CN116850255A - Traditional Chinese medicine foot bath composition for treating dysmenorrhea and preparation method thereof - Google Patents
Traditional Chinese medicine foot bath composition for treating dysmenorrhea and preparation method thereof Download PDFInfo
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- CN116850255A CN116850255A CN202311060085.8A CN202311060085A CN116850255A CN 116850255 A CN116850255 A CN 116850255A CN 202311060085 A CN202311060085 A CN 202311060085A CN 116850255 A CN116850255 A CN 116850255A
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- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses a traditional Chinese medicine foot bath composition for treating dysmenorrhea and a preparation method thereof. The method comprises weighing the raw materials to obtain Chinese medicinal mixture, sterilizing at gradient temperature, packaging to obtain medicinal powder bag, and decocting the medicinal powder bag and water or soaking the medicinal powder bag and boiling water to obtain the Chinese medicinal foot bath liquid. By combining the pathogenesis characteristics of dysmenorrhea, the medicine is selected in a targeted way, the cause is checked, the disease is treated, the root is solved, and the treatment is based on syndrome differentiation. The medicines are combined to produce synergistic effect, and the curative effect and the treatment effect of the medicines are improved.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine foot bath composition for treating dysmenorrhea and a preparation method thereof.
Background
Dysmenorrhea refers to the occurrence of cyclic cramping pain in the lower abdomen before and after menstruation or during menstruation in women, accompanied by soreness of the waist or other uncomfortable symptoms, and is divided into primary and secondary. In recent years, the incidence of endometriosis has increased significantly, and endometriosis also causes dysmenorrhea and chronic pelvic pain. Dysmenorrhea is always a common disease which afflicts women's life, and the prevalence rate is generally 45% -95%. The traditional Chinese and western medicine are different in terms of dysmenorrhea treatment. Western medicine considers that dysmenorrhea is caused by uterine smooth muscle spasm, uterine ischemia and anoxia, etc. caused by hormone imbalance, etc., and hormone medicines, nonsteroidal anti-inflammatory medicines and antipyretic analgesic medicines are often selected for treatment, so that the medicine effect can be rapidly exerted. However, non-steroidal anti-inflammatory drugs can induce gastrointestinal diseases in patients, and hormonal drugs can affect the normal fertility function of females, and researches report that oral contraceptives can relieve pain, but can cause irregular menstruation and even stop menstruation after long-term administration. Therefore, the western medicine treatment method has quick response, but treats both symptoms and root causes, and has larger adverse reaction.
According to traditional Chinese medicine, the pathogenesis of dysmenorrhea is caused by unsmooth qi and blood circulation, blocked uterine blood flow or malnutrition of uterine organs, and pain is caused by obstruction, wherein cold-dampness stagnation is common in uterine qi and blood. The treatment should be mainly to warm channel, dispel cold, dispel dampness, activate blood, remove stasis and relieve pain. The traditional Chinese medicine method for clinically treating dysmenorrhea mainly comprises an internal treatment method of traditional Chinese medicine (comprising a traditional Chinese medicine compound, a Chinese patent medicine and the like) and an external treatment method of traditional Chinese medicine (comprising acupuncture, a traditional Chinese medicine retention enema method, moxibustion, acupoint external application, massage therapy, auricular points and the like). The traditional Chinese medicine has wide development prospect for treating dysmenorrhea, in particular to the clinical application of the capsule for removing blood stasis of lower abdomen and eight delicacies and motherwort pills in the aspects of research and development of new traditional Chinese medicine preparations. However, the oral administration of the traditional Chinese medicine is too much or too short, which causes the destruction of the effective components and the un-decoction, and the traditional Chinese medicine decoction is difficult to carry and is not suitable for long-term storage. The oral traditional Chinese medicine preparation often affects the digestive system, urinary system, blood system and respiratory system, wherein the digestive system damage incidence is highest, and the reasons such as taste of the traditional Chinese medicine affect the sensitivity, tolerance and compliance of patients to the medicine, so that the curative effect is weakened and reduced. The external treatment method of traditional Chinese medicine has various treatment methods, high safety, small adverse reaction, low price and easy acceptance by patients, can avoid adverse reactions such as drug dependence and drug resistance, and has unique advantages and definite curative effect. However, different problems have been presented to affect the popularization and application. Needling is a common external treatment method for treating dysmenorrhea, and by selecting an empirical effect point for treating dysmenorrhea, taking the point based on syndrome differentiation and applying a method of reinforcing deficiency and purging