CN116583192A - 用于调味的组合物和方法 - Google Patents
用于调味的组合物和方法 Download PDFInfo
- Publication number
- CN116583192A CN116583192A CN202180085140.1A CN202180085140A CN116583192A CN 116583192 A CN116583192 A CN 116583192A CN 202180085140 A CN202180085140 A CN 202180085140A CN 116583192 A CN116583192 A CN 116583192A
- Authority
- CN
- China
- Prior art keywords
- rebaudioside
- mogroside
- acid
- caffeoylquinic acid
- glucopyranosyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims description 51
- 238000000034 method Methods 0.000 title claims description 20
- 239000003765 sweetening agent Substances 0.000 claims abstract description 52
- 235000003599 food sweetener Nutrition 0.000 claims abstract description 49
- CWVRJTMFETXNAD-NXLLHMKUSA-N trans-5-O-caffeoyl-D-quinic acid Chemical compound O[C@H]1[C@H](O)C[C@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-NXLLHMKUSA-N 0.000 claims abstract description 40
- CWVRJTMFETXNAD-GMZLATJGSA-N 5-Caffeoyl quinic acid Natural products O[C@H]1C[C@](O)(C[C@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-GMZLATJGSA-N 0.000 claims abstract description 39
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 claims abstract description 35
- 239000000284 extract Substances 0.000 claims abstract description 33
- -1 tormentic acid compound Chemical class 0.000 claims abstract description 24
- OXVUXGFZHDKYLS-BLIWDXROSA-N Tormentic acid Natural products C1[C@@H](O)[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@](O)(C)[C@H]5C4=CC[C@@H]3[C@]21C OXVUXGFZHDKYLS-BLIWDXROSA-N 0.000 claims abstract description 23
- VULLSLYDWNGNKZ-UHFFFAOYSA-N 12319Tetrahydroxyurs-12-en-28-oic acid Natural products OC1C(O)C(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)C(O)(C)C5C4=CCC3C21C VULLSLYDWNGNKZ-UHFFFAOYSA-N 0.000 claims abstract description 12
- OXVUXGFZHDKYLS-UHFFFAOYSA-N Jacarandic acid Natural products C1C(O)C(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)C(O)(C)C5C4=CCC3C21C OXVUXGFZHDKYLS-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000003607 modifier Substances 0.000 claims abstract description 8
- 229930188195 rebaudioside Natural products 0.000 claims description 34
- 150000001875 compounds Chemical class 0.000 claims description 28
- 239000000796 flavoring agent Substances 0.000 claims description 19
- 235000019202 steviosides Nutrition 0.000 claims description 19
- 239000002253 acid Substances 0.000 claims description 15
- 239000004383 Steviol glycoside Substances 0.000 claims description 14
- 239000003205 fragrance Substances 0.000 claims description 14
- 235000019411 steviol glycoside Nutrition 0.000 claims description 14
- 229930182488 steviol glycoside Natural products 0.000 claims description 14
- UFCLZKMFXSILNL-RVXRWRFUSA-N 4,5-di-O-caffeoylquinic acid Chemical compound O([C@@H]1C[C@](O)(C[C@H]([C@@H]1OC(=O)\C=C\C=1C=C(O)C(O)=CC=1)O)C(O)=O)C(=O)\C=C\C1=CC=C(O)C(O)=C1 UFCLZKMFXSILNL-RVXRWRFUSA-N 0.000 claims description 13
- 235000019634 flavors Nutrition 0.000 claims description 13
- 239000002304 perfume Substances 0.000 claims description 13
- 150000007949 saponins Chemical class 0.000 claims description 13
- 150000008144 steviol glycosides Chemical class 0.000 claims description 13
- 240000000103 Potentilla erecta Species 0.000 claims description 12
- 235000016551 Potentilla erecta Nutrition 0.000 claims description 12
- 229930189775 mogroside Natural products 0.000 claims description 11
- 239000003814 drug Substances 0.000 claims description 10
- 229930006000 Sucrose Natural products 0.000 claims description 9
- 239000005720 sucrose Substances 0.000 claims description 9
- UFCLZKMFXSILNL-BBLPPJRLSA-N (-) 4,5-dicaffeoylquinic acid Natural products OC=1C=C(C=CC=1O)C=CC(=O)O[C@@H]1C[C@@](C[C@H]([C@H]1OC(C=CC1=CC(=C(C=C1)O)O)=O)O)(C(=O)O)O UFCLZKMFXSILNL-BBLPPJRLSA-N 0.000 claims description 8
- UFCLZKMFXSILNL-UHFFFAOYSA-N NSC 649410 Natural products C=1C=C(O)C(O)=CC=1C=CC(=O)OC1C(O)CC(O)(C(O)=O)CC1OC(=O)C=CC1=CC=C(O)C(O)=C1 UFCLZKMFXSILNL-UHFFFAOYSA-N 0.000 claims description 8
- 235000013361 beverage Nutrition 0.000 claims description 8
- 229930091371 Fructose Natural products 0.000 claims description 7
- 239000005715 Fructose Substances 0.000 claims description 7
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 7
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 7
- 239000000843 powder Substances 0.000 claims description 7
- GRWRKEKBKNZMOA-SJJZSDDKSA-N (2r,3r,4s,5s,6r)-2-[[(2r,3s,4s,5r,6r)-6-[[(3s,8s,9r,10r,11r,13r,14s,17r)-17-[(2r,5r)-5-[(2s,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[[(2s,3s,4r,5r,6s)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2 Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H](CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]6[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O6)O)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)C(C)(C)O)O[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O GRWRKEKBKNZMOA-SJJZSDDKSA-N 0.000 claims description 6
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 6
- VLVOZOYAJUACSG-UHFFFAOYSA-N Theogallin Natural products COc1cc(cc(OC)c1OC)C(=O)OC2CC(O)(CC(O)C2O)C(=O)O VLVOZOYAJUACSG-UHFFFAOYSA-N 0.000 claims description 6
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims description 6
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 6
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 6
- 239000008103 glucose Substances 0.000 claims description 6
- UFCLZKMFXSILNL-PSEXTPKNSA-N 3,4-di-O-Caffeoylquinic acid Natural products O([C@@H]1C[C@@](O)(C[C@H]([C@H]1OC(=O)\C=C\C=1C=C(O)C(O)=CC=1)O)C(O)=O)C(=O)\C=C\C1=CC=C(O)C(O)=C1 UFCLZKMFXSILNL-PSEXTPKNSA-N 0.000 claims description 5
- 230000002708 enhancing effect Effects 0.000 claims description 5
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 5
- 229940013618 stevioside Drugs 0.000 claims description 5
- 239000006188 syrup Substances 0.000 claims description 5
- 235000020357 syrup Nutrition 0.000 claims description 5
- WRPAFPPCKSYACJ-ZBYJYCAASA-N (2r,3r,4s,5s,6r)-2-[[(2r,3s,4s,5r,6r)-6-[[(3s,8r,9r,10s,11r,13r,14s,17r)-17-[(5r)-5-[(2s,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2r,3s,4r,5r,6s)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-hydroxy-6-methylheptan-2-yl]-11-hydrox Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H](CCC(C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]6[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O6)O)O5)O)CC4)(C)C)=CC[C@@H]3[C@]2(C)CC1)C)C(C)(C)O)[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O WRPAFPPCKSYACJ-ZBYJYCAASA-N 0.000 claims description 4
- UFCLZKMFXSILNL-GCBRTHAASA-N 102851-07-0 Natural products OC=1C=C(C=CC=1O)C=CC(=O)O[C@@H]1C[C@](C[C@H]([C@@H]1OC(C=CC1=CC(=C(C=C1)O)O)=O)O)(C(=O)O)O UFCLZKMFXSILNL-GCBRTHAASA-N 0.000 claims description 4
- YIEASZQRMGWKDX-UHFFFAOYSA-N 3,4-Di-O-caffeoylquinic acid Natural products OC1CC(O)(CC(OC(=O)C=Cc2ccc(O)c(O)c2)C1OC(=O)C=Cc3cccc(O)c3O)C(=O)O YIEASZQRMGWKDX-UHFFFAOYSA-N 0.000 claims description 4
- UFCLZKMFXSILNL-BKUKFAEQSA-N 3,4-di-O-caffeoylquinic acid Natural products O[C@H]1C[C@](O)(C[C@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1OC(=O)C=Cc3ccc(O)c(O)c3)C(=O)O UFCLZKMFXSILNL-BKUKFAEQSA-N 0.000 claims description 4
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 claims description 4
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 claims description 4
- WVXIMWMLKSCVTD-JLRHFDOOSA-N Mogroside II-E Chemical compound O([C@H](CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)C(C)(C)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O WVXIMWMLKSCVTD-JLRHFDOOSA-N 0.000 claims description 4
- 101000865553 Pentadiplandra brazzeana Defensin-like protein Proteins 0.000 claims description 4
- 235000019534 high fructose corn syrup Nutrition 0.000 claims description 4
- OKGRRPCHOJYNKX-UHFFFAOYSA-N mogroside IV A Natural products C1CC2(C)C3CC=C(C(C(OC4C(C(O)C(O)C(COC5C(C(O)C(O)C(CO)O5)O)O4)O)CC4)(C)C)C4C3(C)C(O)CC2(C)C1C(C)CCC(C(C)(C)O)OC(C(C(O)C1O)O)OC1COC1OC(CO)C(O)C(O)C1O OKGRRPCHOJYNKX-UHFFFAOYSA-N 0.000 claims description 4
- RPYRMTHVSUWHSV-CUZJHZIBSA-N rebaudioside D Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RPYRMTHVSUWHSV-CUZJHZIBSA-N 0.000 claims description 4
- QSRAJVGDWKFOGU-WBXIDTKBSA-N rebaudioside c Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]1(CC[C@H]2[C@@]3(C)[C@@H]([C@](CCC3)(C)C(=O)O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)CC3)C(=C)C[C@]23C1 QSRAJVGDWKFOGU-WBXIDTKBSA-N 0.000 claims description 4
- QSIDJGUAAUSPMG-CULFPKEHSA-N steviolmonoside Chemical compound O([C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O QSIDJGUAAUSPMG-CULFPKEHSA-N 0.000 claims description 4
- LDPLFHGGZNSKDS-FTBFGRRBSA-N theogallin Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)C1=CC(O)=C(O)C(O)=C1 LDPLFHGGZNSKDS-FTBFGRRBSA-N 0.000 claims description 4
- MBNNRMVOTYNNIX-HBEKLPNASA-N (3R,5R)-3,5-bis[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid Chemical compound C(\C=C\C1=CC(O)=C(O)C=C1)(=O)[C@]1(CC(C[C@](C1O)(O)C(\C=C\C1=CC(O)=C(O)C=C1)=O)(C(=O)O)O)O MBNNRMVOTYNNIX-HBEKLPNASA-N 0.000 claims description 3
- LDPLFHGGZNSKDS-CITXGKJTSA-N 5-O-galloylquinic acid Natural products O[C@H]1C[C@](O)(C[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H]1O)C(=O)O LDPLFHGGZNSKDS-CITXGKJTSA-N 0.000 claims description 3
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 claims description 3
- YWPVROCHNBYFTP-UHFFFAOYSA-N Rubusoside Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC1OC(CO)C(O)C(O)C1O YWPVROCHNBYFTP-UHFFFAOYSA-N 0.000 claims description 3
- 229920002472 Starch Polymers 0.000 claims description 3
- OMHUCGDTACNQEX-OSHKXICASA-N Steviolbioside Natural products O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O OMHUCGDTACNQEX-OSHKXICASA-N 0.000 claims description 3
- JLPRGBMUVNVSKP-AHUXISJXSA-M chembl2368336 Chemical compound [Na+].O([C@H]1[C@@H](O)[C@H](O)[C@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C([O-])=O)[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O JLPRGBMUVNVSKP-AHUXISJXSA-M 0.000 claims description 3
- YWPVROCHNBYFTP-OSHKXICASA-N rubusoside Chemical compound O([C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YWPVROCHNBYFTP-OSHKXICASA-N 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- LTDANPHZAHSOBN-IPIJHGFVSA-N (2R,3R,4S,5S,6R)-2-[[(2R,3S,4S,5R,6R)-6-[[(3S,8R,9R,10S,11R,13R,14S,17R)-17-[(2R,5R)-5-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-6-hydroxy-6-methylheptan-2-yl]-11-hydroxy-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-3,4-dihydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@H](CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]6[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O6)O)O5)O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)CC4)(C)C)=CC[C@@H]3[C@]2(C)CC1)C)C(C)(C)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O LTDANPHZAHSOBN-IPIJHGFVSA-N 0.000 claims description 2
- GHBNZZJYBXQAHG-KUVSNLSMSA-N (2r,3r,4s,5s,6r)-2-[[(2r,3s,4s,5r,6r)-6-[[(3s,8s,9r,10r,11r,13r,14s,17r)-17-[(2r,5r)-5-[(2s,3r,4s,5s,6r)-4,5-dihydroxy-3-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@H](CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]6[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O6)O)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)C(C)(C)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GHBNZZJYBXQAHG-KUVSNLSMSA-N 0.000 claims description 2
- XJIPREFALCDWRQ-UYQGGQRHSA-N (2r,3r,4s,5s,6r)-2-[[(2r,3s,4s,5r,6s)-3,4-dihydroxy-6-[(3r,6r)-2-hydroxy-6-[(3s,8s,9r,10r,11r,13r,14s,17r)-11-hydroxy-4,4,9,13,14-pentamethyl-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,7,8,10,11,12,15,16,17-decahydro-1h-cyclop Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@H](CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)C(C)(C)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O XJIPREFALCDWRQ-UYQGGQRHSA-N 0.000 claims description 2
- ACQZDPFYFKJNJQ-PCIVXFBTSA-N (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-[[(2r,3s,4s,5r,6s)-3,4,5-trihydroxy-6-[(3r,6r)-2-hydroxy-2-methyl-6-[(3s,8r,9r,10s,13r,14s,17r)-4,4,9,13,14-pentamethyl-3-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,7,8,10,11,12,15,16,17-deca Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)O[C@H](CC[C@@H](C)[C@@H]1[C@]2(CC[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)C(C)(C)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O ACQZDPFYFKJNJQ-PCIVXFBTSA-N 0.000 claims description 2
- KYVIPFHNYCKOMQ-YMRJDYICSA-N (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-[[(2r,3s,4s,5r,6s)-3,4,5-trihydroxy-6-[(3r,6r)-2-hydroxy-6-[(3s,8s,9r,10r,11r,13r,14s,17r)-11-hydroxy-4,4,9,13,14-pentamethyl-3-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,7,8,10,11,12,15,16,1 Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)O[C@H](CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)C(C)(C)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O KYVIPFHNYCKOMQ-YMRJDYICSA-N 0.000 claims description 2
- CGGWHBLPUUKEJC-HRTKKJOOSA-N (3S,8R,9R,10R,13R,14S,17R)-17-[(2R,5R)-5-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-6-hydroxy-6-methylheptan-2-yl]-4,4,9,13,14-pentamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one Chemical compound C[C@H](CC[C@@H](O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(C)(C)O)[C@H]1CC[C@@]2(C)[C@H]3CC=C4[C@@H](CC[C@H](O[C@@H]5O[C@H](CO[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@H]5O)C4(C)C)[C@]3(C)C(=O)C[C@]12C CGGWHBLPUUKEJC-HRTKKJOOSA-N 0.000 claims description 2
- ACQZDPFYFKJNJQ-UHFFFAOYSA-N 11-dehydroxymogroside III Natural products C1CC2(C)C3CC=C(C(C(OC4C(C(O)C(O)C(CO)O4)O)CC4)(C)C)C4C3(C)CCC2(C)C1C(C)CCC(C(C)(C)O)OC(C(C(O)C1O)O)OC1COC1OC(CO)C(O)C(O)C1O ACQZDPFYFKJNJQ-UHFFFAOYSA-N 0.000 claims description 2
- CGGWHBLPUUKEJC-UHFFFAOYSA-N 11-oxomogroside V Natural products C1CC2(C)C3CC=C(C(C(OC4C(C(O)C(O)C(COC5C(C(O)C(O)C(CO)O5)O)O4)O)CC4)(C)C)C4C3(C)C(=O)CC2(C)C1C(C)CCC(C(C)(C)O)OC(C(C(O)C1O)OC2C(C(O)C(O)C(CO)O2)O)OC1COC1OC(CO)C(O)C(O)C1O CGGWHBLPUUKEJC-UHFFFAOYSA-N 0.000 claims description 2
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 claims description 2
- 108010011485 Aspartame Proteins 0.000 claims description 2
- GUBGYTABKSRVRQ-CUHNMECISA-N D-Cellobiose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-CUHNMECISA-N 0.000 claims description 2
- 239000001512 FEMA 4601 Substances 0.000 claims description 2
- 239000001689 FEMA 4674 Substances 0.000 claims description 2
- 239000001776 FEMA 4720 Substances 0.000 claims description 2
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 claims description 2
- OMJOQOVMHUWPCF-VHLOEOCYSA-N Mogroside II B Chemical compound CC([C@H](O)CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)(C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O OMJOQOVMHUWPCF-VHLOEOCYSA-N 0.000 claims description 2
- KYVIPFHNYCKOMQ-UHFFFAOYSA-N Mogroside III Natural products C1CC2(C)C3CC=C(C(C(OC4C(C(O)C(O)C(CO)O4)O)CC4)(C)C)C4C3(C)C(O)CC2(C)C1C(C)CCC(C(C)(C)O)OC(C(C(O)C1O)O)OC1COC1OC(CO)C(O)C(O)C1O KYVIPFHNYCKOMQ-UHFFFAOYSA-N 0.000 claims description 2
- 239000004384 Neotame Substances 0.000 claims description 2
- HELXLJCILKEWJH-SEAGSNCFSA-N Rebaudioside A Natural products O=C(O[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)[C@@]1(C)[C@@H]2[C@](C)([C@H]3[C@@]4(CC(=C)[C@@](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@H](O)[C@@H](CO)O5)(C4)CC3)CC2)CCC1 HELXLJCILKEWJH-SEAGSNCFSA-N 0.000 claims description 2
- RLLCWNUIHGPAJY-RYBZXKSASA-N Rebaudioside E Natural products O=C(O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)[C@@H](O)[C@@H](O)[C@H](CO)O1)[C@]1(C)[C@@H]2[C@@](C)([C@@H]3[C@@]4(CC(=C)[C@@](O[C@@H]5[C@@H](O[C@@H]6[C@@H](O)[C@H](O)[C@@H](O)[C@H](CO)O6)[C@H](O)[C@@H](O)[C@H](CO)O5)(C4)CC3)CC2)CCC1 RLLCWNUIHGPAJY-RYBZXKSASA-N 0.000 claims description 2
- 239000004376 Sucralose Substances 0.000 claims description 2
- 229930182647 Trilobatin Natural products 0.000 claims description 2
- HINSNOJRHFIMKB-DJDMUFINSA-N [(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate Chemical compound [H][C@@]1(O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2OC(=O)[C@]2(C)CCC[C@@]3(C)[C@]4([H])CC[C@@]5(C[C@]4(CC5=C)CC[C@]23[H])O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O[C@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]2O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O HINSNOJRHFIMKB-DJDMUFINSA-N 0.000 claims description 2
- 235000010358 acesulfame potassium Nutrition 0.000 claims description 2
- 229960004998 acesulfame potassium Drugs 0.000 claims description 2
- 239000000619 acesulfame-K Substances 0.000 claims description 2
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims description 2
- 239000000605 aspartame Substances 0.000 claims description 2
- 235000010357 aspartame Nutrition 0.000 claims description 2
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 2
- 229960003438 aspartame Drugs 0.000 claims description 2
- CANAPGLEBDTCAF-UHFFFAOYSA-N dulcoside a Chemical compound OC1C(O)C(O)C(C)OC1OC1C(OC23C(CC4(C2)C(C2(C)C(C(CCC2)(C)C(=O)OC2C(C(O)C(O)C(CO)O2)O)CC4)CC3)=C)OC(CO)C(O)C1O CANAPGLEBDTCAF-UHFFFAOYSA-N 0.000 claims description 2
- HELXLJCILKEWJH-UHFFFAOYSA-N entered according to Sigma 01432 Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC(C1OC2C(C(O)C(O)C(CO)O2)O)OC(CO)C(O)C1OC1OC(CO)C(O)C(O)C1O HELXLJCILKEWJH-UHFFFAOYSA-N 0.000 claims description 2
- BJHIKXHVCXFQLS-PQLUHFTBSA-N keto-D-tagatose Chemical compound OC[C@@H](O)[C@H](O)[C@H](O)C(=O)CO BJHIKXHVCXFQLS-PQLUHFTBSA-N 0.000 claims description 2
- JLYBBRAAICDTIS-AYEHCKLZSA-N mogrol Chemical compound C([C@H]1[C@]2(C)CC[C@@H]([C@]2(C[C@@H](O)[C@]11C)C)[C@@H](CC[C@@H](O)C(C)(C)O)C)C=C2[C@H]1CC[C@H](O)C2(C)C JLYBBRAAICDTIS-AYEHCKLZSA-N 0.000 claims description 2
- JLYBBRAAICDTIS-UHFFFAOYSA-N mogrol Natural products CC12C(O)CC3(C)C(C(CCC(O)C(C)(C)O)C)CCC3(C)C1CC=C1C2CCC(O)C1(C)C JLYBBRAAICDTIS-UHFFFAOYSA-N 0.000 claims description 2
- LLZGAVAIPZROOJ-FDWAMWGASA-N mogroside IE Chemical compound C[C@H](CC[C@@H](O)C(C)(C)O)[C@H]1CC[C@@]2(C)[C@@H]3CC=C4[C@@H](CC[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C4(C)C)[C@]3(C)[C@H](O)C[C@]12C LLZGAVAIPZROOJ-FDWAMWGASA-N 0.000 claims description 2
- 229930191873 mogroside II Natural products 0.000 claims description 2
- WVXIMWMLKSCVTD-UHFFFAOYSA-N mogroside II E Natural products C1CC2(C)C3CC=C(C(C(OC4C(C(O)C(O)C(CO)O4)O)CC4)(C)C)C4C3(C)C(O)CC2(C)C1C(C)CCC(C(C)(C)O)OC1OC(CO)C(O)C(O)C1O WVXIMWMLKSCVTD-UHFFFAOYSA-N 0.000 claims description 2
- 229930191869 mogroside IV Natural products 0.000 claims description 2
- WRPAFPPCKSYACJ-UHFFFAOYSA-N mogroside IV E Natural products C1CC2(C)C3CC=C(C(C(OC4C(C(O)C(O)C(COC5C(C(O)C(O)C(CO)O5)O)O4)O)CC4)(C)C)C4C3(C)C(O)CC2(C)C1C(C)CCC(C(C)(C)O)OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(O)C1O WRPAFPPCKSYACJ-UHFFFAOYSA-N 0.000 claims description 2
- TVJXHJAWHUMLLG-UHFFFAOYSA-N mogroside V Natural products CC(CCC(OC1OC(COC2OC(CO)C(O)C(O)C2OC3OC(CO)C(O)C(O)C3O)C(O)C(O)C1O)C(C)(C)O)C4CCC5(C)C6CC=C7C(CCC(OC8OC(COC9OC(CO)C(O)C(O)C9O)C(O)C(O)C8O)C7(C)C)C6(C)C(O)CC45C TVJXHJAWHUMLLG-UHFFFAOYSA-N 0.000 claims description 2
- 235000019412 neotame Nutrition 0.000 claims description 2
- HLIAVLHNDJUHFG-HOTGVXAUSA-N neotame Chemical compound CC(C)(C)CCN[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 HLIAVLHNDJUHFG-HOTGVXAUSA-N 0.000 claims description 2
- 108010070257 neotame Proteins 0.000 claims description 2
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 claims description 2
- 235000019203 rebaudioside A Nutrition 0.000 claims description 2
- RLLCWNUIHGPAJY-SFUUMPFESA-N rebaudioside E Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RLLCWNUIHGPAJY-SFUUMPFESA-N 0.000 claims description 2
- QRGRAFPOLJOGRV-UHFFFAOYSA-N rebaudioside F Natural products CC12CCCC(C)(C1CCC34CC(=C)C(CCC23)(C4)OC5OC(CO)C(O)C(OC6OCC(O)C(O)C6O)C5OC7OC(CO)C(O)C(O)C7O)C(=O)OC8OC(CO)C(O)C(O)C8O QRGRAFPOLJOGRV-UHFFFAOYSA-N 0.000 claims description 2
- GSGVXNMGMKBGQU-PHESRWQRSA-N rebaudioside M Chemical compound C[C@@]12CCC[C@](C)([C@H]1CC[C@@]13CC(=C)[C@@](C1)(CC[C@@H]23)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GSGVXNMGMKBGQU-PHESRWQRSA-N 0.000 claims description 2
- HYLAUKAHEAUVFE-AVBZULRRSA-N rebaudioside f Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)CO1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HYLAUKAHEAUVFE-AVBZULRRSA-N 0.000 claims description 2
- XJIPREFALCDWRQ-UHFFFAOYSA-N siamenoside I Natural products C1CC2(C)C3CC=C(C(C(OC4C(C(O)C(O)C(CO)O4)O)CC4)(C)C)C4C3(C)C(O)CC2(C)C1C(C)CCC(C(C)(C)O)OC(C(C(O)C1O)OC2C(C(O)C(O)C(CO)O2)O)OC1COC1OC(CO)C(O)C(O)C1O XJIPREFALCDWRQ-UHFFFAOYSA-N 0.000 claims description 2
- 239000008107 starch Substances 0.000 claims description 2
- 235000019408 sucralose Nutrition 0.000 claims description 2
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims description 2
- 125000000185 sucrose group Chemical group 0.000 claims description 2
- 150000005846 sugar alcohols Chemical class 0.000 claims description 2
- GSTCPEBQYSOEHV-QNDFHXLGSA-N trilobatin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C=C1O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 GSTCPEBQYSOEHV-QNDFHXLGSA-N 0.000 claims description 2
- DRSKVOAJKLUMCL-MMUIXFKXSA-N u2n4xkx7hp Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O DRSKVOAJKLUMCL-MMUIXFKXSA-N 0.000 claims description 2
- LKDRXBCSQODPBY-JDJSBBGDSA-N D-allulose Chemical compound OCC1(O)OC[C@@H](O)[C@@H](O)[C@H]1O LKDRXBCSQODPBY-JDJSBBGDSA-N 0.000 claims 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims 1
- NUFKRGBSZPCGQB-FLBSXDLDSA-N (3s)-3-amino-4-oxo-4-[[(2r)-1-oxo-1-[(2,2,4,4-tetramethylthietan-3-yl)amino]propan-2-yl]amino]butanoic acid;pentahydrate Chemical compound O.O.O.O.O.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C NUFKRGBSZPCGQB-FLBSXDLDSA-N 0.000 claims 1
- PVXPPJIGRGXGCY-TZLCEDOOSA-N 6-O-alpha-D-glucopyranosyl-D-fructofuranose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)C(O)(CO)O1 PVXPPJIGRGXGCY-TZLCEDOOSA-N 0.000 claims 1
- 240000004246 Agave americana Species 0.000 claims 1
- 239000004377 Alitame Substances 0.000 claims 1
- 229930186291 Dulcoside Natural products 0.000 claims 1
- 239000001329 FEMA 3811 Substances 0.000 claims 1
- 239000001183 FEMA 4495 Substances 0.000 claims 1
- CWBZAESOUBENAP-QVNVHUMTSA-N Naringin dihydrochalcone Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](OC=2C=C(O)C(C(=O)CCC=3C=CC(O)=CC=3)=C(O)C=2)O[C@H](CO)[C@@H](O)[C@@H]1O CWBZAESOUBENAP-QVNVHUMTSA-N 0.000 claims 1
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 244000185386 Thladiantha grosvenorii Species 0.000 claims 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims 1
- 235000019409 alitame Nutrition 0.000 claims 1
- 108010009985 alitame Proteins 0.000 claims 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims 1
- 229940109275 cyclamate Drugs 0.000 claims 1
- HCAJEUSONLESMK-UHFFFAOYSA-N cyclohexylsulfamic acid Chemical compound OS(=O)(=O)NC1CCCCC1 HCAJEUSONLESMK-UHFFFAOYSA-N 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 235000013379 molasses Nutrition 0.000 claims 1
- ITVGXXMINPYUHD-CUVHLRMHSA-N neohesperidin dihydrochalcone Chemical compound C1=C(O)C(OC)=CC=C1CCC(=O)C(C(=C1)O)=C(O)C=C1O[C@H]1[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 ITVGXXMINPYUHD-CUVHLRMHSA-N 0.000 claims 1
- 229940089953 neohesperidin dihydrochalcone Drugs 0.000 claims 1
- 235000010434 neohesperidine DC Nutrition 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
- 235000019204 saccharin Nutrition 0.000 claims 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims 1
- 229940081974 saccharin Drugs 0.000 claims 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 claims 1
- 239000000047 product Substances 0.000 description 51
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 44
- 239000004615 ingredient Substances 0.000 description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 15
- 238000000605 extraction Methods 0.000 description 14
- 239000002904 solvent Substances 0.000 description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 235000019441 ethanol Nutrition 0.000 description 9
- 239000000463 material Substances 0.000 description 9
- 235000009508 confectionery Nutrition 0.000 description 8
- 235000000346 sugar Nutrition 0.000 description 8
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 7
- 235000014347 soups Nutrition 0.000 description 7
- 241000196324 Embryophyta Species 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 150000003839 salts Chemical class 0.000 description 6
- 235000002639 sodium chloride Nutrition 0.000 description 6
- 235000013305 food Nutrition 0.000 description 5
- 230000000873 masking effect Effects 0.000 description 5
- 235000013615 non-nutritive sweetener Nutrition 0.000 description 5
- 235000015067 sauces Nutrition 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 206010013911 Dysgeusia Diseases 0.000 description 4
- 150000007513 acids Chemical class 0.000 description 4
- 239000000654 additive Substances 0.000 description 4
- 239000011230 binding agent Substances 0.000 description 4
- 150000001720 carbohydrates Chemical class 0.000 description 4
- 235000014633 carbohydrates Nutrition 0.000 description 4
- 239000003085 diluting agent Substances 0.000 description 4
- 239000003995 emulsifying agent Substances 0.000 description 4
- 235000013355 food flavoring agent Nutrition 0.000 description 4
- 239000008123 high-intensity sweetener Substances 0.000 description 4
- 210000000214 mouth Anatomy 0.000 description 4
- 230000002123 temporal effect Effects 0.000 description 4
- 239000003643 water by type Substances 0.000 description 4
- RMLYXMMBIZLGAQ-UHFFFAOYSA-N (-)-monatin Natural products C1=CC=C2C(CC(O)(CC(N)C(O)=O)C(O)=O)=CNC2=C1 RMLYXMMBIZLGAQ-UHFFFAOYSA-N 0.000 description 3
- RMLYXMMBIZLGAQ-HZMBPMFUSA-N (2s,4s)-4-amino-2-hydroxy-2-(1h-indol-3-ylmethyl)pentanedioic acid Chemical compound C1=CC=C2C(C[C@](O)(C[C@H](N)C(O)=O)C(O)=O)=CNC2=C1 RMLYXMMBIZLGAQ-HZMBPMFUSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- WQZGKKKJIJFFOK-IVMDWMLBSA-N D-allopyranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@H](O)[C@@H]1O WQZGKKKJIJFFOK-IVMDWMLBSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000001476 alcoholic effect Effects 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 239000003963 antioxidant agent Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 description 3
- 239000000969 carrier Substances 0.000 description 3
- 235000013409 condiments Nutrition 0.000 description 3
- 239000000287 crude extract Substances 0.000 description 3
- 235000005911 diet Nutrition 0.000 description 3
- 230000000378 dietary effect Effects 0.000 description 3
- 239000008393 encapsulating agent Substances 0.000 description 3
- 238000005194 fractionation Methods 0.000 description 3
- 150000004676 glycans Chemical class 0.000 description 3
- 235000016709 nutrition Nutrition 0.000 description 3
- 235000019533 nutritive sweetener Nutrition 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 235000019198 oils Nutrition 0.000 description 3
- 239000000546 pharmaceutical excipient Substances 0.000 description 3
- 239000000419 plant extract Substances 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 239000005017 polysaccharide Substances 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 239000003381 stabilizer Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 235000021092 sugar substitutes Nutrition 0.000 description 3
- GYFFKZTYYAFCTR-JUHZACGLSA-N 4-O-trans-caffeoylquinic acid Chemical compound O[C@@H]1C[C@](O)(C(O)=O)C[C@@H](O)[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 GYFFKZTYYAFCTR-JUHZACGLSA-N 0.000 description 2
- QWIZNVHXZXRPDR-UHFFFAOYSA-N D-melezitose Natural products O1C(CO)C(O)C(O)C(O)C1OC1C(O)C(CO)OC1(CO)OC1OC(CO)C(O)C(O)C1O QWIZNVHXZXRPDR-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-SOOFDHNKSA-N D-ribopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@@H]1O SRBFZHDQGSBBOR-SOOFDHNKSA-N 0.000 description 2
- ZAQJHHRNXZUBTE-NQXXGFSBSA-N D-ribulose Chemical compound OC[C@@H](O)[C@@H](O)C(=O)CO ZAQJHHRNXZUBTE-NQXXGFSBSA-N 0.000 description 2
- ZAQJHHRNXZUBTE-UHFFFAOYSA-N D-threo-2-Pentulose Natural products OCC(O)C(O)C(=O)CO ZAQJHHRNXZUBTE-UHFFFAOYSA-N 0.000 description 2
- ZAQJHHRNXZUBTE-WUJLRWPWSA-N D-xylulose Chemical compound OC[C@@H](O)[C@H](O)C(=O)CO ZAQJHHRNXZUBTE-WUJLRWPWSA-N 0.000 description 2
- 239000001692 EU approved anti-caking agent Substances 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 2
- LKDRXBCSQODPBY-AMVSKUEXSA-N L-(-)-Sorbose Chemical compound OCC1(O)OC[C@H](O)[C@@H](O)[C@@H]1O LKDRXBCSQODPBY-AMVSKUEXSA-N 0.000 description 2
- SHZGCJCMOBCMKK-DHVFOXMCSA-N L-fucopyranose Chemical compound C[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@@H]1O SHZGCJCMOBCMKK-DHVFOXMCSA-N 0.000 description 2
- 240000008415 Lactuca sativa Species 0.000 description 2
- 229920002774 Maltodextrin Polymers 0.000 description 2
- 239000005913 Maltodextrin Substances 0.000 description 2
- 229920000881 Modified starch Polymers 0.000 description 2
- 108050004114 Monellin Proteins 0.000 description 2
- 241001092489 Potentilla Species 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-STGXQOJASA-N alpha-D-lyxopyranose Chemical compound O[C@@H]1CO[C@H](O)[C@@H](O)[C@H]1O SRBFZHDQGSBBOR-STGXQOJASA-N 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 238000012512 characterization method Methods 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 239000000306 component Substances 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 235000008504 concentrate Nutrition 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 239000008406 cosmetic ingredient Substances 0.000 description 2
- 235000013365 dairy product Nutrition 0.000 description 2
- 238000004807 desolvation Methods 0.000 description 2
- RXKJFZQQPQGTFL-UHFFFAOYSA-N dihydroxyacetone Chemical compound OCC(=O)CO RXKJFZQQPQGTFL-UHFFFAOYSA-N 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000000132 electrospray ionisation Methods 0.000 description 2
- 239000003925 fat Substances 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000005923 long-lasting effect Effects 0.000 description 2
- 229940035034 maltodextrin Drugs 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- QWIZNVHXZXRPDR-WSCXOGSTSA-N melezitose Chemical compound O([C@@]1(O[C@@H]([C@H]([C@@H]1O[C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O)CO)CO)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O QWIZNVHXZXRPDR-WSCXOGSTSA-N 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 235000019426 modified starch Nutrition 0.000 description 2
- 239000006072 paste Substances 0.000 description 2
- XNLFIERPGXTDDP-UHFFFAOYSA-N periandrin i Chemical compound C1CC(C2C(C3(CCC4(C)CCC(C)(C=C4C3CC2)C(O)=O)C)(C)CC2)(C=O)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O XNLFIERPGXTDDP-UHFFFAOYSA-N 0.000 description 2
- 239000003495 polar organic solvent Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 235000012045 salad Nutrition 0.000 description 2
- 235000014438 salad dressings Nutrition 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000001694 spray drying Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 239000000892 thaumatin Substances 0.000 description 2
- 235000010436 thaumatin Nutrition 0.000 description 2
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 description 2
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- YSCJAYPKBYRXEZ-HZPINHDXSA-N (2s,3s,4s,5r,6r)-6-[[(3s,4ar,6ar,6bs,8as,12as,14ar,14br)-4,4,6a,6b,11,11,14b-heptamethyl-8a-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3-hydroxy-4-[(2s,3r,4s, Chemical compound O([C@H]1[C@H](O)[C@H](O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@H]1CC[C@]2(C)[C@H]3CC=C4[C@@]([C@@]3(CC[C@H]2C1(C)C)C)(C)CC[C@]1(CCC(C[C@H]14)(C)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C(O)=O)[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O YSCJAYPKBYRXEZ-HZPINHDXSA-N 0.000 description 1
- AAWZDTNXLSGCEK-LNVDRNJUSA-N (3r,5r)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid Chemical compound O[C@@H]1CC(O)(C(O)=O)C[C@@H](O)C1O AAWZDTNXLSGCEK-LNVDRNJUSA-N 0.000 description 1
- QZOALWMSYRBZSA-PDSBIMDKSA-N (3r,5r,8r,9r,10r,13s,14r)-3-[(2r,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-10,13-dimethyl-17-[(1s)-1-[(2r,5s,6r)-5-methyl-6-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1C[C@H]2C(=O)C[C@@H]3[C@H]4CCC([C@]4(CC[C@H]3[C@@]2(C)CC1)C)[C@H](C)[C@@H]1O[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](C)CC1)[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O QZOALWMSYRBZSA-PDSBIMDKSA-N 0.000 description 1
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 description 1
- HNSDLXPSAYFUHK-UHFFFAOYSA-N 1,4-bis(2-ethylhexyl) sulfosuccinate Chemical compound CCCCC(CC)COC(=O)CC(S(O)(=O)=O)C(=O)OCC(CC)CCCC HNSDLXPSAYFUHK-UHFFFAOYSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- 238000001644 13C nuclear magnetic resonance spectroscopy Methods 0.000 description 1
- CZLVPINBLDRZCJ-UHFFFAOYSA-N 2,3,4,4,5,5,6,6-octachlorocyclohex-2-en-1-one Chemical compound ClC1=C(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C1=O CZLVPINBLDRZCJ-UHFFFAOYSA-N 0.000 description 1
- JUJWROOIHBZHMG-QYKNYGDISA-N 2-deuteriopyridine Chemical compound [2H]C1=CC=CC=N1 JUJWROOIHBZHMG-QYKNYGDISA-N 0.000 description 1
- NNXQSUSEFPRCRS-YCKMUKMSSA-N 3-[(3S,3aR,4R,5aR,6S,7S,9aR,9bR)-3-[(E,2S)-2,6-dihydroxy-6-methylhept-4-en-2-yl]-6,9a,9b-trimethyl-7-prop-1-en-2-yl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-1,2,3,3a,4,5,5a,7,8,9-decahydrocyclopenta[a]naphthalen-6-yl]propanoic acid Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1[C@@H]2[C@@H]([C@@](C)(O)C\C=C\C(C)(C)O)CC[C@@]2(C)[C@]2(C)CC[C@@H](C(C)=C)[C@](C)(CCC(O)=O)[C@H]2C1 NNXQSUSEFPRCRS-YCKMUKMSSA-N 0.000 description 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- DSHJQVWTBAAJDN-SMKXDYDZSA-N 4-caffeoylquinic acid Natural products CO[C@@]1(C[C@@H](O)[C@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@H](O)C1)C(=O)O DSHJQVWTBAAJDN-SMKXDYDZSA-N 0.000 description 1
- GYFFKZTYYAFCTR-UHFFFAOYSA-N 5-O-(6'-O-galloyl)-beta-D-glucopyranosylgentisic acid Natural products OC1CC(O)(C(O)=O)CC(O)C1OC(=O)C=CC1=CC=C(O)C(O)=C1 GYFFKZTYYAFCTR-UHFFFAOYSA-N 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 108010066676 Abrin Proteins 0.000 description 1
- CJHYXUPCGHKJOO-GUESNGNRSA-N Abrusoside A Natural products O=C(O)[C@]1(C)[C@@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)CC[C@@]23[C@H]1CC[C@H]1[C@@]4(C)[C@@](C)([C@H]([C@@H](C)[C@H]5OC(=O)C(C)=CC5)CC4)CC[C@@]21C3 CJHYXUPCGHKJOO-GUESNGNRSA-N 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- AAWZDTNXLSGCEK-UHFFFAOYSA-N Cordycepinsaeure Natural products OC1CC(O)(C(O)=O)CC(O)C1O AAWZDTNXLSGCEK-UHFFFAOYSA-N 0.000 description 1
- 241001137251 Corvidae Species 0.000 description 1
- GYFFKZTYYAFCTR-ZNEHSRBWSA-N Cryptochlorogensaeure Natural products O[C@@H]1C[C@@](O)(C[C@@H](O)[C@@H]1OC(=O)C=Cc2ccc(O)c(O)c2)C(=O)O GYFFKZTYYAFCTR-ZNEHSRBWSA-N 0.000 description 1
- YTBSYETUWUMLBZ-UHFFFAOYSA-N D-Erythrose Natural products OCC(O)C(O)C=O YTBSYETUWUMLBZ-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-CBPJZXOFSA-N D-Gulose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O WQZGKKKJIJFFOK-CBPJZXOFSA-N 0.000 description 1
- WQZGKKKJIJFFOK-WHZQZERISA-N D-aldose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-WHZQZERISA-N 0.000 description 1
- YTBSYETUWUMLBZ-IUYQGCFVSA-N D-erythrose Chemical compound OC[C@@H](O)[C@@H](O)C=O YTBSYETUWUMLBZ-IUYQGCFVSA-N 0.000 description 1
- MNQZXJOMYWMBOU-VKHMYHEASA-N D-glyceraldehyde Chemical compound OC[C@@H](O)C=O MNQZXJOMYWMBOU-VKHMYHEASA-N 0.000 description 1
- HSNZZMHEPUFJNZ-QMTIVRBISA-N D-keto-manno-heptulose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C(=O)CO HSNZZMHEPUFJNZ-QMTIVRBISA-N 0.000 description 1
- HAIWUXASLYEWLM-UHFFFAOYSA-N D-manno-Heptulose Natural products OCC1OC(O)(CO)C(O)C(O)C1O HAIWUXASLYEWLM-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
- LKDRXBCSQODPBY-OEXCPVAWSA-N D-tagatose Chemical compound OCC1(O)OC[C@@H](O)[C@H](O)[C@@H]1O LKDRXBCSQODPBY-OEXCPVAWSA-N 0.000 description 1
- YTBSYETUWUMLBZ-QWWZWVQMSA-N D-threose Chemical compound OC[C@@H](O)[C@H](O)C=O YTBSYETUWUMLBZ-QWWZWVQMSA-N 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 235000002722 Dioscorea batatas Nutrition 0.000 description 1
- 235000006536 Dioscorea esculenta Nutrition 0.000 description 1
- 240000001811 Dioscorea oppositifolia Species 0.000 description 1
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 description 1
- 239000004278 EU approved seasoning Substances 0.000 description 1
- 239000004386 Erythritol Substances 0.000 description 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 description 1
- 206010056474 Erythrosis Diseases 0.000 description 1
- PNNNRSAQSRJVSB-SLPGGIOYSA-N Fucose Natural products C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O PNNNRSAQSRJVSB-SLPGGIOYSA-N 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 241001506304 Kadsura japonica Species 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- SHZGCJCMOBCMKK-PQMKYFCFSA-N L-Fucose Natural products C[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O SHZGCJCMOBCMKK-PQMKYFCFSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VSOAQEOCSA-N L-altropyranose Chemical compound OC[C@@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-VSOAQEOCSA-N 0.000 description 1
- HSNZZMHEPUFJNZ-UHFFFAOYSA-N L-galacto-2-Heptulose Natural products OCC(O)C(O)C(O)C(O)C(=O)CO HSNZZMHEPUFJNZ-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-ZZWDRFIYSA-N L-glucose Chemical compound OC[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@H]1O WQZGKKKJIJFFOK-ZZWDRFIYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 108010022337 Leucine Enkephalin Proteins 0.000 description 1
- VTAJIXDZFCRWBR-UHFFFAOYSA-N Licoricesaponin B2 Natural products C1C(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2)C(O)=O)C)(C)CC2)(C)C2C(C)(C)CC1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O VTAJIXDZFCRWBR-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- QZOALWMSYRBZSA-UHFFFAOYSA-N Osladin Natural products C1CC(C)C(OC2C(C(O)C(O)C(C)O2)O)OC1C(C)C(C1(CCC2C3(C)CC4)C)CCC1C2CC(=O)C3CC4OC1OC(CO)C(O)C(O)C1OC1OC(C)C(O)C(O)C1O QZOALWMSYRBZSA-UHFFFAOYSA-N 0.000 description 1
- DLUTTXMPJCVUFR-HJCIYZGTSA-N Parillin Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O[C@H]1[C@@H]([C@H](O)[C@@H](O)[C@H](C)O1)O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@@H]1C[C@H]2CC[C@H]3[C@@H]4C[C@H]5[C@@H]([C@]4(CC[C@@H]3[C@@]2(C)CC1)C)[C@@H]([C@]1(OC[C@@H](C)CC1)O5)C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O DLUTTXMPJCVUFR-HJCIYZGTSA-N 0.000 description 1
- OFFJUHSISSNBNT-UHFFFAOYSA-N Polypodoside A Natural products C1CC(C)C(OC2C(C(O)C(O)C(C)O2)O)OC1C(C)C(C1(CCC2C3(C)CC4)C)CCC1C2=CC(=O)C3CC4OC1OC(CO)C(O)C(O)C1OC1OC(C)C(O)C(O)C1O OFFJUHSISSNBNT-UHFFFAOYSA-N 0.000 description 1
- AAWZDTNXLSGCEK-ZHQZDSKASA-N Quinic acid Natural products O[C@H]1CC(O)(C(O)=O)C[C@H](O)C1O AAWZDTNXLSGCEK-ZHQZDSKASA-N 0.000 description 1
- 244000081426 Ranunculus ficaria Species 0.000 description 1
- 235000002226 Ranunculus ficaria Nutrition 0.000 description 1
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 description 1
- CZMRCDWAGMRECN-UHFFFAOYSA-N Rohrzucker Natural products OCC1OC(CO)(OC2OC(CO)C(O)C(O)C2O)C(O)C1O CZMRCDWAGMRECN-UHFFFAOYSA-N 0.000 description 1
- 241000288961 Saguinus imperator Species 0.000 description 1
- HAIWUXASLYEWLM-AZEWMMITSA-N Sedoheptulose Natural products OC[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@](O)(CO)O1 HAIWUXASLYEWLM-AZEWMMITSA-N 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
- 244000020282 Solanum aculeatissimum Species 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 235000006468 Thea sinensis Nutrition 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- CJHYXUPCGHKJOO-AYOTXDKCSA-N abrusoside A Chemical compound O([C@H]1CC[C@@]23[C@H]([C@]1(C)C(O)=O)CC[C@H]1[C@]4(C)CC[C@@H]([C@]4(CC[C@]12C3)C)[C@H](C)[C@H]1OC(=O)C(C)=CC1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O CJHYXUPCGHKJOO-AYOTXDKCSA-N 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- YGCFIWIQZPHFLU-UHFFFAOYSA-N acesulfame Chemical compound CC1=CC(=O)NS(=O)(=O)O1 YGCFIWIQZPHFLU-UHFFFAOYSA-N 0.000 description 1
- 229960005164 acesulfame Drugs 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 235000013334 alcoholic beverage Nutrition 0.000 description 1
- PYMYPHUHKUWMLA-MROZADKFSA-N aldehydo-L-ribose Chemical compound OC[C@H](O)[C@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-MROZADKFSA-N 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000012223 aqueous fraction Substances 0.000 description 1
- 235000021168 barbecue Nutrition 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 235000020279 black tea Nutrition 0.000 description 1
- 235000012813 breadcrumbs Nutrition 0.000 description 1
- 235000021152 breakfast Nutrition 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229940074360 caffeic acid Drugs 0.000 description 1
- 235000004883 caffeic acid Nutrition 0.000 description 1
- 235000012970 cakes Nutrition 0.000 description 1
- 235000013574 canned fruits Nutrition 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 235000014171 carbonated beverage Nutrition 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 235000015218 chewing gum Nutrition 0.000 description 1
- 229940112822 chewing gum Drugs 0.000 description 1
- 229940104640 chinese yam extract Drugs 0.000 description 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 1
- 238000013375 chromatographic separation Methods 0.000 description 1
- 238000011210 chromatographic step Methods 0.000 description 1
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 description 1
- 230000009194 climbing Effects 0.000 description 1
- 235000014510 cooky Nutrition 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- GYFFKZTYYAFCTR-LMRQPLJMSA-N cryptochlorogenic acid Natural products O[C@H]1C[C@@](O)(C[C@H](O)[C@H]1OC(=O)C=Cc2ccc(O)c(O)c2)C(=O)O GYFFKZTYYAFCTR-LMRQPLJMSA-N 0.000 description 1
- 108010010165 curculin Proteins 0.000 description 1
- 229930193831 cyclocarioside Natural products 0.000 description 1
- 235000012869 dehydrated soup Nutrition 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 229940120503 dihydroxyacetone Drugs 0.000 description 1
- 235000021186 dishes Nutrition 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 235000021183 entrée Nutrition 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- YKLWRYOORWTCQQ-UHFFFAOYSA-N epiphyllanthine Natural products C1C23OC(=O)C=C2C=CC1N1CCC(OC)CC13 YKLWRYOORWTCQQ-UHFFFAOYSA-N 0.000 description 1
- 235000019414 erythritol Nutrition 0.000 description 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 1
- 229940009714 erythritol Drugs 0.000 description 1
- UQPHVQVXLPRNCX-UHFFFAOYSA-N erythrulose Chemical compound OCC(O)C(=O)CO UQPHVQVXLPRNCX-UHFFFAOYSA-N 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 235000019688 fish Nutrition 0.000 description 1
- 238000003818 flash chromatography Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 235000008378 frozen soup Nutrition 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 239000001087 glyceryl triacetate Substances 0.000 description 1
- 235000013773 glyceryl triacetate Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- LPLVUJXQOOQHMX-UHFFFAOYSA-N glycyrrhetinic acid glycoside Natural products C1CC(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2=O)C(O)=O)C)(C)CC2)(C)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O LPLVUJXQOOQHMX-UHFFFAOYSA-N 0.000 description 1
- 239000001685 glycyrrhizic acid Substances 0.000 description 1
- 229960004949 glycyrrhizic acid Drugs 0.000 description 1
- UYRUBYNTXSDKQT-UHFFFAOYSA-N glycyrrhizic acid Natural products CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(=O)O)OC6OC(C(O)C(O)C6OC7OC(O)C(O)C(O)C7C(=O)O)C(=O)O UYRUBYNTXSDKQT-UHFFFAOYSA-N 0.000 description 1
- 235000019410 glycyrrhizin Nutrition 0.000 description 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 235000009569 green tea Nutrition 0.000 description 1
- 230000007407 health benefit Effects 0.000 description 1
- 235000015243 ice cream Nutrition 0.000 description 1
- 125000002951 idosyl group Chemical class C1([C@@H](O)[C@H](O)[C@@H](O)[C@H](O1)CO)* 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- 235000014109 instant soup Nutrition 0.000 description 1
- RCRODHONKLSMIF-UHFFFAOYSA-N isosuberenol Natural products O1C(=O)C=CC2=C1C=C(OC)C(CC(O)C(C)=C)=C2 RCRODHONKLSMIF-UHFFFAOYSA-N 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- URLZCHNOLZSCCA-UHFFFAOYSA-N leu-enkephalin Chemical compound C=1C=C(O)C=CC=1CC(N)C(=O)NCC(=O)NCC(=O)NC(C(=O)NC(CC(C)C)C(O)=O)CC1=CC=CC=C1 URLZCHNOLZSCCA-UHFFFAOYSA-N 0.000 description 1
- 238000004895 liquid chromatography mass spectrometry Methods 0.000 description 1
- 239000012263 liquid product Substances 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 235000015090 marinades Nutrition 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 235000021180 meal component Nutrition 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000002032 methanolic fraction Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000000874 microwave-assisted extraction Methods 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 235000021096 natural sweeteners Nutrition 0.000 description 1
- 235000019520 non-alcoholic beverage Nutrition 0.000 description 1
- 239000002417 nutraceutical Substances 0.000 description 1
- 235000021436 nutraceutical agent Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000008601 oleoresin Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 235000015927 pasta Nutrition 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 150000007965 phenolic acids Chemical class 0.000 description 1
- FAASKPMBDMDYGK-UHFFFAOYSA-N phlomisoside I Natural products OC1C(O)C(O)C(C)OC1OC1C(O)C(O)C(CO)OC1OC1C(C)(C)C(CCC(C)=C2CCC3=COC=C3)C2(C)CC1 FAASKPMBDMDYGK-UHFFFAOYSA-N 0.000 description 1
- YKLWRYOORWTCQQ-HKUMRIAESA-N phyllanthine Chemical compound C1[C@@]23OC(=O)C=C2C=C[C@H]1N1CC[C@@H](OC)C[C@@H]13 YKLWRYOORWTCQQ-HKUMRIAESA-N 0.000 description 1
- 235000015108 pies Nutrition 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 150000003085 polypodoside A derivatives Polymers 0.000 description 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 description 1
- 235000012015 potatoes Nutrition 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 235000013594 poultry meat Nutrition 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- NNXQSUSEFPRCRS-UHFFFAOYSA-N pterocaryoside A Natural products OC1C(O)C(O)C(C)OC1OC1C2C(C(C)(O)CC=CC(C)(C)O)CCC2(C)C2(C)CCC(C(C)=C)C(C)(CCC(O)=O)C2C1 NNXQSUSEFPRCRS-UHFFFAOYSA-N 0.000 description 1
- 235000011962 puddings Nutrition 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 235000020095 red wine Nutrition 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 238000001223 reverse osmosis Methods 0.000 description 1
- 235000021462 rice dishes Nutrition 0.000 description 1
- HSNZZMHEPUFJNZ-SHUUEZRQSA-N sedoheptulose Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)CO HSNZZMHEPUFJNZ-SHUUEZRQSA-N 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 235000019613 sensory perceptions of taste Nutrition 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000000194 supercritical-fluid extraction Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 230000035923 taste sensation Effects 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 238000004704 ultra performance liquid chromatography Methods 0.000 description 1
- 238000002137 ultrasound extraction Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000015192 vegetable juice Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/84—Flavour masking or reducing agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/88—Taste or flavour enhancing agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/36—Terpene glycosides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/15—Flavour affecting agent
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/16—Taste affecting agent
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/21—Plant extracts
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Seasonings (AREA)
- General Preparation And Processing Of Foods (AREA)
- Dairy Products (AREA)
- Tea And Coffee (AREA)
- Non-Alcoholic Beverages (AREA)
- Medicinal Preparation (AREA)
Abstract
提供了消费品。所述消费品包括：(a)至少一种甜味剂，和(b)甜度改良剂，其包含来自须药藤的提取物或级分或至少一种咖啡酰奎尼酸或委陵菜酸化合物。所述至少一种甜味剂以增甜量存在。
Description
技术领域
本公开涉及组合物和方法，其在香料组合物和消费品中使用来自须药藤(Stelmatocrypton khasianum)的提取物或级分和一种或多种分离自须药藤的咖啡酰奎尼酸和/或委陵菜酸化合物，例如用于改善甜度，改善口感和掩蔽消费品的异常特征。
背景
广泛使用用于改良消费品(即口服用于摄取或吐出的产品，例如食品，饮料，糖食，口腔护理产品等)的味道的化合物。它们本身不向消费品添加风味，但它们提供期望的辅助益处，例如增强的口感和/或甜味或掩蔽其它成分的不期望的特征，例如被认为不吸引人的包含糖替代物的产品的独特味道和质地。
在糖替代物的情况下，与它们替代的糖相比，它们赋予的味道可以整体或部分地呈现不同的时间特征，香味特征或适应行为。例如，天然和合成的高甜度甜味剂(HIS)的甜味通常比由糖(甜味的，短链可溶性碳水化合物，包括葡萄糖，果糖，蔗糖，麦芽糖和乳糖)或称作糖替代物的高果糖玉米糖浆(HFCS)产生的甜味起效更慢且持续时间更长，并且这可能改变包含它们的可食用组合物的味道平衡。这可能产生不平衡的时间味觉特征。除了时间特征的差异之外，高强度甜味剂通常表现出比糖更低的最大响应；异味，包括苦味，金属味，清凉味，涩味，甘草样味道和/或甜味，其在反复品尝时减少。
然而，所有高强度甜味剂均具有异常特征形式的不期望的余味，例如甘草样余味和/或持久的甜味。在Reb A的特定情况下，这表现为不期望的持久的甜味和甘草样余味的组合的形式。这种余味降低了期望的糖样甜味，因此有效地掩蔽可食用组合物中的不期望的味道或异味是消费者接受许多可食用组合物的关键。
因此，仍然需要提供天然的和/或适合于严格素食者的味道改良成分，提取物或级分，即“更清洁的标签”，同时改善口感，掩蔽异常特征和/或改善消费品的甜度。
概述
在一个示例性实施方案中，消费品组合物包含：(a)至少一种甜味剂，和(b)甜度改良剂，其包含来自须药藤的提取物或级分或至少一种咖啡酰奎尼酸或委陵菜酸化合物。所述至少一种甜味剂以增甜量存在。
在另一个示例性实施方案中，香料组合物包含来自须药藤的提取物或级分或至少一种分离自须药藤的咖啡酰奎尼酸或委陵菜酸化合物。
在仍然另一个示例性实施方案中，增强包含甜味剂的消费品甜度或口感的方法包括以有效改良所述消费品的甜度或口感的量向所述消费品中添加来自须药藤的提取物或级分或至少一种咖啡酰奎尼酸或委陵菜酸化合物。
在仍然另一个示例性实施方案中，香料组合物包含选自下组的化合物：3-没食子酰基奎尼酸，5-O-没食子酰基奎尼酸，星型三萜苷(stelmatotriterpenoside)E，F和G，星型三萜苷I(3-O-β-D-吡喃葡萄糖基-28-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2α,3β-二羟基-乌苏-12-烯-28-酸)，星型三萜苷J(3-O-β-D-吡喃葡萄糖基-28-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2α,3β,19α-三羟基-乌苏-12-烯-28-酸)，星型三萜苷K(3-O-β-D-吡喃葡萄糖基-28-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2α,3β-二羟基-齐墩果-12-烯-28-酸)及其组合。
通过阅读本公开，具体实施方案的这些和其它特征，方面和优点对于本领域技术人员将变得显而易见。
详细描述
以下文本阐述了本公开的许多不同实施方案的广泛描述。该描述应被解释为仅是示例性的，并且不描述每个可能的实施方案，因为描述每个可能的实施方案即使不是不可能也是不切实际的。应当理解，本文所述的任何特性，特征，组分，组合物，成分，产品，步骤或方法可以全部或部分地删除，组合或替代任何其它特性，特征，组分，组合物，成分，产品，步骤或方法。可以使用当前技术或在本专利的申请日之后开发的技术来实施许多替代实施方案，这将仍然落入权利要求的范围内。本文引用的所有出版物和专利均通过引用并入本文。
本公开涉及以下令人惊讶的发现：来自须药藤(S.khasianum)的提取物或级分和一种或多种分离自所述须药藤提取物或级分的咖啡酰奎尼酸化合物表现出甜味改良效果以及口感改良和掩蔽特性。特别地，本公开涉及以下令人惊讶的发现：可以使用来自须药藤的提取物或级分和一种或多种分离自所述须药藤的咖啡酰奎尼酸和/或委陵菜酸化合物，例如，以改善低糖或无热量甜味剂的时间特征，使它们更接近全糖体验。
须药藤是一种木质攀缘藤本植物。它分布在中国的西南省份，即云南，贵州，广西和四川。须药藤的叶和茎在传统上用于治疗感冒，胃痛，气管炎和风湿性疼痛的中药中。
所有或部分须药藤植物可用于本方法。在一个实施方案中，在提取之前部分干燥须药藤植物材料。在另一个实施方案中，在提取之前完全干燥须药藤植物材料。在一些实施方案中，任选地在提取之前研磨该植物材料。
该植物材料可以通过任何合适的提取方法提取，例如连续或分批回流提取，超临界流体提取，酶辅助提取，微生物辅助提取，超声辅助提取，微波辅助提取等。这些方法可以以任意规模运用。
用于提取的溶剂可以是任何合适的溶剂，例如极性有机溶剂(脱气的，利用真空的，加压的或蒸馏的)，非极性有机溶剂，水(脱气的，利用真空的，加压的，去离子的，蒸馏的，碳处理的或反渗透)或其混合物。在一个具体实施方案中，所述溶剂包含水和一种或多种醇。在一个具体实施方案中，所述溶剂包含水和选自甲醇，乙醇，正丙醇，2-丙醇，1-丁醇，2-丁醇及其混合物的醇。
所述溶剂中醇的量可以在约10％至约100％之间变化，例如约20％，约30％，约40％，约50％，约60％，约70％，约80％，约90％或其间的任何范围。在一个具体实施方案中，醇占溶剂的80％至约100％，其余为水。
在一些实施方案中，提取过程在升高的温度下进行，例如约50℃至约100℃。在一个更具体的实施方案中，提取过程在约100℃的温度下进行。
本领域技术人员将理解，提取的持续时间将基于所使用的溶剂和植物材料的量而变化。在一些实施方案中，提取进行约10分钟至约24小时。可以从提取混合物中除去水和/或任何不溶性物质以提供“粗提取物”。
可以通过例如过滤将不溶性植物材料与提取的混合物分离。其它合适的分离方法包括但不限于重力过滤，板框压滤机，错流过滤器，筛网过滤器，Nutsche过滤器，带式过滤器，陶瓷过滤器，膜过滤器，微型过滤器，纳米过滤器，超滤器或离心。任选地，在该方法中可以使用各种助滤剂，例如硅藻土，膨润土，沸石等。
然后对粗提取物进行一次或多次色谱分离，以提供本文所述的至少一种咖啡酰奎尼酸或委陵菜酸化合物的溶液。使粗提取物通过一个或多个柱，例如填充有聚合吸附树脂的那些柱。用甲醇水溶液洗脱所述一个或多个柱提供了包含植物提取物级分的溶液。在一个实施方案中，首先使10％乙醇上柱并收集洗脱液。可以基于用于洗脱的％甲醇，例如0％甲醇，30％甲醇，50％甲醇，70％甲醇和100％甲醇收集级分。典型地，在多个级分中收集色谱步骤的产物，其然后可以使用任何合适的技术，例如薄层色谱法或质谱法分析。
根据本公开，须药藤的级分可以包括咖啡酰奎尼酸化合物。咖啡酰奎尼酸为酚酸以及多酚咖啡酸和奎尼酸的酯。在另一个实施方案中，须药藤的级分可以包括委陵菜酸化合物。委陵菜酸为三萜类化合物。
在一个实施方案中，本公开的咖啡酰奎尼酸和委陵菜酸化合物为甜度改良剂。如本文所用，术语“甜度改良剂”是指当化合物以处于或低于该化合物的甜味剂识别阈值的浓度(即在不存在一种或多种另外的甜味剂的情况下该化合物不贡献任何明显的甜味的浓度)存在于消费品中时，改良，增强，放大或加强所述消费品的甜度感知的化合物。
如本文所用，术语“甜度识别阈值浓度”是可被人类味觉感知为甜味的化合物的最低已知浓度。
在另一个实施方案中，本公开的咖啡酰奎尼酸和委陵菜酸化合物为调味剂，同时充当或不充当甜度改良剂。也就是说，在一些实施方案中，所述咖啡酰奎尼酸和委陵菜酸化合物改良甜度并调节甜味剂的一种或多种味道属性。在其它实施方案中，所述咖啡酰奎尼酸和委陵菜酸化合物改良甜味剂的甜度而不调节所述甜味剂的一种或多种味道属性。在仍然其它实施方案中，所述咖啡酰奎尼酸和委陵菜酸化合物调节甜味剂的一种或多种味道属性而不改良所述甜味剂的甜度。
在一个具体的实施方案中，下式(I至VI)的咖啡酰奎尼酸化合物用作甜度改良剂和/或味道改良剂：
5-O-咖啡酰奎尼酸(CAS编号906-33-2)
3-O-咖啡酰奎尼酸(CAS编号327-97-9)
4-O-咖啡酰奎尼酸(CAS编号905-99-7)
4,5-二-O-咖啡酰奎尼酸(CAS编号57378-72-0)
3,5-二-咖啡酰奎尼酸(CAS编号2450-53-5)
3,4-二-O-咖啡酰奎尼酸(CAS编号14534-61-3)
因此，根据一个实施方案，所述至少一种咖啡酰奎尼酸化合物可以选自5-O-咖啡酰奎尼酸，3-O-咖啡酰奎尼酸，4-O-c酸(4-O-c Aci)，4,5-二-O-咖啡酰奎尼酸，3,5-二-咖啡酰奎尼酸，3,4-二-O-咖啡酰奎尼酸及其组合。
在另一个具体的实施方案中，下式(VII)的委陵菜酸化合物用作甜度改良剂和/或味道改良剂：
委陵菜酸(CAS编号13850-16-3)
根据本公开，通过LC-MS和NMR光谱分析鉴定了来自须药藤提取物的级分的另外的已知和未知的化合物。那些化合物包括如下：3-没食子酰基奎尼酸(CAS编号17365-11-6)，5-O-没食子酰基奎尼酸(CAS编号53584-43-3)，星型三萜苷E，F和G(C48H80O20)和星型三萜苷I(3-O-β-D-吡喃葡萄糖基-28-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2α,3β-二羟基-乌苏-12-烯-28-酸，C48H80O19)，星型三萜苷J(3-O-β-D-吡喃葡萄糖基-28-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2α,3β,19α-三羟基-乌苏-12-烯-28-酸，C48H80O20)和星型三萜苷K(3-O-β-D-吡喃葡萄糖基-28-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2α,3β-二羟基-齐墩果-12-烯-28-酸，C48H80O19)。
可以以纯形式或作为混合物组成部分提供本文所述的咖啡酰奎尼酸和委陵菜酸化合物。所述混合物可以为由如本文所述的植物或植物部分制备的提取物或级分。
来自须药藤的提取物或级分和/或如本文所述的一种或多种咖啡酰奎尼酸和委陵菜化合物改良和/或调节至少一种甜味剂的味道。所述至少一种甜味剂可以为任何已知的甜味剂，例如天然甜味剂，天然高效甜味剂或合成甜味剂。
所述至少一种甜味剂以增甜量存在。如本文所用，“增甜量”是指当存在于消费品例如饮料中时提供可检测到的甜度所需的化合物的量。
如本文所用，短语“天然高效甜味剂”是指在自然界中天然发现的任何甜味剂，并且特征性地具有大于蔗糖，果糖或葡萄糖的甜度效力，但具有较低的卡路里。天然高效甜味剂可以作为纯化合物提供，或者作为提取物的一部分提供。如本文所用，短语“合成甜味剂”是指在自然界中不是天然存在的并且特征性地具有大于蔗糖，果糖或葡萄糖的甜度效力但具有较低卡路里的任何组合物。
在其它实施方案中，所述至少一种甜味剂是碳水化合物甜味剂。合适的碳水化合物甜味剂选自但不限于蔗糖，甘油醛，二羟基丙酮，赤藓糖，苏糖，赤藓酮糖，阿拉伯糖，来苏糖，核糖，木糖，核酮糖，木酮糖，阿洛糖，阿卓糖，半乳糖，葡萄糖，古洛糖，艾杜糖，甘露糖，塔罗糖，果糖，阿洛酮糖，山梨糖，塔格糖，甘露庚酮糖，景天庚酮糖，辛酮糖，岩藻糖，鼠李糖，松二糖，纤维二糖，唾液糖(sialose)及其组合。在其它实施方案中，所述至少一种甜味剂不包含碳水化合物甜味剂。
在另一个实施方案中，另外的甜味剂是稀有糖，其选自山梨糖，来苏糖，核酮糖，木糖，木酮糖，D-阿洛糖，L-核糖，D-塔格糖，L-葡萄糖，L-岩藻糖，L-阿拉伯糖，松二糖及其组合。其它甜味剂包括赛门苷I，莫纳甜(monatin)及其盐(莫纳甜SS，RR，RS，SR)，仙茅甜蛋白，甘草酸及其盐，索马甜(thaumatin)，莫内甜蛋白(monellin)，马槟榔甜蛋白(mabinlin)，巴西甜蛋白(brazzein)，坦马汀(tamatin)，甜舌草素(hemandulcin)，叶甜素(phyllodulcin)，菝葜苷(glycyphyllin)，三叶苷，白元参苷，奥斯拉丁(osladin)，多糖苷A(polypodoside A)，蝶卡苷A(pterocaryoside A)，蝶卡苷B，木库罗齐苷(mukurozioside)，糙苏苷I(phlomisoside I)，巴西甘草甜素I(periandrin I)，相思子三萜苷A(abrusosideA)，甜菊双糖苷和青钱柳苷I(cyclocarioside I)，糖醇例如赤藓糖醇，三氯蔗糖，乙酰磺胺酸钾，乙酰磺胺酸及其盐，阿斯巴甜，阿力甜，糖精及其盐，橙皮苷二氢查耳酮葡糖苷，新橙皮苷二氢查耳酮，环己基氨基磺酸盐(cyclamate)，环己基氨基磺酸及其盐，纽甜，爱德万甜，葡糖基化甜菊糖苷(GSG)及其组合。
在一个实施方案中，所述甜味剂为热量甜味剂或热量甜味剂的混合物。在另一个实施方案中，该热量甜味剂选自蔗糖，果糖，葡萄糖，高果糖玉米/淀粉糖浆，甜菜糖，蔗糖及其组合。
在其它实施方案中，所述甜味剂包含至少一种甜菊糖苷，其中所述至少一种甜菊糖苷以增甜量存在。甜菊糖苷可以为天然的，合成的或天然和合成的组合。可以以纯的形式或作为混合物的组成部分提供甜菊糖苷，即甜菊糖苷共混物。示例性甜菊糖苷包括但不限于瑞鲍迪苷M，瑞鲍迪苷D，瑞鲍迪苷A，瑞鲍迪苷N，瑞鲍迪苷O，瑞鲍迪苷E，甜菊单糖苷，甜菊双糖苷，甜茶苷，杜克苷B，杜克苷A，瑞鲍迪苷B，瑞鲍迪苷G，甜菊苷，瑞鲍迪苷C，瑞鲍迪苷F，瑞鲍迪苷I，瑞鲍迪苷H，瑞鲍迪苷L，瑞鲍迪苷K，瑞鲍迪苷J，瑞鲍迪苷M2，瑞鲍迪苷D2，瑞鲍迪苷S，瑞鲍迪苷T，瑞鲍迪苷U，瑞鲍迪苷V，瑞鲍迪苷W，瑞鲍迪苷Zl，瑞鲍迪苷Z2，瑞鲍迪苷IX，酶促葡糖基化甜菊糖苷及其组合。
甜菊糖苷共混物甜味剂典型地具有基于干重约95％重量或更高的总甜菊糖苷含量。其余的5％包含其它非-甜菊糖苷化合物，例如来自提取或纯化过程的副产物。在一些实施方案中，甜菊糖苷共混物甜味剂具有约96％或更高，约97％或更高，约98％或更高或约99％或更高的总甜菊糖苷含量。如本文所用，“总甜菊糖苷含量”是指样品中每种甜菊糖苷的相对重量贡献的总和。
在一个实施方案中，所述甜味剂包含至少一种罗汉果苷，其中所述至少一种罗汉果以增甜量存在。罗汉果苷可以为天然的，合成的或天然和合成的组合。可以以纯的形式或作为混合物的组成部分提供罗汉果苷。示例性罗汉果苷包括但不限于grosmogroside I，罗汉果苷IA，罗汉果苷IE，1l-氧代罗汉果苷IA，罗汉果苷II，罗汉果苷II A，罗汉果苷II B，罗汉果苷II E，7-氧代罗汉果苷II E，罗汉果苷III，罗汉果苷Hie，1l-氧代罗汉果苷HIE，11-脱氧罗汉果苷III，罗汉果苷IV，罗汉果苷IVA，1l-氧代罗汉果苷IV，1l-氧代罗汉果苷IV A，罗汉果苷V，异罗汉果苷V，1l-脱氧罗汉果苷V，7-氧代罗汉果苷V，11-氧代罗汉果苷V，异罗汉果苷V，罗汉果苷VI，罗汉果醇，1l-氧代罗汉果醇，赛门苷I及其组合的任一种。
本文所述的所述至少一种甜味剂与所述至少一种咖啡酰奎尼酸或委陵菜酸化合物的重量比可以变化。
产品
根据本公开，可以将来自须药藤的提取物或级分或一种或多种咖啡酰奎尼酸和委陵菜酸化合物加入到增甜的消费品(即其中具有至少一种甜味剂的消费品)中，或可以作为用于消费品的香料组合物的组成部分提供。
根据本公开，香料组合物可以包括特征性香料和至少一种咖啡酰奎尼酸和委陵菜酸化合物。术语“特征性香料”是指个体食用时被个体感知为占优势的香料。
在一个实施方案中，本文所述的来自须药藤的提取物或级分或一种或多种咖啡酰奎尼酸和委陵菜酸化合物以一定量存在于香料组合物中，该量使得在将香料组合物加入到增甜的消费品中时，与不存在所述来自须药藤的提取物或级分或所述一种或多种咖啡酰奎尼酸和委陵菜酸化合物的消费品相比，所述消费品的蔗糖当量增加。
当加入到消费品中时，所述来自须药藤的提取物或级分或所述一种或多种咖啡酰奎尼酸和委陵菜酸化合物以有效改良甜味剂的甜度或口感但不显示出任何异味的量使用。根据某些实施方案，存在于消费品中的所述来自须药藤的提取物或级分或所述一种或多种咖啡酰奎尼酸和委陵菜酸化合物的量可以为约0.01ppm至约100ppm的浓度，在另一个实施方案中，为约0.01ppm至约50ppm，例如约0.01ppm至约45ppm，约0.01ppm至约40ppm，约0.01ppm至约35ppm，约0.01ppm至约30ppm，约0.01ppm至约25ppm，约0.01ppm至约20ppm，约0.01ppm至约15ppm，约0.01ppm至约10ppm和约0.01ppm至约5ppm。
在一个实施方案中，本文所述的所述至少一种甜味剂以约50ppm至约600ppm，例如约50ppm至约500ppm，约50ppm至约400ppm，约50ppm至约300ppm，约50ppm至约300ppm，约50ppm至约200ppm，约50ppm至约100ppm，约100ppm至约600ppm，约100ppm至约500ppm，约100ppm至约400ppm，约100ppm至约300ppm，约100ppm至约200ppm，约200ppm至约600ppm，约200ppm至约500ppm，约200ppm至约400ppm，约200ppm至约300ppm，约300ppm至约600ppm，约300ppm至约500ppm，约300ppm至约400ppm，约400ppm至约600ppm，约400ppm至约500ppm和约500ppm至约600ppm的浓度存在于消费品中。在另一个实施方案中，对于全糖和低糖应用，所述至少一种甜味剂可以以至多100,000ppm的浓度存在于消费品中。
当表示为“ppm”时，该浓度是基于该消费品的总重按重量计的百万分率。应当理解，当在本公开中描述值的范围时，旨在将该范围内的任何和每个值(包括端点)视为已经公开。例如，所述来自须药藤的提取物或级分或所述一种或多种咖啡酰奎尼酸和委陵菜酸化合物的“0.01ppm至100ppm的范围”应理解解读为指示0.01至100之间的连续体中的每一个可能的数值。应当理解，本发明人认识到并理解，该范围内的任何和所有值被认为已被指定，并且本发明人拥有整个范围和该范围内的所有值。
香料组合物还可以包含一种或多种食品级赋形剂。用于香料组合物的合适赋形剂是本领域众所周知的，并且包括例如但不限于溶剂(包括水，醇，乙醇，油，脂肪，植物油和miglyol)，粘合剂，稀释剂，崩解剂，润滑剂，矫味剂，着色剂，防腐剂，抗氧化剂，乳化剂，稳定剂，增味剂，甜味剂，防结块剂等。用于香料的这类载体或稀释剂的实例可以在如下文献中找到，例如"Perfume and Flavour Materials of Natural Origin"，S.Arctander，Ed.，Elizabeth，N.J.，1960；"Perfume and Flavor Chemicals"，S.Arctander，Ed.，第I&II卷，Allured Publishing Corporation，Carol Stream，USA，1994；"Flavourings"，E.Ziegler和H.Ziegler(ed.)，Wiley-VCH Weinheim，1998，和"CTFA Cosmetic IngredientHandbook"，J.M.Nikitakis(ed.)，第1版，The Cosmetic，Toiletry and FragranceAssociation，Inc.，Washington，1988。
香料组合物可以具有任何合适的形式，例如液体或固体，湿的或干燥的，或以结合或涂覆在载体/颗粒上的包封形式或作为粉末。香料组合物可以包含按香料组合物的重量计约0.01至约10％，在另一个实施方案中约0.01至约5％，在另一个实施方案中约0.01至约1％，或该范围内的任何单个数值的量的特征性香料。在另一个实施方案中，消费品可以包括约0.001至约0.5％的量的特征性香料。在另一个实施方案，约0.01至约0.3％，在另一个实施方案中，约0.02至约0.1％，或该范围内的任何单个数值。
在本公开中，与数值结合使用的术语“约”包括所述值并且具有上下文所规定的含义。例如，它至少包括与特定值的测量相关联的误差程度。本领域普通技术人员将理解，术语“约”在本文中用于表示所述值的“约”的量在本公开的组合物和/或方法中产生所需程度的有效性。本领域普通技术人员将进一步理解，在一个实施方案中，关于任何成分的百分比，量或数量的值的“约”的界限和边界可以通过改变该值，确定每个值的组合物或方法的有效性，并确定产生具有根据本公开的所需有效性程度的组合物或方法的值的范围来确定。
消费品可以包括基料。如本文所用，术语“基料”是指消费品所必需的所有成分，咖啡酰奎尼酸和委陵菜酸化合物除外。根据消费品或添加剂的性质和用途，这些将在性质和比例上自然变化，但它们都是本领域众所周知的，并且可以以本领域公认的比例使用。因此，用于每种可想到的目的的这种基料的制剂在本领域的普通技术范围内。
非限制性地并且仅作为示例的方式，合适的基料可以包括消结块剂，消泡剂，抗氧化剂，粘合剂，着色剂，稀释剂，崩解剂，乳化剂，包封剂或制剂，酶，脂肪，增味剂，矫味剂，树胶，多糖，防腐剂，蛋白质，增溶剂，溶剂，稳定剂，糖衍生物，表面活性剂，甜味剂，维生素，蜡等。可以使用的溶剂是本领域技术人员已知的，并且包括例如水，乙醇，乙二醇，丙二醇，甘油和三醋精。包封剂和树胶包括麦芽糖糊精，阿拉伯树胶，褐藻胶，明胶，改性淀粉，其它多糖和蛋白质。
用于香料化合物的赋形剂，载体，稀释剂或溶剂的实例可以在如下文献中找到，例如“Perfume and Flavour Materials of Natural Origin”，S.Arctander，Ed.，Elizabeth，N.J.，1960；“Perfume and Flavour Chemicals”，S.Arctander，Ed.，第I&II卷，Allured Publishing Corporation，Carol Stream，USA，1994；“Flavourings”，E.Ziegler和H.Ziegler(ed.)，Wiley-VCH Weinheim，1998，和“CTFA Cosmetic IngredientHandbook”，J.M.Nikitakis(ed.)，第1版，The Cosmetic，Toiletry and FragranceAssociation，Inc.，Washington，1988。
合适的香料提供成分的非限制性实例包括天然香料，人造香料，调味品，调味料等。这些包括合成香料油和调味芳香剂和/或油，油树脂，精油和馏出物及其组合。
可以存在辅助成分以提供其它有益效果，例如增强的稳定性，易于掺入消费品或添加剂中以及增强的营养价值。这类辅助成分的非限制性典型实例包括稳定剂，乳化剂，防腐剂，树胶，淀粉，糊精，维生素和矿物质，功能性成分，盐，抗氧化剂和多不饱和脂肪酸。具体实例是可用于喷雾干燥方法的乳化剂和载体。这些的非限制性实例是改性淀粉，例如Capsul.TM.和麦芽糖糊精。
添加剂可以是单一成分或成分的共混物，或者它可以包封在任何合适的包封剂中。添加剂可以通过任何合适的方法制备，例如喷雾干燥，挤出和流化床干燥。
根据本公开，术语“消费品”是指用于受试者出于享受，营养或健康和保健益处目的中的至少一种而典型地经由口腔(尽管可经由非口服手段如吸入进行食用)食用的产品。消费品可以以任何形式存在，包括但不限于液体，固体，半固体，片剂，胶囊，锭剂，条带，粉末，凝胶，树胶，糊剂，浆液，溶液，悬浮液，糖浆，气雾剂和喷雾剂。该术语还指例如膳食和营养以及健康和保健补充剂。消费品包括在丢弃之前在口腔内放置一段时间期限但不吞咽的组合物。它可以在食用之前放入口中，或者可以在丢弃之前在口中保持一段时间期限。
广泛地，消费品包括但不限于所有种类的食物，糖果产品，烘焙产品，甜味产品，美味产品，发酵产品，乳制品，非乳制品，饮料，营养保健制品和药物。
消费品的非限制性实例包括：湿/液体汤，无论浓度或容器如何，包括冷冻汤。出于该定义的目的，汤是指由肉，家禽，鱼，蔬菜，谷物，水果和其它成分制备的食物，在液体中烹饪，其可包括一些或所有这些成分的可见碎片。它可以是澄清的(作为肉汤)或稠的(作为杂烩)，平滑的，泥状的或大块的，即食的，半浓缩的或浓缩的，并且可以是热的或冷的，作为第一道菜或作为主道菜，或者可以作为膳食或作为餐间零食(像饮料一样啜饮)，汤可以用作制备其它膳食组分的成分，并且范围可以从肉汤(清汤)到调味汁(基于奶油或奶酪的汤)；脱水和烹饪食品，包括烹饪助剂产品，例如：粉末，颗粒，糊剂，浓缩液体产品，包括浓缩肉汤，肉汤和肉汤样产品，以压制方块，片剂或粉末或颗粒形式，其作为成品或作为产品，调味汁和配方混合物中的成分单独销售(无论技术如何)；膳食溶液产品，例如：脱水和冷冻干燥汤，包括脱水汤混合物，脱水速溶汤，脱水即煮汤，现成菜肴的脱水或环境制备物，膳食和单份主菜，包括面食，马铃薯和米饭菜肴；膳食装饰产品，例如：调味品，腌泡汁，色拉调味汁，色拉浇头，蘸料，面包屑，面糊混合物，货架稳定涂抹料，烧烤酱汁，液体配方混合物，浓缩物，调味汁或调味汁混合物，包括用于色拉的配方混合物，作为成品或作为产品内的成分出售，无论是脱水的，液体的还是冷冻的；饮料，包括饮料混合物和浓缩物，包括但不限于酒精和非酒精即饮和干粉饮料，碳酸和非碳酸饮料，例如苏打水，果汁或蔬菜汁，酒精和非酒精饮料，茶如绿茶和红茶，葡萄酒如红酒；糖果产品，例如蛋糕，曲奇，派，糖果，口香糖，明胶，冰淇淋，冰冻果子露，布丁，果酱，果冻，色拉调味汁和其它调味品，谷物和其它早餐食品，罐装水果和水果酱等。
提供了增强消费品的甜度和/或调节甜味剂的一种或多种味道属性以使消费味道更像蔗糖增甜的消费品的方法。
在一个实施方案中，增强消费品的甜度的方法包括：(i)提供包含至少一种甜味剂的消费品，和(ii)向所述消费品中添加来自须药藤的提取物或级分或一种或多种咖啡酰奎尼酸和委陵菜酸化合物以提供具有增强的甜度的消费品。
在另一个实施方案中，增强消费品的甜度的方法包括：(i)提供消费品基料，和(ii)向所述消费品基料中添加至少一种甜味剂和来自须药藤的提取物或级分或一种或多种咖啡酰奎尼酸和委陵菜酸化合物以提供具有增强的甜度的消费品。所述至少一种甜味剂和所述来自须药藤的提取物或级分或所述一种或多种咖啡酰奎尼酸和委陵菜酸化合物可以以香料的形式一起加入，或者单独加入。
参考以下非限制性实施例进一步描述本公开。
实施例
以下实施例仅出于示例的目的给出，并且不应被解释为对本发明的限制，因为在不脱离本公开的精神和范围的情况下，本发明的许多变化是可能的。
实施例1：须药藤提取物和级分的制备
将须药藤粉末(200g)加载到66mL不锈钢池(2或3个池，取决于材料密度)上。DionexTM ASETM 350加速溶剂提取器(ASE)的条件设置为：压力1500psi；温度100℃；静置时间15min；循环2；冲洗70％；吹扫60s。依次用100％和80％甲醇提取每个池。合并所有提取物，并在旋转蒸发器上蒸发有机溶剂，得到42g萃取物。将旋转蒸发器后的提取物冷冻干燥。
HP-20用于对植物提取物进行分级。在Biotage快速色谱系统上研发了自动HP-20分级方法。简言之，使100g HP-20吸收性树脂上25mm×500mm柱并用甲醇洗涤。HP-20柱用水平衡。将10g植物提取物悬浮于水中并超声处理20min。然后使该悬浮液上柱。使用以下流动相：0％甲醇水溶液350mL，30％甲醇450mL，50％甲醇450mL，70％和100％MeOH550mL。将流速设定为4mL/min。在254nm下监测UV信号以确保分级一致性。每个级分为225mL(240mL收集瓶)。将每两个级分合并，得到最终的五个级分(0，30％，50％，70％，100％MeOH级分)。分级后，将0，30％和50％MeOH级分送至TurboVap以除去溶剂。使用旋转蒸发器蒸发70％和100％MeOH级分。将全部五个级分最终在冷冻干燥器上冻干。
实施例2：来自须药藤的化合物的表征
在Waters ACQUITY H-Class UPLC-Synapt G2-Si系统(Waters，USA)上进行化学分析。在25℃下使用UPLC C18分析柱(2.1mm×150mm，I.D.，1.8μm，ACQUITYHSST3，Waters，USA)。水(A)和乙腈(B)(均包含0.1％甲酸)用作流动相，线性梯度编程如下：0-30min，5％B；30-45min，90％B；45-46min，B％；46-50min，5％B。流速设定为0.8mL.min-1，且注射体积为2μL。质谱仪配备有电喷雾电离(ESI)源，并且通过从m/z 100至1500扫描以正模式获得数据。MS分析如下操作：去溶剂化气体流速，800L/hr；去溶剂化温度300℃；雾化器气流，6.5Bar；毛细管电压，3000V；源温度，80℃；采样锥形电压，40V。扫描时间设定为0.2s。通过在质谱仪中以10μL/min的流速输注400ng/mL亮氨酸-脑啡肽溶液，通过lockspray界面进行内部校准。将lockspray扫描时间和频率分别设定为0.5s和15s。该系统由Masslynx 4.1(Waters)控制。在没有前体选择的情况下，在MSE模式中在m/z范围50-1500内使用在低(10eV)和高(20-120eV斜坡)碰撞能量下0.2s的交替扫描，获得数据。
表I
来自须药藤的级分中的化合物的表征
表II
星型三萜苷I，J和K的1H-和13C-NMR光谱数据(在吡啶-d5中)
/>
/>
实施例3：使用须药藤级分的调味
制备来自须药藤的HP-20的水级分，并在不同应用中使用不同量的提取物进行描述性感官评价。与不存在所述须药藤级分的相同应用相比，该分析的结果如表III中所示。
表III
/>
尽管已经示例和描述了本发明的具体实施方案，但是对于本领域技术人员显而易见的是，在不脱离本发明的精神和范围的情况下，可以进行各种其它改变和变型。因此，预期在所附权利要求中覆盖在本发明范围内的所有这些改变和变型。
Claims (15)
1.消费品，包含：
(a)至少一种甜味剂，和
(b)甜度改良剂，其包含来自须药藤的提取物或级分或至少一种咖啡酰奎尼酸或委陵菜酸化合物，
其中所述至少一种甜味剂以增甜量存在。
2.权利要求1的消费品，其中所述至少一种甜味剂选自蔗糖，果糖，葡萄糖，木糖，阿拉伯糖，鼠李糖，塔格糖，阿卢糖，海藻糖，异麦芽酮糖，甜菊糖苷，罗汉果苷，甜菊糖，三叶苷，甜茶苷，阿斯巴甜，爱德万甜，龙舌兰糖浆，乙酰磺胺酸钾(AceK)，高果糖玉米糖浆，纽甜，糖精，三氯蔗糖，高果糖玉米糖浆，淀粉糖浆，罗汉果提取物，新橙皮苷二氢查耳酮，柚皮苷二氢查耳酮，HDG，糖醇，纤维二糖，阿洛酮糖，环己基氨基磺酸盐，巴西甜蛋白，坦马汀，糖蜜，大米糖浆及其组合。
3.权利要求2的消费品，其中所述甜菊糖苷选自瑞鲍迪苷M，瑞鲍迪苷D，瑞鲍迪苷A，瑞鲍迪苷N，瑞鲍迪苷O，瑞鲍迪苷E，甜菊单糖苷，甜菊双糖苷，甜茶苷，杜克苷B，杜克苷A，瑞鲍迪苷B，瑞鲍迪苷G，甜菊苷，瑞鲍迪苷C，瑞鲍迪苷F，瑞鲍迪苷I，瑞鲍迪苷H，瑞鲍迪苷L，瑞鲍迪苷K，瑞鲍迪苷J，瑞鲍迪苷M2，瑞鲍迪苷D2，瑞鲍迪苷S，瑞鲍迪苷T，瑞鲍迪苷U，瑞鲍迪苷V，瑞鲍迪苷W，瑞鲍迪苷Zl，瑞鲍迪苷Z2，瑞鲍迪苷IX，酶促葡糖基化甜菊糖苷及其组合。
4.权利要求2的消费品，其中所述罗汉果苷选自grosmogroside I，罗汉果苷IA，罗汉果苷IE，1l-氧代罗汉果苷IA，罗汉果苷II，罗汉果苷II A，罗汉果苷II B，罗汉果苷II E，7-氧代罗汉果苷II E，罗汉果苷III，罗汉果苷Hie，1l-氧代罗汉果苷HIE，11-脱氧罗汉果苷III，罗汉果苷IV，罗汉果苷IVA，1l-氧代罗汉果苷IV，1l-氧代罗汉果苷IV A，罗汉果苷V，异罗汉果苷V，1l-脱氧罗汉果苷V，7-氧代罗汉果苷V，11-氧代罗汉果苷V，异罗汉果苷V，罗汉果苷VI，罗汉果醇，1l-氧代罗汉果醇，赛门苷I及其组合。
5.权利要求1的消费品，其中所述甜度改良剂以0.01ppm至100ppm的浓度存在。
6.权利要求1的消费品，其中所述至少一种咖啡酰奎尼酸化合物选自5-O-咖啡酰奎尼酸，3-O-咖啡酰奎尼酸，4-O-c酸，4,5-二-O-咖啡酰奎尼酸，3,5-二-咖啡酰奎尼酸，3,4-二-O-咖啡酰奎尼酸及其组合。
7.权利要求1的消费品，其中所述消费品为饮料。
8.权利要求1的消费品，其中所述提取物或级分包括至少一种咖啡酰奎尼酸或委陵菜酸化合物。
9.权利要求1的消费品，其中所述至少一种咖啡酰奎尼酸或委陵菜酸化合物分离自所述须药藤提取物或级分。
10.香料组合物，包含来自须药藤的提取物或级分或至少一种分离自所述须药藤提取物或级分的咖啡酰奎尼酸或委陵菜酸化合物。
11.权利要求10的香料组合物，其中至少一种咖啡酰奎尼酸化合物选自5-O-咖啡酰奎尼酸，3-O-咖啡酰奎尼酸，4-O-c酸，4,5-二-O-咖啡酰奎尼酸，3,5-二-咖啡酰奎尼酸，3,4-二-O-咖啡酰奎尼酸及其组合。
12.权利要求10的香料组合物，为乳液形式。
13.权利要求10的香料组合物，为粉末形式。
14.增强包含甜味剂的消费品的甜度或口感的方法，包括以有效改良所述消费品的甜度或口感的量向所述消费品中添加来自须药藤的提取物或级分或至少一种咖啡酰奎尼酸或委陵菜酸化合物。
15.香料组合物，包含选自下组的化合物：3-没食子酰基奎尼酸，5-O-没食子酰基奎尼酸，星型三萜苷E，F和G，星型三萜苷I(3-O-β-D-吡喃葡萄糖基-28-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2α,3β-二羟基-乌苏-12-烯-28-酸)，星型三萜苷J(3-O-β-D-吡喃葡萄糖基-28-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2α,3β,19α-三羟基-乌苏-12-烯-28-酸)，星型三萜苷K(3-O-β-D-吡喃葡萄糖基-28-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖基-2α,3β-二羟基-齐墩果-12-烯-28-酸)及其组合。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063126907P | 2020-12-17 | 2020-12-17 | |
| US63/126,907 | 2020-12-17 | ||
| PCT/EP2021/086014 WO2022129240A1 (en) | 2020-12-17 | 2021-12-15 | Compositions and methods for taste modulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116583192A true CN116583192A (zh) | 2023-08-11 |
Family
ID=79317155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180085140.1A Pending CN116583192A (zh) | 2020-12-17 | 2021-12-15 | 用于调味的组合物和方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230389588A1 (zh) |
| EP (1) | EP4262434A1 (zh) |
| JP (1) | JP2024502412A (zh) |
| KR (1) | KR20230119182A (zh) |
| CN (1) | CN116583192A (zh) |
| AU (1) | AU2021399865A1 (zh) |
| CA (1) | CA3203818A1 (zh) |
| MX (1) | MX2023005945A (zh) |
| WO (1) | WO2022129240A1 (zh) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10492516B2 (en) * | 2010-12-13 | 2019-12-03 | Purecircle Sdn Bhd | Food ingredients from Stevia rebaudiana |
| WO2012107202A1 (en) * | 2011-02-08 | 2012-08-16 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Sweetener, sweetener compositions, methods of making the same and consumables containing the same |
| US20140272068A1 (en) * | 2013-03-14 | 2014-09-18 | Indra Prakash | Beverages containing rare sugars |
| AU2018275568B2 (en) * | 2017-05-31 | 2024-05-02 | The Coca-Cola Company | Sweetness and taste improvement of steviol glycoside and mogroside sweeteners with cyclamate |
| CN115279206A (zh) * | 2020-03-31 | 2022-11-01 | 弗门尼舍有限公司 | 风味剂组合物 |
-
2021
- 2021-12-15 JP JP2023536893A patent/JP2024502412A/ja active Pending
- 2021-12-15 KR KR1020237023532A patent/KR20230119182A/ko unknown
- 2021-12-15 CA CA3203818A patent/CA3203818A1/en active Pending
- 2021-12-15 EP EP21840501.7A patent/EP4262434A1/en active Pending
- 2021-12-15 MX MX2023005945A patent/MX2023005945A/es unknown
- 2021-12-15 WO PCT/EP2021/086014 patent/WO2022129240A1/en active Application Filing
- 2021-12-15 CN CN202180085140.1A patent/CN116583192A/zh active Pending
- 2021-12-15 US US18/039,141 patent/US20230389588A1/en active Pending
- 2021-12-15 AU AU2021399865A patent/AU2021399865A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021399865A9 (en) | 2024-05-16 |
| EP4262434A1 (en) | 2023-10-25 |
| WO2022129240A1 (en) | 2022-06-23 |
| AU2021399865A1 (en) | 2023-08-03 |
| JP2024502412A (ja) | 2024-01-19 |
| US20230389588A1 (en) | 2023-12-07 |
| CA3203818A1 (en) | 2022-06-23 |
| KR20230119182A (ko) | 2023-08-16 |
| MX2023005945A (es) | 2023-06-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6659885B2 (ja) | レバウジオシドｂを含有する甘味料組成物 | |
| CN107404919B (zh) | 甜味剂组合物及含有该组合物的食品 | |
| JP2023522095A (ja) | 組成物 | |
| WO2017189778A1 (en) | Methods, compounds, and compositions, for modulating sweet taste | |
| CA3002583C (en) | Method of masking off-tastes with cellobiose and/or psicose | |
| CN112601461B (zh) | 作为甜度增强剂的多甲氧基黄酮 | |
| JP2018531030A6 (ja) | セロビオースおよび／またはプシコースで、オフテイストをマスキングする方法 | |
| CN106659204B (zh) | 甜味剂组合物 | |
| CN116583192A (zh) | 用于调味的组合物和方法 | |
| CN116600658A (zh) | 用于调味的组合物和方法 | |
| CN116615115A (zh) | 用于调味的组合物和方法 | |
| JP6910351B2 (ja) | 甘味増強 | |
| WO2023242015A2 (en) | Compositions containing brazzein | |
| WO2024041991A1 (en) | Compositions comprising aromadendrin 3-acetate | |
| WO2023049850A2 (en) | Uses of musk compounds in flavors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |