CN117064963A - Traditional Chinese medicine formula preparation for treating rhinitis and processing method thereof - Google Patents
Traditional Chinese medicine formula preparation for treating rhinitis and processing method thereof Download PDFInfo
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- CN117064963A CN117064963A CN202210500591.3A CN202210500591A CN117064963A CN 117064963 A CN117064963 A CN 117064963A CN 202210500591 A CN202210500591 A CN 202210500591A CN 117064963 A CN117064963 A CN 117064963A
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- chinese medicine
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- treating rhinitis
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of medical medicines, and discloses a traditional Chinese medicine formula preparation for treating rhinitis and a processing method thereof, wherein the traditional Chinese medicine formula preparation comprises the following components: radix Angelicae Dahuricae, rhizoma Belamcandae, flos Sophorae Immaturus, glycyrrhrizae radix and Borneolum Syntheticum are prepared from the above Chinese herbal medicines. The main effects are as follows: clearing heat and detoxicating, relieving sore throat, eliminating dampness and clearing lung-heat, removing blood stasis and resolving powder, cooling blood and stopping bleeding, dredging orifices, removing , and mainly treating nasosinusitis , nasal obstruction and nasal discharge, and various allergic rhinitis. The traditional Chinese medicine composition has the effects of diminishing inflammation, sterilizing, treating sore throat, resisting allergy, enhancing capillary resistance, resisting various inflammations and allergic reactions caused by histamine, reducing capillary fragility, eliminating focal free radicals, preventing inflammation and resisting inflammation, and the root cause of allergic rhinitis is local inflammation, the inflammation of throat and nasal cavity can be mutually involved, and a great deal of histamine is released from the nose part is stimulated, so that a series of allergic symptoms are caused.
Description
Technical Field
The invention belongs to the technical field of medical medicines, and in particular relates to a traditional Chinese medicine formula preparation for treating rhinitis and a processing method thereof.
Background
Rhinitis, i.e. inflammatory diseases of the nasal cavity, is an inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physicochemical factors and certain systemic diseases. The main pathological changes of rhinitis are nasal mucosa congestion, swelling, exudation, hyperplasia, atrophy or necrosis. The existing medicines for treating rhinitis are mostly western medicines, and in the actual treatment process of patients, the treatment period is long, the effect of treating both principal and secondary aspect of disease can not be achieved, and the medicines also have a plurality of adverse reactions, so that the use safety of the patients can not be ensured to a certain extent.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine formula preparation for treating rhinitis and a processing method thereof, which are used for solving the problems in the prior art in the background art.
In order to achieve the above purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine formula preparation for treating rhinitis, which comprises the following formula in terms of 1000ml of dosage, wherein: 12-20 g of angelica dahurica, 22-30 g of blackberry lily, 15-20 g of pagodatree flower bud, 6-10 g of liquorice, 1.2-2 g of borneol and the balance of water.
Preferably, the formulation is formulated as follows, in terms of 1000ml usage, wherein: 15 g of angelica dahurica, 26 g of blackberry lily, 16 g of pagodatree flower bud, 6 g of liquorice, 1.2 g of borneol and the balance of water.
Preferably, the formulation is formulated as follows, in terms of 1000ml usage, wherein: 18 g of angelica dahurica, 22 g of blackberry lily, 18 g of pagodatree flower bud, 8 g of liquorice, 1.5 g of borneol and the balance of water.
Preferably, the formulation is formulated as follows, in terms of 1000ml usage, wherein: 20 g of angelica dahurica, 30 g of blackberry lily, 20 g of pagodatree flower bud, 10 g of liquorice, 2 g of borneol and the balance of water.
A processing method of a traditional Chinese medicine formula preparation for treating rhinitis comprises the following steps:
s1, material taking: sequentially taking out radix Angelicae Dahuricae, rhizoma Belamcandae, flos Sophorae Immaturus, glycyrrhrizae radix, and Borneolum Syntheticum, and placing into corresponding containers;
s2, sorting: sequentially conveying the Chinese herbal medicines in the containers in the step S1 into an automatic sorting machine, screening the quality and the quality of the Chinese herbal medicines, and conveying the screened qualified products to a cleaning device;
s3, cleaning: uniformly placing the radix angelicae, blackberry lily, pagodatree flower bud and liquorice which are sorted in the step S2 into a herbal medicine cleaning machine, and cleaning up dust and impurities on the surfaces of the radix angelicae, blackberry lily, pagodatree flower bud and liquorice;
s4, decocting: feeding the Chinese herbal medicine cleaned in the step S3 into heating equipment, adding a proper amount of water, decocting for two times, wherein the first time is one hour, the second time is forty minutes, taking decoction, standing to remove sediment, filtering, adding 5% Tween 80 into filtrate, adding borneol for dissolution, and stirring;
s5, filling: quantitatively filling the liquid medicine obtained in the step S4 into nasal spray bottles by using filling equipment, wherein each bottle is 10ml;
s6, sticking: labeling the filled nasal spray bottle body with a label and marking a batch number;
s7, packaging and warehousing: the nasal spray is filled into the external inclusion, and the batch number is printed and stored in a warehouse.
Preferably, the Chinese medicine is decocted, precipitated and filtered, and a proper amount of cosolvent is added to increase the solvent degree of the effective components, and the transdermal absorption of the medicine by nasal mucosa is increased after the medicine is taken.
Preferably, the heating and decocting device in the step S4 is an automatic traditional Chinese medicine decocting machine, and the first time is one hour, and the second time is forty minutes.
The invention has the technical effects and advantages that: compared with the prior art, the traditional Chinese medicine formula preparation for treating rhinitis and the processing method thereof provided by the invention have the following advantages:
1. the Chinese medicinal intranasal spray prepared by sequentially taking out the angelica dahurica, blackberry lily, pagodatree flower bud, liquorice and borneol can be used for clearing heat and detoxicating, relieving sore throat, eliminating dampness and clearing lung-heat, removing stasis and dispersing, cooling blood and stopping bleeding, dredging orifices, removing nasal obstruction , and mainly treating nasosinusitis , nasal obstruction and nasal discharge and various allergic rhinitis. The composition has antiinflammatory, antibacterial, sore throat relieving, antiallergic, capillary resistance improving, and antihistamine-induced inflammation and anaphylaxis resisting effects;
2. compared with the existing western medicines for treating rhinitis, the traditional Chinese medicine composition is prepared by adopting a Chinese herbal medicine mode, has the advantages of unique conception, no toxic or side effect, safe and reliable administration, obvious curative effect and treatment effect on both symptoms and root causes, and is beneficial to shortening the treatment period of patients and reducing the recurrence rate.
Drawings
Fig. 1 is a flow chart of a processing method of a traditional Chinese medicine formula preparation for treating rhinitis.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. The specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
The invention provides a technical scheme that: a traditional Chinese medicine formula preparation for treating rhinitis is prepared from the following components in parts by mass: 15 g of angelica dahurica, 26 g of blackberry lily, 16 g of pagodatree flower bud, 6 g of liquorice, 1.2 g of borneol and the balance of water, and the total volume of the preparation is 1000ml.
The processing method of the traditional Chinese medicine for treating rhinitis comprises the following steps:
s1, material taking: sequentially taking out radix Angelicae Dahuricae, rhizoma Belamcandae, flos Sophorae Immaturus, glycyrrhrizae radix, borneolum Syntheticum, and various Chinese herbal medicines, and placing into corresponding containers;
s2, sorting: sorting the Chinese herbal medicines in each container in the step S1, screening the quality and the quality of the Chinese herbal medicines, and then reserving the screened qualified products;
s3, decocting: and (3) placing the Chinese herbal medicines sorted in the step S2 into a decocting machine. Decocting for two times, one hour at a time and forty minutes at a time.
S4, preparing: mixing the two decoctions in step S3, standing, removing precipitate, adding Tween 8050ml, and adding water to 1000ml.
S5, filling: and (3) filling the liquid medicine in the step S4 into nasal cavity spray bottles by using filling equipment, wherein each bottle is 10ml.
