CN117122654A - Traditional Chinese medicine prescription for treating thromboangiitis obliterans - Google Patents
Traditional Chinese medicine prescription for treating thromboangiitis obliterans Download PDFInfo
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- CN117122654A CN117122654A CN202310892892.XA CN202310892892A CN117122654A CN 117122654 A CN117122654 A CN 117122654A CN 202310892892 A CN202310892892 A CN 202310892892A CN 117122654 A CN117122654 A CN 117122654A
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of traditional Chinese medicine formulas, and discloses a traditional Chinese medicine formula for treating thromboangiitis obliterans. The composition is prepared from the following components in parts by weight: main medicine: 60-120 parts of angelica sinensis, 60-120 parts of radix scrophulariae, 60-120 parts of radix astragali, 30-60 parts of achyranthes bidentata, 60-120 parts of liquorice and 60-120 parts of honeysuckle; dispensing: 60-120 parts of coix seed, 10-20 parts of frankincense, 10-20 parts of myrrh, 10-20 parts of radix angelicae, 6-12 parts of safflower, 15-30 parts of magnolia officinalis, 15-30 parts of chaenomeles speciosa, 15-30 parts of lycopodium clavatum and 30-60 parts of white sugar ginseng. Decocting with water, and taking 1 dose every 1 day, wherein the dose is divided into 2 times of administration in the morning and evening, and the treatment time is 2 months. The formula has low cost and good curative effect, and the components are in interaction coordination, so that the Chinese medicinal composition has the effects of enriching blood and activating blood, relaxing tendons and activating collaterals, dispelling wind and dispelling cold, removing dampness and detumescence, clearing heat and detoxicating and relieving pain.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine formulas, and particularly relates to a traditional Chinese medicine formula for treating thromboangiitis obliterans.
Background
Vasculitis is a type of ischemic disease of the arteries of the lower extremities, mainly arteritis, phlebitis or inflammation of the lymphatic vessel walls. Pain, ulcers, and even gangrene may occur when an ischemic limb develops. The early onset of disease is only manifested by low limb temperature, cold feeling, and muscle soreness after walking. When ulcer, necrosis and gangrene occur seriously in the ischemia of the lower limb, if the optimal treatment period is not held, the treatment is delayed, the possibility of rescuing the limb is easily lost, and finally amputation is caused. Patients suffering from vasculitis are most faced with amputation problems due to the lack of previous treatments. With the development of scientific technology, more and more new technologies are applied to clinic, and the current amputation rate has been reduced. If the disease of the patient can be found and treated early, the effective medicine is utilized for symptomatic treatment, which is beneficial to avoiding amputation of the vasculitis patient. The amputation causes not only low curative effect but also great pain to the patient and great trouble to the normal life of the patient and the family.
The pathological mechanism and the treatment scheme of the disease are still not clear, the curative effect is poor after the treatment, the disease can be repeatedly caused, and the disease is clinically treated by anticoagulation, anti-inflammatory and fiber reduction. Although the medicine can relieve symptoms, the cause of the disease cannot be fundamentally eliminated, side effects can also appear after treatment, and long-term administration cannot be realized; the efficacy of surgical treatment is better, but occlusion occurs again after a period of time, and thus there is still a need to explore the best therapeutic regimen that can be accepted by patients.
The traditional Chinese medicine considers that the etiology is deficiency of qi and blood and incoordination of yin and yang, and the treatment is started by clearing heat, detoxicating, promoting blood circulation and removing blood stasis. Along with the continuous perfection of modern traditional Chinese medicine, many doctors excavate relevant records in the ancient classical medical centralization, and the key points of cold, stasis, dampness, heat, toxin and deficiency as pathogenicity are also provided by combining with own clinical experience. Reasonable formula and the like from the aspects of warming yang, dispelling cold, promoting blood circulation, eliminating dampness, detoxifying, tonifying deficiency and the like, and the traditional Chinese medicine has a certain curative effect on treating thromboangiitis obliterans.
The four wonderful branchlet's an soup is an experienced good prescription for treating heat-toxicity gangrene, and is composed of four medicines of honeysuckle, figwort, angelica and liquorice, and has the functions of clearing heat and detoxicating, nourishing yin and cooling blood, activating blood and removing obstruction in channels and relieving pain. The prescription has effects of promoting blood circulation, relieving pain, replenishing blood, promoting tissue regeneration, etc., and can effectively improve vascular function of patient and limb function.
