CN116324564A - 用人工智能进行自动聚焦和自动化细胞计数的系统和方法 - Google Patents

用人工智能进行自动聚焦和自动化细胞计数的系统和方法 Download PDF

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CN116324564A
CN116324564A CN202180064586.6A CN202180064586A CN116324564A CN 116324564 A CN116324564 A CN 116324564A CN 202180064586 A CN202180064586 A CN 202180064586A CN 116324564 A CN116324564 A CN 116324564A
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cell
neural network
tiles
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N·罗格宁
L·莱斯壮
O·格卢布
J·保林
N·迪利亚尼
K·伊波利托
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Cellomics Inc
Life Technologies Corp
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Life Technologies Corp
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    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
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    • G02B7/28—Systems for automatic generation of focusing signals
    • G02B7/36—Systems for automatic generation of focusing signals using image sharpness techniques, e.g. image processing techniques for generating autofocus signals
    • G02B7/38—Systems for automatic generation of focusing signals using image sharpness techniques, e.g. image processing techniques for generating autofocus signals measured at different points on the optical axis, e.g. focussing on two or more planes and comparing image data
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    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N15/10—Investigating individual particles
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    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison

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  • Image Processing (AREA)
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  • Automatic Focus Adjustment (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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CN202180064586.6A 2020-10-16 2021-10-14 用人工智能进行自动聚焦和自动化细胞计数的系统和方法 Pending CN116324564A (zh)

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US202063092783P 2020-10-16 2020-10-16
US63/092,783 2020-10-16
US202163254338P 2021-10-11 2021-10-11
US63/254,338 2021-10-11
PCT/US2021/055008 WO2022081863A2 (en) 2020-10-16 2021-10-14 Systems and methods for autofocus and automated cell count using artificial intelligence

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