CN116549779A - Drug delivery device and drug delivery method - Google Patents

Drug delivery device and drug delivery method Download PDF

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Publication number
CN116549779A
CN116549779A CN202210113449.3A CN202210113449A CN116549779A CN 116549779 A CN116549779 A CN 116549779A CN 202210113449 A CN202210113449 A CN 202210113449A CN 116549779 A CN116549779 A CN 116549779A
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CN
China
Prior art keywords
push rod
channel
barrel
medicine
stopper
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210113449.3A
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Chinese (zh)
Inventor
王岳柏
刘鹏
王忠义
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhejiang Jiaoyang Biomedical Technology Co ltd
Original Assignee
Zhejiang Jiaoyang Biomedical Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhejiang Jiaoyang Biomedical Technology Co ltd filed Critical Zhejiang Jiaoyang Biomedical Technology Co ltd
Priority to CN202210113449.3A priority Critical patent/CN116549779A/en
Publication of CN116549779A publication Critical patent/CN116549779A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02WCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W90/00Enabling technologies or technologies with a potential or indirect contribution to greenhouse gas [GHG] emissions mitigation
    • Y02W90/10Bio-packaging, e.g. packing containers made from renewable resources or bio-plastics

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  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention relates to a drug dispenser and a drug delivery method, wherein the drug dispenser comprises a barrel (10) and a push rod (20), the barrel (10) is provided with a containing cavity for storing a drug, the barrel (10) is provided with a first limit part (15), the push rod (20) is slidably connected to the inner surface of the containing cavity, the push rod (20) is provided with a first channel (211) and a second channel (212), the first limit part (15) is configured to move in the first channel (211) when the push rod (20) pushes the drug out of the barrel (10), and move in the second channel (212) when the push rod (20) is pulled outwards to enable the drug to enter the barrel (10). According to the embodiment of the invention, the first channel and the second channel are arranged at the same time, so that the bidirectional movement paths of the push rod are mutually independent, the mutual influence is avoided, the movement paths of the push rod are simplified, and the movement efficiency of the push rod is improved.

Description

Drug delivery device and drug delivery method
Technical Field
The invention relates to the technical field of drug delivery, in particular to a drug delivery device and a drug delivery method.
Background
The syringe is an appliance widely used in the fields of medical treatment and the like, and the principle is that after liquid is sucked into a container cavity, a push rod is pushed to discharge medicament during injection. The outer wall of the injection tube of the conventional injector is provided with a measuring ruler, medical staff determines the injection amount of each time according to the measuring ruler, and then presses a pushing handle on the pushing rod to push the piston to move, so that the liquid medicine in the injection tube enters the target object through the needle head.
However, in some special situations, it may be necessary to inject the medicament into a certain part of the target with great precision, for example, in the course of treating some diseases of the nasal cavity or oral cavity, it is often necessary to dose some liquid medicament to the nostril or oral cavity. There are other diseases in which it is also necessary to quantitatively spray the corresponding medicine in the nasal cavity or oral cavity so as to facilitate the inhalation of the medicine into the body from the nasal cavity or oral cavity.
However, the accuracy of conventional syringes is generally difficult to meet injection requirements. In emergency situations or in complex environments, it is difficult to precisely control the quantitative administration of the syringe, which brings great inconvenience to medical workers. On the other hand, after the self-destruction injector in the current market finishes injection, the operation of destroying again still needs to be manually performed, so that the workload of operators is increased, and the complete self-destruction operation is difficult to ensure under some emergency conditions. In addition, the conventional syringe has a relatively complex movement path of the push rod during medicament extraction and lower extraction efficiency.
It should be noted that the information disclosed in the background section of the present invention is only for increasing the understanding of the general background of the present invention and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person skilled in the art.
Disclosure of Invention
The embodiment of the invention provides a drug feeder and a drug feeding method, which are beneficial to improving the movement efficiency of a push rod.
According to one aspect of the present invention there is provided an applicator comprising:
the barrel is provided with a containing cavity for storing medicines, and a first limiting part is arranged on the barrel; and
the push rod is slidably engaged with the inner surface of the accommodating cavity, the push rod is provided with a first channel and a second channel, and the first limiting part is configured to move in the first channel when the push rod pushes the medicine out of the barrel body and move in the second channel when the push rod is pulled outwards to enable the medicine to enter the barrel body.
In some embodiments, the first channel extends along an axial direction of the pushrod and has a bend.
In some embodiments, the second channel is parallel to the axial direction of the pushrod.
In some embodiments, the drug delivery device further comprises a second stop portion disposed on the barrel and a third stop portion disposed on the pushrod, the second stop portion and the third stop portion being configured to cooperate to prevent movement of the pushrod in a direction of drug entering the barrel after all of the drug is expelled from the barrel.
In some embodiments, the second limiting portion includes a plurality of limiting pieces, a first end of the plurality of limiting pieces is connected with the barrel, the plurality of limiting pieces are arranged at intervals along a circumferential direction of the barrel and a second end of the plurality of limiting pieces is inclined in a direction close to an axis of the barrel, an outer diameter of the third limiting portion gradually increases along a direction in which medicine enters the barrel, a blocking surface is arranged on one side, far away from the medicine inlet and outlet of the barrel, of the third limiting portion, and the plurality of limiting pieces are opened when the third limiting portion passes through the second limiting portion and are contracted to abut against the blocking surface after the third limiting portion passes through the second limiting portion.
In some embodiments, a first distance between a trailing end of the first channel proximate the apply end of the pushrod and the apply end of the pushrod is greater than a second distance between a trailing end of the second channel proximate the apply end of the pushrod and the apply end of the pushrod.
In some embodiments, the applicator further comprises an anti-disengagement structure configured to prevent the pushrod from exiting the receiving cavity.
In some embodiments, the anti-drop structure includes a fourth limiting portion disposed in the receiving cavity and a first boss disposed in the push rod, an outer diameter of the first boss being greater than an inner diameter of the fourth limiting portion.
In some embodiments, the drug delivery device further comprises a piston, the receiving chamber comprises a first chamber for storing the drug, the piston is mounted to the push rod, and the piston comprises a portion having an outer diameter substantially equal to an inner diameter of the first chamber.
In some embodiments, the push rod is provided with a second boss against which the piston and the second boss bear against each other in the axial direction of the cylinder.
According to another aspect of the present invention, there is provided a method of administering a drug based on the above-described drug dispenser, comprising:
the push rod rotates relative to the cylinder body so that the first limiting part enters the second channel;
under the guiding action of the second channel, the push rod is pulled in the direction away from the medicine inlet and outlet of the cylinder body, so that the medicine enters the accommodating cavity;
the push rod rotates relative to the cylinder body so that the first limiting part enters the first channel; and
under the guiding action of the first channel, the push rod is pushed to the direction close to the medicine inlet and outlet of the cylinder body so as to push the medicine out of the cylinder body.
Based on the technical scheme, in the embodiment of the invention, the first channel and the second channel are simultaneously arranged on the push rod, when the medicine is pushed out of the cylinder body, the first limiting part can move in the first channel, and the push rod moves relative to the cylinder body under the guiding effect formed by the mutual matching of the first limiting part and the first channel; when the medicine enters the cylinder, the first limiting part can move in the second channel, and the push rod moves relative to the cylinder under the guiding action formed by the mutual matching of the first limiting part and the second channel, so that the push rod moves under the guiding of different channels respectively when the medicine is pushed out of the cylinder and the medicine enters the cylinder, the influence of the movement path of the push rod when the medicine is pushed out of the cylinder on the movement path of the push rod when the medicine enters the cylinder is avoided, the movement path of the push rod when the medicine is pushed out of the cylinder is simplified, and the movement efficiency of the push rod is improved.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiments of the invention and together with the description serve to explain the invention and do not constitute a limitation on the invention. In the drawings:
fig. 1 is a schematic view of the structure of some embodiments of the applicator of the present invention.
Fig. 2 is a front view of a cartridge in some embodiments of the applicator of the present invention.
Fig. 3 is a cross-sectional view of a cartridge in some embodiments of the applicator of the present invention.
Fig. 4 is a front view of a push rod in some embodiments of the applicator of the present invention.
Fig. 5 is a cross-sectional view of a push rod in some embodiments of the applicator of the present invention.
Fig. 6 is a schematic view of the structure of a piston in some embodiments of the applicator of the present invention.
Fig. 7 is a schematic view of the structure of some embodiments of the applicator of the present invention in a first state.
Fig. 8 is a cross-sectional view of some embodiments of the applicator of the present invention in a first state.
Fig. 9 is a schematic view of some embodiments of the applicator of the present invention in a second state.
Fig. 10 is a cross-sectional view of some embodiments of the applicator of the present invention in a second state.
Fig. 11 is a cross-sectional view of a portion of the structure of some embodiments of the applicator of the present invention in a second state.
In the figure:
10. a cylinder; 11. a first chamber; 12. a second chamber; 13. a handle; 14. a connector; 15. a first limit part; 16. a second limit part; 17. a fourth limit part; 18. a drug inlet and outlet; 19. a push rod inlet and outlet;
20. a push rod; 21. a first push rod part; 211. a first channel; 212. a second channel; 213. a cavity; 22. a second push rod portion; 23. a third push rod portion; 231. a third limit part; 232. a first boss; 233. a second boss; 234. a groove; 24. a push handle; 241. an anti-slip strip;
30. and (3) a piston.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments. It will be apparent that the described embodiments are only some, but not all, embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the description of the present invention, it should be understood that the terms "center," "lateral," "longitudinal," "front," "rear," "left," "right," "upper," "lower," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate orientations or positional relationships based on the orientation or positional relationships shown in the drawings, merely to facilitate describing the present invention and simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the scope of the present invention.
Referring to fig. 3 and 7, in some embodiments of the present invention, the dispenser includes a barrel 10 and a push rod 20, the barrel 10 is provided with a receiving cavity for storing a medicine, the barrel 10 is provided with a first stopper 15, the push rod 20 is slidably engaged with an inner surface of the receiving cavity, and the push rod 20 is provided with a first channel 211 and a second channel 212, the first stopper 15 is configured to move in the first channel 211 when the push rod 20 pushes the medicine out of the barrel 10 and to move in the second channel 212 when the push rod 20 is pulled out to allow the medicine to enter the barrel 10.
In the above embodiment, the push rod 20 is provided with the first channel 211 and the second channel 212 at the same time, when the medicine is pushed out of the barrel 10, the first limiting part 15 can move in the first channel 211, and the push rod 20 moves relative to the barrel 10 under the guiding action formed by the mutual matching of the first limiting part 15 and the first channel 211; when the medicine is introduced into the barrel 10, the first limiting part 15 can move in the second channel 212, and the push rod 20 moves relative to the barrel 10 under the guiding action formed by the mutual matching of the first limiting part 15 and the second channel 212, so that the push rod 20 moves under the guiding action of different channels when the medicine is pushed out of the barrel 10 and the medicine is introduced into the barrel 10, the influence of the movement path of the push rod 20 when the medicine is pushed out of the barrel 10 on the movement path of the push rod 20 when the medicine is introduced into the barrel 10 is avoided, for example, when a channel for guiding the movement of the push rod is arranged to be complex for realizing quantitative medicine or continuous multiple times of medicine administration, the movement efficiency of the push rod is reduced when the medicine is introduced into the barrel 10 if the channel is still used, and the medicine extraction efficiency is further reduced. Therefore, by providing two channels, the embodiment of the present invention is beneficial to simplifying the movement path of the push rod 20 when the medicine enters the barrel 10 and improving the movement efficiency of the push rod 20.
