CN116785000A - Preparation method of bone material implantation guide plate - Google Patents

Preparation method of bone material implantation guide plate Download PDF

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Publication number
CN116785000A
CN116785000A CN202210528188.1A CN202210528188A CN116785000A CN 116785000 A CN116785000 A CN 116785000A CN 202210528188 A CN202210528188 A CN 202210528188A CN 116785000 A CN116785000 A CN 116785000A
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bone
guide plate
implant
dimensional
implantation
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CN202210528188.1A
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蒋欣泉
顾晓宇
王洁
曾德良
曹玲燕
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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Abstract

The application discloses a preparation method of an bone material implantation guide plate, which comprises the following steps: 1) Acquiring a patient upper jaw three-dimensional model and a patient lower jaw three-dimensional model by utilizing a three-dimensional scanning technology, and acquiring three-dimensional position relations of upper and lower jaw dentitions under different occlusion states; 2) Based on the three-dimensional position relation, repairing is used as guiding to simulate the ideal gingiva penetrating position of the patient future crown prosthesis and the three-dimensional position in bone tissue where the implant is positioned in computer software, and an implant operation guide plate is designed in the three-dimensional software to form a diagnosis model and guide plate data; 3) The implantation operation guide plate is transformed into an bone material implantation guide plate; 4) And obtaining the bone material implantation guide plate by a three-dimensional printing method. The bone material implantation guide plate manufactured by the application can rapidly and accurately indicate the outline shape of bone implantation materials or autologous bone tissue implantation.

Description

Preparation method of bone material implantation guide plate
Technical Field
The application relates to the technical field of medical machinery manufacturing, in particular to a preparation method of an bone material implantation guide plate.
Background
With the progress of oral treatment technology and the improvement of oral health requirements of people, more and more patients choose to implant and repair missing teeth. The purpose of the implant is to improve the chewing function and the beautiful effect of the patient, and relates to the comprehensive treatment of the crown restoration, the periodontal soft tissue and the bone tissue. The implant design principle with the repair as the guide is that the position of the implant is standard with the position of the future crown prosthesis, and a certain amount of bone tissue contour is needed around the implant to ensure enough implant-bone combination and soft tissue contour around the prosthesis. However, the loss of bone tissue height and width is unavoidable after the loss of teeth, and even some patients can lose the alveolar bone of the future implantation site in advance and absorb unevenly due to various dental loss reasons including, but not limited to, periodontitis, which affect the implantation position of the implant and the effect of the future crown restoration, so that one of the preconditions of oral implantation is to restore or reconstruct a good bone tissue contour.
A common method of restoring the alveolar bone shape in clinical practice is guided bone regeneration. The bone regeneration guiding technology is a bone increment technology which utilizes bone grafting materials and/or biological membranes to guide bone cells to grow into and rapidly bone, and the control of the quantity and the outline of the implanted bone grafting materials in clinic at present mostly depends on clinical experience, and the implantation operation technology has high sensitivity and lacks operation guiding. The improper bone meal implant and the remodeling of the contour affect the bone grafting effect and soft tissue aesthetics around the long-term implant superstructure crown restoration. Therefore, bone material is required to be implanted into the guide plate for guiding during bone grafting, so as to reduce operation sensitivity and improve long-term clinical effect.
Disclosure of Invention
The application aims to provide a preparation method of a bone material implantation guide plate, so that bone powder implantation can be guided accurately and stably.
In a first aspect of the present application, there is provided a method for manufacturing an bone material implantation guide plate, the method comprising the steps of:
1) Acquiring a patient upper jaw three-dimensional model and a patient lower jaw three-dimensional model by utilizing a three-dimensional scanning technology, and acquiring three-dimensional position relations of upper and lower jaw dentitions under different occlusion states;
2) Based on the three-dimensional position relation, repairing is used as guiding to simulate the ideal gingiva penetrating position of the patient future crown prosthesis and the three-dimensional position in bone tissue where the corresponding implant is positioned in computer software, and an implantation operation guide plate is designed in the three-dimensional software to form a diagnosis model and guide plate data;
3) The implant surgery guide plate is transformed into an bone material implant guide plate, which comprises the following steps:
i) Calculating the required bone tissue outline based on the ideal implant space position of the diagnostic model, and smoothing and constructing the bone tissue outline around the implant by using a computer graphics difference calculation method;
ii) using an offset command of computer graphics to shift the designed bone tissue profile data by 1-2mm to reach the thickness of the guide plate, forming a bone defect recovery area of the bone material implantation guide plate;
iii) Three-dimensional data fusion is carried out on the data of the implantation guide plate and the bone defect recovery area, a cylindrical bone powder implantation channel with the diameter of 5mm is constructed at the top mucosa of the alveolar ridge of the tooth-missing area, and the bone material implantation guide plate is formed through three-dimensional graphic adjustment;
4) The bone material implantation guide plate of the resin material is obtained by a three-dimensional printing method.
In another preferred embodiment, the different bite states are a middle bite, a forward bite, a left side bite, a right side bite.
In another preferred example, the three-dimensional positional relationship of the upper and lower dentitions in different occlusion states is obtained by:
and (3) positioning the occlusion process of the patient through the occlusion relationship between the upper jaw and the lower jaw and the virtual jaw frame, or recording the maximum protrusion, the lateral and the central occlusion relationship of the patient by using silicone rubber in the mouth, manufacturing a plaster model in vitro, and carrying out three-dimensional scanning on the plaster model to obtain the three-dimensional position relationship between the upper jaw and the lower jaw in different occlusion states.
In another preferred embodiment, in step 2, the ideal position and shape of the crown prosthesis are designed by using dental prosthesis design software or according to the width, height and thickness of bone tissue in a computer through the positions of the upper and lower jaw dentitions in different occlusion relations, the implantation site and direction of the implant are designed based on the ideal position and shape, and the implantation operation guide plate is generated.
In the present application, the implant design software includes, but is not limited to, common implant design software such as denmark 3Shape software, noble clinical of Noble Biocare, and the like.
In another preferred embodiment, the implant surgical guide is tooth supported, mucosa supported or hybrid supported.
In another preferred embodiment, the bone tissue contour is guided by the position of the median occlusion crown prosthesis.
In another preferred embodiment, retrofitting the implant surgical guide to the bone material implant guide is performed at the implant site.
In another preferred embodiment, the bone tissue contour is based on the desired implant spatial location such that a desired bone width of 2-4mm and a suitable alveolar ridge height are formed around the implant.
In another preferred example, in the step i, 3-5 triangular surface patches which are most prominent at the bone tissue defect position reconstructed by CBCT are utilized, the alveolar bone surface skin is calculated by using a difference method, the relaxation smoothing treatment is carried out, and the space of surrounding sufficient bone tissue is planned for the implant according to the implant position, so that the bone tissue outline at the implant site is constructed.
In another preferred example, in the step i, 3-5 triangular surface patches which are most prominent on the bone tissue defect morphology surface reconstructed by CBCT are utilized, an ideal alveolar bone surface skin is reconstructed by using a difference method, loose smoothing treatment is carried out, and partial deformation treatment is carried out on the ideal alveolar bone surface skin according to the implant position, so that sufficient bone tissue space is formed around the implant, and the bone tissue outline around the implant is obtained.
In another preferred embodiment, in step ii, the width of bone tissue around the implant is defined according to the 3A2B principle, the outline of the defect area of the bone tissue is adjusted by using the local deformation function in computer software of computer graphics, and then the outline of the bone is offset by 1-2mm by using the offset function of computer graphics, so as to form the bone defect recovery area of the bone material implantation guide plate.
In another preferred example, in the step ii, the width of bone tissue around the implant is regulated according to the 3A2B principle, the outline of the bone tissue defect area is regulated by stretching transformation in computer graphics, and then the bone defect recovery area of the bone material implantation guide plate is formed by shifting 1-2mm by using the computer graphics offset function.
