CN116746917B - Jaundice tester calibrating device - Google Patents

Jaundice tester calibrating device Download PDF

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Publication number
CN116746917B
CN116746917B CN202310593437.XA CN202310593437A CN116746917B CN 116746917 B CN116746917 B CN 116746917B CN 202310593437 A CN202310593437 A CN 202310593437A CN 116746917 B CN116746917 B CN 116746917B
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China
Prior art keywords
light
jaundice
output
reflected light
reflected
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CN116746917A (en
Inventor
易辉
刘娟
钟文豪
沈锋林
李子楷
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Shenzhen Jumper Medical Equipment Co Ltd
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Shenzhen Jumper Medical Equipment Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02Operational features
    • A61B2560/0223Operational features of calibration, e.g. protocols for calibrating sensors
    • A61B2560/0228Operational features of calibration, e.g. protocols for calibrating sensors using calibration standards
    • A61B2560/0233Optical standards

Abstract

The application discloses jaundice tester calibrating device belongs to the medical instrument field. In the application, the light beam processing module in the jaundice tester calibration device can obtain two paths of incident light based on the output light beam of the jaundice tester, and convert the two paths of incident light into electric signals. The electric signal processing module can determine the light intensity of two paths of reflected light based on the preset bilirubin concentration value and the electric signal obtained by converting the two paths of incident light, and then the control light emitting module outputs a simulated reflected light beam to the jaundice tester based on the light intensity of the two paths of reflected light, so that the jaundice tester can measure a bilirubin concentration value based on the simulated reflected light beam, and further the bilirubin concentration value is compared with the preset bilirubin concentration value to calibrate. Therefore, the calibration device provided by the embodiment of the application does not need to use a standard color card, can be suitable for jaundice testers produced by different manufacturers, and is more convenient and wider in applicability.

Description

Jaundice tester calibrating device
Technical Field
The application belongs to the field of medical equipment, and particularly relates to a jaundice tester calibrating device.
Background
Neonatal jaundice is one of the common diseases of newborns, and the main cause of neonatal jaundice is that the amount of bilirubin metabolized by red blood cells is larger than the excretion amount, resulting in an increase in the in vivo bilirubin concentration. Jaundice testers are instruments used to measure bilirubin concentration values in neonates. Generally, a jaundice tester can also be called a percutaneous jaundice tester, and the measurement accuracy of the jaundice tester plays a vital role in discovering and timely treating jaundice.
In order to ensure the accuracy of the jaundice tester, currently, before the jaundice tester is used, the jaundice tester can be calibrated by using a standard color card provided by a manufacturer of the jaundice tester. However, the manufacturing process of the standard color card is complicated, and the color difference of the standard color card provided by different manufacturers is relatively large, so that the standard color card is difficult to interchange and use.
Disclosure of Invention
The application provides a jaundice tester calibrating device, this calibrating device need not to adopt standard color card to calibrate, and is more convenient and application scope wider.
A first aspect of an embodiment of the present application provides a jaundice tester calibration device, including a light beam processing module, an electrical signal processing module, and a light emitting module; the light beam processing module is used for obtaining first incident light and second incident light based on an output light beam of the jaundice tester, converting the first incident light into a first electric signal and converting the second incident light into a second electric signal; the electric signal processing module is used for determining the light intensity of the first reflected light and the light intensity of the second reflected light based on a preset bilirubin concentration value, the first electric signal and the second electric signal; the light emitting module is used for outputting a reflected light beam to the jaundice tester based on the light intensity of the first reflected light and the light intensity of the second reflected light, so that the jaundice tester can calibrate based on the reflected light beam.
In the jaundice tester calibration device provided by the embodiment of the application, the light beam processing module can obtain two incident lights based on the output light beam of the jaundice tester, and convert the two incident lights into electrical signals. The electric signal processing module can determine the light intensity of two reflected lights based on the preset bilirubin concentration value and the electric signal obtained by converting the two incident lights, and then the control light emitting module outputs a simulated reflected light beam to the jaundice tester based on the light intensity of the two reflected lights, so that the jaundice tester can measure a bilirubin concentration value based on the simulated reflected light beam, and further the bilirubin concentration value is compared with the preset bilirubin concentration value to calibrate. Therefore, the calibration device provided by the embodiment of the application does not need to use a standard color card, can be suitable for jaundice testers produced by different manufacturers, and is more convenient and wider in applicability.
Optionally, the beam processing module includes a beam splitter, a first optical filter, a second optical filter, a first photoelectric conversion unit, and a second photoelectric conversion unit; when the output light beam of the jaundice tester is natural light, the spectroscope is used for dividing the output light beam into a first incident light and a second incident light; the first optical filter is used for enabling light of a blue light wave band in the first incident light to pass through and blocking light outside the blue light wave band, and the second optical filter is used for enabling light of a green light wave band in the second incident light to pass through and blocking light outside the green light wave band; the first photoelectric conversion unit is configured to convert first incident light passing through the first optical filter into a first electrical signal, and the second photoelectric conversion unit is configured to convert second incident light passing through the second optical filter into a second electrical signal.
Optionally, when the output beam of the jaundice tester includes blue light and green light, the spectroscope is configured to reflect the blue light to obtain the first incident light, transmit the green light to obtain the second incident light, and the blue light and the green light are output by the jaundice tester in a time-sharing manner.
Therefore, the jaundice tester calibration device can be used for calibrating the jaundice tester adopting the natural light source and also can be used for calibrating the jaundice tester adopting the blue-green double-color light source, and the optical device and the electronic device are adopted to simulate the emission light beam without adopting a standard color card, so that the calibration device is suitable for calibrating the jaundice testers of different batches manufactured by different manufacturers, and has wide application range.
Optionally, the light beam processing module further includes a first attenuation sheet and a second attenuation sheet, where the first attenuation sheet is located between the beam splitter and the first photoelectric conversion unit, and the second attenuation sheet is located between the beam splitter and the second photoelectric conversion unit; the first attenuation sheet is used for adjusting the light intensity of the first incident light, and the second attenuation sheet is used for adjusting the light intensity of the second incident light.
In the application, the light intensity of the incident light is reduced by the attenuation sheet and then the incident light is input into the photoelectric conversion unit, so that the occurrence probability of the condition that the light intensity of the incident light exceeds the maximum acceptable light intensity of the photoelectric conversion unit can be reduced.
Optionally, the first electrical signal and the second electrical signal are analog signals, and the electrical signal processing module includes a first analog-to-digital converter, a second analog-to-digital converter, and a processing unit; the first analog-to-digital converter is used for converting the first electric signal into a first digital signal, and the second analog-to-digital converter is used for converting the second electric signal into a second digital signal; the processing unit is used for acquiring preset output light intensity of blue light and preset output light intensity of green light of the jaundice tester, and determining the light intensity of the first reflected light and the light intensity of the second reflected light based on the first digital signal, the second digital signal, the preset output light intensity of the blue light, the preset output light intensity of the green light and the preset bilirubin concentration value.
Optionally, the electric signal processing module further includes a first filter and a second filter, an output end of the first filter is connected with an input end of the first analog-to-digital converter, and an output end of the second filter is connected with an input end of the second analog-to-digital converter; the first filter is used for filtering noise signals in the first electric signal, and the second filter is used for filtering noise signals in the second electric signal.
In the method, the accuracy of the light intensity of the reflected light which is determined based on the digital signal can be effectively improved by filtering the noise signal in the electric signal through the filter.
Optionally, the electric signal processing module further includes a first operational amplifier and a second operational amplifier, wherein an output end of the first operational amplifier is connected with an input end of the first filter, and an output end of the second operational amplifier is connected with an input end of the second filter; the first operational amplifier is used for amplifying the first electric signal, and the second operational amplifier is used for amplifying the second electric signal.
In the application, before filtering noise signals in the electric signals, the electric signals can be amplified through the operational amplifier, so that the noise signals in the amplified electric signals are amplified, the filter can better filter the noise signals in the electric signals, and after the electric signals are amplified, the difficulty of the processing unit in determining the light intensity of the reflected light based on the digital signals can be reduced.
Optionally, the light emitting module includes a first driving unit, a second driving unit, a first light emitting unit, and a second light emitting unit; the first driving unit is used for driving the first light emitting unit to output first reflected light based on the light intensity of the first reflected light, and the first reflected light is blue light; the second driving unit is used for driving the second light emitting unit to output second reflected light based on the light intensity of the second reflected light, and the second reflected light is green light.
Optionally, the light emitting module further comprises a beam combiner; when the output light beam of the jaundice tester is natural light, the beam combiner is used for combining the first reflected light beam and the second reflected light beam into a reflected light beam, and outputting the reflected light beam to the jaundice tester.
Optionally, when the light beam output by the jaundice tester includes blue light and green light, the beam combiner is configured to transmit the first reflected light and the second reflected light to the jaundice tester, respectively.
A second aspect of the embodiments of the present application provides a method for calibrating a jaundice tester, which is applied to a device for calibrating a jaundice tester provided in the first aspect, and the method includes: the light beam processing module obtains first incident light and second incident light based on an output light beam of the jaundice tester, converts the first incident light into a first electric signal, and converts the second incident light into a second electric signal; the electric signal processing module determines the light intensity of the first reflected light and the light intensity of the second reflected light based on a preset bilirubin concentration value, the first electric signal and the second electric signal; the light emitting module outputs a reflected light beam to the jaundice tester based on the light intensity of the first reflected light and the light intensity of the second reflected light, so that the jaundice tester performs calibration based on the reflected light beam.
Optionally, the beam processing module includes a beam splitter, a first optical filter, a second optical filter, a first photoelectric conversion unit, and a second photoelectric conversion unit; the light beam processing module obtains a first incident light and a second incident light based on an output light beam of the jaundice tester, converts the first incident light into a first electric signal, and converts the second incident light into a second electric signal, and comprises: when the output light beam of the jaundice tester is natural light, the spectroscope divides the output light beam into a first incident light and a second incident light; the first optical filter enables light of a blue light wave band in the first incident light to pass through and blocks light outside the blue light wave band, and the second optical filter enables light of a green light wave band in the second incident light to pass through and blocks light outside the green light wave band; the first photoelectric conversion unit converts first incident light passing through the first optical filter into a first electrical signal, and the second photoelectric conversion unit converts second incident light passing through the second optical filter into a second electrical signal.
Optionally, the beam processing module includes a beam splitter, a first optical filter, a second optical filter, a first photoelectric conversion unit, and a second photoelectric conversion unit; the light beam processing module obtains a first incident light and a second incident light based on an output light beam of the jaundice tester, converts the first incident light into a first electric signal, and converts the second incident light into a second electric signal, and comprises: when the output light beam of the jaundice tester comprises blue light and green light, the spectroscope reflects the blue light to obtain the first incident light, transmits the green light to obtain the second incident light, and the blue light and the green light are output by the jaundice tester in a time-sharing way; the first optical filter enables light of a blue light wave band in the first incident light to pass through and blocks light outside the blue light wave band, and the second optical filter enables light of a green light wave band in the second incident light to pass through and blocks light outside the green light wave band; the first photoelectric conversion unit converts first incident light passing through the first optical filter into a first electrical signal, and the second photoelectric conversion unit converts second incident light passing through the second optical filter into a second electrical signal.
Optionally, the light beam processing module further includes a first attenuation sheet and a second attenuation sheet, where the first attenuation sheet is located between the beam splitter and the first photoelectric conversion unit, and the second attenuation sheet is located between the beam splitter and the second photoelectric conversion unit; the method further comprises the steps of: the first attenuation sheet adjusts the light intensity of the first incident light, and the second attenuation sheet adjusts the light intensity of the second incident light.
Optionally, the first electrical signal and the second electrical signal are analog signals, and the electrical signal processing module includes a first analog-to-digital converter, a second analog-to-digital converter, and a processing unit; the electrical signal processing module determines the light intensity of the first reflected light and the light intensity of the second reflected light based on a preset bilirubin concentration value, the first electrical signal, and the second electrical signal, comprising: the first analog-to-digital converter converts the first electrical signal into a first digital signal, and the second analog-to-digital converter converts the second electrical signal into a second digital signal; the processing unit obtains preset output light intensity of blue light and preset output light intensity of green light of the jaundice tester, and determines light intensity of the first reflected light and light intensity of the second reflected light based on the first digital signal, the second digital signal, the preset output light intensity of the blue light, the preset output light intensity of the green light and the preset bilirubin concentration value.
Optionally, the electric signal processing module further includes a first filter and a second filter, an output end of the first filter is connected with an input end of the first analog-to-digital converter, and an output end of the second filter is connected with an input end of the second analog-to-digital converter; the method further comprises the steps of: the first filter filters noise signals in the first electrical signal, and the second filter filters noise signals in the second electrical signal.
Optionally, the electric signal processing module further includes a first operational amplifier and a second operational amplifier, wherein an output end of the first operational amplifier is connected with an input end of the first filter, and an output end of the second operational amplifier is connected with an input end of the second filter; the method further comprises the steps of: the first operational amplifier amplifies the first electrical signal and the second operational amplifier amplifies the second electrical signal.
Optionally, the light emitting module includes a first driving unit, a second driving unit, a first light emitting unit, and a second light emitting unit; the light emitting module outputs a reflected light beam to the jaundice tester based on the light intensity of the first reflected light and the light intensity of the second reflected light, including: the first driving unit drives the first light emitting unit to output first reflected light based on the light intensity of the first reflected light, wherein the first reflected light is blue light; the second driving unit drives the second light emitting unit to output the second reflected light based on the light intensity of the second reflected light, wherein the second reflected light is green light.
Optionally, the light emitting module further comprises a beam combiner; the method further comprises the steps of: when the output light beam of the jaundice tester is natural light, the beam combiner combines the first reflected light beam and the second reflected light beam into a reflected light beam, and outputs the reflected light beam to the jaundice tester.
Optionally, the light emitting module further comprises a beam combiner, and the method further comprises: when the light beam output by the jaundice tester comprises blue light and green light, the beam combiner transmits the first reflected light and the second reflected light to the jaundice tester respectively.
A third aspect of the embodiments of the present application provides a computer readable storage medium storing a computer program which, when executed by the jaundice tester calibration apparatus, implements the steps of the method as described above.
Compared with the prior art, the embodiment of the application has the beneficial effects that:
in the jaundice tester calibration device provided by the embodiment of the application, the light beam processing module can obtain two paths of incident light based on the output light beam of the jaundice tester, and convert the two paths of incident light into electric signals. The electric signal processing module can determine the light intensity of two paths of reflected light based on the preset bilirubin concentration value and the electric signal obtained by converting the two paths of incident light, and then the control light emitting module outputs a simulated reflected light beam to the jaundice tester based on the light intensity of the two paths of reflected light, so that the jaundice tester can measure a bilirubin concentration value based on the simulated reflected light beam, and further the bilirubin concentration value is compared with the preset bilirubin concentration value to calibrate. Therefore, the calibration device provided by the embodiment of the application does not need to use a standard color card, can be suitable for jaundice testers produced by different manufacturers, and is more convenient and wider in applicability.
Drawings
Fig. 1 is a schematic structural diagram of a calibration device for a jaundice tester according to an embodiment of the present application;
fig. 2 is a schematic structural diagram of a beam processing module in a calibration device of a jaundice tester according to an embodiment of the present application;
fig. 3 is a schematic structural diagram of a beam processing module in another calibration device for a jaundice tester according to an embodiment of the present application;
fig. 4 is a schematic structural diagram of an electrical signal processing module in a calibration device of a jaundice tester according to an embodiment of the present application;
fig. 5 is a schematic structural diagram of an electrical signal processing module in another calibration device for a jaundice tester according to an embodiment of the present disclosure;
fig. 6 is a schematic structural diagram of a light emitting module in a calibration device of a jaundice tester according to an embodiment of the present application;
fig. 7 is a schematic structural diagram of a light emitting module in another calibration device for a jaundice tester according to an embodiment of the present disclosure;
fig. 8 is a flowchart of a method for calibrating a jaundice tester based on a jaundice tester calibration apparatus according to an embodiment of the present application.
Detailed Description
In order to make the technical problems, technical schemes and beneficial effects to be solved by the present application more clear, the present application is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the present application.
It should be noted that, in this application, the terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present application, the meaning of "a plurality" means two or more, and the meaning of "at least one" means one or more, unless specifically defined otherwise.
Next, an application scenario of the jaundice tester calibration device provided in the embodiments of the present application will be described.
Jaundice testers may also be referred to as percutaneous jaundice testers, for measuring bilirubin concentration values in the human body. Currently, there are two types of common jaundice testers, namely, a jaundice tester adopting a blue-green double-color light source, and a jaundice tester adopting a natural light source. When bilirubin concentration is measured by the jaundice tester, the probe of the jaundice tester is tightly attached to the skin of a human body. Then, for the jaundice tester adopting the blue-green dual-color light source, the blue light source and the green light source in the probe of the jaundice tester emit blue light and green light sequentially, and after the blue light and the green light pass through skin tissues of a human body, part of the blue light and the green light are absorbed, and the rest part of the blue light and the green light are reflected. Wherein, bilirubin in human body has a large absorbance of blue light, and hemoglobin absorbs blue light, and hemoglobin has substantially the same absorbance of blue light and green light. Based on the above, the probe of the jaundice tester can receive the blue light and the green light reflected by the skin tissue of the human body, and based on the light intensity of the reflected green light, the influence on the light intensity of the reflected blue light caused by the absorption of the blue light by the hemoglobin is removed, so that the bilirubin concentration value in the human body is calculated.
Unlike a jaundice tester using a blue-green light source, for a jaundice tester using a natural light source, the natural light source within the probe of the jaundice tester emits natural light. After natural light passes through skin tissue of human body, the blue light component and the green light component in the natural light can be absorbed and reflected as well, so that the probe of the jaundice tester can receive the reflected light, and based on the principle, the bilirubin concentration value in the human body can be calculated by the light intensity of the blue light component and the green light component in the reflected light.
The jaundice tester calibrating device that this application embodiment provided can be used for calibrating above-mentioned two kinds of jaundice testers to improve the measurement accuracy of jaundice tester.
Next, description will be given of a jaundice tester calibration device provided in an embodiment of the present application.
Fig. 1 is a schematic structural diagram of a calibration device 01 for a jaundice tester according to an embodiment of the present application. As shown in fig. 1, the jaundice tester calibration apparatus 01 includes a light beam processing module 10, an electrical signal processing module 11, and a light emitting module 12. The light beam processing module 10 is configured to obtain a first incident light and a second incident light based on an output light beam of the jaundice tester, and convert the first incident light into a first electrical signal and the second incident light into a second electrical signal; the electric signal processing module 11 is used for determining the light intensity of the first reflected light and the light intensity of the second reflected light based on a preset bilirubin concentration value, the first electric signal and the second electric signal; the light emitting module 12 is configured to output a reflected light beam to the jaundice tester based on the light intensity of the first reflected light and the light intensity of the second reflected light, so that the jaundice tester is calibrated based on the reflected light beam.
In the embodiment of the present application, the input end of the beam processing module 10 is aligned with the light source of the jaundice tester, or the input end of the beam processing module 10 is closely attached to the light source of the jaundice tester. Thus, when calibration is started, the jaundice tester to be calibrated is started, and the light source of the jaundice tester emits a light beam towards the input end of the light beam processing module 10. The beam processing module 10 receives an output beam of the jaundice tester, obtains a first incident light and a second incident light based on the output beam of the jaundice tester, and then converts the first incident light into a first electrical signal and converts the second incident light into a second electrical signal.
As illustrated in fig. 2, the beam processing module 10 may include a beam splitter 101, a first filter 102, a second filter 103, a first photoelectric conversion unit 104, and a second photoelectric conversion unit 105.
The beam splitter 101 faces the outgoing direction of the output beam of the jaundice tester, the first optical filter 102 is located on the reflection light path of the beam splitter 101, and the second optical filter 103 is located on the transmission light path of the beam splitter 101. The first photoelectric conversion unit 104 may be located in the exit direction of the first optical filter 102, and the second photoelectric conversion unit 105 may be located in the exit direction of the second optical filter 103.
In a first possible case, when the output beam of the jaundice tester is natural light, the beam splitter 101 is configured to split the output beam into a first incident light and a second incident light; the first optical filter 102 is used for passing light in a blue light band in the first incident light, blocking light outside the blue light band, and the second optical filter 103 is used for passing light in a green light band in the second incident light, blocking light outside the green light band; the first photoelectric conversion unit 104 is configured to convert first incident light passing through a first filter into a first electrical signal, and the second photoelectric conversion unit 105 is configured to convert second incident light passing through a second filter into a second electrical signal.
It should be noted that, when the jaundice tester adopts a natural light source, the output beam of the jaundice tester is a natural light beam, that is, a white light beam containing light components of different wavebands. In this case, after the output light beam is incident on the beam splitter 101, a part of the output light beam is reflected by the beam splitter 101 and reaches the first filter 102, where the part of the output light beam is the first incident light; another part of the output light beam passes through the beam splitter 101 and then reaches the second filter 103, and the part of the output light beam is the second incident light.
The beam splitter 101 may be a polarizing beam splitter prism, in which case the first incident light is S polarized light, and the second incident light is P polarized light. Of course, the beam splitter 101 may be another beam splitter that is independent of the polarization direction and is used to split one beam into two beams, which is not limited in the embodiment of the present application.
Since the first incident light and the second incident light both include light with different wavelengths, it is known based on the working principle of the jaundice tester described above that the jaundice tester mainly calculates bilirubin concentration values based on the light intensities of blue light and green light reflected after passing through human skin tissue. Based on this, in order to simulate blue light and green light reflected by human skin tissue later, in the embodiment of the present application, a first filter and a second filter may be further provided in the beam processing module 10. When the first incident light enters the first filter 102, the first filter 102 may pass light of a blue light band of the first incident light and block light of a wavelength band other than the blue light band, so as to filter light of a wavelength band other than the blue light of the first incident light. Similarly, when the second incident light enters the second filter 103, the second filter 103 may pass light of a green light band of the second incident light and block light of a band other than the green light, so as to filter out light of the second incident light of a band other than the green light.
The first filter 102 and the second filter 103 may be narrowband filters. In addition, the wavelength range of the blue light band through which the first filter 102 can pass may be 430nm to 480nm, and the wavelength range of the green light band through which the second filter can pass may be 520nm to 560nm. Of course, the wavelength range of the blue light band that the first filter 102 can pass may be appropriately adjusted with respect to the 460nm as the center wavelength, and the wavelength range of the green light band that the second filter 103 can pass may be appropriately adjusted with respect to the 550nm as the center wavelength, which is not limited in this embodiment.
Since the first photoelectric conversion unit 104 is located in the emission direction of the first filter 102, the second photoelectric conversion unit 105 is located in the emission direction of the second filter 103. Accordingly, the first incident light passing through the first filter 102 will be incident to the first photoelectric conversion unit 104, and the first photoelectric conversion unit 104 can convert the first incident light into a first electrical signal. Similarly, the second incident light passing through the second filter is incident on the second photoelectric conversion unit 105, and the second photoelectric conversion unit 105 can convert the second incident light into a second electric signal.
Wherein the first photoelectric conversion unit 104 and the second photoelectric conversion unit 105 are each a device for converting an optical signal into an electrical signal. The first photoelectric conversion unit 104 and the second photoelectric conversion unit 105 may be photodetectors, for example, photomultiplier tubes, but may be other types of photodetectors. In addition, the converted first electrical signal and second electrical signal may be analog signals.
In a second possible case, when the output beam of the jaundice tester includes blue light and green light, the beam splitter 101 is configured to reflect the blue light to obtain a first incident light, and transmit the green light to obtain a second incident light, where the blue light and the green light are output by the jaundice tester in a time-sharing manner.
It should be noted that, when the jaundice tester adopts the blue-green dual-color light source, the output light beam of the jaundice tester includes blue light and green light, and the blue light and the green light are alternately emitted in a time-sharing manner. For example, the jaundice tester may control the blue light source to continuously output blue light, and then control the green light source to continuously output green light, and then control the blue light source to continuously output blue light, until the output times of the blue light source and the output times of the green light source reach preset times.
Based on this, when the jaundice tester outputs blue light, the blue light is incident to the spectroscope 101, the spectroscope 101 reflects the incident blue light to the first optical filter 102, and at this time, the blue light reflected to the first optical filter 102 is the first incident light. Since the first filter 102 may pass light of the blue wavelength band, the first incident light may be incident to the first photoelectric conversion unit 104 through the first filter 102, so that the first incident light is converted into a first electrical signal by the first photoelectric conversion unit 104.
When the jaundice tester outputs green light, the green light enters the beam splitter 101 and then passes through the beam splitter 101 to reach the second optical filter 103, and at this time, the green light transmitted from the beam splitter 101 is the second incident light. Since the second filter 103 may pass light of the green wavelength band, the second incident light may be incident to the second photoelectric conversion unit 105 through the second filter 103, so that the second incident light is converted into a second electrical signal by the second photoelectric conversion unit 105.
It should be noted that, the blue light output by the jaundice tester may also be mixed with light of other wavelength bands during the process of reaching the first optical filter 102, so when the first incident light passes through the first optical filter 102, the first optical filter 102 may filter out light of other wavelength bands except the blue light band mixed in the first incident light, and similarly, the second optical filter 103 may also filter out light of other wavelength bands except the green light band mixed in the second incident light. In this way, the influence of light components of other wavebands on the calibration process can be avoided.
Optionally, referring to fig. 3, the beam processing module 10 further includes a first attenuation sheet 106 and a second attenuation sheet 107, where the first attenuation sheet 106 is located between the beam splitter 101 and the first photoelectric conversion unit 104, and the second attenuation sheet 107 is located between the beam splitter 101 and the second photoelectric conversion unit 105; the first attenuation sheet 106 is used for adjusting the light intensity of the first incident light, and the second attenuation sheet 107 is used for adjusting the light intensity of the second incident light.
It should be noted that, the first photoelectric conversion unit 104 and the second photoelectric conversion unit 105 may have a maximum light intensity supported, and the light intensities of the first incident light and the second incident light output by the beam splitter 101 may exceed the maximum light intensity. Based on this, in order to avoid that the light intensities of the incident lights respectively incident on the two photoelectric conversion units exceed the maximum light intensities supported by them as much as possible, the light intensity of the first incident light may be reduced by the first attenuation sheet 106, and the light intensity of the second incident light may be reduced by the second attenuation sheet 107.
In one possible implementation, a first attenuation sheet 106 may be located between the beam splitter 101 and the first optical filter 102, and a second attenuation sheet 107 is located between the beam splitter 101 and the second optical filter 103. Thus, the first incident light reflected by the beam splitter 101 passes through the first attenuation sheet 106 to reduce the light intensity, and then passes through the first filter 102 to filter out light in other wavelength bands than the blue light band. Similarly, the second incident light transmitted from the beam splitter 101 passes through the second attenuation sheet 107 to reduce the light intensity, and then passes through the second filter 103 to filter out light in other wavelength bands than the green light wavelength band.
In another possible implementation, the first attenuation sheet 106 may be located between the first optical filter 102 and the first photoelectric conversion unit 104, and the second attenuation sheet 107 may be located between the second optical filter 103 and the second photoelectric conversion unit 105. In this case, the first incident light passing through the first filter 102 reduces the light intensity through the first attenuation sheet 106, and then is incident on the first photoelectric conversion unit 104; the second incident light passing through the second filter 103 reduces the light intensity through the second attenuation sheet 107, and then is incident on the second photoelectric conversion unit 105.
After the beam processing module 10 converts the first incident light and the second incident light into the first electric signal and the second electric signal, the first electric signal and the second electric signal may be input to the electric signal processing module 11, and the electric signal processing module 11 may determine the light intensities of the first reflected light and the second reflected light to be simulated based on the preset bilirubin concentration value, the first electric signal, and the second electric signal.
For example, referring to fig. 4, the electrical signal processing module 11 may include a first analog-to-digital converter 111, a second analog-to-digital converter 112, and a processing unit 113. Wherein the first analog-to-digital converter 111 is used for converting the first electrical signal into a first digital signal, and the second analog-to-digital converter 112 is used for converting the second electrical signal into a second digital signal; the processing unit 113 is configured to obtain a preset output light intensity of blue light and a preset output light intensity of green light of the jaundice tester, and determine a light intensity of the first reflected light and a light intensity of the second reflected light based on the first digital signal, the second digital signal, the preset output light intensity of blue light, the preset output light intensity of green light, and the preset bilirubin concentration value.
In the embodiment of the present application, the first electrical signal and the second electrical signal output by the beam processing module 10 may be analog signals, and the signal supported by the processing unit 113 is a digital signal. Based on this. In the embodiment of the present application, the first electrical signal output by the beam processing module 10 may be converted into a first digital signal by the first analog-to-digital converter 111, and the second electrical signal output by the beam processing module 10 may be converted into a second digital signal by the second analog-to-digital converter 112. Thereafter, the first analog-to-digital converter 111 and the second analog-to-digital converter 112 may each transmit the converted first digital signal and second digital signal to the processing unit 113.
The processing unit 113 calculates the first light intensity according to the first digital signal after receiving the first digital signal, and calculates the second light intensity according to the second digital signal after receiving the second digital signal. The first light intensity is a blue light intensity measured value obtained by the calibration device 01 based on the output light beam of the jaundice tester, and the second light intensity is a green light intensity measured value obtained by the calibration device 01 based on the output light beam of the jaundice tester.
In addition, the processing unit 113 may also obtain the preset output light intensity of the blue light and the preset output light intensity of the green light of the calibrated jaundice tester. If the preset output light intensities of the first light intensity and the blue light satisfy the first condition and the preset output light intensity of the second light intensity and the green light satisfies the second condition, the processing unit 113 may acquire a blue reference reflected light intensity and a green reference reflected light intensity corresponding to the preset bilirubin concentration value, and calculate the light intensity of the first reflected light and the light intensity of the second reflected light based on the preset output light intensity of the blue light, the preset output light intensity of the green light, the first light intensity, the second light intensity, the blue reference reflected light intensity, and the green reference reflected light intensity.
For example, the calibration device 01 for a jaundice tester provided in the embodiments of the present application may further include an input/output unit, through which the processing unit 113 may receive the preset output light intensity of the blue light and the preset output light intensity of the green light of the jaundice tester input by the manufacturer of the jaundice tester. Thereafter, the processing unit 113 may compare the preset output light intensity of the blue light with the first light intensity, and if the absolute value of the difference between the preset output light intensity of the blue light and the first light intensity is not greater than the first threshold value and the first light intensity is not greater than the preset output light intensity of the blue light, it is indicated that the measured value of the blue light intensity obtained by the processing unit 113 is not greatly different from the preset output light intensity of the blue light, and in this case, it may be determined that the first light intensity and the preset output light intensity of the blue light satisfy the first condition. Similarly, the processing unit 113 may compare the preset output light intensity of the green light with the second light intensity, and determine that the preset output light intensity of the green light and the second light intensity satisfy the second condition if the absolute value of the difference between the preset output light intensity of the green light and the second light intensity is not greater than the second threshold value and the second light intensity is not greater than the preset output light intensity of the green light. The first threshold value and the second threshold value may be equal or unequal.
Optionally, if the absolute value of the difference between the preset output light intensity of the blue light and the first light intensity is greater than the third threshold value or the first light intensity is greater than the preset output light intensity of the blue light, it is indicated that the first light intensity and the preset output light intensity of the blue light have a larger difference, and at this time, it may be determined that the preset output light intensity of the first light intensity and the preset output light intensity of the blue light do not satisfy the first condition. If the absolute value of the difference between the preset output light intensity of the green light and the preset output light intensity of the second light intensity is larger than the fourth threshold value or the second light intensity is larger than the preset output light intensity of the green light, the fact that the difference between the second light intensity and the preset output light intensity of the green light is larger is indicated, and at the moment, it can be determined that the preset output light intensity of the second light intensity and the preset output light intensity of the green light do not meet the second condition. Wherein the third threshold is not smaller than the first threshold, the fourth threshold is not smaller than the second threshold, and the third threshold and the fourth threshold may be equal or not equal.
After determining that the preset output light intensities of the first light intensity and the blue light satisfy the first condition and the preset output light intensities of the second light intensity and the green light satisfy the second condition, the processing unit 113 may receive the preset bilirubin concentration value and the blue light reference reflected light intensity and the green light reference reflected light intensity corresponding to the preset bilirubin concentration value through the input output unit. Then, calculating to obtain the estimated reflected light intensity of the blue light based on the ratio of the preset output light intensity of the blue light to the first light intensity and the blue light reference reflected light intensity corresponding to the preset bilirubin concentration value; and calculating the estimated reflected light intensity of the green light based on the ratio of the preset output light intensity of the green light to the second light intensity and the reference reflected light intensity of the green light corresponding to the preset bilirubin concentration value. And then, determining the light intensity of the first reflected light and the light intensity of the second reflected light based on the ratio of the blue light reference reflected light intensity to the green light reference reflected light intensity corresponding to the preset bilirubin concentration value and the predicted reflected light intensity of the blue light and the predicted reflected light intensity of the green light, wherein the ratio of the light intensity of the first reflected light to the light intensity of the second reflected light is equal to the ratio of the blue light reference reflected light intensity to the green light reference reflected light intensity.
For example, assuming that the preset output intensity of blue light is 1000, the preset output intensity of green light is 800, the first intensity is 950, the second intensity is 750, the preset bilirubin concentration value is 10mg/dL, the blue light reference reflected intensity corresponding to the preset bilirubin concentration value is 500, the green light reference reflected light intensity is 400, the processing unit 113 may determine that the estimated reflected light intensity of blue light=500/(1000/950) =475, green predicted reflected light intensity=400/750/375. And then taking the predicted reflected light intensity of the blue light as the light intensity of the first reflected light, and calculating the light intensity of the second reflected light according to the ratio of the reference reflected light intensity of the blue light to the reference reflected light intensity of the green light and the light intensity of the first reflected light, wherein the light intensity of the second reflected light is=475 (500/400) =380. Alternatively, the estimated reflected light intensity of the green light may be used as the light intensity of the second reflected light, and the light intensity of the first reflected light may be calculated according to the ratio of the reference reflected light intensity of the blue light to the reference reflected light intensity of the green light and the light intensity of the second reflected light, where the light intensity=500++400×375=468.75.
Optionally, if the preset output light intensities of the first light intensity and the blue light do not meet the first condition, and/or the preset output light intensities of the second light intensity and the green light do not meet the second condition, the processing unit 113 may output an alarm prompt through the input/output unit to prompt that the jaundice tester is failed or fails.
Optionally, in some possible cases, the jaundice tester calibration device 01 provided in the embodiments of the present application may further include a storage unit, where reference parameters of the jaundice tester manufactured by the different manufacturers may be stored in advance. The reference parameters comprise preset output light intensity of blue light, preset output light intensity of green light and a mapping relation between bilirubin concentration values and reference reflected light intensity of a jaundice tester manufactured by corresponding manufacturers, wherein the mapping relation comprises blue light reference reflected light intensity and green light reference reflected light intensity corresponding to different bilirubin concentration values. Based on this, the processing unit 113 may receive, through the input/output unit, identification information of a manufacturer of the jaundice tester to be calibrated, obtain, according to the identification information, a preset output light intensity of blue light and a preset output light intensity of green light of the jaundice tester manufactured by the manufacturer, and determine, through the method described above, whether the first light intensity and the preset output light intensity of blue light satisfy the first condition, and whether the second light intensity and the preset output light intensity of green light satisfy the second condition. If both the first condition and the second condition are satisfied, the processing unit 113 may receive a preset bilirubin concentration value through the input-output unit. And then, based on the identification information of the manufacturer of the jaundice tester, acquiring a mapping relation included by the reference parameters of the manufacturer, and acquiring blue light reference reflected light intensity and green light reference reflected light intensity corresponding to a preset bilirubin concentration value from the mapping relation. Thereafter, the processing unit 113 may calculate the light intensity of the first reflected light and the light intensity of the second reflected light with reference to the above-described method.
Optionally, referring to fig. 5, in the embodiment of the present application, the electrical signal processing module 11 may further include a first filter 114 and a second filter 115, where an output end of the first filter 114 is connected to an input end of the first analog-to-digital converter 111, and an output end of the second filter 115 is connected to an input end of the second analog-to-digital converter 112; the first filter 114 is used for filtering noise signals in the first electrical signal, and the second filter 115 is used for filtering noise signals in the second electrical signal.
It should be noted that, a noise signal may be mixed in the electrical signal obtained by the optical conversion unit, and the noise signal may affect the accuracy of the light intensity of the first reflected light and the light intensity of the second reflected light that are determined later. Based on this, in the embodiment of the present application, a first filter 114 may also be connected between the first photoelectric conversion unit 104 and the first analog-to-digital converter 111. In this way, the first photoelectric conversion unit 104 may output the first electric signal to the first filter 114 after converting the first incident light into the first electric signal. The first filter 114 may filter the first electrical signal to remove noise signals in the first electrical signal, and then the first filter 114 may output the filtered first electrical signal to the first analog-to-digital converter 111. Similarly, a second filter 115 may be further connected between the second photoelectric conversion unit 105 and the second analog-to-digital converter 112, so as to filter noise signals in the second electrical signal.
Optionally, referring to fig. 5, the electrical signal processing module 11 may further include a first operational amplifier 116 and a second operational amplifier 117, wherein an output end of the first operational amplifier 116 is connected to an input end of the first filter 114, and an output end of the second operational amplifier 117 is connected to an input end of the second filter 115; the first operational amplifier 116 is used to amplify the first electrical signal and the second operational amplifier 117 is used to amplify the second electrical signal.
It should be noted that, the power of the electrical signal converted by the photoelectric conversion unit may be relatively small, so that the difficulty in determining the light intensity of the reflected light by using the digital signal obtained by converting the electrical signal later will be relatively large. Based on this, in the embodiment of the present application, the first operational amplifier 116 may be further connected between the first photoelectric conversion unit 104 and the first filter 114, so that the first photoelectric conversion unit 104 may output the converted first electrical signal to the first operational amplifier 116, and the first operational amplifier 116 amplifies the first electrical signal by a preset multiple. The amplified first electrical signal is then output to the first filter 114. Since the first operational amplifier 116 amplifies the first electrical signal, the noise signal in the first electrical signal is also amplified, and filtering the amplified first electrical signal by the first filter 114 can better remove the noise signal in the first electrical signal. Similarly, a second operational amplifier 117 may be further connected between the second photoelectric conversion unit 105 and the second filter 115, and the second electrical signal may be amplified by a predetermined multiple by the second operational amplifier 117, and then filtered by the second filter 115.
After determining, by the electrical signal processing module 11, the light intensity of the first reflected light and the light intensity of the second reflected light corresponding to the preset bilirubin concentration value, the electrical signal processing module 11 may control the light emitting module 12 to output the reflected light beam to the jaundice tester based on the light intensity of the first reflected light and the light intensity of the second reflected light.
For example, referring to fig. 6, the light emitting module 12 may include a first driving unit 121, a second driving unit 122, a first light emitting unit 123, and a second light emitting unit 124; wherein the first driving unit 121 is configured to drive the first light emitting unit 123 to output the first reflected light based on the light intensity of the first reflected light; the second driving unit 122 is configured to drive the second light emitting unit 124 to output the second reflected light based on the light intensity of the second reflected light. The first reflected light is blue light, and the second reflected light is green light.
It should be noted that, the first driving unit 121 and the second driving unit 122 may be connected to the processing unit 113 in the electrical signal processing module 11. In this way, the processing unit 113 may transmit the light intensity of the first reflected light to the first driving unit 121 and transmit the light intensity of the second reflected light to the second driving unit 122 after determining the light intensity of the first reflected light and the light intensity of the second reflected light.
The first driving unit 121 may drive the first light emitting unit 123 to emit blue light of a corresponding light intensity after receiving the light intensity of the first reflected light. At this time, the blue light is the first reflected light simulated by the calibration device 01. Similarly, the second driving unit 122 may drive the second light emitting unit 124 to emit green light of a corresponding intensity after receiving the intensity of the second reflected light. At this time, the green light is the second reflected light simulated by the calibration device 01. The first light emitting unit may be a blue LED (light-emitting diode) lamp, and the second light emitting unit may be a green LED lamp.
If the output light beam of the aforementioned jaundice tester to be calibrated includes blue light and green light, that is, the jaundice tester adopts a blue-green bi-color light source, the first driving unit 121 and the second driving unit 122 may time-divisionally drive the corresponding light emitting units to output reflected light. If the output light beam of the jaundice tester to be calibrated is natural light, that is, the jaundice tester adopts a natural light source, the first driving unit 121 and the second driving unit 122 may simultaneously drive the corresponding light emitting units to output reflected light.
It should be noted that, in one possible implementation manner of this embodiment of the present application, the light emitting directions of the first light emitting unit 123 and the second light emitting unit 124 are both towards the probe of the jaundice tester, so that the first reflected light emitted by the first light emitting unit 123 and the second reflected light emitted by the second light emitting unit 124 may directly enter the probe of the jaundice tester, and the jaundice tester may determine the bilirubin concentration measurement value based on the received light intensity measurement value of the first reflected light and the light intensity measurement value of the second reflected light.
Optionally, in another possible implementation of the embodiments of the present application, referring to fig. 7, the light emitting module 12 may further include a combiner 125. In this case, when the output beam of the jaundice tester is natural light, the beam combiner 125 is configured to combine the first reflected light and the second reflected light into a reflected beam, and output the reflected beam to the jaundice tester. When the output beam of the jaundice measuring instrument includes blue light and green light, the beam combiner 125 is configured to transmit the first reflected light and the second reflected light to the jaundice measuring instrument, respectively.
Specifically, the beam combiner 125 may be located in the light emitting directions of the first and second light emitting units 123 and 124, and the light emitting direction of the beam combiner 125 is toward the probe of the jaundice tester.
If the output beam of the jaundice tester is natural light, that is, the jaundice tester adopts a natural light source, it can be known from the foregoing description that the first driving unit 121 and the second driving unit 122 will simultaneously drive the corresponding light emitting units to emit reflected light. Based on this, the first reflected light emitted from the first light emitting unit 123 and the second reflected light emitted from the second light emitting unit 124 may be incident together on the beam combiner 125, and the beam combiner 125 combines the incident first reflected light and second reflected light into a reflected light beam and outputs the reflected light beam to the probe of the jaundice tester. After receiving the reflected light beam, the jaundice tester can measure the intensity of blue light and the intensity of green light in the reflected light beam to determine bilirubin concentration measurements.
If the output beam of the jaundice tester includes blue light and green light, that is, the jaundice tester adopts a blue-green dual-color light source, it can be seen from the foregoing description that the first driving unit 121 and the second driving unit 122 will time-divisionally drive the corresponding light emitting units to emit reflected light. Based on this, when the first light emitting unit 123 emits light, the first reflected light emitted by the first light emitting unit 123 enters the probe of the jaundice tester after passing through the beam combiner 125. When the second light emitting unit 124 emits light, the second emitted light emitted by the second light emitting unit 124 is incident to the probe of the jaundice tester after passing through the beam combiner 125. At this time, the first reflected light and the second reflected light incident to the jaundice tester at different times are reflected light beams output to the jaundice tester by the calibration device 01. Accordingly, the jaundice meter may determine the bilirubin concentration measurement based on the received light intensity measurement of the first reflected light and the light intensity measurement of the second reflected light.
After determining the bilirubin concentration measurement, the jaundice tester may compare the bilirubin concentration measurement with the previously described preset bilirubin concentration value. If the bilirubin concentration measurement is equal to a preset bilirubin concentration value, it may be determined that the jaundice tester does not need to be calibrated. If the bilirubin concentration measurement is not equal to the preset bilirubin concentration value, the jaundice test meter may be calibrated based on a difference between the bilirubin concentration measurement and the preset bilirubin concentration value.
In the jaundice tester calibration device provided by the embodiment of the application, the light beam processing module can obtain two paths of incident light based on the output light beam of the jaundice tester, and convert the two paths of incident light into electric signals. The electric signal processing module can determine the light intensity of two paths of reflected light based on the preset bilirubin concentration value and the electric signal obtained by converting the two paths of incident light, and then the control light emitting module outputs a simulated reflected light beam to the jaundice tester based on the light intensity of the two paths of reflected light, so that the jaundice tester can measure a bilirubin concentration value based on the simulated reflected light beam, and further the bilirubin concentration value is compared with the preset bilirubin concentration value to calibrate. Therefore, the calibration device provided by the embodiment of the application does not need to use a standard color card, can be suitable for jaundice testers produced by different manufacturers, and is more convenient and wider in applicability.
Based on the device for calibrating the jaundice tester introduced in the above embodiment, the embodiment of the application also provides a method for calibrating the jaundice tester based on the device for calibrating. As shown in fig. 8, the method includes the steps of:
step 801: the light beam processing module obtains first incident light and second incident light based on an output light beam of the jaundice tester, converts the first incident light into a first electric signal, and converts the second incident light into a second electric signal.
Optionally, the beam processing module includes a beam splitter, a first optical filter, a second optical filter, a first photoelectric conversion unit, and a second photoelectric conversion unit; in this case, when the output light beam of the jaundice tester is natural light, the light beam processing module obtains the first incident light and the second incident light based on the output light beam of the jaundice tester, and converts the first incident light into the first electrical signal, and the implementation process of converting the second incident light into the second electrical signal includes: the spectroscope divides the output light beam into a first incident light and a second incident light; the first optical filter enables light of a blue light wave band in the first incident light to pass through and blocks light outside the blue light wave band, and the second optical filter enables light of a green light wave band in the second incident light to pass through and blocks light outside the green light wave band; the first photoelectric conversion unit converts the first incident light passing through the first optical filter into a first electrical signal, and the second photoelectric conversion unit converts the second incident light passing through the second optical filter into a second electrical signal.
Optionally, when the output light beam of the jaundice tester includes blue light and green light, the blue light and the green light are output in a time-sharing manner, and the light beam processing module obtains the first incident light and the second incident light based on the output light beam of the jaundice tester, and converts the first incident light into the first electrical signal, and the implementation process of converting the second incident light into the second electrical signal includes: the spectroscope reflects blue light to the first optical filter and transmits green light to the second optical filter, wherein the first incident light is reflected blue light, and the second incident light is transmitted green light; the first optical filter enables light of a blue light wave band in the first incident light to pass through and blocks light outside the blue light wave band, and the second optical filter enables light of a green light wave band in the second incident light to pass through and blocks light outside the green light wave band; the first photoelectric conversion unit converts the first incident light passing through the first optical filter into a first electrical signal, and the second photoelectric conversion unit converts the second incident light passing through the second optical filter into a second electrical signal.
Optionally, the beam processing module may further include a first attenuation sheet and a second attenuation sheet, where the first attenuation sheet is located between the beam splitter and the first photoelectric conversion unit, and the second attenuation sheet is located between the beam splitter and the second photoelectric conversion unit; in this case, the first attenuation sheet may adjust the light intensity of the first incident light, and the second attenuation sheet adjusts the light intensity of the second incident light.
Alternatively, the first attenuation sheet may adjust the light intensity of the first incident light passing through the first filter, and the second attenuation sheet may adjust the light intensity of the second incident light passing through the second filter. Alternatively, the first attenuation sheet may adjust the light intensity of the first incident light reflected by the beam splitter, and the second attenuation sheet may adjust the light intensity of the second incident light transmitted by the beam splitter.
Step 802: the electric signal processing module determines the light intensity of the first reflected light and the light intensity of the second reflected light based on a preset bilirubin concentration value, the first electric signal and the second electric signal.
Optionally, the first electrical signal and the second electrical signal are analog signals, and the electrical signal processing module includes a first analog-to-digital converter, a second analog-to-digital converter and a processing unit; on the basis, the implementation process of determining the light intensity of the first reflected light and the light intensity of the second reflected light by the electric signal processing module based on the preset bilirubin concentration value, the first electric signal and the second electric signal comprises the following steps: the first analog-to-digital converter converts the first electric signal into a first digital signal, and the second analog-to-digital converter converts the second electric signal into a second digital signal; the processing unit obtains preset output light intensity of blue light and preset output light intensity of green light of the jaundice tester, and determines light intensity of the first reflected light and light intensity of the second reflected light based on the first digital signal, the second digital signal, the preset output light intensity of the blue light, the preset output light intensity of the green light and the preset bilirubin concentration value.
Optionally, the electric signal processing module further comprises a first filter and a second filter, wherein the output end of the first filter is connected with the input end of the first analog-to-digital converter, and the output end of the second filter is connected with the input end of the second analog-to-digital converter; in this case, the first filter may also filter out noise signals in the first electrical signal before the first analog-to-digital converter converts the first electrical signal into the first digital signal, and the second filter may also filter out noise signals in the second electrical signal before the second analog-to-digital converter converts the second electrical signal into the second digital signal.
Optionally, the electrical signal processing module may further include a first operational amplifier and a second operational amplifier, an output end of the first operational amplifier is connected to an input end of the first filter, and an output end of the second operational amplifier is connected to an input end of the second filter; on the basis, the first operational amplifier can also amplify the first electrical signal after the first filter filters out the noise signal in the first electrical signal, and the second operational amplifier can also amplify the second electrical signal before the second filter filters out the noise signal in the second electrical signal.
Step 803: the light emitting module outputs a reflected light beam to the jaundice tester based on the light intensity of the first reflected light and the light intensity of the second reflected light, so that the jaundice tester is calibrated based on the reflected light beam.
Optionally, the light emitting module includes a first driving unit, a second driving unit, a first light emitting unit, and a second light emitting unit; on the basis, the implementation process of the light emitting module outputting the reflected light beam to the jaundice tester based on the light intensity of the first reflected light and the light intensity of the second reflected light can include: the first driving unit drives the first light emitting unit to output first reflected light based on the light intensity of the first reflected light, wherein the first reflected light is blue light; the second driving unit drives the second light emitting unit to output second reflected light, which is green light, based on the light intensity of the second reflected light.
Optionally, the light emitting module further comprises a beam combiner; on the basis, when the output light beam of the jaundice tester is natural light, the implementation process can further comprise: the beam combiner combines the first reflected light and the second reflected light into a reflected light beam and outputs the reflected light beam to the jaundice tester.
Optionally, when the light beam output by the jaundice tester includes blue light and green light, the implementation process may further include: the beam combiner transmits the first reflected light and the second reflected light to the jaundice tester respectively.
It should be noted that, the specific implementation manner of each step in the foregoing method embodiment may refer to the related description in the foregoing embodiment, and the technical effects achieved by each step are similar to or the same as those achieved by the corresponding technical means in the foregoing embodiment, which is not described herein in detail.
In the foregoing embodiments, the descriptions of the embodiments are emphasized, and in part, not described or illustrated in any particular embodiment, reference is made to the related descriptions of other embodiments.
Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as optical and electronic hardware, or combinations of optical, computer software, and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the solution. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.
Where embodiments of the present application are implemented in software, they may be implemented in whole or in part in the form of a computer program product. That is, the present application may implement all or part of the flow of the method of the above embodiment, or may be implemented by a computer program to instruct related hardware, where the computer program may be stored in a computer readable storage medium, and when the computer program is executed by a processor, the computer program may implement the steps of the method embodiments described above. Wherein the computer program comprises computer program code, which may be in the form of source code, object code, executable files or in some intermediate form, etc. The computer readable medium may include: any entity or device capable of carrying computer program code, a recording medium, a U disk, a removable hard disk, a magnetic disk, an optical disk, a computer Memory, a Read-Only Memory (ROM), a random access Memory (RAM, random Access Memory), an electrical carrier signal, a telecommunications signal, a software distribution medium, and so forth. It should be noted that the content of the computer readable medium can be appropriately increased or decreased according to the requirements of the jurisdiction's jurisdiction and the patent practice, for example, in some jurisdictions, the computer readable medium does not include electrical carrier signals and telecommunication signals according to the jurisdiction and the patent practice.
The above embodiments are only for illustrating the technical solution of the present application, and are not limiting thereof; although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present application, and are intended to be included in the scope of the present application.

Claims (9)

1. The jaundice tester calibration device is characterized by comprising a light beam processing module, an electric signal processing module and a light emitting module;
the light beam processing module is used for obtaining first incident light and second incident light based on an output light beam of the jaundice tester, converting the first incident light into a first electric signal and converting the second incident light into a second electric signal;
the electric signal processing module is used for determining the light intensity of the first reflected light and the light intensity of the second reflected light based on a preset bilirubin concentration value, the first electric signal and the second electric signal;
The light emitting module is used for outputting a reflected light beam to the jaundice tester based on the light intensity of the first reflected light and the light intensity of the second reflected light so as to calibrate the jaundice tester based on the reflected light beam;
the first electric signal and the second electric signal are analog signals, and the electric signal processing module comprises a first analog-to-digital converter, a second analog-to-digital converter and a processing unit;
the first analog-to-digital converter is used for converting the first electric signal into a first digital signal, and the second analog-to-digital converter is used for converting the second electric signal into a second digital signal;
the processing unit is used for acquiring preset output light intensity of blue light and preset output light intensity of green light of the jaundice tester, and determining the light intensity of the first reflected light and the light intensity of the second reflected light based on the first digital signal, the second digital signal, the preset output light intensity of the blue light, the preset output light intensity of the green light and the preset bilirubin concentration value.
2. The jaundice tester calibration apparatus of claim 1, wherein the beam processing module comprises a beam splitter, a first optical filter, a second optical filter, a first photoelectric conversion unit, and a second photoelectric conversion unit;
When the output light beam of the jaundice tester is natural light, the spectroscope is used for dividing the output light beam into a first incident light and a second incident light;
the first optical filter is used for enabling light of a blue light wave band in the first incident light to pass through and blocking light outside the blue light wave band, and the second optical filter is used for enabling light of a green light wave band in the second incident light to pass through and blocking light outside the green light wave band;
the first photoelectric conversion unit is configured to convert first incident light passing through the first optical filter into a first electrical signal, and the second photoelectric conversion unit is configured to convert second incident light passing through the second optical filter into a second electrical signal.
3. The jaundice testing device of claim 2, wherein when the output beam of the jaundice testing device comprises blue light and green light output in a time-sharing manner, the beam splitter is configured to reflect the blue light to obtain the first incident light, and transmit the green light to obtain the second incident light.
4. A jaundice tester calibration apparatus as claimed in claim 2 or claim 3, wherein the beam processing module further comprises a first attenuation sheet and a second attenuation sheet, the first attenuation sheet being located between the beam splitter and the first photoelectric conversion unit, the second attenuation sheet being located between the beam splitter and the second photoelectric conversion unit;
The first attenuation sheet is used for adjusting the light intensity of the first incident light, and the second attenuation sheet is used for adjusting the light intensity of the second incident light.
5. The jaundice tester calibration apparatus of claim 1, wherein the electrical signal processing module further comprises a first filter and a second filter, the output of the first filter being connected to the input of the first analog-to-digital converter, the output of the second filter being connected to the input of the second analog-to-digital converter;
the first filter is used for filtering noise signals in the first electric signal, and the second filter is used for filtering noise signals in the second electric signal.
6. The jaundice test meter calibration of claim 5, wherein the electrical signal processing module further comprises a first operational amplifier and a second operational amplifier, the output of the first operational amplifier being coupled to the input of the first filter, the output of the second operational amplifier being coupled to the input of the second filter;
the first operational amplifier is used for amplifying the first electric signal, and the second operational amplifier is used for amplifying the second electric signal.
7. The jaundice tester calibration apparatus of claim 1, wherein the light emitting module comprises a first drive unit, a second drive unit, a first light emitting unit, and a second light emitting unit;
the first driving unit is used for driving the first light emitting unit to output first reflected light based on the light intensity of the first reflected light, and the first reflected light is blue light;
the second driving unit is used for driving the second light emitting unit to output second reflected light based on the light intensity of the second reflected light, and the second reflected light is green light.
8. The jaundice tester calibration apparatus of claim 7, wherein the light module further comprises a combiner;
when the output light beam of the jaundice tester is natural light, the beam combiner is used for combining the first reflected light beam and the second reflected light beam into a reflected light beam, and outputting the reflected light beam to the jaundice tester.
9. The jaundice test meter calibration fixture of claim 8, wherein the combiner is configured to transmit the first reflected light and the second reflected light to the jaundice test meter, respectively, when the output light beam of the jaundice test meter comprises blue light and green light output in a time-sharing manner.
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