excess, the qi and blood of the uterus of thoroughfare and conception vessels can be regulated, so that the aim of treating dysmenorrhea is fulfilled, and the traditional Chinese medicine composition has the advantages of quick response and high curative effect. However, needling at present has certain traumata and requires certain expertise to support and select acupoints, which is not suitable for patients to operate by themselves. The moxibustion has very remarkable curative effect in the process of treating dysmenorrhea because the warm effect of the moxibustion directly penetrates through the acupoints to the inside of the body, but the moxibustion materials are different, the heat generating substances are different, the human body reactions are also different, the moxibustion needs to ensure proper temperature and treatment duration, a patient needs to take a certain position or special equipment, the moxibustion needs to be treated by other people, and in addition, the excessive temperature can cause scalds and scars, which is harmful to the beauty. The traditional Chinese medicine foot bath is a special health care therapy for external treatment of traditional Chinese medicine, and has been developed rapidly in recent years. According to the principle of dialectical treatment of traditional Chinese medicine, theory of visceral manifestation, theory of meridian conduction and theory of modern foot reflex zone, proper Chinese herbal medicines are selected and decocted into traditional Chinese medicine hot water, and the traditional Chinese medicine hot water is used for soaking and washing feet to dredge the meridians of the feet, so that the foot reflex zone is stimulated benign, and the pharmacological effect of the whole organism and the pharmacological effect of the part of the focus caused by the absorption of Chinese herbal medicine ions through the mucous membrane, acupoints and reflex zone on the skin surface of the foot are obtained, thereby ensuring smooth qi and blood running of each tissue organ and part of the organism, and having the health care effects of improving physique and preventing disease recurrence. The traditional Chinese medicine foot bath achieves the aim of treating dysmenorrhea through dual actions of heat and medicines. The traditional Chinese medicine considers that heat is relaxed to relax the muscles and tendons, heat is relaxed to promote blood circulation, heat energy is used for dredging channels and collaterals, relieving spasm, opening striae and dispelling cold evil; the medicine has effects of regulating viscera function, harmonizing qi and blood, and removing diseases. The traditional Chinese medicine foot bath prescription is convenient to take, does not need special equipment or the assistance of other people, does not increase the burden of the gastrointestinal tract, influences the liver and kidney functions, and has higher tolerance and acceptance of patients. The foot bath formula is based on the reasonable formula of the disease mechanism key of 'three reasons' and combines the regional characteristics of Gansu northwest high cold and the onset characteristics of female dysmenorrheal caused by cold-dampness, so as to achieve the purposes of dispelling the cold-dampness, regulating the qi and blood of chong and ren cells and treating dysmenorrheal, and aims at treating the disease and solving the root cause. The prescription has reasonable dosage, can exert the drug effect to the maximum extent, and has definite clinical curative effect through multiple clinical trials. In addition, the selected medicinal materials are mostly produced in Gansu province, and more large amounts of genuine medicinal materials such as angelica sinensis, rheum officinale, notopterygium root and the like are provided, so that on one hand, the quality of the genuine medicinal materials is stable, the curative effect is ensured, and on the other hand, the sufficient supply of medicinal sources is ensured, and the popularization and the application are facilitated.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine foot bath composition for treating dysmenorrhea and a preparation method thereof.
In order to achieve the above purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine foot bath composition for treating dysmenorrhea is prepared from the following raw materials in parts by weight: 18-22 parts of Chinese angelica, 10-14 parts of rheum officinale, 4-8 parts of pepper, 12-18 parts of salted fennel, 16-20 parts of amethyst, 9-11 parts of rhizoma sparganii, 9-11 parts of rhizoma curcumae, 4-8 parts of ground beetle, 12-18 parts of mugwort leaf, 7-11 parts of fructus evodiae, 10-14 parts of notopterygium root, 9-15 parts of rhizoma atractylodis, 3-7 parts of garden balsam stem, 5-13 parts of ligusticum wallichii and 12-18 parts of red paeony root.
In order to further realize the invention, the invention is prepared from the following raw materials in parts by weight: 20 parts of Chinese angelica, 12 parts of rheum officinale, 6 parts of pepper, 15 parts of salted fennel, 18 parts of amethyst, 10 parts of rhizoma sparganii, 10 parts of rhizoma curcumae, 6 parts of ground beetle, 15 parts of folium artemisiae argyi, 9 parts of fructus evodiae, 15 parts of notopterygium root, 12 parts of rhizoma atractylodis, 5 parts of garden balsam stem, 9 parts of ligusticum wallichii and 15 parts of red paeony root.
To further carry out the invention, powders, decoctions, solutions, concentrates, pastes or effervescent formulations are produced therefrom.
