CN117074666A - Test strip negative-positive identification method and device, electronic equipment and storage medium - Google Patents

Test strip negative-positive identification method and device, electronic equipment and storage medium Download PDF

Info

Publication number
CN117074666A
CN117074666A CN202311049839.XA CN202311049839A CN117074666A CN 117074666 A CN117074666 A CN 117074666A CN 202311049839 A CN202311049839 A CN 202311049839A CN 117074666 A CN117074666 A CN 117074666A
Authority
CN
China
Prior art keywords
color difference
test
test strip
light reflection
negative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202311049839.XA
Other languages
Chinese (zh)
Inventor
张俊
孙海军
周长明
原博
马骁勇
夏丽
唐雪茹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Xuanhang Technology Co ltd
Original Assignee
Hangzhou Xuanhang Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hangzhou Xuanhang Technology Co ltd filed Critical Hangzhou Xuanhang Technology Co ltd
Priority to CN202311049839.XA priority Critical patent/CN117074666A/en
Publication of CN117074666A publication Critical patent/CN117074666A/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G01N33/559Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody through a gel, e.g. Ouchterlony technique

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Spectrometry And Color Measurement (AREA)

Abstract

The disclosure provides a test strip negative-positive identification method, a device, electronic equipment and a storage medium, wherein the method comprises the following steps: acquiring the dark green light reflection values respectively corresponding to three test bits on the test strip to be identified, wherein the three test bits are used for respectively indicating the test positions of the C line, the T line and the middle area of the T line; and performing color difference operation based on the cyan light reflection values respectively corresponding to the three test positions, and determining the negative and positive of the test strip to be identified. According to the method, the light signal detection is carried out at three test positions, the color difference between the middle area and the T line can be determined through the color development combination, so that more accurate yin-yang identification is realized, in addition, yin-yang identification is carried out based on the cyan light reflection value, and the accuracy of the yin-yang identification is further improved.

Description

Test strip negative-positive identification method and device, electronic equipment and storage medium
Technical Field
The disclosure relates to the technical field of intelligent recognition, in particular to a test strip negative-positive recognition method, a test strip negative-positive recognition device, electronic equipment and a storage medium.
Background
When the test strip for detecting the colloidal gold antigen based on blood is used, a hemolysis phenomenon caused by the rupture of red blood cells in the blood can occur with a certain probability, and the hemolysis phenomenon can cause the bottom plate of the reaction area of the colloidal gold test strip to appear dark red or light red. The colloidal gold wire (C, T wire) for marking the result can be dark red or purple red under the condition of illumination, and is similar to the red of the bottom plate caused by hemolysis, so that certain interference can be caused to the identification of the CT wire after the hemolysis phenomenon occurs, and misjudgment of the result is caused.
The existing test strip generally adopts two groups of photoelectric sensing structures which emit light and receive light (namely, one group of red light or infrared light emitting tubes emit light and one group of photoelectric triodes receive light). The structure detects the C line (quality control line) and the T line (test line) of the colloidal gold test paper, and then judges the negative and positive of the test paper sample through the dominant representation of the CT line.
However, the traditional photoelectric transmission structure cannot accurately distinguish the red color caused by hemolysis or other reactions from the colloidal golden red color, other red colors are mistakenly identified as the colloidal golden red color, and the result is positive through a system judgment rule, so that the false positive false result is finally formed.
Disclosure of Invention
The embodiment of the disclosure at least provides a test strip negative-positive identification method, a test strip negative-positive identification device, an electronic device and a storage medium, so as to solve the problem of high false identification rate caused by similar spectrums of other red and colloidal gold red, and remarkably improve identification accuracy.
In a first aspect, an embodiment of the present disclosure provides a method for identifying negative and positive test strips, including:
obtaining the corresponding turquoise light reflection values of three test bits on the test strip to be identified, wherein the three test bits are used for respectively indicating the test positions of a C line, a T line and an intermediate area thereof;
And performing color difference operation based on the cyan light reflection values respectively corresponding to the three test positions, and determining the negative and positive of the test strip to be identified.
In one possible implementation manner, in a case that each test bit corresponds to a cyan light reflection value at a plurality of moments, the performing a color difference operation based on the cyan light reflection values respectively corresponding to the three test bits includes:
determining first turquoise light reflection values of a plurality of moments corresponding to a first test bit of the middle area and second turquoise light reflection values of a plurality of moments corresponding to a second test bit of the T line;
and performing color difference operation based on the first cyan light reflection values and the second cyan light reflection values to determine the negative and positive of the test strip to be identified.
In one possible implementation manner, in a case where the plurality of first cyan-green light reflection values and the plurality of second cyan-green light reflection values are collected in a preset effective sampling period, performing a color difference operation based on the plurality of first cyan-green light reflection values and the plurality of second cyan-green light reflection values includes:
performing color difference operation on the first and second turquoise light reflection values correspondingly acquired by the sampling points aiming at each sampling point in the preset effective sampling period to obtain a color difference operation value;
Determining the color difference change rate corresponding to each sampling point based on the color difference operation value obtained by each sampling point;
and determining the negative and positive of the test strip to be identified based on the color difference change rate corresponding to each sampling point.
In one possible embodiment, the method further comprises:
screening out sampling points with the color difference change rate larger than a first preset threshold value;
and determining the negative and positive of the test strip to be identified based on the color difference change rate corresponding to each screened sampling point.
In a possible implementation manner, the determining the yin-yang of the test strip to be identified based on the color difference change rates corresponding to the sampling points includes:
performing accumulation operation based on the color difference change rates corresponding to the sampling points respectively to obtain a color difference change rate sum value;
and determining the negative and positive of the test strip to be identified based on the color difference change rate and the value.
In a possible implementation manner, the preset effective sampling period includes a first sampling period used for indicating a period between a first moment and a second moment after reaction; and a second sampling period for indicating a period between the third time and the fourth time after the reaction;
The determining the yin-yang property of the test strip to be identified based on the color difference change rate and the value comprises the following steps:
summing the first color difference change rate sum value obtained by accumulation in the first sampling period and the second color difference change rate sum value obtained by accumulation in the second sampling period to obtain a color difference change rate total value;
under the condition that the total value of the color difference change rate is larger than 0, determining that the test strip to be identified is positive; and under the condition that the color difference change rate sum value is less than or equal to 0, determining that the test strip to be identified is negative.
In one possible implementation manner, the performing a color difference operation based on the plurality of first cyan light reflection values and the plurality of second cyan light reflection values includes:
verifying whether the reflection coefficient corresponding to the preset sampling moment meets a threshold judgment condition or not; the reflection coefficient is determined by the ratio of the dark green light reflection value corresponding to the test bit at the preset sampling time to the dark green light reflection value corresponding to the test bit at the initial power-on time;
and under the condition that the reflection coefficient is verified to be in accordance with the threshold judgment condition, performing color difference operation based on the reflected light value of the bluish green light acquired in the preset effective sampling period, wherein the sampling time of each sampling point in the preset effective sampling period is larger than the preset sampling time.
In one possible implementation manner, the verifying whether the reflection coefficient corresponding to the preset sampling time meets the threshold judgment condition includes:
under the condition that the preset sampling time indicates the initial time for starting reaction, verifying whether the reflection coefficient corresponding to the initial time is smaller than a second preset threshold value;
and under the condition that the preset sampling time indicates the effective time of the reaction, verifying whether the reflection coefficient corresponding to the effective time is larger than a third preset threshold value.
In a possible implementation manner, the obtaining the cyan light reflection values corresponding to the three test bits on the test strip to be identified includes:
the testing positions of the C line, the T line and the middle area thereof are respectively provided with a signal transmitting end, and the signal transmitting ends are used for transmitting cyan light signals to the corresponding testing positions;
and receiving the transmitted cyan-green light signals by using three signal receiving pipes which are respectively matched with the three signal transmitting ends, so as to obtain the cyan-green light reflection values respectively corresponding to the three test bits.
In a second aspect, the present disclosure further provides a test strip negative-positive identification device, including:
the acquisition module is used for acquiring the bluish green light reflection values respectively corresponding to three test bits on the test strip to be identified, wherein the three test bits are used for respectively indicating the test positions of the C line, the T line and the middle area of the T line;
And the identification module is used for carrying out color difference operation based on the cyan light reflection values respectively corresponding to the three test bits and determining the negative and positive of the test strip to be identified.
In a third aspect, the present disclosure further provides a test strip negative-positive identification device, including: a transceiver component and a processing module; the receiving and transmitting assembly is electrically connected with the processing module;
the receiving and transmitting assembly is used for collecting the bluish green light reflection values respectively corresponding to three test bits on the test strip to be identified, and the three test bits are used for respectively indicating the test positions of the C line, the T line and the middle area of the C line;
and the processing module is used for carrying out color difference operation based on the cyan light reflection values respectively corresponding to the three test bits and determining the negative and positive of the test strip to be identified.
In one possible implementation manner, the transceiver component comprises three signal transmitting ends and three signal receiving pipes, and the three signal transmitting ends and the three signal receiving pipes are arranged in a pairing manner;
the three signal transmitting ends are used for transmitting cyan-green light signals to the three test bits respectively;
the three signal receiving pipes are used for receiving the cyan light signals emitted by the signal emitting ends which are arranged in a matched mode, and the cyan light reflection values corresponding to the three test bits respectively are obtained.
In a fourth aspect, the present disclosure also provides an electronic device, including: a processor, a memory and a bus, the memory storing machine-readable instructions executable by the processor, the processor and the memory in communication over the bus when the electronic device is running, the machine-readable instructions when executed by the processor performing the test strip negative-positive identification method of the first aspect and any of its various embodiments.
In a fifth aspect, the present disclosure also provides a computer-readable storage medium having stored thereon a computer program which, when executed by a processor, performs the test strip negative-positive identification method as in the first aspect and any of its various embodiments.
By adopting the test strip negative-positive identification method, the device, the electronic equipment and the storage medium, under the condition that the cyan light reflection values respectively corresponding to the three test bits on the test strip to be identified are acquired, the negative-positive of the test strip to be identified can be determined based on the cyan light reflection values respectively corresponding to the three test bits. According to the method, the light signal detection is carried out at three test positions, the color difference between the middle area and the T line can be determined through the color development combination, for example, when the color of the T line area is heavier than that of the middle area, the result is positive, and if the color of the T line area is similar to that of the middle area, the result is negative, so that more accurate yin-yang identification is realized.
Other advantages of the present disclosure will be explained in more detail in connection with the following description and accompanying drawings.
It is to be understood that the foregoing description is only an overview of the technical solutions of the present disclosure, so that the technical means of the present disclosure may be generally understood and implemented in accordance with the content of the specification. The following specific examples illustrate the present disclosure in order to make the above and other objects, features and advantages of the present disclosure more comprehensible.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present disclosure, the drawings that are required to be used in the embodiments will be briefly described below. The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the disclosure and together with the description, serve to explain the technical aspects of the disclosure. It is appreciated that the drawings illustrate only certain embodiments of the disclosure and are therefore not to be considered limiting of its scope, for the person of ordinary skill in the art may derive other relevant drawings from the drawings without the benefit of the inventive effort. Also, like reference numerals are used to designate like parts throughout the figures. In the drawings:
FIG. 1 shows a flow chart of a test strip negative-positive identification method provided by an embodiment of the present disclosure;
fig. 2 is a schematic structural diagram of a test strip negative-positive identification device according to an embodiment of the present disclosure;
FIG. 3 is a schematic block diagram of a test strip negative-positive identification device according to an embodiment of the present disclosure;
fig. 4 shows a schematic diagram of an electronic device provided by an embodiment of the disclosure.
Detailed Description
Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
In the description of the embodiments of the present disclosure, it should be understood that terms such as "comprises" or "comprising," are intended to indicate that the disclosed features, numbers, steps, acts, components, portions, or combinations thereof, are present in the specification, and do not preclude the presence or addition of one or more other features, numbers, steps, acts, components, portions, or combinations thereof.
Unless otherwise indicated, "/" means or, e.g., A/B may represent A or B; "and/or" herein is merely an association relationship describing an association object, and means that three relationships may exist, for example, a and/or B may mean: a exists alone, A and B exist together, and B exists alone.
The terms "first," "second," and the like are used merely for convenience of description to distinguish between the same or similar technical features, and are not to be construed as indicating or implying a relative importance or quantity of such technical features. Thus, a feature defined by "first," "second," etc. may explicitly or implicitly include one or more such feature. In describing embodiments of the present disclosure, the term "plurality" means two or more unless otherwise indicated.
According to the research, the traditional photoelectric transmission structure cannot accurately distinguish the red caused by hemolysis or other reactions from the colloidal golden red, other red is mistakenly identified as the colloidal golden red, and the result is positive through a system judgment rule, so that the false positive false result is finally formed.
In order to at least partially solve one or more of the above problems and other potential problems, the present disclosure provides at least one test strip negative-positive identification scheme to solve the problem of high false identification rate caused by the close spectrum of other red colors to the colloidal gold red color, thereby significantly improving identification accuracy.
For the convenience of understanding the present embodiment, first, a detailed description will be given of a test strip negative-positive identification method disclosed in the embodiments of the present disclosure, where an execution body of the test strip negative-positive identification method provided in the embodiments of the present disclosure is generally an electronic device with a certain computing capability, and the electronic device includes, for example: the terminal device or server or other processing device may be a User Equipment (UE), mobile device, cellular phone, cordless phone, personal digital assistant (Personal Digital Assistant, PDA), or the like. In some possible implementations, the test strip negative-positive identification method may be implemented by a processor invoking computer readable instructions stored in a memory.
Referring to fig. 1, a flowchart of a test strip negative-positive identification method provided by an embodiment of the present disclosure is shown, and the method includes the following steps S101 to S102:
s101: acquiring the dark green light reflection values respectively corresponding to three test bits on the test strip to be identified, wherein the three test bits are used for respectively indicating the test positions of the C line, the T line and the middle area of the T line;
s102: and performing color difference operation based on the cyan light reflection values respectively corresponding to the three test positions, and determining the negative and positive of the test strip to be identified.
In order to facilitate understanding of the test strip negative-positive identification method provided by the embodiment of the present disclosure, an application scenario of the method is first described in detail. The test strip negative-positive identification method in the embodiment of the disclosure can be mainly applied to the field of rapid detection of infectious diseases, for example, detection of AIDS virus (Human Immunodeficiency Virus, HIV), and can also be used in other detection fields, and is not particularly limited herein. Given the broad necessity of HIV detection, the following is exemplified by HIV detection.
When the detection is actually carried out, a sample to be detected (blood) can be added to a sample pad at one end of the test strip, then moves forward through capillary action, dissolves the colloidal gold labeled reagent on the binding pad, then reacts with each other, and moves to a fixed antigen or antibody area, and when the binding agent of the blood to be detected and the gold labeled reagent are specifically combined with each other to be trapped, the binding agent is gathered on the detection strip, and then a color development result can be observed through naked eyes, namely, the binding agent and the colloidal gold reagent are subjected to dominant display on a C, T line of the test strip through the electric adsorption characteristic of the antigen and the colloidal gold particle, so that the yin-yang result of the sample is judged.
Considering false positive and false recognition results possibly caused by adopting two groups of one-to-one photoelectric sensing structures in the related art, the embodiment of the disclosure adopts three groups of one-to-one test strip negative and positive recognition devices to carry out test strip negative and positive recognition, and as shown in fig. 2, the negative and positive recognition device mainly comprises a receiving and transmitting assembly 11 and a processing module 22; the transceiver component 11 is electrically connected with the processing module 22;
The receiving and transmitting assembly 11 is used for collecting the bluish green light reflection values respectively corresponding to three test bits on the test strip to be identified, wherein the three test bits are used for respectively indicating the test positions of the C line, the T line and the middle area of the T line;
and the processing module 22 is used for performing color difference operation based on the cyan light reflection values respectively corresponding to the three test bits to determine the negative and positive of the test strip to be identified.
The transceiver assembly 11 here includes three signal transmitting ends and three signal receiving tubes. As shown in fig. 2, three signal transmitting terminals (a c 、A b 、A t ) Three signal receiving pipes (B) c 、B b 、B t ) Pairing arrangement. The test paper strip to be identified reacts under the capillary action, and in the reaction process, A c 、A b 、A t The three test bit C lines, the middle area and the T lines on the test strip are respectively irradiated, and the specific range can be the positive and negative 0.5mm of the periphery of each test bit. Through B c 、B b 、B t And acquiring data of the transmitted signals to obtain reflection values corresponding to the three test bits respectively.
In order to further improve the accuracy of identification, the embodiment of the disclosure may use the cyan light with the main emission wavelength of 512nm to irradiate, which mainly considers that the cyan light has the excellent characteristics of stable irradiation signal, strong linearity, general activity and the like, and is not suitable for generating interference caused by red caused by hemolysis or other reactions, so that more accurate yin-yang identification can be performed through a color development combination.
The signal receiving tube here may employ a 0805-packaged photodiode, and perform signal reception in a voltage range of 3.3V, and the active wavelength range thereof is about 800 nm.
Based on the test strip negative-positive identification device, the test strip negative-positive identification method provided by the embodiment of the disclosure can obtain the cyan light reflection values of three test positions respectively collected by the three signal receiving pipes, and then, the negative-positive of the test strip to be identified is determined based on the cyan light reflection values respectively corresponding to the three test positions.
In the process of carrying out the test strip negative-positive identification, the color difference of the T line area and the middle area is mainly compared, for example, if the color of the T line area is heavier than that of the middle area, the test strip negative-positive identification is positive, and if the color of the T line area is similar to that of the middle area, the test strip negative-positive identification is judged to be negative. The color development combination performed by combining the middle region can perform more accurate judgment, and even under the condition that the blood trend is irregular, background color and other interferences exist, accurate yin-yang identification can be realized based on the color difference of the T line and the middle position.
In consideration of different influences of acquisition results at different moments on yin and yang identification, in the process of actually carrying out yin and yang identification, the embodiment of the disclosure can combine the cyan-green light reflection values at a plurality of moments corresponding to each test bit to carry out difference operation, so that more accurate yin and yang identification is realized. The method specifically comprises the following steps:
Step one, determining first turquoise light reflection values of a plurality of moments corresponding to a first test bit of an intermediate area and second turquoise light reflection values of a plurality of moments corresponding to a second test bit of a T line;
and secondly, performing color difference operation based on the first cyan light reflection values and the second cyan light reflection values, and determining the negative and positive of the test strip to be identified.
As the sample to be tested (blood) is applied to the sample pad at one end of the test strip, it is also necessary for a certain period of time for the development to actually occur due to capillary action moving forward. Here, in order to further improve the accuracy of the identification, the color difference operation may be performed based on the reflected light value of the green light collected in the preset effective sampling period, which may be specifically implemented by the following steps:
step one, performing color difference operation on a first cyan light reflection value and a second cyan light reflection value which are correspondingly acquired by sampling points aiming at each sampling point in a preset effective sampling period to obtain a color difference operation value;
step two, determining the color difference change rate corresponding to each sampling point based on the color difference operation value obtained by each sampling point;
and thirdly, determining the negative and positive of the test strip to be identified based on the color difference change rate corresponding to each sampling point.
Here, for each sampling point in the preset effective sampling period, the color difference operation value corresponding to the two test bits (namely the first test bit and the second test bit) can be determined, the color difference change rate of the corresponding sampling point can be obtained through the color difference derivation of the color difference operation value corresponding to each sampling point, and then the color difference change rate and the value for carrying out the yin-yang identification can be determined through the accumulation operation of the color difference change rate.
The preset effective sampling period may be a first sampling period and a second sampling period after the reaction, where the first sampling period may be, for example, a period of 5min to 8min, and the second sampling period may be, for example, a period of 12min to 15min, which mainly considers that the color development effect is optimal in the two sampling periods.
In practical application, the sum operation can be performed on the first color difference change rate sum value and the second color difference change rate sum value corresponding to the two sampling periods (i.e., the first sampling period and the second sampling period), so that yin and yang can be identified based on the sum result, and the method specifically comprises the following steps:
step one, summing the first color difference change rate sum value obtained by accumulation in a first sampling period and the second color difference change rate sum value obtained by accumulation in a second sampling period to obtain a color difference change rate total value;
Step two, under the condition that the total value of the color difference change rate is larger than 0, determining that the test strip to be identified is positive; and under the condition that the color difference change rate and the value are smaller than or equal to 0, determining that the test strip to be identified is negative.
Here, by summing the color difference change rates and values corresponding to the two sampling periods, the result of the identification of the yin and yang in the entire color development period can be determined.
The sampling period corresponds to a plurality of sampling points, whether for a first sampling period or a second sampling period. Taking a first sampling period as an example, 90 sampling points are corresponding in total in the period of 5min-8min, the color difference operation value between the first and second turquoise light reflection values corresponding to each sampling point respectively also changes along with the extension of sampling, and the color difference change rate of the sampling points can represent the color difference change condition between the first test bit in the middle area and the second test bit in the T line in the first sampling period; similarly, in the second sampling period of 5min-8min, the color difference change condition between the first test bit where the middle area is located and the second test bit where the T line is located can also be determined based on the color difference change rate, which is not described here again.
In practical application, for the color difference change condition between two test bits, if the color difference change rate corresponding to one sampling point is greater than a first preset threshold (for example, 1), it is indicated that the sampling data is invalid, and at this time, the corresponding sampling point can be screened out, so that the validity of the identification result is ensured.
Here, in order to further ensure the validity of the identification result, before the actual color difference operation is performed, it may be verified whether the reflection coefficient corresponding to the preset sampling time meets the threshold judgment condition, and in the case where it is verified that the reflection coefficient meets the threshold judgment condition, the color difference operation is performed based on the reflected value of the cyan light collected in the preset effective sampling period.
The reflection coefficient corresponding to the preset sampling time may be determined by a ratio between a cyan light reflection value corresponding to the test bit at the preset sampling time and a cyan light reflection value corresponding to the test bit at the initial power-on time, and specifically may be determined by ratios respectively corresponding to the three test bits together.
The preset sampling time may be, for example, an initial time of starting the reaction, and at this time, the subsequent color difference operation may be performed by verifying that the reflection coefficient corresponding to the initial time is smaller than a second preset threshold (e.g. 0.85); for example, the effective time of the effective reaction may be a valid time, and the subsequent color difference operation may be performed by verifying that the reflection coefficient corresponding to the valid time is greater than a third preset threshold (e.g., 0.75).
In order to facilitate further understanding of the method for identifying the negative and positive of the test strip provided in the embodiments of the present disclosure, the following may be further described with reference to a schematic structural diagram of the device for identifying the negative and positive of the test strip shown in fig. 2.
Here, three signal receiving pipes B are set c 、B b 、B t The value of the respectively received signal (i.e. the reflected value of the bluish green light) is X cn 、X bn 、X tn
1. Record X at initial power-up s =(X cs 、X bs 、X ts );
2. Recording the start time X of the reaction k =(X ck 、X bk 、X tk ) Calculating an initial reflection coefficient T k =X k /X s If T k <0.85 (corresponding to a second preset threshold value), mark X k The method comprises the steps of carrying out a first treatment on the surface of the The effective recording time is { X } k ,X k+450 };
3. When the sampling period is 2s, the effective sampling period is defined as 5min-8min (corresponding to the first sampling period) and 12min-15min (corresponding to the second sampling period). I.e. X m =(X cm 、X bm 、X tm ) Wherein m is E (151, 240), X n =(X cn 、X bn 、X tn ) Wherein n E (361, 450);
4. note X at the time of effective reaction 90 =(X c90 、X b90 、X t90 ) Calculate the effective reflection coefficient T 90 =X c90 /X cs If T 90 >0.75 (corresponding to a third preset threshold), the output is invalid; if T 90 If less than or equal to 0.75, thenEntering the next step;
5. calculating a color difference operation value U of each sampling point in a first sampling period m =X bm -X tm And the color difference operation value U of each sampling point in the second sampling period n =X bn -X tn
6. Calculating a region determination value (i.e., a color difference change rate) V m =dU m /dt,V n =dU n /dt;
7. If V is m >1 (corresponding to a first preset threshold), then it is determined that the sample value is invalid for the first sampling period, and similarly, if V n >1 (corresponding to a first preset threshold), determining that the sampling value in the second sampling period is invalid;
8. calculating the total value of the color difference change rateIf V is>And 0, judging that the test strip is positive, and judging that the test strip is negative if V is less than or equal to 0.
In summary, it is known that the test strip negative-positive identification method provided by the embodiment of the present disclosure distinguishes negative positive by comparing the difference of the color development changes of the T line region and the middle region. However, the calculated values themselves differ due to factors such as installation errors, structural errors, resistance errors, production errors of the lamp and the receiving tube, and the like. The color difference is led, so that the change rate of the color difference of the T line position and the middle area is obtained, the yin-yang expansion judgment is further carried out, the interference and the error caused by the used components can be accurately eliminated, and the recognition rate of the color development of the test paper strip can be improved better.
In addition, background color such as blood is used as interference color of test strip color development, the embodiment of the disclosure introduces color value of the middle area, and the difference of the chromatic difference on the test strip is represented by calculating the chromatic difference change rate of the T line and the middle area, so that influence caused by the interference color is eliminated, and recognition accuracy is further improved by combining with light irradiation of cyan.
In the description of the present specification, descriptions with reference to the terms "some possible embodiments," "some embodiments," "examples," "specific examples," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiments or examples is included in at least one embodiment or example of the present disclosure, and that the above terms do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, the various embodiments or examples described in this specification and the features of the various embodiments or examples may be combined and combined by those skilled in the art without contradiction.
With respect to the method flow diagrams of the disclosed embodiments, certain operations are described as distinct steps performed in a certain order. Such a flowchart is illustrative and not limiting. Some steps described herein may be grouped together and performed in a single operation, or may be divided into multiple sub-steps and may be performed in an order different than that shown herein. The various steps illustrated in the flowcharts may be implemented in any manner by any circuit structure and/or tangible mechanism (e.g., by software running on a computer device, hardware (e.g., processor or chip implemented logic functions), etc., and/or any combination thereof).
It will be appreciated by those skilled in the art that in the methods described in the above embodiments, the written order of steps does not imply a strict order of execution, and that the specific order of execution of the steps should be determined by its function and possible inherent logic.
Based on the same inventive concept, the embodiment of the disclosure further provides a test strip negative-positive identification device corresponding to the test strip negative-positive identification method, and since the principle of solving the problem of the device in the embodiment of the disclosure is similar to that of the test strip negative-positive identification method in the embodiment of the disclosure, the implementation of the device can refer to the implementation of the method, and the repetition is omitted.
Referring to fig. 3, a schematic diagram of a test strip negative-positive identification device according to an embodiment of the disclosure is shown, where the device includes: an acquisition module 301 and an identification module 302; wherein,
the acquiring module 301 is configured to acquire cyan light reflection values corresponding to three test bits on the test strip to be identified, where the three test bits are used to indicate test positions of a C line, a T line, and an intermediate region thereof, respectively;
the identification module 302 is configured to perform a color difference operation based on the cyan light reflection values corresponding to the three test bits, and determine the negative and positive of the test strip to be identified.
By adopting the test strip negative-positive identification device, under the condition that the cyan light reflection values respectively corresponding to the three test positions on the test strip to be identified are collected, the color difference operation can be carried out on the basis of the cyan light reflection values respectively corresponding to the three test positions so as to determine the negative positive of the test strip to be identified. According to the method, the light signal detection is carried out at three test positions, the color difference between the middle area and the T line can be determined through the color development combination, for example, when the color of the T line area is heavier than that of the middle area, the result is positive, and if the color of the T line area is similar to that of the middle area, the result is negative, so that more accurate yin-yang identification is realized.
In a possible implementation manner, in the case that each test bit corresponds to a cyan light reflection value at a plurality of moments, the identifying module 302 is specifically configured to perform a color difference operation based on the cyan light reflection values respectively corresponding to the three test bits according to the following steps:
determining first turquoise light reflection values of a plurality of moments corresponding to a first test bit of the middle area and second turquoise light reflection values of a plurality of moments corresponding to a second test bit of the T line;
And performing color difference operation based on the plurality of first cyan light reflection values and the plurality of second cyan light reflection values, and determining the negative and positive of the test strip to be identified.
In one possible implementation manner, in the case that the plurality of first cyan light reflection values and the plurality of second cyan light reflection values are the collected cyan light reflection values within the preset effective sampling period, the identifying module 302 is specifically configured to perform the color difference operation based on the plurality of first cyan light reflection values and the plurality of second cyan light reflection values according to the following steps:
performing color difference operation on the first and second turquoise light reflection values acquired by the sampling points correspondingly aiming at each sampling point in a preset effective sampling period to obtain a color difference operation value;
determining the color difference change rate corresponding to each sampling point based on the color difference operation value obtained by each sampling point;
and determining the negative and positive of the test strip to be identified based on the color difference change rates corresponding to the sampling points.
In one possible implementation, the identification module 302 is further configured to:
screening out sampling points with the color difference change rate larger than a first preset threshold value;
and determining the negative and positive of the test strip to be identified based on the color difference change rate corresponding to each screened sampling point.
In a possible implementation manner, the identification module 302 is specifically configured to determine the yin-yang of the test strip to be identified based on the respective color difference change rates of the respective sampling points according to the following steps:
performing accumulation operation based on the color difference change rates corresponding to the sampling points respectively to obtain a color difference change rate and a value;
and determining the negative and positive of the test strip to be identified based on the color difference change rate and the value.
In one possible implementation, the preset valid sampling period includes a first sampling period for indicating a time between a first time and a second time after the reaction; and a second sampling period for indicating a period between the third time and the fourth time after the reaction;
the identification module 302 is specifically configured to determine the yin-yang of the test strip to be identified based on the rate of change of color difference and the value according to the following steps:
summing the first color difference change rate sum value obtained by accumulation in the first sampling period and the second color difference change rate sum value obtained by accumulation in the second sampling period to obtain a color difference change rate total value;
under the condition that the total value of the color difference change rate is larger than 0, determining that the test strip to be identified is positive; and under the condition that the color difference change rate and the value are smaller than or equal to 0, determining that the test strip to be identified is negative.
In one possible implementation, the identification module 302 is specifically configured to perform a color difference operation based on the plurality of first green light reflection values and the plurality of second green light reflection values according to the following steps:
verifying whether the reflection coefficient corresponding to the preset sampling moment meets a threshold judgment condition or not; the reflection coefficient is determined by the ratio of a dark green light reflection value corresponding to the preset sampling time at the test bit to a dark green light reflection value corresponding to the initial power-on time at the test bit;
and under the condition that the reflection coefficient is verified to be in accordance with the threshold judgment condition, performing color difference operation based on the reflected value of the bluish green light acquired in the preset effective sampling period, wherein the sampling time of each sampling point in the preset effective sampling period is larger than the preset sampling time.
In a possible implementation manner, the identifying module 302 is specifically configured to verify whether the reflection coefficient corresponding to the preset sampling time meets the threshold judgment condition according to the following steps:
under the condition that the preset sampling time indicates the initial time for starting reaction, verifying whether the reflection coefficient corresponding to the initial time is smaller than a second preset threshold value;
and under the condition that the preset sampling time indicates the effective time of the reaction, verifying whether the reflection coefficient corresponding to the effective time is larger than a third preset threshold value.
In a possible implementation manner, the obtaining module 301 is specifically configured to obtain the cyan light reflection values corresponding to the three test bits on the test strip to be identified according to the following steps:
the test positions of the C line, the T line and the middle area thereof are respectively provided with a signal transmitting end, and the signal transmitting ends are used for transmitting cyan light signals to the corresponding test positions;
and receiving the transmitted cyan-green light signals by using three signal receiving pipes which are respectively matched with the three signal transmitting ends, so as to obtain the cyan-green light reflection values respectively corresponding to the three test bits.
It should be noted that, the apparatus in the embodiments of the present disclosure may implement each process of the foregoing embodiments of the method, and achieve the same effects and functions, which are not described herein again.
The embodiment of the disclosure further provides an electronic device, which may be, for example, the above-mentioned test strip negative-positive identification device, as shown in fig. 4, which is a schematic structural diagram of the electronic device provided in the embodiment of the disclosure, including: a processor 401, a memory 402, and a bus 403. The memory 402 stores machine-readable instructions executable by the processor 401 (e.g., execution instructions corresponding to the acquisition module 301, the identification module 302, etc. in the apparatus of fig. 3), and when the electronic device is running, the processor 401 and the memory 402 communicate through the bus 403, the machine-readable instructions execute by the processor 401:
Acquiring the dark green light reflection values respectively corresponding to three test bits on the test strip to be identified, wherein the three test bits are used for respectively indicating the test positions of the C line, the T line and the middle area of the T line;
and performing color difference operation based on the cyan light reflection values respectively corresponding to the three test positions, and determining the negative and positive of the test strip to be identified.
The disclosed embodiments also provide a computer readable storage medium having a computer program stored thereon, which when executed by a processor performs the steps of the test strip negative-positive identification method described in the above method embodiments. Wherein the storage medium may be a volatile or nonvolatile computer readable storage medium.
The embodiments of the present disclosure further provide a computer program product, where the computer program product carries a program code, where instructions included in the program code may be used to perform the steps of the test strip negative-positive identification method described in the above method embodiments, and specifically reference may be made to the above method embodiments, which are not described herein.
Wherein the above-mentioned computer program product may be realized in particular by means of hardware, software or a combination thereof. In an alternative embodiment, the computer program product is embodied as a computer storage medium, and in another alternative embodiment, the computer program product is embodied as a software product, such as a software development kit (Software Development Kit, SDK), or the like.
The various embodiments of the disclosure are described in an incremental manner, and the same or similar parts of the various embodiments are referred to each other, each of which is emphasized by the differences from the other embodiments. In particular, for apparatus, devices and computer readable storage medium embodiments, the description thereof is simplified as it is substantially similar to the method embodiments, as relevant points may be found in part in the description of the method embodiments.
The apparatus, the device, and the computer readable storage medium provided in the embodiments of the present disclosure are in one-to-one correspondence with the methods, and therefore, the apparatus, the device, and the computer readable storage medium also have similar advantageous technical effects as the corresponding methods, and since the advantageous technical effects of the methods have been described in detail above, the advantageous technical effects of the apparatus, the device, and the computer readable storage medium are not repeated herein.
Those skilled in the art will appreciate that the embodiments of the present disclosure can be implemented as a method and apparatus (device or system), or as a computer-readable storage medium. Accordingly, the present disclosure may take the form of an entirely hardware embodiment, an entirely software embodiment, or an embodiment combining software and hardware aspects. Furthermore, the present disclosure may take the form of a computer-readable storage medium embodied in one or more computer-usable storage media including, but not limited to, magnetic disk storage, compact disk read-only memory (CD-ROM), optical storage, and the like.
The present disclosure is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (devices or systems) and computer-readable storage media according to embodiments of the disclosure. It will be understood that each flow and/or block of the flowchart illustrations and/or block diagrams, and combinations of flows and/or blocks in the flowchart illustrations and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions specified in the flowchart and/or block diagram block or blocks.
These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including instruction means which implement the function specified in the flowchart and/or block diagram block or blocks.
These computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified in the flowchart and/or block diagram block or blocks.
In one typical configuration, a computing device includes one or more processors (CPUs), input/output interfaces, network interfaces, and memory.
The memory may include volatile memory, random Access Memory (RAM), and/or nonvolatile memory, such as Read Only Memory (ROM) or Flash memory (Flash RAM), among others, in a computer readable medium. Memory is an example of computer-readable media.
Computer-readable media include both permanent and non-permanent, removable and non-removable media, and information storage may be implemented by any method or technology. The information may be computer readable instructions, data structures, modules of a program, or other data. Examples of computer-readable storage media include, but are not limited to, phase-change memory (PRAM), static Random Access Memory (SRAM), dynamic Random Access Memory (DRAM), other types of random access memory, read only memory, electrically Erasable Programmable Read Only Memory (EEPROM), flash memory or other memory technology, CD-ROM, digital Versatile Disks (DVD) or other optical storage, magnetic cassettes, magnetic tape magnetic disk storage or other magnetic storage devices, or any other non-transmission medium, which can be used to store information that can be accessed by a computing device. Furthermore, although the operations of the methods of the present disclosure are depicted in the drawings in a particular order, this is not required to either imply that the operations must be performed in that particular order or that all of the illustrated operations be performed to achieve desirable results. In addition, some steps may be omitted, multiple steps may be combined into one step to be performed, and/or one step may be decomposed into multiple sub-steps to be performed.
While the spirit and principles of the present disclosure have been described above with reference to several embodiments, it should be understood that the disclosure is not limited to the particular embodiments disclosed nor does the division of aspects mean that features in these aspects cannot be combined. The disclosure is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the appended claims.

Claims (14)

1. A test strip negative-positive identification method, characterized by comprising the following steps:
obtaining the corresponding turquoise light reflection values of three test bits on the test strip to be identified, wherein the three test bits are used for respectively indicating the test positions of a C line, a T line and an intermediate area thereof;
and performing color difference operation based on the cyan light reflection values respectively corresponding to the three test positions, and determining the negative and positive of the test strip to be identified.
2. The method according to claim 1, wherein, in the case that each test bit corresponds to a cyan light reflection value at a plurality of moments, the performing a color difference operation based on the cyan light reflection values respectively corresponding to the three test bits includes:
determining first turquoise light reflection values of a plurality of moments corresponding to a first test bit of the middle area and second turquoise light reflection values of a plurality of moments corresponding to a second test bit of the T line;
And performing color difference operation based on the first cyan light reflection values and the second cyan light reflection values to determine the negative and positive of the test strip to be identified.
3. The method according to claim 2, wherein, in the case where the plurality of first and second cyan light reflection values are collected during a preset effective sampling period, performing a color difference operation based on the plurality of first and second cyan light reflection values includes:
performing color difference operation on the first and second turquoise light reflection values correspondingly acquired by the sampling points aiming at each sampling point in the preset effective sampling period to obtain a color difference operation value;
determining the color difference change rate corresponding to each sampling point based on the color difference operation value obtained by each sampling point;
and determining the negative and positive of the test strip to be identified based on the color difference change rate corresponding to each sampling point.
4. A method according to claim 3, characterized in that the method further comprises:
screening out sampling points with the color difference change rate larger than a first preset threshold value;
And determining the negative and positive of the test strip to be identified based on the color difference change rate corresponding to each screened sampling point.
5. The method according to claim 3 or 4, wherein determining the yin-yang of the test strip to be identified based on the respective color difference change rates corresponding to the sampling points includes:
performing accumulation operation based on the color difference change rates corresponding to the sampling points respectively to obtain a color difference change rate sum value;
and determining the negative and positive of the test strip to be identified based on the color difference change rate and the value.
6. The method of claim 5, wherein the predetermined effective sampling period comprises a first sampling period indicating a time between a first time and a second time after the reaction; and a second sampling period for indicating a period between the third time and the fourth time after the reaction;
the determining the yin-yang property of the test strip to be identified based on the color difference change rate and the value comprises the following steps:
summing the first color difference change rate sum value obtained by accumulation in the first sampling period and the second color difference change rate sum value obtained by accumulation in the second sampling period to obtain a color difference change rate total value;
Under the condition that the total value of the color difference change rate is larger than 0, determining that the test strip to be identified is positive; and under the condition that the color difference change rate sum value is less than or equal to 0, determining that the test strip to be identified is negative.
7. The method of claim 3 or 4, wherein performing a color difference operation based on the plurality of first cyan light reflection values and the plurality of second cyan light reflection values comprises:
verifying whether the reflection coefficient corresponding to the preset sampling moment meets a threshold judgment condition or not; the reflection coefficient is determined by the ratio of the dark green light reflection value corresponding to the test bit at the preset sampling time to the dark green light reflection value corresponding to the test bit at the initial power-on time;
and under the condition that the reflection coefficient is verified to be in accordance with the threshold judgment condition, performing color difference operation based on the reflected light value of the bluish green light acquired in the preset effective sampling period, wherein the sampling time of each sampling point in the preset effective sampling period is larger than the preset sampling time.
8. The method of claim 7, wherein verifying whether the reflection coefficient corresponding to the preset sampling time meets the threshold judgment condition comprises:
Under the condition that the preset sampling time indicates the initial time for starting reaction, verifying whether the reflection coefficient corresponding to the initial time is smaller than a second preset threshold value;
and under the condition that the preset sampling time indicates the effective time of the reaction, verifying whether the reflection coefficient corresponding to the effective time is larger than a third preset threshold value.
9. The method according to any one of claims 1 to 4, wherein the obtaining the cyan light reflection values corresponding to the three test bits on the test strip to be identified includes:
the testing positions of the C line, the T line and the middle area thereof are respectively provided with a signal transmitting end, and the signal transmitting ends are used for transmitting cyan light signals to the corresponding testing positions;
and receiving the transmitted cyan-green light signals by using three signal receiving pipes which are respectively matched with the three signal transmitting ends, so as to obtain the cyan-green light reflection values respectively corresponding to the three test bits.
10. A test strip negative-positive identification device, comprising:
the acquisition module is used for acquiring the bluish green light reflection values respectively corresponding to three test bits on the test strip to be identified, wherein the three test bits are used for respectively indicating the test positions of the C line, the T line and the middle area of the T line;
And the identification module is used for carrying out color difference operation based on the cyan light reflection values respectively corresponding to the three test bits and determining the negative and positive of the test strip to be identified.
11. A test strip negative-positive identification device, comprising: a transceiver component and a processing module; the receiving and transmitting assembly is electrically connected with the processing module;
the receiving and transmitting assembly is used for collecting the bluish green light reflection values respectively corresponding to three test bits on the test strip to be identified, and the three test bits are used for respectively indicating the test positions of the C line, the T line and the middle area of the C line;
and the processing module is used for carrying out color difference operation based on the cyan light reflection values respectively corresponding to the three test bits and determining the negative and positive of the test strip to be identified.
12. The device of claim 11, wherein the transceiver assembly comprises three signal transmitting ends and three signal receiving tubes, and the three signal transmitting ends and the three signal receiving tubes are paired;
the three signal transmitting ends are used for transmitting cyan-green light signals to the three test bits respectively;
the three signal receiving pipes are used for receiving the cyan light signals emitted by the signal emitting ends which are arranged in a matched mode, and the cyan light reflection values corresponding to the three test bits respectively are obtained.
13. An electronic device, comprising: a processor, a memory and a bus, the memory storing machine readable instructions executable by the processor, the processor and the memory in communication over the bus when the electronic device is running, the machine readable instructions when executed by the processor performing the test strip negative-positive identification method of any one of claims 1 to 9.
14. A computer-readable storage medium, characterized in that the computer-readable storage medium has stored thereon a computer program which, when executed by a processor, performs the test strip negative-positive identification method according to any one of claims 1 to 9.
CN202311049839.XA 2023-08-18 2023-08-18 Test strip negative-positive identification method and device, electronic equipment and storage medium Pending CN117074666A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311049839.XA CN117074666A (en) 2023-08-18 2023-08-18 Test strip negative-positive identification method and device, electronic equipment and storage medium

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202311049839.XA CN117074666A (en) 2023-08-18 2023-08-18 Test strip negative-positive identification method and device, electronic equipment and storage medium

Publications (1)

Publication Number Publication Date
CN117074666A true CN117074666A (en) 2023-11-17

Family

ID=88719041

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202311049839.XA Pending CN117074666A (en) 2023-08-18 2023-08-18 Test strip negative-positive identification method and device, electronic equipment and storage medium

Country Status (1)

Country Link
CN (1) CN117074666A (en)

Citations (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040043440A1 (en) * 2002-08-30 2004-03-04 Kermani Mahyar Z. Method and system for determining the acceptability of signal data collected from a prothrombin time test strip
US7489403B1 (en) * 2007-11-26 2009-02-10 Kaiwood Technology Co., Ltd. Electronic testing apparatus and testing method thereof
CN101650298A (en) * 2003-06-04 2010-02-17 因韦尔尼斯医药瑞士股份有限公司 Optical arrangement for assay reading device
CN104198695A (en) * 2014-09-28 2014-12-10 杨伟群 Method for analyzing developing result of colloidal gold test strip
US20150037898A1 (en) * 2012-04-19 2015-02-05 Roche Diagnostics Operations, Inc. Devices and methods of determining disturbance variable-corrected analyte concentrations
CN105143852A (en) * 2013-04-23 2015-12-09 秀根科技株式会社 Device for detecting analyzed object in specimen and method therefor
CN206208903U (en) * 2016-11-30 2017-05-31 黑龙江省科学院自动化研究所 A kind of colloid gold test paper adaptive background high resolution detection circuit
CN107561076A (en) * 2017-07-28 2018-01-09 武汉市安友泽瑞科技有限公司 The low cost optical electricity detecting system and method judged for the line color depth
CN109324039A (en) * 2017-07-31 2019-02-12 爱威科技股份有限公司 Test strips reaction density detection method, device, storage medium and computer equipment
CN110044883A (en) * 2019-04-07 2019-07-23 东莞市金翔光电科技有限公司 Immune quantitative analysis system color developing detection method
CN110187093A (en) * 2019-06-26 2019-08-30 上海艾瑞德生物科技有限公司 A kind of cross-platform detection device detecting fluorescence immunoassay and colloid gold reagent item
CN110579598A (en) * 2018-06-07 2019-12-17 江苏达骏生物科技有限公司 Optical signal detection device, system and method
US20200292539A1 (en) * 2019-03-14 2020-09-17 Quidel Corporation Result determination in an immunoassay by measuring kinetic slopes
CN112053299A (en) * 2020-08-27 2020-12-08 杭州安旭生物科技股份有限公司 Image processing method based on colloidal gold immunochromatography
CN113702633A (en) * 2020-05-22 2021-11-26 热起源控股股份有限公司 Lateral flow immunoassay test reader and method of use thereof
US20220084199A1 (en) * 2020-09-11 2022-03-17 Samsung Electronics Co., Ltd. Method for analyzing biomaterials based on image analysis and personalization data
CN114624208A (en) * 2022-05-13 2022-06-14 杭州中数信安科技有限公司 Test strip hemolysis determination and identification method based on red-green double spectrum
CN114674763A (en) * 2022-05-27 2022-06-28 杭州中数信安科技有限公司 Intelligent identification method and device for double-spectrum test strip
CN114910429A (en) * 2022-05-13 2022-08-16 杭州中数信安科技有限公司 Double-spectrum rapid screening device
CN114924068A (en) * 2022-05-13 2022-08-19 杭州中数信安科技有限公司 Rapid screening, detecting and analyzing system for high infectious diseases
CN115512136A (en) * 2022-08-26 2022-12-23 华南师范大学 Test paper color difference identification method and device, electronic equipment and storage medium

Patent Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040043440A1 (en) * 2002-08-30 2004-03-04 Kermani Mahyar Z. Method and system for determining the acceptability of signal data collected from a prothrombin time test strip
CN101650298A (en) * 2003-06-04 2010-02-17 因韦尔尼斯医药瑞士股份有限公司 Optical arrangement for assay reading device
US7489403B1 (en) * 2007-11-26 2009-02-10 Kaiwood Technology Co., Ltd. Electronic testing apparatus and testing method thereof
US20150037898A1 (en) * 2012-04-19 2015-02-05 Roche Diagnostics Operations, Inc. Devices and methods of determining disturbance variable-corrected analyte concentrations
CN105143852A (en) * 2013-04-23 2015-12-09 秀根科技株式会社 Device for detecting analyzed object in specimen and method therefor
CN104198695A (en) * 2014-09-28 2014-12-10 杨伟群 Method for analyzing developing result of colloidal gold test strip
CN206208903U (en) * 2016-11-30 2017-05-31 黑龙江省科学院自动化研究所 A kind of colloid gold test paper adaptive background high resolution detection circuit
CN107561076A (en) * 2017-07-28 2018-01-09 武汉市安友泽瑞科技有限公司 The low cost optical electricity detecting system and method judged for the line color depth
CN109324039A (en) * 2017-07-31 2019-02-12 爱威科技股份有限公司 Test strips reaction density detection method, device, storage medium and computer equipment
CN110579598A (en) * 2018-06-07 2019-12-17 江苏达骏生物科技有限公司 Optical signal detection device, system and method
CN113574384A (en) * 2019-03-14 2021-10-29 奎多公司 Determination of results in immunoassays by measuring kinetic slope
US20200292539A1 (en) * 2019-03-14 2020-09-17 Quidel Corporation Result determination in an immunoassay by measuring kinetic slopes
CN110044883A (en) * 2019-04-07 2019-07-23 东莞市金翔光电科技有限公司 Immune quantitative analysis system color developing detection method
CN110187093A (en) * 2019-06-26 2019-08-30 上海艾瑞德生物科技有限公司 A kind of cross-platform detection device detecting fluorescence immunoassay and colloid gold reagent item
CN113702633A (en) * 2020-05-22 2021-11-26 热起源控股股份有限公司 Lateral flow immunoassay test reader and method of use thereof
CN112053299A (en) * 2020-08-27 2020-12-08 杭州安旭生物科技股份有限公司 Image processing method based on colloidal gold immunochromatography
US20220084199A1 (en) * 2020-09-11 2022-03-17 Samsung Electronics Co., Ltd. Method for analyzing biomaterials based on image analysis and personalization data
CN114624208A (en) * 2022-05-13 2022-06-14 杭州中数信安科技有限公司 Test strip hemolysis determination and identification method based on red-green double spectrum
CN114910429A (en) * 2022-05-13 2022-08-16 杭州中数信安科技有限公司 Double-spectrum rapid screening device
CN114924068A (en) * 2022-05-13 2022-08-19 杭州中数信安科技有限公司 Rapid screening, detecting and analyzing system for high infectious diseases
CN114674763A (en) * 2022-05-27 2022-06-28 杭州中数信安科技有限公司 Intelligent identification method and device for double-spectrum test strip
CN115512136A (en) * 2022-08-26 2022-12-23 华南师范大学 Test paper color difference identification method and device, electronic equipment and storage medium

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
刘进: "基于视觉的三维建模相关技术研究", 中国优秀博硕士学位论文全文数据库 (硕士) 信息科技辑, no. 2, 15 December 2002 (2002-12-15) *
毕建伟: "基于CCD图像处理的胶体金试纸分析仪的设计", 中国优秀硕士学位论文全文数据库 工程科技Ⅱ辑, no. 4, 15 April 2017 (2017-04-15) *
汪曣等: "基于CCD的胶体金试纸条光电检测仪器设计及实验研究", 传感技术学报, no. 8, 31 August 2008 (2008-08-31), pages 1370 - 1373 *
王铁峰: "基于图像处理的金标试纸检测系统研究", 中国优秀硕士学位论文全文数据库 工程科技Ⅰ辑, no. 2, 15 February 2022 (2022-02-15) *
白玉洁: "胶体金试纸条的光电检测仪器研制", 中国优秀硕士学位论文全文数据库 农业科技辑, no. 8, 15 August 2009 (2009-08-15) *
詹铭: "基于STM32的金标卡定量检测系统的设计与实现", 中国优秀硕士学位论文全文数据库 工程科技Ⅱ辑, no. 1, 15 January 2021 (2021-01-15), pages 9 *

Similar Documents

Publication Publication Date Title
Kammarchedu et al. A machine learning-based multimodal electrochemical analytical device based on eMoSx-LIG for multiplexed detection of tyrosine and uric acid in sweat and saliva
Wan et al. Highly specific electrochemical analysis of cancer cells using multi‐nanoparticle labeling
Banez et al. Diagnostic potential of serum proteomic patterns in prostate cancer
JP6449449B2 (en) Sensor apparatus and method for determining chemical parameter values based on hue
AU2018233407B2 (en) Method for improving usability and accuracy for physiological measurement
JP2008129011A (en) Device for detecting contaminant in liquid, and system for using the same
US11913898B2 (en) System error compensation of analyte concentration determinations based on pseudo-reference concentration and signal-based anchor parameters
CN105022694B (en) Method for generating test case and system for mobile terminal test
WO2005085292A3 (en) Method for detecting the activatable free form of psa and the use thereof for diagnosing benign pathologies of the prostate and adenocarcinoma of the prostate
US20130034284A1 (en) Method of and system for enhanced dynamic range assay analysis
CN107580155A (en) Networking telephone quality determination method, device, computer equipment and storage medium
CN117074666A (en) Test strip negative-positive identification method and device, electronic equipment and storage medium
CN109444060B (en) Solution concentration detection method, device, equipment and storage medium
Pérez‐Accino et al. The utility of combined urine dipstick analysis and specific gravity measurement to determine feline proteinuria
Oh et al. Multiplexed single‐cell analysis of FNA allows accurate diagnosis of salivary gland tumors
Bristow et al. VOLTINT: A Matlab®-based program for semi-automated processing of geochemical data acquired by voltammetry
Steel et al. Cytohistological diagnosis of pancreatic serous cystadenoma: a multimodal approach
CN107315711A (en) A kind of adaptive exogenous variable recognition methods
Van der Linden Definition and classification of interferences in analytical procedures
CN116189807A (en) Nitrogen content intelligent monitoring system for nitrate preparation process
CN113379852B (en) Method, device, electronic equipment and medium for verifying camera calibration result
Chen et al. Deep learning-assisted sensitive detection of fentanyl using a bubbling-microchip
CN113761456A (en) Immunofluorescence chromatography curve analysis method and device and electronic equipment
Barrett et al. XRF analysis of historical paper in open books
CN113589394A (en) Method and equipment for identifying target detection object based on photoelectric sensor

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination