CN116784346A - Weeding composition containing mesosulfuron-methyl and application thereof - Google Patents

Abstract

The invention belongs to the field of pesticides, and particularly relates to a weeding composition containing mesosulfuron-methyl and application thereof. The weeding composition comprises an active ingredient A and an active ingredient B in herbicidally effective amounts, wherein the active ingredient A is mesosulfuron-methyl, and the active ingredient B is one or two of the following compounds: prometryn or simetryn. The composition can effectively prevent and remove weed problems such as Myrtle, chinese eaglewood, galium, veronica, etc., and has the characteristics of enlarging weed control spectrum, reducing application amount, generating synergistic effect, solving resistant weeds, etc.

Description

Weeding composition containing mesosulfuron-methyl and application thereof

Technical Field

The invention belongs to the field of pesticides, and particularly relates to a weeding composition containing mesosulfuron-methyl and application thereof.

Background

Chemical weeding is the most economical and effective means in farmland weed control, but long-term continuous high-dosage chemical herbicide with single variety or single action mode is easy to cause problems of weed resistance, resistance evolution and the like.

Mesosulfuron belongs to sulfonylurea high-efficiency herbicides, and acts by inhibiting acetolactate synthase, and is absorbed by roots and leaves of weeds and transmitted in plants, so that the weeds stop growing and die.

The reasonable compounding or compounding of the herbicide compound has the advantages of expanding the weed spectrum, improving the preventing and killing effect, delaying the occurrence and development of weed resistance and drug resistance, and the like, is one of the most effective methods for solving the problems, and still needs to develop a herbicide composition variety with high safety, broad herbicide spectrum, capability of generating synergistic effect and solving the problem of resistant weeds in production.

Disclosure of Invention

In order to solve the problems in the prior art, the invention provides a weeding composition containing mesosulfuron and application thereof. The composition can effectively prevent and remove weed problems such as Myrtle, chinese eaglewood, galium, veronica, etc., and has the characteristics of enlarging weed control spectrum, reducing application amount, generating synergistic effect, solving resistant weeds, etc.

A herbicidal composition comprising mesosulfuron, comprising a herbicidally effective amount of active ingredient a and active ingredient B, wherein the active ingredient a is mesosulfuron (CAS: 208465-21-8) and the active ingredient B is selected from one or two of the following compounds: prometryn (CAS: 7287-19-6) or cilexetil (CAS: 1014-70-6).

Wherein, the weight ratio of A to B in the weeding composition is 1:100-30:1, preferably 1:80-10:1, more preferably 1:50-1:1, and even more preferably 1:40-2:5.

The mass percentage of A and B in the weeding composition accounts for 1-95% of the total amount, preferably 10-80%.

The herbicidal composition further comprises conventional adjuvants including carriers and/or surfactants.

The term "carrier" as used herein means an organic or inorganic, natural or synthetic substance. They facilitate the application of the active ingredient, which carriers are generally inert and must be agriculturally acceptable, in particular by the treated plants. The carrier may be solid, such as clay, natural or synthetic silicate, silica, resin, wax, solid fertilizer, etc.; or liquid, such as water, alcohols, ketones, petroleum fractions, aromatic or waxy hydrocarbons, chlorinated hydrocarbons, liquefied gases, and the like.

Surfactants may include emulsifiers, dispersants or wetting agents, which may be ionic or nonionic. Examples which may be mentioned are salts of polyacrylic acid, lignosulfonates, salts of phenolsulfonic acid or naphthalenesulfonic acid, polymers of ethylene oxide with aliphatic alcohols or with aliphatic amines with substituted phenols, in particular alkylphenols or arylphenols, sulfosuccinates, taurine derivatives, in particular taurates, and phosphates of alcohols or of polyethylated phenols, alkylsulfonates, alkylaryl sulfonates, alkyl sulfates, lauryl ether sulfates, fatty alcohol sulfates, and also sulfated hexadecyl-, heptadeca-and octadecanols and sulfated fatty alcohol glycol ethers, furthermore condensates of naphthalene or naphthalenesulfonic acid with phenol and formaldehyde, polyoxyethylene octylphenyl ether, ethoxylated isooctylphenols, octylphenols or nonylphenols, alkylphenyl polyglycol ethers, tributylphenyl polyglycol ethers, tristearylphenyl polyglycol ethers, alkylaryl polyether alcohols, alcohol and fatty alcohol/ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ethers, sorbitol esters, lignin sulfite waste solutions, and also proteins, polysaccharides (e.g. methylcellulose), polyvinyl alcohol, hydrophobically modified polyvinyl pyrrolidone, polyvinyl alcohol carboxylate, polyvinyl pyrrolidone, and copolymers thereof. At least one surfactant is required to be present to facilitate the dispersion of the active ingredients in water and to enable them to be applied correctly to the plants.

The above-described compositions may also contain various other components such as protective colloids, binders, thickeners, thixotropic agents, penetrating agents, stabilizers, chelating agents, dyes, colorants and polymers.

The herbicidal composition further comprises at least one safener, preferably one or more of bisbenzoxazole acid (CAS: 163520-33-0), cyprosulfamide (CAS: 221667-31-8), pyraclonil (CAS: 135590-91-9), cloquintocet-mexyl (CAS: 99607-70-2), gibberellic acid (CAS: 7-06-5), furilazole (CAS: 121776-33-8), metacam (CAS: 129531-12-0).

The compositions of the present invention may be diluted by the user prior to use or used directly. The preparation can be prepared by common processing method, namely, mixing the active substance with liquid solvent or solid carrier, and adding one or more surfactants such as dispersing agent, stabilizer, wetting agent, adhesive, defoamer, etc.

The specific preparation of the weeding composition is dispersible oil suspending agent, water suspending agent, suspending emulsion, wettable powder, emulsifiable concentrate, water dispersible granule (dry suspending agent), water emulsion and microemulsion.

Briefly, the compositions of the present invention can be mixed with solid and liquid additives conventionally used in prior art formulations. The amount of the active ingredient used varies with the external conditions such as temperature, humidity, the nature of the herbicide used, and the like. It may have a large variation, for example between 0.001 and 2.0kg/ha, or more, of active substance, but preferably between 0.1 and 1kg/ha, in particular between 1 and 500 g/ha.

In the context of the present specification, if the abbreviated form of the generic name of the active compound is used, all customary derivatives, such as esters and salts, as well as isomers, in particular optical isomers, in particular one or more commercially available forms, are included in each case. If the generic name denotes esters or salts, all other customary derivatives are also included in each case, such as other esters and salts, free acids and neutral compounds, as well as isomers, in particular optical isomers, in particular one or more commercially available forms. The chemical name given to a compound means at least one compound covered by a common name, generally the preferred compound. In the case of sulfonamides such as sulfonylureas, salts also include salts formed by the exchange of cations with hydrogen atoms in the sulfonamide group. For example, 2-methyl-4-chloro derivatives include, but are not limited to: 2 methyl 4 chloro sodium salt, potassium salt, dimethyl ammonium salt, isopropyl amine salt, etc., 2 methyl 4 chloro methyl ester, ethyl ester, isooctyl ester, ethyl thioester, etc.; 2,4-D derivatives include, but are not limited to: 2,4-D salts such as sodium salt, potassium salt, dimethyl ammonium salt, triethanol ammonium salt, isopropyl amine salt, choline, etc., and 2,4-D esters such as methyl ester, ethyl ester, butyl ester, isooctyl ester, etc.

The invention also provides application of the weeding composition in weed control; and a method of controlling unwanted plant growth comprising applying the herbicidal composition to plants, plant parts, plant seeds or areas of plant growth.

In addition, the compositions of the invention can be applied by spraying onto the foliage of the plants to be treated, i.e. onto weeds, in particular onto surfaces which are infested or susceptible to infestation by weeds.

When the herbicidal composition of the present invention is applied, unexpected synergistic effects are obtained, and herbicidal activity is more remarkable than the sum of the expected activities using individual herbicides, and the activity of individual herbicides. The synergistic effect is manifested by a reduced application rate, a broader weed control spectrum, a faster and more durable herbicidal action, which are desirable in the practice of weed control. These new compositions are significantly superior to existing herbicides in terms of the characteristics described, achieving reduced use and being more environmentally friendly.

The synergistic weeding composition provided by the invention also has the following advantages:

(1) The composition of the invention is environment-friendly and is easy to degrade in the environment.

(2) The weeding composition disclosed by the invention is low in cost and convenient to use, and has great economic and social benefits in popularization and application.

All patents, patent applications, and publications mentioned or cited herein are hereby incorporated by reference in their entirety to the same extent as if each individual publication was specifically and individually indicated to be incorporated by reference.

Detailed Description

The following examples are not intended to limit the invention but are merely illustrative of how the invention may be practiced. For certain weeds, these examples showed particularly significant effectiveness. Examples are as follows:

a) Examples

1. Methyldisulfuron and prometryn (1+10) dispersible oil suspending agent

1% of mesosulfuron, 10% of prometryn, 5% of calcium dodecyl benzene sulfonate, 8% of cardanol polyoxyethylene ether, 3% of fatty alcohol polyoxyethylene ether, 2.5% of organic bentonite, 2% of fumed silica, 8% of 100# solvent oil and methyl oleate are used for supplementing

2. Mesosulfuron-cilexetil (1+10) dispersible oil suspension

1% of mesosulfuron, 10% of simetryn, 5% of calcium dodecyl benzene sulfonate, 10% of sorbitan fatty acid ester polyoxyethylene ether, 3% of castor oil polyoxyethylene ether, 2% of cardanol polyoxyethylene ether, 3% of organic bentonite, 3% of fumed silica, 6% of 100# solvent oil, 15% of dimethyl nylon acid and methyl oleate are used for supplementing

The dispersible oil suspending agent processing equipment comprises: mixing kettle, colloid mill, sand mill, shearing machine, etc.

The processing process of the dispersible oil suspending agent comprises the following steps: all materials are put into a mixing kettle, stirred and mixed, then the materials are subjected to a colloid mill, and finally enter a sand mill for three-stage sand milling, finally the materials are uniformly sheared in a shearing machine, and after the materials are tested to be qualified, the materials are transferred to a storage tank for filling.

B) Test of efficacy

Post-emergence stem and leaf spray treatment:

1) Test conditions

1.1 Test target)

Culturing weeds by a potting method, placing the weeds in a plastic nutrition pot with the diameter of 180 х mm in a enamel tray, arranging surface soil (4/5) which is collected from farmlands and air-dried and sieved in the tray, controlling the initial stage of soil humidity to be 20%, selecting weed seeds with full and uniform seeds, soaking the weed seeds in warm water at 25 ℃ for 6 hours, accelerating germination in a biochemical incubator (dark) at 28 ℃, uniformly placing the just-exposed weed seeds on the surface of the soil, and then covering the soil by 0.5-1cm according to the particle size of the seeds.

1.2 Culture conditions

The method is carried out in a controllable sunlight greenhouse, the temperature is 20-30 ℃, natural illumination is carried out, and the relative humidity is 57-72%. The soil type is loam, the organic matter content is 1.63%, the pH=7.1, the alkaline hydrolysis nitrogen content is 84.3mg/kg, the quick-acting phosphorus content is 38.5mg/kg, and the quick-acting potassium content is 82.1mg/kg.

1.3 Instrument and equipment

3WP-2000 type walking spray tower (Nanjing agricultural machinery institute of agricultural division); GA0 model ten-thousandth electronic balance (germany); ZDR2000 intelligent data logger (zengzhuze instruments limited); SPX intelligent biochemical incubator (Ningbo Jiangnan instruments factory).

2) Test design

2.1 Reagents)

The desired active ingredients are purchased from the reagent company or are synthetically prepared according to conventional methods. The raw materials are all diluted by using acetone as solvent and 0.1% of emulsifier Tween-80 aqueous solution, and the diluted materials are diluted at present.

2.2 Test treatment

2.2.1 Dose setting)

In determining the ratio or content of the active ingredient A and the active ingredient B, the main purpose of the formulation should be considered according to the action characteristics of the two medicaments, the toxicity thereof and the like. The study was based on the pre-test at the early stage, and the single use and the mixed use of A, B active ingredients are respectively shown in the table. Water without agent, with the same solvent and emulsifier was used as a blank.

2.2.2 Test repetition

Each treatment was repeated 4 times, 3 pots each, 20 seeds of weed seeds were sown per pot, 60 plants per treatment.

2.3 Processing mode)

2.3.1 Time and number of treatments

The test was performed 1 time. And (3) after 1.5-2 leaves of weeds are planted, 10 plants of weeds in each pot are maintained, 30 plants are maintained for each treatment, and then the weeds are continuously cultured until 2-3 branches are planted for treatment.

2.3.2 Device and method of administration

Uniformly placing the cultured test material in an area of 0.5m ² On the platform of (C) with 3WP-2000 type rowSpraying the stem leaves of the walking type spraying tower, wherein the spraying amount is calculated by 450 kg/hectare, and the spraying pressure is 0.3MPa. After all the liquid medicine is sprayed, the air valve is closed, the spraying tower door is opened after 30 seconds, and the nutrition pot is taken out. Then the air valve is opened, 50mL of clean water is sprayed, and the liquid spraying pipe is cleaned.

3) Test method

Potting method is adopted. Weed cultivation is 1.1), and is carried out by referring to herbicide as a rule of biological assay in pesticide room. The application method is 2.3.2), and stem and leaf treatment is adopted. After treatment, the cells are transferred into a greenhouse for routine cultivation.

4) Data investigation and statistical analysis

4.1 Investigation method)

The entire seedlings of surviving weeds were cut off along the soil surface with a blade by an absolute number survey method, and the fresh weight of weeds was weighed with an analytical balance. For weeds that have died, the fresh weight is zero.

4.2 Time and number of surveys

The investigation was performed 21 days after the treatment, 1 total.

4.3 Data statistics analysis

Calculating the theoretical fresh weight inhibition rate (E0=X+Y-X X Y/100) of each treatment mixed combination by using a Gowing method, and then comparing the calculated fresh weight inhibition rate with the measured inhibition rate (E), evaluating the combined action type of the mixed combination of the calculated fresh weight inhibition rate and the measured inhibition rate on weeds, wherein when the E-E0 value is more than 10 percent, the E-E0 value is less than-10 percent, the E-E value is antagonistic, and the E-E0 value is addition between-10 percent and 10 percent. And determining the optimal proportion according to the actual control effect, the characteristics of herbicide, the balance of the formula and other factors. Wherein X is fresh weight inhibition rate when the dosage of the active ingredient A is P; y is the fresh weight inhibition rate when the dosage of the active component B is Q.

The statistical results are shown in tables 1-2 below.

TABLE 1 evaluation of actual control and Combined Effect of Methyldisulfuron-methyl Mixed prometryn on Niu Fan strands

TABLE 2 evaluation of actual control and combined action of mesosulfuron-methyl on Niu Fan strands

C) Demonstration of field

The herbicidal compositions prepared in examples 1 to 2 above were used for effect tests in rape fields against ALS and PS II inhibitor herbicides, and weeds occurring in the fields were mainly: radix seu cortex Myrtilli, herba Cynanchi Stauntonii, herba Galii Teneri, herba Veronicae, etc.

The test method comprises the following steps:

stem and leaf treatment (F): when the grass weeds are in 4-5 leaf stage, the manual sprayer is added with water of 30 kg/667 m ² The stem and leaf spray is adopted for uniform spraying.

The specific test agents and dosages are detailed in Table 3, with a cell area of 20 square meters and each treatment repeated 3 times. The investigation and control effects 20 days after the application are shown in Table 3.

Exemplary field effects of the formulated compositions described in Table 3

Through a large number of experiments and researches, the composition is unexpectedly found that the composition is used for preventing and killing main gramineae weeds, broadleaf weeds and the like in rape fields with ALS (ALS) resistance and PS II inhibitor resistance herbicides, has a surprising and unexpected synergistic effect, is more remarkable in the synergistic effect under a low dosage, can reduce the dosage, reduces the pollution to the environment, reduces the agricultural cost through reasonable compounding, and has good application prospect. Meanwhile, the herbicide mixture has good selectivity and excellent synergistic effect on plants such as wheat fields, corn fields, paddy fields, peanuts, sugarcane, sorghum, millet, potatoes, soybeans, cotton, vegetables, bluegrass, festuca arundinacea, zoysia japonica and the like through tests, and can be developed into herbicide mixtures with wide market value.

Claims (10)

1. A herbicidal composition comprising mesosulfuron, characterized by comprising a herbicidally effective amount of active ingredient a and active ingredient B, wherein active ingredient a is mesosulfuron and active ingredient B is selected from one or two of the following compounds: prometryn or simetryn.

2. Herbicidal composition according to claim 1, characterized in that the weight ratio of a and B in the herbicidal composition is 1:100 to 30:1, preferably 1:80 to 10:1, more preferably 1:50 to 1:1, even more preferably 1:40 to 2:5.

3. Herbicidal composition according to claim 1, characterized in that the herbicidal composition comprises 1-95% by mass of a and B, preferably 10-80% by mass of the total amount.

4. The herbicidal composition of claim 1 further comprising a conventional adjuvant.

5. The herbicidal composition of claim 4 wherein the conventional adjuvants comprise carriers and/or surfactants.

6. The herbicidal composition of any one of claims 1 wherein the herbicidal composition further comprises at least one safener.

7. The herbicidal composition of claim 6 wherein the safener is selected from one or more of bisbenzoxazole acid, cyprosulfamide, pyraclostrobin, cloquintocet-mexyl, gibberellic acid, furilazole, metcamifen.

8. The herbicidal composition according to any one of claims 1 to 7, wherein the specific formulation of the herbicidal composition is a dispersible oil suspension, an aqueous suspension, a suspoemulsion, a wettable powder, an emulsifiable concentrate, a water dispersible granule, an aqueous emulsion or a microemulsion.

9. Use of a herbicidal composition according to any of claims 1 to 8 for controlling weeds, preferably in rape fields against ALS and against PS ii inhibitor herbicides.

10. A method of controlling unwanted vegetation, which comprises applying the herbicidal composition of any one of claims 1 to 8 to plants, plant parts, plant seeds or areas of vegetation, preferably the unwanted plants are weeds in oilseed rape fields which are resistant to ALS and to the PS ii inhibitor herbicides.