A method for preparing a traditional Chinese medicine foot bath liquid by using a traditional Chinese medicine foot bath composition for treating dysmenorrhea, which comprises the following steps:
A. respectively weighing the raw materials in the traditional Chinese medicine foot bath composition, and mixing to obtain a traditional Chinese medicine mixture;
B. pulverizing the Chinese medicinal mixture to 300-500 mesh, and performing gradient heating sterilization treatment comprising three gradients:
a first gradient: sterilizing at 75-85deg.C at a heating rate of 5-10deg.C/min for 5-10min;
a second gradient: sterilizing at 105-108 deg.c at 5-10 deg.c/min for 15-30min;
third gradient: sterilizing at 135-145 deg.C at 3-6deg.C/min for 10-15min;
C. packaging the traditional Chinese medicine mixture after the completion of gradient heating sterilization to obtain a medicine powder bag;
D. mixing the medicinal powder bag and water at a weight ratio of 1:3-5, and decocting for 15-20min, or soaking the medicinal powder bag and boiling water at a weight ratio of 1:3-5 for 25-30min to obtain the traditional Chinese medicine foot bath liquid.
The treatment mechanism of the invention:
from the traditional medical perspective, dysmenorrhea belongs to ' menstruation abdominal pain ', and is first seen in the ' Jinkui Mi Miao, women's miscellaneous diseases and pulse syndrome and treatment ' menstruation water disadvantage, rare women's full pain ' and one month's menstruation ' in Zhang Zhongjing instead. Clinically, the dysmenorrheal is caused by qi and blood of the uterus, and is caused by cold-dampness stasis clinically, regardless of the cause of the disease, the dysmenorrheal is caused by the obstruction of qi and blood of the uterus.
Dysmenorrhoea is located in uterus and changes in qi and blood. From the meridian point of view, dysmenorrhea mainly occurs in close relation with the thoroughfare and conception vessels and the three yin meridians of the foot (spleen of taiyin, liver of jueyin, kidney of shaoyin). When the two thoroughfare vessels are all from female cells, the thoroughfare vessels are in excess of the blood, so that the thoroughfare vessels are in excess of the blood, the qi and blood are in harmony, otherwise, the menstrual flow is not blocked, and the condition is abnormal, as in the case of abdominal pain due to the lunar water of women in the theory of disease and the treatment of women's miscellaneous diseases, the blood and qi are mostly damaged by the labor, so that the body is deficient, qi is blocked in the collaterals by wind cooling, and the thoroughfare vessels are damaged. Therefore, the dysmenorrheal is closely related to the thoroughfare vessels and conception vessels. The three yin meridians of the foot intersect with the two thoroughfare vessels, thereby indirectly connecting with the uterus and participating in the coordination of the qi and blood of the uterus. If the cold-dampness is affected, it can cause obstruction of the channels and collaterals of the three yin channels of the foot, which can further affect the qi and blood of the uterus to cause dysmenorrhea. From the viewpoint of viscera, the normal functioning of uterus is related to the kidney, liver and spleen, wherein the liver's dredging and discharging are involved in regulating the qi and blood of uterus, so the dysmenorrheal is most closely related to the liver. Liver is the heart of blood and stores blood, which is the junction for female physiological regulation. As Wang Bing notes, "liver stores blood, blood is transported to the meridians by movement of people, and blood is collected to the liver by static people". Liver is the viscera storing blood, yin of body is used yang, and is connected with the pulse of thoroughfare vessel, and the circulatory milk collaterals run off the lower abdomen and encircle the pudendum. So the blood in uterus is periodically preserved and discharged, and is regulated by the function of liver qi dredging. Therefore, liver failing to drain qi can cause dysmenorrhoea due to obstruction of qi and blood in uterus. Second, dysmenorrhea is also closely related to spleen and kidney. Kidneys pass through the lumbar spine of the epigastrium and the epigastrium, kidneys store essence and are mainly connected with kidneys, and kidney deficiency can not nourish the uterus and can cause gloomy and pain. Spleen is the source of acquired body resistance and qi and blood, and spleen deficiency and deficiency of qi and blood can cause pain due to lack of nourishment of uterus. All three zang organs are yin and qi-phase, and often suffer from cold-dampness and dysfunction.
Traditional Chinese medicine considers that dysmenorrheal is mainly caused by cold-dampness stagnation in uterus and unsmooth qi and blood circulation, so that the effects of warming channels, dispelling cold, eliminating dampness, promoting blood circulation, removing blood stasis and relieving pain are key for treating the disease. In the self-made prescription, purple Dan Yingxing is warm and heavy, and guides all the medicines to the Chong and ren meridians directly, and evodia rutaecarpa enters the kidney meridian, warms the kidney, warms the uterus, dispels cold and relieves pain, pricklyash peel enters the spleen and stomach of middle-jiao, warms middle-jiao and dispels cold, and fennel warms the kidney, warms the liver, moves qi and relieves pain. The worm herbs are good in moving, activating blood and dissolving stasis, inducing menstruation and dredging collaterals. The medicines are combined together, and then the skin striae are relaxed by the action of heat, so that the medicine is beneficial to expelling cold evil, and is beneficial to the medicine to permeate into skin and acupoints through the rapidly expanded pores, thereby directly acting on uterus, kidney liver spleen plantar reflex area to smooth uterus qi and blood, and circulating foot three yin channels of feet to reach uterus, thereby promoting uterus blood circulation, improving uterine ischemia and hypoxia, relieving channels and collaterals to relieve pain, and playing roles of activating blood circulation to remove stasis, regulating menstruation and regulating qi, dispelling cold and relieving pain. In addition, the organs of each part of the human body are provided with corresponding projection areas on the sole, so that the foot can be soaked by the traditional Chinese medicine, and the corresponding reflex areas of the foot, especially the brain, cerebellum brainstem, frontal sinus, celiac plexus and bipedal insomnia point, can be stimulated, the blood circulation of the foot can be promoted, the local muscle tension can be reduced, the fatigue can be eliminated, the channels and collaterals can be dredged, yin and yang can be regulated, viscera can be regulated, metabolism can be improved, the vegetative nerve function can be recovered to a normal state, and the purposes of eliminating diseases and strengthening body can be achieved.
The formula principle of the invention:
the uterus and the kidney, liver and spleen closely related to the functions of the uterus have corresponding reflex areas on the sole, the three yin meridians of the foot which are related to the uterus are initiated on the foot, and the medicine can directly act on the corresponding reflex areas, acupoints and meridians during foot bath so as to achieve the aim of treatment. The traditional Chinese medicine foot bath composition has the advantages that the Fluoritum is sweet in quality, is good for walking down the coke, warms the uterus and dissipates cold (regulates and supplements thoroughfare and conception vessels), the angelica Gan Wenbu is moist, nourishes blood and activates blood, regulates menstruation and relieves pain, and the Fluoritum are monarch drugs together to relieve dysmenorrheal of Gong Hanning. Evodia rutaecarpa has effects of dispelling cold and relieving pain, warming middle-jiao and eliminating dampness, and fructus Zanthoxyli enters spleen and stomach in middle-jiao, warming middle-jiao and dispelling cold, and removing dampness and relieving pain; rhizoma Sparganii is the qi-flowing in blood and rhizoma Curcumae is the qi-flowing in blood, and the two herbs are mutually combined to break blood, promote qi circulation, remove blood stasis and relieve pain. The four medicines are ministerial medicines together, enhance the analgesic effect of the monarch medicines, and remove blood stasis and dampness caused by cold coagulation. Eupolyphaga Seu Steleophaga has effects of removing blood stasis, removing food retention in Huang Hangyu, rhizoma Atractylodis with effects of eliminating dampness and dispelling cold, notopterygii rhizoma with effects of dispelling cold and eliminating dampness, herba speranskiae tuberculatae with effects of dispelling pathogenic wind and removing dampness, promoting blood circulation and removing blood stasis, and radix et rhizoma Rhei with effects of cold nature can be used as adjuvant drug for treating pungent and warm nature. Mugwort leaf warms the channel to dispel cold, regulates the channel to alleviate pain. Fennel warms kidney and liver, moves qi and relieves pain, both herbs enter lower jiao and direct all the herbs to the lower abdomen. All the medicines are combined together to achieve the effects of dispelling cold, removing dampness, removing blood stasis and relieving pain, and can be used for treating dysmenorrhea caused by cold-dampness stagnation in uterus.
Compared with the prior art, the invention has the beneficial effects that:
1. the prescription selects Gansu genuine medicinal materials such as angelica, rheum officinale, notopterygium root and the like, and the genuine medicinal materials are excellent in variety, are prepared with good examination, have outstanding curative effect and regional characteristics, are the root cause for ensuring the curative effect of the traditional Chinese medicine, and have stable medicine quality.
The contents of the medicines for treating dysmenorrhea, the main symptoms and the like are subjected to standardization treatment in clinic, so that the symptom type distribution trend and the medicine trend of dysmenorrhea are obtained, and the result shows that the Chinese angelica is used as a core medicine. The Chinese angelica can exert curative effects by improving hemorheology, regulating neuroendocrine hormone, reducing calcium ions, regulating immunity and the like, and can treat dysmenorrhea.
2. Most of the insect herbs are blood and meat with a feeling, and have the effects of promoting blood circulation, removing blood stasis, dispelling wind, removing obstruction in collaterals, calming wind, relieving spasm and the like, and the addition of the ground beetle herb takes the effects of dispelling wind, removing pain, and the other side takes other medicines by virtue of the property of dredging collaterals and inducing menstruation to reach the disease place, so that the old blood of uterus is removed, and the stasis of thoroughfare and conception vessels is dispersed.
3. By combining the pathogenesis characteristics of dysmenorrhea, the medicine is selected in a targeted way, the cause is checked, the disease is treated, the root is solved, and the treatment is based on syndrome differentiation. The medicines are combined to produce synergistic effect, and the curative effect and the treatment effect of the medicines are improved. Da Huang is cold in nature, so it can be used to treat pungent and warm nature of all herbs, eliminate or alleviate toxic and side effects, and has more scientific compatibility.
