CN116370813A - A apply art device for microneedle operation - Google Patents
A apply art device for microneedle operation Download PDFInfo
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- CN116370813A CN116370813A CN202310440087.3A CN202310440087A CN116370813A CN 116370813 A CN116370813 A CN 116370813A CN 202310440087 A CN202310440087 A CN 202310440087A CN 116370813 A CN116370813 A CN 116370813A
- Authority
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- Prior art keywords
- microneedle
- roller
- liquid
- hollow
- outer roller
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
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- 238000000034 method Methods 0.000 claims description 10
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- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- 239000000741 silica gel Substances 0.000 claims 1
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- 239000007924 injection Substances 0.000 abstract description 5
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- 230000001225 therapeutic effect Effects 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- DIGQNXIGRZPYDK-WKSCXVIASA-N (2R)-6-amino-2-[[2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-[[(2R,3S)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S,3S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[2-[(2-amino-1-hydroxyethylidene)amino]-3-carboxy-1-hydroxypropylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxypropylidene]amino]-1,3-dihydroxypropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxybutylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1-hydroxypropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1,5-dihydroxy-5-iminopentylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxybutylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1-hydroxyethylidene]amino]hexanoic acid Chemical compound C[C@@H]([C@@H](C(=N[C@@H](CS)C(=N[C@@H](C)C(=N[C@@H](CO)C(=NCC(=N[C@@H](CCC(=N)O)C(=NC(CS)C(=N[C@H]([C@H](C)O)C(=N[C@H](CS)C(=N[C@H](CO)C(=NCC(=N[C@H](CS)C(=NCC(=N[C@H](CCCCN)C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C([C@H](CS)N=C([C@H](CO)N=C([C@H](CO)N=C([C@H](C)N=C(CN=C([C@H](CO)N=C([C@H](CS)N=C(CN=C(C(CS)N=C(C(CC(=O)O)N=C(CN)O)O)O)O)O)O)O)O)O)O)O)O DIGQNXIGRZPYDK-WKSCXVIASA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 229930194248 Licoflavone Natural products 0.000 description 1
- MEHHCBRCXIDGKZ-UHFFFAOYSA-N Licoflavone C Natural products CC(C)=CCC1=C(O)C=C(O)C(C(C=2)=O)=C1OC=2C1=CC=C(O)C=C1 MEHHCBRCXIDGKZ-UHFFFAOYSA-N 0.000 description 1
- 102000003792 Metallothionein Human genes 0.000 description 1
- 108090000157 Metallothionein Proteins 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
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- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
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- 210000001519 tissue Anatomy 0.000 description 1
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 description 1
- 229960000401 tranexamic acid Drugs 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Abstract
The present invention relates to an applicator for microneedle surgery. The operation device for the microneedle operation comprises a roller type microneedle, an outer conveying pipeline and a fluid driving mechanism; the roller type microneedle comprises a microneedle roller and a control handle; the microneedle roller comprises an outer roller and a mandrel, wherein a plurality of hollow microneedle groups are arranged on the peripheral wall of the outer roller; the middle part of the mandrel piece is provided with a supporting part which is matched with the inner wall surface of the outer roller and supports the outer roller; the supporting part is provided with a preset number of sub-liquid channels, and when each hollow microneedle group rotates to a set position, the internal channels of the hollow microneedles are respectively communicated with the corresponding sub-liquid channels; the spindle part is also provided with a main liquid channel communicated with each sub liquid channel; the outer delivery conduit includes an elastic conduit that is deformable to store energy and release energy. The operation device for the micro-needle operation is high in injection efficiency and can solve the problem that hollow micro-needles are easy to block.
Description
Technical Field
The invention relates to the technical field of medical beauty equipment, in particular to an operation device for micro-needle operation.
Background
Microneedle surgery is a medical technique for performing mechanical or physical minimally invasive injury stimulation on skin soft tissues by using a fine needle-like instrument so as to obtain therapeutic or cosmetic effects; the therapeutic or cosmetic efficacy may be enhanced by increasing its transdermal/absorptive efficiency with the aid of microneedles, along with simultaneous or stepwise administration of the drug or active ingredient.
The microneedle bodies are typically 10 to 2000 microns in height and 10 to 50 microns in diameter at the maximum. The length, size and shape of the microneedles can be individually designed according to therapeutic or cosmetic needs. Among all types of microneedles, hollow microneedles have the greatest drug loading due to their central structure, and because dermal tissues are closely arranged, hollow microneedles pierce the skin to easily block pinholes, affecting the release rate of drugs or functional components.
Disclosure of Invention
The present invention has been made in view of the above problems, and it is an object of the present invention to provide an applicator for microneedle surgery that overcomes or at least partially solves the above problems.
The applicator for microneedle surgery, comprising:
the roller type microneedle comprises a microneedle roller and a control handle; the microneedle roller comprises an outer roller, wherein the peripheral wall of the outer roller is provided with a plurality of hollow microneedle groups which are radially distributed by taking the central shaft of the outer roller as the center, each hollow microneedle group consists of hollow microneedles with the same preset number, and the hollow microneedles belonging to one hollow microneedle group are positioned on the same plane; the microneedle roller also comprises a mandrel piece, at least one end of the mandrel piece is fixedly connected with the control handle, and a supporting part which is matched with the inner wall surface of the outer roller and supports the outer roller is formed in the middle of the mandrel piece; the supporting part is provided with a preset number of sub-liquid channels, and when each hollow microneedle group rotates to a set position, the internal channels of the hollow microneedles are respectively communicated with the corresponding sub-liquid channels; the spindle part is also provided with a main liquid channel communicated with each sub liquid channel;
an outer delivery conduit for directing a flow of a liquid containing a drug and/or an efficacious component from a liquid supply to a liquid inlet of the main liquid channel;
a fluid drive mechanism for causing liquid from the liquid supply to flow through the outer delivery conduit to the liquid inlet of the main liquid channel;
the outer conveying pipeline comprises an elastic pipeline, wherein the elastic pipeline is used for storing energy by deformation in the process that the fluid driving mechanism drives the liquid to flow and two adjacent hollow microneedle groups rotate to the set position in sequence, and recovering the shape to release energy when the latter hollow microneedle group rotates to the set position.
In one embodiment, the fluid drive mechanism is a pump.
In one embodiment, the elastic tube is a silicone elastic tube.
In one embodiment, an annular sealing member is arranged at the periphery of the liquid outlet of each sub-liquid channel, so as to prevent the liquid from leaking out of the gap between the outer roller and the supporting part.
In one embodiment, the annular seal is an annular polyurethane seal.
In one embodiment, the microneedle roller further comprises two end caps, wherein the two end caps are respectively arranged at two end sides of the outer roller and fixedly connected with the mandrel member, and are used for restraining the outer roller from moving in the axial direction.
In one embodiment, the surgical device for microneedle surgery further comprises a control circuit electrically connected with the fluid drive mechanism for controlling the output power of the fluid drive mechanism.
The invention relates to an operation device for a microneedle operation, which utilizes an elastic pipeline to store energy when a fluid driving mechanism drives liquid to flow and two adjacent hollow microneedle groups sequentially rotate to a set position, and recovers the shape to release energy when the latter hollow microneedle group rotates to the set position, so that the liquid containing medicines and/or functional components enters a human body in a pulse mode in the operation process, the injection efficiency is high, and the problem that the hollow microneedle is easy to block can be solved.
Drawings
The accompanying drawings, which are included to provide a further understanding of the embodiments of the application and are incorporated in and constitute a part of this specification, illustrate embodiments of the application and together with the description serve to explain the principles of the application. It is obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained from these drawings without inventive faculty for a person skilled in the art. In the drawings:
FIG. 1 is a schematic view of an exemplary embodiment of an applicator for microneedle surgery according to the present invention;
fig. 2 is a schematic structural view of the microneedle roller of fig. 1
Reference numerals illustrate: 1. an outer conveying pipeline; 2. a fluid driving mechanism; 3. a control handle; 4. an outer drum; 5. hollow microneedles; 6. a spindle member; 7. a support section; 8. a sub-liquid channel; 9. an annular seal; 10. a main liquid channel; 11. a liquid supply; 12. an elastic pipe; 13. an end cap; 14. and a control circuit.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings. The embodiments described below by referring to the drawings are exemplary for the purpose of illustrating the present invention and are not to be construed as limiting the present invention, and various changes, modifications, substitutions and alterations may be made therein by one of ordinary skill in the art without departing from the spirit and scope of the present invention as defined by the appended claims and their equivalents.
The terms "center," "longitudinal," "transverse," "length," "upper," "lower," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "axial," "radial," "circumferential," and the like in the description of the present invention refer to an orientation or positional relationship as indicated on the drawings, merely for convenience of description and to simplify the description, and do not denote or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the invention.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. Furthermore, the terms "comprise," "include," and any variations thereof, are intended to cover a non-exclusive inclusion.
In the description of the present invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted", "connected" and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
An applicator for microneedle surgery according to an embodiment of the present invention is described below with reference to the accompanying drawings.
Referring to fig. 1, an applicator for microneedle surgery according to an embodiment of the present invention includes a roller-type microneedle, an outer delivery tube 1, and a fluid drive mechanism 2. When the roller type microneedle rolls on the skin, a plurality of micro-fine pipelines can be formed on the skin, the regeneration of collagen in the skin is stimulated, and the metabolism of the skin can be effectively promoted.
Specifically, the roller type microneedle comprises a microneedle roller and a control handle 3. As shown in fig. 2, the microneedle roller includes an outer roller 4, and a plurality of hollow microneedle groups radially distributed around a central axis of the outer roller 4 are disposed on a peripheral wall of the outer roller 4, and the number of the hollow microneedle groups may be specifically determined according to an outer diameter of the outer roller 4 and an operation requirement, which is not limited in this embodiment. The hollow microneedle groups are composed of the same preset number of hollow microneedles, and likewise, the number of hollow microneedles 5 of the same hollow microneedle group can be specifically determined according to the width of the outer roller 4 and the application requirements, which is not limited in this embodiment. The hollow microneedles 5 belonging to a hollow microneedle group are on the same plane so that the hollow microneedles 5 of the same hollow microneedle group can act on the skin simultaneously during the procedure.
The microneedle roller further comprises a mandrel member 6, one end or two ends of the mandrel member 6 are fixedly connected with the control handle 3, a supporting portion 7 which is matched with the inner wall surface of the outer roller 4 and supports the outer roller 4 is formed in the middle of the mandrel member 6, and the outer roller 4 can rotate relative to the supporting portion 7. The support 7 is further formed with a predetermined number of sub-liquid channels 8, i.e. the number of sub-liquid channels 8 is the same as the number of hollow microneedles 5 in a hollow microneedle set. When each hollow microneedle group rotates to a set position, the internal channels of the hollow microneedles 5 are respectively communicated with the corresponding sub-liquid channels 8.
Preferably, an annular sealing member 9, such as an annular polyurethane sealing member, is disposed at the outer periphery of the liquid outlet of each of the sub liquid passages 8, for preventing leakage of the liquid from the gap between the outer drum 4 and the supporting portion 7. Each of the annular seals 9 may be fitted in a fitting groove formed by recessing the outer peripheral wall surface of the support portion 7 at the outer periphery of the liquid outlet of the corresponding sub-liquid passage 8.
The spindle part 6 is also provided with a main liquid channel 10 communicated with each sub-liquid channel 8, and after reaching the main liquid channel 10, liquid enters each sub-liquid channel 8 and finally enters the human body through the internal channel of the corresponding hollow microneedle 5, so that the delivery of medicines or functional components is realized. The liquid inlet of the main liquid channel 10 may be arranged at the end of the spindle member 6 extending out of the operating handle 3, see fig. 2, i.e. the liquid inlet of the main liquid channel 10 is arranged at the right end of the spindle member 6.
Returning now to fig. 1, the outer delivery conduit 1 is used to direct the flow of a liquid containing a pharmaceutical and/or functional ingredient from a liquid supply 11 to the inlet of the main liquid channel 10, for example, to direct the flow of a liquid containing one or more of licoflavone, MT metallothionein, tranexamic acid from a liquid supply 11 to the inlet of the main liquid channel 10. In one embodiment, the applicator for microneedle surgery may further include a liquid supply 11, and the liquid supply 11 may be a container loaded with a liquid containing a drug and/or an active ingredient.
The fluid driving mechanism 2 is used for promoting the liquid of the liquid supply source 11 to flow to the liquid inlet of the main liquid channel 10 through the outer conveying pipeline 1, and the fluid driving mechanism 2 can be a pump, and can be arranged on the outer conveying pipeline 1 or can be arranged at the liquid inlet end of the outer conveying pipeline 1.
The outer conveying pipeline 1 comprises an elastic pipeline 12, wherein the elastic pipeline 12 is used for storing energy by deformation in the process that the fluid driving mechanism 2 drives the liquid to flow and two adjacent hollow microneedle groups rotate to the set position in sequence, and recovering the shape to release energy when the latter hollow microneedle group rotates to the set position, so that the liquid enters a human body in a pulse mode in the process of operation, the injection efficiency is high, and the problem that the hollow microneedle is easy to block can be solved. The outer conveying pipeline 1 can be composed of elastic pipelines 12 entirely, or a certain section of the outer conveying pipeline is the elastic pipeline 12. Preferably, the elastic pipe 12 is a silicone elastic pipe 12.
In one embodiment, the microneedle roller further comprises two end caps 13, and the two end caps 13 are respectively disposed at two end sides of the outer roller 4 and fixedly connected with the mandrel member 6, so as to restrict the movement of the outer roller 4 in the axial direction.
In one embodiment, the surgical device for microneedle surgery further comprises a control circuit 14, and the control circuit 14 may be a single-chip microcomputer. The control circuit 14 is electrically connected to the fluid driving mechanism 2, and is used for controlling the output power of the fluid driving mechanism 2, so as to adjust the injection amount of the liquid in the process of operation.
In this embodiment, the elastic tube 12 is utilized to store energy by deforming the fluid driving mechanism 2 in the process of forcing the fluid to flow and the two adjacent hollow microneedle groups rotate to the set position in sequence, and to recover the shape to release energy when the latter hollow microneedle group rotates to the set position, so that the fluid enters the human body in a pulse manner in the process of applying the liquid, the injection efficiency is high, and the problem that the hollow microneedle is easy to be blocked can be solved.
Claims (7)
1. An applicator for microneedle surgery, comprising:
the roller type microneedle comprises a microneedle roller and a control handle; the microneedle roller comprises an outer roller, wherein the peripheral wall of the outer roller is provided with a plurality of hollow microneedle groups which are radially distributed by taking the central shaft of the outer roller as the center, each hollow microneedle group consists of hollow microneedles with the same preset number, and the hollow microneedles belonging to one hollow microneedle group are positioned on the same plane; the microneedle roller also comprises a mandrel piece, at least one end of the mandrel piece is fixedly connected with the control handle, and a supporting part which is matched with the inner wall surface of the outer roller and supports the outer roller is formed in the middle of the mandrel piece; the supporting part is provided with a preset number of sub-liquid channels, and when each hollow microneedle group rotates to a set position, the internal channels of the hollow microneedles are respectively communicated with the corresponding sub-liquid channels; the spindle part is also provided with a main liquid channel communicated with each sub liquid channel;
an outer delivery conduit for directing a flow of a liquid containing a drug and/or an efficacious component from a liquid supply to a liquid inlet of the main liquid channel;
a fluid drive mechanism for causing liquid from the liquid supply to flow through the outer delivery conduit to the liquid inlet of the main liquid channel;
the outer conveying pipeline comprises an elastic pipeline, wherein the elastic pipeline is used for storing energy by deformation in the process that the fluid driving mechanism drives the liquid to flow and two adjacent hollow microneedle groups rotate to the set position in sequence, and recovering the shape to release energy when the latter hollow microneedle group rotates to the set position.
2. The applicator device for microneedle surgery of claim 1, wherein: the fluid drive mechanism is a pump.
3. The applicator device for microneedle surgery of claim 1, wherein: the elastic pipeline is a silica gel elastic pipeline.
4. The applicator device for microneedle surgery of claim 1, wherein: and annular sealing elements are arranged on the peripheries of the liquid outlets of the sub-liquid channels and are used for preventing leakage of liquid in gaps between the outer roller and the supporting parts.
5. The applicator for microneedle surgery of claim 4, wherein: the annular sealing element is an annular polyurethane sealing element.
6. An applicator for microneedle surgery according to any one of claims 1 to 5, wherein: the microneedle roller further comprises two end covers, wherein the two end covers are respectively arranged at two end sides of the outer roller and fixedly connected with the mandrel piece, and are used for restraining the outer roller from moving in the axial direction.
7. An applicator for microneedle surgery according to any one of claims 1 to 5, wherein: the control circuit is electrically connected with the fluid driving mechanism and used for controlling the output power of the fluid driving mechanism.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310440087.3A CN116370813A (en) | 2023-04-21 | 2023-04-21 | A apply art device for microneedle operation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310440087.3A CN116370813A (en) | 2023-04-21 | 2023-04-21 | A apply art device for microneedle operation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116370813A true CN116370813A (en) | 2023-07-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310440087.3A Pending CN116370813A (en) | 2023-04-21 | 2023-04-21 | A apply art device for microneedle operation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116370813A (en) |
-
2023
- 2023-04-21 CN CN202310440087.3A patent/CN116370813A/en active Pending
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