As known to those skilled in the art, the 3A-2B principle is the standard for implant implantation locations. The specific contents proposed by Fernando Rojas-Vizcaya in 2013 are: 3A refers to the bone level implant margin 3mm (vertical) from the root of the predicted prosthesis margin; 2B means that there is at least 2mm (horizontally) in the labial lamina of the bone horizontal implant. Reference is made to: rojas-Vizcaya, f. (2013) Biological aspects as a rule for single implant displacement.the 3A-2B rule:a clinical report; j Prosthodont22 (7): 575-580.
In the application, the computer graphics is a common graphic processing method in many common reverse engineering software such as Geomagic studio software, and can sample, fill, bridge, shift, shell relaxation, surface structure and other operations on the three-dimensional data graphics.
In a second aspect of the application, there is provided an bone material implantation guide prepared by the preparation method of the first aspect.
In a third aspect of the application, there is provided an apparatus comprising:
the three-dimensional model providing module of the crown restoration is used for providing the position of the crown restoration and the peripheral gum morphology;
the bone defect area construction module is used for reversely pushing the outline shape of the alveolar bone according to the position of the crown restoration and the position of the implant;
the bone meal implantation channel module is used for constructing an implantation path on the bone tissue defect indication part module.
In another preferred embodiment, the apparatus further comprises: virtual jaw frame, upper and lower jaw three-dimensional model, periodontal tissue regeneration operation baffle preparation module.
In the application, the digitizing technology is introduced into the bone implantation process, the position of the future crown restoration body is considered, the required bone bow outline range is also considered, and then the bone material implantation guide plate is designed, so that the bone implantation range and the bone implantation position are effectively guided, and the autologous bone material or commercial bone tissue can be stably and accurately implanted.
It is understood that within the scope of the present application, the above-described technical features of the present application and technical features specifically described below (e.g., in the examples) may be combined with each other to constitute new or preferred technical solutions. Each feature disclosed in the description may be replaced by alternative features serving the same, equivalent or similar purpose. And are limited to a space, and are not described in detail herein.
Drawings
FIG. 1 illustrates a method of preparing an bone material implantation guide of the present application.
Fig. 2 shows registration of a CBCT scanned jaw model with a dentition scan model.
Fig. 3 shows the design of the position of the crown prosthesis and the position of the implant according to the occlusion position relationship, and the implant guide plate 1 is formed.
Fig. 4 is a view of the bone defect area surface skin.
FIG. 5 is an illustration of an offset extrapolation offset of 1-2mm using computer graphics at a bone tissue defect to form a bone defect restoration area for an bone material implant guide.
Fig. 6 shows the guide plate 1 fitted with a bone defect restoration area to construct a bone meal implantation channel, forming a bone implantation guide plate 2.
Detailed Description
The inventor researches widely and intensively to develop a preparation method of a bone material implantation guide plate, wherein a three-dimensional scanning technology is utilized to obtain a maxillary three-dimensional model and a mandibular three-dimensional model of a patient, and CBCT scanning is utilized to obtain a maxillary bone and mandibular bone tissue three-dimensional model of the patient and then registration is carried out on the maxillary bone and mandibular bone tissue three-dimensional model of the patient and a dentition model; designing an implant implantation position based on the ideal position of the crown prosthesis, and designing a bone material implantation guide plate diagnosis model according to the bone tissue contour required around the implant implantation position; and designing a bone implantation guide plate taking dentition as a support, and acquiring the bone material implantation guide plate in a three-dimensional printing mode. The bone material implantation guide plate can rapidly and accurately indicate the outline shape of bone implantation materials or autologous bone tissue implantation. On this basis, the present application has been completed.
Terminology
Tooth implantation
Dental implant (Dental implant) refers to a Dental prosthesis that supports and retains a superior prosthesis based on a substructure implanted in bone tissue. Comprises a lower implantation structure and an upper crown prosthesis, and mainly aims at treatment work after tooth defect and deletion.
The implant is also called artificial implant, not true implant natural tooth, but by means of medical method, titanium metal with high compatibility with human bone is precisely designed to be made into cylinder or other shape similar to tooth root, and then is implanted into alveolar bone of tooth-missing area by means of surgical minor surgery, after 1-3 months, when artificial tooth root is combined with alveolar bone, crown restoration is made on artificial tooth root. The implant can obtain the repairing effect very similar to the functions, structures and attractive effects of the natural teeth, and has become the preferred repairing mode for more and more dental deficiency patients. Because of no harm to adjacent teeth, dental implants have been recognized by the oral medical community as the preferred way to repair missing teeth.
The implant is the best restoration mode after the teeth are missing, but sometimes the bone quantity is insufficient during the implant operation due to overlong missing teeth or excessive and/or uneven alveolar bone absorption around the teeth before the teeth are missing caused by periodontal disease, so that the operation of the implant is difficult to perform. Bone powder is used as bone implant material, and is filled in the alveoli and the missing tooth part in the operation to increase the height and thickness of the alveolar bone and provide good implant environment for implant implantation.
Oral cavity CBCT
CBCT is an abbreviation for Cone beam CT, i.e. Cone beam CT. The concept of cone beam projection computer tomograph is that the X-ray generator makes a ring DR (digital projection) around the projection object with a low radiation dose (typically bulb current around 10 milliamperes). And then, the data obtained in the 'intersection' after a plurality of (180-360) digital shots around the shot body are 'recombined' in a computer, and then a three-dimensional image is obtained.
Preparation method
As shown in FIG. 1, the preparation method of the bone material implantation guide plate comprises the following steps:
1) Acquiring a patient upper jaw three-dimensional model and a patient lower jaw three-dimensional model by utilizing a three-dimensional scanning technology, and acquiring three-dimensional position relations of upper and lower jaw dentitions under different occlusion states;
2) Based on the three-dimensional position relation, repairing is used as guiding to simulate the ideal gingiva penetrating position of the patient future crown prosthesis and the three-dimensional position in bone tissue where the corresponding implant is positioned in computer software, and an implantation operation guide plate is designed in the three-dimensional software to form a diagnosis model and guide plate 1 data;
3) The traditional implantation guide plate (implantation operation guide plate 1) is changed into an bone material implantation guide plate (guide plate 2), and the specific steps are as follows:
i) Smoothing and constructing the bone tissue outline at the implantation site by using a difference calculation method of computational graphics based on the bone tissue outline of the diagnostic model;
ii) according to the width requirement of bone tissue around the implant, using a computational graph stretching transformation method at the bone tissue defect position, and using a computational graph offset (extrapolation) of 1-2mm at the bone tissue defect position to form a bone defect recovery area of the bone material implantation guide plate;
iii) Fitting the guide plate 1 with the recovery area, and constructing a bone meal implantation channel to form a guide plate 2, namely a bone material implantation guide plate;
4) And obtaining the bone material implantation guide plate by a three-dimensional printing method.
According to the application, a digitizing technology is introduced into a bone implantation process, not only the position of a future crown restoration is considered, but also the required outline range of the bone is considered, and then the bone implantation guide plate is designed to effectively guide the bone implantation range and position, so that the autologous bone material or the commercial bone implantation material can be stably and accurately implanted. Compared with the prior art, the application can realize accurate and stable bone grafting, the range and the position of the implant are known before the bone grafting, and the bone grafting effect and the position of the crown prosthesis in the future can be predicted. If too much bone powder needs to be implanted or the implantation position is difficult to stabilize, the problems of poor stability, excessive long-term absorption and the like of the later stage of the bone implantation of a patient can be caused, the problems can be considered when the position of the crown restoration is designed, and the bone shape profile is coordinated by changing the position of the crown restoration or changing the angle of a future planting base, so that the bad prognosis of the bone implantation or the need of secondary bone grafting is avoided.
The application will be further illustrated with reference to specific examples. It is to be understood that these examples are illustrative of the present application and are not intended to limit the scope of the present application. The experimental procedures, which do not address the specific conditions in the examples below, are generally carried out under conventional conditions or under conditions recommended by the manufacturer. Percentages and parts are weight percentages and parts unless otherwise indicated.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art. In addition, any methods and materials similar or equivalent to those described herein can be used in the methods of the present application. The preferred methods and materials described herein are presented for illustrative purposes only.
Examples
Preparation method of bone material implantation guide plate
1) And acquiring a patient upper jaw three-dimensional model and a patient lower jaw three-dimensional model by using a CBCT three-dimensional scanning technology, and acquiring three-dimensional position relations of upper and lower jaw dentitions under different occlusion states.
The CBCT scanned jaw model is registered with the dentition scan model as shown in fig. 2.
Specifically, a plaster model is manufactured in vitro through the occlusion process of a patient by the occlusion relationship of the upper jaw and the lower jaw and the positioning of the virtual jaw frame, or after the maximum protrusion, the lateral and the central occlusion relationship of the patient are recorded by using silicone rubber in the mouth, and the plaster model is subjected to three-dimensional scanning to obtain the three-dimensional position relationship of the upper jaw and the lower jaw dentition under different occlusion states.
2) Based on the three-dimensional position relation, the ideal gingiva penetrating position of the crown restoration body and the three-dimensional position of the bone tissue where the implant body is positioned are simulated in computer software by using restoration as guiding, and the implantation operation guide plate is designed in the three-dimensional software to form a diagnosis model and a guide plate 1, as shown in fig. 3.
Specifically, the position and the form of the crown restoration are designed by using implant design software in a computer or according to the width, the height and the thickness of bone tissues and through the positions of the upper jaw dentition and the lower jaw dentition under different occlusion relations, the implant implantation site and the direction are designed based on the positions and the forms, and an implant operation guide plate is generated. The implantation surgical guide is of a dental support type, a mucous membrane support type or a mixed support type.
The implant surgical guide is modified to bone material implant guide at the implant site.
3) The traditional implantation operation guide plate 1 is changed into a bone material implantation guide plate 2, and the specific steps are as follows
i) Based on the bone tissue outline of the diagnostic model, calculating the alveolar bone surface skin by using 3-5 triangular surface patch areas with the most prominent bone tissue defect parts reconstructed by CBCT and using a computer graphics difference calculation method, performing relaxation smoothing treatment, and constructing the bone tissue outline at the implantation site according to the implant position and the volume of surrounding sufficient bone tissues;
ii) defining the width of bone tissue around the implant according to the 3A2B principle, and forming a bone defect recovery area of the bone material implantation guide plate by using a computer graphics stretching transformation method at the bone tissue defect position and using offset function offset by 1-2mm at the bone tissue defect position according to the requirement of the width of bone tissue around the implant, as shown in figure 5;
iii) Fitting the guide plate 1 with the bone defect recovery area, wherein the bone powder implantation channel is constructed by the guide plate 1 except the bone tissue defect area, namely the implantation site area, and the guide plate 2 is formed, namely the bone material implantation guide plate, as shown in fig. 6;
4) And obtaining the bone material implantation guide plate by a three-dimensional printing method.
All documents mentioned in this disclosure are incorporated by reference in this disclosure as if each were individually incorporated by reference. Further, it will be appreciated that various changes and modifications may be made by those skilled in the art after reading the above teachings, and such equivalents are intended to fall within the scope of the application as defined in the appended claims.

Claims (10)

1. A method for preparing an implant guide plate of bone material, which is characterized by comprising the following steps:
1) Acquiring a patient upper jaw three-dimensional model and a patient lower jaw three-dimensional model by utilizing a three-dimensional scanning technology, and acquiring three-dimensional position relations of upper and lower jaw dentitions under different occlusion states;
2) Based on the three-dimensional position relation, repairing is used as guiding to simulate the ideal gingiva penetrating position of the patient future crown prosthesis and the three-dimensional position in bone tissue where the corresponding implant is positioned in computer software, and an implantation operation guide plate is designed in the three-dimensional software to form a diagnosis model and guide plate data;
3) The implant surgery guide plate is transformed into an bone material implant guide plate, which comprises the following steps:
i) Calculating the required bone tissue outline based on the ideal implant space position of the diagnostic model, and smoothing and constructing the bone tissue outline around the implant by using a computer graphics difference calculation method;
ii) using an offset command of computer graphics to shift the designed bone tissue profile data by 1-2mm to reach the thickness of the guide plate, forming a bone defect recovery area of the bone material implantation guide plate;
iii) Three-dimensional data fusion is carried out on the data of the implantation guide plate and the bone defect recovery area, a cylindrical bone powder implantation channel with the diameter of 5mm is constructed at the top mucosa of the alveolar ridge of the tooth-missing area, and the bone material implantation guide plate is formed through three-dimensional graphic adjustment;
4) The bone material implantation guide plate of the resin material is obtained by a three-dimensional printing method.
2. The method of claim 1, wherein the different bite states are center bite, forward bite, left side bite, right side bite.
3. The method of claim 1, wherein the three-dimensional positional relationship of the upper and lower dentitions in different occlusion states is obtained by:
and (3) positioning the occlusion process of the patient through the occlusion relationship between the upper jaw and the lower jaw and the virtual jaw frame, or recording the maximum protrusion, the lateral and the central occlusion relationship of the patient by using silicone rubber in the mouth, manufacturing a plaster model in vitro, and carrying out three-dimensional scanning on the plaster model to obtain the three-dimensional position relationship between the upper jaw and the lower jaw in different occlusion states.
4. The method according to claim 1, wherein in step 2, the ideal position and shape of the crown prosthesis are designed by the position of the upper and lower dentitions in different occlusion relations by using dental prosthesis design software in a computer, the implant implantation site and direction are designed based on the ideal position and shape, and the implant operation guide plate is generated.
5. The method of claim 4, wherein the implant surgical guide is tooth-supported, mucosa-supported, or hybrid-supported.
6. The method of claim 1, wherein the bone tissue contour is based on the desired implant space position such that a desired bone width of 2-4mm and a suitable alveolar ridge height are formed around the implant.
7. The preparation method of claim 1, wherein in the step i, 3-5 triangular surface patch areas most protruding from the bone tissue defect site reconstructed by CBCT are utilized, an alveolar bone surface skin is calculated by using a difference method, a relaxation smoothing treatment is performed, and a bone tissue outline at the implant site is constructed according to the implant position for which a space of sufficient bone tissue around the implant is planned.
8. The method of claim 1, wherein in step ii, the bone tissue width around the implant is defined according to 3A2B principle, the shape profile of the bone tissue defect area is adjusted by using the local deformation function in computer graphics computer software, and the bone shape profile is offset by 1-2mm by using the computer graphics offset function, so as to form the bone defect recovery area of the bone material implantation guide plate.
9. An bone material implantation guide plate prepared by the preparation method of any one of claims 1 to 6.
10. An apparatus, the apparatus comprising:
the three-dimensional model providing module of the crown restoration is used for providing the position of the crown restoration and the peripheral gum morphology;
the bone defect area construction module is used for reversely pushing the outline shape of the alveolar bone according to the position of the crown restoration and the position of the implant;
the bone meal implantation channel module is used for constructing an implantation path on the bone tissue defect indication part module.
CN202210528188.1A 2022-05-16 2022-05-16 Preparation method of bone material implantation guide plate Pending CN116785000A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117679142A (en) * 2023-12-25 2024-03-12 北京大学口腔医学院 Intraoral double-layer cortical bone piece bone grafting guide plate and manufacturing method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117679142A (en) * 2023-12-25 2024-03-12 北京大学口腔医学院 Intraoral double-layer cortical bone piece bone grafting guide plate and manufacturing method thereof

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