CN117138005A - 一种缓解痛经的芳香中草药组合物及其制备方法和应用 - Google Patents
一种缓解痛经的芳香中草药组合物及其制备方法和应用 Download PDFInfo
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- CN117138005A CN117138005A CN202311236872.3A CN202311236872A CN117138005A CN 117138005 A CN117138005 A CN 117138005A CN 202311236872 A CN202311236872 A CN 202311236872A CN 117138005 A CN117138005 A CN 117138005A
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Abstract
本发明提供一种缓解痛经的芳香中草药组合物,包含以下组分:白芷、丁香、艾叶、小茴香、山柰、肉桂、当归、川芎、香附、木香、玫瑰花、桂花、苏合香。本发明根据寒凝血瘀型痛经的症状针对性地选择了13种芳香中草药,进一步通过制成缓解寒凝血瘀型痛经香包,对寒凝血瘀型痛经患者进行干预,显示所述香包能够缓解患者腹部疼痛及痛经伴随症状、降低疼痛灾难化水平、舒缓了负性情绪,突显了多种中草药芳香疗法作为缓解痛经的自然疗法的潜力,且非侵入性、便利的多种芳香中草药吸入疗法具有极好的耐受性。本发明扩大了芳香中草药及芳香疗法的应用范围,促进了中医原理在现代医疗实践中的理解和应用,有助于积极推进祖国医学文化的传承和发展。
Description
技术领域
本发明属于中药技术领域,更具体地,涉及一种缓解痛经的芳香中草药组合物及其制备方法和应用。
背景技术
痛经是一种常见的妇科疾病,其症状会对日常活动产生重大影响,可能导致睡眠质量下降,负性情绪及医疗费用增加、后期慢性疼痛和中枢敏感性的风险增加。近十年来,全球痛经的患病率有所上升,尤其是在20岁左右的大学生中。西方国家大学生的发病率约为64%至91%,而在中国发病率在41%至93%之间。西医推荐的常见止痛方案包括口服非甾体抗炎药和口服避孕药。虽然常规的西医方法可以快速缓解痛经症状,但容易复发并且存在潜在的药物依赖、胃肠道不适及过敏等不良反应。中医根据辨证分型治疗痛经,包括寒凝血瘀、气滞血瘀、气血虚弱、阳虚内寒、肝肾亏虚及湿热蕴结六种证型,而在痛经群体中以寒凝血瘀型为主,对此的治疗方法以常规的中医方法即口服草药煎剂、针灸和穴位敷贴并显示出其对痛经症状的改善具有积极作用。然而,一些大学生因为传统中药的苦味、针灸的疼痛以及穴位易过敏的风险更倾向于选择非侵入性的补充和替代医学疗法,如芳香疗法。
目前,芳香疗法主要依靠使用芳香精油来缓解痛经症状。然而,一些精油具有光毒性、致敏性和刺激性,其最佳稀释浓度的不确定性可能会对患者构成潜在风险,尤其是局部给药。相反,芳香中草药可以根据药性及药效进行分类,如芳香温通、芳香化湿和芳香开窍药。具体来说,芳香温通药具有温经活血止痛的作用,有助于缓解经期疼痛;芳香化湿药具有健脾开胃、助消化的作用,有助于缓解痛经引起的胃肠不适;芳香开窍药具有振奋精神的作用,有助于缓解与月经不适相关的负性情绪。多种芳香中草药的芳香疗法可能具有促进经络开放、血液循环和促进痛经自然缓解的潜力。
