CN1170582A - Chinese drug for curing and preventing mastosis and its preparing method - Google Patents

Chinese drug for curing and preventing mastosis and its preparing method Download PDF

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CN1170582A
CN1170582A CN96107177A CN96107177A CN1170582A CN 1170582 A CN1170582 A CN 1170582A CN 96107177 A CN96107177 A CN 96107177A CN 96107177 A CN96107177 A CN 96107177A CN 1170582 A CN1170582 A CN 1170582A
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radix
rhizoma
chinese medicine
fructus
pericarpium citri
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CN1060664C (en
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鲍旭东
鲍树伟
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Abstract

The said Chinese drug includes medicinal powder comprising Radix Bupleuri, Rhizoma cyperi, selfheal, orange peel, Pericarpium Citri Reticulatae Viride and other 23 kinds of Chinese medicinal materials and medicinal liquid comprising the extraction of pangolin scales, Fructus tichosanthis, Radix Paeoniae Alba, safflower, fritilary and other 15 kinds of Chinese medicinal materials. The present invention also provides the preparation process of the said Chinese drug.

Description

The Chinese medicine and the method for making thereof of treatment and prevention mastopathy
The present invention relates to Chinese medicine of a kind of treatment and prevention mastopathy and preparation method thereof.
Mastopathy is a big disease of the vast WomanHealth of current harm, and the lighter's distending pain of the breast is not healed for many years; Weight person suffers from cyclomastopathy, and even breast carcinoma takes place, thus harm people's life.Yet, though current Therapeutic Method has the positive therapeutic effect, mostly cumbersome complexity, not easy, the patient is difficult for persevering, recurrence easily again after the drug withdrawal.Particularly, also there are not simple, prolonged application, effective prevention method at present to the generation of prevention mastopathy.
Therefore, in order to overcome above-mentioned the deficiencies in the prior art, purpose of the present invention promptly is to provide the Chinese medicine of a kind of treatment and prevention mastopathy, consider the efficacy of a drug difference of the outer time spent performance of various Chinese crude drugs, selected medical material is divided into two groups, one group is used with powdery form, and other forms with its extract are used, to give full play to the effectiveness of medicine.
The present invention also provides the method for the described Chinese medicine of preparation, and the application of described Chinese medicine.
The Chinese medicine of the present invention's treatment and prevention mastopathy mainly comprises following composition: Radix Bupleuri, Rhizoma Cyperi, Spica Prunellae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, trifoliate orange are prominent, Fructus Aurantii, the Radix Aucklandiae, Rhizoma Chuanxiong, Olibanum, Radix Curcumae, Lignum Dalbergiae Odoriferae, Radix Angelicae Sinensis, rhizoma sparganic, ZHONGBANGZI, Myrrha, Radix Rhapontici, Semen Vaccariae, Radix Salviae Miltiorrhizae, Thallus Laminariae (Thallus Eckloniae), Fructus Toosendan, Spina Gleditsiae, Herba Leonuri, Fructus Liquidambaris, Sargassum, Flos Rosae Chinensis, Flos Rosae Rugosae, Concha Arcae, Squama Manis, Chinese juniper beach wormwood, the Radix Paeoniae Alba, Flos Carthami, Bulbus Fritillariae Thunbergii, Rhizoma Curcumae, Rhizoma Corydalis and Retinervus Luffae Fructus.
