CN116413463A - Cup discarding mechanism of incubation unit, sample analyzer and cup discarding method - Google Patents

Cup discarding mechanism of incubation unit, sample analyzer and cup discarding method Download PDF

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Publication number
CN116413463A
CN116413463A CN202111672412.6A CN202111672412A CN116413463A CN 116413463 A CN116413463 A CN 116413463A CN 202111672412 A CN202111672412 A CN 202111672412A CN 116413463 A CN116413463 A CN 116413463A
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Prior art keywords
cup
reaction container
discarding
pushing
channel
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Chinese (zh)
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肖擎国
练子富
李临
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Kemei Boyang Diagnostic Technology Shanghai Co ltd
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Kemei Boyang Diagnostic Technology Shanghai Co ltd
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Priority to CN202111672412.6A priority Critical patent/CN116413463A/en
Publication of CN116413463A publication Critical patent/CN116413463A/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0444—Rotary sample carriers, i.e. carousels for cuvettes or reaction vessels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/046—General conveyor features
    • G01N2035/0465—Loading or unloading the conveyor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0482—Transmission
    • G01N2035/0487—Helix or lead screw

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The application relates to a cup discarding mechanism of an incubation unit, a sample analyzer and a cup discarding method. The incubation unit includes body and swing joint's branch annotates the dish, divide annotating the dish and be used for placing reaction vessel, divide annotate the dish relatively the motion of body can drive reaction vessel moves to abandoning the cup station, abandon the cup station setting abandon the cup mechanism, abandon the cup mechanism and include: the driving part can drive the pushing part to move when the reaction container moves to the cup discarding station, and the pushing part is used for separating and pushing the reaction container from the dispensing disc to a preset position; and a position detecting unit for detecting at least a position of the reaction vessel which moves after being separated from the dispensing tray. According to the scheme, when the throwing cup can be used for working, the reaction container can be ensured to move in place, and blockage is avoided.

Description

Cup discarding mechanism of incubation unit, sample analyzer and cup discarding method
Technical Field
The application relates to the technical field of medical instruments, in particular to a cup discarding mechanism of an incubation unit, a sample analyzer and a cup discarding method.
Background
A sample analyzer (biochemical analysis, immunoassay) is an instrument for detecting a specific substance in blood. In order to obtain a detection signal, the liquid in the cuvette is usually subjected to a specific reaction, such as a biochemical reaction, an immunological reaction. Such reactions generally need to be carried out under defined temperature conditions. If the reaction temperature does not meet the prescribed temperature, the reaction does not proceed sufficiently and a correct detection signal cannot be obtained. The incubation unit is an important component of the sample analyzer, is used for providing proper temperature for the reaction container, and needs to meet the procedures of sample injection, liquid adding, detection, unloading and the like, and for the incubation unit, the conversion and performance among the procedures have great influence on the accuracy and precision of the detection result.
Disclosure of Invention
In order to solve or partially solve the problems in the related art, the application provides a cup discarding mechanism, a sample analyzer and a cup discarding method of an incubation unit, which can ensure that a reaction container can move in place while realizing cup discarding work, and avoid blockage.
The first aspect of the application provides a abandon cup mechanism of incubation unit, incubation unit includes body and swing joint's minute notes dish, minute notes dish is used for placing reaction vessel, minute notes dish is relative the motion of body can drive reaction vessel moves to abandoning the cup station, abandon the cup station setting abandon cup mechanism, abandon the cup mechanism and include:
the driving part can drive the pushing part to move when the reaction container moves to the cup discarding station, and the pushing part is used for separating and pushing the reaction container from the dispensing disc to a preset position;
and a position detecting unit for detecting at least a position of the reaction vessel which moves after being separated from the dispensing tray.
A second aspect of the present application provides a sample analyzer comprising a cup discarding mechanism as described in the foregoing.
The third aspect of the present application provides a cup discarding method for incubating the unit, it includes the dispensing tray and places the reaction vessel on it and set up in the cup discarding mechanism of discarding the cup station to incubate the unit, it includes complex drive portion and pushing part and position detection subassembly to discard the cup mechanism, it includes to discard the cup method:
when the fact that the dispensing disc drives the reaction container to move to the cup discarding station is detected, the driving part is controlled to drive the pushing part to move, so that the reaction container is separated from the dispensing disc and pushed to a preset position, and in the process of pushing the reaction container to the preset position, if the reaction container detected by the position detecting component meets preset conditions, the reaction container is judged to be in a normal movement state in the cup discarding mechanism.
The technical scheme that this application provided can include following beneficial effect: through the matched driving part and the pushing part, the reaction container can be conveniently and rapidly separated from the dispensing disc and pushed to a preset position, and the reaction container pushed to the preset position can directly or indirectly enter the collecting device to finish the cup throwing work. The driving part directly controls the structure of the movement of the pushing part, is simple in cooperation and easy to realize, can ensure that the reaction container is accurately pushed to a preset position, and improves the stability and the precision of the throwing cup. Meanwhile, in the process that the driving part drives the pushing part to move, the position detection assembly is matched, at least the state that the reaction container moves in the cup throwing process can be detected, the cup throwing precision is further guaranteed, and the phenomenon that the pushing part does not drive the reaction container to a preset position at a certain time in the cup throwing process to cause the reaction container to be blocked in the cup throwing mechanism to influence the subsequent cup throwing work is avoided. The staff can in time clear up the reaction vessel that blocks up in abandoning cup mechanism according to the condition of reaction vessel motion position that the position detection subassembly detected, avoids seriously piling up the damage of reaction cup down and influencing the going on of follow-up throwing cup work.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application.
Drawings
The foregoing and other objects, features and advantages of the application will be apparent from the following more particular descriptions of exemplary embodiments of the application as illustrated in the accompanying drawings wherein like reference numbers generally represent like parts throughout the exemplary embodiments of the application.
Fig. 1 is a schematic structural view of a cup discarding mechanism disposed in an incubation unit according to an embodiment of the present disclosure;
FIG. 2 is a cross-sectional view of the embodiment of the present application showing the cup discarding mechanism mated with the body cup discarding station;
FIG. 3 is a schematic view of the structure of the cup discarding mechanism according to the embodiment of the present application;
FIG. 4 is a schematic cross-sectional view of a cup discarding mechanism according to one embodiment of the present disclosure;
fig. 5 is a schematic cross-sectional view of another cup discarding mechanism according to the embodiment of the present application.
Detailed Description
Embodiments of the present application will be described in more detail below with reference to the accompanying drawings. While embodiments of the present application are shown in the drawings, it should be understood that the present application may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.
The terminology used in the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the present application. As used in this application and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any or all possible combinations of one or more of the associated listed items.
It should be understood that although the terms "first," "second," "third," etc. may be used herein to describe various information, these information should not be limited by these terms. These terms are only used to distinguish one type of information from another. For example, a first message may also be referred to as a second message, and similarly, a second message may also be referred to as a first message, without departing from the scope of the present application. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present application, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
A sample analyzer (e.g., biochemical analysis, immunoassay) is an instrument for detecting a specific substance in blood. The incubation unit is an important component of the sample analyzer for providing the reaction vessel with a suitable temperature to meet the incubation requirements. In addition, in the incubation process, operations such as sample injection, sample adding and mixing, detection, unloading and the like are required to be performed on the sample.
Referring to fig. 1, the present application provides a cup discarding mechanism, and a cup discarding mechanism 2 is disposed at a cup discarding station in an incubation unit. The incubation unit includes body 1, and body 1 includes at least advances a cup station, application of sample mixing station, detects the station and abandons a cup station, divides annotate 3 swing joint in body 1 for place reaction vessel 4, and divide the action of annotating 3 to drive reaction vessel 4 and move to different stations. The stations operated differently in the incubation process are integrated in the body 1, and the action of the drive dispensing disc 3 can enable the reaction container 4 to be conveniently and stably converted into the corresponding station.
The cup discarding mechanism 2 comprises a driving part 21, a pushing part 23 and a position detecting assembly 22, wherein the driving part 21 can drive the pushing part 23 to move when the reaction container 4 moves to the cup discarding station, the pushing part 23 is used for separating and pushing the reaction container 4 from the dispensing tray 3 to a preset position, and the position detecting assembly 22 is at least used for detecting the position of the reaction container 4 after being separated from the dispensing tray 3. Through the matched driving part 21 and pushing part 23, the reaction container 4 can be conveniently and rapidly separated from the dispensing tray 3 and pushed to a preset position, and the reaction container 4 pushed to the preset position can directly or indirectly enter the collecting device to finish the cup throwing work. The driving part 21 directly controls the structure of the movement of the pushing part 23 to be matched simply and easily, and can ensure that the reaction vessel 4 is pushed to a preset position accurately, thereby improving the stability and the precision of the throwing cup. Meanwhile, in the process that the driving part 21 drives the pushing part 23 to move, the position detection assembly 22 is matched, at least the state that the reaction container 4 moves in the cup throwing process can be detected, the cup throwing precision is further ensured, and the situation that the pushing part 23 does not drive the reaction container 4 to a preset position at a time in the cup throwing process to cause the reaction container 4 to be blocked in the cup throwing mechanism 2 at a certain time is avoided, so that the subsequent cup throwing work is influenced. The staff can in time clear up the reaction vessel 4 that blocks up in abandoning cup mechanism 2 according to the condition of reaction vessel 4 motion position that position detection subassembly 22 detected, avoids seriously piling up the damage of reaction vessel 4 down and influences the going on of follow-up throwing cup work.
In an embodiment, referring to fig. 1, 2 and 3, the cup feeding station, the sample adding and mixing station, the detecting station and the cup discarding station are arranged along the circumference of the body 1, the dispensing disc 3 is rotatably connected to the body 1, and the rotation of the dispensing disc 3 can drive the reaction container 4 to rotate to each station according to time sequence among the stations. The incubation unit includes drive assembly 5, and drive assembly 5 sets up in body 1, and drive assembly 5 is connected with the minute injection dish 3 for drive the circumference rotation of minute injection dish 3 along body 1, the specific structure of minute injection dish 3 to drive assembly 5 and be connected with it is here not repeated.
The body 1 is equipped with out the rim of a cup 11 corresponding to abandoning the cup station, abandons cup mechanism 2 and has first passageway 24, and first passageway 24 extends along the radial direction of body 1 and communicates with out the rim of a cup 11, and the promotion portion 23 can drive reaction vessel 4 along first passageway 24 and move to the position of predetermineeing. In the dispensing tray 3, a plurality of groove structures with openings are arranged on the edge of the dispensing tray 3 along the circumferential direction to form a sawtooth-like disc-shaped structure, and the reaction container 4 can enter and exit the grooves through the openings to realize connection or disconnection of the reaction container 4 and the dispensing tray 3. Optionally, in order to facilitate the rotation of the dispensing disc 3 and to facilitate the rapid entry or removal of the reaction vessel 4 from the opening while the reaction vessel 4 is driven to rotate, the reaction vessel 4 includes a vessel body 42 and a vessel shoulder 41 protruding axially outwardly, and when the reaction vessel 4 enters the groove of the dispensing disc 3, the reaction vessel 4 is supported on the dispensing disc 3 by the arrangement of the vessel shoulder 41 having a size larger than the size of the groove, and the reaction vessel 4 is in clearance fit with the groove. When the dispensing disc 3 rotates to a corresponding cup inlet station or cup discarding station, the opening can be opposite to the cup inlet or outlet 11 so as to directly load or unload a cup on or from the dispensing disc 3.
The driving part 21 comprises a driving motor 211 and a connected screw rod 212, the pushing part 23 is in threaded connection with the screw rod 212, the driving motor 211 can drive the screw rod 212 to rotate, and the rotation of the screw rod 212 drives the pushing part 23 to move along the extending direction of the first channel 24. The length direction of the screw 212 is parallel to the extending direction of the first channel 24, and the screw 212 is in threaded connection with the pushing part 23, so that the rotation of the screw 212 driven by the driving motor 211 is converted into linear motion of the pushing part 23 along the extending direction of the first channel 24, and the motion of driving the pushing part 23 to move can be realized through the cooperation of the simple structure, so that the stability and the motion precision of the motion of the pushing part 23 can be accurately controlled. Ensuring that the pushing part 23 can reciprocate along the extending direction of the first channel 24, and efficiently completing the cup throwing work.
It will be appreciated that the cup discarding mechanism 2 includes a mounting base 251 and a mounting plate 252 connected above the mounting base 251, the first channel 24 is provided on the mounting base 251, the driving portion 21 is located on the mounting plate 252, the mounting plate 252 extends along the radial direction of the body 1 and partially extends out of the mounting base 251 to above the body 1, so that the pushing portion 23 can move to above the reaction container 4 located at the cup discarding station, the mounting base 251 is detachably connected to the cup discarding station of the body 1, and the pushing portion 23 is disposed above the reaction container 4 to improve the stability and strength of applying force to the reaction container 4.
Optionally, the mounting plate 252 is provided with a movement channel 252a, the movement channel 252a is communicated with the first channel 24, the pushing part 23 at least partially penetrates through the movement channel 252a, and the pushing part 23 can be slidably connected with the movement channel 252a, so as to improve the accuracy of the linear movement of the pushing part 23 along the first channel 24.
Referring to fig. 4, when the reaction vessel 4 rotates to be located at the cup discarding station, since the reaction vessel 4 is of the cup structure with the vessel shoulder 41, the pushing portion 23 has a good cup pushing effect on the reaction vessel 4, so that the reaction vessel 4 can be quickly and stably separated from the opening of the dispensing tray 3 to the first channel 24 along the radial direction of the body 1. The pushing part 23 comprises a sliding block 231, the sliding block 231 is directly connected with the screw 212 in a threaded manner, the sliding block 231 partially penetrates through the moving channel 252a and is positioned below the sliding block, a shifting block 232 is detachably connected with the sliding block 231, the shifting block 232 extends along the direction of the screw 212 and stretches into the first channel 24 from top to bottom, two protruding blocks are arranged at the lower part of the shifting block 232, and a groove is formed between the two protruding blocks. The container shoulder 41 of the reaction container 4 entering the cup-discarding station can extend at least partially into the recess when the pushing part 23 is moved above the cup-discarding station. Optionally, in one of the protruding blocks on the side away from the driving motor, the side facing the groove is provided with an abutment surface 232a, and the abutment surface 232a is used for abutting against the side wall of the container shoulder 52 to push the reaction container 4 to move along the radial direction of the body 1 to be separated from the opening into the first channel 24.
Alternatively, for the projection provided, the surface thereof facing the side of the first passage 24 may be flush or clearance-fitted with the lower surface of the container shoulder 41 of the reaction container 4 at the time of dispensing disc 3. When the two are in clearance fit, the surface of the projection facing the side of the first channel 24 is located above the lower surface of the container shoulder 41, as seen in the height direction of the incubation unit, and the clearance between the two surfaces is not more than half the height of the container shoulder 41. To ensure that the reaction vessel 4 can be more smoothly moved into the first passage 24 in the radial direction of the body 1 when the reaction vessel 4 is separated from the dispensing tray 3, so as to avoid tilting of the reaction vessel 4 and difficulty in entering the first passage 24.
It will be appreciated that the pushing portion 23 may be provided as two clamping blocks which can be moved closer to or away from each other in the radial direction of the body 1, and the movement of the two blocks closer to or away from each other may be controlled by a driving member provided, or may be provided as other cooperating structures which can ensure that the reaction vessel 4 is pushed to the collection position, so that the reaction vessel is prevented from being accumulated in the channel, which is not illustrated here.
In an embodiment, along the extending direction of the first channel 213, the first channel 213 includes a first sub-channel 241 and a second sub-channel 242 which are communicated, the first sub-channel 241 is located above the second sub-channel 242, and the width of the first sub-channel 241 is greater than that of the second sub-channel 242, so that a stepped surface 243 is formed between the two, and along the height direction of the incubation unit, the stepped surface 243 is flush or clearance fit with the surface of the protruding block close to the first channel 24. For the first sub-channel 241 and the second sub-channel 242 provided, the shape of the cross section thereof is the shape of the cross section of the reaction vessel 4 having the vessel shoulder 41 along the extending direction of the first channel 24, and the width of the second sub-channel 242 is equal to or larger than the diameter of the vessel body 42 while being smaller than the width of the vessel shoulder 41 and is at most not larger than 5mm of the diameter of the vessel body 42. The width of the first sub-channel 241 is greater than the diameter of the container shoulder 41. When the pushing part 23 pushes the reaction container 4 to enter the first channel 24 through the matched design of the first sub-channel 241 and the second sub-channel 242, the reaction container 4 can be limited in a channel with a limited space, the lower surface of the container shoulder 41 in the reaction container 4 is contacted with the step surface 243, so that when the pushing part 23 pushes the reaction container 4 out to enter the first channel 24, the reaction container 4 can directly enter the first channel 24 along the radial direction, and the situation that skew occurs due to uneven stress when pushing the reaction container 4 is avoided through a shape-adapting mode, so that the reaction container 4 is accumulated in the first channel 24 and cannot be pushed to a fixed collecting position by the pushing part 23.
Optionally, the mounting base 212 further includes a second channel 243 in communication with the first channel 24, and the pushing portion 23 is capable of pushing the reaction vessel 4 from the first channel 24 into the second channel 243. As for the second passage 243 provided for communication with the collecting means for collecting the used reaction vessel 4, the diameter of the second passage 243 is at least larger than the height of the reaction vessel 4 so that the reaction vessel 4 can smoothly enter the collecting means from the second passage 243. The extending direction of the second passage 243 may be perpendicular to the extending direction of the first passage 213 or inclined downward at a predetermined angle, so long as the reaction container 4 is not stacked or caught in the second passage 243, and is not particularly limited.
It will be appreciated that the predetermined positions referred to above may be different according to different mating structures of the first channel 24, the second channel 243, etc. provided in the mounting base 251. For example, when the first passage 24 and the second passage 243 intersecting as described above are provided, the preset position thereof is the intersection position at which the two passages intersect. As long as the reaction vessel 4 can be pushed to a predetermined position while the reaction vessel 4 can be directly or indirectly introduced into the collecting device, there is no particular limitation.
In an embodiment, the driving portion 2 further includes a limiting assembly, the limiting assembly is used for limiting the movement of the pushing portion 23, the limiting assembly includes a stroke portion 27 and a limiting portion 28, the stroke portion 27 is located on the pushing portion 23, the limiting portion 28 is located on a side, close to the screw 212, far from the driving motor 211, and the abutment of the stroke portion 27 and the limiting portion 28 is used for limiting the movement of the pushing portion 23 along the extending direction of the first channel 24. Through the cooperation of the limiting part 28 and the travel part 27, the screw 212 can avoid the push part 23 from moving excessively when the driving part 2 fails, limit the movement of the push part 23 to the limited range for reciprocating movement, and improve the stability and precision of the movement of the push part 23. It will be appreciated that the limiting assembly may be configured as other limiting assemblies capable of limiting, and is not specifically limited herein.
In an embodiment, the pushing portion 23 further includes a limiting structure, where the limiting structure is used to limit the movement posture of the pushing portion 23, and the limiting structure includes a guiding portion and an abutting portion 29, where the guiding portion is located at the lower portion of the sliding block 231 and is inserted into the movement channel 252a of the mounting plate 252, and the width of the guiding portion is slightly smaller than the width of the movement channel 252a, and when the pushing portion 23 moves along the movement channel 252a, the guiding portion plays a role in limiting and guiding, and meanwhile, because the guiding portion is inserted into the movement channel 252a, the screw 212 can be prevented from driving the pushing portion 23 to move excessively when the driving portion 2 fails, so that the movement of the pushing portion 23 is limited to reciprocate in a limited range, and stability and precision of the movement of the pushing portion 23 are improved. It will be appreciated that the limiting structure may be configured as other limiting components capable of limiting, which is not specifically limited herein.
Optionally, the abutting portion 29 is symmetrically disposed on two sides of the sliding block 231 and abuts against the upper surface of the mounting plate 252, when the pushing portion 23 is driven by the screw 212 to move along the extending direction of the moving channel 252a, due to the action of screw friction force, micro deflection of the pushing portion around the screw 212 may occur, and the micro deflection may directly act on the bottom shifting block 232, at this time, in working engineering of the shifting block 232, the center of the abutting surface 232a of the protruding block cannot be guaranteed to contact with the container shoulder 41 of the reaction container 4, and further, under the condition that the reaction container 4 is pushed by the bias of the shifting block 232, friction force is generated between one side of the reaction container 4 and the side wall of the first sub-channel 241, and the biasing pushing force of the shifting block 232 is forced to act on the reaction container 4, so that stress damage of the reaction container 4 is very easy to cause occurrence of channel blockage. The occurrence of the above-mentioned situation can be avoided through the arrangement of the abutting part, the accuracy of the alignment of the pushing part 23 and the reaction vessel 4 is ensured, and the stability of the pushing cup is further improved.
In one embodiment, referring to fig. 5, the position detecting assembly 22 includes at least one detecting portion 221, and the detecting portion 221 is at least at a preset position. Through the detection portion 31 that sets up, can detect at least that reaction vessel 4 reaches the preset position in abandoning cup mechanism 2, the promotion portion 23 promotes reaction vessel 4 and can be detected by detection portion 221 in the position of first passageway 24, and the condition that does not promote in place and detain in first passageway 24 appears when judging to have the promotion reaction vessel 4 to remove for a time to ensure can not cause reaction vessel 4 local jam and influence the normal use of incubation unit when throwing the cup, can be convenient for the staff simultaneously can in time solve the jam problem in order to get rid of the trouble.
Optionally, the plurality of detecting portions 221 may be sequentially arranged along the extending direction of the first channel 24, so as to realize real-time monitoring of the reaction container 4, and can learn the positions of the reaction container 4 in the first channel 24 at different times in the time period of the movement of the first channel 24, and whether the reaction container 4 leaves the position at the next time to enter the next position, so as to improve the detection effect on the position state of the reaction container 4, discover problems in time, and avoid congestion in the first channel 24.
When the cup discarding mechanism 2 is provided with the first channel 24 and the second channel 243 which are communicated, the second channel 243 is used for guiding the reaction container 4 into the collecting device, and the detecting part 221 may be disposed at a position corresponding to the second channel 243 for detecting the position of the reaction container 4 in the second channel 243. By setting the position corresponding to the second channel 243 set by the detecting part 221, after the detecting part 221 detects that the position of the reaction container 4 exceeds the preset time, a warning is sent, which may be that the collecting device is filled with the reaction container 4 and overflows to the second channel 243, so that a worker is reminded of timely processing, the normal operation of the incubation unit is ensured, and accumulation caused by backflow to the first channel 24 due to misoperation of filling the collecting device is avoided.
It is to be understood that, for the provided detecting portion 221, it may also be provided at a position of the mounting plate 253 corresponding to the pushing portion 23 in the cup discarding mechanism 2, and the detecting portion 221 is used for detecting a movement position of the pushing portion 23. The detection part 221 directly detects the position of the pushing part 23 to ensure that the pushing part 23 can move in place in the reciprocating motion process so as to push the reaction container 4 to a preset position, thereby ensuring that the reaction container 4 is not accumulated in the first channel 24 to cause blockage.
The detection unit 221 itself may be a structure that recognizes by a sense of light, for example, an optocoupler, or may be a structure that recognizes by a contact method, and is used to detect whether the reaction vessel 4 is in place, and the specific structure thereof is not particularly limited herein.
Optionally, an identifying unit may be disposed in the detecting portion 221, in the process that the reaction container 4 moves along the first channel 24, the detecting portion 221 may determine, according to a preset time, the number of times that the reaction container 4 passing through a position corresponding to the setting detecting portion 221 passes through, to determine whether a situation that the reaction container 4 is not pushed in place occurs when being pushed to move for a certain time, so that the number of times that the reaction container 4 actually passes through is smaller than the preset number of times, thereby ensuring that local congestion of the reaction container 4 is not caused when the reaction container is thrown, and affecting normal use of the incubation unit, so that a staff can timely remove a fault. For example, the identification unit may include at least one of a counter and a timer for limiting the number of times the reaction container 4 is detected within a preset time to a preset number of times. By providing the counter, timer, etc., the in-place detection of the reaction container 4 can be combined with the timing, and the presence or absence of the reaction container 4 accumulation in the first passage 24 can be more accurately determined by the time interval between the passage of the reaction container 4 at the corresponding position, the number of times of passage of a certain period of time, the time when the reaction container 4 is detected at the position, etc.
In an embodiment, the control unit may further include a middle position machine and a lower position machine, the middle position machine is configured to receive signals from the lower position machine and send instructions to the lower position machine, and the lower position machine is configured to execute the instructions of the middle position machine to control the mechanism to implement corresponding actions and feed back the executed corresponding action forming signals to the middle position machine. The lower computer may include a control unit, where the electronic components, such as the driving motor, the optocoupler, and the counter, are correspondingly disposed, and for each electronic component in the foregoing, the control unit may be connected to the electronic components, so that incubation operation of the incubation unit may be orderly implemented, which is not described in detail herein.
The present application provides a sample analyzer, which includes the cup discarding mechanism 2 described in the foregoing, and will not be described herein.
The present application also provides a cup discarding method, which is used for the cup discarding mechanism 2 in the foregoing, and specifically includes:
when the fact that the dispensing disc 3 drives the reaction container 4 to move to the cup discarding station is detected, the driving part 21 is controlled to drive the pushing part 23 to move so as to separate and push the reaction container 4 from the dispensing disc 3 to a preset position, and in the process of pushing the reaction container 4 to the preset position, if the reaction container 4 detected by the position detecting component 22 meets preset conditions, the reaction container 4 is judged to be in a normal motion state in the cup discarding mechanism 2.
The manner of combining the control driving part 21 to drive the pushing part 23 to move and the position detecting component 22 is that the reaction vessel 4 pushed by the pushing part 23 is monitored directly or indirectly in the movement process, if the detected reaction vessel 4 can be maintained under the condition that the detected reaction vessel 4 meets the preset condition all the time, the cup throwing work in the cup throwing mechanism 2 is in a normal running state. When the detected reaction vessel 4 does not meet the preset condition, the position where the problem occurs can be judged according to the detected condition of the specific condition which is not met, so that the problem can be effectively solved in time, and the reaction vessel 4 is prevented from being accumulated in the channel.
In one embodiment, the detecting portion 221 is at least located at a preset position in the first channel 24, and the cup discarding mechanism 2 pushes the reaction container 4 to move to the preset position, so that the cup discarding operation can be completed. The cup discarding method comprises the following steps: in the process of separating and pushing the reaction container 4 from the dispensing tray 3 to the preset position by controlling the driving part 21 to drive the pushing part 23 to move, if the reaction container 4 which can be detected by the preset time detecting part 221 reaches the preset position at each interval, the reaction container 4 is judged to be in a normal motion state in the cup discarding mechanism 2, or if the number of times that the reaction container 4 detected by the preset time detecting part 221 passes through the preset position is preset, the reaction container 4 is judged to be in a normal motion state in the cup discarding mechanism 2; otherwise, the detecting unit 221 issues an alarm signal to control the stop of the reaction vessel 4 when it is judged that the reaction vessel 4 is accumulated in the cup discarding mechanism 2. The detection unit 221 provided at a predetermined position can detect and count the in-place condition of the reaction vessel 4 moving along the first passage 24.
The preset data set by the identification unit in the detection unit 221 is determined according to the specific conditions such as the rotation speed of the dispensing tray 3, the time required by the cup discarding mechanism 2 when the reaction containers 4 are thrown, etc., and the preset data may be the preset times detected by the counter when the reaction containers 4 pass through in a period of time, or the preset time when the two adjacent reaction containers 4 reach the preset position is detected, and the preset time may be detected by the timer in the identification unit. Taking a preset number of times set in advance as an example, the number of times of counting the reaction containers 4 detected by the counter every 1 hour is set. When the cup discarding mechanism 2 drives the reaction container 4 to reach the preset position for completing one cup discarding operation in 1 hour during the cup discarding process, each time the reaction container 4 is at the preset position, the reaction container 4 can be detected by the detecting part 221 and recorded as 1 time by the timer. After one hour, comparing the detection times calculated by the counter with preset times, if the detection times are equal to the preset times, the cup throwing mechanism 2 is normal in each cup throwing operation, and the detection can be carried out continuously for the next hour again. If the number of detections is less than the preset number, it means that there may be at least one time of cup throwing, the reaction vessel 4 does not reach the preset position, and one or more subsequent reaction vessels 4 are stacked in the channel. The detection unit 221 issues an alarm signal and controls the stop of the detection until the worker removes the reaction containers 4 stacked in the first passage 24, and then restarts the detection to repeat a new timing detection.
In an embodiment, the detecting portion 221 may be further disposed along the extending direction of the first channel 24 and disposed at one or more positions before the preset position, and the cup discarding method includes: before the driving part 21 is controlled to drive the pushing part 23 to move and separate and push the reaction container 4 from the dispensing tray 3 to a preset position, if the detecting part 221 can detect the reaction container 4 at the corresponding position and the detected same reaction container is maintained at the detection position for less than the preset time, the reaction container 4 is judged to be in a normal motion state in the cup discarding mechanism, otherwise, the first channel 24 is judged to have accumulation of the reaction container 4, and the detecting part 221 sends out an alarm signal and controls to stop. Specifically, the timer set by the identification unit in the detection portion 221 can time the time when the reaction container 4 is identified by the identification unit, if the cup discarding mechanism 2 drives the reaction container 4 to move to realize normal operation of the cup throwing, the time when the reaction container 4 passes through the detection portion 221 and is identified by the detection portion may not exceed the preset time according to the speed of the reaction container 4 moving in the first channel 24. When the time of the reaction vessel 4 identified by the detection section 221 exceeds a preset time, it indicates that the reaction vessel 4 may be or has been accumulated at the position where the detection section 221 is provided, at least one reaction vessel 4 is blocked in the first passage 24. The detection unit 221 accordingly gives an alarm signal to control the stop until the operator removes the reaction container 4 accumulated in the first passage 24 and then restarts the reaction container.
Alternatively, the detecting portion 221 may be provided at a position on the mounting plate on the side of the end portion of the screw 212 for restricting the movement of the pushing portion 23. When the second driving part 22 is controlled to move to drive the pushing part 23 to move in the above, the setting of the position and the time sequence can be realized by the correspondingly arranged detection part 221, and the situation that the reaction vessel 4 moves in the first channel 24 can be indirectly detected by the in-place detection of the pushing part 23. When the pushing part 23 moves to the position where the reaction container 4 reaches the preset position or above the reaction container 4 of the cup discarding station, the detection part 221 recognizes the position of the pushing part 23 to control and stop, and after the detection part 221 detects the pushing part 23, the driving part 22 is controlled to reverse according to the preset time sequence to enable the pushing part 23 to reversely move to return to the initial position or perform the cup discarding work.
In an embodiment, when detecting that the dispensing tray 3 drives the reaction container 4 to move to the cup discarding station, in order to achieve the in-place detection, the detecting portion 221 is further disposed on the body 1 corresponding to the cup discarding station. Before the reaction container 4 is pushed to be separated from the dispensing tray 3, the detection part 221 can detect the position where the dispensing tray 3 drives the reaction container 4 to move, and when the reaction container 4 is detected to move to the cup discarding station, the detection part 221 can send an in-place signal to control the dispensing tray 3 to stop. The detection unit 221 serves as an in-place detection device, and recognizes that the reaction container 4 arrives at the cup discarding station, and after the reaction container arrives in place, can form an in-place signal, which is sent to the driving unit 21 of the cup discarding mechanism 2 and the driving unit 5 via the control unit. After receiving the in-place signal, the driving assembly 5 controls the dispensing disc 3 to stop moving, and the driving part 21 starts the pushing part 23 at the initial position to start the cup throwing operation. During the process of moving the reaction vessel 4 along the first channel 24, the detection parts 221 arranged at different positions start to work, and if any detection part 221 positioned in the first channel 24 or at a preset position detects the accumulation condition according to the method, an alarm signal can be sent to control the whole cup throwing work or the sample analysis work to stop until the fault is removed, and then the operation is restarted.
Similarly, the position detection may be performed by the detection unit 221 provided in the second passage 243 in the manner described above, and will not be described in detail here.
The embodiments of the present application have been described above, the foregoing description is exemplary, not exhaustive, and not limited to the embodiments disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the various embodiments described. The terminology used herein was chosen in order to best explain the principles of the embodiments, the practical application, or the improvement of technology in the marketplace, or to enable others of ordinary skill in the art to understand the embodiments disclosed herein.

Claims (10)

1. The utility model provides a abandon a cup mechanism of incubation unit, its characterized in that, incubation unit includes body and swing joint's minute notes dish, minute notes dish is used for placing reaction vessel, minute notes dish is relative the motion of body can drive reaction vessel moves to abandoning a cup station, abandon a cup station setting abandon a cup mechanism, abandon a cup mechanism includes:
the driving part can drive the pushing part to move when the reaction container moves to the cup discarding station, and the pushing part is used for separating and pushing the reaction container from the dispensing disc to a preset position;
and a position detecting unit for detecting at least a position of the reaction vessel which moves after being separated from the dispensing tray.
2. The cup discarding mechanism according to claim 1, wherein the dispensing tray is rotatably connected to the main body, the main body is provided with a cup outlet corresponding to the cup discarding station,
the cup discarding mechanism is provided with a first channel, the first channel extends along the radial direction of the body and is communicated with the cup outlet, and the pushing part can drive the reaction container to move to the preset position along the first channel.
3. The cup-discarding mechanism according to claim 2, wherein the driving section comprises a driving motor and a screw rod connected thereto,
the pushing part is in threaded connection with the screw rod, the driving motor can drive the screw rod to rotate, and the rotation of the screw rod drives the pushing part to move along the extending direction of the first channel.
4. The cup-discarding mechanism according to claim 3, wherein the pushing section comprises a slider and a dial, the slider is provided with a stopper structure for restricting a movement posture of the pushing section,
the limiting structure comprises a guide part and an abutting part, wherein the guide part is used for limiting the sliding block to move along the extending direction of the first channel.
5. The cup-discarding mechanism according to claim 4, wherein the abutment portions are symmetrically disposed on both sides of the slider for restricting rotation of the pushing portion about the screw.
6. The cup-discarding mechanism according to one of claims 1 to 5, wherein the position detection assembly comprises at least one detection section, which is located at least in the preset position.
7. A sample analyzer comprising a disposal cup mechanism as claimed in any one of claims 1 to 6.
8. The utility model provides a abandon a cup method which characterized in that is used for incubating the unit, it includes the branch annotates the dish and places the reaction vessel on it and set up in abandoning the cup mechanism of cup station to incubate the unit, abandon the cup mechanism and include complex drive portion and pushing part and position detection subassembly, abandon a cup method includes:
when the fact that the dispensing disc drives the reaction container to move to the cup discarding station is detected, the driving part is controlled to drive the pushing part to move, so that the reaction container is separated from the dispensing disc and pushed to a preset position, and in the process of pushing the reaction container to the preset position, if the reaction container detected by the position detecting component meets preset conditions, the reaction container is judged to be in a normal movement state in the cup discarding mechanism.
9. The cup discarding method according to claim 8, wherein the position detection assembly comprises at least one detection portion located at least at a preset position, the detection method comprising:
controlling the driving part to drive the pushing part to move, and in the process of separating and pushing the reaction container from the dispensing tray to the preset position, judging that the reaction container is in a normal movement state in the cup discarding mechanism if the reaction container which can be detected by the detecting part reaches the preset position at each preset time interval, or judging that the reaction container is in a normal movement state in the cup discarding mechanism if the number of times of passing the preset position detected by the detecting part at the preset time is preset times; otherwise, judging that the reaction container is accumulated in the cup discarding mechanism, and sending an alarm signal by the detection part and controlling to stop.
10. A cup discarding method according to claim 8 or 9, wherein the cup discarding mechanism comprises a first channel, the detection section is arranged along the extension direction of the first channel, and the cup discarding method comprises:
and controlling the driving part to drive the pushing part to move, and before the reaction container is separated from the dispensing disc and pushed to the preset position, judging that the reaction container is in a normal movement state in the cup discarding mechanism if the detection part can detect the reaction container at the corresponding position and the detected same reaction container is maintained at the detection position for less than the preset time, otherwise, judging that the reaction container is accumulated in the first channel, and sending an alarm signal by the detection part and controlling to stop.
CN202111672412.6A 2021-12-31 2021-12-31 Cup discarding mechanism of incubation unit, sample analyzer and cup discarding method Pending CN116413463A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111672412.6A CN116413463A (en) 2021-12-31 2021-12-31 Cup discarding mechanism of incubation unit, sample analyzer and cup discarding method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202111672412.6A CN116413463A (en) 2021-12-31 2021-12-31 Cup discarding mechanism of incubation unit, sample analyzer and cup discarding method

Publications (1)

Publication Number Publication Date
CN116413463A true CN116413463A (en) 2023-07-11

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202111672412.6A Pending CN116413463A (en) 2021-12-31 2021-12-31 Cup discarding mechanism of incubation unit, sample analyzer and cup discarding method

Country Status (1)

Country Link
CN (1) CN116413463A (en)

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