大学生面临着独特的生理、心理和社会挑战,同时他们拥有更大的自主权和独立性,有更强的健康意识并对参与健康相关活动表现出积极的态度。中医辨证分型的针对性治疗是影响疗效的关键因素之一。在大学生中,先天禀赋不足或后天调摄失养(如过量食用冷性食品和饮料、长时间暴露在寒冷潮湿的环境中、穿着暴露腹部和脚踝的衣服、月经期间暴露在外寒中)会使其容易受到寒邪的入侵。这种病机根源于肾阳不足,以寒凝血瘀为特征。因此,提供一种非侵入性、温和、以痛经患者舒适需求为导向的针对寒凝血瘀型痛经的芳香中草药组合物是十分必要的。
发明内容
本发明的目的在于克服现有技术中存在的上述缺陷和不足,提供一种缓解痛经的芳香中草药组合物。
本发明的第二个目的在于提供所述芳香中草药组合物的制备方法。
本发明的第三个目的在于提供所述芳香中草药组合物的应用。
本发明的上述目的是通过以下技术方案给予实现的:
一种缓解痛经的芳香中草药组合物,包含以下各组分:白芷、丁香、艾叶、小茴香、山柰、肉桂、当归、川芎、香附、木香、玫瑰花、桂花、苏合香。
本发明所述芳香中草药组合物立足于中医辨证分型,以中医药学为理论依据,针对痛经症状选用了13种芳香中草药,包括具有温肾助阳、散寒作用的丁香、艾叶、小茴香、肉桂和具有活血化瘀、止痛作用的白芷、当归、川芎、木香、香附、玫瑰花。此外,还选用了具有开胃止呕、安神定志等功效的山柰、苏合香和桂花,可利用上述13种芳香中草药的芳香属性,采用芳香疗法来缓解痛经。
白芷,为伞科植物白芷的干燥根,辛、温、芳香,归肺、胃经。传统功效有祛风解表、消肿排脓及燥湿止带,常用于盆腔炎、头痛等的治疗;现代研究的体外试验白芷水煎剂对志贺菌属、铜绿假单胞菌等有一定抑制作用。本发明取白芷作为痛经缓解香包的组成成分,意在取其传统芳香温通的药性、祛风解表的功效及现代的抗炎、镇痛作用,温经通脉止痛,缓解痛经腹部疼痛及痛经的头痛等全身伴随症状。
丁香,为桃金娘科植物丁香的干燥花蕾,辛、温、芳香,归脾、胃、肾经。传统功效有温肾助阳、温中降逆,常用于脘腹冷痛、恶心呕吐的治疗;现代研究的主要成分丁香油、乙酰丁香油酚等可减轻恶心呕吐,在体外对金黄色葡萄球菌、志贺菌属等具有抑制作用。本发明取丁香作为痛经缓解香包的组成成分,意在取其芳香温通、化湿的药性,温肾助阳、温中降逆的功效及现代的抗炎作用,醒脾开胃、助脾运化,缓解痛经的腹部疼痛及痛经的恶心呕吐等全身伴随症状。
艾叶,为菊科草本植物艾的干燥叶,苦、辛、温、芳香,归肝、脾、肾经。传统药效有散寒止痛、温经通络,常与当归、肉桂同用,用于妇女痛经、月经不调的治疗;现代研究的体外实验中艾叶挥发油对多种细菌、真菌有明显抑制作用。本发明取艾叶作为痛经缓解香包的组成成分,意在取其芳香温通的药性、散寒止痛、温经通络的功效及现代的抗炎作用,缓解痛经的腹部疼痛。
小茴香,为伞科草本植物茴香的果实,辛、温、芳香,归肝、肾、脾、胃经。传统功效有温肾散寒、理气和胃,常与当归、川芎同用,常用于行经腹痛、呕吐少食的治疗;现代研究中的挥发油有抑菌作用。本发明取小茴香作为痛经缓解香包的组成成分,意在取其芳香温通、化湿的药性,温肾散寒、理气和胃的功效及现代的抗炎作用,缓解痛经的腹部疼痛及痛经的恶心呕吐等全身伴随症状。
山柰,为姜科草本植物山奈的根茎,辛、温、芳香,归脾、胃经。传统功效有温中消食、祛瘀消肿,常用于寒湿吐泻的治疗;现代研究中的挥发油对常见致病真菌有不同程度的抑制作用。本发明取山柰作为痛经缓解香包的组成成分,意在取其芳香温通、化湿的药性,温中消食的功效及现代的抗炎作用,缓解痛经的腹部疼痛及痛经的恶心呕吐等全身伴随症状。
肉桂,为樟科常绿乔木植物肉桂的干皮,辛、甘、大热、芳香,归肾、脾、肝、心经。传统功效有补火助阳、散寒止痛、温经通脉,常用于痛经、腰膝疼痛的治疗;现代研究中的挥发油对一氧化碳、前列腺素诱导的子宫平滑肌收缩有抑制及抗炎作用。本发明取肉桂作为痛经缓解香包的组成成分,意在取其芳香温通的药性、补火助阳、散寒止痛、温经通脉的功效及现代的激素调节、抗炎作用,缓解痛经的腹部疼痛。