4. The liquid medicine can be directly absorbed, can obviously shorten the course of disease, relieve pain, and has the health care effects of strengthening physique and preventing disease recurrence. The traditional Chinese medicine foot bath can also avoid bad taste caused by oral administration, and is more acceptable to patients. The acupoints of feet are mainly Shu points, well, spring points, transmission points, channels and collaterals are very sensitive to stimulus including cold, heat or medicine ions, and physiological and pathological information of viscera and organs of human body exist on reflecting areas of feet objectively, and the acupoints and reflecting areas are closely connected with viscera and organs of the whole body. The medicine ions and the medicine property in the foot bath liquid are distributed to the whole body and uterus parts through the channel conduction, thereby achieving the effects of transporting qi and blood, nourishing and defending yin and yang, dispelling cold and removing dampness, dredging channels and collaterals and relieving pain.
5. The prescription adopts the Chinese medicinal materials with high quality and price, the burden of patients is light, and the acceptance is high.
Detailed Description
The invention is further described in connection with the following detailed description.
A traditional Chinese medicine foot bath composition for treating dysmenorrhea is prepared from the following raw materials in parts by weight: 18-22 parts of Chinese angelica, 10-14 parts of rheum officinale, 4-8 parts of pepper, 12-18 parts of salted fennel, 16-20 parts of amethyst, 9-11 parts of rhizoma sparganii, 9-11 parts of rhizoma curcumae, 4-8 parts of ground beetle, 12-18 parts of mugwort leaf, 7-11 parts of fructus evodiae, 10-14 parts of notopterygium root, 9-15 parts of rhizoma atractylodis, 3-7 parts of garden balsam stem, 5-13 parts of ligusticum wallichii and 12-18 parts of red paeony root.
It can be made into powder, decoction, solution, concentrate, paste or effervescent.
A method for preparing traditional Chinese medicine foot bath liquid by using the traditional Chinese medicine foot bath composition for treating dysmenorrhea comprises the following steps:
A. respectively weighing the raw materials in the traditional Chinese medicine foot bath composition, and mixing to obtain a traditional Chinese medicine mixture;
B. pulverizing the Chinese medicinal mixture to 300-500 mesh, and performing gradient heating sterilization treatment comprising three gradients:
a first gradient: sterilizing at 75-85deg.C at a heating rate of 5-10deg.C/min for 5-10min;
a second gradient: sterilizing at 105-108 deg.c at 5-10 deg.c/min for 15-30min;
third gradient: sterilizing at 135-145 deg.C at 3-6deg.C/min for 10-15min;
C. packaging the traditional Chinese medicine mixture after the completion of gradient heating sterilization to obtain a medicine powder bag;
D. mixing the medicinal powder bag and water at a weight ratio of 1:3-5, and decocting for 15-20min, or soaking the medicinal powder bag and boiling water at a weight ratio of 1:3-5 for 25-30min to obtain the traditional Chinese medicine foot bath liquid.
Example 1:
a traditional Chinese medicine foot bath composition for treating dysmenorrhea is prepared from the following raw materials in parts by weight: 18g of Chinese angelica, 10g of rheum officinale, 4g of pepper, 12g of salted fennel, 16g of amethyst, 9g of rhizoma sparganii, 9g of rhizoma curcumae, 4g of ground beetle, 12g of folium artemisiae argyi, 7g of fructus evodiae, 10g of notopterygium root, 9g of rhizoma atractylodis, 3g of garden balsam stem, 5g of ligusticum wallichii and 12g of red paeony root.
Example 2:
a traditional Chinese medicine foot bath composition for treating dysmenorrhea is prepared from the following raw materials in parts by weight: 22g of Chinese angelica, 14g of rheum officinale, 8g of pepper, 18g of salted fennel, 20g of amethyst, 11g of rhizoma sparganii, 11g of rhizoma curcumae, 8g of ground beetle, 18g of folium artemisiae argyi, 11g of fructus evodiae, 14g of notopterygium root, 15g of rhizoma atractylodis, 7g of garden balsam stem, 13g of ligusticum wallichii and 18g of red paeony root.
Example 3:
a traditional Chinese medicine foot bath composition for treating dysmenorrhea is prepared from the following raw materials in parts by weight: 20g of Chinese angelica, 12g of rheum officinale, 6g of pepper, 15g of salted fennel, 18g of amethyst, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 6g of ground beetle, 15g of folium artemisiae argyi, 9g of fructus evodiae, 15g of notopterygium root, 12g of rhizoma atractylodis, 5g of garden balsam stem, 9g of ligusticum wallichii and 15g of red paeony root.
