CN116783184A - 含有烷基-氧杂环烷基部分的氨磺酰基脲衍生物及其用途 - Google Patents
含有烷基-氧杂环烷基部分的氨磺酰基脲衍生物及其用途 Download PDFInfo
- Publication number
- CN116783184A CN116783184A CN202180074301.7A CN202180074301A CN116783184A CN 116783184 A CN116783184 A CN 116783184A CN 202180074301 A CN202180074301 A CN 202180074301A CN 116783184 A CN116783184 A CN 116783184A
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- China
- Prior art keywords
- compound
- disease
- compound according
- compounds
- pharmaceutical composition
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063074521P | 2020-09-04 | 2020-09-04 | |
| US63/074521 | 2020-09-04 | ||
| PCT/US2021/049001 WO2022051582A1 (en) | 2020-09-04 | 2021-09-03 | Sulphamoyl urea derivatives containing alkyl-oxacycloalkyl moiety and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116783184A true CN116783184A (zh) | 2023-09-19 |
Family
ID=77951864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180074301.7A Pending CN116783184A (zh) | 2020-09-04 | 2021-09-03 | 含有烷基-氧杂环烷基部分的氨磺酰基脲衍生物及其用途 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240043410A1 (https=) |
| EP (1) | EP4208459A1 (https=) |
| JP (1) | JP2023540733A (https=) |
| KR (1) | KR20230061505A (https=) |
| CN (1) | CN116783184A (https=) |
| AR (1) | AR123435A1 (https=) |
| AU (1) | AU2021336518A1 (https=) |
| BR (1) | BR112023003792A2 (https=) |
| CA (1) | CA3191410A1 (https=) |
| IL (1) | IL301055A (https=) |
| MX (1) | MX2023002686A (https=) |
| WO (1) | WO2022051582A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| PL3983387T3 (pl) | 2019-06-12 | 2024-08-19 | NodThera Limited | Pochodne sulfonylomocznika i ich zastosowania |
| WO2025104268A1 (en) | 2023-11-17 | 2025-05-22 | NodThera Limited | Forms of urea derivatives and related uses |
| WO2025104244A1 (en) * | 2023-11-17 | 2025-05-22 | NodThera Limited | Methods of preparing urea derivatives |
| WO2025153532A1 (en) * | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107428696A (zh) * | 2015-02-16 | 2017-12-01 | 昆士兰大学 | 磺酰脲和相关化合物及其用途 |
| WO2019121691A1 (en) * | 2017-12-18 | 2019-06-27 | NodThera Limited | Sulphonyl urea derivatives as nlrp3 inflammasome modulators |
| WO2020035464A1 (en) * | 2018-08-15 | 2020-02-20 | Inflazome Limited | Novel sulfonamideurea compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| PT1270565E (pt) | 1997-01-29 | 2004-09-30 | Pfizer | Furano-2-sulfonamida 4-substituida e sua utilizacao na preparacao de derivados de sulfonilureia |
| ES2988798T3 (es) | 2017-07-24 | 2024-11-21 | Novartis Ag | Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de NLRP |
-
2021
- 2021-09-03 IL IL301055A patent/IL301055A/en unknown
- 2021-09-03 JP JP2023514910A patent/JP2023540733A/ja active Pending
- 2021-09-03 KR KR1020237011396A patent/KR20230061505A/ko active Pending
- 2021-09-03 MX MX2023002686A patent/MX2023002686A/es unknown
- 2021-09-03 CA CA3191410A patent/CA3191410A1/en active Pending
- 2021-09-03 BR BR112023003792A patent/BR112023003792A2/pt unknown
- 2021-09-03 US US18/043,883 patent/US20240043410A1/en active Pending
- 2021-09-03 WO PCT/US2021/049001 patent/WO2022051582A1/en not_active Ceased
- 2021-09-03 CN CN202180074301.7A patent/CN116783184A/zh active Pending
- 2021-09-03 EP EP21778667.2A patent/EP4208459A1/en active Pending
- 2021-09-03 AU AU2021336518A patent/AU2021336518A1/en active Pending
- 2021-09-03 AR ARP210102472A patent/AR123435A1/es unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107428696A (zh) * | 2015-02-16 | 2017-12-01 | 昆士兰大学 | 磺酰脲和相关化合物及其用途 |
| WO2019121691A1 (en) * | 2017-12-18 | 2019-06-27 | NodThera Limited | Sulphonyl urea derivatives as nlrp3 inflammasome modulators |
| WO2020035464A1 (en) * | 2018-08-15 | 2020-02-20 | Inflazome Limited | Novel sulfonamideurea compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023540733A (ja) | 2023-09-26 |
| KR20230061505A (ko) | 2023-05-08 |
| WO2022051582A1 (en) | 2022-03-10 |
| MX2023002686A (es) | 2023-04-03 |
| IL301055A (en) | 2023-05-01 |
| AR123435A1 (es) | 2022-11-30 |
| EP4208459A1 (en) | 2023-07-12 |
| CA3191410A1 (en) | 2022-03-10 |
| US20240043410A1 (en) | 2024-02-08 |
| BR112023003792A2 (pt) | 2023-03-28 |
| AU2021336518A1 (en) | 2023-03-23 |
| TW202229265A (zh) | 2022-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |