CN117084617A - Endoscope tip assembly in small diameter endoscopes using a truncated trapezoidal cavity inserter to allow camera and LED to be coplanar - Google Patents

Endoscope tip assembly in small diameter endoscopes using a truncated trapezoidal cavity inserter to allow camera and LED to be coplanar Download PDF

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CN117084617A
CN117084617A CN202310567858.5A CN202310567858A CN117084617A CN 117084617 A CN117084617 A CN 117084617A CN 202310567858 A CN202310567858 A CN 202310567858A CN 117084617 A CN117084617 A CN 117084617A
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led
cavity
level
bond pad
inserter
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陈腾盛
陈伟平
林蔚峰
邓兆展
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Omnivision Technologies Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0661Endoscope light sources
    • A61B1/0684Endoscope light sources using light emitting diodes [LED]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064Constructional details of the endoscope body
    • A61B1/00071Insertion part of the endoscope body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00131Accessories for endoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/00234Surgical instruments, devices or methods for minimally invasive surgery

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  • Surgery (AREA)
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  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
  • Endoscopes (AREA)

Abstract

The present invention relates to a cavity interposer having a cavity, a first bond pad disposed within a base of the cavity adapted to be coupled to a chip camera cube at a first level, the first bond pad being coupled to a second bond pad at a second level at the base of the interposer through a feedthrough; and a third bond pad adapted to be coupled to a Light Emitting Diode (LED) at a third level. The third bond pad is coupled to a fourth bond pad at the second level at the base of the interposer; and the second bond pad and the fourth bond pad are coupled to conductors of the cable, wherein the first level, the second level, and the third level are different. The endoscope optics includes a cavity interposer, an LED, and a chip camera cube electrically bonded to the first bond pad; the LED is bonded to the third bond pad; and the top of the chip camera cube and the top of the LED are at the same level.

Description

小直径内窥镜中的使用截断梯形腔插入器以允许相机和LED 共面的内窥镜尖端组件Use of truncated trapezoidal cavity inserter in small diameter endoscopes to allow camera and LED Coplanar endoscope tip assembly

相关申请Related applications

本文件是2021年10月18日提交的美国专利申请17/504,105的部分继续申请。前述专利申请的全部内容以引用的方式并入到本文中。This document is a continuation-in-part of U.S. patent application 17/504,105 filed on October 18, 2021. The entire contents of the aforementioned patent applications are incorporated herein by reference.

背景技术Background technique

内窥镜在医学中已变得普遍,用于检查组织或观察和引导外科手术,而无需做出大切口以便肉眼可以看见这些组织,并且类似装置通常用于在机械装置的精密位置中进行检查,以避免需要拆卸。典型地,内窥镜的远侧端部被插入精密位置中或身体中,医生或其他使用者观察通过内窥镜的近侧端部附近的显示设备显示的图像。Endoscopes have become common in medicine, used to examine tissues or to observe and guide surgical procedures without making large incisions so that the tissues can be seen with the naked eye, and similar devices are often used to perform inspections in delicate locations on mechanical devices to avoid the need for disassembly. Typically, the distal end of the endoscope is inserted into a precise location or body, and a physician or other user views images displayed by a display device near the proximal end of the endoscope.

过去的内窥镜通常具有带有透镜的相机,该透镜将光聚焦到内窥镜的远侧端部处的相干光纤束的端部上,并将来自外部照明器的光通过光纤引导到位于透镜前方的待检查组织或部分上;光纤将来自内窥镜的远侧端部的图像带到内窥镜的近侧端部附近的显示设备。Endoscopes of the past typically had a camera with a lens that focused light onto the end of a coherent fiber optic bundle at the distal end of the endoscope and directed light from an external illuminator through the fiber optic cable to the end of the optical fiber bundle located at the distal end of the endoscope. On the tissue or section to be examined in front of the lens; fiber optics carry images from the distal end of the endoscope to a display device near the proximal end of the endoscope.

随着电子相机变得越来越小,存在将诸如发光二极管(LED)或激光二极管的光源和电子相机放置在内窥镜的远侧端部处并将来自电子相机的信号传输到内窥镜的近侧端部附近的显示设备的增加趋势。As electronic cameras become smaller and smaller, it is possible to place a light source such as a light emitting diode (LED) or a laser diode and the electronic camera at the distal end of the endoscope and transmit the signal from the electronic camera to the endoscope The proximal end near the display device increases the trend.

芯片型电子相机在手机和类似装置中已经变得很普遍。它们通过以下方式以晶片级形成:将图像传感器集成电路的晶片键合到间隔件晶片,并将透镜的晶片键合到间隔件晶片,使得透镜定位在每个图像传感器的前方并与每个图像传感器以焦距间隔开。然后通过锯切将复合晶片切割成单独的相机,并且然后将相机表面安装到衬底。Chip-based electronic cameras have become common in cell phones and similar devices. They are formed at the wafer level by bonding the wafer of the image sensor integrated circuit to the spacer wafer and the wafer of the lens to the spacer wafer such that the lens is positioned in front of each image sensor and in conjunction with each image sensor. The sensors are spaced apart by focal length. The composite wafer is then cut into individual cameras by sawing, and the cameras are then surface mounted to the substrate.

如果LED和芯片型电子相机被表面安装在内窥镜的远侧端部处的单个平坦衬底上,由于LED比芯片型电子相机薄得多,相机可能遮蔽内窥镜的远侧端部前面的部分视场。If the LED and chip-based electronic camera are surface mounted on a single flat substrate at the distal end of the endoscope, since the LED is much thinner than the chip-based electronic camera, the camera may obscure the front of the distal end of the endoscope part of the field of view.