Example 4:
a method for preparing a traditional Chinese medicine foot bath liquid by using a traditional Chinese medicine foot bath composition for treating dysmenorrhea, which comprises the following steps:
A. respectively weighing the raw materials in the traditional Chinese medicine foot bath composition, and mixing to obtain a traditional Chinese medicine mixture;
B. pulverizing the Chinese medicinal mixture to 300 meshes, and performing gradient heating sterilization treatment comprising three gradients:
a first gradient: the sterilization temperature is 75 ℃, the heating rate is 5 ℃/min, and the sterilization time is 5min;
a second gradient: the sterilization temperature is 105 ℃, the heating rate is 5 ℃/min, and the sterilization time is 15min;
third gradient: the sterilization temperature is 135 ℃, the heating rate is 3 ℃/min, and the sterilization time is 10min;
C. packaging the traditional Chinese medicine mixture after the completion of gradient heating sterilization to obtain a medicine powder bag;
D. mixing the medicinal powder bag and water according to the weight ratio of 1:3, and decocting for 15min to obtain the traditional Chinese medicine foot bath liquid.
Example 5:
a method for preparing a traditional Chinese medicine foot bath liquid by using a traditional Chinese medicine foot bath composition for treating dysmenorrhea, which comprises the following steps:
A. respectively weighing the raw materials in the traditional Chinese medicine foot bath composition, and mixing to obtain a traditional Chinese medicine mixture;
B. pulverizing the Chinese medicinal mixture to 500 meshes, and performing gradient heating sterilization treatment comprising three gradients:
a first gradient: the sterilization temperature is 85 ℃, the heating rate is 10 ℃/min, and the sterilization time is 10min;
a second gradient: the sterilization temperature is 108 ℃, the heating rate is 10 ℃/min, and the sterilization time is 30min;
third gradient: the sterilization temperature is 145 ℃, the heating rate is 6 ℃/min, and the sterilization time is 15min;
C. packaging the traditional Chinese medicine mixture after the completion of gradient heating sterilization to obtain a medicine powder bag;
D. mixing the medicinal powder bag and water according to a weight ratio of 1:5, and decocting for 20min to obtain the traditional Chinese medicine foot bath liquid.
Example 6:
a method for preparing traditional Chinese medicine foot bath liquid by using the traditional Chinese medicine foot bath composition for treating dysmenorrhea comprises the following steps:
A. respectively weighing the raw materials in the traditional Chinese medicine foot bath composition, and mixing to obtain a traditional Chinese medicine mixture;
B. pulverizing the Chinese medicinal mixture to 400 meshes, and performing gradient heating sterilization treatment which comprises three gradients:
a first gradient: the sterilization temperature is 80 ℃, the heating rate is 8 ℃/min, and the sterilization time is 8min;
a second gradient: the sterilization temperature is 103 ℃, the heating rate is 8 ℃/min, and the sterilization time is 25min;
third gradient: the sterilization temperature is 140 ℃, the heating rate is 5 ℃/min, and the sterilization time is 12min;
C. packaging the traditional Chinese medicine mixture after the completion of gradient heating sterilization to obtain a medicine powder bag;
D. mixing the medicinal powder bag and water according to the weight ratio of 1:4, and decocting for 17min to obtain the traditional Chinese medicine foot bath liquid.
Example 7:
a method for preparing a traditional Chinese medicine foot bath liquid by using a traditional Chinese medicine foot bath composition for treating dysmenorrhea, which comprises the following steps:
A. respectively weighing the raw materials in the traditional Chinese medicine foot bath composition, and mixing to obtain a traditional Chinese medicine mixture;
B. pulverizing the Chinese medicinal mixture to 300 meshes, and performing gradient heating sterilization treatment comprising three gradients:
a first gradient: the sterilization temperature is 75 ℃, the heating rate is 5 ℃/min, and the sterilization time is 5min;
a second gradient: the sterilization temperature is 105 ℃, the heating rate is 5 ℃/min, and the sterilization time is 15min;
third gradient: the sterilization temperature is 135 ℃, the heating rate is 3 ℃/min, and the sterilization time is 10min;
C. packaging the traditional Chinese medicine mixture after the completion of gradient heating sterilization to obtain a medicine powder bag;
D. soaking the medicinal powder bag and boiling water for 25min according to the weight ratio of 1:3 to obtain the traditional Chinese medicine foot bath liquid.
Example 8:
a method for preparing a traditional Chinese medicine foot bath liquid by using a traditional Chinese medicine foot bath composition for treating dysmenorrhea, which comprises the following steps:
A. respectively weighing the raw materials in the traditional Chinese medicine foot bath composition, and mixing to obtain a traditional Chinese medicine mixture;
B. pulverizing the Chinese medicinal mixture to 500 meshes, and performing gradient heating sterilization treatment comprising three gradients:
a first gradient: the sterilization temperature is 85 ℃, the heating rate is 10 ℃/min, and the sterilization time is 10min;
a second gradient: the sterilization temperature is 108 ℃, the heating rate is 10 ℃/min, and the sterilization time is 30min;
third gradient: the sterilization temperature is 145 ℃, the heating rate is 6 ℃/min, and the sterilization time is 15min;
C. packaging the traditional Chinese medicine mixture after the completion of gradient heating sterilization to obtain a medicine powder bag;
D. soaking the medicinal powder bag with boiling water at a weight ratio of 1:5 for 30min to obtain the traditional Chinese medicine foot bath liquid.
