CN114146257B

CN114146257B - Drug delivery device and drug delivery method

Info

Publication number: CN114146257B
Application number: CN202111653890.2A
Authority: CN
Inventors: 王岳柏; 刘鹏; 王忠义
Original assignee: Zhejiang Jiaoyang Biomedical Technology Co ltd
Current assignee: Zhejiang Jiaoyang Biomedical Technology Co ltd
Priority date: 2021-12-30
Filing date: 2021-12-30
Publication date: 2022-09-23
Anticipated expiration: 2041-12-30
Also published as: CN114146257A

Abstract

The invention relates to a drug delivery device and a drug delivery method, wherein the drug delivery device comprises a barrel body (1) and a push rod (2), the barrel body (1) is provided with a first port (101), a second port (102) and an accommodating cavity (15) communicated with the first port (101) and the second port (102), the first port (101) is used for enabling drugs to flow out, a first limiting part (16) is arranged in the accommodating cavity (15), the push rod (2) is slidably jointed on the inner surface of the accommodating cavity (15) through the second port (102), the push rod (2) is provided with a first blocking part (234), the first blocking part (234) is configured to be contacted with the first limiting part (16) to block the push rod (2) when the push rod (2) slides relative to the barrel body (1), and the push rod (2) has a first state and a second state, in a first state, the first blocking part (234) can be contacted with the first limiting part (16); in the second state, the first stopper (234) and the first stopper (16) are offset relative to each other in the circumferential direction.

Description

Drug delivery device and drug delivery method

Technical Field

The invention relates to the technical field of drug delivery instruments, in particular to a drug delivery device and a drug delivery method.

Background

The syringe is a device widely used in the fields of medical treatment and the like, and the principle of the syringe is that liquid is sucked in and then discharged through a pintle connector. The outer wall of an injection tube of a conventional injector is provided with a measuring ruler, medical staff determines the injection amount of each time by using the measuring ruler, then a piston handle on a piston rod is used for pushing a piston, and a rubber pushing head on the outer edge of the piston pushes liquid medicine in the injection tube into a human body through a needle head.

However, in some special cases, it may be necessary to inject the medicament into a certain part of the human body with great precision. For example, in the treatment of certain diseases of the nasal cavity, it is often necessary to dose a quantity of liquid medicine into the nostril. There are also diseases outside the nasal cavity, and it is also necessary to spray the corresponding medicine in the nasal cavity in a quantitative manner so as to make the medicine inhaled into the body from the nasal cavity. However, the accuracy of conventional syringes is generally difficult to meet injection requirements.

It is noted that the information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information constitutes prior art already known to a person skilled in the art.

Disclosure of Invention

Embodiments of the present invention provide a drug delivery device and a drug delivery method that can effectively improve the accuracy of a dose.

According to a first aspect of the present invention there is provided a drug delivery device comprising:

the drug delivery device comprises a barrel body, a first valve, a second valve and a first valve, wherein the barrel body is provided with a first port, a second port and an accommodating cavity communicated with the first port and the second port, the first port is used for enabling drugs to flow out, and a first limiting part is arranged in the accommodating cavity; and

the push rod is slidably jointed on the inner surface of the accommodating cavity through the second port and is provided with a first blocking part, the first blocking part is configured to be contacted with the first limiting part when the push rod slides relative to the barrel body so as to block the push rod, and the push rod has a first state and a second state, and the first blocking part can be contacted with the first limiting part in the first state; in the second state, the first blocking part and the first limiting part are staggered relatively in the circumferential direction.

In some embodiments, an anti-rotation part is disposed in the accommodating cavity, and the anti-rotation part is configured to prevent the push rod from rotating relative to the barrel body before the first blocking part contacts the first limiting part.

In some embodiments, the drug delivery device further comprises an avoidance feature configured to cause the push rod to avoid the anti-rotation feature when the push rod is rotated relative to the barrel.

In some embodiments, the avoidance structure includes a first avoidance groove disposed on the pushrod, the first avoidance groove extending inwardly from an outer surface of the pushrod, the first avoidance groove configured to allow the anti-rotation component to pass through the first avoidance groove when the pushrod rotates relative to the barrel.

In some embodiments, the push rod is provided with a second avoidance groove, and the second avoidance groove and the first avoidance groove are arranged at intervals along the axial direction of the barrel.

In some embodiments, the push rod comprises a first push plate and a second push plate which are connected with each other and form a preset included angle, the first blocking part is arranged on the side surface of the first push plate and extends along the direction close to the axis of the cylinder, and the avoiding structure is arranged on the second push plate.

In some embodiments, the first position-limiting portion extends from a position approximately flush with the rotation-preventing member to a direction close to the first port along an axial direction of the cylinder, a gap is provided between the first position-limiting portion and the rotation-preventing member, and a width of the gap in a circumferential direction of the cylinder is not less than a thickness of the second push plate.

In some embodiments, the drug delivery device further comprises a guide structure configured to guide the push rod during loading of the push rod into the receiving cavity such that the first stop is located between the first push plate and the second push plate.

In some embodiments, the guide structure includes a boss disposed on an inner surface of the receiving cavity and extending to the second port, the boss being disposed between the first push plate and the second push plate to limit the push rod in a circumferential direction of the barrel.

In some embodiments, a recessed portion is disposed at an end of the second push plate close to the second port, and the recessed portion is configured to avoid the boss, so that the push rod can rotate relative to the barrel body after reaching a position where the first blocking portion contacts with the first limiting portion.

In some embodiments, a distance between an end of the recess distal from the second port and the bypass structure is less than a distance between the anti-rotation member and the boss.

In some embodiments, a second limiting portion located on one side of the first limiting portion away from the second port is arranged in the accommodating cavity, the push rod is provided with a second blocking portion located on one side of the first blocking portion away from the second port, and the second limiting portion is in contact with the second blocking portion to prevent the push rod from sliding relative to the barrel.

In some embodiments, the drug delivery device further comprises a sealing plug, the sealing plug is mounted at the end of the push rod, the sealing plug is tightly matched with the inner surface of the accommodating cavity, a third limiting part is arranged in the accommodating cavity, and a fourth limiting part matched with the third limiting part is arranged on the outer surface of the sealing plug.

According to a second aspect of the present invention, there is provided a method of administering a drug based on the above drug delivery device, comprising:

the push rod is pushed to slide relative to the cylinder body, and when the first blocking part is contacted with the first limiting part, the first administration is finished;

rotating the push rod to relatively stagger the first blocking part and the first limiting part in the circumferential direction; and

and continuously pushing the push rod to slide relative to the cylinder body until the second administration is finished.

Based on the technical scheme, in the embodiment of the invention, the first limiting part is arranged in the accommodating cavity of the barrel, the push rod is provided with the first blocking part, and the push rod has two states, when the push rod is in the first state, the first blocking part can be contacted with the first limiting part in the sliding process of the push rod relative to the barrel, so that the push rod is prevented from continuously moving, the first administration is realized, and in the first administration process, the push rod stops moving through the mutual contact of the first blocking part and the first limiting part, so that the administration amount can be accurately controlled, and the administration accuracy is effectively improved; and when the push rod is in the second state, the first blocking part and the first limiting part are staggered relatively in the circumferential direction, so that the push rod can continuously slide relative to the barrel to finish the second administration, and the medicine feeding device is suitable for a scene needing at least twice administration.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the invention without limiting the invention. In the drawings:

fig. 1 is a schematic view of the cartridge in an embodiment of the drug delivery device according to the invention.

Figure 2 is a front view of a cartridge in an embodiment of a drug delivery device according to the invention.

Fig. 3 is a cross-sectional view of the cartridge taken along section a-a in the embodiment of fig. 2.

Fig. 4 is a schematic view of a push rod in an embodiment of a drug delivery device according to the invention.

Fig. 5 is a front view of a push rod in an embodiment of a drug delivery device according to the invention.

Fig. 6 is a cross-sectional view of the cartridge taken along section B-B in the embodiment of fig. 2.

Fig. 7 is a schematic view of a sealing plug in an embodiment of the drug delivery device according to the invention.

In the figure:

1. a barrel; 2. a push rod; 3. a sealing plug;

11. an installation part; 12. a first barrel portion; 13. a second barrel portion; 14. a hand-held portion; 15. an accommodating chamber; 151. a first accommodating portion; 152. a second accommodating portion; 153. a third accommodating portion; 16. a first limiting part; 17. an anti-rotation member; 18. a boss; 19. a second limiting part; 10. a third limiting part; 101. a first port; 102. a second port;

21. a club head; 22. a push rod extension; 23. a push rod body; 231. a first push plate; 232. a second push plate; 233. a third push plate; 234. a first blocking portion; 235. a first avoidance slot; 236. a second avoidance slot; 237. a spacer section; 238. a recessed portion; 24. a pressing section; 25. a second blocking portion;

31. a plug body; 311. a fourth limiting part; 32. and a tail portion.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "central," "lateral," "longitudinal," "front," "rear," "left," "right," "upper," "lower," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientations and positional relationships indicated in the drawings, which are based on the orientations and positional relationships indicated in the drawings, and are used for convenience in describing the present invention and to simplify the description, but are not intended to indicate or imply that the device or element so referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and therefore should not be construed as limiting the scope of the present invention.

Referring to fig. 1 to 6, in some embodiments of the drug delivery device provided by the present invention, the drug delivery device includes a barrel 1 and a push rod 2, the barrel 1 is provided with a first port 101, a second port 102 and a receiving cavity 15 communicating with the first port 101 and the second port 102, the first port 101 is used for allowing a drug to flow out, a first stopper 16 is provided in the receiving cavity 15, the push rod 2 is slidably coupled to an inner surface of the receiving cavity 15 through the second port 102, the push rod 2 is provided with a first stopper 234, the first stopper 234 is configured to contact with the first stopper 16 when the push rod 2 slides relative to the barrel 1 to block the push rod 2, and the push rod 2 has a first state and a second state, in the first state, the first stopper 234 can contact with the first stopper 16; in the second state, the first stopper 234 and the first stopper 16 are relatively displaced in the circumferential direction.

In the above embodiment, the accommodating cavity 15 of the barrel 1 is internally provided with the first limiting part 16, the push rod 2 is provided with the first blocking part 234, and the push rod 2 has two states, when the push rod 2 is in the first state, the first blocking part 234 can contact with the first limiting part 16 in the process that the push rod 2 slides relative to the barrel 1, so as to prevent the push rod 2 from continuing to move, and realize first administration, and in the first administration process, the push rod 2 stops moving through the mutual contact of the first blocking part 234 and the first limiting part 16, so that the administration amount can be accurately controlled, and the administration accuracy is effectively improved.

When the push rod 2 is in the second state, the first blocking portion 234 and the first limiting portion 16 are relatively staggered in the circumferential direction, so that the push rod 2 can continuously slide relative to the cylinder 1, and the second administration is completed. For some scenes that the medicine needs to be administered to the same patient at least twice, the medicine administration device provided by the invention can realize continuous twice administration without replacing a new medicine administration device during the second time administration, thereby avoiding the waste of resources.

In some embodiments, the push rod 2 is configured to rotate relative to the barrel 1 to effect transition of the push rod 2 between the first state and the second state.

Realize the switching of push rod 2 between two states through the pivoted mode, can have a difference with push rod 2 when dosing for the sliding motion mode of barrel 1, avoid taking place the confusion between action and the state switching action of dosing of push rod 2, effectively improve the motion reliability of moving part in the device of dosing, be favorable to improving the device of dosing's the efficiency of dosing simultaneously.

As shown in fig. 3, in some embodiments, an anti-rotation part 17 is disposed in the accommodating cavity 15, and the anti-rotation part 17 is configured to prevent the push rod 2 from rotating relative to the barrel 1 before the first blocking part 234 contacts the first limiting part 16.

Through setting up the anti-rotation part 17, can prevent that the state of push rod 2 from changing in advance, avoid first barrier part 234 and first spacing portion 16 can't contact each other according to the mode of predesign, destroy the structural design who doses for the first time, influence the accuracy of dosing for the first time.

In some embodiments, the drug delivery device further comprises an avoidance structure configured to cause the push rod 2 to avoid the anti-rotation feature 17 when the push rod 2 is rotated relative to the barrel 1.

Through setting up and dodging the structure, can remove the rotation restriction effect of preventing that rotational component 17 is to push rod 2 for push rod 2 can rotate for barrel 1 when getting into the second state.

The specific structure form of the avoiding structure can be selected in various ways.

As shown in fig. 4 to 6, in some embodiments, the avoiding structure includes a first avoiding groove 235 provided in the push rod 2, the first avoiding groove 235 extending inward from the outer surface of the push rod 2, the first avoiding groove 235 being configured to allow the rotation preventing member 17 to pass through the first avoiding groove 235 when the push rod 2 rotates relative to the barrel 1.

Through setting up first dodge the groove 235, can make prevent that the part 17 passes first dodge the groove 235, remove promptly and prevent that the part 17 prevents to push rod 2's rotation restriction effect.

In some embodiments, the push rod 2 is provided with a second avoiding groove 236, and the second avoiding groove 236 and the first avoiding groove 235 are arranged at intervals in the axial direction of the barrel 1.

Through setting up second dodge groove 236, can regard as the reserve of first dodge groove 235, when first dodge groove 235 because of manufacturing error or because some reasons are blockked up, can make prevent that rotational component 17 passes second dodge groove 236 and realize the relative rotation of push rod 2 and barrel 1.

In some embodiments, the second avoidance slot 236 is located on a side of the first avoidance slot 235 proximate the second port 102. When the push rod 2 is drawn out of the cylinder 1, the push rod 2 can be rotated relative to the cylinder 1 by passing the rotation preventing member 17 through the second avoiding groove 236, and since the second avoiding groove 236 is located at a side of the first avoiding groove 235 close to the second port 102, when the push rod 2 is drawn out, the second avoiding groove 236 meets the rotation preventing member 17 earlier than the first avoiding groove 235, and the relative rotation between the push rod 2 and the cylinder 1 can be realized more quickly.

In some embodiments, the distance between the anti-rotation member 17 and the second port 102 is substantially equal to the distance between the end of the first stopper portion 16 near the second port 102 and the second port 102. The advantage that sets up like this is, after first barrier portion 234 and first spacing portion 16 contact, can make prevent that the part 17 just in time aligns with first dodge groove 235, can directly rotate push rod 2, and need not move push rod 2 forward or backward, can effectively improve the efficiency of dosing device.

As shown in fig. 5, in some embodiments, the push rod 2 includes a first push plate 231 and a second push plate 232 connected to each other and having a predetermined included angle, a first blocking portion 234 is disposed at a side of the first push plate 231 and extends in a direction close to the axis of the barrel 1, and an avoiding structure is disposed at the second push plate 232.

The first pushing plate 231 and the second pushing plate 232 intersect at a predetermined angle, and a predetermined space is formed between the first pushing plate 231 and the second pushing plate 232, so that the first limiting portion 16 is located between the first pushing plate 231 and the second pushing plate 232.

In some embodiments, the first position-limiting part 16 extends from a position approximately flush with the rotation-preventing part 17 to a direction close to the first port 101 along the axial direction of the cylinder 1, a gap is formed between the first position-limiting part 16 and the rotation-preventing part 17, and the width of the gap in the circumferential direction of the cylinder is not less than the thickness of the second push plate 232. The arrangement can ensure that the second push plate 232 can enter the gap between the first limiting part 16 and the anti-rotation part 17 after the push rod 2 rotates, and the second push plate 232 can continuously slide along with the push rod 2 in the gap.

In some embodiments, the drug delivery device further comprises a guiding structure configured to guide the push rod 2 such that the first stopper portion 16 is located between the first and

second push plates

231 and 232 during loading of the push rod 2 into the receiving cavity 15.

Through setting up guide structure, can make push rod 2 get into and hold chamber 15 with the gesture that first spacing portion 16 is located between first push plate 231 and the second push plate 232 when packing into holding chamber 15 with push rod 2, avoid the installation dislocation. The guide structure can assist the installation of the push rod 2, and effectively improves the installation efficiency. Meanwhile, at the initial stage when the push rod 2 just enters the accommodating cavity 15, the guide structure can also guide the movement of the push rod 2, so that the movement of the push rod 2 is prevented from deflecting.

As shown in fig. 3, in some embodiments, the guide structure includes a boss 18 disposed on the inner surface of the receiving cavity 15 and extending to the second port 102, the boss 18 being disposed between the first push plate 231 and the second push plate 232 to limit the push rod 2 in the circumferential direction of the cartridge 1.

By providing the boss 18 between the first pushing plate 231 and the second pushing plate 232, the push rod 2 can be limited in the circumferential direction of the cartridge 1, so that the push rod 2 enters the accommodating chamber 15 in a predetermined posture.

In some embodiments, the push rod 2 may comprise 4 push plates, and accordingly the number of bosses 18 may also be 4.

As shown in fig. 5 and 6, in some embodiments, an end of the second push plate 232 close to the second port 102 is provided with a recessed portion 238, and the recessed portion 238 is configured to avoid the boss 18, so that the push rod 2 can rotate relative to the barrel 1 after reaching a position where the first blocking portion 234 contacts the first limiting portion 16.

The recess 238 extends from the end of the push rod 2 in a direction towards the escape structure.

By providing the recess 238, the rotation restriction of the second push plate 232 by the boss 18 can be released after the push rod 2 is fitted into the accommodation chamber 15 by a predetermined length.

In some embodiments, the distance between the end of the recess 238 remote from the second port 102 and the bypass structure is less than the distance between the anti-rotation member 17 and the boss 18. This has the advantage of allowing the second push plate 232 to rotate relative to the cartridge 1.

In some embodiments, a second position-limiting part 19 is disposed in the accommodating cavity 15 on a side of the first position-limiting part 16 away from the second port 102, the push rod 2 is provided with a second blocking part 25 on a side of the first blocking part 234 away from the second port 102, and the second position-limiting part 19 contacts with the second blocking part 25 to prevent the push rod 2 from sliding relative to the barrel 1.

Through setting up second spacing portion 19 and second stopper 25, can block push rod 2 through the contact of second spacing portion 19 and second stopper 25 when dosing for the second time, realize the accurate control of dose for the second time, improve the accuracy of dosing for the second time.

As shown in fig. 7, in some embodiments, the drug delivery device further includes a sealing plug 3, the sealing plug 3 is mounted on the end portion of the push rod 2, the sealing plug 3 is tightly fitted with the inner surface of the accommodating cavity 15, a third position-limiting portion 10 is arranged in the accommodating cavity 15, and a fourth position-limiting portion 311 fitted with the third position-limiting portion 10 is arranged on the outer surface of the sealing plug 3.

By providing the sealing plug 3, a sealing fit with the inner surface of the receiving cavity 15 can be achieved, and leakage of liquid can be prevented. Can also strike off the medicine of adhesion at the internal surface that holds chamber 15 clean when dosing through sealing plug 3, avoid the medicine to remain, effectively improve the accuracy of dose.

Through the third limiting part 10 and the fourth limiting part 311, when medicine is extracted or pushed, certain resistance can be formed on the movement of the push rod 2 through the matching of the third limiting part 10 and the fourth limiting part 311, and prompt information about the movement position of the push rod 2 is provided for a user.

For example, by providing the third limiting portion 10 and the fourth limiting portion 311, the amount of the medicine sucked by the medicine delivery device before medicine delivery can reach the preset value, for example, when the third limiting portion 10 and the fourth limiting portion 311 contact and the push rod 2 is pulled to receive resistance, the amount of the medicine sucked by the medicine delivery device meets the preset requirement, and at this time, the user can stop sucking the medicine.

The third position-limiting portion 10 may be an annular structure or one or more convex strips independently arranged along the circumferential direction. The fourth limiting portion 311 may also be an annular structure or one or more convex strips independently arranged along the circumferential direction.

In some embodiments, the sealing plug 3 has elasticity, which is beneficial to achieve a tight fit with the inner surface of the accommodating cavity 15, and also can enable the third limiting part 10 and the fourth limiting part 311 to overcome the resistance of the third limiting part 10 and the fourth limiting part 311 to the push rod 2 by applying a larger external force after the third limiting part 10 and the fourth limiting part 311 are contacted, so as to prevent the third limiting part 10 and the fourth limiting part 311 from completely preventing the movement of the push rod 2.

In some embodiments, the sealing plug 3 is made of a rubber material.

In some embodiments, the drug delivery device further comprises a needle or guard plug removably attached to the barrel 1 at the first port 101, the needle being used to inject a liquid to a predetermined site, and the guard plug being supportable in a nasal cavity or the like.

Based on the drug delivery device in each of the above embodiments, the present invention also provides a drug delivery method, including:

the push rod 2 is pushed to slide relative to the barrel 1, and when the first blocking part 234 is contacted with the first limiting part 16, the first administration is finished;

rotating the push rod 2 to relatively shift the first blocking part 234 and the first limiting part 16 in the circumferential direction; and

the push rod 2 is pushed to slide relative to the cylinder body 1 continuously until the second administration is finished.

In some embodiments, before pushing the push rod 2 to slide relative to the barrel 1, the method of administering the drug further comprises:

the push rod 2 is slidably engaged with the inner surface of the accommodating chamber 15 through the second port 102.

The positive technical effects of the drug delivery device in the various embodiments described above are equally applicable to the method of drug delivery and will not be described in detail here.

The administration device and the administration method provided by the invention can be suitable for liquid medicines, powdery solid medicines or solid-liquid mixed medicines, can be suitable for being injected into a human body, and can also be suitable for being sprayed to certain parts of the human body.

The structure and operation of one embodiment of the drug delivery device of the present invention will now be described with reference to figures 1 to 7 of the accompanying drawings:

as shown in fig. 1 to 3, the barrel 1 is a cylindrical structure, the barrel 1 is a stepped structure, the barrel 1 includes a mounting portion 11, a first barrel portion 12, a second barrel portion 13 and a holding portion 14, the mounting portion 11 has a diameter smaller than that of the first barrel portion 12, and the first barrel portion 12 has a diameter smaller than that of the second barrel portion 13. The hand-held portion 14 is attached to an end of the second barrel portion 13 remote from the first barrel portion 12.

The accommodating chamber 15 is arranged inside the cylinder 1, the accommodating chamber 15 includes a first accommodating portion 151, a second accommodating portion 152 and a third accommodating portion 153, the first accommodating portion 151 is arranged inside the mounting portion 11, the second accommodating portion 152 is arranged inside the first cylinder portion 12, and the third accommodating portion 153 is arranged inside the second cylinder portion 13. The first receiving portion 151 has a diameter smaller than that of the second receiving portion 152, and the second receiving portion 152 has a diameter smaller than that of the third receiving portion 153. The second receiving portion 152 is used to store medicine, and the second receiving portion 152 and the third receiving portion 153 are used to receive the push rod 2.

The end of the first housing part 151 away from the second housing part 152 forms the first port 101 of the cylinder 1, the third housing part 153 extends to the end of the handle part 14 away from the second cylinder part 13, and the end of the third housing part 153 away from the second housing part 152 forms the second port 102 of the cylinder 1.

The first position-limiting portion 16 is disposed in the third accommodating portion 153, and the first position-limiting portion 16 extends from an end portion of the third accommodating portion 153 close to the second accommodating portion 152 to a direction close to the second port 102. The first position-limiting portion 16 is in the shape of an elongated cylinder, and may be a cylinder, a triangular prism, a quadrangular prism, or the like. A support portion for mounting the first stopper portion 16 may be provided in the third receiving portion 153.

The rotation-preventing member 17 is of a small-projection structure. The rotation preventing member 17 is provided on an inner surface of the third accommodating portion 153. A gap is provided between the rotation preventing member 17 and the first stopper portion 16.

The diameter changing portions of the first barrel portion 12 and the second barrel portion 13 form a second stopper portion 19. The third position-limiting portion 10 is disposed in the second accommodating portion 152 and is close to the first accommodating portion 151. The third stopper portion 10 may be provided at a position capable of storing a dose required for two administrations.

The third receiving portion 153 is provided with 4 bosses 18 arranged at intervals in the circumferential direction at a position close to the second port 102. The boss 18 is in the shape of a long bar. The boss 18 has a length in the axial direction slightly greater than the thickness of the hand grip 14 in the axial direction.

In the circumferential direction, two first stopper portions 16 and two rotation preventing members 17 may be provided in the third accommodating portion 153, which are symmetrically arranged.

As shown in fig. 4 to 6, the putter 2 includes a putter head 21, a putter extension 22, a putter body 23, and a pressing portion 24, and the putter head 21, the putter extension 22, the putter body 23, and the pressing portion 24 are connected in this order and integrally formed. The pushing portion 24 is of a flat plate structure and is attached to an end portion of the push rod body 23. The length of the push rod extension 22 is substantially equal to the length of the second receiving portion 152.

The push rod extension part 22 comprises 4 extension rods which are connected with each other, an included angle of 90 degrees is formed between any two adjacent extension rods, and the cross section of the push rod extension part 22 along the direction vertical to the axis of the push rod 2 is in a cross shape.

The push rod body 23 comprises a first push plate 231, a second push plate 232, a third push plate 233 and a fourth push plate which are connected with each other, an included angle of 90 degrees is formed between any two adjacent push plates, and the cross section of the push rod body 23 along the direction vertical to the axis of the push rod 2 is in a cross shape.

The first push plate 231 is provided with a first blocking portion 234, the first blocking portion 234 is in a bump structure, the first blocking portion 234 protrudes out of the surface of the first push plate 231, and the first blocking portion 234 has a preset height in a direction perpendicular to the first push plate 231.

The second pushing plate 232 is provided with a first avoiding groove 235 and a second avoiding groove 236, and the openings of the first avoiding groove 235 and the second avoiding groove 236 face a direction away from the center line of the push rod 2. A spacer 237 is formed between the first escape groove 235 and the second escape groove 236.

The second push plate 232 is provided with a recess 238 at a position close to the second port 102, and the recess 238 extends to the pushing part 24.

The diameter of the push rod extension 22 is smaller than the diameter of the push rod body 23. The diameter change of the push rod extension 22 and the push rod body 23 forms a second stopper 25.

The third push plate 233 may be provided with a first blocking portion 234, similarly to the first push plate 231. The fourth push plate may be similar to the second push plate 232 and also provided with a first avoidance groove 235, a second avoidance groove 236, a spacer 237, and a recess 238.

As shown in fig. 7, the sealing plug 3 includes a plug body 31 and a tail portion 32, and a fourth limiting portion 311 is disposed on the plug body 31. The sealing plug 3 is mounted on the stem head 21. After the plunger 2 is inserted into the receiving cavity 15, the sealing plug 3 is located in the second receiving portion 152, and the tail portion 32 is located in the first receiving portion 151. The tail portion 32 has a diameter smaller than that of the first accommodation portion 151. The length of the tail part 32 is greater than that of the first accommodating part 151, so that the medicine in the accommodating cavity 15 can be pushed out by the push rod 2, and medicine residue is avoided.

In the design stage, the height of the first stopper 16 may be determined according to the first dose of the drug delivery device, and the height of the second barrel 13 may be determined according to the second dose of the drug delivery device.

The application process of the administration device in this embodiment is (taking the example of liquid medicine into nasal cavity):

connecting a detachable needle head to a mounting part 11 of a barrel body 1 of the drug delivery device, and sucking the drug liquid from the drug bottle to a position where a fourth limiting part 311 on a sealing plug 3 is in contact with a third limiting part 10 on the barrel body 1; then, the needle head of the mounting part 11 is replaced by a nasal cavity protective plug body, the push rod 2 is pushed to carry out first dosing, and when the first blocking part 234 of the push rod 2 abuts against the first limiting part 16 in the barrel body 1, first dosing is finished; then, the push rod 2 is rotated, the rotation-preventing part 17 passes through the first avoiding groove 235 in the rotation process, the second push plate 232 is rotated to a position between the first limiting part 16 and the rotation-preventing part 17 after the rotation, the first blocking part 234 and the first limiting part 16 are staggered in the circumferential direction, the push rod 2 is continuously pushed until the liquid medicine is completely extruded, and the second quantitative administration is completed.

Through the description of the embodiment of the drug delivery device, the embodiment of the drug delivery device can realize two times of continuous dosing, the accuracy of the dose is high, and the operation is convenient.

Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention and not to limit it; although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art will understand that: modifications to the specific embodiments of the invention or equivalent substitutions for parts of the technical features may be made without departing from the principles of the invention, and these modifications and equivalents are intended to be included within the scope of the claims.

Claims

1. A drug delivery device, comprising:

the drug delivery device comprises a barrel body (1) and a first and second drug delivery device, wherein the barrel body is provided with a first port (101), a second port (102) and an accommodating cavity (15) communicated with the first port (101) and the second port (102), the first port (101) is used for enabling drugs to flow out, and a first limiting part (16) is arranged in the accommodating cavity (15); and

a push rod (2) slidably engaged with an inner surface of the housing chamber (15) through the second port (102), the push rod (2) being provided with a first blocking portion (234), the first blocking portion (234) being configured to contact with the first stopper portion (16) to block the push rod (2) when the push rod (2) slides relative to the barrel (1), and the push rod (2) having a first state in which the first blocking portion (234) is contactable with the first stopper portion (16) and a second state; in the second state, the first blocking portion (234) and the first stopper portion (16) are relatively staggered in the circumferential direction;

an anti-rotation part (17) is arranged in the accommodating cavity (15), and the anti-rotation part (17) is configured to prevent the push rod (2) from rotating relative to the barrel body (1) before the first blocking part (234) is contacted with the first limiting part (16);

the drug delivery device further comprises an avoidance structure configured to cause the push rod (2) to avoid the anti-rotation part (17) when the push rod (2) rotates relative to the barrel (1);

the push rod (2) comprises a first push plate (231) and a second push plate (232) which are connected with each other and form a preset included angle, the first blocking portion (234) is arranged on the side face of the first push plate (231) and extends along the direction close to the axis of the cylinder body (1), the avoiding structure is arranged on the second push plate (232), the second push plate (232) extends along the direction of the axis of the cylinder body (1), and the second push plate (232) and the anti-rotating part (17) are matched with each other to limit the push rod (2) to rotate relative to the cylinder body (1) in the circumferential direction;

the first limiting part (16) extends from a position approximately flush with the rotation-preventing part (17) to a direction close to the first port (101) along the axial direction of the cylinder body (1) so as to limit the push rod (2) to rotate relative to the cylinder body (1) in the circumferential direction;

a gap is formed between the first limiting part (16) and the anti-rotation part (17), and the width of the gap in the circumferential direction of the cylinder body is not smaller than the thickness of the second push plate (232).

2. The drug delivery device according to claim 1, wherein the avoidance structure comprises a first avoidance groove (235) provided to the push rod (2), the first avoidance groove (235) extending inwardly from an outer surface of the push rod (2), the first avoidance groove (235) being configured to allow the rotation prevention member (17) to pass through the first avoidance groove (235) when the push rod (2) rotates relative to the barrel (1).

3. The drug delivery device according to claim 2, characterized in that the push rod (2) is provided with a second avoidance groove (236), and the second avoidance groove (236) and the first avoidance groove (235) are arranged at intervals in the axial direction of the barrel (1).

4. The drug delivery device according to claim 1, further comprising a guide structure configured to guide the push rod (2) such that the first stopper portion (16) is located between the first push plate (231) and the second push plate (232) during loading of the push rod (2) into the housing cavity (15).

5. The drug delivery device according to claim 4, characterized in that the guide structure comprises a boss (18) provided on an inner surface of the accommodation chamber (15) and extending to the second port (102), the boss (18) being provided between the first push plate (231) and the second push plate (232) to restrain the push rod (2) in a circumferential direction of the cartridge (1).

6. The drug delivery device according to claim 5, characterized in that the second push plate (232) is provided with a recess (238) at an end thereof adjacent to the second port (102), the recess (238) being configured to avoid the boss (18) so that the push rod (2) can rotate relative to the barrel (1) after reaching a position where the first blocking portion (234) contacts the first stopper portion (16).

7. The drug delivery device according to claim 6, characterized in that the distance between the end of the recess (238) remote from the second port (102) and the bypass structure is smaller than the distance between the anti-rotation member (17) and the boss (18).

8. The drug delivery device according to any one of claims 1 to 7, characterized in that a second limiting part (19) is arranged in the accommodating cavity (15) and is positioned on the side of the first limiting part (16) far away from the second port (102), the push rod (2) is provided with a second stopping part (25) which is positioned on the side of the first stopping part (234) far away from the second port (102), and the second limiting part (19) is contacted with the second stopping part (25) to prevent the push rod (2) from sliding relative to the barrel (1).

9. The drug delivery device according to claim 1, further comprising a sealing plug (3), wherein the sealing plug (3) is mounted at the end of the push rod (2), the sealing plug (3) is tightly matched with the inner surface of the accommodating cavity (15), a third limiting part (10) is arranged in the accommodating cavity (15), and a fourth limiting part (311) matched with the third limiting part (10) is arranged on the outer surface of the sealing plug (3).