CN117157309A - 衣壳变异的重组腺相关病毒及其应用 - Google Patents

衣壳变异的重组腺相关病毒及其应用 Download PDF

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Publication number
CN117157309A
CN117157309A CN202280028081.9A CN202280028081A CN117157309A CN 117157309 A CN117157309 A CN 117157309A CN 202280028081 A CN202280028081 A CN 202280028081A CN 117157309 A CN117157309 A CN 117157309A
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seq
aav
cells
capsid protein
raav
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张文涛
廖成
宁威
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Shanghai Ruihongdi Pharmaceutical Co ltd
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Shanghai Ruihongdi Pharmaceutical Co ltd
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
    • A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202280028081.9A 2021-05-28 2022-05-27 衣壳变异的重组腺相关病毒及其应用 Pending CN117157309A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110594986 2021-05-28
CN202110594986X 2021-05-28
PCT/CN2022/095422 WO2022247917A1 (zh) 2021-05-28 2022-05-27 衣壳变异的重组腺相关病毒及其应用

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US (1) US20240252679A1 (https=)
EP (1) EP4349852A4 (https=)
JP (1) JP2024519888A (https=)
KR (1) KR20240014477A (https=)
CN (1) CN117157309A (https=)
AU (1) AU2022281825A1 (https=)
BR (1) BR112023024375A2 (https=)
CA (1) CA3219898A1 (https=)
MX (1) MX2023014041A (https=)
TW (1) TW202313096A (https=)
WO (1) WO2022247917A1 (https=)

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CN118754952A (zh) * 2024-09-06 2024-10-11 上海玮美基因科技有限责任公司 一种新型腺相关病毒及其应用
CN119039401A (zh) * 2024-08-19 2024-11-29 广州派真生物技术有限公司 腺相关病毒突变体及其应用
CN120118955A (zh) * 2025-03-05 2025-06-10 广州派真生物技术有限公司 一种高产aav的包装质粒及应用

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HRP20260137T1 (hr) * 2019-09-11 2026-03-13 Adverum Biotechnologies, Inc. Liječenje očnih neovaskularnih bolesti upotrebom aav2 varijanti koje kodiraju aflibercept
CN114729009A (zh) * 2019-10-31 2022-07-08 伯尔尼大学 用于眼部基因递送的aav载体变体

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CN119039401A (zh) * 2024-08-19 2024-11-29 广州派真生物技术有限公司 腺相关病毒突变体及其应用
WO2026040404A1 (zh) * 2024-08-19 2026-02-26 广州派真生物技术有限公司 腺相关病毒突变体及其应用
CN118754952A (zh) * 2024-09-06 2024-10-11 上海玮美基因科技有限责任公司 一种新型腺相关病毒及其应用
CN120118955A (zh) * 2025-03-05 2025-06-10 广州派真生物技术有限公司 一种高产aav的包装质粒及应用

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