Particularly, the Chinese medicine of described treatment and prevention mastopathy comprises (percentage by weight):
(1), by the Radix Bupleuri 4-8 that pulverizes, Rhizoma Cyperi 3-16, Spica Prunellae 2-5, Pericarpium Citri Reticulatae 1-4, Pericarpium Citri Reticulatae Viride 3-7, the trifoliate orange 3-7 that dashes forward, Fructus Aurantii 1-4, Radix Aucklandiae 3-6, Rhizoma Chuanxiong 3-7, Olibanum 3-6, Radix Curcumae 3-6, Lignum Dalbergiae Odoriferae 2-6, Radix Angelicae Sinensis 3-7, rhizoma sparganic 3-6, Radix Rhapontici 3-7, BANBANGZI 3-7, Semen Vaccariae 3-7, Fructus Toosendan 2-4, Spina Gleditsiae 2-6, Thallus Laminariae (Thallus Eckloniae) 2-6, Radix Salviae Miltiorrhizae 1-3.5, Herba Leonuri 3-6, Sargassum 3-6, Fructus Liquidambaris 1.5-4, Flos Rosae Chinensis 0.5-3, Flos Rosae Rugosae 0.5-3, the component A that Concha Arcae 3-5 forms; And,
(2) comprise Squama Manis 5-10, Chinese juniper beach wormwood 4-9, Radix Paeoniae Alba 1-4, Flos Carthami 1-4, Bulbus Fritillariae Thunbergii 1-4, Rhizoma Curcumae 4-8, Rhizoma Corydalis 4-8, Retinervus Luffae Fructus 4-8, Sargassum 4-8, Myrrha 4-8, Rhizoma Chuanxiong 4-9, Radix Aucklandiae 4-9, Radix Rhapontici 2-5, Thallus Laminariae (Thallus Eckloniae) 4-8, Pericarpium Citri Reticulatae Viride 2.5-7, Semen Vaccariae 4-10, Fructus Liquidambaris 4-10, the trifoliate orange 2.5-7 that dashes forward, Radix Bupleuri 4-8 and Concha Arcae 4-8 water extract and 75% ethanol are with 1: 1.5-1: 4 weight ratio is mixed the B component of the mixture of back gained.
In above-mentioned Chinese medicine, described water extract is meant that the medical material of described weight ratio decocts the medicinal liquid to obtain after the solvable composition of abundant dissolving in water.The water extraction of Chinese medicine is that those skilled in the art is known, and the mode that decocts with water as utilization can realize.
The present invention further provides a kind of method for preparing the Chinese medicine of treatment and prevention mastopathy, comprise the steps:
(1), pulverizing weight ratio is following medical material: Radix Bupleuri 4-8, Rhizoma Cyperi 3-16, Spica Prunellae 2-5, Pericarpium Citri Reticulatae 1-4, Pericarpium Citri Reticulatae Viride 3-7, the trifoliate orange 3-7 that dashes forward, Fructus Aurantii 1-4, Radix Aucklandiae 3-6, Rhizoma Chuanxiong 3-7, Olibanum 3-6, Radix Curcumae 3-6, Lignum Dalbergiae Odoriferae 2-6, Radix Angelicae Sinensis 3-7, rhizoma sparganic 3-6, Radix Rhapontici 3-7, BANBANGZI 3-7, Semen Vaccariae 3-7, Fructus Toosendan 2-4, Spina Gleditsiae 2-6, Thallus Laminariae (Thallus Eckloniae) 2-6, Radix Salviae Miltiorrhizae 1-3.5, Herba Leonuri 3-6, Sargassum 3-6, Fructus Liquidambaris 1.5-4, Flos Rosae Chinensis 0.5-3, Flos Rosae Rugosae 0.5-3, Concha Arcae 3-5, the component A of composition;
(2) water decocts Squama Manis 5-10, Fructrs Trichosanthis 4-9, Radix Paeoniae Alba 1-4, Flos Carthami 1-4, Bulbus Fritillariae Thunbergii 1-4, Rhizoma Curcumae 4-8, Rhizoma Corydalis 4-8, Retinervus Luffae Fructus 4-8, Sargassum 4-8, Myrrha 4-8, Rhizoma Chuanxiong 4-9, Radix Aucklandiae 4-9, Radix Rhapontici 2-5, Thallus Laminariae (Thallus Eckloniae) 4-8, Pericarpium Citri Reticulatae Viride 2.5-7, Semen Vaccariae 4-10, Fructus Liquidambaris 4-10, the trifoliate orange 2.5-7 that dashes forward, Radix Bupleuri 4-8 and Concha Arcae 4-8, fully dissolving solvable composition wherein obtains water extract; Cooling, clarification back and 75% ethanol are with 1: 1.5-1: 4 weight ratio is mixed, after leaving standstill and clarifying B component.
The present invention further provides above-mentioned Chinese medicine, the application in the medicine of preparation treatment and prevention mastopathy.Wherein, described mastopathy comprises periodically or persistence distending pain of the breast, breast dysplasia, mastatrophy and cyclomastopathy.
The present invention further provides the medicated cushion of a kind of treatment and prevention mastopathy, comprise a cloth pad that medicated bra is cup-shaped, the component A of above-mentioned Chinese medicine places the interlayer of described cloth pad, described B component drip cloth pad inboard on the snack made with traditional Chinese medicines.Four meridian points of the corresponding Chinese traditional treatment mastopathy of described snack made with traditional Chinese medicines.
In the selected medical material of the present invention, selected Radix Bupleuri, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae, trifoliate orange are prominent, Fructus Aurantii, the Radix Aucklandiae, Fructus Toosendan be with soothing liver-QI for relieving depression, promoting the circulation of QI to relieve pain, lactogenesis relieving distension, the eliminating stagnation painful abdominal mass that disappears; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Rhizoma Corydalis, Radix Salviae Miltiorrhizae, Herba Leonuri, Flos Carthami, Flos Rosae Chinensis, Flos Rosae Rugosae, Radix Curcumae, Lignum Dalbergiae Odoriferae with nourshing blood and promoting blood circulation, transfer mend appoint dash, menstruction regulating and pain relieving, blood stasis-eliminating and stagnation-dissipating; The Radix Paeoniae Alba is with the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain; Sargassum, Thallus Laminariae (Thallus Eckloniae), Concha Arcae disappear to reduce phlegm painful abdominal mass, hard masses softening and resolving; Radix Rhapontici, Fructus Arctii are with detoxifcation lactogenesis, mass dissipating and swelling eliminating; Spica Prunellae is with lung heat clearing eliminating stagnation, antiinflammatory disease; Squama Manis, Semen Vaccariae are with the lactogenesis of invigorating blood circulation, the network that the relaxes painful abdominal mass that disappears; Rhizoma sparganic, Rhizoma Curcumae, Myrrha, Olibanum with promoting blood circulation and breaking stagnation, promoting the circulation of QI to relieve pain, Bulbus Fritillariae Thunbergii, Retinervus Luffae Fructus with wide born of the same parents painful abdominal mass, the lactogenesis pain that disappears that disappears of regulating the flow of vital energy, reduce phlegm; Fructus Liquidambaris is with the lactogenesis network that relaxes; Spina Gleditsiae disappears to invigorate blood circulation bitterly, detoxifcation.
Thereby the Chinese medicine of the present invention's treatment and prevention mastopathy has the effect of removing painful abdominal mass in Shu Hangqi, blood circulation promoting and blood stasis dispelling, tonifying Chong and Ren channels, dredging the meridian, lactogenesis eliminating stagnation, pain relieving relieving distension, change disease softening the hard mass, antiinflammatory.Its to periodically distending pain of the breast or persistence distending pain of the breast, menalgia, menoxenia of women, the cycle is indefinite, emotion is impetuous or gloomy, headache, costalgia, breast dysplasia etc. have excellent effect.Treatment cyclomastopathy or the alleviation pain that hypertrophy occurred also there is significant curative effect.Particularly prolonged application or the interim skin disease of using prevention cyclomastopathy, breast carcinoma can play positive preventive and therapeutic effect.