Example 9:
a method for preparing traditional Chinese medicine foot bath liquid by using the traditional Chinese medicine foot bath composition for treating dysmenorrhea comprises the following steps:
A. respectively weighing the raw materials in the traditional Chinese medicine foot bath composition, and mixing to obtain a traditional Chinese medicine mixture;
B. pulverizing the Chinese medicinal mixture to 400 meshes, and performing gradient heating sterilization treatment which comprises three gradients:
a first gradient: the sterilization temperature is 80 ℃, the heating rate is 8 ℃/min, and the sterilization time is 8min;
a second gradient: the sterilization temperature is 103 ℃, the heating rate is 8 ℃/min, and the sterilization time is 25min;
third gradient: the sterilization temperature is 140 ℃, the heating rate is 5 ℃/min, and the sterilization time is 12min;
C. packaging the traditional Chinese medicine mixture after the completion of gradient heating sterilization to obtain a medicine powder bag;
D. soaking the medicinal powder bag and boiling water for 28min according to the weight ratio of 1:4 to obtain the traditional Chinese medicine foot bath liquid.
Use contraindications: severely damaged foot skin.
Clinical test example:
1. case selection range:
150 cases of cold-dampness stagnation type dysmenorrhea patients with complete follow-up data of three hospital clinics and inpatients are selected. Of these, 50 cases of primary dysmenorrhea, 50 cases of inter-abnormal dysmenorrhea and 50 cases of other types of dysmenorrhea.
2. Curative effect judgment criteria:
and (3) curing: the abdominal pain disappears during menstrual period or before and after menstrual period, and the symptoms completely disappear, so that the patients do not relapse within half a year.
The effect is shown: the abdominal pain during menstrual period or before and after menstrual period is obviously relieved, the accompanying symptoms are also relieved, and the analgesic is not needed to be taken.
The method is effective: can relieve abdominal pain during menstrual period or before and after menstrual period, and can be tolerated.
Invalidation: the symptoms are not improved after treatment.
3. The treatment method comprises the following steps:
on the basis of health guidance, 150 patients are given with the traditional Chinese medicine foot bath treatment, the traditional Chinese medicine foot bath liquid prepared by the traditional Chinese medicine foot bath composition of the example 3 through the method of the example 6 is used for 30 minutes each time once a day, and the foot bath treatment is started 3-5 days before the patient passes through, and three menstrual cycles are continued.
The dosage of the traditional Chinese medicine foot bath liquid for each foot bath treatment is one dose (500 ml), hot water is added according to the ratio of the hot water to the foot bath liquid=1:3, the bath soup is ensured to pass through the ankle, the temperature of the hot water is properly regulated according to the tolerance degree of a patient, the season and other factors, the regulated temperature is 40-45 ℃, and the soaking time is 30min, so that the whole body of the patient is slightly sweated. Foot bath is not carried out 30min before and after meals.
4. And (3) result statistics:
after 50 cases of primary dysmenorrhea patients are treated by the traditional Chinese medicine foot bath composition, 3 cases are clinically cured, 38 cases are effectively treated, 7 cases are effectively treated, 2 cases are effectively treated, the total effective rate is 96%, and the curative effect is obvious. After 50 cases of patients with dysmenorrhoea suffering from the internal diseases are treated, 1 case is clinically cured, 32 cases are effectively treated, 10 cases are effectively treated, 7 cases are effectively treated, the total effective rate is 86%, and the curative effect is obvious. After 50 other dysmenorrhea patients are treated, 2 cases are clinically cured, 34 cases are effectively treated, 8 cases are effectively treated, 6 cases are effectively treated, the total effective rate is 88%, and the curative effect is obvious.
5. Conclusion:
the traditional Chinese medicine foot bath composition can effectively improve inflammatory response, has positive effect on relieving pain, and does not have adverse reaction.
