CN116871125B - Full-automatic sample application production line - Google Patents

Full-automatic sample application production line Download PDF

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Publication number
CN116871125B
CN116871125B CN202311118919.6A CN202311118919A CN116871125B CN 116871125 B CN116871125 B CN 116871125B CN 202311118919 A CN202311118919 A CN 202311118919A CN 116871125 B CN116871125 B CN 116871125B
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China
Prior art keywords
sample application
conveying
along
test paper
height direction
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CN202311118919.6A
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Chinese (zh)
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CN116871125A (en
Inventor
邓庙王
何文峰
潘志业
袁达
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Guangdong Zhaoxin Intelligent Equipment Co ltd
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Guangdong Zhaoxin Intelligent Equipment Co ltd
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Priority to CN202311118919.6A priority Critical patent/CN116871125B/en
Publication of CN116871125A publication Critical patent/CN116871125A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C5/00Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work
    • B05C5/02Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work
    • B05C5/027Coating heads with several outlets, e.g. aligned transversally to the moving direction of a web to be coated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C11/00Component parts, details or accessories not specifically provided for in groups B05C1/00 - B05C9/00
    • B05C11/10Storage, supply or control of liquid or other fluent material; Recovery of excess liquid or other fluent material
    • B05C11/1036Means for supplying a selected one of a plurality of liquids or other fluent materials, or several in selected proportions, to the applying apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C13/00Means for manipulating or holding work, e.g. for separate articles
    • B05C13/02Means for manipulating or holding work, e.g. for separate articles for particular articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05CAPPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C5/00Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work
    • B05C5/02Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work
    • B05C5/0208Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work for applying liquid or other fluent material to separate articles
    • B05C5/0212Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work for applying liquid or other fluent material to separate articles only at particular parts of the articles
    • B05C5/0216Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work for applying liquid or other fluent material to separate articles only at particular parts of the articles by relative movement of article and outlet according to a predetermined path
    • B05C5/022Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work the liquid or other fluent material being discharged through an outlet orifice by pressure, e.g. from an outlet device in contact or almost in contact, with the work for applying liquid or other fluent material to separate articles only at particular parts of the articles by relative movement of article and outlet according to a predetermined path the outlet being fixed during operation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G15/00Conveyors having endless load-conveying surfaces, i.e. belts and like continuous members, to which tractive effort is transmitted by means other than endless driving elements of similar configuration
    • B65G15/22Conveyors having endless load-conveying surfaces, i.e. belts and like continuous members, to which tractive effort is transmitted by means other than endless driving elements of similar configuration comprising a series of co-operating units

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention discloses a full-automatic sample application production line, which relates to the technical field of reagent paper production, and comprises a workbench, wherein two first conveying components are arranged on the workbench at intervals along the width direction; a plurality of sample application mechanisms are sequentially arranged at intervals along the conveying path of the first conveying component, and each sample application mechanism comprises a two-axis moving component, a visual detection part and a sample application needle component; a sample application table driven by the lifting assembly is arranged right below the sample application needle assembly, and the sample application table is used for supporting test paper during sample application; the visual detection part is driven by the two-axis moving assembly to move along the length direction and the width direction and is used for shooting a pair of opposite angles of the test paper on the sample platform to obtain a first image, and the first image is transmitted to the controller; the controller compares the first image with the first standard image to obtain an offset value, corrects the moving track according to the offset value, and controls the two-axis moving assembly to move according to the corrected moving track. The invention can effectively reduce the probability of producing defective products.

Description

Full-automatic sample application production line
Technical Field
The invention relates to the technical field of reagent paper production, in particular to a full-automatic sample application production line.
Background
Reagent paper is a paper product with chemical reagent, and can judge whether an inspection target is in a certain state or not through a certain phenomenon (such as color change and the like). Common reagent paper comprises PH test paper, litmus test paper, lead acetate test paper, starch potassium iodide test paper, pregnancy test paper, cobalt chloride test paper and the like, and is widely applied to various technical fields of biology, medicine and the like due to the advantages of convenient use, reliability, low cost and the like.
In the process of manufacturing the reagent paper, the test paper needs to be spotted, namely, different types of reagents need to be covered into each square of the test paper through a spotting needle head, the same reagent is spotted in the square positioned in the same row, and different reagents are spotted in the square positioned in different rows. Along with development of science and technology, people often adopt to set up the sample application appearance on the platform that can remove in three-dimensional space and constitute automatic sample application appearance in order to improve sample application efficiency to realize the automatic sample application to test paper, in order to save labour cost. However, the existing automatic sample application instrument has high requirements on the placement accuracy of the test paper, if the placed test paper is offset, insufficient sample application or incorrect sample application position can be easily caused, and therefore the probability of producing defective products is high.
Disclosure of Invention
Therefore, the technical problem to be solved by the invention is to overcome the defects that an automatic sample application instrument for sample application of test paper has high requirement on the placement accuracy of test paper, and the sample application position cannot be automatically adjusted according to the placement condition of the test paper, so that the probability of producing defective products is high, thereby providing a full-automatic sample application production line.
According to the invention, a full-automatic sample application production line comprises:
a work table;
the two first conveying assemblies are arranged on the workbench in parallel with the length direction and are arranged at intervals along the width direction, and the two first conveying assemblies are used for supporting two side edges of test paper along the width direction;
the sample application mechanisms are sequentially arranged on the workbench at intervals along the conveying path of the first conveying assembly, and are respectively used for applying different reagents to the square grids of the corresponding row on the test paper;
each of the spotting mechanisms comprises:
a two-axis moving assembly;
the Z-axis moving assembly is arranged on the two-axis moving assembly;
the sample application needle assembly is arranged on the Z-axis moving assembly and driven by the Z-axis moving assembly to move along the height direction;
the sample application platform is positioned between the two first conveying components and is positioned right below the sample application needle component along the height direction, the sample application platform is driven by the lifting component to move along the height direction, and the sample application platform is used for supporting test paper during sample application;
The visual detection part is arranged on the two-axis moving assembly and is driven by the two-axis moving assembly to move along the length direction and the width direction; the visual detection part is used for shooting a pair of opposite angles of the test paper on the sample platform to obtain a first image, and transmitting the first image to the controller; the controller compares the first image with the first standard image to obtain an offset value, corrects the moving track according to the offset value, and controls the two-axis moving assembly to move according to the corrected moving track.
The full-automatic sample application production line has at least the following technical effects:
1. through arranging a plurality of sample application mechanisms at intervals on a workbench along a conveying path of a first conveying assembly, after the test paper to be sampled is placed between the feeding ends of the two first conveying assemblies, when the two first conveying assemblies convey the test paper to be sampled to the position right above a sample application platform, the sample application platform is controlled to lift the sample application platform, the sample application platform lifts the test paper to be sampled off the upper surface of the first conveying assembly so that a sample application needle assembly samples the reagent in a square of the test paper, then the lifting assembly is controlled to drive the sample application platform to descend, the test paper is replaced on the upper surface of the first conveying assembly so as to automatically convey the test paper to the next sample application mechanism for corresponding sample application work, and automatic sample application of the test paper is realized; meanwhile, the sample application mechanisms at different positions are respectively used for applying different reagents to the grids of the corresponding row on the test paper, so that the test paper sequentially passes through the process under the sample application needle assemblies at different positions under the conveying of the two first conveying assemblies, different reagents are respectively applied to the grids of the corresponding row on the test paper through the independent sample application mechanisms, the test paper is conveyed to the discharging end of the test paper from the feeding end of the test paper by the two first conveying assemblies, the sample application work of respectively applying different reagents to the grids of the corresponding row on the test paper can be completed at one time, the sample application efficiency is high, cross infection among different reagents can be effectively avoided in the whole sample application process, and the probability of producing defective products is reduced.
2. Through all being provided with visual detection portion on the diaxon moving assembly of every sample application mechanism, when the test paper of waiting to sample under the transport of two first transport assemblies passes through directly over one of them point sample platform, control the lifting assembly of corresponding position and start to rise corresponding sample application platform, sample application platform holds up the test paper of waiting to sample and breaks away from the upper surface of first transport assembly, then the visual detection portion of corresponding position is taken a pair of diagonal of test paper respectively under the drive of diaxon moving assembly and is obtained first image, and transmit first image to the controller, the controller compares the first image that obtains with first standard image that will take, judge whether the test paper that is held up by sample application platform produces the skew, if the placement of test paper produces the skew according to the offset value that compares first image and first standard image acquisition, and the diaxon moving assembly according to the offset value control corresponding position after the skew, thereby control sample application needle subassembly of corresponding position moves the motion corresponding line along the motion trail of the square of the test paper that produces the skew according to the actual offset, and sample application needle subassembly is not along the motion of the corresponding test paper of the square that produces the offset of corresponding square offset, and the automatic place of the test paper of the corresponding position of the test paper of control of the test paper of the accurate place of the test paper of the sample and the test paper of the sample according to be carried out, the accurate place of the test paper.
Preferably, the visual detection part is further used for shooting each square of the corresponding row of the test paper which is spotted on the spotting platform to obtain a second image, and the second image is transmitted to the controller; and the controller compares the second image with the second standard image to judge whether the sample application is qualified, and if the sample application is unqualified, the controller controls the sample application needle assembly to carry out sample application.
Preferably, a plurality of positioning columns are arranged on one side of the sample application table, which faces the discharging end of the first conveying assembly, and the positioning columns are arranged at intervals along the width direction; each positioning column is arranged parallel to the height direction, and the upper end position of the positioning column along the height direction is higher than the upper end position of the sample application table along the height direction.
Preferably, a first sensor is arranged on the workbench, and the first sensor is positioned on one side of the sample application platform, which faces the blanking end of the first conveying assembly; the first sensor is used for detecting test paper on the first conveying assembly and transmitting signals to the controller, and the controller is electrically connected with the lifting assembly.
Preferably, the two-axis moving assembly comprises a length linear driver and a width linear driver, the length linear driver is arranged on the workbench, and the length linear driver is provided with a first mounting plate moving along the length direction; the width linear driver is arranged on the first mounting plate, and is provided with a second mounting plate which moves along the width direction; the visual detection part is arranged on the second mounting plate.
Preferably, the Z-axis moving assembly includes a height linear drive disposed on the second mounting plate; the sample application needle assembly comprises a sample application needle head arranged on the height linear driver along the height direction, wherein the sample application needle head is communicated with a liquid injection pump through a material conveying conduit, and the liquid injection pump is arranged on the first mounting plate; the liquid injection pumps at different positions are respectively used for storing different reagents.
Preferably, a connecting plate is arranged at the opposite lower end of the height linear driver along the height direction, a sliding rail is arranged at the end face of one end of the connecting plate, which faces the sample application needle head, along the height direction, a lifting plate is connected to the sliding rail in a sliding manner along the height direction, and a spring is arranged between the lifting plate and the connecting plate; the sample application needle head is connected to the lifting plate.
Preferably, the feeding device further comprises a receiving mechanism, the receiving mechanism is arranged at the discharging end of the first conveying assembly, and the receiving mechanism comprises:
the two second conveying components are arranged on the workbench in parallel with the length direction and are arranged at intervals along the width direction, the distance between the two second conveying components along the width direction is smaller than the distance between the two first conveying components along the width direction, and the surface of the second conveying component, which is relatively upper along the height direction, is flush with the surface of the first conveying component, which is relatively upper along the height direction;
The two vertical plates are respectively arranged on one sides of the two second conveying assemblies, which deviate from each other in the width direction, and are arranged at the discharging end of the second conveying assemblies, the two vertical plates are symmetrically arranged in the width direction, one sides of the two vertical plates, which face each other, are respectively connected with a receiving plate in a sliding manner in the height direction, and the receiving plates are driven by a first driving mechanism to lift in the height direction; two the receiving plates are arranged at equal intervals along the height direction on one side facing each other, the receiving plates are arranged in parallel with the width direction, and the receiving plates are flush with the surface of the second conveying assembly above the second conveying assembly along the height direction, and the receiving plates are used for supporting two side edges of the test paper conveyed by the second conveying assembly along the width direction.
Preferably, a connecting rod is respectively arranged at the opposite lower ends of each receiving plate along the height direction, and a lifting seat is connected between the opposite lower end surfaces of the two connecting rods along the height direction; the first driving mechanism comprises a first main belt pulley and a first auxiliary belt pulley, the first main belt pulley is driven to rotate by a first motor, a first synchronous toothed belt is wound between the first main belt pulley and the first auxiliary belt pulley, the first synchronous toothed belt is arranged parallel to the height direction, and the lifting seat is connected to the first synchronous toothed belt.
Preferably, the feeding mechanism is arranged at the feeding end of the first conveying component, and the feeding mechanism comprises:
the two third conveying assemblies are arranged on the workbench in parallel with the length direction and are arranged at intervals along the width direction, the distance between the two third conveying assemblies along the width direction is smaller than the distance between the two first conveying assemblies along the width direction, and the surface of the third conveying assemblies, which is relatively upper along the height direction, is flush with the surface of the first conveying assemblies, which is relatively upper along the height direction;
the two vertical plates are respectively arranged on one sides of the two third conveying assemblies, which deviate from each other in the width direction, and are arranged at the feeding end of the third conveying assemblies, the two vertical plates are symmetrically arranged in the width direction, one sides of the two vertical plates, which face each other, are respectively connected with a feeding plate in a sliding manner in the height direction, and the feeding plate is driven by a second driving mechanism to lift in the height direction; two the equidistant arranging of a plurality of material bearing plates of direction of height edge of one side that the material loading board faced each other, the material bearing plate is on a parallel with width direction and arranges, is located two on the direction of height is the same the both sides limit of direction of width edge all is used for bearing test paper, and with the third conveying component is along the two of the relative top of direction of height's surface parallel and level the material bearing plate is used for carrying the test paper to the material loading end of third conveying component automatically.
Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are needed in the description of the embodiments or the prior art will be briefly described, and it is obvious that the drawings in the description below are some embodiments of the present invention, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of a fully automatic spotting line according to the present embodiment;
FIG. 2 is a schematic diagram showing the assembly of two sample application mechanisms and a material receiving mechanism in the present embodiment;
FIG. 3 is a schematic view of a portion of the structure of FIG. 2;
FIG. 4 is a schematic diagram showing an exploded structure of a part of the spotting mechanism in the present embodiment;
FIG. 5 is a schematic view showing a part of the structure of the sample needle assembled on the Z-axis moving component in the present embodiment;
fig. 6 is a schematic structural diagram of the material receiving mechanism in the present embodiment;
FIG. 7 is a schematic view of a portion of the structure of FIG. 6;
FIG. 8 is a schematic view of a portion of the structure of FIG. 6 including a first driving mechanism;
FIG. 9 is an enlarged schematic view of FIG. 8 at A;
FIG. 10 is a schematic diagram showing the assembly of two spotting mechanisms and feeding mechanisms in this embodiment.
Reference numerals illustrate:
1-a workbench, 11-a first sensor and 12-a closed working cabin;
2-a first transport assembly;
3-test paper;
41-sample stage, 411-positioning column, 42-visual detection part, 43-length linear driver, 431-first mounting plate, 44-width linear driver, 441-second mounting plate, 45-height linear driver, 451-connecting plate, 452-slide rail, 453-lifting plate, 454-spring, 455-first connecting rod, 456-second connecting rod, 461-sample needle, 462-liquid injection pump;
the device comprises a 5-receiving mechanism, a 51-second conveying assembly, a 52-vertical plate, a 53-receiving plate, a 54-receiving plate, a 55-connecting rod, a 56-lifting seat, 561-guide rails, 571-first slave pulleys, 572-first motors, 573-first synchronous toothed belts, 58-connecting seats, 581-connecting grooves, 582-connecting teeth and 59-second position sensors;
6-feeding mechanism, 61-third conveying component, 62-riser, 63-loading plate, 64-loading plate.
Detailed Description
The following description of the embodiments of the present invention will be made apparent and fully in view of the accompanying drawings, in which some, but not all embodiments of the invention are shown. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the description of the present invention, it should be noted that the directions or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present invention and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances.
In addition, the technical features of the different embodiments of the present invention described below may be combined with each other as long as they do not collide with each other.
As shown in fig. 1 to 5, the full-automatic spotting production line provided in this embodiment includes a workbench 1, two first conveying assemblies 2 arranged at intervals along a width direction are disposed on the workbench 1, and the two first conveying assemblies 2 are disposed on the workbench 1 in parallel to a length direction and are used for supporting two sides of a test paper 3 along the width direction; a plurality of sample application mechanisms are sequentially arranged on the workbench 1 at intervals along the conveying path of the first conveying component 2, the sample application mechanisms are respectively used for applying different reagents to the square grids of the corresponding row on the test paper 3, and in consideration of the fact that eleven kinds of reagents need to be applied to the square grids of ten rows of the test paper 3, the embodiment preferably comprises eleven sample application mechanisms; each sample application mechanism comprises a two-axis moving assembly and a visual detection part 42, wherein the two-axis moving assembly is arranged on the workbench 1, a Z-axis moving assembly is arranged on the two-axis moving assembly, a sample application needle assembly is arranged on the Z-axis moving assembly, and the sample application needle assembly is driven by the Z-axis moving assembly to move along the height direction and is used for applying samples of reagents in corresponding square grids of the test paper 3; a sample application table 41 is arranged right below the sample application needle assembly along the height direction, the sample application table 41 is positioned between the two first conveying assemblies 2 and driven by a lifting assembly to move along the height direction, and the sample application table 41 is used for supporting and supporting test paper 3 during sample application; the visual detection part 42 is arranged on the two-axis moving assembly and is driven by the two-axis moving assembly to move along the length direction and the width direction; the visual detection unit 42 is configured to capture a first image of a pair of opposite corners of the test paper 3 on the sample application table 41, and transmit the first image to the controller; the controller compares the first image with the first standard image to obtain an offset value, corrects the moving track according to the offset value, and controls the two-axis moving assembly to move according to the corrected moving track. It is to be understood that the height direction, width direction, and length direction described in the present embodiment refer to the height direction, width direction, and length direction shown in fig. 2.
In the full-automatic sample application production line of the embodiment, eleven sample application mechanisms are sequentially arranged on the workbench 1 at intervals along the conveying paths of the first conveying components 2, after the test paper 3 to be applied is placed between the feeding ends of the two first conveying components 2, when the two first conveying components 2 convey the test paper 3 to be applied to the position right above the sample application platform 41, the lifting component is controlled to start lifting the sample application platform 41, the sample application platform 41 lifts the test paper 3 to be applied to be separated from the upper surface of the first conveying components 2 so that the sample application needle component applies the reagent to the square of the test paper 3, then the lifting component is controlled to start lifting the sample application platform 41 to descend so as to replace the test paper 3 on the upper surface of the first conveying components 2, and the test paper 3 is automatically conveyed to the next mechanism to perform sample application work of the corresponding square, so that automatic sample application of the test paper 3 is realized; meanwhile, because the sample application mechanisms at different positions are respectively used for applying different reagents to the corresponding rows of the square boxes on the test paper 3, the test paper 3 sequentially passes through the process under the sample application needle assemblies at different positions under the conveying of the two first conveying assemblies 2, so that different reagents are respectively applied to the corresponding rows of the square boxes on the test paper 3 through the independent sample application mechanisms, the process that the two first conveying assemblies 2 convey the test paper 3 from the feeding end to the discharging end of the test paper 3 can be realized, the sample application work of respectively applying different reagents to the corresponding rows of the square boxes of the test paper 3 can be completed at one time, the sample application efficiency is high, cross infection among different reagents can be effectively avoided in the whole sample application process, and the probability of producing defective products is reduced. The visual detection parts 42 are arranged on the two-axis moving assemblies of each sample application mechanism, when the test paper 3 to be sampled passes through the position right above one of the sample application tables 41 under the conveying of the two first conveying assemblies 2, the lifting assemblies at the corresponding positions are controlled to start lifting the corresponding sample application table 41, the sample application table 41 supports the test paper 3 to be sampled and is separated from the upper surface of the first conveying assembly 2, then the visual detection parts 42 at the corresponding positions are driven by the two-axis moving assemblies to respectively shoot a pair of opposite angles of the test paper 3 to obtain a first image, the first image is transmitted to the controller, the controller compares the first image obtained by shooting with the first standard image, and judges whether the test paper 3 supported by the sample application table 41 is offset or not, if so, the test paper 3 is placed to be offset according to the offset value acquired by comparing the first image with the first standard image, and the two-axis moving assemblies at the corresponding positions are controlled to move according to the corrected moving track of the corrected sample application needle assemblies at the corresponding positions, then the corresponding positions of the sample application needle assemblies at the corresponding positions are controlled to move along the moving track corrected according to the offset value of the actually-produced test paper 3, the sample application needle 3 is accurately placed along the sample application needle 3, and the sample application needle is not accurately placed in the corresponding sample application test paper 3 is not accurately placed according to the moving track of the sample application test paper is automatically controlled, and the sample application reagent is not accurately placed along the sample application test paper is not accurately placed according to the corresponding to the moving track of the test paper. And the first image is obtained by shooting a pair of opposite angles of the test paper 3, so that the first image can be more accurately compared with the first standard image, and the offset value can be more accurately obtained.
When the test paper 3 lifted by the spotting table 41 is not shifted, the shift value is zero, that is, the movement trace does not need to be corrected.
Specifically, the first standard image is an image obtained by photographing the test paper 3 on the spot sample table 41, which is not shifted.
Specifically, the first image includes two images obtained by photographing a pair of diagonal corners of the test paper 3 on the sample stage 41, respectively.
Specifically, the visual detection section 42 is provided as a CCD camera.
Note that, the test paper 3 in which no offset is generated means that the length direction of the test paper 3 is parallel to the length direction, and the width direction of the test paper 3 is parallel to the width direction; the test paper 3 generating the offset refers to the test paper 3 generating a certain angle of rotation around the height direction relative to the test paper not generating the offset, namely, the length direction and the length direction of the test paper 3 generating the offset form a non-zero included angle, and the width direction of the test paper 3 generating the offset form a non-zero included angle; the offset value is an offset angle of the offset test paper 3 relative to the test paper 3 which does not generate offset and rotates around the height direction, that is, one square in the same row of square of the test paper 3 which does not generate offset is only required to move along the length direction (original moving track) to an adjacent square, and one square in the same row of square of the test paper 3 which generates offset is required to move along the length direction by a certain displacement amount and also required to move along the width direction by a certain displacement amount (corrected moving track); the controller corrects the movement trajectory according to the offset value based on the above-described principle.
In a specific application, the number of the spotting mechanisms may be increased or decreased reasonably according to the number of the reagents to be spotted on the test paper 3, for example, in other embodiments, the spotting mechanisms may be two, three, four, five, etc. other numbers.
Specifically, the first conveying component 2 may be a belt conveyor, so as to circularly rotate, and continuously convey the test paper 3 from the feeding end of the first conveying component 2 to the discharging end of the first conveying component 2, so as to automatically sample different reagents in corresponding squares of the test paper 3.
In some embodiments of the present invention, the visual detection unit 42 is further configured to capture a second image of each square of the corresponding row of the test paper 3 printed on the printing table 41, and transmit the second image to the controller; and the controller compares the second image with the second standard image to judge whether the sample application is qualified, and if the sample application is unqualified, the controller controls the sample application needle assembly to carry out sample application. When the test paper 3 to be spotted passes through the position right above one of the sample tables 41 under the conveying of the two first conveying components 2, is lifted and supported by the sample table 41 at the corresponding position, and is spotted by the sample needle component at the corresponding position in the square of the corresponding row, the vision detection part 42 at the position is controlled to shoot each square of the corresponding row with the spotted position in sequence to obtain a second image, the second image is transmitted to the controller, the controller compares the second image with the second standard image to judge whether the spotted position in the corresponding square is qualified, and if the spotted position is not qualified, the position coordinates of the square are marked; after each square of the corresponding row of which the sample application is completed at the position is photographed, whether the sample application is qualified or not is judged, and the position coordinates of the square with unqualified sample application are marked, the sample application needle component at the corresponding position is controlled to carry out sample application on the marked square again, and defective products caused by missing points or insufficient sample application are effectively avoided. In the whole spotting process, the spotting mechanisms at different positions carry out recheck on the spotting conditions of the squares with the corresponding row of square spotting completion in the mode, and carry out spot filling on the squares with unqualified spotting, thereby effectively reducing the probability of outputting defective products.
As shown in fig. 2, 3 and 10, in some embodiments of the present invention, the side of the spotting platform 41 facing the discharging end of the first conveying component 2 preferably has two positioning columns 411, where the two positioning columns 411 are spaced apart along the width direction; each of the positioning columns 411 is arranged parallel to the height direction, and the upper end position of the positioning column 411 in the height direction is higher than the upper end position of the spotting table 41 in the height direction. Because the upper surface of the positioning column 411 in the height direction is higher than the upper surface of the sample application table 41 in the height direction, before the test paper 3 to be sample-applied is conveyed to the position right above the sample application table 41 in the height direction, the lifting component can be controlled to drive the sample application table 41 to descend to a position (a position of a material blocking position) where the upper surface of the positioning column 411 is lower than the upper surface of the first conveying component 2, when the test paper 3 is conveyed to a position right above the sample application table 41 in the height direction, the test paper 3 is firstly abutted to the positioning column 411, then the lifting component is controlled to start to lift the sample application table 41, the sample application table 41 supports the test paper 3 to be sample-applied to a position (a position) where the sample application needle component breaks away from the upper surface of the first conveying component 2, so that the sample application needle component samples a reagent in the square of the test paper 3, and after the corresponding sample application operation is completed, the lifting component is controlled to start to drive the sample application table 41 to descend to a position (an initial position) where the upper surface of the positioning column 411 is lower than the upper surface of the first conveying component 2, the test paper 3 is automatically removed to a position where the test paper 3 is stopped, and then the lifting component is controlled to be circulated to the test paper 3; in the whole process, the positioning column 411 can prevent the test paper 3 from being conveyed out without staying above the sample application table 41, so that the probability of producing defective products is reduced, and can prevent the test paper 3 from staying at an accurate position right above the sample application table 41 due to inertia, so that the sample application quality is affected.
Specifically, the lifting assembly is configured as an electric cylinder, and the electric cylinder drives the sample application table 41 to switch among an initial position, a material blocking position and a sample application position. Of course, only one preferred configuration of the lift assembly is provided herein, and in other embodiments, the lift assembly may be configured as a double stroke cylinder.
As shown in fig. 2 and 3, in some embodiments of the present invention, the first sensor 11 is disposed on the table 1, and the first sensor 11 is located on a side of the spotting table 41 facing the discharging end of the first conveying assembly 2; the first sensor 11 is used for detecting the test paper 3 on the first conveying assembly 2 and transmitting a signal to the controller, and the controller is electrically connected with the lifting assembly. When the first sensor 11 detects that the test paper 3 is conveyed to a position right above the sample platform 41 in the height direction and is abutted against the positioning column 411, the first sensor 11 transmits a signal to the controller, the controller controls the lifting assembly to start to drive the sample platform 41 to lift the test paper 3 to be sampled to a position separated from the upper surface of the first conveying assembly 2, namely, the position is switched from the sample blocking position to the sample sampling position, so that the test paper 3 is ensured to stay at an accurate position right above the sample platform 41 and is lifted for sample sampling, and the sample sampling quality is improved.
As shown in fig. 2 to 4, in some embodiments of the present invention, the two-axis moving assembly includes a length linear driver 43 and a width linear driver 44, the length linear driver 43 is disposed on the table 1, and the length linear driver 43 is provided with a first mounting plate 431 moving in a length direction; the width linear driver 44 is provided on the first mounting plate 431, and the width linear driver 44 is provided with a second mounting plate 441 that moves in the width direction; the visual inspection unit 42 is provided on the second mounting plate 441. In the process of shooting a pair of diagonal corners of the test paper 3 supported and supported by the sample application table 41 to obtain a first image, the visual detection part 42 can be driven to move along the length direction and the width direction by the length linear driver 43 and the width linear driver 44, namely, the visual detection part 42 can be driven to move at any position of the upper surface of the sample application table 41 along the height direction, so that the first image can be accurately shot to obtain, whether the placement of the test paper 3 is offset or not can be accurately judged, an offset value can be accurately obtained, a moving track can be corrected better according to the obtained offset value, and the sample application needle assembly at the corresponding position can be controlled to move and sample according to the corrected moving track, so that the corresponding reagent can be accurately sampled in the square at the corresponding position of the test paper 3, and the probability of producing defective products can be effectively reduced. Specifically, the length linear driver 43 is configured as an electric cylinder or an air cylinder or a linear motor, and drives the first mounting plate 431 to reciprocate in the length direction; the width linear driver 44 is provided as an electric cylinder or an air cylinder or a linear motor, and drives the second mounting plate 441 to reciprocate in the width direction.
As shown in fig. 2-5, in some embodiments of the invention, the Z-axis moving assembly includes a height linear actuator 45 disposed on the second mounting plate 441; the sample application needle assembly comprises a sample application needle head 461 arranged on the height linear driver 45 along the height direction, the sample application needle head 461 is communicated with a liquid injection pump 462 through a material conveying conduit, and the liquid injection pump 462 is arranged on the first mounting plate 431; the infusion pumps 462 located at different locations are each used to hold different reagents. The sample application needle 461 can move in the left-right, front-back and up-down three dimensions under the drive of the length linear driver 43, the width linear driver 44 and the height linear driver 45, so that the sample application needle 461 can sample and withdraw at any position on the upper surface of the test paper 3 supported by the sample application table 41, the use functionality is improved, the production efficiency is improved, and the automation level of the sample application production line of the embodiment is further improved; simultaneously, each liquid injection pump 462 is respectively arranged on the first mounting plate 431 of the corresponding sample application mechanism, so that the relative distance between each liquid injection pump 462 and the corresponding sample application needle 461 is reduced, the liquid is better supplied to the sample application needle 461, and compared with the liquid injection pump 462 arranged on the second mounting plate 441, the liquid injection pump 462 is more stable in the sample application process because the first mounting plate 431 is directly arranged on the workbench 1 through the length linear driver 43, and the sample application quality is further improved. Specifically, the elevation linear actuator 45 is provided as an electric cylinder or an air cylinder or a linear motor, and drives the spotting needle 461 to reciprocate in the elevation direction.
As shown in fig. 5, in some embodiments of the present invention, a connection plate 451 is disposed at an opposite lower end of the height linear driver 45 in the height direction, a sliding rail 452 is disposed on the connection plate 451 in the height direction toward an end surface of the spotting needle 461, a lifting plate 453 is slidably connected on the sliding rail 452 in the height direction, and a spring 454 is disposed between the lifting plate 453 and the connection plate 451; the sample needle 461 is attached to the lifting plate 453. Considering that the distance between the sample needle 461 and the test paper 3 is small when the sample needle 461 samples in the square on the upper surface of the test paper 3 lifted by the sample platform 41, if the thickness of one batch of test paper 3 is large, in order to avoid hard contact with the test paper 3 in the process of dropping the sample needle 461 in the height direction to cause damage to the sample needle 461, in this embodiment, the sample needle 461 is slidingly connected to the connecting plate 451 in the height direction by the lifting plate 453, and a spring 454 is arranged between the lifting plate 453 and the connecting plate 451, and relative to fixing the sample needle 461 to the connecting plate 451, the sample needle 461 does not generate impact force between the sample needle 461 and the test paper 3 due to movement in the height direction when the sample needle 461 contacts with the test paper 3, and the hard contact between the sample needle 461 and the test paper 3 easily damages the sample needle 461; in this embodiment, when the sample application needle 461 gradually descends to contact with the test paper 3, the sample application needle 461 and the lifting plate 453 are subjected to upward reaction force, so that the spring 454 can be stretched to deform and move upwards against the elastic force of the spring 454, so that the sample application needle 461 moves upwards along with the lifting plate 453, the impact force generated when the sample application needle 461 contacts with the test paper 3 is relieved through the deformation of the spring 454, and the impact damage phenomenon of the sample application needle 461 is reduced; can adapt to the sample application of test paper 3 with different thickness, and has wide application range.
As shown in fig. 5, specifically, a side of the lifting plate 453 toward the connection plate 451 is provided with a first connection rod 455, the first connection rod 455 is arranged parallel to the width direction, and a suspension end of the first connection rod 455 is provided with a first annular groove; the connecting plate 451 is provided with the second connecting rod 456 towards one side of the first connecting rod 455, the second connecting rod 456 is arranged along the length direction, and is located the below of the first connecting rod 455 along the height direction, the suspended end of the second connecting rod 456 is provided with the second annular groove, one end of the spring 454 is provided in the first annular groove, and the other end is provided in the second annular groove.
As shown in fig. 1, 2 and 6 to 8, in some embodiments of the present invention, the full-automatic spotting line further includes a material receiving mechanism 5, where the material receiving mechanism 5 is disposed at a material discharging end of the first conveying component 2, the material receiving mechanism 5 includes two second conveying components 51 that are arranged on the workbench 1 at intervals along a width direction, the two second conveying components 51 are arranged on the workbench 1 in parallel with a length direction, a distance between the two second conveying components 51 along the width direction is smaller than a distance between the two first conveying components 2 along the width direction, and a surface of the second conveying component 51 relatively above along a height direction is level with a surface of the first conveying component 2 relatively above along the height direction; one vertical plate 52 is respectively arranged at one side of the two second conveying assemblies 51, which are away from each other in the width direction, and the two vertical plates 52 are arranged at the blanking end of the second conveying assemblies 51; the two vertical plates 52 are symmetrically arranged along the width direction, one sides of the two vertical plates 52 facing each other are connected with a material receiving plate 53 in a sliding manner along the height direction, and the material receiving plate 53 is driven by a first driving mechanism to lift along the height direction; eight receiving plates 54 are preferably arranged at equal intervals in the height direction on the sides of the two receiving plates 53 facing each other, the receiving plates 54 are arranged parallel to the width direction, and the two receiving plates 54 which are flush with the surface of the second conveying assembly 51 facing upward in the height direction are used for supporting the two sides of the test paper 3 conveyed by the second conveying assembly 51 in the width direction. Through the interval that is less than two first conveying component 2 along width direction that sets up the interval along width direction with two second conveying component 51 for after the test paper 3 that the sample application was accomplished gets into the material loading end of second conveying component 51 from the unloading end of first conveying component 2, two second conveying component 51 support the position that the both sides limit of test paper 3 along width direction was partial to test paper 3 center, ensure that two second conveying component 51 carry the test paper 3 that the sample application was accomplished to the unloading end of second conveying component 51, the both sides limit of test paper 3 that the sample application was accomplished along width direction is respectively by two adapting plate 54 bearing of the relative top of second conveying component 51 along the direction of height, then control first actuating mechanism drive two adapting plate 53 upwards move simultaneously, until being located the position of adapting plate 54 below the supporting with test paper 3 and adapting plate 54 relatively top along the direction of height, repeat above-mentioned action, realize the automatic unloading collection temporary storage of test paper 3 that the sample application was accomplished, and after setting up to collect the ration (eight and take out the automatic level test paper down again, further improvement horizontal input is carried out by the automation.
In a specific application, the number of receiving plates 54 of each receiving plate 53 that are spaced apart along the height direction is reasonably increased or decreased according to the size of the receiving plate 53 and the thickness of the test paper 3, for example, in other embodiments, seven, nine, ten, eleven, etc. receiving plates 54 of each receiving plate 53 are spaced apart along the height direction.
Specifically, the second conveying assembly 51 may be a belt conveyor, so as to rotate circularly, and continuously convey the spotted test paper 3 automatically from the discharging end of the first conveying assembly 2 to the receiving mechanism 5 for collecting and temporarily storing.
As shown in fig. 6 to 8, in some embodiments of the present invention, each of the opposite lower ends of the receiving plates 53 in the height direction is provided with a connecting rod 55, the connecting rods 55 are arranged in the height direction, and a lifting seat 56 is connected between the opposite lower end surfaces of the two connecting rods 55 in the height direction; the first driving mechanism includes a first primary pulley and a first secondary pulley 571, the first primary pulley is driven to rotate by a first motor 572, a first synchronous toothed belt 573 is wound between the first primary pulley and the first secondary pulley 571, the first synchronous toothed belt 573 is arranged parallel to the height direction, and the lifting seat 56 is connected to the first synchronous toothed belt 573. Because the lower end surfaces of the two connecting rods 55 along the height direction are connected through the lifting seat 56, after two of the bearing plates 54 positioned on the same straight line in the height direction bear one test paper 3 after finishing sample application, the first motor 572 is started to drive the first main belt pulley to rotate forward, so that the first synchronous toothed belt 573 rotates forward to drive the lifting seat 56 to lift the distance between two adjacent bearing plates 54 positioned on the same receiving plate 53 along the height direction, and further drive the two adjacent bearing plates 54 positioned below the bearing plate 54 bearing the test paper 3 to synchronously lift to the position flush with the surface of the second conveying assembly 51 relatively above along the height direction, so as to bear, collect and temporarily store the test paper 3 finished by the next sample application.
As shown in fig. 8 and 9, in some embodiments of the present invention, the lifting base 56 is connected to the first synchronous toothed belt 573 through a connecting base 58, a connecting slot 581 is formed in the connecting base 58 in a penetrating manner in a height direction, the connecting slot 581 is used for the first synchronous toothed belt 573 to pass through, a connecting tooth 582 is disposed on a side of the connecting slot 581 facing to an inner tooth shape of the first synchronous toothed belt 573, and the connecting tooth 582 is meshed with the inner tooth shape of the first synchronous toothed belt 573. Through the internal tooth shape meshing of the connecting teeth 582 and the first synchronous toothed belt 573, the friction force between the connecting seat 58 and the first synchronous toothed belt 573 is increased, so that the slipping of the connecting seat 58 relative to the first synchronous toothed belt 573 can be effectively avoided, the two receiving plates 53 are driven to rise a set value along the height direction at the same time, and the continuous collection and temporary storage of test paper finished products with set quantity are ensured.
In order to improve the smooth and straight lifting of the lifting seat 56 along the height direction under the driving of the first synchronous toothed belt 573, so as to improve the temporary storage work of the test paper 3 after the sample is collected, as shown in fig. 6 and 8, specifically, the material receiving mechanism 5 further includes a guide rail 561 disposed on the workbench 1 along the height direction, the guide rail 561 is located under the opposite side of the material receiving plate 53 along the height direction, and the lifting seat 56 is slidably connected to the guide rail 561.
As shown in fig. 7, in some embodiments of the present invention, a second position sensor 59 is disposed below the receiving plate 53 in the height direction, and the second position sensor 59 is located between the two second conveying assemblies 51 and is located at the discharging end of the second conveying assembly 51; the second position sensor 59 is configured to detect the test paper 3 on the discharging end of the second conveying assembly 51, and transmit a signal to the controller, where the controller is electrically connected to the first driving mechanism. When the test paper 3 with the spotted sample is conveyed to the discharging end of the second conveying component 51 and is supported by the two bearing plates 54 which are flush with the surface of the second conveying component 51 above the second conveying component in the height direction, the second position sensor 59 is triggered, the second position sensor 59 transmits a signal to the controller, and the controller controls the first driving mechanism to start driving the two bearing plates 53 to rise a set value in the height direction at the same time, so that continuous collection and temporary storage of a set amount of test paper finished products are ensured.
As shown in fig. 1 and 10, in some embodiments of the present invention, the full-automatic spotting production line further includes a feeding mechanism 6, where the feeding mechanism 6 is disposed at a feeding end of the first conveying component 2, the feeding mechanism 6 includes two third conveying components 61 that are arranged on the workbench 1 at intervals in a width direction, the two third conveying components 61 are arranged parallel to a length direction, a distance between the two third conveying components 61 in the width direction is smaller than a distance between the two first conveying components 2 in the width direction, and a surface of the third conveying component 61 that is relatively upper in a height direction is flush with a surface of the first conveying component 2 that is relatively upper in the height direction; one side, away from each other in the width direction, of the two third conveying assemblies 61 is respectively provided with a vertical plate 62, the two vertical plates 62 are arranged at the feeding end of the third conveying assembly 61 and are symmetrically arranged in the width direction, one sides, facing each other, of the two vertical plates 62 are respectively connected with a feeding plate 63 in a sliding manner in the height direction, and the feeding plates 63 are driven by a second driving mechanism to lift in the height direction; eight material bearing plates 64 are preferably arranged at equal intervals along the height direction on one side of the two material bearing plates 63 facing each other, the material bearing plates 64 are arranged parallel to the width direction, the two material bearing plates 64 positioned on the same straight line of the height direction are used for bearing two side edges of the test paper 3 along the width direction, and the two material bearing plates 64 flush with the surface of the third conveying assembly 61 above the opposite direction along the height direction are used for automatically conveying the test paper 3 to the material loading end of the third conveying assembly 61. Through being less than the interval of two first conveying components 2 along width direction with the interval setting of two third conveying components 61 along width direction for when starting third conveying components 61, can be with the automatic output of test paper 3 that waits to sample between two loading plates 64 of third conveying components 61 upper surface parallel and level, and carry the feed end of second conveying components 51 and the test paper that waits to sample is held by two first conveying components 2 respectively along width direction's both sides limit, control second actuating mechanism and drive two loading plates 63 and move the interval along the height direction of adjacent two loading plates 64 simultaneously, make to hold two loading plates 64 that wait to sample test paper 3 and lie in the same straight line of height direction decline to the position with third conveying components 61 upper surface parallel and level, repeat above-mentioned action, realize with setting up the automatic continuous transport of test paper 3 that waits to sample of quantitative (eight) in first conveying components 2, further improve automatic level.
In a specific application, the number of the loading plates 64 arranged at intervals along the height direction of each loading plate 63 is reasonably increased or decreased according to the size of the loading plate 63 and the thickness of the test paper 3, for example, in other embodiments, seven, nine, ten, eleven and other numbers of loading plates 64 are arranged on each loading plate 63 at intervals along the height direction.
Specifically, the third conveying component 61 may be a belt conveyor, so as to rotate circularly, and continuously and automatically convey the test paper 3 to be spotted to the feeding end of the first conveying component 2.
In some embodiments of the present invention, the opposite lower ends of the feeding plate 63 along the height direction are respectively provided with a connecting column, and a lifting block is connected between the opposite lower end surfaces of the two connecting columns along the height direction; the second driving mechanism comprises a second main belt pulley and a second auxiliary belt pulley, the second main belt pulley is driven to rotate by a second motor, a second synchronous toothed belt is wound between the second main belt pulley and the second auxiliary belt pulley, the second synchronous toothed belt is arranged parallel to the height direction, and the lifting block is connected with the second synchronous toothed belt. Because the lower end surfaces of the two connecting columns along the height direction are connected through the lifting block, when the third conveying assembly 61 automatically outputs the test paper 3 to be spotted, which is positioned between the two material bearing plates 64 flush with the upper surface of the third conveying assembly 61, the second motor is started to drive the second main belt pulley to rotate forward, so that the second synchronous toothed belt rotates forward to drive the lifting block to descend the distance between the two adjacent material bearing plates 64 positioned on the same material bearing plate 63 along the height direction, and the two material bearing plates 64 which bear the test paper 3 to be spotted and are positioned on the same straight line along the height direction descend to the position flush with the upper surface of the third conveying assembly 61, thereby realizing automatic continuous conveying of the set quantity (eight) of test papers 3 to be spotted into the first conveying assembly 2, and further improving the automation level.
In some embodiments of the present invention, the lifting block is connected with the second synchronous toothed belt through a mounting seat, a mounting through groove is formed in the mounting seat in a penetrating manner along the height direction, the mounting through groove is used for the second synchronous toothed belt to pass through, a mounting tooth is arranged on one side, facing the inner tooth shape of the second synchronous toothed belt, of the mounting through groove, and the mounting tooth is meshed with the inner tooth shape of the second synchronous toothed belt. Through the internal tooth form meshing of installation tooth and second synchronous toothed belt, increase the frictional force between mount pad and the second synchronous toothed belt, can effectually avoid the mount pad to produce the slip relative to the synchronous toothed belt of second, ensure to drive two loading plates 63 and descend the settlement numerical value along the direction of height simultaneously, ensure to carry the continuous automatic of the test paper 3 of setting quantity to first conveying assembly 2.
In some embodiments of the present invention, a third position sensor is disposed below the material bearing plate 64 in the height direction, and the third position sensor is located between the two third conveying assemblies 61 and is located at the material loading end of the third conveying assemblies 61; the third position sensor is used for detecting the test paper 3 on the feeding end of the third conveying assembly 61 and transmitting a signal to the controller, and the controller is electrically connected with the second driving mechanism. When the test paper 3 to be spotted, which is positioned on the two loading plates 64 flush with the upper surface of the third conveying assembly 61, is automatically conveyed to the loading end of the first conveying assembly 2 by the third conveying assembly 61, the third position sensor is triggered, the third position sensor transmits a signal to the controller, and the controller controls the second driving mechanism to start to drive the two loading plates 63 to simultaneously descend by a set value along the height direction, so that the continuous and automatic conveying of the set amount of test paper 3 to the first conveying assembly 2 is ensured.
The feeding mechanism 6 and the receiving mechanism 5 have the same composition and structure, and the difference is that the order of controlling the movement is different.
As shown in fig. 1, specifically, the workbench 1 is further provided with sealed working chambers 12 with the same number as the spotting mechanisms, one end of the sealed working chamber 12 is provided with a feed inlet, and the other end is provided with a discharge outlet; the first transport assembly 2, the spotting mechanism are both located in the closed working chamber 12.
It is apparent that the above examples are given by way of illustration only and are not limiting of the embodiments. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. While still being apparent from variations or modifications that may be made by those skilled in the art are within the scope of the invention.

Claims (9)

1. A full-automatic spotting production line, comprising:
a work table (1);
the two first conveying assemblies (2) are arranged on the workbench (1) in parallel with the length direction and are arranged at intervals along the width direction, and the two first conveying assemblies (2) are used for supporting two side edges of the test paper (3) along the width direction;
The sample application mechanisms are sequentially arranged on the workbench (1) at intervals along the conveying path of the first conveying component (2), and are respectively used for applying different reagents to the square grids of the corresponding row on the test paper (3);
each of the spotting mechanisms comprises:
a two-axis moving assembly;
the Z-axis moving assembly is arranged on the two-axis moving assembly;
the sample application needle assembly is arranged on the Z-axis moving assembly and driven by the Z-axis moving assembly to move along the height direction;
the sample application platform (41) is positioned between the two first conveying components (2) and is positioned right below the sample application needle component along the height direction, the sample application platform (41) is driven by the lifting component to move along the height direction, and the sample application platform (41) is used for supporting the test paper (3) during sample application;
a visual detection unit (42) which is provided on the two-axis movement unit and is driven by the two-axis movement unit to move in the longitudinal direction and the width direction; the visual detection part (42) is used for shooting a pair of opposite angles of the test paper (3) on the sample application table (41) to obtain a first image, and transmitting the first image to the controller; the controller compares the first image with a first standard image to obtain an offset value, corrects a moving track according to the offset value, and controls the two-axis moving assembly to move according to the corrected moving track;
Still include receiving mechanism (5), receiving mechanism (5) set up the unloading end of first conveying component (2), receiving mechanism (5) include:
the two second conveying assemblies (51) are arranged on the workbench (1) in parallel with the length direction and are arranged at intervals along the width direction, the distance between the two second conveying assemblies (51) along the width direction is smaller than the distance between the two first conveying assemblies (2) along the width direction, and the surface of the second conveying assemblies (51) relatively above along the height direction is level with the surface of the first conveying assemblies (2) relatively above along the height direction;
the two vertical plates (52) are respectively arranged on one sides of the two second conveying assemblies (51) which deviate from each other in the width direction and are arranged at the blanking end of the second conveying assemblies (51), the two vertical plates (52) are symmetrically arranged in the width direction, one sides of the two vertical plates (52) which face each other are connected with a receiving plate (53) in a sliding manner in the height direction, and the receiving plate (53) is driven by a first driving mechanism to lift in the height direction; a plurality of bearing plates (54) are arranged on one side, facing each other, of the two receiving plates (53) at equal intervals along the height direction, the bearing plates (54) are arranged parallel to the width direction, and the two bearing plates (54) which are flush with the surface, above the second conveying assembly (51), of the second conveying assembly (51) along the height direction are used for bearing two side edges, along the width direction, of the test paper (3) conveyed by the second conveying assembly (51).
2. A fully automatic spotting line according to claim 1, characterized in that the vision detection section (42) is further configured to take a second image of each square of the corresponding row of spotted test strips (3) on the spotting table (41), and transmit the second image to the controller; and the controller compares the second image with the second standard image to judge whether the sample application is qualified, and if the sample application is unqualified, the controller controls the sample application needle assembly to carry out sample application.
3. The full-automatic spotting production line according to claim 1, characterized in that one side of the spotting table (41) facing the discharging end of the first conveying component (2) is provided with a plurality of positioning columns (411), and the positioning columns (411) are arranged at intervals along the width direction; each positioning column (411) is arranged parallel to the height direction, and the upper end position of the positioning column (411) along the height direction is higher than the upper end position of the sample application table (41) along the height direction.
4. A fully automatic spotting line according to claim 1, characterized in that the table (1) is provided with a first sensor (11), the first sensor (11) being located on the side of the spotting table (41) facing the blanking end of the first transport assembly (2); the first sensor (11) is used for detecting test paper (3) on the first conveying assembly (2) and transmitting signals to the controller, and the controller is electrically connected with the lifting assembly.
5. A fully automated spotting line according to claim 1, characterized in that the two-axis movement assembly comprises a length linear drive (43) and a width linear drive (44), the length linear drive (43) being arranged on the table (1), the length linear drive (43) being provided with a first mounting plate (431) moving in the length direction; the width linear driver (44) is provided on the first mounting plate (431), and the width linear driver (44) is provided with a second mounting plate (441) that moves in the width direction; the visual detection unit (42) is provided on the second mounting plate (441).
6. A fully automated spotting line according to claim 5, characterized in that the Z-axis movement assembly comprises a height linear drive (45) provided on the second mounting plate (441); the sample application needle assembly comprises a sample application needle head (461) arranged on the height linear driver (45) along the height direction, the sample application needle head (461) is communicated with a liquid injection pump (462) through a material conveying conduit, and the liquid injection pump (462) is arranged on the first mounting plate (431); the infusion pumps (462) are located at different positions for respectively storing different reagents.
7. The full-automatic spotting production line according to claim 6, wherein a connecting plate (451) is arranged at the opposite lower end of the height linear driver (45) along the height direction, a sliding rail (452) is arranged at the end face of the connecting plate (451) towards one end of the spotting needle head (461) along the height direction, a lifting plate (453) is slidingly connected on the sliding rail (452) along the height direction, and a spring (454) is arranged between the lifting plate (453) and the connecting plate (451); the sample application needle head (461) is connected to the lifting plate (453).
8. The full-automatic spotting production line according to claim 1, wherein a connecting rod (55) is respectively arranged at the opposite lower ends of each material receiving plate (53) along the height direction, and a lifting seat (56) is connected between the opposite lower end surfaces of the two connecting rods (55) along the height direction; the first driving mechanism comprises a first main belt pulley and a first auxiliary belt pulley (571), the first main belt pulley is driven to rotate by a first motor (572), a first synchronous toothed belt (573) is wound between the first main belt pulley and the first auxiliary belt pulley (571), the first synchronous toothed belt (573) is arranged parallel to the height direction, and the lifting seat (56) is connected to the first synchronous toothed belt (573).
9. A fully automatic spotting line according to any one of claims 1 to 7, characterized in that it further comprises a feeding mechanism (6), said feeding mechanism (6) being arranged at the feeding end of said first transport assembly (2), said feeding mechanism (6) comprising:
two third conveying components (61) which are parallel to the length direction and are arranged on the workbench (1) at intervals along the width direction, wherein the distance between the two third conveying components (61) along the width direction is smaller than the distance between the two first conveying components (2) along the width direction, and the surface of the third conveying components (61) which is relatively upper along the height direction is level with the surface of the first conveying components (2) which is relatively upper along the height direction;
the two vertical plates (62) are respectively arranged on one sides of the two third conveying assemblies (61) which deviate from each other in the width direction and are arranged at the feeding end of the third conveying assemblies (61), the two vertical plates (62) are symmetrically arranged in the width direction, one sides of the two vertical plates (62) which face each other are respectively connected with a feeding plate (63) in a sliding manner in the height direction, and the feeding plates (63) are driven by a second driving mechanism to lift in the height direction; two the equidistant arranging of a plurality of material bearing plates (64) of direction of height is followed to one side that loading plate (63) faced each other, material bearing plate (64) are on a parallel with width direction and are arranged, are located two on the same straight line of direction of height material bearing plate (64) all are used for bearing test paper (3) along the both sides limit of width direction, and with two of the relative top of direction of height surface parallel and level of third conveying component (61) material bearing plate (64) are used for carrying test paper (3) to the material loading end of third conveying component (61).
CN202311118919.6A 2023-09-01 2023-09-01 Full-automatic sample application production line Active CN116871125B (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109290088A (en) * 2018-08-08 2019-02-01 湖南晗光智能科技股份有限公司 A kind of spraying intelligence control system and automation equipment based on machine vision
CN215393195U (en) * 2021-05-24 2022-01-04 武汉欧双光电科技股份有限公司 Automatic laser marking machine
CN215866743U (en) * 2021-05-14 2022-02-18 广东凯普生物科技股份有限公司 Series full-automatic sample point appearance
CN215866742U (en) * 2021-05-14 2022-02-18 广东凯普生物科技股份有限公司 Full-automatic sample point appearance
CN115365088A (en) * 2022-09-05 2022-11-22 苏州光宝科技股份有限公司 Dispensing method and device based on visual guidance

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109290088A (en) * 2018-08-08 2019-02-01 湖南晗光智能科技股份有限公司 A kind of spraying intelligence control system and automation equipment based on machine vision
CN215866743U (en) * 2021-05-14 2022-02-18 广东凯普生物科技股份有限公司 Series full-automatic sample point appearance
CN215866742U (en) * 2021-05-14 2022-02-18 广东凯普生物科技股份有限公司 Full-automatic sample point appearance
CN215393195U (en) * 2021-05-24 2022-01-04 武汉欧双光电科技股份有限公司 Automatic laser marking machine
CN115365088A (en) * 2022-09-05 2022-11-22 苏州光宝科技股份有限公司 Dispensing method and device based on visual guidance

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