In some embodiments, the first limiting portion 15 is disposed on an inner wall of the accommodating chamber of the barrel 10. Therefore, the push rod 20 can be limited in the accommodating cavity of the cylinder 10 through the first limiting part 15, and compared with the scheme of limiting the push rod 20 at the end part or the outside of the cylinder 10, the push rod 20 is beneficial to ensuring the stability of the movement of the push rod 20.
Referring to fig. 3, the first stopper 15 includes a projection provided on the inner wall of the accommodating chamber of the cylinder 10. In the circumferential direction of the cylinder 10, a plurality of first stopper portions 15 may be provided at intervals, while a plurality of first passages 211 and a plurality of second passages 212 may be provided on the push rod 20 at intervals, respectively.
By providing the plurality of first stopper portions 15 in the circumferential direction, the insertion of the push rod 20 can be guided, and the push rod 20 can be prevented from rotating relative to the cylinder 10 during the insertion.
In some embodiments, the push rod 20 is configured to be rotatable relative to the barrel 10 to effect switching of the first limiter 15 between the first channel 211 and the second channel 212.
In some embodiments, the first channel 211 includes a first groove provided on the push rod 20 such that the first stop 15 is embedded in the first groove and moves along an extension path of the first groove during movement of the push rod 20 relative to the barrel 10, thereby guiding movement of the push rod 20 relative to the barrel 10 along the extension path of the first groove.
In some embodiments, the second channel 212 includes a second groove provided on the push rod 20 such that the first stop 15 is embedded in the second groove and moves along the extension path of the second groove during movement of the push rod 20 relative to the barrel 10, thereby guiding movement of the push rod 20 relative to the barrel 10 along the extension path of the second groove.
In some embodiments, the first channel 211 extends along the axial direction of the pushrod 20 and has a bend. By providing the bending, the first stopper 15 can be stopped at the bending position, and a prompt signal about the dosage can be given to the operator. The first limiting portion 15 is embedded in the first channel 211 and can prevent the push rod 20 from rotating relative to the cylinder 10 during the process of moving along the first channel 211.
The bending device is arranged at a preset position, so that quantitative drug administration can be realized. The relationship between the amount of administered and the length of movement of the push rod 20 in the axial direction is: dosing v=cross-sectional area S of the cylinder 10×movement length L of the push rod 20 in the axial direction.
In some embodiments, the first channel 211 extends along the axial direction of the pushrod 20 and has a plurality of bends. By providing a plurality of bends, a continuous multiple dosing can be achieved.
In the embodiment shown in fig. 4, the first channel 211 includes a bend, and has a predetermined length before and after the bend, so that two dosing operations can be performed.
In some embodiments, the second channel 212 is parallel to the axial direction of the pushrod 20. The arrangement can make the path of the second channel 212 simpler, and can make the push rod 20 move along the axial direction of the push rod when the medicine enters the barrel 10, without turning, reduce the bending, effectively improve the movement efficiency of the push rod 20 and improve the medicine extraction efficiency.
In some embodiments, the width of the first channel 211 and the second channel 212 is slightly greater than the width of the first stop 15, such that the first stop 15 is free to slide within the first channel 211 and the second channel 212.
In some embodiments, the length of the first channel 211 is configured to satisfy a preset amount of medicament to bring the total amount of medicament extracted to the preset amount of medicament when the medicament is extracted and the first limiter 15 reaches the end of the first channel 211 distal from the force application end of the push rod 20.
In some embodiments, the dispenser further comprises a second stop 16 provided to the barrel 10 and a third stop 231 provided to the push rod 20, the second stop 16 and the third stop 231 being configured to cooperate to prevent movement of the push rod 20 in the direction of the drug entering the barrel 10 after the drug has been pushed entirely out of the barrel 10.
Through setting up second spacing portion 16 and third spacing portion 231, can make second spacing portion 16 and third spacing portion 231 mutually support after all being pushed out barrel 10 with the medicine to prevent push rod 20 along the direction motion of medicine entering barrel 10, realize the self-destruction function of ware promptly, prevent that used ware of dosing from being used by the secondary and cause disease cross infection scheduling problem.
As shown in fig. 3, in some embodiments, the second stopper 16 includes a plurality of stopper pieces, first ends of which are connected with the cylinder 10, the plurality of stopper pieces being arranged at intervals along the circumference of the cylinder 10 and second ends of which are inclined in a direction approaching the axis of the cylinder 10. This allows the second stopper 16 to be formed in a necked-down structure, and the second ends of the stopper pieces can be outwardly opened with respect to the axis of the cylinder 10 due to the gaps between the adjacent two stopper pieces in the circumferential direction.
As shown in fig. 4 and 5, the outer diameter of the third limit part 231 is gradually increased in the direction in which the medicine enters the cylinder 10, and one side of the third limit part 231, which is far from the medicine inlet and outlet 18 of the cylinder 10, has a blocking surface, and the plurality of limit pieces are opened when the third limit part 231 passes through the second limit part 16, and are contracted to abut against the blocking surface after the third limit part 231 passes through the second limit part 16.
After the push rod 20 is installed in the cylinder 10 and the liquid medicine in the accommodating cavity of the cylinder 10 is pushed out by pushing the push rod 20, the push rod 20 can be pushed to move continuously along with further force applied to the push rod 20. In the process of continuing movement of the push rod 20, the third limiting part 231 can outwards jack the limiting piece, so that the third limiting part 231 can penetrate through the second limiting part 16, the abutting action of the third limiting part 231 on the limiting piece disappears after the third limiting part 231 penetrates through the second limiting part 16, the limiting piece can automatically reset and restore to the necking structure, the blocking surface can be contacted with the second end of the limiting piece, the third limiting part 231 is prevented from reversely penetrating through the second limiting part 16, the purpose of preventing the push rod 20 from moving along the direction of the medicine entering the barrel 10 is achieved, and the used medicine feeder is prevented from being reused.
In some embodiments, the first channel 211 and the second channel 212 have a communication port therebetween, and the first limiting portion 15 switches between the first channel 211 and the second channel 212 through the communication port. The first channel 211 and the second channel 212 each extend substantially along the axial direction of the push rod 20, and the communication port extends along the circumferential direction of the push rod 20 to realize switching of the first stopper 15 between the first channel 211 and the second channel 212 by rotating the push rod 20.
As shown in fig. 4, in some embodiments, a first distance d1 between a trailing end of the first channel 211 near the force-applying end of the push rod 20 and the force-applying end of the push rod 20 is greater than a second distance d2 between a trailing end of the second channel 212 near the force-applying end of the push rod 20 and the force-applying end of the push rod 20. The advantage of this arrangement is that when the first limit part 15 moves to the tail end of the first channel 211, it is ensured that the second limit part 16 does not reach a position where the third limit part 231 can be penetrated, and the applicator is prevented from being self-destroyed in advance; meanwhile, the second distance d2 is smaller than the first distance d1, so that the push rod 20 can further move continuously after the medicine is pushed out of the cylinder 10, the self-destruction purpose is achieved, and the realization of the self-destruction function is effectively ensured.
In some embodiments, the applicator further comprises an anti-disengagement structure configured to prevent the push rod 20 from exiting the receiving cavity. By providing an anti-drop feature, the push rod 20 can be prevented from leaving the receiving cavity, for example, when the push rod 20 is pulled outwardly to extract a drug, the push rod 20 can be prevented from being pulled past a defined position by a user to affect the accuracy of the amount of drug extracted.
In some embodiments, the anti-disengaging structure includes a fourth limiting portion 17 disposed in the receiving cavity and a first boss 232 disposed in the push rod 20, an outer diameter of the first boss 232 being greater than an inner diameter of the fourth limiting portion 17.
The fourth limiting part 17 may be an annular protrusion provided at an inner wall of the receiving chamber, and by the annular protrusion and the outer diameter of the first boss 232, the first boss 232 may be prevented from reversely passing through the fourth limiting part 17 after the push rod 20 moves to a position where the first boss 232 passes through the fourth limiting part 17, thereby preventing the push rod 20 from leaving the cylinder 10.
The fourth limiting part 17 contacts with the first boss 232, and can be used as a mark for achieving the requirement of the medicine extraction amount, so as to realize quantitative extraction.
In some embodiments, the fourth stopper 17 may be provided in a tapered structure, and the inner diameter of the fourth stopper 17 gradually decreases in a direction approaching the medicine port 18 of the cartridge 10. During the process of pushing the push rod 20, the first boss 232 can gradually pass through the fourth limiting part 17 under the action of pushing force, and after the first boss 232 passes through the fourth limiting part 17, the inner diameter of the fourth limiting part 17 gradually increases in the direction away from the medicine inlet and outlet 18 of the barrel 10 and can be subjected to larger resistance of reverse movement, so that the effect of preventing the push rod 20 from moving reversely can be realized, and the push rod 20 is prevented from leaving the barrel 10.
As shown in fig. 6, in some embodiments, the dispenser further comprises a piston 30, the receiving chamber comprises a first chamber 11 for storing the medicament, the piston 30 is mounted to the push rod 20, and the piston 30 comprises a portion having an outer diameter substantially equal to an inner diameter of the first chamber 11.
By providing the piston 30 with a portion of the piston 30 having an outer diameter substantially equal to the inner diameter of the first chamber 11, the adhered medicine in the chamber wall of the first chamber 11 can be scraped off by the piston 30 when the medicine is pushed out of the cylinder 10, which is advantageous in achieving the purpose of discharging the whole medicine.
As shown in fig. 4 and 5, in some embodiments, the push rod 20 is provided with a second boss 233, and the piston 30 and the second boss 233 are abutted against each other in the axial direction of the cylinder 10.
By providing the second boss 233, movement of the piston 30 relative to the push rod 20 in a direction away from the drug access port 18 of the cartridge 10 can be prevented, avoiding losing the effect of scraping off the drug adhered in the cavity wall of the first cavity 11 due to axial movement of the piston 30 relative to the push rod 20.
The first boss 232 and the second boss 233 may be integrally formed; alternatively, the first boss 232 and the second boss 233 are spaced apart.
The outer diameters of the first boss 232 and the second boss 233 may be the same or different. The outer diameter of the first boss 232 needs to be larger than the minimum inner diameter of the fourth limiting portion 17. The outer diameter of the second boss 233 is desirably greater than the inner bore diameter of the piston 30.
The piston 30 is provided with an inner hole, and the piston 30 is sleeved on the periphery of the push rod 20 through the inner hole.
The piston 30 may be made of rubber plugs or other elastic materials.
The invention also provides a drug delivery method based on the drug delivery device, which comprises the following steps:
rotating the push rod 20 relative to the cylinder 10 so that the first limiting part 15 enters the second channel 212;
under the guiding action of the second channel 212, the push rod 20 is pulled in a direction away from the medicine inlet and outlet 18 of the barrel 10, so that medicine enters the accommodating cavity;
rotating the push rod 20 relative to the cylinder 10 so that the first limiting part 15 enters the first channel 211; and
the push rod 20 is pushed in a direction approaching the medicine inlet 18 of the cartridge 10 by the guide of the first passage 211 to push the medicine out of the cartridge 10.
The structure and operation of one embodiment of the applicator of the present invention will now be described with reference to figures 1 to 11:
as shown in fig. 1, the applicator includes a barrel 10 and a push rod 20. The cylinder 10 is provided with a receiving chamber inside, into which the push rod 20 is partially inserted.
As shown in fig. 2 and 3, the receiving chamber inside the cartridge 10 includes a first chamber 11 and a second chamber 12, the first chamber 11 for storing a medicine. The inner diameter of the second chamber 12 is larger than the inner diameter of the first chamber 11.
The end of the barrel 10 adjacent the second chamber 12 is provided with a handle 13, the handle 13 extending from the edge of the second chamber 12 in a direction away from the axis of the barrel 10. The end of the barrel 10 adjacent to the first chamber 11 is provided with a connector 14, the connector 14 being for connection to an injection needle.
The end of the connector 14 remote from the first chamber 11 defines a drug access port 18 through which drug enters the cartridge 10 or from which drug exits the cartridge 10 through the drug access port 18. The through hole provided in the center of the handle 13 and communicating with the second chamber 12 forms a push rod inlet/outlet 19, through which push rod inlet/outlet 19 the push rod 20 can be fitted into the cartridge 10 and, if necessary, can leave the cartridge 10 through the push rod inlet/outlet 19.
First limiting portions 15 are provided inside the second chamber 12 at positions close to the handle 13, and the two first limiting portions 15 are arranged symmetrically at intervals in the circumferential direction of the cylinder 10.
A second limiting part 16 is arranged at the transition position of the first cavity 11 and the connector 14. The second stopper 16 includes a plurality of stopper pieces, first ends of which are connected with the cylinder 10, which are arranged at intervals along the circumference of the cylinder 10 and second ends of which are inclined in a direction approaching the axis of the cylinder 10.
A fourth limiting part 17 is arranged at the transition position of the first cavity 11 and the second cavity 12, and the inner diameter of the fourth limiting part 17 gradually decreases in the direction of approaching the medicine inlet and outlet 18 of the barrel 10.
As shown in fig. 4 and 5, the push rod 20 includes a first push rod portion 21, a second push rod portion 22, and a third push rod portion 23, the second push rod portion 22 being located between the first push rod portion 21 and the third push rod portion 23. The diameter of the first push rod portion 21 is larger than the diameter of the second push rod portion 22. The diameter of the second push rod portion 22 is larger than the diameter of the third push rod portion 23.
The first push rod portion 21 is provided with a first channel 211 and a second channel 212, and the first channel 211 has a bend. The second passage 212 is parallel to the axial direction of the push rod 20. The first passage 211 and the second passage 212 have a communication port therebetween, and the first stopper 15 can switch between the first passage 211 and the second passage 212 through the communication port. The communication port is a predetermined distance from the end of the first push rod portion 21 near the second push rod portion 22.
The first push rod portion 21 has a cavity 213 therein, and by providing the cavity 213, the total weight of the push rod 20 can be reduced, and the cooling molding can be facilitated during the manufacturing process.
The second pushrod portion 22 is an equal diameter section.
The transition position of the third push rod portion 23 and the second push rod portion 22 is provided with a first boss 232 and a second boss 233, and the first boss 232 is located at one side of the second boss 233, which is close to the second push rod portion 22. The first boss 232 and the second boss 233 are integrally connected, and an outer diameter of the first boss 232 is larger than an outer diameter of the second boss 233. The second boss 233 is further provided with a groove 234 on one side far away from the first boss 232, and a third boss is arranged on the inner wall of the inner hole of the piston 30 and embedded into the groove 234, so that the purpose of axially limiting the piston 30 is achieved. Meanwhile, a side of the piston 30 adjacent to the second push rod portion 22 abuts against the second boss 233.
