CN116767732A

CN116767732A - Automatic change sample storage device

Info

Publication number: CN116767732A
Application number: CN202310844080.8A
Authority: CN
Inventors: 谢松华; 罗沉; 程义
Original assignee: Shanghai Huicheng Biomedical Technology Co ltd
Current assignee: Shanghai Huicheng Biomedical Technology Co ltd
Priority date: 2023-07-10
Filing date: 2023-07-10
Publication date: 2023-09-19

Abstract

The application discloses an automatic sample storage device, which comprises a butt joint receiving chamber, an operation cabin and a low-temperature storage cabin; an operation cabin is arranged above the low-temperature storage cabin, and can convey the transfer tank or the biological sample plate frame received by the butt joint receiving chamber into the low-temperature storage cabin; the nitrogen spraying pipe fitting and the grabbing component are arranged in the operation cabin; the grabbing component is arranged at a position corresponding to the butt joint receiving chamber, can grab the transfer tank or the biological sample plate, and the nitrogen spraying pipe fitting can spray nitrogen to the grabbing component. The biological plate rack and the biological sample tube of the transfer tank can be grabbed and sent to the first storage plate or the second storage plate by the grabbing component, and the first storage plate or the second storage plate is placed on a vacancy on the storage rack by the lifting piece.

Description

Automatic change sample storage device

Technical Field

The application relates to the technical field of biological medical treatment, in particular to an automatic sample storage device.

Background

In the biomedical field, sample cryopreservation apparatuses are used for storing biological samples of blood samples, vaccines, bacterial strains, etc. at low temperatures, and keeping the samples in liquid nitrogen for long-term active preservation. The device is provided with a plurality of sample boxes, a plurality of test tubes are arranged and stored in the sample boxes, and samples to be stored are in the test tubes.

In the existing freezing equipment, the whole sample box is stored and taken out, when individual test tubes need to be taken out, the sample box with the test tubes can only be taken out from the equipment, and the required test tubes can be taken out at room temperature, so that other unused samples in the sample box can be damaged. There are also individual storage devices that have a tube picking function to pick the desired tube from the cassette and place it in a target sample cassette that is specially used to place the tube that needs to be removed, so that the activity of other unused samples is not affected.

However, hospitals or research institutions and the like generally need to store a large amount of samples through a plurality of storage devices, and need to manually dock a plurality of storage devices, so that the problem of cell pollution caused by manual operation is easily caused, the docking efficiency of the samples is reduced, and meanwhile, the problem of whole-course cold chain in the sample transferring process cannot be completely guaranteed, so that an automatic sample storage device is urgently needed.

Disclosure of Invention

This section is intended to outline some aspects of embodiments of the application and to briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section as well as in the description of the application and in the title of the application, which may not be used to limit the scope of the application.

The present application has been made in view of the above-mentioned or existing problems occurring in the prior art.

Therefore, an object of the present application is to provide an automated sample storage apparatus capable of interfacing with a transfer mechanism, receiving a transfer pot from the transfer mechanism or transferring the transfer pot to the transfer mechanism, interfacing the transfer pot with an operation chamber through a jacking member, storing a biological sample through a storage pot, grasping a biological plate rack or a single-tube biological sample in the transfer pot or the storage pot through a grasping member, and cooling a plate rack gripper or a sample tube gripper by a nitrogen spraying tube, thereby completely realizing automation and operating the biological sample all under a cold chain member.

In order to solve the technical problems, the application provides the following technical scheme: an automated sample storage apparatus comprising a docking receiving chamber, an operating bay, and a cryogenic storage bay;

an operation cabin is arranged above the low-temperature storage cabin, and can convey the transfer tank or the biological sample plate frame received by the butt joint receiving chamber into the low-temperature storage cabin;

the nitrogen spraying pipe fitting and the grabbing component are arranged in the operation cabin; the grabbing component is arranged at a position corresponding to the butt joint receiving chamber, can grab the transfer tank or the biological sample plate, and the nitrogen spraying pipe fitting can spray nitrogen to the grabbing component.

As a preferred embodiment of the automated sample storage device of the application, wherein: the butt joint receiving room comprises a jacking receiving area, an operation cabin is correspondingly arranged above the jacking receiving area, and a receiving jacking mechanism is arranged below the jacking receiving area; the receiving jacking mechanism comprises a movable track piece and a jacking member; the movable track component can receive the transfer tank and transmit the transfer tank to the jacking component, and the jacking component can lift the transfer tank and dock with the operation cabin.

As a preferred embodiment of the automated sample storage device of the application, wherein: the movable track piece comprises a conveyor belt motor, a motor belt, a belt rotating wheel, a conveyor track, a track rotating shaft supporting plate and a track rotating shaft supporting frame;

the conveyer belt motor is connected with the belt runner through motor belt, and the belt runner sets up in the track pivot, and two sets of conveying tracks are connected respectively to the both sides of track pivot, and track pivot backup pad sets up in the centre of two sets of conveying tracks, and track pivot support frame supports the track pivot.

As a preferred embodiment of the automated sample storage device of the application, wherein: the jacking component comprises a jacking motor, a motor bottom plate, a guide post, a lifting plate, a lifting post, a guide post fixing plate, a transfer tank lifting plate, a screw rod,

the jacking motor is connected with the motor bottom plate, the guide post fixed plate is connected with the track pivot backup pad, the top of guide post fixed plate is provided with transfer jar lifter plate, the lead screw upper end is connected with the guide post fixed plate rotation, the lower extreme is connected with the jacking motor, the lifter plate sets up in the top of motor bottom plate and is connected with lead screw-thread fit, the upper end and the lower extreme of guide post are connected with guide post fixed plate and motor bottom plate respectively, the guide post upwards passes the guide post fixed plate and is connected with transfer jar lifter plate, the lifter post lower extreme is connected with the lifter plate.

As a preferred embodiment of the automated sample storage device of the application, wherein: the lifting plate is connected with the guide post in an up-down sliding way.

As a preferred embodiment of the automated sample storage device of the application, wherein: the height of the conveying crawler belt is higher than that of the crawler belt rotating shaft supporting plate.

As a preferred embodiment of the automated sample storage device of the application, wherein: the operation cabin further comprises a reference plate, a sealing door component and a tank cover passage opening, wherein the receiving door is arranged at the position of the reference plate corresponding to the butt joint receiving chamber, the sealing door component can seal the receiving door, and the tank cover passage opening can be closed by the tank cover lifting component.

As a preferred embodiment of the automated sample storage device of the application, wherein: the grabbing component comprises an X-axis guide rail, a Y-axis guide rail, an X-axis sliding frame, a plate frame Z-axis, a sampling tube Z-axis, plate frame clamping jaws, sampling tube clamping jaws, a plate frame Z-axis motor and a sampling tube Z-axis motor;

the Y-axis guide rail is arranged on the upper end face of the reference plate, the X-axis guide rail is in sliding connection with the Y-axis guide rail, the X-axis sliding frame is in sliding connection with the X-axis guide rail, the plate frame Z-axis motor can drive the plate frame Z-axis to be in sliding connection with the inner side of the X-axis sliding frame up and down, the plate frame Z-axis lower end face is connected with the plate frame clamping jaw, the plate frame clamping jaw can clamp a biological plate frame, the sample tube Z-axis motor can drive the sample tube Z-axis to be in sliding connection with the inner side of the X-axis sliding frame up and down, the lower end face of the sample tube Z-axis is connected with the sample tube clamping jaw, and the sample tube clamping jaw can grab a single-tube biological sample.

As a preferred embodiment of the automated sample storage device of the application, wherein: the lower end of the tank cover channel opening is provided with a nitrogen spraying pipe fitting which can spray nitrogen and cool the plate rack clamping jaw or the sampling pipe clamping jaw.

As a preferred embodiment of the automated sample storage device of the application, wherein: the tank cover lifting member comprises a tank cover Y shaft, a tank cover Z shaft supporting shaft, a tank cover Z shaft and a tank cover; the cover Y axle sets up the up end at the benchmark board, and cover Z axle back shaft and cover Y axle sliding connection, but cover Z axle and cover Z axle back shaft Z are to sliding connection, and the cover is connected with cover Z axle.

As a preferred embodiment of the automated sample storage device of the application, wherein: the tank cover can be inserted into the tank cover passage opening for sealing connection.

As a preferred embodiment of the automated sample storage device of the application, wherein: the sealing door component comprises a sealing door motor, a sealing door, a sealing motor shaft and a support; the support sets up the up end at the benchmark board, and sealing door motor is connected with sealed motor shaft, and the support supports the motor shaft, and sealing door motor passes through the motor shaft and drives sealing door and can seal the receiving door.

As a preferred embodiment of the automated sample storage device of the application, wherein: the low-temperature storage cabin comprises a storage tank, a storage rack top plate and lifting pieces;

the storage tank is internally provided with a storage rack, a storage rack top plate and a lifting piece, and the upper end of the storage rack is provided with the storage rack top plate.

As a preferred embodiment of the automated sample storage device of the application, wherein: a first storage groove, a second storage groove, a first storage plate and a second storage plate are arranged in the storage rack, and a lifting opening is formed in the storage rack; a lifting opening is arranged between the first storage tank and the second storage tank, and the first storage tank and the second storage tank can be used for respectively placing the first storage plate and the second storage plate.

As a preferred embodiment of the automated sample storage device of the application, wherein: the storage racks can be vertically arranged in multiple groups.

As a preferred embodiment of the automated sample storage device of the application, wherein: the lifting piece can lift up and down to rotate after lifting up the first storage plate or the second storage plate, and the lifting piece can lift up and down to rotate.

As a preferred embodiment of the automated sample storage device of the application, wherein: the display screen and the keyboard are arranged outside the operation cabin.

As a preferred embodiment of the automated sample storage device of the application, wherein: the storage tank further comprises a liquid nitrogen valve arranged on the outer side of the storage tank and a wheel set arranged on the bottom side of the storage tank.

The application has the beneficial effects that: according to the application, the middle tank conveyed from the transferring equipment can be received through the movable crawler, the lifting mechanism can drive the transferring tank to lift and butt the operation cavity, the grabbing component can grab the biological plate frame or the biological sample tube of the transferring tank and send the biological plate frame or the biological sample tube to the first storage plate or the second storage plate, and the first storage plate or the second storage plate is placed on a vacant site on the storage frame through the lifting piece.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the description of the embodiments will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art. Wherein:

FIG. 1 is an overall schematic of an automated specimen storage device.

FIG. 2 is a top view of a hidden housing of the automated specimen storage device.

Fig. 3 is a hidden housing isometric view of an automated sample storage device.

Fig. 4 is an isometric view of a jacking receiving area of an automated sample storage device.

Fig. 5 is an isometric view of a receiving jack mechanism of an automated sample storage device.

Fig. 6 is another schematic view of a receiving jacking mechanism of an automated specimen storage device.

Fig. 7 is a schematic perspective view of a can lid lifting member of an automated sample storage device.

Fig. 8 is a schematic perspective view of a storage rack of an automated specimen storage device.

Fig. 9 is a top view of a single storage rack of an automated specimen storage device.

FIG. 10 is a schematic perspective view of multiple sets of racks of an automated specimen storage device.

Fig. 11 is a schematic perspective view of a gripping member of an automated sample storage device.

FIG. 12 is an enlarged schematic view of the rack jaws of the automated sample storage device.

Fig. 13 is a schematic diagram of a first memory board of an automated sample storage device.

Fig. 14 is a schematic diagram of a second memory plate of the automated specimen storage device.

Fig. 15 is a schematic perspective view of a lift of an automated specimen storage device.

FIG. 16 is an exploded view of the lift of the automated specimen storage device.

Detailed Description

In order that the above-recited objects, features and advantages of the present application will become more readily apparent, a more particular description of the application will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings.

In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application, but the present application may be practiced in other ways other than those described herein, and persons skilled in the art will readily appreciate that the present application is not limited to the specific embodiments disclosed below.

Further, reference herein to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic can be included in at least one implementation of the application. The appearances of the phrase "in one embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments.

Example 1

Referring to fig. 1 to 2, an automated sample storage apparatus according to a first embodiment of the present application includes a docking chamber 1, an operation compartment 2, and a low-temperature storage compartment 3, wherein the docking chamber 1 can receive a transfer tank transferred from a transfer structure, and can lift and lower the transfer tank to dock with the operation compartment 2, and the low-temperature storage compartment 3 can store biological samples therein.

Specifically, the device comprises a butt joint receiving room 1, an operation cabin 2 and a low-temperature storage cabin 3;

an operation cabin 2 is arranged above the low-temperature storage cabin 3, and the operation cabin 2 can carry the transfer tank or the biological sample rack received by the docking receiving chamber 1 into the low-temperature storage cabin 3;

the nitrogen spraying pipe fitting 21 and the grabbing component 22 are arranged in the operation cabin 2; the grabbing component 22 is arranged at a position corresponding to the butt joint receiving chamber 1, and can grab the transfer tank or the biological sample plate, and the nitrogen spraying pipe fitting 21 can spray nitrogen to the grabbing component 22; the gripping member 22 may grip the biological rack or the biological sample tube in the transfer tank or the low-temperature storage compartment 3, and the nitrogen-spraying pipe 21 may spray nitrogen to the gripping member 22.

In summary, the transfer tank conveyed by the transfer structure can be received by the butt joint receiving chamber 1, the transfer tank is lifted and butted with the operation cabin 2, the biological sample grabbing component 22 can be stored in the low-temperature storage cabin 3, the biological plate frame or the biological sample tube in the transfer tank or the low-temperature storage cabin 3 can be clamped, the nitrogen spraying pipe fitting 21 can spray nitrogen to the grabbing component 22, and the biological plate frame and the biological sample tube can be stored in the low-temperature storage cabin 3.

Example 2

Referring to fig. 1 to 16, in a second embodiment of the present application, in the above embodiment, an automated sample storage apparatus includes a docking chamber 1, an operation compartment 2, and a low-temperature storage compartment 3, wherein the docking chamber 1 can receive a transfer tank transferred from a transfer structure, and can lift and dock the transfer tank with the operation compartment 2, and the low-temperature storage compartment 3 can store biological samples therein.

Further, the docking receiving chamber 1 comprises a jacking receiving area 11, the upper part of the jacking receiving area 11 corresponds to the operation cabin 2, and a jacking mechanism 12 is arranged below the jacking receiving area; the reception jacking mechanism 12 includes a moving track member 121 and a jacking member 122; the moving track 121 may receive the transfer pot and transfer it to the lifting member 122, where the lifting member 122 may lift and dock the transfer pot with the pod 2.

Further, the moving track member 121 includes a conveyor motor 12101, a motor belt 12102, a belt pulley 12103, a conveyor track 12104, a track shaft 12105, a track shaft support plate 12106, and a track shaft support frame 12107;

the conveyor belt motor 12101 is connected to the belt runner 12103 through a motor belt 12102, the belt runner 12103 is disposed on the track shaft 12105, two sets of conveyor tracks 12104 are respectively connected to both sides of the track shaft 12105, the track shaft support plate 12106 is disposed in the middle of the two sets of conveyor tracks 12104, and the track shaft support frame 12107 supports the track shaft 12105.

Preferably, the belt pulley 12103 is fixedly coupled to the track shaft 12105.

Preferably, the belt 12101 is rotated by the belt 12102 and the belt wheel 12103, the belt wheel 12103 drives the track shaft 12105 to rotate, the track shaft 12105 drives the conveyor track 12104 to rotate, and the conveyor track 12104 can drive the transfer pot to move.

Further, the jacking member 122 includes a jacking motor 12201, a motor base plate 12202, a guide column 12203, a lifting plate 12204, a lifting column 12205, a guide column fixing plate 12206, a transfer pot lifting plate 12207, a screw rod 12208,

jacking motor 12201 is connected with motor bottom plate 12202, guide post fixed plate 12206 and track pivot backup pad 12106 fixed connection, the top of guide post fixed plate 12206 is provided with transfer jar lifter plate 12207, the upper end of lead screw 12208 is rotated with guide post fixed plate 12206 and is connected, the lower extreme is connected with jacking motor 12201, lifter plate 12204 sets up in the top of motor bottom plate 12202 and is connected with lead screw 12208 screw-thread fit, the upper end and the lower extreme of guide post 12203 are connected with guide post fixed plate 12206 and motor bottom plate 12202 respectively, lifter post 12205 upwards passes guide post fixed plate 12206 and is connected with transfer jar lifter plate 12207, lifter post 12205 lower extreme is connected with lifter plate 12204.

Preferably, the upper end of the guide column 12203 is fixedly connected with the guide column fixing plate 12206, and the lower end is fixedly connected with the motor bottom plate 12202.

It should be noted that the reference numeral of the transfer tank is S1, the reference numeral of the bio-plate rack is S2, and the reference numeral of the single-tube biological sample is S3.

It should be noted that, the guide post fixing plate 12206 is not driven by the screw rod 12208 when rotating, only rotation can be performed between the screw rod 12208 and the guide post fixing plate 12206, the lifting plate 12204 is driven to lift by the screw rod 12208 when rotating, the lifting column 12205 is driven to lift by the lifting plate 12204, and the transfer pot lifting plate 12207 is driven to lift by the lifting column 12205.

It should be noted that, the track shaft supporting plate 12106 is provided with a notch, the transfer tank lifting plate 12207 is installed in the notch, the transfer track 12104 can transfer the transfer tank to the right upper end of the transfer tank lifting plate 12207, and then the transfer tank lifting plate 12207 is lifted to fix the bottom plate of the transfer tank to drive the transfer tank to lift continuously.

Preferably, the jacking motor 12201 starts to rotate, drives the lead screw 12208 to rotate, the lead screw 12208 drives the lifting plate 12204 to lift, the lifting plate 12204 drives the lifting column 12205 to lift, the lifting column 12205 drives the transfer tank lifting plate 12207 to lift, and the transfer tank lifting plate 12207 is clamped with the transfer tank bottom plate on the conveying crawler 12104 in the lifting process, so as to continuously drive the transfer tank to lift.

Further, the lifting plate 12204 is slidably connected to the guide column 12203 up and down.

Further, the height of the conveyor belt 12104 is higher than the height of the belt shaft support plate 12106.

Preferably, the height of the conveyor belt 12104 is higher than the height of the belt shaft support plate 12106 in order to facilitate the transfer pot to smoothly reach directly above the transfer pot lifting plate 12207.

It should be noted that, the width of the transfer pot lifting plate 12207 is smaller than the width between the two sets of conveyor tracks 12104, so that the transfer pot lifting plate 12207 can be lifted smoothly and the transfer pot can be lifted smoothly.

Further, the operation cabin 2 further comprises a reference plate 23, a sealing door member 24, a tank cover passage opening 25 and a tank cover lifting member 26, wherein a receiving door 27 is arranged at a position of the reference plate 23 corresponding to the butt receiving chamber 1, the sealing door member 24 can seal the receiving door 27, and the tank cover lifting member 26 can close the tank cover passage opening 25.

Further, the grasping member 22 includes an X-axis guide rail 2201, a y-axis guide rail 2202, an X-axis carriage 2203, a rack Z-axis 2204, a cuvette Z-axis 2205, a rack jaw 2206, a cuvette jaw 2207, a rack Z-axis motor 2208, a cuvette Z-axis motor 2209;

y-axis guide rail 2202 is arranged on the upper end face of reference plate 23, X-axis guide rail 2201 is slidably connected with Y-axis guide rail 2202, X-axis sliding frame 2203 is slidably connected with X-axis guide rail 2201, plate frame Z-axis motor 2208 can drive plate frame Z-axis 2204 to be vertically slidably connected along the inner side of X-axis sliding frame 2203, the lower end face of plate frame Z-axis 2204 is connected with plate frame clamping jaw 2206, plate frame clamping jaw 2206 can clamp biological plate frame, sample tube Z-axis motor 2209 can drive sample tube Z-axis 2205 to be vertically slidably connected along the inner side of X-axis sliding frame 2203, the lower end face of sample tube Z-axis 2205 is connected with sample tube clamping jaw 2207, and sample tube clamping jaw 2207 can grab single-tube biological samples.

Preferably, the rack Z-axis motor 2208 can drive the rack Z-axis 2204 to be connected in a sliding manner up and down along the inner side of the X-axis sliding frame 2203, a straight toothed plate is arranged on the side face of the rack Z-axis 2204, the rack Z-axis motor 2208 drives a gear to rotate, the gear is matched with the straight toothed plate to achieve lifting, the side face of the sample tube Z-axis motor 2209 is also provided with the straight toothed plate, the lower end face of the rack Z-axis 2204 is connected with the rack clamping jaw 2206, the rack clamping jaw 2206 can clamp a biological rack, the sample tube Z-axis motor 2209 can drive the sample tube Z-axis 2205 to be connected in a sliding manner up and down along the inner side of the X-axis sliding frame 2203, the lower end face of the sample tube Z-axis 2205 is connected with the sample tube clamping jaw 2207, the rack clamping jaw motor can drive the board clamping jaw 2206 to clamp the rack, and the sample tube clamping jaw 2207 can clamp the single tube biological sample tube.

Preferably, after the transfer pot is docked with the receiving door 27, the gripping member 22 is moved to the upper side of the transfer pot, and the upper cover of the transfer pot is removed and placed to one side;

note that the cuvette holding jaw 2207 or the rack holding jaw 2206 can be moved in XYZ axes as needed.

Preferably, the X-axis guide rail 2201 can move along the Y-axis guide rail 2202, the X-axis sliding frame 2203 can slide on the X-axis guide rail 2201, the X-axis sliding frame 2203 can drive the plate frame Z-axis 2204 and the sample tube Z-axis 2205 to slide, the plate frame Z-axis 2204 and the sample tube Z-axis 2205 slide above the transfer tank to clamp the plate frame or the biological sample tube inside the transfer tank, the clamped plate frame or the biological sample tube can be carried to the tank cover channel opening 25, and the nitrogen spraying pipe fitting 21 can spray nitrogen to the plate frame clamping jaw 2206 or the sample tube clamping jaw 2207 for cooling.

Further, the lower end of the tank cover channel opening 25 is provided with a nitrogen spraying pipe fitting 21, and the nitrogen spraying pipe fitting 21 can spray nitrogen to cool the plate rack clamping jaw 2206 or the sampling pipe clamping jaw 2207.

Further, the can lid lifting member 26 includes a can lid Y axis 2601, a can lid Z axis support axis 2602, a can lid Z axis 2603, and a can lid 2604; the can lid Y axis 2601 is provided on the upper end surface of the reference plate 23, the can lid Z axis support axis 2602 is slidably connected to the can lid Y axis 2601, the can lid Z axis 2603 is slidably connected to the can lid Z axis support axis 2602 in the Z direction, and the can lid 2604 is connected to the can lid Z axis 2603.

Preferably, before the rack clamping jaw 2206 or the sampling tube clamping jaw 2207 drive the biological rack or the single-tube biological sample to reach the tank cover channel opening 25, the tank cover 2604 in the tank cover channel opening 25 is opened in advance and moved aside, so that the grabbing component 22 is not influenced to work.

Preferably, the can cover 2604 is driven to slide upwards along the can cover Z-axis support shaft 2602 by the can cover Z-axis 2603, the can cover 2604 is separated from the can cover channel opening 25, and then the can cover Z-axis support shaft 2602 drives the can cover Z-axis 2603 and the can cover 2604 to slide along the can cover Y-axis 2601, so that the movement of the can cover 2604 aside does not affect the operation of the gripping member 22.

Further, the can lid 2604 may be inserted into the can lid access opening 25 for sealing connection.

Further, the seal door member 24 includes a seal door motor 2401, a seal door 2402, a seal motor shaft 2403, a mount 2404; the support 2404 is disposed on the upper end surface of the reference plate 23, the seal door motor 2401 is connected with the seal motor shaft 2403, the support 2404 supports the motor shaft 2403, and the seal door motor 2401 drives the seal door 2402 through the motor shaft 2403 to seal the receiving door 27.

It should be noted that, when the transfer tank lifting plate 12207 drives the transfer tank to lift, the sealing door motor 2401 drives the sealing door 2402 through the motor shaft 2403 to open the receiving door 27, then the transfer tank is docked with the receiving door 27, then the grabbing member 22 is moved above the transfer tank, and the upper cover of the transfer tank is clamped down and placed to one side.

Further, the low-temperature storage compartment 3 includes a storage tank 31, a storage rack 32, a storage rack top plate 33, and a lifting piece 34;

a storage rack 32, a storage rack top plate 33 and a lifting piece 34 are arranged in the storage tank 31, and the storage rack top plate 33 is arranged at the upper end of the storage rack 32.

It should be noted that, the top plate of the storage rack top plate 33 is provided with an access opening, the position of the access opening is set at a position corresponding to the tank cover channel opening 25, two temporary storage tanks for the rack are also provided at two sides of the access opening, the two temporary storage tanks for the rack can be used for placing the rack, the rack clamping jaw 2206 is convenient for temporarily placing the rack into the storage tank, and the pipe clamping jaw 2207 can perform pipe picking operation; the lifting member 34 will lift the empty first storage plate 3203 or second storage plate 3204 from the storage shelf 32 into the access opening; the first storage plate 3203 can accommodate 3 groups of biological plate frames, the second storage plate 3204 can accommodate multiple groups of sample tubes, the biological plate frames clamped by the plate frame clamping jaws 2206 can be placed into the first storage plate 3203, the tube clamping jaws 2207 can perform tube picking operation, and the tube clamping jaws 2207 can place single-tube sample tubes into the second storage plate 3204.

Further, a first storage groove 3201, a second storage groove 3202, a first storage plate 3203, a second storage plate 3204 and a lifting opening 3205 are arranged in the storage rack 32; a lifting opening 3205 is provided between the first storage groove 3201 and the second storage groove 3202, and the first storage groove 3201 and the second storage groove 3202 may respectively place a first storage plate 3203 and a second storage plate 3204.

It should be noted that, the storage tank 31 is fixedly connected to the tank cover channel opening 25, the first storage plate 3203 may be used to place a biological plate rack, and the second storage plate 3204 may be used to place multiple groups of single-tube samples.

It should be noted that the storage rack 32 is provided with four sets of first storage tanks 3201, second storage tanks 3202 and lifting ports 3205 arranged in a circumferential array, and the lifting ports 3205 serve the first storage tanks 3201 and the second storage tanks 3202.

It should be noted that the storage racks 32 are vertically arranged in a plurality of groups, so that a transverse channel can be formed between the upper and lower storage racks 32, and a plurality of groups of vertical lifting openings 3205 form vertical channels.

It should be noted that, the lifting element 34 is composed of a lifting plate S4, a central shaft S5 and a rotating shaft S6, the lifting plate S4 can slide up and down along a notch formed on the side surface of the central shaft S5, the rotating shaft S6 can drive the lifting plate S4 and the central shaft S5 to rotate, so that the lifting plate S4 can rotate along a transverse channel and move up and down along a vertical channel; the lifting piece 34 is provided at the center of the storage rack 32, and is operated to lift and rotate by the motor-driven lifting plate S4.

Further, the storage shelves 32 may be vertically arranged in multiple groups.

Further, the lifting element 34 can lift up and down the first storage plate 3203 or the second storage plate 3204, and lift up the first storage plate 3203 or the second storage plate 3204 to the access opening to cooperate with the gripping member 22, so as to access the biological plate rack or the biological sample plate tube, and the lifting element 34 can be lifted and rotated.

Further, the device also comprises a display screen 4 and a keyboard 5 which are arranged outside the operation cabin 2.

Further, the device also comprises a liquid nitrogen valve 35 arranged outside the storage tank 31, and a wheel set 36 arranged at the bottom side of the storage tank 31.

Preferably, the program of the whole system can be controlled through the display screen 4 and the keyboard 5, and commands are issued, the total amount of liquid nitrogen in the storage tank 31 can be controlled through the liquid nitrogen valve 35, and the wheel set can facilitate the movement of the device.

In summary, the application can receive the transfer can transferred by the transfer device by moving the crawler 121, and transfer the transfer can to the right above the transfer can lifting plate 12207, the transfer can is driven by the lifting member 122 to butt against the operation cabin 2, the sealing door motor 2401 drives the sealing door 2402 to open the receiving door 27 by the motor shaft 2403 while the transfer can is lifted, after the transfer can is butt against the operation cabin 2, the grabbing member 22 moves along the XY axis, the upper cover of the transfer can is opened to one side right above the transfer can, then the plate rack clamping jaw 2206 or the sampling tube clamping jaw 2207 moves along the Z axis, the biological plate rack or the single-tube biological sample in the transfer can is clamped and moved to the position of the tank cover passage opening 25, the tank cover lifting member 26 opens the tank cover 2604 in advance and is far away from the tank cover passage opening 25, the plate rack clamping jaw 2206 or the sampling tube clamping jaw 2207 drives the biological plate rack or the single-tube biological sample to move in the Z-axis direction and enter the tank cover channel opening 25, at this time, the nitrogen spraying pipe fitting 21 sprays nitrogen to cool the plate rack clamping jaw 2206 or the sampling tube clamping jaw 2207, meanwhile, the lifting piece 34 lifts the first storage plate 3203 or the second storage plate 3204 in the storage rack 32 to the access opening, namely, the lower part of the tank cover channel opening 25, the plate rack clamping jaw 2206 or the sampling tube clamping jaw 2207 can put the biological sample plate rack or the single-tube biological sample into the first storage plate 3203 or the second storage plate 3204 respectively, the process of storing the sample is completed, the lifting piece 34 can put the first storage plate 3203 or the second storage plate 3204 to the hollow position of the storage rack 32, the process of storing the sample is completed, and the principle of the process of the sampling sample is the same.

It is important to note that the construction and arrangement of the application as shown in the various exemplary embodiments is illustrative only. Although only a few embodiments have been described in detail in this disclosure, those skilled in the art who review this disclosure will readily appreciate that many modifications are possible (e.g., variations in sizes, dimensions, structures, shapes and proportions of the various elements, values of parameters (e.g., temperature, pressure, etc.), mounting arrangements, use of materials, colors, orientations, etc.) without materially departing from the novel teachings and advantages of the subject matter described in this application. For example, elements shown as integrally formed may be constructed of multiple parts or elements, the position of elements may be reversed or otherwise varied, and the nature or number of discrete elements or positions may be altered or varied. Accordingly, all such modifications are intended to be included within the scope of present application. The order or sequence of any process or method steps may be varied or re-sequenced according to alternative embodiments. In the claims, any means-plus-function clause is intended to cover the structures described herein as performing the recited function and not only structural equivalents but also equivalent structures. Other substitutions, modifications, changes and omissions may be made in the design, operating conditions and arrangement of the exemplary embodiments without departing from the scope of the present applications. Therefore, the application is not limited to the specific embodiments, but extends to various modifications that nevertheless fall within the scope of the appended claims.

Furthermore, in order to provide a concise description of the exemplary embodiments, all features of an actual implementation may not be described (i.e., those not associated with the best mode presently contemplated for carrying out the application, or those not associated with practicing the application).

It should be appreciated that in the development of any such actual implementation, as in any engineering or design project, numerous implementation-specific decisions may be made. Such a development effort might be complex and time consuming, but would nevertheless be a routine undertaking of design, fabrication, and manufacture for those of ordinary skill having the benefit of this disclosure.

It should be noted that the above embodiments are only for illustrating the technical solution of the present application and not for limiting the same, and although the present application has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the technical solution of the present application may be modified or substituted without departing from the spirit and scope of the technical solution of the present application, which is intended to be covered in the scope of the claims of the present application.

Claims

1. An automated specimen storage device, characterized by: comprises a butt joint receiving room (1), an operation cabin (2) and a low-temperature storage cabin (3);

the operation cabin (2) is arranged above the low-temperature storage cabin (3), and the operation cabin (2) can convey a transfer tank or a biological sample plate frame received by the butt receiving chamber (1) into the low-temperature storage cabin (3);

a nitrogen spraying pipe fitting (21) and a grabbing component (22) are arranged in the operation cabin (2); the grabbing component (22) is arranged at a position corresponding to the butt joint receiving chamber (1), the transfer tank or the biological sample plate can be grabbed, and the nitrogen spraying pipe fitting (21) can spray nitrogen to the grabbing component (22).

2. The automated specimen storage device of claim 1, wherein: the butt joint receiving room (1) comprises a jacking receiving area (11), the upper part of the jacking receiving area (11) corresponds to the operation cabin (2), and a receiving jacking mechanism (12) is arranged below the jacking receiving area; the receiving jacking mechanism (12) comprises a movable track member (121) and a jacking member (122); the movable crawler (121) can receive the transfer pot and transfer the transfer pot to the jacking member (122), and the jacking member (122) can lift the transfer pot and dock the transfer pot with the operation cabin (2).

3. The automated specimen storage device of claim 2, wherein: the movable track component (121) comprises a conveyor belt motor (12101), a motor belt (12102), a belt rotating wheel (12103), a conveyor track (12104), a track rotating shaft (12105), a track rotating shaft supporting plate (12106) and a track rotating shaft supporting frame (12107);

the conveyor belt motor (12101) is connected with the belt rotating wheel (12103) through a motor belt (12102), the belt rotating wheel (12103) is arranged on the track rotating shaft (12105), two groups of conveyor tracks (12104) are respectively connected to two sides of the track rotating shaft (12105), the track rotating shaft supporting plate (12106) is arranged in the middle of the two groups of conveyor tracks (12104), and the track rotating shaft supporting frame (12107) supports the track rotating shaft (12105).

4. An automated sample storage device according to claim 3, wherein: the jacking component (122) comprises a jacking motor (12201), a motor bottom plate (12202), a guide column (12203), a lifting plate (12204), a lifting column (12205), a guide column fixing plate (12206), a transfer tank lifting plate (12207), a screw rod (12208),

jacking motor (12201) with motor bottom plate (12202) are connected, guide post fixed plate (12206) with track pivot backup pad (12106) are connected, the top of guide post fixed plate (12206) is provided with transfer jar lifter plate (12207), lead screw (12208) upper end with guide post fixed plate (12206) rotate to be connected, the lower extreme with jacking motor (12201) are connected, lifter plate (12204) set up in motor bottom plate (12202) top and with lead screw (12208) screw-thread fit connection, the upper end and the lower extreme of guide post (12203) respectively with guide post fixed plate (12206) and motor bottom plate (12202) are connected, lift post (12205) upwards pass guide post fixed plate (12206) and transfer jar lifter plate (12207) are connected, lift post (12205) lower extreme with lifter plate (12204) are connected.

5. The automated specimen storage device of claim 4, wherein: the lifting plate (12204) is connected with the guide column (12203) in an up-and-down sliding way.

6. The automated specimen storage device of claim 5, wherein: the height of the conveyor track (12104) is higher than the height of the track shaft support plate (12106).

7. The automated specimen storage device of claim 1, wherein: the operation cabin (2) further comprises a reference plate (23), a sealing door component (24), a tank cover passage opening (25) and a tank cover lifting component (26), wherein a receiving door (27) is arranged at a position, corresponding to the butt joint receiving chamber (1), of the reference plate (23), the sealing door component (24) can seal the receiving door (27), and the tank cover lifting component (26) can close the tank cover passage opening (25).

8. The automated specimen storage device of claim 7, wherein: the grabbing component (22) comprises an X-axis guide rail (2201), a Y-axis guide rail (2202), an X-axis sliding frame (2203), a plate frame Z-axis (2204), a sample tube Z-axis (2205), plate frame clamping jaws (2206), sample tube clamping jaws (2207), a plate frame Z-axis motor (2208) and a sample tube Z-axis motor (2209);

y axle guide rail (2202) set up the up end of benchmark board (23), X axle guide rail (2201) with but Y axle guide rail (2202) sliding connection, X axle carriage (2203) with but X axle guide rail (2201) sliding connection, grillage Z axle motor (2208) can drive grillage Z axle (2204) along X axle carriage (2203) inboard sliding connection from top to bottom, grillage Z axle (2204) lower terminal surface connection grillage clamping jaw (2206), grillage clamping jaw (2206) can press from both sides the biological grillage and get, but sample tube Z axle motor (2209) can drive sample tube Z axle (2205) along X axle carriage (2203) inboard sliding connection from top to bottom, sample tube (2207) are connected to the lower terminal surface of sample tube Z axle (2205), single tube clamping jaw (2207) can snatch the biological sample of single tube.

9. The automated specimen storage device of claim 8, wherein: the lower end of the tank cover channel opening (25) is provided with a nitrogen spraying pipe fitting (21), and the nitrogen spraying pipe fitting (21) can spray nitrogen and cool down the plate frame clamping jaw (2206) or the sampling pipe clamping jaw (2207).

10. The automated specimen storage device of claim 9, wherein: the tank cover lifting member (26) comprises a tank cover Y-axis (2601), a tank cover Z-axis supporting shaft (2602), a tank cover Z-axis (2603) and a tank cover (2604); the tank cover Y-axis (2601) is arranged on the upper end face of the reference plate (23), the tank cover Z-axis supporting shaft (2602) is in sliding connection with the tank cover Y-axis (2601), the tank cover Z-axis (2603) is in Z-direction sliding connection with the tank cover Z-axis supporting shaft (2602), and the tank cover (2604) is connected with the tank cover Z-axis (2603).

11. The automated specimen storage device of claim 10, wherein: the can cover (2604) can be inserted into the can cover passage opening (25) for sealing connection.

12. The automated specimen storage device of claim 11, wherein: the sealing door member (24) comprises a sealing door motor (2401), a sealing door (2402), a sealing motor shaft (2403) and a support (2404); the support (2404) is arranged on the upper end face of the reference plate (23), the sealing door motor (2401) is connected with the sealing motor shaft (2403), the support (2404) supports the motor shaft (2403), and the sealing door motor (2401) drives the sealing door (2402) through the motor shaft (2403) to seal the receiving door (27).

13. The automated specimen storage device of claim 1, wherein: the low-temperature storage cabin (3) comprises a storage tank (31), a storage rack (32), a storage rack top plate (33) and a lifting piece (34);

the storage tank is characterized in that a storage frame (32), a storage frame top plate (33) and a lifting piece (34) are arranged in the storage tank (31), and the storage frame top plate (33) is arranged at the upper end of the storage frame (32).

14. The automated specimen storage device of claim 13, wherein: a first storage groove (3201), a second storage groove (3202), a first storage plate (3203) and a second storage plate (3204) are arranged in the storage frame (32), and a lifting opening (3205) is formed; lifting ports (3205) are formed in the middle of the first storage groove (3201) and the second storage groove (3202), and the first storage groove (3201) and the second storage groove (3202) can be used for placing the first storage plate (3203) and the second storage plate (3204) respectively.

15. The automated specimen storage device of claim 14, wherein: the storage racks (32) may be vertically arranged in multiple groups.

16. The automated specimen storage device of claim 15, wherein: the lifting piece (34) can lift and rotate after lifting the first storage plate (3203) or the second storage plate (3204), and the lifting piece (34) can lift and rotate.

17. The automated specimen storage device of claim 16, wherein: the device also comprises a display screen (4) and a keyboard (5) which are arranged on the outer side of the operation cabin (2).

18. The automated specimen storage device of claim 17, wherein: the device also comprises a liquid nitrogen valve (35) arranged on the outer side of the storage tank (31), and a wheel set (36) arranged on the bottom side of the storage tank (31).