CN116392562A - 一种饮品及其用途和制备方法 - Google Patents
一种饮品及其用途和制备方法 Download PDFInfo
- Publication number
- CN116392562A CN116392562A CN202211526155.XA CN202211526155A CN116392562A CN 116392562 A CN116392562 A CN 116392562A CN 202211526155 A CN202211526155 A CN 202211526155A CN 116392562 A CN116392562 A CN 116392562A
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- parts
- ginseng
- flower
- mulberry
- beverage
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
本发明涉及中药技术领域，具体涉及一种饮品及其用途和制备方法，该饮品由下述原料制备而成：桑椹、葛根、杜仲、桑叶、雅连、青钱柳、藤茶、人参花、三七花、铁皮石斛花、莲子心、桑树皮、姜黄、铁皮石斛、冬虫夏草、花旗参、红景天、川芎、芹菜籽、沙棘籽、茯苓、青果、人参。药效学试验表明，本发明饮品具有很好的辅助降血压、降血糖、降血脂的作用。
Description
技术领域
本发明涉及中药技术领域，具体涉及一种饮品及其用途和制备方法。
技术背景
“三高症”是指高血压、高血糖(糖尿病)和高脂血症。三高症往往没有明显症状，常常是在体检和化验时发现。高血脂又叫血脂异常，是指抽血检查中发现甘油三脂升高、总胆固醇升高、高密度脂蛋白(常称为“好胆固醇”)降低、低密度脂蛋白(常称为“坏胆固醇”)升高。高血脂的危险在于其以后带来的影响，往往会出现动脉硬化、高血压、冠心病、中风等心脑血管问题，血脂异常还常常合并脂肪肝、糖尿病、高血压等。高血糖的发病率逐年升高，除了一部分血糖过高，诊断为糖尿病外，还有许多人属于糖尿病前期，空腹血糖增高，特别是餐后血糖增高，出现糖耐量异常。凡体重超重、家族中有糖尿病、空腹血糖偏高者，除了要测空腹血糖外，还要测餐后血糖或做口服葡萄糖耐量试验检查，更能早期发现和确诊糖尿病和血糖异常。高血压往往开始时是间断高血压，如果不能得到有效控制，就会发展成为持续性高血压。通过饮食控制和运动而减轻体重，防止肥胖至关重要，体重的控制有利于三高症的缓解。平时还要注意劳逸结合，避免长期过劳和情绪紧张。血脂、血糖、血压增高，经运动、饮食、生活方式调整，仍不能改善者，要服用降脂、降糖、降压药物，以预防心脑血管病发生。并及时监测血脂、血糖、血压，调整药物剂量。
“三高症”不仅是最常见的综合性代谢障碍性疾病，同时也是引发各类心血管疾病发生的主要危险因素，可对患者身心健康和生活质量造成诸多不良影响，因此，需积极探寻有效的管理方案预防该疾病发生和发展。
发明内容
基于上述原因，申请人经过若干次创造性的劳动，获得了一种具有辅助治疗三高症的饮品，该饮品由下述原料制备而成：桑椹、葛根、杜仲、桑叶、雅连、青钱柳、藤茶、人参花、三七花、铁皮石斛花、莲子心、桑树皮、姜黄、铁皮石斛、冬虫夏草、花旗参、红景天、川芎、芹菜籽、沙棘籽、茯苓、青果、人参。药效学试验表明，本发明饮品具有很好的辅助降血压、降血糖、降血脂的作用。
本发明通过下述技术方案实现的。
一种饮品，该饮品由下述原料制备而成：桑椹、葛根、杜仲、桑叶、雅连、青钱柳、藤茶、人参花、三七花、铁皮石斛花、莲子心、桑树皮、姜黄、铁皮石斛、冬虫夏草、花旗参、红景天、川芎、芹菜籽、沙棘籽、茯苓、青果、人参。
所述的一种饮品，其中：桑椹10-15重量份、葛根10-15重量份、杜仲5-10重量份、桑叶5-10重量份、雅连1-3重量份、青钱柳3-5重量份、藤茶18-25重量份、人参花3-5重量份、三七花4-6重量份、铁皮石斛花1-3重量份、莲子心1-2重量份、桑树皮5-10重量份、姜黄4-6重量份、铁皮石斛3-5重量份、冬虫夏草2-4重量份、花旗参10-15重量份、红景天30-40重量份、川芎10-20重量份、芹菜籽40-60重量份、沙棘籽40-50重量份、茯苓5-10重量份、青果5-10重量份、人参4-6重量份。
所述的一种饮品，其中：桑椹12重量份、葛根12重量份、杜仲8重量份、桑叶8重量份、雅连2重量份、青钱柳4重量份、藤茶22重量份、人参花4重量份、三七花5重量份、铁皮石斛花2重量份、莲子心1.5重量份、桑树皮8重量份、姜黄5重量份、铁皮石斛4重量份、冬虫夏草3重量份、花旗参12重量份、红景天35重量份、川芎15重量份、芹菜籽50重量份、沙棘籽45重量份、茯苓8重量份、青果8重量份、人参5重量份。
所述的一种饮品，在制备辅助降压药物中的应用。
所述的一种饮品，在制备辅助降糖药物中的应用。
所述的一种饮品，在制备辅助降脂药物中的应用。
所述的一种饮品，在食用时用沸水浸泡10-20分钟之后，放凉即可引用。
所述的一种饮品，其中饮品用沸水浸泡不低于10次。
具体实施方式
为使本发明的目的、技术方案和优点更加清楚明了，下面结合具体实施方式，对本发明进一步详细说明。应该理解，这些描述只是示例性的，而并非要限制本发明的范围。此外，在以下说明中，省略了对公知结构和技术的描述，以避免不必要地混淆本发明的概念。
实施例1
桑椹12g、葛根12g、杜仲8g、桑叶8g、雅连2g、青钱柳4g、藤茶22g、人参花4g、三七花5g、铁皮石斛花2g、莲子心1.5g、桑树皮8g、姜黄5g、铁皮石斛4g、冬虫夏草3g、花旗参12g、红景天35g、川芎15g、芹菜籽50g、沙棘籽45g、茯苓8g、青果8g、人参5g。
上述原料混合均匀，用沸水浸泡15分钟之后，倾倒出浸泡液，备用；重复前述操作9次，合并备用浸泡液，放凉后即可引用。
实施例2
桑椹10g、葛根10g、杜仲5g、桑叶5g、雅连1g、青钱柳3g、藤茶18g、人参花3g、三七花4g、铁皮石斛花1g、莲子心1g、桑树皮5g、姜黄4g、铁皮石斛3g、冬虫夏草2g、花旗参10g、红景天30g、川芎10g、芹菜籽40g、沙棘籽40g、茯苓5g、青果5g、人参4g。
上述原料混合均匀，用沸水浸泡20分钟之后，倾倒出浸泡液，备用；重复前述操作9次，合并备用浸泡液，放凉后即可引用。
实施例3
桑椹15g、葛根15g、杜仲10g、桑叶10g、雅连3g、青钱柳5g、藤茶25g、人参花5g、三七花6g、铁皮石斛花3g、莲子心2g、桑树皮10g、姜黄6g、铁皮石斛5g、冬虫夏草4g、花旗参15g、红景天40g、川芎20g、芹菜籽60g、沙棘籽50g、茯苓10g、青果10g、人参6g。
上述原料混合均匀，用沸水浸泡10分钟之后，倾倒出浸泡液，备用；重复前述操作9次，合并备用浸泡液，放凉后即可引用。
实施例4