发明内容Contents of the invention

在一个实施例中,腔插入器具有腔、布置在腔的基部内的在第一层级处适于耦接到芯片型相机立方体的第一键合焊盘,第一键合焊盘通过馈通耦接到插入器的基部处的在第二层级处的第二键合焊盘;以及第三键合焊盘,第三键合焊盘适于耦接到发光二极管(LED),第三键合焊盘处于第三层级处。第三键合焊盘耦接到插入器的基部处的在第二层级处的第四键合焊盘;并且第二键合焊盘和第四键合焊盘耦接到电缆的导体,其中第一层级、第二层级和第三层级不同。在实施例中,内窥镜光学件(endoscope optical)包括腔插入器、LED和电键合到第一键合焊盘的芯片型相机立方体;LED键合到第三键合焊盘;并且芯片型相机立方体的顶部和LED的顶部在同一层级处。In one embodiment, the cavity interposer has a cavity, a first bonding pad disposed within a base of the cavity at a first level adapted to be coupled to the camera-on-a-chip cube, the first bonding pad passing through a feedthrough a second bonding pad at a second level coupled to the base of the interposer; and a third bonding pad adapted to be coupled to a light emitting diode (LED), the third bond The bonding pad is at the third level. The third bonding pad is coupled to the fourth bonding pad at the second level at the base of the interposer; and the second and fourth bonding pads are coupled to the conductors of the cable, wherein The first level, the second level and the third level are different. In an embodiment, an endoscope optical includes a cavity inserter, an LED, and a chip-type camera cube electrically bonded to a first bonding pad; the LED is bonded to a third bonding pad; and the chip-type camera cube The top of the camera cube and the top of the LED are at the same level.

附图说明Description of the drawings

在附图中,第一附图和第二附图中的相同附图标记指示具有与第一附图和第二附图中所图示的基本相同的描述和功能的结构。In the drawings, like reference numerals in the first and second figures indicate structures having substantially the same description and function as illustrated in the first and second figures.

图1A是腔插入器的截面的示意图,腔插入器是允许以与相邻LED在同一层级处表面安装带有透镜的相机的衬底。Figure 1A is a schematic illustration of a cross-section of a cavity interposer, a substrate that allows surface mounting of a camera with a lens at the same level as adjacent LEDs.

图1B是由两个层状部分形成的腔插入器的截面的示意图。Figure IB is a schematic illustration of a cross-section of a cavity inserter formed from two layered portions.

图2是光学内窥镜头部的示意图,该光学内窥镜头部包括图1A、图1B的腔插入器。FIG. 2 is a schematic diagram of an optical endoscope head unit including the cavity inserter of FIGS. 1A and 1B .

图3是腔插入器的可选实施例的示意性截面图,示出了附接的LED。Figure 3 is a schematic cross-sectional view of an alternative embodiment of a cavity inserter showing attached LEDs.

图4是圆形光学内窥镜头部的俯视图,示出了安装的LED和相机立方体。Figure 4 is a top view of the circular optical endoscope head showing the mounted LED and camera cube.

图5是矩形光学内窥镜头部的俯视图,示出了安装的LED和相机立方体。Figure 5 is a top view of a rectangular optical endoscope head showing the mounted LED and camera cube.

图6是结合了图4的光学内窥镜头部的内窥镜的端视图。6 is an end view of an endoscope incorporating the optical endoscope head portion of FIG. 4 .

图7是结合了图2或图4的光学内窥镜头部的内窥镜的截面的示意图。7 is a schematic diagram of a cross-section of an endoscope incorporating the optical endoscope head portion of FIG. 2 or 4 .

图8是被配置用于在小直径内窥镜中使用的具有截断梯形形状的腔插入器的示意性俯视平面图。Figure 8 is a schematic top plan view of a lumen inserter having a truncated trapezoidal shape configured for use in a small diameter endoscope.

图9是源自图8的腔插入器的示意性俯视平面图,该腔插入器具有边缘,盖子可以密封到该边缘,或者该边缘可以用透明塑料材料填充。Figure 9 is a schematic top plan view of a cavity inserter derived from Figure 8 having a rim to which a lid may be sealed or which may be filled with a transparent plastic material.

具体实施方式Detailed ways

腔插入器100(图1A)包括衬底102,衬底102具有馈通导体104、110,该馈通导体104、110将适于球键合安装发光二极管的的键合焊盘108、114连接到适于附接到连接电缆的导体的键合焊盘108、114。插入器100具有适于容纳芯片型“相机立方体”的腔115,该腔115具有适于球键合以安装芯片型相机立方体的键合焊盘118、122(如图2所示)。键合焊盘118、122通过导电馈通116、124耦接到腔插入器100的基部125处的键合焊盘120、126,键合焊盘120、126适于单独附接到连接电缆的导体。该电缆可以具有少至五个导体,尽管许多实施例,包括那些具有荧光刺激LED(见下文)的实施例,可以具有多于五个导体。Cavity interposer 100 (FIG. 1A) includes a substrate 102 having feedthrough conductors 104, 110 connecting bond pads 108, 114 suitable for ball bonding mounted light emitting diodes. to bonding pads 108, 114 adapted to be attached to the conductors of the connecting cable. The interposer 100 has a cavity 115 adapted to receive a "camera cube-on-a-chip" with bonding pads 118, 122 suitable for ball bonding to mount the camera-on-a-chip cube (as shown in Figure 2). Bond pads 118, 122 are coupled to bond pads 120, 126 at the base 125 of the cavity interposer 100 by conductive feedthroughs 116, 124, the bond pads 120, 126 being adapted to be separately attached to the connection cables. conductor. The cable may have as few as five conductors, although many embodiments, including those with fluorescent stimulation LEDs (see below), may have more than five conductors.

在一个实施例中,腔插入器100被组装到内窥镜光学头部组件200(图2)中,其中相机立方体202定位在腔115中,并且相机立方体202的键合焊盘被键合到键合焊盘118、122。光学头部组件还包括至少一个发光二极管(LED)204,该至少一个发光二极管(LED)204键合到键合焊盘108、114并被配置成照亮可由相机立方体202成像的视场内的物体,在特定实施例中,LED 204是白光LED。内窥镜光学头部组件200还具有透明保护窗口205,该透明保护窗口205用防水材料密封并且被定位成保护相机立方体202和LED 204;为了将透明保护窗口205支撑在相机立方体202和LED 204上方,腔插入器在一些实施例中可以具有边缘216来支撑透明保护窗口205。相机立方体202包括成像透镜203和图像传感器208,以及间隔件(图2中未示出),该间隔件在成像透镜203与图像传感器208之间提供足够的空间以将视场内的物体的图像聚焦到图像传感器208上。典型地,图像传感器208包括颜色滤光器阵列214,该颜色滤光器阵列214具有颜色滤光器的拼接图案(tiling pattern),诸如贝尔图案拼接图案,该颜色滤光器阵列包括红色、绿色和蓝色带通滤光器以提供全色图像。相机立方体202被配置成典型地在其下表面上具有焊料凸块,用于键合到腔插入器100的键合焊盘118、122,并且在一个实施例中,该相机立方体202被球焊键合到腔插入器100的键合焊盘118、122。在可选实施例中,相机立方体202的键合焊盘用导电的含银胶或各向异性导电膜电键合到腔插入器100的键合焊盘118、122。在内窥镜光学头部中,腔插入器100的下表面的键合焊盘106、112、120、126附接到柔性衬底210上形成的导体209,以形成柔性内窥镜电缆212。在一个实施例中,相机立方体202的顶部与LED 204的顶部处于同一层级。In one embodiment, cavity inserter 100 is assembled into endoscopic optical head assembly 200 (FIG. 2) with camera cube 202 positioned in cavity 115 and the bonding pads of camera cube 202 bonded to Bonding pads 118, 122. The optical head assembly also includes at least one light emitting diode (LED) 204 bonded to the bond pads 108 , 114 and configured to illuminate the field of view imageable by the camera cube 202 Object, in particular embodiments, LED 204 is a white light LED. The endoscope optical head assembly 200 also has a transparent protective window 205 that is sealed with a waterproof material and positioned to protect the camera cube 202 and the LED 204; in order to support the transparent protective window 205 on the camera cube 202 and the LED 204 Above, the cavity inserter may have an edge 216 in some embodiments to support a transparent protective window 205 . Camera cube 202 includes imaging lens 203 and image sensor 208, as well as a spacer (not shown in Figure 2) that provides sufficient space between imaging lens 203 and image sensor 208 to image objects within the field of view. Focus on image sensor 208. Typically, the image sensor 208 includes a color filter array 214 having a tiling pattern of color filters, such as a Bell pattern tiling pattern, including red, green and blue bandpass filters to provide full color images. The camera cube 202 is configured typically with solder bumps on its lower surface for bonding to the bonding pads 118 , 122 of the cavity interposer 100 , and in one embodiment, the camera cube 202 is ball-bonded Bonded to the bond pads 118, 122 of the cavity interposer 100. In an alternative embodiment, the bond pads of the camera cube 202 are electrically bonded to the bond pads 118, 122 of the cavity interposer 100 using a conductive silver-containing glue or anisotropic conductive film. In the endoscope optical head, bonding pads 106 , 112 , 120 , 126 on the lower surface of the cavity inserter 100 are attached to conductors 209 formed on the flexible substrate 210 to form a flexible endoscope cable 212 . In one embodiment, the top of camera cube 202 is at the same level as the top of LED 204.

在特定实施例中,腔插入器由两个衬底材料晶片组装而成,下部部分164(图1B)形成有多个下部腔插入器部分,多个下部腔插入器部分具有馈通116、124、160、162和适当的键合焊盘120、112、126,并且上部部分170形成有多个腔插入器部分,其内形成腔115。上部部分170形成有馈通172、174,馈通172、174与下部部分164的馈通160、162对准以形成长馈通104、110,长馈通104、110到达LED将被键合的层级(level,也可称为水平或高度),并且到达用于LED的键合焊盘108、114,而馈通124到达适于附接相机立方体202(图2)的键合焊盘122、118。然后将两个晶片键合在一起,使得下部部分的馈通160、162电连接到上部部分的对准的馈通172、174,并且腔115处于正确的位置,然后将晶片切割以形成腔插入器。在可选实施例中,在晶片被切割以形成光学头部组件之前,相机立方体202和LED 204被键合到腔115中并键合到腔插入器的键合焊盘。In certain embodiments, the cavity interposer is assembled from two wafers of substrate material, with lower portion 164 (FIG. 1B) formed with a plurality of lower cavity interposer portions having feedthroughs 116, 124 , 160, 162 and appropriate bonding pads 120, 112, 126, and the upper portion 170 is formed with a plurality of cavity interposer portions with cavities 115 formed therein. The upper portion 170 is formed with feedthroughs 172 , 174 that are aligned with the feedthroughs 160 , 162 of the lower portion 164 to form long feedthroughs 104 , 110 that reach where the LEDs will be bonded. level (also referred to as level or height) and reaches bonding pads 108, 114 for the LEDs, while feedthrough 124 reaches bonding pads 122, 122 suitable for attaching the camera cube 202 (FIG. 2) 118. The two wafers are then bonded together so that the lower portion's feedthroughs 160, 162 are electrically connected to the upper portion's aligned feedthroughs 172, 174 and the cavity 115 is in the correct position, and the wafer is then cut to form the cavity insert device. In an alternative embodiment, the camera cube 202 and LED 204 are bonded into the cavity 115 and to the bond pads of the cavity interposer before the wafer is diced to form the optical head assembly.

在具有边缘216的实施例中,边缘可以形成为第三晶片,并且在切割晶片之前键合到具有腔插入器的上部部分的晶片。在这些实施例中的部分实施例中,在切割晶片之前,透明盖(未示出)附接在边缘之上。在可选实施例中,替代在照相机立方体和LED上密封透明盖的是,将透明塑料材料注入到由边缘形成的腔中并用于覆盖和保护相机立方体和LED二者。透明盖和透明塑料材料二者都用于保护相机立方体、LED和存在于由边缘形成的腔内的任何键合线的保护。In embodiments with edge 216, the edge may be formed as a third wafer and bonded to the wafer with the upper portion of the cavity inserter prior to cutting the wafer. In some of these embodiments, a transparent cover (not shown) is attached over the edge before dicing the wafer. In an alternative embodiment, instead of sealing a transparent cover over the camera cube and LED, a transparent plastic material is injected into the cavity formed by the edges and serves to cover and protect both the camera cube and LED. The clear cover and clear plastic material both serve to protect the camera cube, the LEDs, and any bonding wires present within the cavity formed by the edges.

在实施例中,腔插入器100是多层陶瓷结构,其中在层被烧制在一起之前,腔115形成在一层或多层中。在可选实施例中,腔插入器100由诸如注射模制塑料或印刷电路板材料的复合材料形成,在此可选实施例中,用于馈通116、124、104、110的孔可以通过激光钻孔形成,并且腔115可以通过机械钻孔形成;在腔插入器由印刷电路板材料形成的实施例中,腔插入器可以由一层或多层绝缘材料、两层或三层导电材料以及一层或多层绝缘支撑材料形成。一旦形成,在一些实施例中用于馈通的孔被镀通以形成馈通116、124、104、110,并且在其他实施例中,馈通116、124、104、110通过化学气相沉积(CVD)或蒸发金属沉积形成。In an embodiment, cavity inserter 100 is a multi-layer ceramic structure in which cavity 115 is formed in one or more layers before the layers are fired together. In an alternative embodiment, the cavity inserter 100 is formed from a composite material such as injection molded plastic or a printed circuit board material, in which the holes for the feedthroughs 116, 124, 104, 110 may be passed through Laser drilling is formed, and the cavity 115 can be formed by mechanical drilling; in embodiments where the cavity interposer is formed from a printed circuit board material, the cavity interposer can be formed from one or more layers of insulating material, two or three layers of conductive material and one or more layers of insulating support material are formed. Once formed, in some embodiments the holes for the feedthroughs are plated through to form the feedthroughs 116, 124, 104, 110, and in other embodiments the feedthroughs 116, 124, 104, 110 are deposited by chemical vapor deposition ( CVD) or evaporated metal deposition.

在一个实施例中,柔性衬底210由柔性印刷电路材料形成,并且除了在远侧端部处键合到腔插入器的键合焊盘的地方和在近侧端部处键合到附加电路的地方之外,导体209覆盖有绝缘材料。In one embodiment, flexible substrate 210 is formed from a flexible printed circuit material and is bonded except at the distal end where it is bonded to the bonding pads of the cavity interposer and at the proximal end where it is bonded to additional circuitry Outside of place, conductor 209 is covered with insulating material.

在可选实施例中,腔插入器300(图3)被形成为使得与LED 304相关联的键合焊盘302不在LED的正下方(如图1和图2中所示),而是与搁架306相邻并且在比搁架306更高的层级处,使得LED 304的上表面与键合焊盘302的上表面共面。对于此实施例,LED 304可以线键合到键合焊盘302,通过各向异性导电膜310耦接到键合焊盘302,或者通过薄柔性印刷电路耦接到键合焊盘302,而不是焊料球键合LED 304。在此实施例中,与LED相关联的馈通312比图1和图2的实施例的与LED相关联的馈通104更长。In an alternative embodiment, cavity interposer 300 (FIG. 3) is formed such that the bonding pads 302 associated with LED 304 are not directly beneath the LED (as shown in FIGS. 1 and 2), but are instead The shelf 306 is adjacent and at a higher level than the shelf 306 such that the upper surface of the LED 304 is coplanar with the upper surface of the bond pad 302 . For this embodiment, LED 304 may be wire bonded to bonding pad 302, coupled to bonding pad 302 through anisotropic conductive film 310, or coupled to bonding pad 302 through a thin flexible printed circuit, while Not a solder ball bonded LED 304. In this embodiment, the feedthrough 312 associated with the LED is longer than the feedthrough 104 associated with the LED of the embodiment of FIGS. 1 and 2 .

在圆形插入器400(图4)的实施例中,第一LED 402、任选的第二LED 404、任选的第三LED 406和任选的第四LED 408位于窗口205下方,这些LED位于相机立方体410的侧面。在正方形插入器500(图5)实施例中,第一LED 402、任选的第二LED 404、任选的第三LED 406和任选的第四LED 408也位于窗口205下方,这些LED位于相机立方体410的侧面。In the embodiment of circular interposer 400 (FIG. 4), first LED 402, optional second LED 404, optional third LED 406, and optional fourth LED 408 are located below window 205. These LEDs Located on the side of camera cube 410. In the square interposer 500 (FIG. 5) embodiment, first LED 402, optional second LED 404, optional third LED 406, and optional fourth LED 408 are also located below window 205, these LEDs are located Side of camera cube 410.