Because the Chinese medicine of the present invention's treatment and prevention mastopathy mainly is external, so, it is divided into two parts, the one, the abnormal smells from the patient virtue is hot, the comparatively ideal medicine of Transdermal absorption is made powder, puts into medicated cushion and carries out Transdermal absorption; And it is medicine matter is hard or the flavour of a drug Transdermal absorption is undesirable, must processing extract Fang Yi and absorb, make medicinal liquid and soak into absorption but to be this sick indispensable medicine of treatment such as Squama Manis, Fructrs Trichosanthis, Rhizoma Corydalis, Myrrha, Retinervus Luffae Fructus, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Radix Paeoniae Alba, Flos Carthami etc. by processing extract.The immersion of medicinal liquid not only has stronger infiltration Absorption, and has strengthened the drug transdermal absorbability in the medicated cushion, and has played the effect of carrier for simultaneously the drug transdermal absorption in the medicated cushion, thereby has improved curative effect greatly.
Above-mentioned Chinese medicine not only has independently therapeutical effect to disease, and simple and convenient, no pain, has no side effect, and the patient very easily accepts, but and prolonged application, play the effect of positive prevention morbidity.
As the drug powder in the medicated cushion of component A, its method for making is processed into powder for breaking method routinely with above-mentioned each composition, mixes getting final product then by said ratio.
And the method for making of described medicinal liquid is, said medicine is placed earth pot, adds water and does not have medical material, decocted 25 minutes, and took out medicinal liquid, add water again and do not have medical material, decocted 25 minutes, the levigation medicinal liquid is with the medicinal liquid mixing of above-mentioned twice decoction, filter three times with filter paper cooling back, adds 75% ethanol then and filter, and 75% ethanol and medicinal liquid ratio are 1: 1.5-1: 4, preferred 1: 2.5, leave standstill in the close device blood of envelope, the clarification back is extracted yellowish colour purity clear liquid and is made medicinal liquid, is B component of the present invention.
The usage of the Chinese medicine of the present invention's treatment and prevention mastopathy is:
The drug powder as in the medicated cushion that 20g is above-mentioned is put into textile and is knitted the medicated bag that calico is made, and makes medicated cushion.The black cotton textiles are weaved cotton cloth is cut into four circular piece, and a sewing is on the central point of medicated cushion inboard, and it, is made four meridian points and snack made with traditional Chinese medicines below the central point of medicated cushion inboard in three equidistant sewing.With external medicinal liquid splash into four meridian points on the medicated cushion on the snack made with traditional Chinese medicines, each snack made with traditional Chinese medicines and drips medicine 4-5 and drip, jede Woche drips medicine and is no less than 4 times, every auxiliary medicine pad used one month, three months is to use round the clock a course of treatment.The prevent disease user can interim be used, and every auxiliary medicine pad should use two months, but also jede Woche dropping liquid 1-2 time of medicinal liquid.
The present invention is described in detail below in conjunction with embodiment, but should not be construed as limitation of the present invention.Embodiment 1
Get Radix Bupleuri 2.58g, Rhizoma Cyperi 1.94g, Spica Prunellae 1.29g, Pericarpium Citri Reticulatae 0.65g, Pericarpium Citri Reticulatae Viride 1.94g, the trifoliate orange 1.94g that dashes forward, Fructus Aurantii 0.65g, Radix Aucklandiae 1.94g, Rhizoma Chuanxiong 1.94g, Olibanum 1.94g, Radix Curcumae 1.94g, Lignum Dalbergiae Odoriferae 1.29g, Radix Angelicae Sinensis 1.94g, rhizoma sparganic 1.94g, Radix Rhapontici 1.94g, BANBANGZI 1.94g, Semen Vaccariae 1.94g, Fructus Toosendan 1.29g, Spina Gleditsiae 1.29g, Thallus Laminariae (Thallus Eckloniae) 1.29g, Radix Salviae Miltiorrhizae 0.65g, Herba Leonuri 1.94g, Sargassum 1.94g, Fructus Liquidambaris 0.97g, Flos Rosae Chinensis 0.32g, Flos Rosae Rugosae 0.32g, Concha Arcae 1.94g.Above-mentioned each composition is processed into powder with conventional breaking method, mixes by above-mentioned weight proportion then.