6. Typical cases:
case 1: the patient, 16 years old, was first diagnosed on 12 months and 27 days in 2020. The menstrual cycle is 5-6 d/27-28 d, the quantity is small, the blood is dark red, and the blood is cloted. Last menstruation: 12 months and 4 days 2020. Before and after menstruation, pain relieving medicine should be orally taken for severe cases, and pain relieving medicine should be added gradually in the last half year, and the lower abdomen and waist become cool, tired and debilitated, aversion to cold, cold limbs, pale and dark tongue with teeth marks, white coating and deep and slow pulse. The traditional body building and plain preference for cold drink. Pelvic color ultrasound: no obvious abnormal echoes were seen in the uterus and double accessory areas. Western diagnosis: dysmenorrhea. Diagnosis of traditional Chinese medicine: abdominal pain during menstruation, cold-dampness congealing and blood stagnation in uterus. For warming channel, dispelling cold, eliminating dampness, promoting blood circulation, removing blood stasis and relieving pain. The traditional Chinese medicine foot bath liquid prepared in the examples 2 and 6 of the invention is given for 7 doses, 1 dose daily from 3 days before menstruation. Order to fasted, keep fresh and cool, pay attention to keep warm. The symptoms completely disappear after three treatment courses, and no recurrence occurs for two years.
Case 2: zhang Mou female, free professional, age 40. The patient was treated in 2021, 1 and 26. Menstrual pain appears before the age of 13 years and 4 years, waist and abdomen pain is felt before 7d, cold pain of lower abdomen, sweating and vomiting, cold limbs, bedridden, pain relieving tablets for primary administration can be relieved, subsequent administration is ineffective, and the pain degree is aggravated year by year. One year and a half ago diagnosis is made as right ovarian chocolate cyst, stripping operation is carried out, and manyule is placed in the uterine cavity after operation. The doctor is 10 months after operation, symptoms recur from the feeling of 3 months later, the abdominal pain is hard to endure during menstruation, the tongue is tender, the tongue coating is white, and the pulse is deep and thin. The symptoms are congealing and congealing cold and blood stagnation in uterus. The method is to warm channel, dispel cold, remove dampness, activate blood, remove stasis and relieve pain. The traditional Chinese medicine foot bath liquid prepared in the examples 1 and 4 of the invention is given 7 doses, 1 time a day from 3 days before menstruation. Order to fasted, keep fresh and cool, pay attention to keep warm. The medicine is already applied, the abdominal pain is greatly reduced, and the medicine can work normally. The patient is conditioned for 3 months, so that dysmenorrhea disappears and the patient does not develop.
Claims (4)
1. A traditional Chinese medicine foot bath composition for treating dysmenorrhea is characterized by being prepared from the following raw materials in parts by weight: 18-22 parts of Chinese angelica, 10-14 parts of rheum officinale, 4-8 parts of pepper, 12-18 parts of salted fennel, 16-20 parts of amethyst, 9-11 parts of rhizoma sparganii, 9-11 parts of rhizoma curcumae, 4-8 parts of ground beetle, 12-18 parts of mugwort leaf, 7-11 parts of fructus evodiae, 10-14 parts of notopterygium root, 9-15 parts of rhizoma atractylodis, 3-7 parts of garden balsam stem, 5-13 parts of ligusticum wallichii and 12-18 parts of red paeony root.
2. The traditional Chinese medicine foot bath composition for treating dysmenorrhea, as claimed in claim 1, is characterized by being prepared from the following raw materials in parts by weight: 20 parts of Chinese angelica, 12 parts of rheum officinale, 6 parts of pepper, 15 parts of salted fennel, 18 parts of amethyst, 10 parts of rhizoma sparganii, 10 parts of rhizoma curcumae, 6 parts of ground beetle, 15 parts of folium artemisiae argyi, 9 parts of fructus evodiae, 15 parts of notopterygium root, 12 parts of rhizoma atractylodis, 5 parts of garden balsam stem, 9 parts of ligusticum wallichii and 15 parts of red paeony root.
3. The traditional Chinese medicine foot bath composition for treating dysmenorrhea according to claim 1 or 2, wherein: it can be made into powder, decoction, solution, concentrate, paste or effervescent.
4. A method for preparing a traditional Chinese medicine foot bath liquid by using the traditional Chinese medicine foot bath composition for treating dysmenorrhea according to claim 1 or 2, which is characterized by comprising the following steps:
A. respectively weighing the raw materials in the traditional Chinese medicine foot bath composition, and mixing to obtain a traditional Chinese medicine mixture;
B. pulverizing the Chinese medicinal mixture to 300-500 mesh, and performing gradient heating sterilization treatment comprising three gradients:
a first gradient: sterilizing at 75-85deg.C at a heating rate of 5-10deg.C/min for 5-10min;
a second gradient: sterilizing at 105-108 deg.c at 5-10 deg.c/min for 15-30min;
third gradient: sterilizing at 135-145 deg.C at 3-6deg.C/min for 10-15min;
C. packaging the traditional Chinese medicine mixture after the completion of gradient heating sterilization to obtain a medicine powder bag;
D. mixing the medicinal powder bag and water at a weight ratio of 1:3-5, and decocting for 15-20min, or soaking the medicinal powder bag and boiling water at a weight ratio of 1:3-5 for 25-30min to obtain the traditional Chinese medicine foot bath liquid.
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Application publication date: 20231010 |