当归,为伞形科草本植物当归的根,辛、甘、温、芳香,归肝、脾、心经。传统功效有活血止痛、和血调经、补血养血及润肠通便,常用于腕腹疼痛、月经不调、盆腔炎等的治疗;现代研究中的挥发油具有镇痛、抗炎、抑菌作用。本发明取肉桂作为痛经缓解香包的组成成分,意在取其芳香温通的药性、活血止痛的功效及现代的镇痛、消炎、抑菌作用,缓解痛经的腹部疼痛。
川芎,为伞科草本植物川芎的根茎,辛、温、芳香,归肝、胆、心包经。传统功效有活血行气、散风止痛,常与当归、艾叶、白芍等同用,用于痛经、闭经、头痛等的治疗;现代研究中的挥发油对催产素诱导的子宫平滑肌具有抑制及抗菌作用。本发明取川芎作为痛经缓解香包的组成成分,意在取其芳香温通的药性、活血行气、散风止痛的功效及现代的激素调节、抗炎、抑菌作用,缓解痛经的腹部疼痛及痛经的头痛等全身伴随症状。
香附,为草本植物莎草的根茎,辛、微苦、甘、平,归肝、三焦经。传统功效有调经止痛、疏肝解郁,常与当归、白芍、红花等同用,用于月经不调、痛经、乳房胀痛、闭经、抑郁的治疗;现代研究中的挥发油对金黄色葡萄球菌、真菌具有抑制作用。本发明取香附作为痛经缓解香包的组成成分,意在取其调经止痛、疏肝解郁的功效及现代的抗炎、抑菌作用,缓解痛经的腹部疼痛、乳房胀痛及痛经的负性情绪等全身伴随症状。
木香,为菊科草本植物木香的根,辛、苦、温、芳香,归肝、脾、胃、大肠经。传统功效有行气止痛、健脾消食、疏肝利胆,常用于腹泻的治疗;现代研究中的挥发油对金黄色葡萄球菌、链球菌具有抑制作用。本发明取木香作为痛经缓解香包的组成成分,意在取其芳香温通的药性、行气止痛的功效及现代的抗炎、抑菌作用,缓解痛经的腹部疼痛及痛经的腹泻等全身伴随症状。
玫瑰花,为蔷薇科灌木玫瑰花的花蕾,甘、微苦、温,芳香,归肝、脾经。传统功效有活血调经、理气解郁,常用于月经不调、痛经、乳房胀痛的治疗;现代研究中的挥发油对肾上腺皮质激素诱导的子宫平滑肌收缩具有抑制作用。本发明取玫瑰花作为痛经缓解香包的组成成分,意在取其芳香温通的药性、活血调经、理气解郁的功效及现代的激素调节作用,增加中草药的愉悦花香气味,缓解痛经的腹部疼痛、乳房胀痛及痛经的负性情绪等全身伴随症状。
桂花,为木樨科常绿灌木的花,辛、温、芳香,归肺、肝、胃经。传统功效有散寒破结、化痰止咳,常与益母草、艾叶、月季花等同用,用于闭经腹痛的治疗;现代研究中的挥发油具有抗氧化、抗炎作用。本发明取玫瑰花作为痛经缓解香包的组成成分,意在取其芳香温通的药性、散寒破结的功效及现代的抗氧化、抗炎作用,增加中草药的愉悦花香气味,缓解痛经的腹部疼痛及痛经的负性情绪等全身伴随症状。
苏合香,为金缕梅科植物苏合香树所分泌的树脂,辛、温、芳香,归心、脾经。传统功效有开窍醒神、辟秽止痛,常用于心绞痛、昏迷的治疗;现代研究中具有局部缓解炎症的作用,本发明取苏合香作为痛经缓解香包的组成成分,意在取其芳香开窍的药性、开窍醒神的功效及现代的抗氧化、抗炎作用,缓解痛经的负性情绪全身伴随症状及预防腹痛疼痛加剧而导致的昏厥。
痛经产生的机制与前列腺素、催产素、一氧化氮、肾上腺素等内分泌激素,炎症和氧化应激相关且炎症反应产生的活性氧是氧化损伤的主要来源,因此中草药的激素调节能力、抗炎能力、抗氧化能力对痛经症状的缓解起到重要作用。现代药理学研究表明,川芎、肉桂中分离的肉桂醛和玫瑰分别对催产素,一氧化氮、前列腺素和肾上腺素诱导的子宫平滑肌收缩具有抑制作用。香附也可以抑制子宫平滑肌的收缩、具有明显的镇痛、镇静作用。此外,当归具有加强血流、减轻盆腔充血和滋养阴道的作用。丁香中分离的乙酰丁香酚、甲基丁香酚,艾叶中分离的有机酸、萜烯,桂花中的主要成分紫罗兰酮、类黄酮、多酚,小茴香以及苏合香具有抗氧化、抗炎作用。木香、山奈和白芷具有广泛的抗氧化、消炎、镇痛、血管舒张、镇静药理活性。现有研究表明,离子通道和G蛋白受体在连接和处理疼痛和嗅觉方面具有相互作用,大脑中相同的共享区域可处理疼痛感和嗅觉信息;此外,吸入疗法可以使药物有效成分通过呼吸系统进入血液,从而发挥药理作用,为芳香疗法中的吸入疗法缓解痛经提供了依据。
进一步地,所述芳香中草药组合物包含以下重量份数的各组分:白芷3~7份、丁香4~6份、艾叶3~7份、小茴香4~6份、山柰3~7份、肉桂8~12份、当归8~12份、川芎8~12份、香附8~12份、木香8~12、玫瑰花13~17份、桂花14~16份、苏合香0.05~0.15份。
优选地,所述芳香中草药组合物包含以下重量份数的各组分:白芷4~6份、丁香4~6份、艾叶4~6份、小茴香4~6份、山柰4~6份、肉桂9~11份、当归9~11份、川芎9~11份、香附9~11份、木香9~11份、玫瑰花14~16份、桂花14~16份、苏合香0.08~0.12份。
优选地,所述芳香中草药组合物包含以下重量份数的各组分:白芷5~6份、丁香5~6份、艾叶5~6份、小茴香5~6份、山柰5~6份、肉桂10~11份、当归10~11份、川芎10~11份、香附10~11份、木香10~11份、玫瑰花15~16份、桂花15~16份、苏合香0.1~0.12份。
优选地,所述芳香中草药组合物包含以下重量份数的各组分:白芷5~6份、丁香5~6份、艾叶5~6份、小茴香5~6份、山柰5~6份、肉桂10~11份、当归10~11份、川芎10~11份、香附10~11份、木香10~11份、玫瑰花15份、桂花15份、苏合香0.1份。
优选地,所述芳香中草药组合物包含以下重量份数的各组分:白芷5~6份、丁香5~6份、艾叶5~6份、小茴香5~6份、山柰5~6份、肉桂10份、当归10份、川芎10份、香附10份、木香10份、玫瑰花15份、桂花15份、苏合香0.1份。
最优选地,所述芳香中草药组合物包含以下重量份数的各组分:白芷5份、丁香5份、艾叶5份、小茴香5份、山柰5份、肉桂10份、当归10份、川芎10份、香附10份、木香10份、玫瑰花15份、桂花15份、苏合香0.1份。
本发明还提供上述任一所述缓解痛经中草药组合物的制备方法,步骤为分别取白芷、丁香、艾叶、小茴香、山柰、肉桂、当归、川芎、香附、木香、玫瑰花、桂花、苏合香研磨成粉,称取相应重量份数的中草药粉末进行混合。
本发明还提供上述任一所述芳香中草药组合物在制备缓解痛经的芳香疗法产品中的应用。
进一步地,所述痛经为寒凝血瘀型痛经。
本发明还提供一种用于缓解痛经的芳香疗法产品,所述产品含有上述任一所述的芳香中草药组合物。
进一步地,所述产品为中草药香包。
优选地,所述产品为所述芳香中草药组合物装入棉麻单层的香包袋。
优选地,所述产品为将上述制备方法制得的芳香中草药组合物装入棉麻、单层的透气香包袋,在月经期间以香包吸入形式的芳香疗法对痛经患者进行干预。
与现有技术相比,本发明具有以下有益效果:
本发明提供一种缓解痛经的芳香中草药组合物,根据寒凝血瘀型痛经的症状针对性地选择了13种芳香中草药,进一步通过制成缓解寒凝血瘀型痛经香包,对寒凝血瘀型痛经型患者进行干预,显示所述香包能够缓解患者腹部疼痛及痛经伴随症状、降低疼痛灾难化水平、舒缓了负性情绪,突显了多种中草药芳香疗法作为缓解痛经的自然疗法的潜力,且非侵入性、便利的多种芳香中草药吸入疗法具有极好的耐受性。本发明扩大了芳香中草药及芳香疗法的应用范围,促进中医原理在现代医疗实践中的理解和应用,有助于积极推进祖国医学文化的传承和发展。
附图说明