CN111057C reports a medicine for treating vasculitis, which is prepared from ginseng, astragalus root, honeysuckle flower, chinese angelica root, figwort root and licorice root through removing impurities, cleaning, drying, grinding into powder, and then processing into watered pills. Meanwhile, the invention respectively adds the menstruation guiding medicine to the upper and lower different parts of the affected limb, and adds turmeric to the affected body; for patients with lower body, adding Achyranthis radix; radix Aconiti lateralis Preparata for cold syndrome and cortex Phellodendri for heat syndrome are added.
CN1159943a reports a medicine for treating thromboangiitis obliterans, which is prepared from radix astragali, radix Platycodi, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, poria, polyporus, rhizoma Atractylodis, zingiberis rhizoma, radix Aconiti lateralis Preparata, ramulus Cinnamomi, semen Persicae, carthami flos, scolopendra, herba Taraxaci, herba Violae, olibanum, myrrha, realgar, and Glycyrrhrizae radix by oven drying, grinding into powder, and making into honeyed pill for administration.
Traditional Chinese medicine for treating vasculitis has more reports and different treatment effects. The traditional Chinese medicines such as salvia miltiorrhiza ligustrazine, vascular rehabilitation tablet, four second Yongan soup, yang harmonizing soup and the like can be used for relieving symptoms in a short period, but the long-term curative effect is uncertain. Therefore, a traditional Chinese medicine prescription with good long-term curative effect and difficult recurrence needs to be explored.
Disclosure of Invention
Aiming at the practical problem that the existing vasculitis is difficult to treat, the invention aims to provide a traditional Chinese medicine formula for treating vasculitis, which has the advantages of simplified formula, good long-term curative effect and difficult recurrence.
In order to achieve the purpose of the invention, the technical scheme adopted by the invention is as follows:
the traditional Chinese medicine formula for treating vasculitis is prepared from the following components in parts by weight:
main medicine: 60-120 parts of angelica sinensis, 60-120 parts of radix scrophulariae, 60-120 parts of radix astragali, 30-60 parts of achyranthes bidentata, 60-120 parts of liquorice and 60-120 parts of honeysuckle; dispensing: 60-120 parts of coix seed, 10-20 parts of frankincense, 10-20 parts of myrrh, 10-20 parts of radix angelicae, 6-12 parts of safflower, 15-30 parts of magnolia officinalis, 15-30 parts of chaenomeles speciosa, 15-30 parts of lycopodium clavatum and 30-60 parts of white sugar ginseng.
Preferably: the components are calculated according to parts by weight: main medicine: 60 parts of Chinese angelica, 60 parts of radix scrophulariae, 60 parts of radix astragali, 30 parts of achyranthes root, 60 parts of liquorice and 60 parts of honeysuckle; dispensing: 60 parts of coix seed, 10 parts of frankincense, 10 parts of myrrh, 10 parts of radix angelicae, 6 parts of safflower, 15 parts of magnolia officinalis, 15 parts of chaenomeles sinensis, 15 parts of lycopodium clavatum and 30 parts of white sugar ginseng.
The Chinese angelica is a 'qi-flowing medicine in blood, is also a holy medicine in blood', is suitable for people with liver and spleen two meridians, has the effects of replenishing blood and activating blood, regulating menstruation and relieving pain, moistening dryness and lubricating intestines, and is used for treating blood deficiency and sallow complexion, dizziness and palpitation, irregular menstruation, amenorrhea and dysmenorrhea, deficiency-cold abdominal pain, rheumatalgia, traumatic injury, carbuncle and sore; radix scrophulariae has effects of clearing heat and cooling blood, nourishing yin and lowering fire, removing toxic substance and resolving hard mass, and can be used for treating heat entering nutrient blood, and treating toxic heat, macula, carbuncle, swelling and sore; astragalus mongholicus has the effects of clearing heat and cooling blood, purging pathogenic fire and removing toxin and nourishing yin, and is mainly used for treating carbuncle and sore toxin caused by toxic heat; the achyranthes root has the effects of activating blood circulation to promote menstruation, tonifying liver and kidney, strengthening tendons and bones, inducing diuresis to treat stranguria and guiding blood to descend, and is mainly used for treating traumatic injury pain, soreness of waist and knees and weakness of lower limbs; licorice has the effects of invigorating spleen and replenishing qi, clearing heat and detoxicating, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing various medicines, and the discrimination rights are as follows: licorice is a monarch drug in the medicines, and is used for treating seventy-two opalescent toxins, resolving one thousand of two hundred-way herb toxins and harmonizing the active ingredients of the medicines, so that the medicines are of old national grade; the flos Lonicerae has effects of clearing heat and detoxicating, cooling and dispelling pathogenic wind and heat, and can be used for treating carbuncle, furuncle, erysipelas, and dysentery due to heat and blood; the coix seed has the effects of promoting diuresis, strengthening spleen, removing arthralgia, clearing heat and expelling pus; the olibanum has the effects of regulating qi and activating blood, relieving pain, expelling toxin, and treating carbuncle, sore and swelling; myrrh has the effects of dispelling blood stasis, relieving swelling and pain; radix Angelicae Dahuricae has effects of dispelling pathogenic wind and dampness, promoting blood circulation, expelling pus, promoting granulation, and relieving pain; safflower nature is pungent, has the effects of dredging channels, activating blood circulation, removing blood stasis and relieving pain; chuan papaya has the functions of calming liver, harmonizing stomach, dehumidifying, relaxing tendons and the like; the lycopodium clavatum has bitter and pungent taste and warm nature, enters liver meridian, and has the effects of dispelling wind and cold, removing dampness and detumescence, and relaxing tendons and activating collaterals; white sugar has sweet taste, slightly bitter taste, slightly warm taste, and has effects of invigorating primordial qi, invigorating spleen, benefiting lung, promoting salivation, quenching thirst, tranquilizing mind, and improving intelligence.
The pharmacology of the invention: arteries and veins are the main vasculature of the human body, are the channels of human life, and are closely related to human life activities. The functions of arteries and veins are quite different, and arteries are used for conveying arterial blood of a human body to tissues and capillaries of the whole body; the veins, on the contrary, return the tissue, venous blood in capillaries, i.e. metabolic waste of the tissue, to the heart and pulmonary arteries and to the liver for nutrient exchange. Based on pharmacopoeia and modern clinical experience, the invention takes Chinese angelica, figwort root, astragalus root, achyranthes root, liquorice and honeysuckle as main medicines, and coix seed, frankincense, myrrh, angelica dahurica, safflower, magnolia bark, common floweringquince fruit, lycopodium clavatum and white sugar as auxiliary medicines, and the components exert synergistic effect through blending, thus achieving the effects of activating blood circulation, relieving pain, enriching blood, promoting tissue regeneration, effectively improving the vascular function of patients and improving the limb functions of the patients.
The using method comprises the following steps: the preparation is decocted in water for 1 day and 1 dose, and is divided into 2 times of administration in the morning and evening, and the treatment time is 2 months.
80 vasculitis patients were selected as clinical treatment observations and randomized into 2 groups, with treatment group 40 and control group 40. The treatment group uses the prescription of the invention, and 2 months is a treatment course. The control group took aspirin as required. The selected patients had the following symptoms: ischemia, pain, swelling of the affected limb. The results of the two groups of clinical symptoms were as follows:
| group of | The number of people | Has obvious effect | Effective and effective | Invalidation of | The total effective rate is% |
| Treatment group | 40 | 30 | 10 | 0 | 100 |
| Control group | 40 | 22 | 13 | 5 | 87.5 |
Standard of efficacy: the effect is shown: the local skin swelling of clinical symptoms is obviously disappeared; the method is effective: clinical symptoms of localized skin mild swelling are reduced; invalidation: there was no change in clinical symptoms.
Total effective rate= (number of cured cases + number of significant cases + number of effective cases)/total number of cases x 100%.
The beneficial effects of the invention are as follows:
the invention relates to a traditional Chinese medicine compound for treating thromboangiitis obliterans, which has the treatment effects of improving skin swelling and relieving pain. The traditional Chinese medicines used in the prescription can be mutually compatible, the prescription contains rich medicinal effect component groups, and the Chinese angelica and the honeysuckle are taken together, so that the hypersensitivity protein and tumor necrosis factor in serum can be reducedαThe level of the method reduces the probability of infection of inflammatory cells on the arterial wall, protects the vascular wall and can prevent early arterial tumor cells from growing; the honeysuckle and the liquorice can be taken together for treating dermatitis; the Chinese angelica and the liquorice are used together, so that the Chinese angelica and the liquorice have special curative effects on dermatitis caused by blood deficiency and cold coagulation; safflower and dahurian angelica root can promote blood circulation and promote menstruation; the white sugar has effects of invigorating primordial qi, promoting salivation, quenching thirst, tranquilizing mind, and improving intelligence. Therefore, the traditional Chinese medicines exert the efficacy cooperatively to treat the thromboangiitis obliterans, and have the advantages of low cost, good curative effect, capability of relieving disease symptoms, detumescence, analgesia, no toxic or side effect and convenient use. After the medicine is used by patients, the cure rate reaches 100 percent. The follow-up visit after healing shows that the medicine does not relapse after healing, has no drug resistance and no drug resistance, and is applicable to thromboangiitis obliterans patients.
Detailed Description
The invention will be further explained with reference to specific examples.
Example 1:
the traditional Chinese medicine prescription for treating thromboangiitis obliterans is prepared from the following components in parts by weight: 60 parts of Chinese angelica, 60 parts of radix scrophulariae, 60 parts of radix astragali, 30 parts of achyranthes bidentata, 60 parts of liquorice, 60 parts of honeysuckle, 60 parts of coix seed, 10 parts of frankincense, 10 parts of myrrh, 10 parts of radix angelicae, 6 parts of safflower, 15 parts of magnolia officinalis, 15 parts of chaenomeles sinensis, 15 parts of lycopodium clavatum and 30 parts of white sugar ginseng.
Example 2:
the prescription for treating thromboangiitis obliterans is prepared from the following components in parts by weight: 120 parts of Chinese angelica, 120 parts of radix scrophulariae, 120 parts of radix astragali, 60 parts of achyranthes bidentata, 120 parts of liquorice, 120 parts of honeysuckle, 120 parts of coix seed, 20 parts of frankincense, 20 parts of myrrh, 20 parts of radix angelicae, 12 parts of safflower, 30 parts of magnolia officinalis, 30 parts of chaenomeles sinensis, 30 parts of lycopodium clavatum and 60 parts of white sugar ginseng.
Example 3:
the prescription for treating thromboangiitis obliterans is prepared from the following components in parts by weight: 90 parts of Chinese angelica, 90 parts of radix scrophulariae, 90 parts of radix astragali, 45 parts of achyranthes bidentata, 90 parts of liquorice, 90 parts of honeysuckle, 90 parts of pearl barley, 15 parts of frankincense, 15 parts of myrrh, 15 parts of radix angelicae, 9 parts of safflower, 20 parts of magnolia officinalis, 20 parts of chaenomeles sinensis, 20 parts of lycopodium clavatum and 45 parts of white sugar ginseng.
Typical case one:
mr. Hou, man, age 40, symptoms were intermittent pain, coolness and numbness in extremities, diagnostic opinion: vasculitis.
Two diagnoses: the patient is checked again after 2 months of the prescription of the invention, the symptoms disappear, the pain is not caused, and the walking is recovered to be normal.
Typical case two:
mr. King, men, 28 years old, were examined in hospitals for lower limb pain, and patients had massive thrombosis in the vessel lumen with fibrosis of the vessel wall, diagnostic opinion: vasculitis.
Two diagnoses: the patient is checked after 2 months of the prescription of the invention, and the result is that: pain sensation of lower limbs disappears, focus disappears and walking is normal.
The traditional Chinese medicine for treating vasculitis can effectively control and improve the disease condition of vasculitis patients in the process of treating vasculitis, and the vasculitis patients recover after taking the traditional Chinese medicine for 2 months.
The invention is not limited to the alternative embodiments described above, but any person may derive other various forms of products in the light of the present invention. The above detailed description should not be construed as limiting the scope of the invention, which is defined in the claims and the description may be used to interpret the claims.
Claims (2)
1. The traditional Chinese medicine prescription for treating thromboangiitis obliterans is prepared by the following components in a compatibility manner, and is characterized in that: the components are calculated according to parts by weight: main medicine: 60-120 parts of angelica sinensis, 60-120 parts of radix scrophulariae, 60-120 parts of radix astragali, 30-60 parts of achyranthes bidentata, 60-120 parts of liquorice and 60-120 parts of honeysuckle; dispensing: 60-120 parts of coix seed, 10-20 parts of frankincense, 10-20 parts of myrrh, 10-20 parts of radix angelicae, 6-12 parts of safflower, 15-30 parts of magnolia officinalis, 15-30 parts of chaenomeles speciosa, 15-30 parts of lycopodium clavatum and 30-60 parts of white sugar ginseng.
2. The traditional Chinese medicine prescription for treating thromboangiitis obliterans according to claim 1, which is prepared by the following components in a compatibility way, and is characterized in that: the components are calculated according to parts by weight: main medicine: 60 parts of Chinese angelica, 60 parts of radix scrophulariae, 60 parts of radix astragali, 30 parts of achyranthes root, 60 parts of liquorice and 60 parts of honeysuckle; dispensing: 60 parts of coix seed, 10 parts of frankincense, 10 parts of myrrh, 10 parts of radix angelicae, 6 parts of safflower, 15 parts of magnolia officinalis, 15 parts of chaenomeles sinensis, 15 parts of lycopodium clavatum and 30 parts of white sugar ginseng.
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