CN116635007A - 用环糊精预防胆固醇结晶栓塞的方法 - Google Patents

用环糊精预防胆固醇结晶栓塞的方法 Download PDF

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Publication number
CN116635007A
CN116635007A CN202180066571.3A CN202180066571A CN116635007A CN 116635007 A CN116635007 A CN 116635007A CN 202180066571 A CN202180066571 A CN 202180066571A CN 116635007 A CN116635007 A CN 116635007A
Authority
CN
China
Prior art keywords
cyclodextrin
hydroxypropyl
individual
amount
cholesterol crystals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180066571.3A
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English (en)
Chinese (zh)
Inventor
D·克尔温
J·卡姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beren Treatment Public Welfare Co
Original Assignee
Beren Treatment Public Welfare Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beren Treatment Public Welfare Co filed Critical Beren Treatment Public Welfare Co
Publication of CN116635007A publication Critical patent/CN116635007A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
CN202180066571.3A 2020-08-27 2021-08-27 用环糊精预防胆固醇结晶栓塞的方法 Pending CN116635007A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063071243P 2020-08-27 2020-08-27
US63/071,243 2020-08-27
PCT/US2021/048075 WO2022047244A1 (en) 2020-08-27 2021-08-27 Methods for the prevention of cholesterol crystal embolization with cyclodextrins

Publications (1)

Publication Number Publication Date
CN116635007A true CN116635007A (zh) 2023-08-22

Family

ID=80352440

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180066571.3A Pending CN116635007A (zh) 2020-08-27 2021-08-27 用环糊精预防胆固醇结晶栓塞的方法

Country Status (11)

Country Link
US (1) US20230302042A1 (cg-RX-API-DMAC10.html)
EP (1) EP4203973A4 (cg-RX-API-DMAC10.html)
JP (1) JP7895334B2 (cg-RX-API-DMAC10.html)
KR (1) KR20230096976A (cg-RX-API-DMAC10.html)
CN (1) CN116635007A (cg-RX-API-DMAC10.html)
AU (1) AU2021331485A1 (cg-RX-API-DMAC10.html)
BR (1) BR112023003490A2 (cg-RX-API-DMAC10.html)
CA (1) CA3190764A1 (cg-RX-API-DMAC10.html)
IL (1) IL300881A (cg-RX-API-DMAC10.html)
MX (1) MX2023002420A (cg-RX-API-DMAC10.html)
WO (1) WO2022047244A1 (cg-RX-API-DMAC10.html)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877778A (en) * 1987-07-01 1989-10-31 The Children's Medical Center Corporation Method of enhancing lipophile transport using cyclodextrin derivatives
WO2013155485A2 (en) * 2012-04-13 2013-10-17 Alessia Fornoni Method of using cyclodextrin

Also Published As

Publication number Publication date
CA3190764A1 (en) 2022-03-03
WO2022047244A1 (en) 2022-03-03
MX2023002420A (es) 2023-07-11
JP2023543132A (ja) 2023-10-13
US20230302042A1 (en) 2023-09-28
EP4203973A4 (en) 2024-08-21
BR112023003490A2 (pt) 2023-05-09
JP7895334B2 (ja) 2026-07-27
AU2021331485A1 (en) 2023-03-23
EP4203973A1 (en) 2023-07-05
KR20230096976A (ko) 2023-06-30
IL300881A (en) 2023-04-01

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