of temperature change screening test box
CN214937722U (en) Platinum palladium rhodium purification equipment
CN219776136U (en) But solvent recycle's vacuum drying oven
CN220503031U (en) Electric heating constant temperature incubator
CN211576713U (en) Medical science inspection smear surface drying device
CN215909601U (en) Experimental sample drying device for environment monitoring station
CN219024362U (en) Environment simulation constant temperature structure
CN215598964U (en) Anti-oxidation testing arrangement is used in car cover production
CN219877407U (en) Pickled vegetable drying device
CN217993420U (en) Mould dew removing machine for injection molding
CN219939673U (en) Steam internal circulation energy-saving noodle steaming machine
CN219830525U (en) Modularized single-station incubation device
CN220083468U (en) Can dismantle intelligent electron blast drying cabinet of clearance
CN220326693U (en) Camel dairy products drying device
CN218973950U (en) Quality control sampling structure of fat beef production

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant