CN116577490B - Efficient blood coagulation and platelet function analyzer and analysis method thereof - Google Patents
Efficient blood coagulation and platelet function analyzer and analysis method thereof Download PDFInfo
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- CN116577490B CN116577490B CN202310848101.3A CN202310848101A CN116577490B CN 116577490 B CN116577490 B CN 116577490B CN 202310848101 A CN202310848101 A CN 202310848101A CN 116577490 B CN116577490 B CN 116577490B
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- 238000012360 testing method Methods 0.000 claims abstract description 69
- 238000001514 detection method Methods 0.000 claims abstract description 43
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- 238000007789 sealing Methods 0.000 claims abstract description 11
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
- G01N11/16—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention relates to the technical field of analyzers and provides a high-efficiency blood coagulation and platelet function analyzer and an analysis method thereof, wherein the high-efficiency blood coagulation and platelet function analyzer comprises an analyzer body and a positioning frame, the top of the analyzer body is fixedly connected with a heat preservation frame, the top of the heat preservation frame is fixedly connected with a rubber pad, a high-efficiency detection assembly is arranged in the heat preservation frame, a blood sample test cup is arranged in the high-efficiency detection assembly, the side end of the positioning frame is fixedly connected with a second reset spring, the other end of the second reset spring is fixedly connected with a clamping rod, the clamping rod penetrates through the side end of the positioning frame and is fixedly connected with a traction rope, and the other end of the traction rope is fixedly connected with a connecting ring. Through above-mentioned technical scheme, the problem that coagulation and platelet function analysis appearance among the prior art can not carry out automatic stable extrusion fixed and dismantlement to the test cup and break away from the work to can not carry out automatic stable sealing treatment to the test cup is solved.
Description
Technical Field
The invention relates to the technical field of analyzers, in particular to a high-efficiency blood coagulation and platelet function analyzer and an analysis method thereof.
Background
The blood is a liquid tissue flowing in blood vessels, the blood consists of blood cells and blood plasma, the blood cells comprise three cells, namely red blood cells, white blood cells and platelets, wherein the red blood cells are the cell type with the largest number, the red blood cells contain hemoglobin, the hemoglobin contains heme, the process of changing the flowing liquid state into a non-flowing gel state is an important link of physiological hemostasis, the essence of blood coagulation is the process of changing the soluble fibrinogen in the blood plasma into the non-soluble fibrin, and the characteristic change of viscosity and elasticity is shown in the process of changing the blood from the liquid state into the gel state and finally into the gel state, so that the blood sample of a patient can be detected and analyzed by using a blood coagulation and platelet function analyzer in the cardiovascular operation and anticoagulation treatment process, and the anticoagulation effect can be accurately reflected, thereby providing objective basis for the use of anticoagulants, and leading the diseases to be diagnosed early and better treated.
The existing blood coagulation and platelet function analyzer has some problems in the use process, for example, the blood coagulation and platelet function analyzer with the model SCP2 is characterized in that a cover plate is turned over and opened, then a test cup is placed in a test cup holder on the analyzer and heated, then a blood sample to be detected is conveyed into the test cup, the cover plate is turned over and closed, after the cover plate is turned over and closed, a sensing detection mechanism in the cover plate can drive a probe to be stably inserted into the blood sample in the test cup, and then the stable detection and analysis work can be carried out on the blood coagulation and platelet function in the blood sample, but the test cup is limited and fixed by friction force in the process of placing the blood sample test cup in a test cup holder, when the friction force is large, workers need to consume a large amount of force to finish the taking and placing work of the blood sample test cup, when the friction force is smaller, the probe is very easy to drive the test cup to shake in the process of detecting the probe motion, and then the detection and analysis result can be influenced, so that the detection and analysis result is inaccurate, the existing blood coagulation and platelet function analyzer can not automatically and stably extrude, fix and detach the test cup to be separated from work, and further can not ensure the stability and convenience of the subsequent detection work, and the existing blood coagulation and platelet function analyzer can not automatically and stably seal the test cup, so that the external environment temperature is very easy to influence the temperature of the blood sample in the test cup, and then the subsequent detection and analysis result can be influenced, moreover, when the cover plate is turned and closed, the existing blood coagulation and platelet function analyzer is not standardized, the collision between the probe and the test cup is very easy to occur due to the fact that the operation of staff is not standardized, the practicability is poor, the detection efficiency is low; the existing blood coagulation and platelet function analyzer is poor in protection performance, after the blood coagulation and platelet function analyzer is finished in operation, the blood coagulation and platelet function analyzer cannot be closed and protected, and in the operation process, the whole blood coagulation and platelet function analyzer cannot be adsorbed and fixed on a workbench surface conveniently and stably, so that in the operation process of operating the analyzer by workers, the analyzer is subjected to touch to shake, and blood samples in a blood sample test cup are easily scattered, and therefore, the requirements of users are met by the efficient blood coagulation and platelet function analyzer and an analysis method thereof are needed.
Disclosure of Invention
The invention provides a high-efficiency blood coagulation and platelet function analyzer and an analysis method thereof, which solve the problems that the blood coagulation and platelet function analyzer in the related art cannot automatically and stably extrude, fix, disassemble and separate a test cup, cannot automatically and stably seal the test cup, and the collision between a probe and the test cup is easily caused by the abnormal operation of a worker, so that the practicability is poor and the detection efficiency is low; and can not fix the whole convenient stable absorption of blood coagulation and platelet function analysis appearance on table surface, the relatively poor problem of security.
The technical scheme of the invention is as follows:
the utility model provides an efficient blood coagulation and platelet function analysis appearance, includes analysis appearance body and locating frame, the top fixedly connected with heat preservation frame of analysis appearance body, the top fixedly connected with rubber pad of heat preservation frame, install high-efficient detection subassembly in the heat preservation frame, be provided with blood sample test cup in the high-efficient detection subassembly, the side fixedly connected with second reset spring of locating frame, the other end fixedly connected with kelly of second reset spring, the kelly runs through sliding connection and is in the side of locating frame, the one end fixedly connected with haulage rope of kelly, the other end fixedly connected with go-between of haulage rope, the other end block of kelly is connected in the draw-in groove, the side at the magnet lid is seted up to the draw-in groove, be provided with magnet body in the magnet lid, the bottom of magnet body is provided with the coil fixing base, the bottom fixedly connected with coil body of coil fixing base, the bottom fixedly connected with first spacer post of second reset spring, the bottom of first spacer post is provided with the first elastic piece, the bottom of vibration isolation post is connected with the elastic piece, the vibration isolation post is installed to the bottom of vibration post is fixed with the vibration column, the vibration isolation post is installed the bottom of vibration isolation post is fixed with the vibration column.
As a preferred embodiment of the present invention, wherein: the efficient detection assembly comprises a fixing sleeve, the bottom end of the fixing sleeve is fixedly connected to the inner bottom end face of the heat preservation frame, a strong spring is fixedly connected to the inner bottom end face of the fixing sleeve, a first rubber piston is fixedly connected to the top end of the strong spring, the first rubber piston is in limiting sliding connection with the fixing sleeve, a first plug rod is fixedly connected to the top end of the first rubber piston, a connecting baffle is fixedly connected to the top end of the first plug rod, the central axis of the fixing sleeve and the central axis of the heat preservation frame are located on the same vertical central line, the top end face of the heat preservation frame and the top end face of the fixing sleeve are flush, the cross section of the fixing sleeve is rectangular, the inner wall of the fixing sleeve is in contact with the side end face of the first rubber piston, the first plug rod is fixed to the bottom central part of the connecting baffle, and the length and the width of the connecting baffle are respectively larger than the length and the width of the cross section of the heat preservation frame.
As a preferred embodiment of the present invention, wherein: the novel plug rod is characterized in that a first reset spring is fixedly connected in the first plug rod, the other end of the first reset spring is fixedly connected with a push rod, the push rod is in the first plug rod in a limiting sliding mode, a fixed rod is fixedly connected in the fixed sleeve, a sliding rod is connected to the fixed rod in a limiting sliding mode, the first reset springs are symmetrically distributed on two sides of the first plug rod, the first reset springs are in one-to-one correspondence with the push rods, the cross sections of the end portions of the push rods are right-angled triangles, the end portions of the fixed rod are inclined, and the cross sections of the end portions of the sliding rod are isosceles triangles.
As a preferred embodiment of the present invention, wherein: the bottom side end of fixed sleeve is connected with the air duct, the other end of air duct is connected with the rubber gasbag, rubber gasbag fixed connection is in the heat conduction frame, install electric heating wire in the heat conduction frame, the bottom fixed connection of heat conduction frame is in on the inside bottom end face of heat preservation frame, the bottom of connecting baffle with the top fixed connection of locating frame, the bottom end face of connecting baffle with magnet cover's top end laminating mutually, the air duct symmetric distribution is in fixed sleeve's bottom both sides, the air duct passes through rubber gasbag with the heat conduction frame one-to-one, rubber gasbag with the heat conduction frame is cylindric, electric heating wire equidistance distributes in the heat conduction frame.
As a preferred embodiment of the present invention, wherein: the diameter of the blood sample test cup is smaller than the inner diameter of the heat conduction frame, the depth of the heat conduction frame is smaller than the depth of the blood sample test cup, the diameter of the blood sample test cup is smaller than the bottom diameter of the sealing cylinder, and the sealing cylinder is fixed at the middle part of the bottom of the vibration spring plate cover.
As a preferred embodiment of the present invention, wherein: the inner diameter of the positioning frame is larger than the diameter of the magnet cover, the second reset spring is sleeved on the clamping rods, the clamping rods are symmetrically distributed on two sides of the positioning frame, the clamping rods are in one-to-one correspondence with the traction ropes, the traction ropes are fixed at the center parts of the end parts of the clamping rods, and the traction ropes penetrate through the connecting baffle plates in a sliding connection mode.
As a preferred embodiment of the present invention, wherein: the multifunctional protection assembly comprises a fixed pipe, the fixed pipe is fixedly connected in the fixed base, the filter screen plate is fixedly connected in the fixed pipe, the second rubber piston is fixedly connected in the fixed pipe in a limiting sliding manner, the third reset spring is fixedly connected on the second rubber piston, the fixed pipe is symmetrically distributed on two sides inside the fixed base, the filter screen plate is symmetrically distributed on two sides inside the fixed pipe, and the side end face of the fixed pipe, the side end face of the filter screen plate and the side end face of the fixed base are flush.
As a preferred embodiment of the present invention, wherein: the second rubber piston is fixedly connected with a second plug rod, the other end of the second plug rod is fixedly connected with a protection frame, the second plug rod penetrates through the filter screen plate and is connected with an electromagnet in a sliding mode, the second plug rod is fixed at the middle of the second rubber piston, and the inner wall of the protection frame is respectively attached to the outer end face of the fixing base and the outer end face of the analyzer body.
As a preferred embodiment of the present invention, wherein: the bottom of fixed pipe is connected with first connecting pipe, the bottom of first connecting pipe is connected with the second connecting pipe, the bottom of second connecting pipe is connected with rubber sucking disc, second connecting pipe fixed connection is in the unable adjustment base, the fixed pipe passes through first connecting pipe with second connecting pipe one-to-one, first connecting pipe is connected the bottom middle part of fixed pipe, rubber sucking disc equidistance distributes the bottom of second connecting pipe, rubber sucking disc bottom surface highly be less than the height of unable adjustment base bottom surface.
An efficient method for blood coagulation and platelet function analysis comprising the steps of:
s1: the analyzer body is placed on the workbench surface, and the multifunctional protection component is started, so that the analyzer body can be automatically adsorbed and fixed on the workbench surface by the multifunctional protection component;
s2: the blood sample can be conveyed into the blood sample test cup after being preheated to 37 degrees by placing the blood sample test cup in the high-efficiency detection assembly for preheating;
s3: the high-efficiency detection assembly is driven to automatically position and fix the blood sample test cup, and the probe can be inserted into the central part of the blood sample test cup;
S4: the coil body is positioned in a constant magnetic field generated by the magnet body, and interaction force exists between the magnetic field generated by the current and the magnetic field generated by the magnet body; the coil body is fixed on an elastic structure formed by the two vibrating spring plate bodies, and the coil is pushed/pulled to move simultaneously due to the change of magnetic force, so that the elastic structure is subjected to the action of magnetic force and elastic force to reciprocate, and a vibrating column is fixed on the elastic structure, so that the probe can be driven to contact with blood and reciprocate under the driving of the vibrating column; when the probe reciprocates in the tested substance, the sensor senses the change of blood viscosity, the change of voltage is converted into the change of blood coagulation signal, the electric signal is converted into a digital signal, and the digital signal is depicted on the display screen of the analyzer body, so that the detection and analysis work of the functions of coagulation and blood platelets is completed.
The working principle and the beneficial effects of the invention are as follows:
1. the high-efficiency detection assembly is arranged in the invention, the connecting baffle can be conveniently and stably closed and opened under the cooperation of the ejector rod, the fixed rod and the sliding rod, and the connecting baffle can drive the probe to conveniently and stably move in the vertical direction under the guiding action of the fixed sleeve and the first plug rod, so that the problem that collision occurs between the flip cover and the blood sample test cup in the process of overturning and closing the probe can be effectively avoided, and the first rubber piston at the bottom of the first plug rod can automatically inflate the rubber air bag when the connecting baffle moves downwards to close, so that the blood sample test cup can be conveniently and stably extruded and fixed, the problem that the follow-up detection result is influenced by the blood sample test cup driven by blood in the reciprocating motion process of the probe can be effectively avoided, and in the same way, the rubber air bag can be automatically reset when the connecting baffle moves upwards to open, so that the follow-up taking and placing work of the blood sample test cup can be ensured, and the use diversity and convenience of the analyzer can be effectively improved.
The rubber pad and the sealing cylinder are arranged in the invention, when the connecting baffle plate moves downwards to close, the heat preservation frame can be automatically and stably sealed and closed through the rubber pad, meanwhile, the vibration spring plate cover can be automatically and stably sealed and closed on the blood sample test cup through the sealing cylinder, and further, the adverse effect of the external environment temperature on the temperature of the blood sample in the blood sample test cup can be effectively avoided, so that the accuracy of the follow-up detection result can be ensured.
The clamping rod and the clamping groove are arranged in the invention, under the cooperation of the clamping rod and the clamping groove, the magnet cover can be conveniently and stably detached and installed by combining the positioning frame, so that the sensing detection head consisting of the magnet cover, the magnet body, the magnet reflecting sheet, the coil body, the coil fixing seat, the first elastic sheet isolation column, the second elastic sheet isolation column, the vibration elastic sheet body, the vibration elastic sheet cover, the vibration column and the probe can be conveniently and stably detached and installed, and therefore, the sensing detection head can be conveniently and stably overhauled and maintained or replaced, and the stability of the long-time working state of the analyzer is ensured.
The multifunctional protection assembly is arranged in the analyzer, the protection frames on two sides can be stably closed by utilizing the magnetic adsorption of the electromagnet, so that the analyzer body in idle operation can be stably protected, when the analyzer body starts to operate, the protection frames on two sides are pushed to move and open, at the moment, under the cooperation of the fixed pipe and the second rubber piston in the second connecting pipe, the internal air of each rubber sucker at the bottom of the second connecting pipe can be sucked, at the moment, the inside of each rubber sucker forms negative pressure, and the whole analyzer body can be automatically and stably adsorbed and fixed on a workbench surface, so that the stability and the safety of the subsequent working state of the analyzer body can be ensured, the problem that a blood sample in a blood sample test cup is inclined and scattered due to touch in the working process of the analyzer body is avoided, and the use diversity and the safety of the analyzer are improved.
Drawings
The invention will be described in further detail with reference to the drawings and the detailed description.
FIG. 1 is a schematic perspective view of the whole structure of the present invention;
FIG. 2 is a schematic view of the connection structure of the protection frame and the electromagnet according to the present invention;
FIG. 3 is a schematic overall front view of the present invention;
FIG. 4 is a schematic diagram of the main sectional structure of the heat preservation frame of the invention;
FIG. 5 is a schematic view of the structure of FIG. 4A according to the present invention;
FIG. 6 is a schematic illustration of a first stopper rod of the present invention in a top-down view;
FIG. 7 is a schematic view of a heat conducting frame of the present invention in a top-down view;
FIG. 8 is a schematic view of a rubber bladder of the present invention in a top-down view;
FIG. 9 is a schematic perspective view of a seal cartridge of the present invention;
FIG. 10 is a schematic view of a positioning frame of the present invention in a main sectional configuration;
FIG. 11 is a schematic diagram of an explosion structure of a vibrating dome body according to the present invention;
FIG. 12 is a schematic view of a vibrating column in semi-section according to the present invention;
FIG. 13 is a schematic view of the main sectional structure of the fixing base of the present invention;
FIG. 14 is a schematic side sectional view of a stationary base of the present invention;
fig. 15 is a schematic view of the structure of fig. 12B according to the present invention.
In the figure: 1. an analyzer body; 2. a heat preservation frame; 3. a rubber pad; 4. an efficient detection assembly; 401. a fixed sleeve; 402. a strong spring; 403. a first rubber piston; 404. a first stopper rod; 405. a connecting baffle; 406. a first return spring; 407. a push rod; 408. a fixed rod; 409. a slide bar; 410. an air duct; 411. a heat conduction frame; 412. a rubber air bag; 413. an electric heating wire; 5. a blood sample test cup; 6. a positioning frame; 7. a second return spring; 8. a clamping rod; 9. a traction rope; 10. a connecting ring; 11. a clamping groove; 12. a magnet cover; 13. a magnet body; 14. a magnet reflection sheet; 15. a coil body; 16. a coil fixing seat; 17. a first spring isolation column; 18. a second spring isolation column; 19. a vibrating spring plate body; 20. a vibrating spring cover; 21. a vibration column; 22. a probe; 23. a fixed base; 24. a multi-functional protective assembly; 2401. a fixed tube; 2402. a screen plate; 2403. a second rubber piston; 2404. a third return spring; 2405. a second stopper rod; 2406. a protective frame; 2407. an electromagnet; 2408. a first connection pipe; 2409. a second connection pipe; 2410. a rubber suction cup; 25. and (5) sealing the cylinder.
Detailed Description
The technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by one of ordinary skill in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
As shown in fig. 1-15, this embodiment provides a high-efficiency blood coagulation and platelet function analyzer, including an analyzer body 1 and a positioning frame 6, the top fixedly connected with heat preservation frame 2 of the analyzer body 1, the top fixedly connected with rubber pad 3 of heat preservation frame 2, install high-efficiency detection subassembly 4 in heat preservation frame 2, be provided with blood sample test cup 5 in the high-efficiency detection subassembly 4, the side fixedly connected with second reset spring 7 of positioning frame 6, the other end fixedly connected with clamping lever 8 of second reset spring 7, clamping lever 8 runs through sliding connection at the side of positioning frame 6, the one end fixedly connected with haulage rope 9 of clamping lever 8, the other end fixedly connected with go-between 10 of haulage rope 9, the other end block connection of clamping lever 8 is in draw-in groove 11, draw-in groove 11 is seted up at the side of magnet lid 12, be provided with magnet body 13 in the magnet lid 12, the bottom of the magnet body 13 is provided with a magnet reflector plate 14, the bottom of the magnet body 13 is fixedly connected with a coil fixing seat 16, a coil body 15 is arranged in the coil fixing seat 16, the bottom of the coil fixing seat 16 is fixedly connected with a first elastic sheet isolating column 17, a second elastic sheet isolating column 18 is arranged in the first elastic sheet isolating column 17, a vibration elastic sheet body 19 is connected to the second elastic sheet isolating column 18, the bottom of the first elastic sheet isolating column 17 is fixedly connected with a vibration elastic sheet cover 20, the bottom of the vibration elastic sheet cover 20 is fixedly connected with a vibration column 21, a probe 22 is arranged in the vibration column 21, the bottom end of the analyzer body 1 is fixedly connected with a fixing base 23, a multifunctional protection component 24 is arranged in the fixing base 23, a sealing cylinder 25 is fixedly connected to the bottom end face of the vibration elastic sheet cover 20, the blood sample test cup 5 can be conveniently and stably extruded and fixed by utilizing the high-efficiency detection component 4, and can avoid flip to drive probe 22 through steady motion and overturn closed motion in-process, take place the problem of colliding with between the blood sample test cup 5, through getting the convenient of putting to blood sample test cup 5, can effectively improve blood detection efficiency, and cooperation rubber pad 3 and sealed section of thick bamboo 25, can carry out automatic stable sealed closure to heat preservation frame 2 and blood sample test cup 5 respectively, and then can effectively avoid external environment temperature to cause harmful effects to blood sample temperature in the blood sample test cup 5, thereby can guarantee follow-up testing result's accuracy, and utilize card pole 8 and draw-in groove 11's cooperation effect down, combine positioning frame 6 can carry out convenient stable dismantlement installation to magnet lid 12, and then can carry out convenient stable dismantlement installation to the sensing head, thereby can carry out convenient stable maintenance or change work to the sensing head, guarantee the stability of the long-time operating condition of analysis appearance, simultaneously can carry out convenient stable protection work to the operating condition and idle state of analysis appearance body 1 respectively through multi-functional protection subassembly 24.
Example 2
As shown in fig. 1 to 15, based on the same concept as that of the above-described embodiment 1, this embodiment also proposes a highly efficient coagulation and platelet function analyzer.
In this embodiment, the high-efficiency detecting component 4 includes a fixed sleeve 401, the bottom end of the fixed sleeve 401 is fixedly connected to the inner bottom end face of the heat insulation frame 2, a strong spring 402 is fixedly connected to the inner bottom end face of the fixed sleeve 401, the top end of the strong spring 402 is fixedly connected with a first rubber piston 403, the first rubber piston 403 is in limited sliding connection with the fixed sleeve 401, the top end of the first rubber piston 403 is fixedly connected with a first plug rod 404, the top end of the first plug rod 404 is fixedly connected with a connecting baffle 405, the central axis of the fixed sleeve 401 and the central axis of the heat insulation frame 2 are located on the same vertical central line, the top end face of the heat insulation frame 2 is flush with the top end face of the fixed sleeve 401, the cross section of the fixed sleeve 401 is rectangular, the inner wall of the fixed sleeve 401 is attached to the side end face of the first rubber piston 403, the first plug rod 404 is fixed at the bottom central position of the connecting baffle 405, the length and the width of the connecting baffle 405 are respectively larger than the length and the width of the cross section of the heat preservation frame 2, a first reset spring 406 is fixedly connected in the first plug rod 404, the other end of the first reset spring 406 is fixedly connected with a push rod 407, the push rod 407 is in limit sliding connection in the first plug rod 404, a fixed rod 408 is fixedly connected in the fixed sleeve 401, a sliding rod 409 is in limit sliding connection on the fixed rod 408, the first reset springs 406 are symmetrically distributed on two sides of the first plug rod 404, the first reset springs 406 are in one-to-one correspondence with the push rod 407, the end section of the push rod 407 is in a right triangle shape, the end section of the fixed rod 408 is in an inclined shape, the end section of the sliding rod 409 is in an isosceles triangle shape, and the connecting baffle 405 can be conveniently and stably closed and opened under the cooperation of the push rod 407, the fixed rod 408 and the sliding rod 409, and under the guiding action of fixed sleeve 401 and first cock stem 404, can drive probe 22 through connecting baffle 405 and carry out convenient stable vertical direction motion, and then can effectively avoid flip to drive probe 22 and overturn closed motion in-process, take place the problem of colliding with between the blood sample test cup 5.
In this embodiment, the bottom side of fixed sleeve 401 is connected with air duct 410, the other end of air duct 410 is connected with rubber gasbag 412, rubber gasbag 412 fixed connection is in heat conduction frame 411, install electric heater strip 413 in heat conduction frame 411, the bottom fixed connection of heat conduction frame 411 is on the inside bottom end face of heat preservation frame 2, the bottom of connection baffle 405 and the top fixed connection of locating frame 6, the bottom face of connection baffle 405 is laminated with the top face of magnet lid 12, air duct 410 symmetric distribution is in the bottom both sides of fixed sleeve 401, air duct 410 passes through rubber gasbag 412 and heat conduction frame 411 one-to-one, rubber gasbag 412 and heat conduction frame 411 are cylindric, electric heater strip 413 equidistance distributes in heat conduction frame 411, when connection baffle 405 downstream closes, through the first rubber piston 403 of first cock stem 404 bottom can carry out automatic charging to rubber gasbag 412, and then can carry out convenient stable extrusion fixed to blood sample cup 5, thereby can effectively avoid probe 22 reciprocating motion in-process, through blood drive blood sample cup 5, influence follow-up detection result, with the problem of connecting, can be various sample cup 5 is opened to the time of the test meter, thereby the convenience and stability of the sample can be improved to the sample analyzer is put forward to the test in order to the test the sample can be more convenient and stable.
In this embodiment, the diameter of blood sample test cup 5 is less than the internal diameter of heat conduction frame 411, the degree of depth of heat conduction frame 411 is less than the degree of depth of blood sample test cup 5, the diameter of blood sample test cup 5 is less than the bottom diameter of seal section of thick bamboo 25, seal section of thick bamboo 25 is fixed in the bottom middle part of vibrations shell fragment lid 20, connecting baffle 405 is when the closure of downstream, can carry out automatic stable sealed closure to heat preservation frame 2 through rubber pad 3, meanwhile, vibrations shell fragment lid 20 can carry out automatic stable sealed closure to blood sample test cup 5 through seal section of thick bamboo 25, and then can effectively avoid external environment temperature to cause harmful effects to the blood sample temperature in the blood sample test cup 5, thereby can guarantee the accuracy of follow-up testing result.
In this embodiment, the internal diameter of locating frame 6 is greater than the diameter of magnet lid 12, the second reset spring 7 cover is established on clamping lever 8, clamping lever 8 symmetric distribution is in the both sides of locating frame 6, clamping lever 8 and haulage rope 9 one-to-one, haulage rope 9 fixes the tip central part at clamping lever 8, haulage rope 9 runs through sliding connection on connecting baffle 405, under the cooperation effect of utilizing clamping lever 8 and draw-in groove 11, the convenient stable dismantlement installation can be carried out to magnet lid 12 to combining locating frame 6, and then can carry out convenient stable dismantlement installation to magnet lid 12, magnet body 13, magnet reflector 14, coil body 15, coil fixing base 16, first shell fragment spacer 17, second shell fragment spacer 18, vibrations shell fragment body 19, vibrations shell fragment lid 20, vibration post 21 and probe 22 constitution's sensing detection head, thereby can carry out convenient stable maintenance or change work to the sensing detection head, guarantee the stability of the long-time operating condition of analysis appearance.
In this embodiment, multi-functional protection subassembly 24 includes fixed pipe 2401, fixed pipe 2401 fixed connection is in unable adjustment base 23, fixed pipe 2401 internal fixation has filter screen board 2402, spacing sliding connection has second rubber piston 2403 in the fixed pipe 2401, fixedly connected with third reset spring 2404 on the second rubber piston 2403, fixed pipe 2401 symmetric distribution is in unable adjustment base 23 inside both sides, filter screen board 2402 symmetric distribution is in the inside both sides of fixed pipe 2401, the side end face of filter screen board 2402 and the side end face parallel and level of unable adjustment base 23, fixedly connected with second cock stem 2405 on the second rubber piston 2403, the other end fixedly connected with guard frame 2406 of second cock stem 2405 runs through sliding connection on filter screen board 2402, fixedly connected with electro-magnet 2407 on guard frame 2406, second cock stem 2405 is fixed in the middle part of second rubber piston 2403, guard frame's inner wall respectively with the outer terminal surface of unable adjustment base 23 and the outer terminal surface laminating of analysis appearance body 1, the side surface of side surface and the outer terminal surface of analysis appearance body are equipped with each other, can carry out the guard frame 2406 simultaneously when the steady operation instrument body 2406 is closed to the side of the electro-magnet 2406, can carry out the steady operation instrument body 2401 simultaneously through the side of the steady operation instrument, can be opened to the guard frame 2406, and the guard frame 2406 can be opened simultaneously, the guard frame 2406 is opened to the side by the steady operation instrument body can be opened by the side of the electro-magnet 2401.
In this embodiment, the bottom of the fixed tube 2401 is connected with a first connecting tube 2408, the bottom of the first connecting tube 2408 is connected with a second connecting tube 2409, the bottom of the second connecting tube 2409 is connected with a rubber suction cup 2410, the second connecting tube 2409 is fixedly connected in the fixed base 23, the fixed tube 2401 is in one-to-one correspondence with the second connecting tube 2409 through the first connecting tube 2408, the first connecting tube 2408 is connected at the middle part of the bottom of the fixed tube 2401, the rubber suction cups 2410 are equidistantly distributed at the bottom of the second connecting tube 2409, the bottom end surface of the rubber suction cup 2410 is smaller than the bottom end surface of the fixed base 23, under the cooperation of the fixed tube 2401 and an internal second rubber piston 2403, internal air of each rubber suction cup 2410 at the bottom of the second connecting tube 2409 can be sucked, at this moment, negative pressure is formed inside each rubber suction cup 2410, and then the whole analyzer body 1 can be automatically and stably adsorbed and fixed on a working table, thereby stability and safety of the subsequent working state of the analyzer body 1 can be ensured, the problem of shaking the analyzer body 1 in the working process is avoided, the touch occurrence of the bottom end surface of the fixed tube 2400 is less than the bottom surface of the fixed tube 2401, the bottom surface of the second connecting tube 2400, the rubber suction tube is fixedly connected with the second connecting tube.
It should be noted that, the present invention is a high-efficiency blood coagulation and platelet function analyzer and its analysis method, firstly, the staff can push the connection baffle 405 downwards, at this moment, under the action of the movement of the connection baffle 405, can drive the ejector rod 407 to move downwards between the fixed rod 408 and the sliding rod 409 through the first plug rod 404, at this moment, during the movement of the ejector rod 407, under the guiding action of the inclined surface at the end of the sliding rod 409 and the inclined surface at the end of the ejector rod 407, the sliding rod 409 can push the ejector rod 407 in the downward movement automatically to move inwards of the first plug rod 404 until the first plug rod 404 drives the ejector rod 407 to move downwards below the sliding rod 409 and separate from the sliding rod 409, at this moment, under the elastic action of the first return spring 406, can drive the ejector rod 407 to automatically move outwards for return, at this moment, the staff can release the connection baffle 405, at this moment, under the elastic action of the powerful spring 402, the connecting baffle 405 on the first plug rod 404 can be pushed to automatically move upwards through the first rubber piston 403, at the moment, under the action of the movement of the first plug rod 404, the first plug rod 404 can be driven to move upwards, at the moment, the first plug rod 404 can push the sliding rod 409 to move upwards through the ejector rod 407 until the sliding rod 409 moves upwards to be attached to the top of the fixed rod 408, at the moment, under the blocking action of the fixed rod 408, the ejector rod 407 in the upward movement process can be pushed to automatically move inwards of the first plug rod 404 again through the inclined surface of the end part of the sliding rod 409, at the same time, until the first plug rod 404 drives the ejector rod 407 to move upwards to be above the fixed rod 408 and separate from the fixed rod 408, at the moment, under the elastic action of the strong spring 402, the connecting baffle 405 on the first plug rod 404 can be pushed to continue to move upwards through the first rubber piston 403, and the heat preservation frame 2 can be opened conveniently, then, a worker can place the blood sample test cup 5 to be used in the heat conduction frame 411, preheat the blood sample test cup 5 by utilizing each electric heating wire 413 in the heat conduction frame 411 to reach 37 ℃ which is similar to the temperature of a human body, and then, the worker can convey the blood sample to be detected and analyzed into the blood sample test cup 5;
Then, a worker can push the connecting baffle 405 downwards again to perform closing operation, at this moment, the connecting baffle 405 can drive the ejector rod 407 on the first plug rod 404 to move downwards to be in contact with the fixed rod 408, at this moment, under the guiding action of the inclined surface at the end part of the fixed rod 408, the ejector rod 407 in the downward movement process can be pushed to move inwards of the first plug rod 404 until the first plug rod 404 drives the ejector rod 407 to move downwards to the lower part of the end part of the fixed rod 408, at this moment, under the elastic action of the first reset spring 406, the ejector rod 407 can be driven to automatically move outwards to reset, then the worker can release the connecting baffle 405, at this moment, under the cooperation of the ejector rod 407 and the fixed rod 408, automatic stable clamping and fixing can be performed, by utilizing the cooperation of the connecting baffle 405 and the rubber pad 3, the heat preservation frame 2 can be automatically closed, at the same time, the connecting baffle 405 can drive the probe 22 to be stably inserted into a blood sample in the blood sample cup 5 when being closed in a downward movement, and the vibration spring plate cover 20 can automatically and stably seal the blood sample cup 5 through the sealing cylinder 25, thereby effectively avoiding bad influence on the blood sample temperature in the blood sample cup 5 caused by environmental temperature;
And when the connecting baffle 405 moves downwards, the first rubber piston 403 at the bottom can be driven to move downwards stably in the fixed sleeve 401 through the first plug rod 404, so that air in the fixed sleeve 401 can be conveyed into the rubber air bag 412 through the air duct 410, the rubber air bag 412 can be automatically inflated, and further the blood sample test cup 5 can be conveniently and stably extruded and fixed, so that the problem that the follow-up detection result is influenced due to the fact that the blood drives the blood sample test cup 5 to shake in the reciprocating motion process of the probe 22 can be effectively avoided, and similarly, when the connecting baffle 405 moves upwards and is opened, the first rubber piston 403 moves and resets, the rubber air bag 412 is restored to be original, and further the follow-up taking and placing work of the blood sample test cup 5 can be ensured to be stable and convenient;
after the probe 22 is stably inserted into the blood sample in the blood sample test cup 5, a sinusoidal signal of about 200Hz is output by the analyzer body 1, an alternating magnetic field is generated when current passes through the coil body 15, the magnetic field changes along with the change of the current, and as the coil body 15 is positioned in a constant magnetic field generated by the magnet body 13, interaction force exists between the magnetic field generated by the current and the magnetic field generated by the magnet body 13, and the interaction force also changes because of the change of the electromagnetic field; the coil body 15 is fixed on an elastic structure formed by two vibrating spring plate bodies 19, and the coil is pushed/pulled to move simultaneously due to the change of magnetic force, the elastic structure is subjected to the action of magnetic force and elastic force to reciprocate, a vibrating column 21 is fixed on the elastic structure, and the probe 22 can be driven to contact with blood of a tested substance and reciprocate under the driving of the vibrating column 21; when the probe 22 reciprocates in the tested substance, the vibration characteristic of the probe 22 will change due to the action of the blood viscosity force, through the change quantity, the vibration frequency change quantity of the sensor can be converted into the viscosity change quantity, in the blood coagulation process, the sensor senses the blood viscosity change, the change of the voltage can be converted into the change of the blood coagulation signal through the definition, the electric signal is converted into a digital signal, and the digital signal is depicted on the display screen of the analyzer body 1, so that the analysis work of the blood coagulation and blood platelet functions is completed;
Before the analyzer body 1 starts to perform detection and analysis, a worker needs to place the analyzer body 1 on a workbench surface and close an electromagnet 2407 on a protective frame 2406, at this time, under the elastic action of a third reset spring 2404, the protective frames 2406 on two sides can be pushed to move sideways simultaneously through a second plug rod 2405, at this time, the protective frames 2406 on two sides are opened in a moving way, then the worker can operate and use the analyzer body 1, at the same time, in the moving process of the second plug rod 2405 to the sideways, the second rubber piston 2403 can suck the internal air of each rubber sucker 2410 on the bottom of the second connecting pipe 2409 through a first connecting pipe 2408, at this time, each rubber sucker 2410 can form negative pressure, and then the whole automatic stable adsorption of the analyzer body 1 can be fixed on the workbench surface through a fixed base 23, so that the stability and safety of the subsequent working state of the analyzer body 1 can be ensured, the problem that blood samples in the blood sample cup 5 are inclined and scattered can be solved, and when the analyzer body 2401 is finished, the electromagnet 2406 can be pushed to move to the inner side of the protective frame 2406, and the analyzer body 2406 can be opened, and the air pressure can be restored to the normal state when the analyzer body 2401 is closed through the second plug rod 2406;
And after the long-time work of analyzer body 1, staff's accessible drive connection baffle 405 upwards moves and opens, then staff's accessible upwards pulls go up go-between 10, go-between 10 can simultaneously pull the clamping lever 8 of locating frame 6 both sides to the avris motion through haulage rope 9 of both sides, until clamping lever 8 motion breaks away from draw-in groove 11 on the magnet lid 12, then can be to magnet lid 12, magnet body 13, magnet reflector plate 14, coil body 15, coil fixing base 16, first shell fragment spacer 17, second shell fragment spacer 18, vibrations shell fragment body 19, vibrations shell fragment lid 20, the sensing detection head that vibration post 21 and probe 22 constitute carries out convenient stable dismantlement installation, thereby can carry out convenient stable maintenance or change work to the sensing detection head, and when the sensing detection head carries out the block installation, only need keep clamping lever 8 to the motion state of avris, and insert magnet lid 12 into locating frame 6, then the staff only need unclamp go-between 10, under the elastic action of second reset spring 7, can drive clamping lever 8 and rotate to the sensing detection head 11 that the clamping lever 12 carries out convenient stable dismantlement installation, thereby can carry out steady state to the steady state of work after the sensing detection head, and the steady state can be guaranteed to the steady state of work and stable to the sensing detection head.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the invention.
Claims (6)
1. The utility model provides an efficient blood coagulation and platelet function analysis appearance, its characterized in that, including analysis appearance body (1) and locating frame (6), the top fixedly connected with heat preservation frame (2) of analysis appearance body (1), the top fixedly connected with rubber pad (3) of heat preservation frame (2), install high-efficient detection subassembly (4) in heat preservation frame (2), be provided with blood sample test cup (5) in high-efficient detection subassembly (4), the side fixedly connected with second reset spring (7) of locating frame (6), the other end fixedly connected with kelly (8) of second reset spring (7), kelly (8) run through sliding connection be in the side of locating frame (6), the one end fixedly connected with haulage rope (9) of kelly (9), the other end fixedly connected with go-between (10) of kelly (8), the other end block connection of kelly (11) is in draw-in groove (11), draw-in groove (11) are seted up in magnet lid (12), magnet lid (16) are provided with magnet body (13) bottom (16), magnet (16) are provided with fixing base (13) in the magnet body, magnet (16), the device comprises a coil fixing seat (16), a first elastic sheet isolation column (17) is fixedly connected to the bottom of the coil fixing seat (16), a second elastic sheet isolation column (18) is arranged in the first elastic sheet isolation column (17), a vibration elastic sheet body (19) is connected to the second elastic sheet isolation column (18), a vibration elastic sheet cover (20) is fixedly connected to the bottom of the first elastic sheet isolation column (17), a vibration column (21) is fixedly arranged at the bottom of the vibration elastic sheet cover (20), a probe (22) is arranged in the vibration column (21), a fixing base (23) is fixedly connected to the bottom end of the analyzer body (1), a multifunctional protection assembly (24) is arranged in the fixing base (23), and a sealing cylinder (25) is fixedly connected to the bottom end face of the vibration elastic sheet cover (20);
The high-efficiency detection assembly (4) comprises a fixed sleeve (401), wherein the bottom end of the fixed sleeve (401) is fixedly connected to the inner bottom end face of the heat preservation frame (2), a strong spring (402) is fixedly connected to the inner bottom end face of the fixed sleeve (401), a first rubber piston (403) is fixedly connected to the top end of the strong spring (402), the first rubber piston (403) is in limit sliding connection in the fixed sleeve (401), a first plug rod (404) is fixedly connected to the top end of the first rubber piston (403), a connecting baffle plate (405) is fixedly connected to the top end of the first plug rod (404), the central axis of the fixed sleeve (401) and the central axis of the heat preservation frame (2) are located on the same vertical central line, the top end face of the heat preservation frame (2) is flush with the top end face of the fixed sleeve (401), the cross section of the fixed sleeve (401) is rectangular, the inner wall of the fixed sleeve (401) is attached to the side end face of the first rubber piston (403), the first plug rod (404) is fixedly connected to the connecting baffle plate (405), and the central axis of the first plug rod (404) is located on the same vertical central line, and the length of the heat preservation frame (405) is larger than the length of the heat preservation frame (2);
The novel plug is characterized in that a first reset spring (406) is fixedly connected in the first plug rod (404), the other end of the first reset spring (406) is fixedly connected with a push rod (407), the push rod (407) is in limiting sliding connection in the first plug rod (404), a fixed rod (408) is fixedly connected in the fixed sleeve (401), a sliding rod (409) is in limiting sliding connection on the fixed rod (408), the first reset springs (406) are symmetrically distributed on two sides of the first plug rod (404), the first reset springs (406) are in one-to-one correspondence with the push rod (407), the cross section of the end part of the push rod (407) is in a right triangle shape, the end part of the fixed rod (408) is in an inclined shape, and the cross section of the end part of the sliding rod (409) is in an isosceles triangle shape;
the air guide device is characterized in that an air guide pipe (410) is connected to the bottom side end of the fixing sleeve (401), a rubber air bag (412) is connected to the other end of the air guide pipe (410), the rubber air bag (412) is fixedly connected to the inside of the heat conducting frame (411), an electric heating wire (413) is arranged in the heat conducting frame (411), the bottom end of the heat conducting frame (411) is fixedly connected to the inner bottom end face of the heat insulating frame (2), the bottom end of the connecting baffle (405) is fixedly connected to the top end of the positioning frame (6), the bottom end face of the connecting baffle (405) is attached to the top end face of the magnet cover (12), the air guide pipes (410) are symmetrically distributed on two sides of the bottom of the fixing sleeve (401), the air guide pipes (410) are in one-to-one correspondence with the heat conducting frame (411) through the rubber air bags (412), the rubber air bags (412) and the heat conducting frame (411) are cylindrical, and the electric heating wires (413) are equidistantly distributed in the heat conducting frame (411).
The diameter of the blood sample test cup (5) is smaller than the inner diameter of the heat conduction frame (411), the depth of the heat conduction frame (411) is smaller than the depth of the blood sample test cup (5), the diameter of the blood sample test cup (5) is smaller than the bottom diameter of the sealing cylinder (25), and the sealing cylinder (25) is fixed at the middle part of the bottom of the vibration elastic sheet cover (20).
2. A high efficiency coagulation and platelet function analyzer as set forth in claim 1, wherein: the inner diameter of the positioning frame (6) is larger than the diameter of the magnet cover (12), the second reset spring (7) is sleeved on the clamping rods (8), the clamping rods (8) are symmetrically distributed on two sides of the positioning frame (6), the clamping rods (8) are in one-to-one correspondence with the traction ropes (9), the traction ropes (9) are fixed on the center parts of the end parts of the clamping rods (8), and the traction ropes (9) penetrate through the connecting baffle plates (405) in a sliding mode.
3. A high efficiency coagulation and platelet function analyzer as set forth in claim 1, wherein: the multifunctional protection assembly (24) comprises a fixed pipe (2401), the fixed pipe (2401) is fixedly connected in the fixed base (23), a filter screen plate (2402) is fixedly connected in the fixed pipe (2401), a second rubber piston (2403) is fixedly connected in the fixed pipe (2401) in a limiting sliding manner, a third reset spring (2404) is fixedly connected on the second rubber piston (2403), the fixed pipe (2401) is symmetrically distributed on two sides inside the fixed base (23), the filter screen plate (2402) is symmetrically distributed on two sides inside the fixed pipe (2401), and the side end face of the fixed pipe (2401), the side end face of the filter screen plate (2402) and the side end face of the fixed base (23) are flush.
4. A high efficiency coagulation and platelet function analyzer as claimed in claim 3, wherein: the device is characterized in that a second plug rod (2405) is fixedly connected to the second rubber piston (2403), a protection frame (2406) is fixedly connected to the other end of the second plug rod (2405), the second plug rod (2405) penetrates through and is slidably connected to the filter screen plate (2402), an electromagnet (2407) is fixedly connected to the protection frame (2406), the second plug rod (2405) is fixed to the middle part of the second rubber piston (2403), and the inner wall of the protection frame (2406) is respectively attached to the outer end face of the fixed base (23) and the outer end face of the analyzer body (1).
5. A high efficiency coagulation and platelet function analyzer as claimed in claim 3, wherein: the bottom of fixed pipe (2401) is connected with first connecting pipe (2408), the bottom of first connecting pipe (2408) is connected with second connecting pipe (2409), the bottom of second connecting pipe (2409) is connected with rubber sucking disc (2410), second connecting pipe (2409) fixed connection is in unable adjustment base (23), fixed pipe (2401) are through first connecting pipe (2408) with second connecting pipe (2409) one-to-one, first connecting pipe (2408) are connected in the bottom middle part of fixed pipe (2401), rubber sucking disc (2410) equidistance distributes the bottom of second connecting pipe (2409), the height of rubber sucking disc (2410) bottom face is less than the height of unable adjustment base (23) bottom face.
6. A method for efficient coagulation and platelet function analysis using the efficient coagulation and platelet function analyzer of claim 1, comprising the steps of:
s1: the analyzer body (1) is placed on the workbench surface, and the multifunctional protection assembly (24) is started, so that the multifunctional protection assembly (24) can automatically adsorb and fix the analyzer body (1) on the workbench surface;
s2: the blood sample test cup (5) is placed in the high-efficiency detection assembly (4) for preheating, and after the blood sample test cup is preheated to 37 degrees, the blood sample can be conveyed into the blood sample test cup (5);
s3: the high-efficiency detection assembly (4) is driven to automatically position and fix the blood sample test cup (5), and the probe (22) can be inserted into the central part inside the blood sample test cup (5);
s4: the coil body (15) is positioned in a constant magnetic field generated by the magnet body (13), and interaction force exists between the magnetic field generated by the current and the magnetic field generated by the magnet body (13); the coil body (15) is fixed on an elastic structure formed by two vibrating spring plate bodies (19), and the coil is pushed/pulled to move simultaneously due to the change of magnetic force, the elastic structure is subjected to the action of the magnetic force and the elastic force to reciprocate, and a vibrating column (21) is fixed on the elastic structure, so that a probe (22) can be driven to contact blood and reciprocate under the driving of the vibrating column (21); when the probe (22) reciprocates in the tested substance, the sensor senses the change of blood viscosity in the blood coagulation process, the change of voltage is converted into the change of blood coagulation signals, the electric signals are converted into digital signals, and the digital signals are depicted on a display screen of the analyzer body (1) to finish the detection and analysis work of blood coagulation and platelet functions.
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| CN217980374U (en) * | 2022-09-15 | 2022-12-06 | 苏州星格纳测控技术有限公司 | Sensor waterproof construction |
| CN219201619U (en) * | 2022-12-30 | 2023-06-16 | 宝锐生物科技泰州有限公司 | Tubular probe of coagulation analyzer and coagulation analyzer |
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| CN116577490A (en) | 2023-08-11 |
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