The third push rod portion 23 is further provided with a third limiting portion 231, the outer diameter of the third limiting portion 231 is gradually increased along the direction that the medicine enters the barrel 10, one side, away from the medicine inlet and outlet 18 of the barrel 10, of the third limiting portion 231 is provided with a blocking surface, and the plurality of limiting pieces are opened when the third limiting portion 231 passes through the second limiting portion 16 and contracted to abut against the blocking surface after the third limiting portion 231 passes through the second limiting portion 16. Before the applicator is self-destructed, the push rod 20 can be free to reciprocate through the first channel 211.
The third limiting portion 231 is further provided with a push rod tail portion at a side far away from the second push rod portion 22, and the push rod tail portion is used for enabling all medicines in the barrel 10 to be pushed out of the barrel 10. After the self-destroying structure is started, the tail part of the push rod at least partially extends out of the barrel body 10 so as to ensure that the medicine is discharged. The diameter of the pushrod tail is smaller than the diameter of the second pushrod portion 22.
The push rod 20 further comprises a push handle 24, the push handle 24 being arranged at an end of the first push rod portion 21 remote from the second push rod portion 22. The diameter of the push handle 24 is larger than the diameter of the first push rod portion 21.
The side of the push handle 24 away from the first push rod portion 21 is provided with a slip preventing strip 241 to prevent a slip problem from occurring when a pushing force is applied to the push handle 24.
As shown in fig. 6, the piston 30 includes a portion having an outer diameter approximately equal to an inner diameter of the first chamber 11 to scrape off the medicine adhered to the inner wall of the first chamber 11 through the portion, thereby achieving the exhausting purpose.
In the first state, as shown in fig. 7 and 8, the push rod 20 is in the pulled-out position, and the tail of the push rod on the push rod 20 is retracted into the interior of the barrel 10. At this time, the first stopper 15 is located at the communication port of the first passage 211 and the second passage 212. At this time, the medicine may be drawn into the cylinder 10, or the push rod 20 may be pulled out although the medicine is not drawn into the cylinder 10. At this time, the push rod 20 is not separated from the cylinder 10 by the fourth stopper 17 and the first boss 232.
As shown in fig. 9, 10 and 11, in the second state, the push rod 20 is in the pushed-out position, which is a state in which the medicine is completely pushed out of the cartridge 10. At this time, the self-destruction structure is started, and the third limiting portion 231 passes through the second limiting portion 16 and cannot move in the pulling-out direction of the push rod 20 due to the contact between the blocking surface of the third limiting portion 231 and the contracted limiting piece, so as to realize self-destruction. At this time, one end of the piston 30 abuts against the end of the first chamber 11 close to the connector 14, and the purpose of exhausting the medicine is achieved.
The working process of the drug feeder is as follows:
in the initial state, the push rod 20 is arranged in the cylinder 10, the first limiting part 15 is arranged in the second channel 212, and if the medicine is required to be extracted, the push rod 20 is pulled outwards until the fourth limiting part 17 is contacted with the first boss 232; then, the push rod 20 is rotated to enable the first limiting part 15 to rotate into the first channel 211; then, the push rod 20 is pushed in the axial direction of the cylinder 10 by pressing the push handle 24, and administration is performed. In the process of drug delivery, the first channel 211 slides relative to the cylinder 10 under the limiting action of the first limiting part 15, and when the first channel 211 reaches the bending part, the movement of the push rod 20 is blocked, so that the first quantitative drug delivery is completed; then, the push rod 20 is rotated, so that the first limiting part 15 is bent in a avoiding manner, the push rod 20 is pushed continuously, and when the first limiting part 15 encounters resistance again, the second medicine feeding is completed. If a plurality of bends are arranged in the first channel 211, repeated quantitative administration can be realized, and after the last administration is completed, the third limit part 231 on the push rod 20 and the second limit part 16 on the barrel 10 are matched with each other to realize self-destruction of the administration device, the push rod 20 and the barrel 10 achieve an interlocking effect, and the push rod 20 cannot act again.
According to the embodiment of the invention, quantitative administration can be realized through the cooperation of the first channel 211 arranged on the push rod 20 and the first limit part 15 arranged on the cylinder body 10; by providing a bend in the first channel 211, multiple dosing may be achieved; by means of the second channel 212, a free and rapid reciprocating movement of the push rod 20 can be achieved before self-destruction; by controlling the length of the axial movement of the push rod 20, accurate dosing can be achieved and operation is convenient.
The embodiment of the invention can effectively improve the accuracy and the operation convenience of the dosage and prevent the dosage device from being reused.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention and not for limiting the same; while the invention has been described in detail with reference to the preferred embodiments, those skilled in the art will appreciate that: modifications and equivalents of the features disclosed herein may be made to the specific embodiments of the invention or to parts of the features may be substituted without departing from the principles of the invention, and such modifications and equivalents are intended to be encompassed within the scope of the invention as claimed.

Claims (11)

1. An applicator, comprising:
a cylinder (10) provided with a containing cavity for storing medicines, wherein a first limit part (15) is arranged on the cylinder (10); and
a push rod (20) is slidably engaged with the inner surface of the accommodating cavity, and the push rod (20) is provided with a first channel (211) and a second channel (212), and the first limit part (15) is configured to move in the first channel (211) when the push rod (20) pushes the medicine out of the barrel (10) and move in the second channel (212) when the push rod (20) is pulled outwards to enable the medicine to enter the barrel (10).
2. The applicator according to claim 1, wherein the first channel (211) extends in the axial direction of the push rod (20) and has a bend.
3. The applicator according to claim 1, wherein the second channel (212) is parallel to the axial direction of the push rod (20).
4. The dispenser of claim 1, further comprising a second stop (16) provided to the barrel (10) and a third stop (231) provided to the push rod (20), the second stop (16) and the third stop (231) being configured to cooperate to prevent movement of the push rod (20) in a direction in which the drug enters the barrel (10) after all of the drug has been pushed out of the barrel (10).
5. The dispenser according to claim 4, wherein the second stopper (16) includes a plurality of stopper pieces, first ends of the plurality of stopper pieces are connected to the barrel (10), the plurality of stopper pieces are arranged at intervals in a circumferential direction of the barrel (10) and second ends of the plurality of stopper pieces are inclined in a direction approaching an axis of the barrel (10), an outer diameter of the third stopper (231) is gradually increased in a direction in which the medicine enters the barrel (10), and a side of the third stopper (231) away from the medicine inlet/outlet (18) of the barrel (10) has a blocking surface, and the plurality of stopper pieces are opened when the third stopper (231) passes through the second stopper (16) and are contracted to abut against the blocking surface after the third stopper (231) passes through the second stopper (16).
6. The applicator of any one of claims 1 to 5, wherein a first distance between a trailing end of the first channel (211) proximate the force-applying end of the push rod (20) and the force-applying end of the push rod (20) is greater than a second distance between a trailing end of the second channel (212) proximate the force-applying end of the push rod (20) and the force-applying end of the push rod (20).
7. The applicator of claim 1, further comprising an anti-slip structure configured to prevent the pushrod (20) from exiting the receiving cavity.
8. The dispenser of claim 7, wherein the anti-drop structure comprises a fourth limit portion (17) disposed in the receiving cavity and a first boss (232) disposed in the push rod (20), the first boss (232) having an outer diameter greater than an inner diameter of the fourth limit portion (17).
9. The dispenser of claim 1, further comprising a piston (30), the receiving chamber comprising a first chamber (11) for storing the medicament, the piston (30) being mounted to the push rod (20), and the piston (30) comprising a portion having an outer diameter substantially equal to an inner diameter of the first chamber (11).
10. The dispenser according to claim 9, wherein the push rod (20) is provided with a second boss (233), the piston (30) and the second boss (233) being in abutment with each other in the axial direction of the barrel (10).
11. A method of administering a medicament based on the dispenser of any one of claims 1 to 10, comprising:
rotating the push rod (20) relative to the cylinder (10) so as to enable the first limit part (15) to enter the second channel (212);
pulling the push rod (20) away from the drug inlet (18) of the barrel (10) under the guiding action of the second channel (212) so as to enable the drug to enter the containing cavity;
rotating the push rod (20) relative to the cylinder (10) so as to enable the first limiting part (15) to enter the first channel (211); and
under the guiding action of the first channel (211), the push rod (20) is pushed towards the direction approaching to the medicine inlet and outlet (18) of the barrel (10) so as to push the medicine out of the barrel (10).
CN202210113449.3A 2022-01-30 2022-01-30 Drug delivery device and drug delivery method Pending CN116549779A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210113449.3A CN116549779A (en) 2022-01-30 2022-01-30 Drug delivery device and drug delivery method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210113449.3A CN116549779A (en) 2022-01-30 2022-01-30 Drug delivery device and drug delivery method

Publications (1)

Publication Number Publication Date
CN116549779A true CN116549779A (en) 2023-08-08

Family

ID=87493486

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210113449.3A Pending CN116549779A (en) 2022-01-30 2022-01-30 Drug delivery device and drug delivery method

Country Status (1)

Country Link
CN (1) CN116549779A (en)

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