CN1165316C - Method for preparing nanometer level pearli powder - Google Patents
Method for preparing nanometer level pearli powder Download PDFInfo
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- CN1165316C CN1165316C CNB011322136A CN01132213A CN1165316C CN 1165316 C CN1165316 C CN 1165316C CN B011322136 A CNB011322136 A CN B011322136A CN 01132213 A CN01132213 A CN 01132213A CN 1165316 C CN1165316 C CN 1165316C
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- margarita
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- pearl powder
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Abstract
The present invention relates to a method for preparing nanometer level pearl powder, which comprises the following steps: lactic acid water solution is used as solvent to dissolve pearls; the pH value of the solution is adjusted to neutrality; the hydrolyzed pearl solution is made into a colloid, and the size of the granule diameter of the pearl powder can reach a nanometer level; the hydrolyzed pearl colloid is rapidly dried by an atomized drying process; the dried colloid is solidified and granulated, and the spherical pearl powder with the size of the average granule diameter of 90 to 100 nanometers is obtained. The prepared nanometer pearl powder reserves effective nutrient components in the pearls, such as various amino acids, various trace elements, etc., and also converts calcium carbonate in the pearls to activated calcium capable of being easily absorbed by a human body. The method for preparing nanometer level pearl powder has the advantages of high efficiency, small energy consumption and low production cost and is suitable for the industrial production of the products of medicine, nutrition and facial beautification.
Description
Technical field
The present invention relates to the ultra micro preparation method of Margarita powder.
Background technology
Modern science the analysis showed that, contains trace element, protein and a large amount of calcium of 20 several amino acids and needed by human body in the Margarita, is a kind of famous and precious Chinese crude drug and nutrient and healthcare products.But Margarita has hard concentric laminated construction, is processed into quite difficulty of powder.Traditional processing method normally earlier Margarita is boiled in water many times softening up to it, and then levigate in water; Or directly Margarita is added water with general Roughpulverizer fragmentation after, the reuse ball mill is pulverized the back and is dried adding under the water state.Because Margarita is boiled bubble for a long time in water, nutritional labeling in the Margarita is damaged or dissolves, aminoacid generally has only 3～6 kinds after testing, the product mean diameter is big simultaneously, how more than 15 microns, absorbance for oral administration or outer time spent the intestines and stomach and skin is low, generally has only 23～29%, and drug effect and health care, cosmetic result are affected.Theory analysis shows, reaches nanoscale and work as the Margarita ultrafine powder particle diameter, during much smaller than skin pore diameter (about 2 μ m), can directly be absorbed by skin, and absorbance for oral administration can significantly improve.
In recent years, for improving the medicinal and nourishing healthy effect of Margarita, domestic many manufacturers have utilized superfine techniques such as airflow milling, colloid mill, vibromill, ultrasonic grinding mill to develop Margarita ultrafine powder.But the mean diameter of these Margarita ultrafine powders still is a micron order, and generally about 3～8 μ m, the energy consumption of the course of processing is very big simultaneously, and production cost is higher.And that Margarita powder mean diameter size reaches nano level ultra micro production technology is still untapped so far.
Summary of the invention
The purpose of this invention is to provide the method that a kind of low-cost production grain size reaches nanometer pearl powder.
The preparation method of nanometer pearl powder provided by the invention in turn includes the following steps:
1) with concentration (by weight) is 2～10% lactic acid aqueous solution dissolved pearl, obtains concentration (by weight) and be 2～15% pearl powder solution;
2) with sodium bicarbonate the pH value of said hydrolyzed Margarita solution is adjusted to neutrality, under 2～10 ℃ of temperature, leaves standstill, the Margarita powder colloid, make the grain size of Margarita powder reach nanoscale;
3) with Margarita powder colloid drying, solidify pelletize, get nanometer Margarita powder.
Usually,, avoid Margarita powder too to grow up, to adopt centrifugal spray drying, fast setting, pelletize for well for making the rapid draing of nanometer Margarita powder colloid.Generally make the pH value of hydrolyzed pearl solution be adjusted to 7.The grain size of Margarita powder is 90～100nm.
The inventive method and the routine of Margarita powder become powder and micropowder to be broken into the powder method to compare and have the following advantages:
1) Margarita powder nutritional labeling utilization rate height.The inventive method adopts edible lactic acid to the Margarita hydrolysis, to the several amino acids that contained in the Margarita, trace element etc. effectively nutritional labeling do not have destruction substantially, and the calcium carbonate in the Margarita can be converted into the activated calcium that human body absorbs easily; Simultaneously, after the Margarita powder particle diameter reached nanorize, the efficient that the effective nutritional labeling in the Margarita is absorbed by the body significantly improved.In addition, the Margarita hydrolysis and make colloid after, can add required special dietary composition therein, produce the Margarita powder product of new and effective energy.
2) Margarita powder ultramicronising.The inventive method adopts the colloidization technology, can realize the nanorize of Margarita powder from yardstick, adopt spray drying technology with the rapid draing of hydrolyzed pearl colloid, pelletize subsequently, again solidify, making outward appearance is the Margarita ultrafine ultramicropowder of 90-100nm for spherical, grain size, is broken into powder (3-8 μ m) method far below Margarita powder conventional one-tenth powder (15 μ m) and micropowder.
3) low energy consumption, production cost is low.Owing to adopted rare lactic acid hydrolysis and spray-drying process, can high efficiency, low energy consumption ground continuous production nanometer Margarita powder, production cost is low.
4) versatility is wide.The nano-pearl powder producing method that the present invention proposes has good versatility applicable to the exploitation and the production of traditional medicine, health promoting product.
The method for preparing nanometer Margarita powder provided by the invention is applicable to the production of medicine, nutrition and health and beauty care product.
Description of drawings
Accompanying drawing is the nanometer pearl powder electromicroscopic photograph that adopts the inventive method to make.
The specific embodiment
Embodiment
With the Margarita stirring and dissolving, obtain concentration (by weight) and be 2.5% pearl powder solution, with the lactic acid aqueous solution of concentration (by weight) 2.5% with sodium bicarbonate (NaHCO
3) regulate above-mentioned solution to pH=7, after leaving standstill 24 hours under 5 ℃ of temperature, get the Margarita powder colloid, make Margarita powder reach nanoscale dimensionally.Adopt the centrifugal spray dryer drying method, the Margarita powder colloid is injected in the hothouse of 100 ℃ of temperature, make the rapid draing of Margarita colloid, pelletize, make particle diameter 90～100nm Margarita powder.Adopt nanometer pearl powder that the inventive method makes as shown in Figure 1, outward appearance is sphere and elliposoidal.
Claims (3)
1. the preparation method of nanometer pearl powder in turn includes the following steps:
1) with concentration (by weight) is 2～10% lactic acid aqueous solution dissolved pearl, obtains concentration (by weight) and be 2～15% pearl powder solution;
2) with sodium bicarbonate the pH value of said hydrolyzed Margarita solution is adjusted to neutrality, under 2～10 ℃ of temperature, leaves standstill, the Margarita powder colloid, make the grain size of Margarita powder reach nanoscale;
3) with Margarita powder colloid drying, solidify pelletize, get nanometer Margarita powder.
2. the preparation method of nanometer pearl powder according to claim 1, the grain size that it is characterized in that Margarita powder is 90～100nm.
3. the preparation method of nanometer pearl powder according to claim 1 is characterized in that the colloidal drying of Margarita powder, adopts the centrifugal spray drying method, fast setting, pelletize.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011322136A CN1165316C (en) | 2001-11-13 | 2001-11-13 | Method for preparing nanometer level pearli powder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011322136A CN1165316C (en) | 2001-11-13 | 2001-11-13 | Method for preparing nanometer level pearli powder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1351869A CN1351869A (en) | 2002-06-05 |
| CN1165316C true CN1165316C (en) | 2004-09-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011322136A Expired - Fee Related CN1165316C (en) | 2001-11-13 | 2001-11-13 | Method for preparing nanometer level pearli powder |
Country Status (1)
| Country | Link |
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| CN (1) | CN1165316C (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1732895B (en) * | 2004-08-12 | 2010-05-12 | 浙江山下湖珍珠集团股份有限公司 | Nanometer grade pearl cream |
| CN1732996B (en) * | 2004-08-12 | 2010-05-26 | 浙江山下湖珍珠集团股份有限公司 | Oral liquid containing nanometer grade pearl powder |
| CN100388981C (en) * | 2005-05-12 | 2008-05-21 | 浙江长生鸟珍珠生物科技有限公司 | Method for preparing full natural Nano pearl powder |
| CN100425245C (en) * | 2006-01-17 | 2008-10-15 | 李伊为 | A method for preparing nano-grade pure pearl powder |
| CN101966140B (en) * | 2010-10-28 | 2012-07-25 | 浙江欧诗漫集团德清生物科技有限公司 | Method for preparing fishy smell removed submicron pearl powder with regular geometric shape |
| CN102744136B (en) * | 2012-07-13 | 2014-04-30 | 四川厚德医药科技有限公司 | Preparation method for nanometre pearl powder and prepared nanometer pearl powder |
| CN104905242B (en) * | 2014-03-14 | 2017-06-13 | 浙江欧诗漫生物股份有限公司 | It is a kind of that the method for preparing the solvable edible calcium of pearl and pearl composite whitening factor solutions is separated from pearl |
| CN105055451A (en) * | 2015-08-18 | 2015-11-18 | 爱斯特（无锡）生物工程有限公司 | Preparation method of water-soluble pearl powder |
| CN105796466B (en) * | 2016-05-20 | 2019-02-01 | 中山市天图精细化工有限公司 | A kind of pearl powder aerosol |
| CN108524352A (en) * | 2018-04-19 | 2018-09-14 | 绍兴文理学院 | A kind of radioresistance preparation and its application |
| CN111096980A (en) * | 2020-01-16 | 2020-05-05 | 广州启初生物科技有限公司 | Preparation method of nano coral powder |
-
2001
- 2001-11-13 CN CNB011322136A patent/CN1165316C/en not_active Expired - Fee Related
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| CN1351869A (en) | 2002-06-05 |
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