图1为干预前、干预1、2及3个月经周期的VAS平均值分析。
具体实施方式
以下结合说明书附图和具体实施例来进一步说明本发明,但实施例并不对本发明做任何形式的限定。除非特别说明,本发明采用的试剂、方法和设备为本技术领域常规试剂、方法和设备。
除非特别说明,以下实施例所用试剂和材料均为市购。
实施例1
取13种芳香中草药研磨成细粉末状,各中草药的称取份量如下:白芷5g、丁香5g、艾叶5g、小茴香5g、山柰5g、肉桂10g、当归10g、川芎10g、香附10g、木香10g、玫瑰花15g、桂花15g、苏合香0.1g,分别装进13cm×18cm的香包袋中后均匀混合,将口密封,以防粉末漏出,每包香包剂量为105.1g。
实施例2
取13种芳香中草药研磨成细粉末状,各中草药的称取份量如下:白芷7g、丁香6g、艾叶7g、小茴香6g、山柰7g、肉桂12g、当归12g、川芎12g、香附12g、木香12g、玫瑰花17g、桂花16g、苏合香0.15g,分别装进13cm×18cm的香包袋中后均匀混合,将口密封,以防粉末漏出,每包香包剂量为126.15g。
实施例3
取13种芳香中草药研磨成细粉末状,各中草药的称取份量如下:白芷3g、丁香4g、艾叶3g、小茴香4g、山柰3g、肉桂8g、当归8g、川芎8g、香附8g、木香8g、玫瑰花13g、桂花14g、苏合香0.05g,分别装进13cm×18cm的香包袋中后均匀混合,将口密封,以防粉末漏出,每包香包剂量为84.5g。
实施例4
取13种芳香中草药研磨成细粉末状,各中草药的称取份量如下:白芷6g、丁香6g、艾叶6g、小茴香6g、山柰6g、肉桂11g、当归11g、川芎11g、香附11g、木香11g、玫瑰花16g、桂花16g、苏合香0.12g,分别装进13cm×18cm的香包袋中后均匀混合,将口密封,以防粉末漏出,每包香包剂量为117.12g。
实施例5
取13种芳香中草药研磨成细粉末状,各中草药的称取份量如下:白芷4g、丁香4g、艾叶4g、小茴香4g、山柰4g、肉桂9g、当归9g、川芎9g、香附9g、木香9g、玫瑰花14g、桂花14g、苏合香0.08g,分别装进13cm×18cm的香包袋中后均匀混合,将口密封,以防粉末漏出,每包香包剂量为93.08g。
实施例6
取13种芳香中草药研磨成细粉末状,各中草药的称取份量如下:白芷6g、丁香6g、艾叶6g、小茴香6g、山柰6g、肉桂11g、当归11g、川芎11g、香附11g、木香11g、玫瑰花15g、桂花15g、苏合香0.1g,分别装进13cm×18cm的香包袋中后均匀混合,将口密封,以防粉末漏出,每包香包剂量为115.1g。
实施例7
取13种芳香中草药研磨成细粉末状,各中草药的称取份量如下:白芷6g、丁香6g、艾叶6g、小茴香6g、山柰6g、肉桂10g、当归10g、川芎10g、香附10g、木香10g、玫瑰花15g、桂花15g、苏合香0.1g,分别装进13cm×18cm的香包袋中后均匀混合,将口密封,以防粉末漏出,每包香包剂量为110.1g。
测试例1
采用实施例1~7制备所得香包和安慰剂对94个受试者进行了三个月经周期的干预,并以VAS(视觉模拟评分量表)进行评估。
为了排除食物、她人的香水气味等对香包气味造成影响,则在晚上睡觉时将香包挂在侧壁与鼻子水平距离约30厘米、高度相同的位置。干预时间为23:00至次日晨07:00共8h,次日晨统一装进规格为16cm×24cm的密封袋内进行保存,并在密封袋内放入两包食品干燥剂,以防香气快速走散、有效成分挥发、潮湿或受其他物体污染。为了确保每包香包功能的保持和效果的发挥,每4周更换一次香包,且月经来潮时继续使用。
实施例1香包的治疗结果如图1所示,显示香包干预效果明显优于安慰剂,VAS评分随着干预的进行呈现逐步下降的趋势。同时,实施例1对缓解寒凝血瘀型痛经的效果最佳,而实施例7、实施例6、实施例4、实施例5、实施例2、实施例3相比较于实施例1对缓解寒凝血瘀性痛经的效果依次降低,但仍然显著优于安慰剂。上述结果表明本发明实施例1~7的香包可有效缓解大学生寒凝血瘀型痛经症状,缓解了腹部疼痛及痛经伴随症状、降低了疼痛灾难化水平、舒缓了负性情绪,突显了多种中草药芳香疗法作为缓解痛经的自然疗法的潜力,且非侵入性、便利的多种芳香中草药吸入疗法具有极好的耐受性。随着对补充和替代医学疗法研究的不断增长,整合传统医学和现代医学的实践可以带来更全面、更个性化的医疗保健方法,最终提高痛经和其他妇科疾病患者的生活质量。扩大芳香中草药及芳香疗法的应用范围,促进中医原理在现代医疗实践中的理解和应用,积极推进祖国医学文化的传承和发展。
对比例1
根据表1称取不同组分的中草药组合物,研磨成粉后分别装进13cm×18cm的香包袋中后均匀混合,将口密封,以防粉末漏出。即与实施例1相比分别缺少其中一味芳香中草药。根据中草药组合物的药性,不同组分制备的中草药香包与实施例1相比,其药效降低,无法有效缓解寒凝血瘀型痛经。如组合物1中缺少白芷,会减弱该中草药组合物对寒凝血瘀型痛经的协同作用,影响寒凝血瘀型痛经疼痛的缓解效果;组合物2中缺少丁香,会减弱该中草药组合物在温热、醒脾开胃方面的作用,影响其对寒凝血瘀型痛经症状的缓解效果;组合物3中缺少艾叶,会减弱该中草药组合物温肾散寒的效果,影响痛经肾阳不足方面的缓解;组合物4中减少了小茴香,会对中草药组合物的温肾散寒功效的协同作用有影响;组合物5中减少了山柰,会对该中草药组合物在活血化瘀、温中消食方面的作用有影响。
表1不同中草药组合物组分表(单位:g)
组分 | 组合物1 | 组合物2 | 组合物3 | 组合物4 | 组合物5 |
白芷 | - | 5 | 5 | 5 | 5 |
丁香 | 5 | - | 5 | 5 | 5 |
艾叶 | 5 | 5 | - | 5 | 5 |
小茴香 | 5 | 5 | 5 | - | 5 |
山柰 | 5 | 5 | 5 | 5 | - |
肉桂 | 10 | 10 | 10 | 10 | 10 |
当归 | 10 | 10 | 10 | 10 | 10 |
川穹 | 10 | 10 | 10 | 10 | 10 |
香附 | 10 | 10 | 10 | 10 | 10 |
木香 | 10 | 10 | 10 | 10 | 10 |
玫瑰花 | 15 | 15 | 15 | 15 | 15 |
桂花 | 15 | 15 | 15 | 15 | 15 |
苏合香 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
总计 | 100.1 | 100.1 | 100.1 | 100.1 | 100.1 |
对比例2
取白芷、丁香、艾叶、小茴香、山柰、玫瑰花、桂花、苏合香研磨成粉,分别取以下重量的各组分:白芷5g、丁香5g、艾叶5g、小茴香5g、山柰5g、玫瑰花15g、桂花15g、苏合香0.1g,装入香包袋后均匀混合,将口密封,以防粉末漏出。与实施例1相比,该中草药香包缺少肉桂、当归、川芎、香附、木香5个组分,这些组分用于活血调经并协同发挥作用,缺少这些组分会影响中草药香包对于血液循环和经络调理的效果,从而无法实现对寒凝血瘀型痛经的缓解。
对比例3
取白芷、丁香、艾叶、小茴香、山柰、肉桂、当归、川芎、香附、木香研磨成粉,分别取以下重量的各组分:白芷5g、丁香5g、艾叶5g、小茴香5g、山柰5g、肉桂10g、当归10g、川芎10g、香附10g、木香10g,装入香包袋后均匀混合,将口密封,以防粉末漏出。与实施例1相比,该中草药香包缺少玫瑰花、桂花、苏合香,中草药香包的芳香特性减弱,从而影响患者对该香包的气味接受度,使患者降低愉悦感,易产生抵触情绪及其他负性情绪,从而也无法实现对寒凝血瘀型痛经的缓解。此外,少了苏合香可能会减小痛经的严重程度减轻的几率。以上对比例表明,即只有按照本发明13种芳香中草药进行综合搭配,才可以有效缓解寒凝血瘀型痛经。
另外本发明中的上述13种中草药本着芳香、天然有益、无毒副作用的原则被选用。并且在整个干预期间,所有参与者都通过问卷或口头报告的形式被彻底询问了她们可能经历的任何不良反应。直到整个干预结束,没有不良反应被报告,表明本发明的上述13种芳香中草药组合物无明显毒副作用。
显然,本领域的技术人员可以对本发明进行各种改动和变型而不脱离本发明的精神和范围。这样,倘若本发明的这些修改和变型属于本发明权利要求及其等同技术的范围之内,则本发明也意图包含这些改动和变型在内。
Claims (10)
1.一种缓解痛经的芳香中草药组合物,其特征在于,包含以下组分:白芷、丁香、艾叶、小茴香、山柰、肉桂、当归、川芎、香附、木香、玫瑰花、桂花、苏合香。
2.根据权利要求1所述的芳香中草药组合物,其特征在于,包含以下重量份数的各组分:白芷3~7份、丁香4~6份、艾叶3~7份、小茴香4~6份、山柰3~7份、肉桂8~12份、当归8~12份、川芎8~12份、香附8~12份、木香8~12份、玫瑰花13~17份、桂花14~16份、苏合香0.05~0.15份。
3.根据权利要求1所述的芳香中草药组合物,其特征在于,包含以下重量份数的各组分:白芷4~6份、丁香4~6份、艾叶4~6份、小茴香4~6份、山柰4~6份、肉桂9~11份、当归9~11份、川芎9~11份、香附9~11份、木香9~11份、玫瑰花14~16份、桂花14~16份、苏合香0.08~0.12份。
4.根据权利要求1所述的芳香中草药组合物,其特征在于,包含以下重量份数的各组分:白芷5~6份、丁香5~6份、艾叶5~6份、小茴香5~6份、山柰5~6份、肉桂10~11份、当归10~11份、川芎10~11份、香附10~11份、木香10~11份、玫瑰花15~16份、桂花15~16份、苏合香0.1~0.12份。
5.根据权利要求1所述的芳香中草药组合物,其特征在于,包含以下重量份数的各组分:白芷5~6份、丁香5~6份、艾叶5~6份、小茴香5~6份、山柰5~6份、肉桂10~11份、当归10~11份、川芎10~11份、香附10~11份、木香10~11份、玫瑰花15份、桂花15份、苏合香0.1份。
6.根据权利要求1所述的芳香中草药组合物,其特征在于,包含以下重量份数的各组分:白芷5~6份、丁香5~6份、艾叶5~6份、小茴香5~6份、山柰5~6份、肉桂10份、当归10份、川芎10份、香附10份、木香10份、玫瑰花15份、桂花15份、苏合香0.1份。
7.权利要求1~6任一所述缓解痛经的芳香中草药组合物的制备方法,其特征在于,分别取白芷、丁香、艾叶、小茴香、山柰、肉桂、当归、川芎、香附、木香、玫瑰花、桂花、苏合香研磨成粉,称取相应重量份数的中草药粉末混合。
8.权利要求1~6任一项所述芳香中草药组合物在制备缓解痛经的芳香疗法产品中的应用。
9.根据权利要求8所述应用,其特征在于,所述痛经为寒凝血瘀型痛经。
10.一种用于缓解痛经的芳香疗法产品,其特征在于,所述产品含有权利要求1~6任一项所述的芳香中草药组合物。
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