CN1164339C

CN1164339C - A system related to intravenous anaesthesia

Info

Publication number: CN1164339C
Application number: CNB008157049A
Authority: CN
Inventors: J・G・杰克毕森; J·G·杰克毕森; A・斯道姆伯格; S·P·A·斯道姆伯格
Original assignee: Aneo AB
Current assignee: Aneo AB
Priority date: 1999-11-15
Filing date: 2000-11-13
Publication date: 2004-09-01
Anticipated expiration: 2020-11-13
Also published as: SE9904123D0; SE523272C2; CN1390144A; WO2001036026A1; AU1747301A; US6972009B1; EP1231959A1; JP2003513760A; SE9904123L

Abstract

The invention shows that conditions can be created in intravenous anaesthesia in which single-patient parts and accessories are separated from multi-patient parts and accessories by utilisation of a filter preventing contaminating particles from migrating from single-patient parts and accessories to multi-patient parts and accessories.

Description

The system relevant with intravenous anesthesia

The field of the invention

The present invention relates to the system in the intravenous anesthesia, and be particularly related to and be used for the system of intravenous anesthesia to dopey patient's adjustable delivery.

The present invention also is specifically related to a kind of system, and this system comprises at least one container that is used for described fluid medicine, is used to regulate time per unit to the circuit that described patient provides medication amount, reaches the pipe between described container and self patient.

Below use term " patient " in the explanation." patient " is meant and need treats the people and different animals who anaesthetizes for the surgery hands.

Prior art

Previously known injection nutritional support liquid, or with the venoclysis of the comparable liquid of injection nutritional support liquid, use to introduce venous conduit, syringe needle or sleeve pipe (intubate), and being connected of this sleeve pipe and the pipe between the container of the level that is higher than the patient of depositing described injection liquid such as saline solution etc.In these were used, container was suspended on the support usually.

Attached on pipe have a valving, by this valve, the regulated fluid amount can be set with the difference that produces different pipe chokings, i.e. the Fluid Volume of time per unit institute infusion.

Such device is relevant with the patient.This meaning is that relatively cheap container, pipe, valving etc. are abandoned after fluid infusion, and the accuracy of flow rate infusion does not have strict requirement.Fluid pressure in pipe and the sleeve pipe will depend on the height of fluid container on the patient.

Do not have very high requirement for spatter property because selecteedly be Fluid Volume whole in the container and only be used for a patient, and because empty and relevant valving and pipe thereof after transfusions such as injection nutritional support liquid, be abandoned.

Yet when relating to intravenous anesthesia, to the accuracy of medication infusion rate, the speed of setting is to the variation of time correlation, and conveying capacity and spatter property have higher requirement.

In field involved in the present invention is in the intravenous anesthesia, the medicine that causes anesthesia offers the patient from vein, usually big in the initial period amount, so that cause required patient's deep anaesthesia, after this provide medicine in a small amount so that keep in the suitable limit that the patient is in required depth of anesthesia.

The required medicine of this purposes is to provide in the container of the volume that maintains the standard, concentration etc.Also known condition based on the patient (age, sex, race, body weight etc.) corresponding to carrying out the required time of surgical intervention, is estimated required time of appropriate anaesthetization state and required anesthesia, and is selected the medicament reservoir volume.

It is very coarse that yet this estimation has proved, because each surgical intervention all is unique, and the persistent period is very difficult definite in advance.

What used time ratio was estimated if perform the operation lacks, then may the left too many left drug amount that will abandon in container and the pipe.If the length that the time ratio that operation continues is estimated then must be replaced empty medicament reservoir with new full container.

This during surgical intervention is very inconvenient situation with full container replacement empty, this is not only because the danger of wrong connection, therefore the common practice is the container that uses medication volume excessive at the very start, thereby has obviously increased the surplus when surgical intervention finishes.

If the capacity of selecting is still not enough, then exhausted empty must replace with full container.Experience shows that excess drug can cause the surplus that must abandon in the new container.

These containers are placed in the transfusion unit usually, wherein the defeated medication amount of time per unit are regulated, and this makes that replacing empty with full container is a time-consuming step.

With hypnotic and lethargy medicine venous transfusion and induced anesthesia the time, also use analgesic drug product and/or medicine of flaccid muscles usually.

Container, pipe etc. all will use design for independent patient.

It is very big that a plurality of patients of medicament reservoir use the danger that pollutes, because from first patient's antibacterial, viral and similar granule may be transferred in the medicine of container by pipe, and sends next patient to.

Contaminated so then medicine may offer the second, the three by same sleeve pipe and/or same container, the 4th patient etc.

Previously known some different systems and devices are used for anaesthetized adjustable infusion regulation and control by anesthesia patient's transfusion.Here use the transfusion unit pump that keeps normal pressure (syringe construction) in the container, force medicine to enter the patient by pipe and sleeve pipe.

This application has high requirements to the high scalable of time per unit medicine and the infusion of accuracy controlling, and the control of this process is had high requirements, and this control depends on the detectable condition relevant with the patient.

This simple embodiment of system that is used for intravenous anesthesia comprises that at least one is used to hold the container of described fluid medicine, a circuit that is used to regulate the medication amount that time per unit provides to the patient, and the pipe between a described container or described circuit and the described patient, the one end is connected on the sleeve pipe that inserts vein etc.

The container that has pipe and valving is formed a unit usually, and can be placed in the transfusion unit, wherein comprises by the pump that is connected to infusion unit's control unit control.

This known devices is illustrated in the following explanation embodiment illustrated in fig. 2 in sufficient detail.

Previously known has the using method of the transfusion unit of relevant control unit, wherein control unit is designed to based on relevant with the patient parameter with other, motion according to stepping motor, may command drives the stepping motor that is connected to syringe piston, so that regulate and medication amount that the estimation time per unit provides and the medicine total amount that provides.

Thereby design of the present invention mainly is to be used for the anesthesia process, especially for intravenous anesthesia.

So the present invention relates to and comprise a system, allow to carry out the transfusion of time per unit anesthetic agents Fluid Volume to live organism or patient's blood.

Here, in fact must use pulmonary respiration device and supervision and transfusion unit, wherein can be to the degree of depth of patient's induced anesthesia in the limit that the degree of depth of anesthesia is selected by the latter of control unit control.

Explanation of the present invention

Technical problem

If situation about relating to is, what those skilled in the art will consider in solving one or more technical problems is technical elements, and what then begin to see clearly is step and/or the order of step and the selection of required means that must take.Based on this, following technical problem should be a problem relevant in realizing the present invention.

Supervise in above-mentioned prior art, should use simple means to realize such condition, make wherein regardless of the narcotism persistent period, finish operation and intravenous anesthesia finish after remaining residual drug amount remain minimumly, this should be looked at as a technical problem.

Use simple means to realize such condition, making certain parts and adnexa can be designed to independent patient uses and is used for little residual quantity, and other parts and adnexa are designed to a plurality of patients' uses, and not having contamination particle to move to used parts of a plurality of patients and adnexa from independent patient used parts and adnexa, this is another technical problem.

Use simple means, parts that are used for a plurality of patients and adnexa and be used for independent patient's parts and adnexa between form separating surface (interface) different or that differentiate easily, and preventing that contamination particle from moving to the latter from the former, this also should be counted as a technical problem.

Here another technical problem is, uses simple means to realize such condition, makes at anestheticing period, particularly when anesthesia finishes, basically again the container of the emptying that is used for anaesthetic is filled in a small amount, so that keep low residual quantity.

Can understand the importance of in the present technique field, realizing this condition, make the connecting device press the flow direction installation and/or some other and/or some additional connecting device, can be designed at medicine during a direction proper flow, prevent that little contamination particle migration from entering described container, this is a technical problem.Described connecting device is arranged so that residual quantity is very little.

Can understand the importance that a large-rolume container is divided at least two parts, promptly a part be hold small quantities of drugs in the transfusion unit container (for example, syringe, pump etc.), and a part is as the storage capsule that holds high amount of drug, directly or indirectly be connected to described container, this is a technical problem.

Another technical problem is, can understand importance and advantage that the container that has the transfusion unit that is used for the adapter that medicine heavily annotates is provided.This adapter must be positioned near the container medicine outlet or by this medicine outlet and constitute.

Another technical problem is, can understand the importance and the advantage of carrying out following item, promptly design infusion unit's control unit, the feasible content that at first empties infusion unit container, contain anesthetic agents from storage capsule on a small quantity to described container transport then, thereby keep residual quantity very little.

A technical problem is to understand the importance of following item, promptly proposes for example to comprise the device of one-way cock between container and the storage capsule.

Another technical problem is to understand the importance and the advantage of following item, promptly among the connecting device or near the use simple means filter is set, prevent that contamination particle from passing a plurality of patient's used units and adnexa and the separating surface between patient's used unit and the adnexa separately.

Another technical problem is, uses simple means to realize such condition, though make it is not Continuous Flow by fluid or medicine, also can be continuously to patient's infused drug.

Another technical problem is the importance and the advantage that can understand following item, gives described filter equipment a kind of device that is used to close continuous drug flow.

Another technical problem is the importance and the advantage that can understand following item, a kind of filter of configuration between container and storage capsule, it is designed to prevent antibacterial, virus and similarly contamination particle arrive medicine in the storage capsule, be used for a plurality of different people or patient thereby make it possible to use medicine in the storage capsule to measure as a supplement.

Another technical problem is the importance and the advantage that can understand following item, configuration a kind of valve-off (choke valve) between storage capsule and connecting device.

Within the scope of the invention, selected container and/or storage capsule can be made of rigid container, or container and/or storage capsule can be made of flexible container.

A technical problem is, provides common device to described connecting device, is used for carrying medicine and carrying air to it from storage capsule, particularly when storage capsule is rigid container.

Another technical problem is the importance and the advantage that can understand following item, have dual channel filtered device or connecting device, promptly have a drug channel and an air duct of being separated from each other, a filter deployment that is used for stoping airborne thin, virus and other contamination particle is at air duct.

Another technical problem is the importance and the advantage that can understand following item, uses a container of transfusion unit, has first capacity corresponding to anesthesia starting stage desired volume, so that induce the patient to anaesthetize the required degree of depth.After the starting stage, transfusion unit is designed to provide every designing unit medicine in a small amount to the patient, so that keep the patient to be in the suitable limit of required anesthesia.

Another technical problem is the importance that can understand following item, use the three-dimensional adapter, be connected to container, storage capsule and patient's pipe, in the route that leads to storage capsule and pipe, use one-way cock, the one-way cock that is used for storage capsule be designed to just pressure surpass preliminary election greater than from the hydrostatic pressure value of storage capsule the time, just allow medicine to pass through.

Technical problem as related technology is considered and must be solved should be appreciated that and must dispose a filter in the upstream and/or the downstream of unidirectional filter, and/or a unidirectional filter can be configured in the upstream and/or the downstream of described filter.

A technical problem is to understand the importance and the advantage of following item, in conjunction with one-way cock and filter and they are arranged close to each other.A separating surface can also be configured between three-dimensional adapter and the one-way cock.Substitute as a kind of, described separating surface can be configured in the filter upstream, preferably near storage capsule.

A technical problem is to understand the importance and the advantage of following item, use an infusion unit container, its second capacity is less than first capacity, be designed to empty and fill again the initial required patient's depth of anesthesia of inducing by what described second capacity is selected number of times, transfusion unit is designed in initial period time per unit conveying afterwards than a small amount of medicine, so that keep the patient to be in the suitable limit of required depth of anesthesia.

A technical problem is to understand the importance and the advantage of following item, and pipe is connected to filter, and is provided with separating surface in the upstream and/or the upstream of described filter.

A technical problem is to understand the importance and the advantage of following item, regulating circuit (circuit) for example is included in the piston cylinder apparatus that any side has one-way cock, the reciprocating motion of piston is controlled by the control circuit in the transfusion unit, thereby thereby provide a chance that described piston cylinder apparatus and described one-way cock are combined in the single unit, this unitary profile is designed to the shape of the depression of adaptive infusion unit container, a filter installment is in described unitary upstream and/or downstream, and described separating surface is located at the downstream and/or the upstream of described filter.

A technical problem is to understand the importance and the advantage of following item, is having between jumbo container and the sleeve pipe etc. by one or more filters and medicament adjusting circuit (path) configuration pipe.

A technical problem is to understand the importance and the advantage of following item, design described circuit, make and utilize dull and stereotyped or similar control unit peripheral components blocking-up and/or open pipe section that so that regulate the supply of medicine, described filter configuration is in the downstream and/or the upstream of described circuit.

A technical problem is to understand the importance and the advantage of following item, design medicine regulating circuit, so that only based on the supply of the condition control medicine relevant with the patient, the container that the supply of medicine is arranged on patient's level provides.

A technical problem is to understand the importance and the advantage of following item, designs described circuit, makes to block and/or open pipe section by means of pump or the similar peripheral components of control unit, so that regulate the supply of medicine.At this moment one or more filters can be configured in the downstream and/or the upstream of described pumping unit, and separating surface is located at the downstream and/or the upstream of a filter.

Solution

The present invention is based on a system, this system is suitable in intravenous anesthesia dopey patient being carried out the infusion of fluid medicine, described system comprises that at least one holds the container of described fluid medicine, be used to regulate the circuit that time per unit flows to described patient's medication amount, and at described circuit and/or container to the pipe between the described patient, a connecting device is installed between described container and the described pipe, and is configured to make medicine to flow to the patient from described circuit and/or container by described pipe.

In order to solve one or more above-mentioned technical problems, the present invention shows that connecting device can be made up of a filter, it is designed to a plurality of patient's used units and adnexa are separated with independent patient's used unit and adnexa, and described filter forms a separating surface, prevents that contamination particle from moving to the former parts and adnexa.

Further refinement as the present invention's design, be configured in connecting device of flow direction and/or another and/or some additional connecting device, be designed at medicine during a direction proper flow, prevent that little contamination particle from passing through to described container, and connecting device is configured to keep residual quantity very little.

Use the system of the above-mentioned type, as the idea of further exploitation, the present invention also proposes container is divided into two parts at least, and promptly a part is the container in the transfusion unit, and another part is the storage capsule that is connected with described container.

In addition, the present invention shows that infusion unit container has medicine filter adapter, is positioned near the outlet or by medicine outlet to constitute.

In addition, the present invention shows that infusion unit's control unit is designed like this and can control like this, makes it at first empty the content of infusion unit container, carries a spot of medicine from storage capsule then one by one, thereby keeps little residual quantity.

The present invention shows that also the valving of being made up of at least one one-way cock is arranged between container and the storage capsule.

In addition, the present invention shows, described filter deployment between container and storage capsule, be designed to stop antibacterial, virus and similarly contamination particle move in the medicine that is contained in the storage capsule.

A valve can also be configured between storage capsule and the connecting device.

This storage capsule and/or this container can be made up of rigid container (bottle), or preferably are made up of flexible container (bag).Use rigid container, described connecting device must have the device that sends air to storage capsule.

This shows that connecting device must have two parts, i.e. a passage and passage that is used for air that is used for medicine, and antibacterial, virus and similar contamination particle that filter deployment is propagated with blocks air in air duct pass through.

The present invention proposes, and infusion unit container should have first capacity, and it is corresponding in order to induce the needed medication amount of desirable depth of anesthesia during initial period.

Transfusion unit is designed to provide time per unit medicine in a small amount to the patient after initial period, so that keep the patient to be in the suitable limit of required depth of anesthesia, and realizes little residual quantity.

One three path connector is connected to container, storage capsule and patient's pipe, and one-way cock is configured on the route of storage capsule and pipe.

The one-way cock of storage capsule is designed to, and only surpasses predetermined value at pressure, during promptly a little higher than hydrostatic pressure from storage capsule, just allows medicine to pass through.

A filter preferably can be configured in the upstream of described one-way cock, and one-way cock preferably can be configured in the upstream of described filter.

Close (damming) and/or open (opening stream) valve for one and can be configured in the upstream of described one-way cock.

An one-way cock can be connected with a filter close to each otherly.

Here, described separating surface can be configured between three path connectors and the one-way cock.

Thereby described separating surface can be configured in the upstream of filter, and/or this separating surface can be configured near the storage capsule.

The container of transfusion unit can have second capacity less than described first capacity, is designed to during initial period, described second capacity is emptied and filled again number of times initial anesthesia of inducing desired depth with what select.

Transfusion unit is designed to provide time per unit medicine in a small amount to the patient after initial period, so that keep the patient to be in the suitable limit of required depth of anesthesia.

Here, pipe can be connected to filter, and separating surface can be configured in the downstream and/or the upstream of described filter.

Regulating circuit can be made up of piston cylinder apparatus that has one-way cock in any side etc., and the reciprocating motion of piston is controlled by the control circuit in transfusion unit.

Described piston cylinder apparatus and described one-way cock are combined into a physical location, can make its profile accurately adapt to the depression (dimple) of the transfusion unit that aims at Vessel Design.

The present invention shows that also a filter deployment is in described unitary upstream, and described separating surface is configured in the downstream and/or the upstream of described filter.

Pipe is configurable between jumbo container and sleeve pipe etc., and it is by one or more filters, and the medicament adjusting circuit.

Here, described circuit is designed to, and by the effect to (periphery) around the pipe such as control unit plate, the cross section of blocking and/or opening pipe is so that regulate the supply of medicine.

Described filter deployment is in the downstream and/or the upstream of described circuit, and described separating surface can be configured in the downstream and/or the upstream of described filter.

Based on the supply of the condition control medicine relevant with the patient, the supply of medicine preferably is arranged to from the supply for receptacles more than patient's level the medicament adjusting circuit design for only.

Described circuit also is designed to, by pump or the control unit cross section that effect is on every side blocked and/or opened pipe to pipe, so that regulate the supply of medicine.

Here, the present invention proposes downstream and/or the upstream of one or more filter deployment at described pumping unit.

Described then separating surface can be configured in the downstream and/or the upstream of one or more filters.

The medicament adjusting circuit can also be configured to, based on the supply of control medicine such as the medication amount of patient's correlated condition, supply, though just consider the medication amount supplied with about time per unit or total information for dose.

Even here, the supply of medicine also can be designed to carry out from the container more than patient's height.

Advantage

Major advantage according to system of the present invention is, use simple means to realize such condition, by using connecting device that some parts is become with attachment design for a plurality of patients to use, and with other parts and attachment design for for independent patient's use, connecting device is preferably the form of the filter between them, used parts and the attachment design of patient is used for little residual quantity separately, wants the undesirable residual quantity of abandoned anesthetic agents thereby limited.

In fact this is to use infusion unit container to realize, its drug capacity is designed to equal or is slightly smaller than to realizing suitable persistent period of anesthesia, required depth of anesthesia and the required amount of other correlated condition.More if desired medicine can provide small quantities of drugs one by one from storage capsule, thereby is formed for keeping anaesthetizing the condition of little residual quantity when finishing.

This has reduced the medication amount that will remove and abandon usually, because the common unitary capacity of medication infusion of reason of safety is overdimensioned greatly.Connecting device and filter have prevented the medicine that pollutes simultaneously, move to the medicine that uses for one or more other patients from a patient.

Proposed the main inner characteristic in the system in the characteristic of Patent right requirement 1, this system is used for regulating provides fluid medicine to the patient, and patient's anesthesia is inductive by intravenous anesthesia.

Brief description of drawings

Now with reference to accompanying drawing the system that is used for fluid and medicine venoclysis of two previously knowns is described in more detail, and a kind of system of proposing of the present invention, wherein:

Fig. 1 illustrates and is used for from the principle of container to the venoclysis of patient's intravenous injection nutritional support liquid, and wherein fluid can be made up of for example saline solution;

Fig. 2 illustrates the critical piece of transfusion system, is used for carrying out adjustable infusion of drug to the people who does intravenous anesthesia;

Fig. 3 illustrates the principle according to the first embodiment of the present invention;

Fig. 4 illustrates the longitudinal profile of the connecting device of the filter that has drug channel and air duct that is proposed;

Fig. 5 illustrates principle according to a second embodiment of the present invention;

Fig. 6 illustrates the principle of a third embodiment in accordance with the invention;

Fig. 7 illustrates the principle of a fourth embodiment in accordance with the invention;

Fig. 8 illustrates principle according to a fifth embodiment of the invention;

Fig. 9 is a sequential chart, the variation of the medication amount of expression anestheticing period institute infusion.

The explanation of prior art

Fig. 1 is the diagram of a system, and this system is used for adjustable limit of intravenous injection nutritional support liquid Precision adjustment processed is such as the venoclysis salting liquid that is used for to the people.

Fig. 1 illustrates the sleeve pipe 1 of the vein 2 that is inserted in the arm 3.

Sleeve pipe 1 is connected to pipe 4, and one end 4a is connected to described sleeve pipe 1, and other end 4b connects To container 5, contain fluid 6 flexible plastic container of salting liquid for example normally.

Here, a valving 7 be attached in or be configured in pipe 4 around, and can pass through valve The Fluid Volume of time per unit institute infusion is regulated in device 7 effect in the known manner.

Should be noted that the fluid infusion to this application does not need very high accuracy. So, when whenever When the Fluid Volume of unit interval institute's infusion is not strict, can use simple valving 7.

In addition, the big flow under some situation for example arrives greatly 500ml/ hour or higher, can with This valving provides.

The fluid medicine amount that is used for regulating dopey patient's infusion requires higher accuracy.

The necessary a large amount of fluids of initial infusion of this process, and greatly reduce then the adjustable water of flow to Flat, thus realize required depth of anesthesia. This as shown in Figure 9.

Fig. 2 is the schematic diagram of syringe 11 in the transfusion unit 10, reaches with container 12, piston 13 The control module 14 that comprises stepping motor 15.

Comprise at least one container 12 for contain fluids medicine 16 according to this system of Fig. 2, with And regulating circuit or control module 14, be used for regulating failing to described personnel's time per unit medication amount Annotate.

In addition, pipe 4 is configured between described container 12 and the described patient P.

Be configured in the jockey 17 between described container 12 and the described pipe 4, be arranged to make medicine 16 can flow to patient P by described control module 14 and described pipe 4 from described container 12.

Fig. 2 represents, the device that an end 4a of pipe is connected to three path connectors or is equal to, so that One or more containers 11,11 ' can be connected to pipe 4 ', and the one end is configured to connect with sleeve pipe 1 Connect.

The explanation of the embodiment that is proposed

The present invention is based on such experience, promptly the user usually selects the medicine 16 of the capacity more much bigger than anestheticing period consumption, avoiding and need empty syringe be renewed at intra-operative, or fills empty syringe again with medicine.

So remaining down big residual quantity, and because the danger of infecting and can not keeping for other patient's use.

The present invention is based on a kind of system, be used for during intravenous anesthesia regulating adaptive to the medicine of patient's infusion of accepting anesthesia, described system comprises that at least one holds the container of described fluid medicine, be used to regulate the regulating circuit or the control unit of the medication amount of time per unit infusion, and the pipe between described circuit or container and described patient, be equiped with a connecting device, it is arranged to allow medicine to lead to the patient from described container.

A filter of linking connecting device is designed to and will separates with the parts and the adnexa that use for independent patient for the parts and the adnexa of a plurality of patients' uses.This filter forms one and prevents that contamination particle from moving to the separating surface of the former parts and adnexa.

In other words, the amount of medicine 16 can be less and wide nargin arranged than being used for the necessary amount of calculation of induced anesthesia, and the medication amount of replenishing can transmit to syringe 11 from storage capsule 11a.

Container 11a and storage capsule 11b interact by connecting device 31, this connecting device can comprise valve (V1, V2) and filter (F1).

Described connecting device 31 and/or some other and/or some additional connecting device that has filter that is configured in flow direction, be designed to pass through pipe 4 during the assigned direction proper flow, prevent that little contamination particle is to described container 11b and/or container 11a migration at medicine.The configuration of connecting device has guaranteed that residual quantity is very little.

Fig. 3 illustrates container 11 and is divided at least two part 11a, 11b, and one is container or the syringe 11a that holds selected small amount of drug in transfusion unit 10, one is the storage capsule 11b that holds high amount of drug that is connected with described container 11a.

Here, the medication amount of container 11a can be selected at the reason outside the surgical intervention persistent period of estimating, and can be much smaller, because available competent storage capacity is arranged in storage capsule 11b.

The present invention proposes to use one or more filter F, and this/these filters the used parts of a plurality of patients and adnexa A and single patient used parts and accessories B separate.

Filter F forms a separating surface C, has prevented that contamination particle from moving to the used components A of a plurality of patients from the used part B of single patient.

Parts that single patient is used and accessories B are designed to have little residual quantity when anesthesia finishes.In other words, at this moment container 11a should come down to sky.Other parts and adnexa are selected for little residual quantity.

Fig. 3 is the sketch map that has first embodiment of feature related to the present invention.

The container 11a of transfusion unit 10 has adapter 11b ', can fill medicine by this adapter, and this adapter is configured near the medicine outlet 11a ' or is made up of this outlet.

The control unit 14 of transfusion unit 10 can be designed to make the content of infusion unit container 11a to empty, and carries a spot of anesthetic agents that contains from storage capsule 11b as required then one by one, so that keep the little residual quantity in the used parts of single patient.

This can work as piston 13 and realizes when moving back and forth in dotted line scope shown in Figure 3, so as medicine from container 11b pump to container 11a, and deliver to the patient by three path connectors 31 and pipe 4 from container 11a.

Can finish anesthesia with little residual quantity now, because container 11a is empty, and pipe section is little.

Several valvings V is configured between container 11a and the storage capsule 11b, and each comprises an one-way cock these valvings.

First one-way cock V1 packs into or connects near 31, the second one-way cock V2 of described three path connectors and packs into or near the path of described three path connectors 31 to storage capsule 11b.

One-way cock V2 is connected to first filter F 1.

Another way is that filter F 2 can be connected near storage capsule 11B with one-way cock V3.

Can omit filter F 1 and one-way cock V2 in some applications.At this moment selected separating surface is moved to the position that is labeled as C1.

Filter F 1 and/or filter F 2 are designed to stop that antibacterial, virus and similar contamination particle enter the medicine 16a among the storage capsule 11b.

Storage capsule 11b and/or container 11a preferably can be flexible or inflexible container.

When adopting rigid container 11b, propose a kind of device and be used for when storage capsule 11b empties medicine 16a, to storage capsule 11b air supply.

For being provided, a medicine outlet and an air intlet do not have any obstruction.

Fig. 4 illustrates this class composite set can be divided into two parts, and promptly passage 43 is used for medicine and passage 44 is used for air, filter 45 be configured in the air duct with prevent antibacterial, virus and similarly contamination particle enter container 11b from ambient air.

Drug channel 43 has the upper space 43a that fills with medicine 16a.This medicine is by filter element 43b and by drip nozzle 43c, and its Chinese medicine drops in by before some additional filtering device F3 or the valve, pass inflation (filling air) space 43d and arrive space 43e.

Fig. 3 also illustrates the use of the container 11a of having of transfusion unit 10 of first capacity 11a, its objective is at initial period to be used for the required depth of anesthesia of rapid induction.

Transfusion unit also is designed to, and time per unit medicine in a small amount is provided after initial period, so that keep the patient to be in the suitable limit of required depth of anesthesia.

Here should be noted in the discussion above that for initial period t0 to the hypnosis dose that infusion proposed of t1 at 3 to 4 minutes infusions 10 to 30ml, for example infusion 20ml in 2 minutes.In the quantity delivered of all the other time t1 during the t2 can be 50 to 100ml/ hour.The total amount of anestheticing period infusion can be 100 to 500ml.

Be noted here that can be 1 to 2ml for initial period t0 to the pain relieving dose that infusion proposed of t1.All the other time durations infusion amount can be 10 to 50ml/ hour.

Be noted here that can be 3 to 5ml for initial period t0 to the dose of flaccid muscles that infusion proposed of t1.The infusion amount of all the other time durations can be 3 to 5ml/ hour.

Should be noted that above-mentioned each medicament needs independent transfusion unit and control unit.

Somnifacient is infusion one by one preferably, and long-acting analgesic is infusion one by one preferably also, and muscle relaxant can be under controlled condition continuous infusion.

Three path connectors 31 are connected to container 11a by the one-way cock in the pipeline that leads to storage capsule 11b and pipe 4, storage capsule 11b and patient's pipe 4.One or more filters three path connectors 31 of can packing into.

The one-way cock (V2) that is used for storage capsule 11b is designed to, and just when pressure surpasses the preset value of a little higher than hydrostatic pressure from storage capsule 11b, just allows medicine 16a to pass through.

Filter F 1 is configured in the upstream of described one-way cock V2, and additional one-way cock V3 is configured in the upstream of described filter F 1.

Close and/or open the valve (not shown) and can be configured in the upstream of described one-way cock V3.

One-way cock V2 (V3) and filter F 1 (F2) be close to each other interconnecting and form a unit preferably, separating surface C preferably is located between three path connectors 31 and the one-way cock V2, but also separating surface might as well be located near the upstream and/or storage capsule 11b of filter F 1.

Fig. 5 illustrates the replacement form of Fig. 3, wherein the container 11a ' of transfusion unit 10 has the second capacity E2, it is more much smaller than the first capacity E1, and the former is designed to empty and fill the described second capacity E2 at initial period with the number of times of selecting, so that the patient to be provided required depth of anesthesia.

Proposition with capacity E2 be chosen to need carry out emptying for 2-5 time at initial period, so that the medicine of q.s to be provided.

Transfusion unit also is designed to, and after initial period, provides time per unit medicine in a small amount to the patient, so that keep the patient to be in the suitable limit of required depth of anesthesia.

Fig. 6 illustrates another embodiment, and wherein container 11a removes, and medicine only provides from a bulk container 11b.

Here, pipe 4 is connected to filter F 4 and/or F5, and one or more separating surface C2, C3, and C4, C5 can be configured in the downstream and/or the upstream of described filter.

Here, regulating circuit or control unit 14 are made up of piston cylinder apparatus 61, and each side has an one-way cock V4, V5, and the reciprocating motion of piston is by 14 controls of the control circuit in the transfusion unit.

Described piston cylinder apparatus 61 and described one-way cock V4, V5 is combined into one unit 62, and its profile adapts to the shape of the transfusion unit depression that is designed to fixed container 11a.

The upstream that makes filter F 4 be configured in described unit 62 may be important.

Described separating surface C2, C3 are configured in the downstream and/or the upstream of described filter F 4.

Embodiment according to Fig. 7 expresses, and one pipe 4 is configured between large-rolume container 11b and the sleeve pipe etc., passes through one or more filter F 6 and F7 respectively, and medicament adjusting circuit 71.

Described circuit 71 is designed to, and by means of the stepping motor 15 of plate 71a etc., stopper 71b and control unit 14, blocks and/or open pipe section, so that regulate the supply of medicine.

Described filter F 6, F7 is configured in the downstream and/or the upstream of described circuit, one or more separating surface C6, C7, C8, C9 are configured in described filter F 6, the downstream of F7 and/or upstream.

Medicament adjusting circuit or control circuit 14 are designed to, and only control the conveying of medicine based on the condition relevant with the patient.The dose of being carried and/or the amount of time per unit can be estimated that so that provide Useful Information to the surgeon, but this is not the part of control procedure.This tittle can obtain from the setting that control unit reaches stepping motor.

The condition relevant with the patient reaches can be by carrying out with described mode shown in the following Swedish patent application to its selection, this patent application is 9901688-3, May 10 in 1999 submitted to, and name is called " Arrangemang for att kunna tilldela en levande varelse ettanestesialt tillstand " (promptly inducing the narcose device of living body biological).

The content of described patent application will be regarded as the application's a part.

Here, the infusion of the medicine container 1b that will be designed on patient's level carries out.

Fig. 8 illustrates control unit 14 and causes the medicament adjusting circuit 14 that has stepping motor 15, so that by means of the similar unit 81 around pump (forcing fluid or medicine flow further downstream) or the pipe with wriggling, blocking-up and/or the cross section of opening pipe 4 are so that regulate the conveying of medicine.Here dispose telecontrol equipment 81a, it acts on fixing head 81b.

Filter F 8, F9 is configured in the downstream and/or the upstream of described pumping unit 81, and described separating surface C10, C11, C12, C13 can be configured in downstream and/or the upstream of filter F 8 and F9 respectively.

Configuration medicament adjusting circuit is the information that the instantaneous medication amount that provides according to the condition relevant with the patient with from time per unit is provided, and regulates the conveying of medicine.

Fig. 9 illustrates with solid line, provides bigger dose at initial period t0 to t1, so that the rapid induction patient enters narcotism.Required depth of anesthesia is represented by dotted lines.

Provide a less regulated quantity of anesthetic agents for the of short duration interval of t1-t2,, or be used for the in check adjusting of depth of anesthesia so that keep the patient to be in required depth of anesthesia.

Using value for patient's condition to be used to regulate interval from t1 to t2, providing the probability of medicine, also belonging in the scope of the present invention with a kind of amount and with the speed that conforms to empirical value.

" one by one " infusion meaning of medicine or medicament is meant with given amount (1/2) and fills empty (11a) again.This amount is cleared and fills less magnitude (1/4) etc. then again.

Obviously the invention is not restricted to above exemplary embodiment, but can in the concept and range of the present invention described in the following Patent right requirement, make amendment.

Claims

1. be used for controllably regulating to will be with the system of the infusion of the dopey one or more patients' of venous transfusion fluid medicine, described system comprises that at least one holds the container of described fluid medicine (11a), be used to regulate the circuit (14) that time per unit flows to described patient's medication amount, and at described circuit (14) or container (11a) to the pipe between the described patient, be provided with the permission medicine leads to described patient from described container (11a) connecting device (31) at this, it is characterized in that, described connecting device (31) is for being suitable for comprising the form of a filter (F1), described connecting device (31) is designed to the used parts (11b one or more patients, F2, V3) and adnexa, comprise hold with described container (11a) in second container (11b) that uses as complementary tank of identical fluid medicine, the parts (14 used with independent patient, 11a) and adnexa, described first container (11a) that comprises the contain fluids medicine, separately, and described filter (F1) is designed to form a separating surface, prevents that contamination particle is by moving to the former parts (11a) and adnexa to the venous transfusion of one or more sequences of wanting dopey patient.

2. according to the system of claim 1, it is characterized in that, be configured in the described connecting device of flow direction, and/or certain other and/or certain additional connecting device, be designed at medicine during a direction proper flow, prevent that little contamination particle from moving to described container, and described connecting device is configured to the residual quantity that keeps little.

3. according to the system of claim 2, it is characterized in that this container is divided into two parts at least, i.e. container in transfusion unit, and one be connected or adjacent storage capsule with described container.

4. according to the system of claim 2 or 3, it is characterized in that this infusion unit container has a connector, this adapter is configured to form near medicine outlet or by medicine outlet, and medicine fills by it.

5. according to the system of claim 3, it is characterized in that a control unit in the transfusion unit is designed to, and empties the content of infusion unit container, carries a small amount of anesthetic agents from storage capsule then, so that keep little residual quantity.

6. according to the system of claim 3, it is characterized in that, comprise that the valving of at least one one-way cock is configured between this container and this storage capsule.

7. according to any one system among the claim 1-3, it is characterized in that, described filter deployment between this container and this storage capsule, be designed to prevent antibacterial, virus and similarly contamination particle arrive medicine in this storage capsule.

8. according to the system of claim 2, it is characterized in that a valve configurations is between this storage capsule and this connecting device.

9. according to the system of claim 2 or 3, it is characterized in that this storage capsule is a rigid container.

10. according to the system of claim 2 or 3, it is characterized in that storage capsule is a flexible container.

11. the system according to claim 9 is characterized in that, described connecting device has device from air to this storage capsule that carry.

12. system according to claim 9, it is characterized in that this connecting device is divided into two parts, i.e. a drug channel and an air duct, a filter deployment is in air duct, and the antibacterial, virus and the similar contamination particle that are designed to the blocks air propagation pass through.

13. the system according to claim 1 is characterized in that, a container of transfusion unit has first capacity, this first Capacity Selection for corresponding to during initial period for inducing the patient to reach the needed medication amount of desirable depth of anesthesia.

14. the system according to claim 13 is characterized in that, this transfusion unit is designed to, and after initial period, time per unit provides medicine in a small amount, so that keep the patient to be in the suitable limit of required depth of anesthesia.

15. the system according to claim 13 is characterized in that, one three path connector is connected to this container, this storage capsule and patient's pipe, and an one-way cock is configured on the route that leads to this storage capsule and this pipe.

16. the system according to claim 15 is characterized in that, an one-way cock of storage capsule is designed to, and only surpasses preset value at pressure, during promptly a little higher than hydrostatic pressure from this storage capsule, just allows medicine to pass through.

17. the system according to claim 1 or 16 is characterized in that, filter deployment is in the upstream of an one-way cock.

18. the system according to claim 1 or 16 is characterized in that, an one-way cock is configured in the upstream of described filter.

19. the system according to claim 18 is characterized in that, a upstream of closing and/or opening the described one-way cock of valve configurations.

20. the system according to claim 1 or 15 is characterized in that, an one-way cock and a filter combine and/or are arranged close to each other.

21. the system according to claim 1 or 15 is characterized in that, described separating surface is configured between this three path connector and this one-way cock.

22. the system according to claim 1 or 15 is characterized in that, described separating surface is configured in the upstream of this filter.

23. the system according to claim 1 or 15 is characterized in that, described separating surface is configured near this storage capsule.

24. system according to claim 1, it is characterized in that, a container of transfusion unit has second capacity less than described first capacity, be used for the initial patient of inducing and anaesthetize the required degree of depth, by during initial period to described second capacity select number of times empty and fill, anaesthetize the required degree of depth to induce the patient.

25. the system according to claim 24 is characterized in that, this transfusion unit is designed to provide time per unit medicine in a small amount to the patient after initial period, so that keep the patient to be in the suitable limit of required depth of anesthesia.

26. the system according to claim 1 is characterized in that, this pipe is connected to this filter, and this separating surface is configured in the downstream and/or the upstream of described filter.

27. the system according to claim 1 or 26 is characterized in that, regulating circuit for example is included in the piston cylinder apparatus that each side has one-way cock, and the reciprocating motion of piston is by a control circuit control in transfusion unit.

28. the system according to claim 27 is characterized in that, described piston cylinder apparatus and described one-way cock are combined into a unit, and its profile adapts to the shape into a depression of the transfusion unit of Vessel Design.

29. the system according to claim 27 is characterized in that, a filter deployment is in described unitary upstream and/or downstream.

30. the system according to claim 29 is characterized in that, described separating surface is configured in the upstream and/or the downstream of described filter.

31. the system according to claim 1 is characterized in that, this pipe is configured between a jumbo container and the sleeve pipe etc., by one or more filters and a medicament adjusting circuit.

32. the system according to claim 31 is characterized in that, described circuit is designed to, and the cross section that makes the control unit blocking-up and/or open pipe by plate etc. is so that regulate the infusion of medicine.

33. the system according to claim 31 is characterized in that, described filter deployment is in the downstream and/or the upstream of described circuit.

34. the system according to claim 1 or 33 is characterized in that, described separating surface is configured in the downstream and/or the upstream of described filter.

35. the system according to claim 31 is characterized in that, this medicament adjusting circuit design is for only controlling the supply of medicine based on the condition relevant with the patient.

36. the system according to claim 32 is characterized in that, the infusion of medicine is arranged to from the container more than patient's level and carries out.

37. the system according to claim 31 is characterized in that, described circuit design is, by the similar device cross section that makes the control unit blocking-up and/or open pipe around pump or the pipe, so that the infusion of adjusting medicine.

38. the system according to claim 37 is characterized in that, one or more filter deployment are in unitary downstream of described pump and/or upstream.

39. the system according to claim 37 is characterized in that, a separating surface is configured in the downstream and/or the upstream of a filter.

40. the system according to claim 37 is characterized in that, a medicament adjusting circuit is configured to, based on the condition relevant with the patient, and the information of the medication amount of supplying with based on time per unit for example, the infusion of control medicine.

41. the system according to claim 37 is characterized in that, the infusion of medicine is arranged to carry out from the container that is positioned at more than patient's level.