桑椹11g、葛根11g、杜仲6g、桑叶6g、雅连1.5g、青钱柳3.5g、藤茶19g、人参花3.5g、三七花4.5g、铁皮石斛花1.5g、莲子心1g、桑树皮6g、姜黄4.5g、铁皮石斛3.5g、冬虫夏草2.5g、花旗参11g、红景天33g、川芎12g、芹菜籽45g、沙棘籽42g、茯苓6g、青果6g、人参4.5g。
上述原料混合均匀，用沸水浸泡18分钟之后，倾倒出浸泡液，备用；重复前述操作9次，合并备用浸泡液，放凉后即可引用。
实施例5
桑椹14g、葛根14g、杜仲9g、桑叶9g、雅连2.5g、青钱柳4.5g、藤茶23g、人参花4.5g、三七花5.5g、铁皮石斛花2.5g、莲子心2g、桑树皮9g、姜黄5.5g、铁皮石斛4.5g、冬虫夏草3.5g、花旗参14g、红景天38g、川芎18g、芹菜籽55g、沙棘籽48g、茯苓9g、青果9g、人参5.5g。
上述原料混合均匀，用沸水浸泡12分钟之后，倾倒出浸泡液，备用；重复前述操作9次，合并备用浸泡液，放凉后即可引用。
试验例1
对高血压大鼠的影响
试验动物：2月龄自发性高血压大鼠。
试验药物：
试验1组：苯磺酸氨氯地平片组。
试验2组：苯磺酸氨氯地平片+实施例1组(实施例1浸泡液浓缩，干燥，得到提取物)。
试验方法：取自发性高血压大鼠，随机分组分为模型对照组、各试验组：试验1组灌胃给予苯磺酸氨氯地平片，给药量为0.05mg/kg，每天一次，连续6周；试验2组，灌胃给予苯磺酸氨氯地平片，给药量为0.05mg/kg，同时灌胃给予实施例1提取物，给药量为3g/kg,每天一次，连续6周；模型对照组给予等容量的蒸馏水，每天一次，连续6周。于末次给药3小时，通过无创尾动脉血压测量仪配套软件在电脑上获取收缩压数据。每只大鼠每次测量6-10次血压，均值作为该鼠收缩压测量值。
试验结果：见表1。
表1对自发性高血压大鼠的影响
注：与模型组比较**P<0.01,*P<0.05；与试验1组比较#P<0.05。
试验结论：上述试验数据表明，本发明的实施例1辅助苯磺酸氨氯地平，具有增强降血压的效果。
试验例2
对小鼠血糖的影响
试验动物：db/db小鼠，雌雄各半，4-6周龄。
试验药物：
试验1组：二甲双胍组。
试验2组：二甲双胍+实施例1组(实施例1浸泡液浓缩，干燥，得到提取物)。
试验方法：将db/db小鼠(雌雄各半)随机分组：模型组、试验组，各动物组正常进食，在早晨进食前30分钟，模型组每天灌胃给予蒸馏水20mL/kg,试验1组灌胃给予二甲双胍，给药量为250mg/kg,每天1次；试验2组，每天灌胃给予二甲双胍，给药量为250mg/kg，同时灌胃给予各实施例1提取物，给药量为4.5g/kg,每天1次，连续给药12周后，末次给药24h后，用血糖仪测定各组动物的血糖值。
试验结果：见表2。
表2对小鼠血糖的影响(24h后)
注：与模型组比较**P<0.01,*P<0.05；与试验1组比较#P<0.05。
试验结论：上述试验数据表明，本发明的饮品能够增加二甲双胍的降糖效果，具有辅助降糖的作用。
试验例3
对大鼠血脂的影响
试验动物：雄性SD大鼠，体质量140g-160g。
试验药物：
试验1组：非诺贝特胶囊组。
试验2组：非诺贝特胶囊+实施例1组(实施例1浸泡液浓缩，干燥，得到提取物)。
试验方法：取SD大鼠，适应性喂养维持饲料5天后，随机分组。模型组给予高脂饲料(维持饲料49.3％、蔗糖20％、猪油15％、酪蛋白12.5％、胆固醇1.2％、磷酸氢钙1.3％、石粉0.5％、胆酸钠0.2％)，空白对照组给予维持饲料，饲喂14天后，大鼠不禁食眼内眦采血，迅速分离血清，用试剂盒测定大鼠血清的高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)含量。模型组与空白对照组比较，血清甘油三酯升高，血清总胆固醇或低密度脂蛋白胆固醇升高，差异均有显著性，判定高脂血症大鼠模型成立。取上述高脂血症模型大鼠，根据TG水平将模型组分为模型对照组、各试验组：试验1组灌胃给予非诺贝特胶囊，给药量为20mg/kg，试验2组，灌胃给予非诺贝特胶囊，给药量为20mg/kg，同时灌胃给予实施例1提取物，给药量为3g/kg,模型对照组给予等容量的蒸馏水，连续给药30天后，于末次给药24h之后，大鼠不禁食眼内眦采血，迅速分离血清，用试剂盒测定大鼠血清中HDL-C、LDL-C、TG含量。
试验结果：见表3。
表3对大鼠血脂的影响
注：与模型组比较**P<0.01,*P<0.05；与试验1组比较#P<0.05。
试验结论：上述试验数据表明，本发明的饮品辅助非诺贝特，增加降血脂的效果，充分说明本发明饮品具有很好的辅助降甘油三酯的作用。
以上所述仅是本发明的优选实施方式，应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明原理的前提下，还可以做出若干改进和润饰，这些改进和润饰也应视为本发明的保护范围。
Claims (8)
1.一种饮品，其特征在于该饮品由下述原料制备而成：桑椹、葛根、杜仲、桑叶、雅连、青钱柳、藤茶、人参花、三七花、铁皮石斛花、莲子心、桑树皮、姜黄、铁皮石斛、冬虫夏草、花旗参、红景天、川芎、芹菜籽、沙棘籽、茯苓、青果、人参。
2.根据权利要求1所述的一种饮品，其中：桑椹10-15重量份、葛根10-15重量份、杜仲5-10重量份、桑叶5-10重量份、雅连1-3重量份、青钱柳3-5重量份、藤茶18-25重量份、人参花3-5重量份、三七花4-6重量份、铁皮石斛花1-3重量份、莲子心1-2重量份、桑树皮5-10重量份、姜黄4-6重量份、铁皮石斛3-5重量份、冬虫夏草2-4重量份、花旗参10-15重量份、红景天30-40重量份、川芎10-20重量份、芹菜籽40-60重量份、沙棘籽40-50重量份、茯苓5-10重量份、青果5-10重量份、人参4-6重量份。
3.根据权利要求1所述的一种饮品，其中：桑椹12重量份、葛根12重量份、杜仲8重量份、桑叶8重量份、雅连2重量份、青钱柳4重量份、藤茶22重量份、人参花4重量份、三七花5重量份、铁皮石斛花2重量份、莲子心1.5重量份、桑树皮8重量份、姜黄5重量份、铁皮石斛4重量份、冬虫夏草3重量份、花旗参12重量份、红景天35重量份、川芎15重量份、芹菜籽50重量份、沙棘籽45重量份、茯苓8重量份、青果8重量份、人参5重量份。
4.根据权利要求1-3任一项所述的一种饮品，在制备辅助降压药物中的应用。
5.根据权利要求1-3任一项所述的一种饮品，在制备辅助降糖药物中的应用。
6.根据权利要求1-3任一项所述的一种饮品，在制备辅助降脂药物中的应用。
7.根据权利要求1-3任一项所述的一种饮品，在食用时用沸水浸泡10-20分钟之后，放凉即可引用。
8.根据权利要求6所述的一种饮品，其中饮品用沸水浸泡不低于10次。
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