S6, packaging: and (5) labeling the filled nasal spray, and filling the nasal spray into an external inclusion.
S7, warehousing: and marking the batch number outside the packaged medicine, and storing the medicine in a warehouse.
The nasal cavity spray for treating rhinitis is used twice a day, each nasal cavity sprays twice,
in addition, the step S3 decocting equipment is an automatic decocting machine, and the step S6 filling equipment is a liquid semi-automatic filling machine.
Example 2
The invention provides a technical scheme that: a traditional Chinese medicine formula preparation for treating rhinitis is prepared from the following components in parts by mass: 18 g of dahurian angelica root, 22 g of blackberry lily, 18 g of pagodatree flower bud, 8 g of liquorice, 1.5 g of borneol and the balance of water, and the total volume of the preparation is 1000ml.
The processing method of the traditional Chinese medicine preparation for treating rhinitis comprises the following steps:
s1, material taking: sequentially taking out radix Angelicae Dahuricae, rhizoma Belamcandae, flos Sophorae Immaturus, glycyrrhrizae radix, borneolum Syntheticum, and various Chinese herbal medicines, and placing into corresponding containers;
s2, sorting: sorting the Chinese herbal medicines in each container in the step S1, screening the quality and the quality of the Chinese herbal medicines, and then reserving the screened qualified products;
s3, decocting: and (3) placing the Chinese herbal medicines sorted in the step S2 into a decocting machine. Decocting for two times, one hour at a time and forty minutes at a time.
S4, preparing: mixing the two decoctions in step S3, standing, removing precipitate, adding Tween 8050ml, and adding water to 1000ml.
S5, filling: and (3) filling the liquid medicine in the step S4 into nasal cavity spray bottles by using filling equipment, wherein each bottle is 10ml.
S6, packaging: and (5) labeling the filled nasal spray, and filling the nasal spray into an external inclusion.
S7, warehousing: sealing the split-packed medicament bags by using a heat sealing machine, and storing the split-packed medicament bags in a warehouse. The nasal spray for treating rhinitis is used twice daily, and each nasal spray is sprayed twice.
In addition, the decocting device in the step S3 is a traditional Chinese medicine automatic decocting machine, and the filling device in the step S4 is a semi-automatic liquid filling machine.
Example 3
The invention provides a technical scheme that: a traditional Chinese medicine formula preparation for treating rhinitis is prepared from the following components in parts by mass: 20 g of angelica dahurica, 30 g of blackberry lily, 20 g of pagodatree flower bud, 10 g of liquorice, 2 g of borneol and the balance of water, and the total volume of the preparation is 1000ml.
The processing method of the traditional Chinese medicine for treating rhinitis comprises the following steps:
s1, material taking: sequentially taking out radix Angelicae Dahuricae, rhizoma Belamcandae, flos Sophorae Immaturus, glycyrrhrizae radix, borneolum Syntheticum, and various Chinese herbal medicines, and placing into corresponding containers;
s2, sorting: sorting the Chinese herbal medicines in each container in the step S1, screening the quality and the quality of the Chinese herbal medicines, and then reserving the screened qualified products;
s3, decocting: and (3) placing the Chinese herbal medicines sorted in the step S2 into a decocting machine. Decocting for two times, one hour at a time and forty minutes at a time.
S4, preparing: mixing the two decoctions in step S3, standing, removing precipitate, adding Tween 8050ml, and adding water to 1000ml.
S5, filling: and (3) filling the liquid medicine in the step S4 into nasal cavity spray bottles by using filling equipment, wherein each bottle is 10ml.
S6, packaging: and (5) labeling the filled nasal spray, and filling the nasal spray into an external inclusion.
S7, warehousing: sealing the split-packed medicament bags by using a heat sealing machine, and storing the split-packed medicament bags in a warehouse.
The nasal cavity spray for treating rhinitis is used twice a day, each nasal cavity sprays twice,
in addition, the step S3 decocting equipment is an automatic decocting machine, and the step S6 filling equipment is a liquid semi-automatic filling machine.
The drug effect attributes of the traditional Chinese medicine components in the invention are respectively as follows:
radix angelicae: for exterior syndrome due to exogenous wind-cold, headache, nasal obstruction and nasal discharge, headache due to yang, bone pain, headache due to wind-cold, etc., it can be used singly or in combination.
Zhi Gao is bitter in flavor, cold in nature and enters lung meridian. Has effects of purging pathogenic fire, removing toxic substances, eliminating phlegm, relieving sore throat, etc. It is mainly used for treating excessive phlegm stagnation due to heat toxin, sore throat, excessive phlegm and saliva, cough and asthma, etc. The "compendium of materia Medica" carries: belamcanda rhizome, rhizoma Belamcandae, can lower pathogenic fire, so ancient Fang Zhi, sore throat and throat are the key herbs. Sun Zhenren in Qian jin Fang (Qian jin Fang) there is Wu ointment for treating pharyngitis. Clearing heat and detoxicating; eliminating phlegm and relieving sore throat; remove blood stasis and dissipate nodulation. Swelling and pain of the main throat; cough and asthma; scrofula tuberculosis; the malaria mother's obstruction; carbuncle, swelling and sore. Is used for treating heat toxin and phlegm fire stagnation, sore throat, excessive phlegm and saliva, cough and asthma. Book of changes: the cough with the primary cough with the adverse rise of qi, the sore throat and the inflammation of the throat are eliminated, and the cure of allergic rhinitis is facilitated.
Modern medicine has studied blackberry lily, and the blackberry lily is considered to have antiviral, anti-inflammatory, bactericidal, antipyretic, analgesic and other effects. The latest research on blackberry lily at present has the effects of reducing blood pressure, resisting tumors and pagodatree flower bud 1, the pagodatree flower bud can reduce blood pressure and prevent stroke: rutin (rutin) contained in flos Sophorae Immaturus is a vitamin with effects of enhancing capillary resistance, improving blood vessel wall elasticity, improving toughness of capillary, preventing cerebral vascular rupture of hypertension patients, and preventing apoplexy. 2. The pagodatree flower bud can cool blood and stop bleeding: the flos Sophorae Immaturus is mainly used for treating hemorrhage due to blood heat, and can be combined with radix Sangusorbae for treating lower hemorrhage such as hematochezia, haematuria, hemorrhoid, etc. 3. The flos Sophorae Immaturus has antiinflammatory effect: has obvious inhibiting effect on the inflammatory process of the implanted sheep wool ball. 4. The pagodatree flower bud has the effects of eliminating phlegm, relieving cough and the like: quercetin contained in the product has a certain effect of relieving asthma. In addition, the blood pressure is reduced, the resistance of the capillary vessel is enhanced, the fragility of the capillary vessel is reduced, and free radicals in the body are removed: quercetin is a substance extracted from Quercetin, and Quercetin can effectively resist oxidation process of human body, and has anti-inflammatory effect: the quercetin has high medicinal value, has good antagonism effect on inflammation, serious harm to human body after inflammation infection, influences navigation of digestive system and respiratory system, skin mucous membrane, blood and the like, and most of inflammation in the human body is mainly caused by high values of cyclooxygenase and phytase of the human body, the quercetin can play a role in inhibiting diffusion of inflammatory cells after being taken, and meanwhile, the quercetin has the effects of preventing inflammation and resisting inflammation, and the pagodatree flower bud can clear allergic inflammation of nasal cavity, lighten and prevent allergy, repair diseased nasal mucous membrane and reduce recurrence rate.
Borneol: compendium of materia Medica: treating pharyngitis, brain pain, nasal , odontalgia, typhoid tongue appearance and infantile acne. Unblocking orifices and dispelling stagnated fire. "" medical compilation: borneol is used for dispelling stagnated fire, and can be used for treating convulsion epilepsy, phlegm, pharyngitis, tongue distention, toothache, deafness, nasal obstruction, conjunctival congestion, nebula, acne, invasion of toxin, disinfestation, hemorrhoid, promoting tissue regeneration, promoting sexual travel, promoting tissue regeneration and relieving pain.
Glycyrrhrizae radix has corticoid-like effect, and has good effect on various allergies caused by histamine. The licorice has the main effects of invigorating spleen and replenishing qi, clearing heat and detoxicating, eliminating phlegm and relieving cough, relieving spasm and pain and harmonizing various medicines, and is used for treating weakness of spleen and stomach, lassitude and hypodynamia, palpitation and shortness of breath, cough with excessive phlegm, gastric and abdominal pain, limb spasm and pain, carbuncle swelling and sore toxin and relieving toxic taste of medicines.
In examples 1-3, the proportions of the components are as follows:
clinical use and case analysis:
1. clinical data: randomly selecting 20 patients, wherein the ages of the patients are 20-60 years, and the patients are divided into two groups, one group is a male patient group, the other group is a female patient group, wherein 10 men are 10 women and 10 women are 10 women. 2. Clinical diagnostic criteria: the nasal cavity is sprayed once in the morning and evening every day, and each two sprays are divided into 3 treatment courses, and one treatment course is 1 week. The symptoms in one course of treatment are obviously improved, the symptoms are effective, the symptoms are ineffective if no obvious change exists in 2 courses of treatment, and the symptoms are healed if no symptoms exist after 3 courses of treatment.
The result shows that the medicine is safe and reliable, the curative effect is obvious, the recurrence rate after healing is low, the effect of treating both principal and secondary aspect of disease is achieved, and other adverse reactions are not seen except for transient local irritation after use.
Typical case 1
Yang Mou it is used for men, and is used for 29 years old for treating allergic rhinitis, pharyngalgia, nasal membrane swelling, pale tongue, pruritus, nasal obstruction, nasal discharge, dizziness, and smoking and drinking, and has no effect on daily life and work. Hormones and drugs for contracting nasal mucosa have been used more severely. The symptoms are relieved after one week after the preparation is used. Nasal cavity ventilation is carried out after ten days, nasal discharge is avoided, and after two weeks, the nasal discharge is cured, the nasal discharge is dared to smoke and drink, and the nasal discharge recurs until now.
Typical case 2
Chang Mou and 56 years old women, and are diagnosed with allergic rhinitis, pharyngalgia, turbinate swelling, pale tongue, itching, nasal obstruction and running nose, and the broom-like quilt can cause acute onset of allergic rhinitis for more than ten years. Four days after the preparation is used, the feeling is improved, the dry housework is not influenced after one week, and the preparation is cured after three weeks of treatment.
Typical case 3
Wang Mou after 43 years of age, the symptoms of allergic rhinitis, pharyngalgia, turbinate swelling, pale tongue, itching, nasal obstruction, running nose and headache are eliminated after two treatment courses of the traditional Chinese medicine preparation.
Notice that:
1. is forbidden for pregnant women.
2. During the treatment period, the wine and the smoke are forbidden and the light diet is matched.
Is prepared from radix Angelicae Dahuricae, rhizoma Belamcandae, flos Sophorae Immaturus, glycyrrhrizae radix and Borneolum Syntheticum by mixing the above Chinese medicinal materials. The main effects are as follows: clearing heat and detoxicating, relieving sore throat, eliminating dampness and clearing lung-heat, removing blood stasis and resolving powder, cooling blood and stopping bleeding, dredging orifices, removing , and mainly treating nasosinusitis , nasal obstruction and nasal discharge, and various allergic rhinitis. The traditional Chinese medicine composition has the effects of diminishing inflammation, sterilizing, treating sore throat, resisting allergy, enhancing capillary resistance, resisting various inflammations and allergic reactions caused by histamine, reducing capillary fragility, eliminating focal free radicals, preventing inflammation and resisting inflammation, and the root cause of allergic rhinitis is local inflammation, the inflammation of throat and nasal cavity can be mutually involved, and a great deal of histamine is released from the nose part is stimulated, so that a series of allergic symptoms are caused. The composition has effects in clearing away heat and toxic materials, relieving inflammation, resisting allergy, and repairing pathological nasal mucosa. The blackberry lily which is a good medicament for relieving sore throat is reused in the prescription, so that the blackberry lily has very good treatment effect on nasal inflammation. Compared with the traditional Chinese and western medicines commonly used at present, the prescription has the advantages of quick curative effect, low recurrence rate after healing, unique conception, no toxic or side effect, safe and reliable medicine application, obvious curative effect, and achieves the effect of treating both symptoms and root causes, thereby being beneficial to shortening the treatment period of patients.
Finally, it should be noted that: the foregoing description is only illustrative of the preferred embodiments of the present invention, and although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements or changes may be made without departing from the spirit and principles of the present invention.
Claims (7)
1. A traditional Chinese medicine formula preparation for treating rhinitis is characterized in that: the formulation was formulated as follows, in terms of 1000ml usage, wherein: 12-20 g of angelica dahurica, 22-30 g of blackberry lily, 15-20 g of pagodatree flower bud, 6-10 g of liquorice, 1.2-2 g of borneol and the balance of water.
2. The traditional Chinese medicine formula preparation for treating rhinitis according to claim 1, which is characterized in that: the formulation was formulated as follows, in terms of 1000ml usage, wherein: 15 g of angelica dahurica, 26 g of blackberry lily, 16 g of pagodatree flower bud, 6 g of liquorice, 1.2 g of borneol and the balance of water.
3. The traditional Chinese medicine formula preparation for treating rhinitis according to claim 1, which is characterized in that: the formulation was formulated as follows, in terms of 1000ml usage, wherein: 18 g of angelica dahurica, 22 g of blackberry lily, 18 g of pagodatree flower bud, 8 g of liquorice, 1.5 g of borneol and the balance of water.
4. The traditional Chinese medicine formula preparation for treating rhinitis according to claim 1, which is characterized in that: the formulation was formulated as follows, in terms of 1000ml usage, wherein: 20 g of angelica dahurica, 30 g of blackberry lily, 20 g of pagodatree flower bud, 10 g of liquorice, 2 g of borneol and the balance of water.
5. A method for processing a traditional Chinese medicine formula preparation for treating rhinitis, comprising the traditional Chinese medicine formula preparation for treating rhinitis according to any one of claims 1 to 4, and the method is characterized by comprising the following steps:
s1, material taking: sequentially taking out radix Angelicae Dahuricae, rhizoma Belamcandae, flos Sophorae Immaturus, glycyrrhrizae radix, and Borneolum Syntheticum, and placing into corresponding containers;
s2, sorting: sequentially conveying the Chinese herbal medicines in the containers in the step S1 into an automatic sorting machine, screening the quality and the quality of the Chinese herbal medicines, and conveying the screened qualified products to a cleaning device;
s3, cleaning: uniformly placing the radix angelicae, blackberry lily, pagodatree flower bud and liquorice which are sorted in the step S2 into a herbal medicine cleaning machine, and cleaning up dust and impurities on the surfaces of the radix angelicae, blackberry lily, pagodatree flower bud and liquorice;
s4, decocting: feeding the Chinese herbal medicine cleaned in the step S3 into heating equipment, adding a proper amount of water, decocting for two times, wherein the first time is one hour, the second time is forty minutes, taking decoction, standing to remove sediment, filtering, adding 5% Tween 80 into filtrate, adding borneol for dissolution, and stirring;
s5, filling: quantitatively filling the liquid medicine obtained in the step S4 into nasal spray bottles by using filling equipment, wherein each bottle is 10ml;
s6, sticking: labeling the filled nasal spray bottle body with a label and marking a batch number;
s7, packaging and warehousing: the nasal spray is filled into the external inclusion, and the batch number is printed and stored in a warehouse.
6. The processing method according to claim 5, wherein: the Chinese medicine is decocted, precipitated and filtered, and proper amount of cosolvent is added to increase the solvent degree of the effective components, and the transdermal absorption of the medicine by nasal mucosa is increased after the medicine is taken.
7. The processing method according to claim 5, wherein: the heating and decocting device in the step S4 is an automatic traditional Chinese medicine decocting machine, and the first time is one hour, and the second time is forty minutes.
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