在可选实施例中,可以存在多于一个LED,在一些实施例中,提供至少一个白光LED用于白光彩色成像,并且提供单独的荧光成像LED,并且该荧光成像LED适于提供荧光刺激波长,荧光成像LED可以具有滤光器,以阻断穿过颜色滤光器阵列214的荧光成像拼接片(fluorescent-imaging tile)的波长的光。在具有荧光刺激或激发波长LED的实施例中,可以存在结合到颜色滤光器阵列214的拼接图案中的阻断荧光刺激波长的滤光器,其被配置成使感兴趣的荧光团的荧光发射波长的光通过,并且颜色滤光器阵列214可以拼接有颜色滤光器拼接图案,其包括比三个滤光器,即传统贝尔图案滤光器的红色、绿色和蓝色滤光器更多的滤光器。在特定实施例中,除了每个拼接图案中的红色、绿色和蓝色滤光器之外,还存在具有近红外中的通带的颜色滤光器,以及具有与一个或多个荧光团中的每一个相关联的通带的一个或多个颜色滤光器。例如,图5的实施例可以组装有布置在相机立方体410的相对侧上的两个白光LED 402、404,以及两个荧光刺激波长LED 406、408。在可选实施例中,可以存在几种不同波长的荧光刺激波长LED,以允许检测组织中的多种荧光团和在多种荧光团之间进行区分。In alternative embodiments more than one LED may be present, in some embodiments at least one white light LED is provided for white light color imaging and a separate fluorescence imaging LED is provided and adapted to provide the fluorescence stimulation wavelength The fluorescent imaging LED may have a filter to block light at wavelengths that pass through the fluorescent-imaging tile of the color filter array 214 . In embodiments with fluorescent stimulation or excitation wavelength LEDs, there may be filters that block the fluorescence stimulation wavelength incorporated into the tiling pattern of the color filter array 214 and configured to reduce the fluorescence of the fluorophore of interest. Light of the emission wavelength passes, and the color filter array 214 may be spliced with a color filter splicing pattern that includes more than three filters, namely red, green, and blue filters of a traditional Bell pattern filter. Lots of filters. In certain embodiments, in addition to the red, green, and blue filters in each tiled pattern, there are color filters with passbands in the near-infrared, and color filters with one or more fluorophores in Each associated passband is one or more color filters. For example, the embodiment of Figure 5 may be assembled with two white light LEDs 402, 404 arranged on opposite sides of the camera cube 410, and two fluorescence stimulation wavelength LEDs 406, 408. In alternative embodiments, several different wavelengths of fluorescence stimulation wavelength LEDs may be present to allow detection of and discrimination between multiple fluorophores in tissue.

内窥镜光学头部组件200用作内窥镜或需要在精细部位中成像的其他装置(诸如用于对发动机的缸孔或枪管内部执行光学检查的管道镜)的部件。使用光学头部组件的内窥镜的医疗用途包括结肠镜、子宫镜、腹腔镜、乙状结肠镜以及喉镜。在特定实施例中,包括插入器的整个内窥镜光学头部800、900或600具有小于1.5毫米的外径,并且特别适于在小直径内窥镜,诸如支气管镜、尿道镜和膀胱镜中的用途。The endoscopic optical head assembly 200 is used as a component of an endoscope or other device that requires imaging in delicate locations, such as a borescope used to perform optical inspections of the cylinder bore of an engine or the interior of a gun barrel. Medical uses for endoscopes using optical head assemblies include colonoscopy, hysteroscopy, laparoscopy, sigmoidoscopy, and laryngoscopy. In certain embodiments, the entire endoscope optical head 800, 900, or 600 including the inserter has an outer diameter of less than 1.5 mm and is particularly suitable for use in small diameter endoscopes such as bronchoscopes, urethroscopes, and cystoscopes. uses in.

在典型的内窥镜应用中,内窥镜端部600(图6)包括内窥镜主体602的端部、腔插入器400、用于一个或多个操纵线(未示出)的附接点以及穿过内窥镜主体602的管腔604的开口,诸如但不限于电烙器、线环和细胞采样器的操作工具可通过该开口到达内窥镜光学头部600、800或900前方的视场。内窥镜端部600形成内窥镜700的端部,内窥镜700具有内窥镜主体702、腔插入器400、500、802或902、操作手柄706(其可包括用于操纵线的控件)以及连接到电子数字图像显示&处理系统710的连接器708,该电子数字图像显示&处理系统710显示图像以指导医生或其他使用者。In a typical endoscopic application, endoscope end 600 (Fig. 6) includes the end of endoscope body 602, lumen inserter 400, attachment points for one or more steering wires (not shown) and an opening through the lumen 604 of the endoscope body 602 through which operating tools such as, but not limited to, electrocautery, wire loops, and cell samplers can reach the front of the endoscope optical head 600, 800, or 900. field of view. Endoscope end 600 forms the end of endoscope 700 having an endoscope body 702, a lumen inserter 400, 500, 802 or 902, an operating handle 706 (which may include controls for manipulating wires ) and a connector 708 to an electronic digital image display & processing system 710 that displays images to guide a physician or other user.

在实施例中,内窥镜光学头部通过制造腔插入器的晶片来形成,腔插入器单独成形,如参考图1或图3所描述的,但尚未切割成单独的腔插入器。然后,将单独的已切割的芯片型相机插入到腔插入器的每个腔中,并键合到每个腔的第一层级处的键合焊盘,并且LED也附接并键合到腔插入器的第三层级的键合焊盘。插入器的第一层级和第三层级的每个键合焊盘通过馈通耦接到第二层级处的腔插入器的键合焊盘。In an embodiment, the endoscope optical head is formed by fabricating a wafer of a lumen inserter that is individually formed as described with reference to Figure 1 or Figure 3, but has not been cut into individual lumen inserters. A separate diced chip-type camera is then inserted into each cavity of the cavity interposer and bonded to the bonding pads at the first level of each cavity, and the LEDs are also attached and bonded to the cavity The bonding pads on the third level of the interposer. Each bond pad of the first and third levels of the interposer is coupled by a feedthrough to a bond pad of the cavity interposer at the second level.

在没有边缘216的实施例中,间隔件晶片可以键合到腔插入器的晶片。然后将保护窗口的晶片键合在腔插入器的顶部上或间隔件晶片的顶部上。然后,典型地通过锯切来切割腔插入器,并且将电缆的导体附接到腔插入器的第二层级键合焊盘。In embodiments without edge 216, the spacer wafer may be bonded to the cavity inserter wafer. The protective window wafer is then bonded on top of the cavity inserter or on top of the spacer wafer. The cavity interposer is then cut, typically by sawing, and the conductors of the cable are attached to the second level bonding pads of the cavity interposer.

在一些实施例中,特别适合于在小直径内窥镜头800(图8)中使用,腔插入器802具有截断的等腰梯形形状。在这些实施例中,腔的短平行边804被配置成抵靠内窥镜头部800的弯曲内侧进行定位;短平行边804与相机立方体806相邻。长平行边808被配置成更靠近内窥镜头部800的中心进行定位,并且邻近相机立方体806和两个LED 810、812,一个LED定位于相机立方体806的各侧部上,并且与距短平行边804相比更靠近长平行边808。等腰边814、816以45度角从短平行边804向下朝向长平行边808延伸,但不与长平行边808会合,并在为LED 810、812提供空间后终止于竖直截断的侧边818、820。与如图5所图示的正方形插入器相比,使用截断等腰梯形形状的腔插入器可为内窥镜管腔825或内窥镜头部800的其他功能部分提供更多的空间。In some embodiments, particularly suitable for use in small diameter endoscopic lenses 800 (Fig. 8), the lumen inserter 802 has a truncated isosceles trapezoidal shape. In these embodiments, the short parallel side 804 of the cavity is configured to be positioned against the curved inside of the endoscope head portion 800; the short parallel side 804 is adjacent the camera cube 806. The long parallel side 808 is configured to be positioned closer to the center of the endoscopic lens portion 800 and adjacent the camera cube 806 and two LEDs 810, 812, one LED positioned on each side of the camera cube 806 and parallel to the short Side 804 is closer to long parallel side 808. Isosceles edges 814, 816 extend at a 45 degree angle from short parallel edge 804 downwardly toward long parallel edge 808, but do not meet long parallel edge 808, and terminate at vertically truncated sides after providing space for LEDs 810, 812. Side 818, 820. Using a lumen inserter with a truncated isosceles trapezoidal shape may provide more space for the endoscope lumen 825 or other functional portions of the endoscope head portion 800 than a square inserter as illustrated in FIG. 5 .

在内窥镜头部900的一些实施例中(图9),腔插入器902具有边缘904,盖子(未示出)可以密封到该边缘904,或者该边缘904可以填充有透明塑料材料,如前面参考边缘216所描述的。In some embodiments of the endoscope head 900 (Fig. 9), the lumen inserter 902 has an edge 904 to which a cover (not shown) may be sealed, or the edge 904 may be filled with a clear plastic material, as previously described Described with reference to edge 216.

组合combination

本文描述的腔插入器、相机立方体、LED和电缆可以以多种方式配置。发明人预期的配置有:The cavity inserter, camera cube, LEDs, and cables described in this article can be configured in a variety of ways. The configurations expected by the inventor are:

一种指定为A的腔插入器具有配置有腔的主体、适于耦接到芯片型相机立方体(CCube)的键合焊盘的多个第一键合焊盘,第一键合焊盘布置在所述腔的基部内、在第一层级处,第一键合焊盘通过馈通耦接到腔插入器的基部处、在第二层级处的第二键合焊盘;以及A cavity interposer, designated A, has a body configured with a cavity, a plurality of first bond pads adapted to be coupled to bond pads of a chip camera cube (CCube), a first bond pad arrangement a first bonding pad at a first level within the base of the cavity coupled to a second bonding pad at a second level at the base of the cavity interposer through a feedthrough; and

多个第三键合焊盘,多个第三键合焊盘适于耦接到发光二极管(LED)的键合焊盘,第三键合焊盘布置在第三层级处。第三键合焊盘通过馈通耦接到腔插入器的基部处在第二层级处的第四键合焊盘;并且第二键合焊盘和第四键合焊盘适于耦接到电缆的导体,其中第一层级、第二层级、和第三层级不同。A plurality of third bonding pads adapted to be coupled to bonding pads of light emitting diodes (LEDs), the third bonding pads being arranged at a third level. The third bonding pad is coupled to the fourth bonding pad at the second level at the base of the cavity interposer through the feedthrough; and the second bonding pad and the fourth bonding pad are adapted to be coupled to The conductors of a cable in which the first, second, and third levels are different.

一种指定为AA的内窥镜光学头部包括指定为A的腔插入器、至少一个LED和芯片型相机立方体,其中芯片型相机立方体电键合到第一键合焊盘;LED键合到第三键合焊盘;并且芯片型相机立方体的顶部和LED的顶部在同一层级处。An endoscopic optical head, designated AA, includes a cavity inserter designated A, at least one LED, and a chip camera cube, wherein the chip camera cube is electrically bonded to a first bonding pad; the LED is bonded to a Three bonding pads; and the top of the chip camera cube and the top of the LED are at the same level.

一种指定为AB的内窥镜光学头部包括指定为AA的内窥镜光学头部,并且具有电缆,电缆包括多个电导体,多个电导体键合到第二键合焊盘或第四键合焊盘的键合焊盘。An endoscopic optical head designated AB includes an endoscopic optical head designated AA and has a cable including a plurality of electrical conductors bonded to a second bond pad or a first Four bond pads for bonding pads.

一种指定为AC的内窥镜光学头部包括指定为AA或AB的内窥镜光学头部,并且具有球键合到第三键合焊盘的LED。An endoscopic optical head designated AC includes an endoscopic optical head designated AA or AB and having an LED ball bonded to a third bonding pad.

一种指定为AD的内窥镜光学头部包括指定为AA或AB的内窥镜光学头部,并具有线键合到第三键合焊盘的LED,并且其中第三键合焊盘与LED的顶部在同一层级处。An endoscopic optical head designated AD includes an endoscopic optical head designated AA or AB and having an LED wire bonded to a third bonding pad, and wherein the third bonding pad is The top of the LED is at the same level.

一种指定为AE的内窥镜光学头部包括指定为AA、AB、AC或AD的内窥镜光学头部,其中相机立方体具有拼接图案,其包括红外光学滤光器。An endoscopic optical head designated AE includes an endoscopic optical head designated AA, AB, AC, or AD, wherein the camera cube has a mosaic pattern that includes an infrared optical filter.

一种指定为AF的内窥镜光学头部包括指定为AA、AB、AC、AD或AE的内窥镜光学头部,其中存在多个LED,并且至少一个LED为白光LED,并且至少一个LED为荧光刺激波长LED。An endoscopic optical head designated AF includes an endoscopic optical head designated AA, AB, AC, AD, or AE, wherein a plurality of LEDs are present, and at least one LED is a white light LED, and at least one LED For the fluorescence stimulation wavelength LED.

一种指定为B的腔插入器,包括指定为A的腔插入器,在俯视平面图中为截断等腰梯形形状。A lumen inserter designated B, including a lumen inserter designated A, is in the shape of a truncated isosceles trapezoid in top plan view.

一种指定为BA的内窥镜头部,包括指定为B的腔插入器、第一白光LED、第二荧光刺激波长LED和芯片型相机立方体,芯片型相机立方体球键合至第一键合焊盘。An endoscope head section designated BA, including a cavity inserter designated B, a first white light LED, a second fluorescence stimulation wavelength LED, and a chip camera cube ball bonded to the first bond bond plate.

一种指定为BB的内窥镜头部,包括指定为B的腔插入器、至少两个LED和芯片型相机立方体,其中:芯片型相机立方体球键合至第一键合焊盘;两个LED键合至第三键合焊盘,两个LED在芯片型相机立方体的相对侧上,并且与距腔插入器的平行短边相比,更靠近腔插入器的平行长边;并且芯片型相机立方体的顶部和LED的顶部在同一层级处。An endoscope head portion designated BB, including a cavity inserter designated B, at least two LEDs, and a camera-on-a-chip cube, wherein: the camera-on-a-chip cube is ball bonded to a first bonding pad; and the two LEDs bonded to the third bond pad, the two LEDs on opposite sides of the camera-on-a-chip cube and closer to the parallel long sides of the cavity interposer than to the parallel short sides of the cavity interposer; and the camera-on-a-chip The top of the cube and the top of the LED are at the same level.

一种指定为BC的内窥镜头部,包括指定为B、BA或BB的腔插入器,其中腔插入器还包括边缘,并且还包括对相机立方体的保护,该保护选自由密封到边缘的透明盖和由腔插入器的边缘形成的空间中的透明塑料材料组成的组。An endoscope head portion designated BC, including a lumen inserter designated B, BA, or BB, wherein the lumen inserter further includes an edge, and further includes protection for the camera cube selected from a transparent seal sealed to the edge A set consisting of a cover and a transparent plastic material in the space formed by the edge of the cavity inserter.

一种指定为BD的内窥镜头部,包括指定为B的腔插入器,其中腔插入器的截断等腰梯形形状包括腔插入器的两个等腰边,每个等腰边从腔插入器的短平行边以45度角延伸,并终止于腔插入器的短竖直边,短竖直边延伸至腔插入器的长平行边。An endoscope head section designated BD, including a lumen inserter designated B, wherein the truncated isosceles trapezoidal shape of the lumen inserter includes two isosceles sides of the lumen inserter, each isosceles side extending from the lumen inserter The short parallel side extends at a 45 degree angle and terminates in the short vertical side of the cavity inserter, which extends to the long parallel side of the cavity inserter.

一种指定为C的内窥镜成像系统包括内窥镜,内窥镜包括腔插入器,腔插入器具有配置有腔的主体,主体包括多个第一键合焊盘,多个第一键合焊盘适于耦接至芯片型相机立方体(CCube)的键合焊盘,第一键合焊盘布置在腔的基部内、在第一层级处,第一键合焊盘通过馈通耦接至腔插入器的基部内、在第二层级处的第二焊盘;以及多个第三键合焊盘,多个第三键合焊盘适于耦接至发光二极管(LED)的键合焊盘,第三键合焊盘布置在第三层级处;第三键合焊盘通过馈通耦接至腔插入器的所述基部处、在第三层级处的第四键合焊盘;第二键合焊盘和第四键合焊盘适于耦接到电缆的导体;并且第一层级、第二层级和第三层级是不同的;芯片型相机立方体,芯片型相机立方体布置在腔内,并且具有电耦接到腔插入器的键合焊盘;发光二极管,发光二极管安装到第三键合焊盘;电缆,电缆具有耦接到第二键合焊盘和第四键合焊盘的第一端部和耦接到连接器的第二端部;并且连接器电连接到数字图像显示和处理系统。An endoscopic imaging system, designated C, includes an endoscope including a lumen inserter having a body configured with a lumen, the body including a plurality of first bonding pads, a plurality of first keys The bonding pads are adapted to be coupled to bonding pads of a chip camera cube (CCube), a first bonding pad being arranged within the base of the cavity at a first level, the first bonding pad being coupled via a feedthrough connected to a second pad at a second level within the base of the cavity interposer; and a plurality of third bonding pads adapted to couple to keys of a light emitting diode (LED) a bonding pad, a third bonding pad arranged at the third level; the third bonding pad is coupled to the fourth bonding pad at the third level at the base of the cavity interposer through a feedthrough ; the second bonding pad and the fourth bonding pad are adapted to be coupled to the conductor of the cable; and the first level, the second level and the third level are different; the chip-type camera cube is arranged on within the cavity and having a bonding pad electrically coupled to the cavity interposer; a light emitting diode mounted to a third bonding pad; and a cable having a second bonding pad coupled to the fourth bonding pad A first end of the pad is coupled to a second end of the connector; and the connector is electrically connected to the digital image display and processing system.

一种指定为CA的系统,包括指定为C的系统,其中内窥镜还包括耦接至腔插入器的键合焊盘的第二LED,第二LED适于提供荧光刺激波长的光,并且芯片型相机立方体具有颜色滤光器阵列,颜色滤光阵列以图案拼接,其包括被配置成阻断荧光刺激波长的光同时使荧光发射波长的光通过的滤光器。A system designated CA, including a system designated C, wherein the endoscope further includes a second LED coupled to a bonding pad of the cavity inserter, the second LED adapted to provide light at a fluorescence stimulation wavelength, and The chip camera cube has a color filter array mosaicd in a pattern that includes filters configured to block light at fluorescence stimulation wavelengths while passing light at fluorescence emission wavelengths.

可对上述方法和系统进行变更,而不背离其范围。因此,应当注意,包含在以上描述中或者在附图中示出的内容应当被解释为说明性的,而不是限制性的。下面的权利要求旨在覆盖本文描述的所有一般和特定特征,以及本方法和系统的范围的所有陈述,从语言的角度来说,可以说这些陈述落入它们之间。还可以预期的是,方法的步骤可以以不同于所图示的顺序执行,并且仍然在所附权利要求的含义内。Changes may be made to the methods and systems described above without departing from their scope. Therefore, it should be noted that what is contained in the above description or shown in the accompanying drawings is to be interpreted as illustrative rather than restrictive. The following claims are intended to cover all general and specific features described herein, and all statements of the scope of the present method and system which, from a linguistic perspective, may be said to fall between them. It is also contemplated that the steps of the methods may be performed in a different order than illustrated and still be within the meaning of the appended claims.

Claims (16)

1. A lumen inserter having a body configured with a lumen, the body comprising:
a plurality of first bond pads adapted to be coupled to bond pads of a chip camera cube (CCube), the first bond pads being disposed within a base of the cavity at a first level, the first bond pads being coupled to second bond pads at a second level at a base of the cavity interposer through a feedthrough; and
a plurality of third bond pads adapted to be coupled to bond pads of a Light Emitting Diode (LED), the third bond pads arranged at a third level;
the third bond pad is coupled to a fourth bond pad at the second level at the base of the cavity interposer through a feedthrough;
the second bond pad and the fourth bond pad are adapted to be coupled to a conductor of a cable; and
the first level, the second level, and the third level are different.
2. An endoscope optical head comprising the cavity inserter of claim 1, at least one LED, and a chip camera cube, wherein:
the chip camera cube is ball bonded to the first bond pad;
the LED is bonded to the third bond pad; and
the top of the chip camera cube and the top of the LED are at the same level.
3. The endoscope optical head of claim 2, further comprising:
a cable comprising a plurality of electrical conductors bonded to the bond pads of the second bond pad or the fourth bond pad.
4. An endoscope optical head as in claim 3 wherein the LED is ball bonded to the third bond pad.
5. The endoscope optical head of claim 3, wherein the LED is wire bonded to the third bond pad, and wherein the third bond pad is at the same level as the top of the LED.
6. The endoscope optical head of claim 5 wherein the chip camera cube has a stitching pattern comprising an infrared optical filter.
7. The endoscope optical head of claim 6 wherein there are a plurality of LEDs and at least one LED is a white light LED and at least one LED is a fluorescence stimulus wavelength LED.
8. The endoscope optical head of claim 4 wherein the camera cube has a stitching pattern comprising an infrared optical filter.
9. The endoscope optical head of claim 8 wherein there are a plurality of LEDs and at least one LED is a white light LED and at least one LED is a fluorescence stimulus wavelength LED.
10. The cavity inserter according to claim 1, having a truncated isosceles trapezoid shape in top plan view.
11. An endoscope head comprising the cavity interposer of claim 10, a first white LED, a second fluorescence stimulus wavelength LED, and a chip-type camera cube ball bonded to the first bond pad.
12. An endoscope optical head comprising the cavity inserter of claim 10, at least two LEDs, and a chip camera cube, wherein:
the chip camera cube is ball bonded to the first bond pad;
the two LEDs are bonded to the third bond pad, the two LEDs being on opposite sides of the chip camera cube and closer to a long parallel side of the cavity interposer than to a short parallel side of the cavity interposer; and
the top of the chip camera cube and the top of the LED are at the same level.
13. The endoscope optical head of claim 12 wherein the lumen inserter further comprises a rim and further comprising protection for the camera cube, the protection selected from the group consisting of a transparent cover sealed to the rim and a transparent plastic material in a space formed by the rim of the lumen inserter.
14. The endoscope optical head of claim 13 wherein the truncated isosceles trapezoid shape of the lumen inserter comprises two isosceles sides of the lumen inserter, each isosceles side extending at a 45 degree angle from the short parallel side of the lumen inserter and terminating in a short vertical side of the lumen inserter that extends to the long parallel side of the lumen inserter.
15. An endoscopic imaging system comprising an endoscope, the endoscope comprising:
a chip-type camera cube;
a cavity interposer having a body configured with a cavity, the body including a plurality of first bond pads coupled to bond pads of a chip camera cube (CCube), the first bond pads disposed within a base of the cavity at a first level, the first bond pads coupled to second bond pads at a second level at the base of the cavity interposer through feedthroughs; and
a plurality of third bond pads adapted to be coupled to bond pads of a Light Emitting Diode (LED), the third bond pads arranged at a third level; the third bond pad is coupled to a fourth bond pad at the second level at the base of the cavity interposer through a feedthrough; the second bond pad and the fourth bond pad are coupled to conductors of a cable; and the first level, the second level, the third level are different;
a light emitting diode mounted to the third bond pad;
the cable having a second end coupled to a connector; and
the connector is electrically connected to the digital image display and processing system.
16. The system of claim 15, wherein the endoscope further comprises a second LED coupled to a bond pad of the cavity interposer, the second LED adapted to provide light of a fluorescence stimulus wavelength, and the chip-type camera cube has a color filter array stitched in a pattern, the color filter array comprising a filter configured to block light of the fluorescence stimulus wavelength while passing light of a fluorescence emission wavelength.
CN202310567858.5A 2022-05-18 2023-05-18 Endoscope tip assembly in small diameter endoscopes using a truncated trapezoidal cavity inserter to allow camera and LED to be coplanar Pending CN117084617A (en)

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US17/747,803 US12251081B2 (en) 2021-10-18 2022-05-18 Endoscope tip assembly using truncated trapezoid cavity interposer to allow coplanar camera and LEDs in small-diameter endoscopes

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