CN116406709B - Grease composition and application thereof - Google Patents
Grease composition and application thereof Download PDFInfo
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- CN116406709B CN116406709B CN202111681243.2A CN202111681243A CN116406709B CN 116406709 B CN116406709 B CN 116406709B CN 202111681243 A CN202111681243 A CN 202111681243A CN 116406709 B CN116406709 B CN 116406709B
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- 239000000203 mixture Substances 0.000 title claims abstract description 67
- 239000004519 grease Substances 0.000 title claims abstract description 16
- 102000004219 Brain-derived neurotrophic factor Human genes 0.000 claims abstract description 29
- 108090000715 Brain-derived neurotrophic factor Proteins 0.000 claims abstract description 29
- 229940077737 brain-derived neurotrophic factor Drugs 0.000 claims abstract description 23
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims abstract description 11
- 230000013016 learning Effects 0.000 claims abstract description 10
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 9
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 9
- 235000013336 milk Nutrition 0.000 claims abstract description 8
- 239000008267 milk Substances 0.000 claims abstract description 8
- 210000004080 milk Anatomy 0.000 claims abstract description 8
- 235000015872 dietary supplement Nutrition 0.000 claims abstract description 6
- 230000007087 memory ability Effects 0.000 claims abstract description 4
- 239000000843 powder Substances 0.000 claims abstract description 4
- 235000013305 food Nutrition 0.000 claims description 17
- 235000016709 nutrition Nutrition 0.000 claims description 12
- 235000013350 formula milk Nutrition 0.000 claims description 8
- 230000001737 promoting effect Effects 0.000 claims description 8
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 5
- 230000000694 effects Effects 0.000 claims description 5
- 229930195729 fatty acid Natural products 0.000 claims description 5
- 239000000194 fatty acid Substances 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
- 230000000295 complement effect Effects 0.000 claims description 3
- 230000003988 neural development Effects 0.000 claims description 2
- -1 C22 fatty acids Chemical class 0.000 claims 1
- 230000030363 nerve development Effects 0.000 abstract description 3
- 235000013402 health food Nutrition 0.000 abstract description 2
- 235000019197 fats Nutrition 0.000 description 21
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 10
- 230000000052 comparative effect Effects 0.000 description 9
- 230000015654 memory Effects 0.000 description 7
- 241000252212 Danio rerio Species 0.000 description 6
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 4
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 4
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 4
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 4
- 239000005642 Oleic acid Substances 0.000 description 4
- 235000021314 Palmitic acid Nutrition 0.000 description 4
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 4
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 4
- 210000002569 neuron Anatomy 0.000 description 4
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 235000020778 linoleic acid Nutrition 0.000 description 3
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 3
- 235000012054 meals Nutrition 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 150000003626 triacylglycerols Chemical class 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 108010025020 Nerve Growth Factor Proteins 0.000 description 2
- 102000007072 Nerve Growth Factors Human genes 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 230000004641 brain development Effects 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 230000004069 differentiation Effects 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 235000021243 milk fat Nutrition 0.000 description 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000007472 neurodevelopment Effects 0.000 description 2
- 239000003900 neurotrophic factor Substances 0.000 description 2
- 230000008092 positive effect Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 239000012488 sample solution Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 238000001262 western blot Methods 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 1
- 101000993347 Gallus gallus Ciliary neurotrophic factor Proteins 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000000540 analysis of variance Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003925 brain function Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 210000003520 dendritic spine Anatomy 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000000105 evaporative light scattering detection Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000000971 hippocampal effect Effects 0.000 description 1
- 210000001320 hippocampus Anatomy 0.000 description 1
- 235000020256 human milk Nutrition 0.000 description 1
- 210000004251 human milk Anatomy 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000007996 neuronal plasticity Effects 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 238000009372 pisciculture Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 230000006886 spatial memory Effects 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 210000000225 synapse Anatomy 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1528—Fatty acids; Mono- or diglycerides; Petroleum jelly; Paraffine; Phospholipids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/16—Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Edible Oils And Fats (AREA)
Abstract
The invention provides a grease composition and application thereof. The oil and fat composition of the present invention comprises 1-oleic acid-2-palmitic acid-3-linoleic acid triglyceride OPL, 1, 3-dioleoyl-2-palmitic acid triglyceride OPO and 1, 3-dioleoyl-2-palmitic acid triglyceride LPL, wherein the mass ratio of OPL to OPO is 1:1 or more, and the sum of the mass of LPL and OPO is 40% or less based on 100% of the total mass of the oil and fat in the composition. The oil composition can promote brain-derived neurotrophic factor (BDNF) protein expression, promote or improve nerve development, and improve individual learning and/or memory ability, and can be used for preparing various health foods such as milk powder, supplementary food or nutritional supplement.
Description
Technical Field
The invention relates to an oil composition and application thereof, in particular to an oil composition comprising 1-oleic acid-2-palmitic acid-3-linoleic acid triglyceride OPL, 1, 3-dioleoyl-2-palmitic acid triglyceride OPO and 1, 3-dioleoyl-2-palmitic acid triglyceride LPL, which can improve nerve development and improve learning and/or memory ability of individuals, and can be used for preparing various health foods such as milk powder, complementary foods or nutritional supplements.
Background
Brain-derived neurotrophic factor (BDNF) is a protein synthesized in the brain with nerve growth promoting activity, and is mainly expressed in the hippocampus and cortex in the brain. BDNF is the most abundant and widely distributed neurotrophic factor in the central nervous system, and is closely related to brain development and function.
Research shows that BDNF can promote the outgrowth of neurons and the maturation of dendritic spines, and plays an important role in the survival, differentiation, growth and development of neurons. BDNF can promote the growth and differentiation of nerve cells, maintain the survival and normal functions of the nerve cells, and is closely related to the formation and maintenance of spatial memory and the intelligence development related to memory. In addition, BDNF is a key neurotrophic factor that enhances learning and memory. Regulate brain development, synapse formation, memory and learning. Promoting BDNF protein expression would be beneficial in promoting or improving neurological development, enhancing learning and/or memory in individuals. However, the mechanism of BDNF protein expression is currently under further investigation.
Disclosure of Invention
An object of the present invention is to provide a fat composition that promotes the expression of brain-derived neurotrophic factor (BDNF) protein.
Another object of the present invention is to provide the use of said fat and oil composition for the preparation of food products.
The inventor finds that the grease composition composed of various triglycerides according to a specific proportion can promote the expression of brain-derived neurotrophic factor (BDNF) protein in experimental research.
Specifically, in one aspect, the present invention provides a fat composition comprising 1-oleic acid-2-palmitic acid-3-linoleic acid triglyceride OPL, 1, 3-dioleoyl-2-palmitic acid triglyceride OPO and 1, 3-dioleoyl-2-palmitic acid triglyceride LPL, wherein the mass ratio of OPL to OPO is 1:1 or more, and the sum of the mass of LPL and OPO is 40% or less based on 100% of the total mass of fat in the composition.
1-Oleic acid-2-palmitic acid-3-linoleic acid triglyceride OPL, 1, 3-dioleoyl-2-palmitic acid triglyceride OPO and 1, 3-dioleoyl-2-palmitic acid triglyceride LPL are important milk fat components. Wherein OPO is a structured fat, and the molecular structure of the milk fat is simulated by an enzymatic transesterification technology, so that the 2-palmitic acid (Sn-2 palmitic acid) proportion is close to the breast milk level, and the OPO is applied to infant formulas. Related researches show that the unique two-position palmitic acid structure is not easy to form calcium soap during digestion, so that constipation of infants is not easy to cause, and digestion and absorption of fatty acid and calcium are easier. The two-position palmitic acid structure exists in addition to OPO configuration, and other configurations exist, such as OPL (1-oleic acid-2-palmitic acid-3-linoleic acid triglyceride), LPL (1, 3-dilinoleic acid-2-palmitic acid triglyceride), SPL (1-stearic acid-2-palmitic acid-3-linoleic acid triglyceride) and the like.
According to a specific embodiment of the present invention, in the fat and oil composition of the present invention, the mass ratio of OPL to OPO is (1 to 2.5): 1, preferably 1.2 to 1.3:1.
According to a specific embodiment of the present invention, the oil and fat composition of the present invention has a total mass of 18% to 38% of the sum of LPL and OPO. In some more specific embodiments of the invention, the sum of the masses of LPL and OPO is 18-20%. In other more specific embodiments of the invention, the sum of the masses of LPL and OPO is 28 to 32%. In other more specific embodiments of the invention, the sum of the masses of LPL and OPO is 35 to 38%.
According to a specific embodiment of the present invention, in the fat and oil composition of the present invention, the mass ratio of LPL to OPO is 0.4 or more. Preferably, the mass ratio of LPL to OPO is (0.4-2.0): 1. in some more specific embodiments of the invention, the mass ratio of LPL to OPO is (0.43 to 0.8): 1. in other more specific embodiments of the invention, the mass ratio of LPL to OPO is (1.5-1.9): 1.
In some embodiments of the present invention, the fat compositions of the present invention have a P (16:0 palmitic acid) content of 27% to 30%, an O (18:1 oleic acid) content of 40% to 46%, and an L (18:2 linoleic acid) content of 20% to 28% based on 100% total fatty acid mass in the fat composition.
In some embodiments of the present invention, the total content of P (16:0 palmitic acid), O (18:1 oleic acid), L (18:2 linoleic acid) is 87% -98% based on 100% total fatty acid mass in the oil composition. In some embodiments of the invention P, O, L is present in an amount of 27% to 35%, 40% to 53%, 20% to 32% of each, based on 100% total content of P (16:0 palmitic acid), O (18:1 oleic acid), L (18:2 linoleic acid).
According to a specific embodiment of the present invention, in the fat and oil composition of the present invention, the mass ratio of O (18:1 oleic acid) to L is 2.2 or less, preferably (1.4 to 2.0): 1, more preferably (1.5 to 1.9): 1.
According to a specific embodiment of the present invention, the fat composition of the present invention is a triglyceride composition, consisting of C12-C22 fatty acids. In particular, the triglycerides may include one or more of the OPO, OPL, LPL, OLL, OLO, SPL, OSL, LSL, OOO, LLL, PPO, PPL or the like configurations. According to a preferred embodiment of the present invention, the total mass of OPO, LPL and OPL in the fat and oil composition of the present invention is 34% to 70%.
On the other hand, the invention also provides application of the oil composition in preparing a nutritional composition, wherein the food has the effects of promoting brain-derived neurotrophic factor (BDNF) protein expression, promoting or improving nerve development and improving individual learning and/or memory capacity.
According to a specific embodiment of the invention, the nutritional composition is a food; in some embodiments, the food product may be a milk powder, liquid milk, a complementary food, or a nutritional supplement. Preferably, the food is infant formula or infant liquid milk.
According to a specific embodiment of the present invention, the fat and oil composition of the present invention may be used in a nutritional composition (e.g., a food) in an amount of: 2% -70%. In particular, the food can be properly adjusted according to different food types. In some specific embodiments, the grease composition may be applied in an amount of 2% to 30% in the nutritional composition.
In another aspect, the present invention also provides a nutritional composition (e.g., a food product) comprising the grease composition of the present invention. Preferably, the fat composition is applied in the nutritional composition in an amount of: 2% -70%.
The oil composition and the food containing the same are beneficial to promoting the expression of brain-derived neurotrophic factor (BDNF) protein, thereby having positive effects on the development of individual nerves, learning and memory.
Drawings
FIG. 1 shows the effect of the oil and fat composition of the present invention on the promotion of the expression of brain-derived neurotrophic factor (BDNF) protein. The drawing is marked: with the same letters, the differences between groups were not significant (p > 0.05); the differences between groups without the same letters were significant (p < 0.05).
Detailed Description
In order to more clearly understand the technical features, objects and advantages of the present invention, the technical solutions of the present invention will now be described in detail with reference to specific examples, which should be understood to be only illustrative of the present invention and not limiting the scope of the present invention.
Unless specifically defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the relevant art. The content of each of the oil components in the examples was measured by a method conventional in the art. The operating conditions not specified in detail in the examples were carried out according to the usual procedures in the art.
In the invention, the configuration of triglyceride in the grease is detected by adopting high performance liquid chromatography. The detection method comprises the following steps:
instrument: high performance liquid chromatograph with evaporative light scattering detector.
Chromatographic column: and a phospholipid analysis column, wherein two columns are connected in series. Column temperature: 25 ℃. Mobile phase: n-hexane solution; flow rate: the isocratic is 1.2 mL/min. Run test time: 60 And (5) min. Sample injection amount: 20. Mu.L.
Preparation of a standard curve: standard series of working curves of 25. Mu.g/mL, 50. Mu.g/mL, 100. Mu.g/mL, 250. Mu.g/mL, 500. Mu.g/mL were prepared using flow matching, with internal standard content of 200. Mu.g/mL. And drawing a standard curve by taking the horizontal coordinate of the concentration of the standard solution and the peak area of the chromatographic peak as the vertical coordinate.
And (3) calculating results: the content of each structural fat in the sample is calculated from the formula (1):
in the formula (1): x is the content of the component to be measured in milligrams per gram;
m-the sample weight of the sample, the unit is gram;
Ci-the concentration of the component to be measured in the sample solution in micrograms per milliliter.
V-the constant volume of the sample solution in milliliters.
Example 1, fat composition and efficacy of promoting BDNF protein expression
The compositions and compositions of the grease compositions of this example are shown in Table 1. And providing oil raw materials of a comparison group, wherein the comparison groups 2-4 are LLL pure products, OPO pure products and OPL pure product raw materials respectively.
TABLE 1 composition of fat and oil compositions
In this example, the effect of feeding different lipid compositions to zebra fish on zebra fish neurological development was studied.
Test group: the study used wild type AB zebra fish, 30 zebra fish per experimental group, were set up in 3 replicates and incubated in an incubator at 28 ℃. A total of 10 groups were set up, experimental groups 1-4, comparative groups 1-5, and normal control groups (fish farming water treatment groups), respectively. Zebra fish were fed the grease compositions or triglycerides in table 1 on day a after incubation (the feeding amount of each group is 20 microliters per day based on the total amount of the grease compositions, wherein the dosage of the comparative group 2, i.e. the LLL group, is 1/3 of that of the other groups), and after day B, zebra fish samples were collected respectively, and the effect of different grease compositions on the brain-derived neurotrophic factor (BDNF) protein expression was evaluated by Western immunoblotting (Western blotting). Results were analyzed statistically using analysis of variance and Dunnett's T-test.
The experimental results are shown in FIG. 1. As can be seen from fig. 1, experimental group 2, experimental group 3, and comparative group 2, comparative group 3, and comparative group 4 all increased expression of BDNF protein, while comparative group 1 failed to increase expression of BDNF protein, as compared to the normal control group. The level of BDNF protein expression was highest in experimental group 2, no statistical difference from experimental group 3, and significant differences from experimental group 1, comparative group 2, comparative group 3, comparative group 4.
Studies have shown that BDNF plays a central regulatory role in hippocampal neuronal plasticity, and is involved in the processes of learning and memory. Therefore, the grease composition can promote the neural development of individuals such as infants, and has positive effects on the learning and memory abilities of the individuals.
Example 2 infant formula with fat and oil composition
The present example provides an infant formula of 0 to 6 months of age having a total protein content of 11.1g/100g meal, a fat content of 27.8g/100g meal and a carbohydrate content of 52.9g/100g meal. Wherein the fat comprises OPL, OPO and LPL, and the ratio of OPL, OPO and LPL to total triglyceride in the infant formula is 13.9%, 11.6% and 5.8%, respectively.
Claims (14)
1. The grease composition comprises 1-oleic acid-2-palmitic acid-3-linoleic acid triglyceride OPL, 1, 3-dioleoyl-2-palmitic acid triglyceride OPO and 1, 3-dioleoyl-2-palmitic acid triglyceride LPL, wherein the mass ratio of OPL to OPO is 1.3-2.5: 1, and the sum of the mass of LPL and OPO is 18-38% based on 100% of the total mass of grease in the composition.
2. The grease composition according to claim 1, wherein the sum of the mass of LPL and OPO is 28 to 32% based on 100% of the total mass of grease in the composition.
3. The fat and oil composition according to claim 1 or 2, wherein the mass ratio of LPL to OPO is 0.4 or more.
4. The fat and oil composition according to claim 3, wherein the mass ratio of LPL to OPO is (0.4 to 2.0): 1.
5. The fat and oil composition according to claim 4, wherein the mass ratio of LPL to OPO is (0.43 to 0.8): 1.
6. The fat or oil composition according to claim 1, which is a triglyceride composition composed of C12 to C22 fatty acids.
7. The use of the oil and fat composition according to any one of claims 1 to 6 for preparing a nutritional composition, wherein the nutritional composition has the effects of promoting brain-derived neurotrophic factor (BDNF) protein expression, promoting or improving neural development, and improving learning and/or memory ability of an individual.
8. The use according to claim 7, wherein the nutritional composition is a food product.
9. The use according to claim 8, wherein the food product is a milk powder or a liquid milk.
10. The use according to claim 8, wherein the food product is a complementary food product.
11. The use according to claim 8, wherein the food product is a nutritional supplement.
12. The use according to claim 8, wherein the food product is an infant formula or infant liquid milk.
13. Use according to any one of claims 8-12, wherein the fat composition is used in a nutritional composition in an amount of: 2% -70%.
14. A nutritional composition comprising the fat composition according to any one of claims 1 to 6; the application amount of the oil composition in the nutritional composition is as follows: 2% -70%.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111681243.2A CN116406709B (en) | 2021-12-31 | 2021-12-31 | Grease composition and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111681243.2A CN116406709B (en) | 2021-12-31 | 2021-12-31 | Grease composition and application thereof |
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| CN116406709A CN116406709A (en) | 2023-07-11 |
| CN116406709B true CN116406709B (en) | 2024-06-14 |
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| AU2021303520A1 (en) * | 2020-07-10 | 2023-02-23 | Bunge Lipid Enzymtec Sdn Bhd. | Fat composition |
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| CN108244273A (en) * | 2016-12-29 | 2018-07-06 | 丰益(上海)生物技术研发中心有限公司 | A kind of fat or oil composition and preparation method thereof |
| CN108132338B (en) * | 2017-12-21 | 2020-12-15 | 江南大学 | Similarity evaluation method for human milk substitute lipids |
| CN110089581A (en) * | 2019-05-31 | 2019-08-06 | 江南大学 | A kind of fat or oil composition |
| KR20210047991A (en) * | 2019-10-22 | 2021-05-03 | 주식회사 삼양사 | Method for preparing triglyceride with high yield through wet fractionation using solvent mixture |
| CN112741163A (en) * | 2019-10-31 | 2021-05-04 | 内蒙古伊利实业集团股份有限公司 | Oil composition and application thereof in food |
| MX2022011189A (en) * | 2020-04-09 | 2022-11-14 | Nestle Sa | Method for manufacturing sn-2 palmitic triacylglycerols. |
| CN113080458A (en) * | 2020-12-07 | 2021-07-09 | 黑龙江飞鹤乳业有限公司 | Intelligence-promoting nutritional composition |
| CN115232842A (en) * | 2022-07-27 | 2022-10-25 | 中国农业科学院油料作物研究所 | Preparation method of breast milk substitute fat with controllable OPL/OPO/LPL ratio and product thereof |
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| AU2021303520A1 (en) * | 2020-07-10 | 2023-02-23 | Bunge Lipid Enzymtec Sdn Bhd. | Fat composition |
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