Take by weighing each composition by following weight: Squama Manis 3.35g, Fructrs Trichosanthis 2.68g, Radix Paeoniae Alba 0.67g, Flos Carthami 0.67g, Bulbus Fritillariae Thunbergii 0.67g, Rhizoma Curcumae 2.68g, Rhizoma Corydalis 2.68g, Retinervus Luffae Fructus 2.68g, Sargassum 2.68g, Myrrha 2.68g, Rhizoma Chuanxiong 2.68g, Radix Aucklandiae 2.68g, Radix Rhapontici 1.34g, Thallus Laminariae (Thallus Eckloniae) 2.68g, Pericarpium Citri Reticulatae Viride 1.68g, Semen Vaccariae 2.68g, Fructus Liquidambaris 2.68g, trifoliate orange dash forward 1.68g, Radix Bupleuri 2.68g and Concha Arcae 2.68g.
Above-mentioned each composition is placed earth pot, decoct with water 25 minutes, take out medicinal liquid, decoct with water 25 minutes again, the levigation medicinal liquid, the medicinal liquid of above-mentioned twice decoction is mixed, filter three times with filter paper cooling back, adds 75% ethanol then and filter, and medicinal liquid and 75% alcoholic acid ratio are 1: 2.5, leave standstill in the close device blood of envelope, the clarification back is extracted yellowish colour purity clear liquid and is made medicinal liquid.Embodiment 2
Repeat the step of embodiment 1, difference is that the consumption of various medical materials is different.
Comprise (percentage by weight) as the drug powder in the medicated cushion: Radix Bupleuri 13g, Rhizoma Cyperi 26g, Spica Prunellae 8.13g, Pericarpium Citri Reticulatae 6.50g, Pericarpium Citri Reticulatae Viride 11.38g, the trifoliate orange 11.38g that dashes forward, Fructus Aurantii 6.50g, Radix Aucklandiae 9.75g, Rhizoma Chuanxiong 11.38g, Olibanum 9.75g, Radix Curcumae 9.75g, Lignum Dalbergiae Odoriferae 9.75g, Radix Angelicae Sinensis 11.38g, rhizoma sparganic 9.75g, Radix Rhapontici 11.38g, BANBANGZI 11.38g, Semen Vaccariae 11.38g, Fructus Toosendan 6.50g, Spina Gleditsiae 9.75g, Thallus Laminariae (Thallus Eckloniae) 9.75g, Radix Salviae Miltiorrhizae 5.69g, Herba Leonuri 9.75g, Sargassum 9.75g, Fructus Liquidambaris 6.50g, Flos Rosae Chinensis 4.88g, Flos Rosae Rugosae 4.88g, Concha Arcae 8.13g.With the method identical above-mentioned composition is made mixture of powders with embodiment 1.
And comprise (percentage by weight) as the medicine of medicinal liquid part: Squama Manis 16.80g, Fructrs Trichosanthis 15.12g, Radix Paeoniae Alba 6.72g, Flos Carthami 6.72g, Bulbus Fritillariae Thunbergii 6.72g, Rhizoma Curcumae 13.44g, Rhizoma Corydalis 13.44g, Retinervus Luffae Fructus 13.44g, Sargassum 13.44g, Myrrha 13.44g, Rhizoma Chuanxiong 15.12g, Radix Aucklandiae 15.12g, Radix Rhapontici 8.40g, Thallus Laminariae (Thallus Eckloniae) 13.44g, Pericarpium Citri Reticulatae Viride 11.76g, Semen Vaccariae 16.80g, Fructus Liquidambaris 16.80g, trifoliate orange dash forward 11.76g, Radix Bupleuri 13.44g and Concha Arcae 13.44g.
Medicinal liquid and 75% alcoholic acid ratio are 1: 4.Clinical observation result
One, patient source: clinical
Two, treatment indication and routine number
Total patient's hentriaconta-people is divided into two groups:
(1) group: suffer from periodically distending pain of the breast or persistence distending pain of the breast, or with dysmenorrhea, menoxenia, the cycle is indefinite, emotion is impetuous, the diseases such as headache, hypochondriac pain, breast dysplasia, mastatrophy person that are in a very depressed state, pass through, but does not have outgrowth totally two ten people of mammary gland.
(2) group: suffer from cyclomastopathy person 11 people.
Three, contraindication: anemia of pregnant woman
Four, Therapeutic Method
External
Medicated cushion is put into women's medicated bra inboard, again external medicinal liquid is splashed into four meridian points on the medicated cushion on the snack made with traditional Chinese medicines, each snack made with traditional Chinese medicines and drips medicine 4-5 and drip, jede Woche drips medicine and is no less than 4 times, every auxiliary medicine pad used one month, three months is a course of treatment, uses round the clock.The prevent disease user can interim be used, and every auxiliary medicine pad is used two months, but also jede Woche dropping liquid 1-2 time of medicinal liquid.
Five, treat observing time
Be three months course of treatment two groups of patient observing times.
Six, efficacy assessment standard
1, complete: subjective symptoms or positive sign disappear.
2, produce effects: subjective symptoms or positive sign obviously alleviate or the pain time obviously shortens.
3, effective: subjective symptoms or positive sign alleviate, and perhaps the pain time shortens, and perhaps menstrual cycle other simultaneous phenomenon disappearance occurs or alleviates.
4, invalid: subjective symptoms, positive sign do not have change, and menstrual cycle occurs follows disease also not disappear or alleviate, or the pain time does not shorten.
5, side effect: occur the untoward reaction that disease increases the weight of or occur other symptom after the application.
Seven, clinical data
(1) group: among the 20 routine patients, the oldest 45 years old, reckling 18 years old; The elder of the course of disease 23 years, the shortest person 1 year; Take effect after the treatment the fastest person 8 days, elder February.
(2) group: among the 11 routine patients, suffer from cyclomastopathy ten examples, breast thing one example that swells, uterus excision person one example by health check-up of unit year or patient examination.The oldest 45 years old, reckling 33 years old average 38 years old, was all the married woman; The elder of the course of disease 10 years, the shortest person 2 years; Take effect after the treatment the fastest person January.
Eight, clinical observation curative effect
(1), first group: adopt the Chinese medicine of embodiment preparation, make medicated cushion, to no mammary gland hypertrophy and swollen thing patient clinical observation on the therapeutic effect (1) result: as table 1 and table 2 by the method described in the literary composition.
Table 1
The curative effect disease Reciprocal Complete Produce effects Effectively Invalid
Distending pain of the breast ??20 ????8 ????7 ????5 ????0
Dysmenorrhea ??17 ????5 ????5 ????7 ????0
Menoxenia ??12 ????6 ????2 ????2 ????2
Headache ??8 ????3 ????2 ????1 ????2
Emotion is impetuous gloomy ??18 ???10 ????5 ????2 ????1
Costalgia ??3 ????1 ????1 ????1
Table 2
Classification % Recovery rate Obvious effective rate Effective percentage Inefficiency Total effective rate
????40% ?35% ??25% ???0% ??100%
(2) side effect: untoward reaction all do not occur after 20 routine patients use, wherein have 3 people to use the conscious two breasts in back than plentiful before using.Plentiful rate is 15%
(3) discuss:
Periodically distending pain of the breast or persistence distending pain of the breast are numerous women's big diseases, it and chong channel are any uncomfortable, the liver and gall meridians do not relax direct relation, so other the disease of following also can appear in this disease, as dysmenorrhea, amenorrhea, menorrhagia, indefinite, headache or the like of passing through of cycle, all brought very big misery and fear for numerous women's health and soul, and do not heal the delay several years, with the passing of time very easily cause swollen thing of cyclomastopathy and breast and formation, thus harm people's health.
Above-mentioned 20 routine patients use course of treatment of this product treatment, and what have is complete, and what have alleviates in disease in varying degrees, and it not only plays the effect of independently curing the disease, and the effect that the formation of cyclomastopathy and swollen thing has been played treatment and prevented.Be not difficult to find out that from table this product is to treating this disease, the curative effect mystery, effect is remarkable, and total effective rate reaches 100%.
(2), second group: adopt the Chinese medicine of embodiment 2 preparations, make medicated cushion by described in the literary composition, to cyclomastopathy patient clinical observation on the therapeutic effect (1) result is arranged: as table 3 and table 4.
Table 3
The curative effect disease Number Complete Produce effects Effectively Invalid
Cyclomastopathy ????10 ????3 ????3 ??3 ????1
The breast thing that swells ????1
Distending pain of the breast ????11 ????3 ????3 ??3 ????2
Menalgia ????8 ????2 ????2 ??2 ????2
Menoxenia ????5 ????1 ????1 ??1 ????2
Mood disorders ????9 ????3 ????2 ??3 ????1
Headache ????1 ??1
Costalgia
Table 4
Classification % Recovery rate Obvious effective rate Effective percentage Inefficiency Total effective rate
27.3% ????27.3% ????27.2% ????18.1% ?81.8%
(2) side effect: 1 routine patient uses metanephros untoward reaction not occur, and is plentiful before the conscious two breasts of 1 example are used.
(3), two groups of treatment observation of curative effect result such as tables 5 that patient is total.
Table 5
Classification % Recovery rate Obvious effective rate Effective percentage Inefficiency Total effective rate
31 people ??35.4% ???32.2% ??26% ????6.4% ???93.6%
This product is observed by two groups of patient a course of treatment, and total effective rate reaches 93.6%.So this product not only has special effect to diseases such as distending pain of the breast, and this obstinate disease of cyclomastopathy also there is significant curative effect.Particularly long-term or interim the use also can be played positive preventive effect to the generation of breast carcinoma.

Claims (8)

1, the Chinese medicine of a kind of treatment and prevention mastopathy, this Chinese medicine comprises (percentage by weight):
(1), by the Radix Bupleuri 4-8 that pulverizes, Rhizoma Cyperi 3-16, Spica Prunellae 2-5, Pericarpium Citri Reticulatae 1-4, Pericarpium Citri Reticulatae Viride 3-7, the trifoliate orange 3-7 that dashes forward, Fructus Aurantii 1-4, Radix Aucklandiae 3-6, Rhizoma Chuanxiong 3-7, Olibanum 3-6, Radix Curcumae 3-6, Lignum Dalbergiae Odoriferae 2-6, Radix Angelicae Sinensis 3-7, rhizoma sparganic 3-6, Radix Rhapontici 3-7, BANBANGZI 3-7, Semen Vaccariae 3-7, Fructus Toosendan 2-4, Spina Gleditsiae 2-6, Thallus Laminariae (Thallus Eckloniae) 2-6, Radix Salviae Miltiorrhizae 1-3.5, Herba Leonuri 3-6, Sargassum 3-6, Fructus Liquidambaris 1.5-4, Flos Rosae Chinensis 0.5-3, Flos Rosae Rugosae 0.5-3, the component A that Concha Arcae 3-5 forms; And,
(2) comprise Squama Manis 5-10, Fructrs Trichosanthis 4-9, Radix Paeoniae Alba 1-4, Flos Carthami 1-4, Bulbus Fritillariae Thunbergii 1-4, Rhizoma Curcumae 4-8, Rhizoma Corydalis 4-8, Retinervus Luffae Fructus 4-8, Sargassum 4-8, Myrrha 4-8, Rhizoma Chuanxiong 4-9, Radix Aucklandiae 4-9, Radix Rhapontici 2-5, Thallus Laminariae (Thallus Eckloniae) 4-8, Pericarpium Citri Reticulatae Viride 2.5-7, Semen Vaccariae 4-10, Fructus Liquidambaris 4-10, the trifoliate orange 2.5-7 that dashes forward, Radix Bupleuri 4-8 and Concha Arcae 4-8 water extract and 75% ethanol are 1 with weight ratio: 1.5-1: the B component of 4 mixture.
2, Chinese medicine as claimed in claim 1, wherein, described water extract is meant that the medical material of described weight ratio decocts the medicinal liquid to obtain after the solvable composition of abundant dissolving in water.
3, Chinese medicine as claimed in claim 1, wherein, described medicinal liquid mixes with 1: 2.5 weight ratio with 75% ethanol.
4, a kind of method for preparing the Chinese medicine of treatment and prevention mastopathy comprises the steps:
(1), pulverizing weight ratio is following medical material: Radix Bupleuri 4-8, Rhizoma Cyperi 3-16, Spica Prunellae 2-5, Pericarpium Citri Reticulatae 1-4, Pericarpium Citri Reticulatae Viride 3-7, the trifoliate orange 3-7 that dashes forward, Fructus Aurantii 1-4, Radix Aucklandiae 3-6, Rhizoma Chuanxiong 3-7, Olibanum 3-6, Radix Curcumae 3-6, Lignum Dalbergiae Odoriferae 2-6, Radix Angelicae Sinensis 3-7, rhizoma sparganic 3-6, Radix Rhapontici 3-7, BANBANGZI 3-7, Semen Vaccariae 3-7, Fructus Toosendan 2-4, Spina Gleditsiae 2-6, Thallus Laminariae (Thallus Eckloniae) 2-6, Radix Salviae Miltiorrhizae 1-3.5, Herba Leonuri 3-6, Sargassum 3-6, Fructus Liquidambaris 1.5-4, Flos Rosae Chinensis 0.5-3, Flos Rosae Rugosae 0.5-3, Concha Arcae 3-5, the component A of composition;
(2) water decocts Squama Manis 5-10, Chinese juniper beach wormwood 4-9, Radix Paeoniae Alba 1-4, Flos Carthami 1-4, Bulbus Fritillariae Thunbergii 1-4, Rhizoma Curcumae 4-8, Rhizoma Corydalis 4-8, Retinervus Luffae Fructus 4-8, Sargassum 4-8, Myrrha 4-8, Rhizoma Chuanxiong 4-9, Radix Aucklandiae 4-9, Radix Rhapontici 2-5, Thallus Laminariae (Thallus Eckloniae) 4-8, Pericarpium Citri Reticulatae Viride 2.5-7, Semen Vaccariae 4-10, Fructus Liquidambaris 4-10, the trifoliate orange 2.5-7 that dashes forward, Radix Bupleuri 4-8 and Concha Arcae 4-8, fully dissolving solvable composition wherein obtains water extract; Cooling, clarification back and 75% ethanol are with 1: 1.5-1: 4 weight ratio is mixed, after leaving standstill and clarifying B component.
5, method as claimed in claim 4, wherein, described medicinal liquid mixes with 1: 2.5 weight ratio with 75% ethanol.
6, as Chinese medicine of one of claim 1 to 3 or the Chinese medicine of making as the method for claim 4 or 5, the application in the medicine of preparation treatment and prevention mastopathy.
7, application as claimed in claim 6, described mastopathy comprise periodically or persistence distending pain of the breast, breast dysplasia, mastatrophy and cyclomastopathy.
8, the medicated cushion of a kind of treatment and prevention mastopathy, comprise a cloth pad that medicated bra is cup-shaped, it is characterized in that: as the Chinese medicine of one of claim 1 to 3 or as the component A of the Chinese medicine of the method preparation of claim 4 or 5 place the interlayer of described cloth pad, described B component drip cloth pad inboard on the snack made with traditional Chinese medicines.
CN96107177A 1996-07-15 1996-07-15 Chinese drug for curing and preventing mastosis and its preparing method Expired - Fee Related CN1060664C (en)

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