CN116323556B - 抗微生物和抗病毒的含硫甘油单酯衍生物 - Google Patents

抗微生物和抗病毒的含硫甘油单酯衍生物

Info

Publication number
CN116323556B
CN116323556B CN202180067019.6A CN202180067019A CN116323556B CN 116323556 B CN116323556 B CN 116323556B CN 202180067019 A CN202180067019 A CN 202180067019A CN 116323556 B CN116323556 B CN 116323556B
Authority
CN
China
Prior art keywords
day
compound
infection
compounds
present disclosure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202180067019.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN116323556A (zh
Inventor
戴顿·T·瑞尔丹
保罗·布伦南
帕特里克·施利韦尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nicky Biopharmaceutical Co ltd
Original Assignee
Nicky Biopharmaceutical Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicky Biopharmaceutical Co ltd filed Critical Nicky Biopharmaceutical Co ltd
Publication of CN116323556A publication Critical patent/CN116323556A/zh
Application granted granted Critical
Publication of CN116323556B publication Critical patent/CN116323556B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/02—Monothiocarboxylic acids
    • C07C327/04—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C327/06—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/36—Esters of dithiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN202180067019.6A 2020-09-18 2021-09-17 抗微生物和抗病毒的含硫甘油单酯衍生物 Active CN116323556B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/948,453 2020-09-18
US16/948,453 US11572342B2 (en) 2020-09-18 2020-09-18 Antimicrobial and antiviral sulfur containing glycerol monoester derivatives
PCT/US2021/071500 WO2022061365A1 (en) 2020-09-18 2021-09-17 Antimicrobial and antiviral sulfur containing glycerol monoester derivatives

Publications (2)

Publication Number Publication Date
CN116323556A CN116323556A (zh) 2023-06-23
CN116323556B true CN116323556B (zh) 2026-04-03

Family

ID=80739431

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180067019.6A Active CN116323556B (zh) 2020-09-18 2021-09-17 抗微生物和抗病毒的含硫甘油单酯衍生物

Country Status (5)

Country Link
US (3) US11572342B2 (https=)
EP (1) EP4214191A4 (https=)
JP (1) JP7820832B2 (https=)
CN (1) CN116323556B (https=)
WO (1) WO2022061365A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11572342B2 (en) 2020-09-18 2023-02-07 Niche Biopharmaceuticals LLC Antimicrobial and antiviral sulfur containing glycerol monoester derivatives

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208257A (en) 1986-04-21 1993-05-04 Kabara Jon J Topical antimicrobial pharmaceutical compositions and methods
US4746515A (en) 1987-02-26 1988-05-24 Alza Corporation Skin permeation enhancer compositions using glycerol monolaurate
JP3507486B2 (ja) 1991-03-15 2004-03-15 アムジエン・インコーポレーテツド 顆粒球コロニー刺激因子の肺内投与
US5256405A (en) 1991-12-30 1993-10-26 Tom's Of Maine Herbal deodorant
US5451569A (en) 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
US5569461A (en) 1995-02-07 1996-10-29 Minnesota Mining And Manufacturing Company Topical antimicrobial composition and method
US5906814A (en) 1995-12-07 1999-05-25 The Andrew Jergens Company Topical film-forming compositions
DE69739583D1 (de) 1996-11-14 2009-10-29 Lipomedica Ehf Topische zusammensetzungen enthaltend als therapeutisch aktiven wirkstoff ein monoglycerid zur behandlung von schleimhautinfektionen
US20050058673A1 (en) 2003-09-09 2005-03-17 3M Innovative Properties Company Antimicrobial compositions and methods
US8796332B2 (en) 2004-08-03 2014-08-05 Regents Of The University Of Minnesota Compositions and methods for controlling infections
WO2006087681A2 (en) * 2005-02-17 2006-08-24 Koninklijke Philips Electronics N.V. Fluid optical waveguide
WO2006099325A2 (en) * 2005-03-10 2006-09-21 3M Innovative Properties Company Methods of treating ear infections
BR112012006107A2 (pt) 2009-09-17 2016-06-07 Eugene B Guthery formulações nasais, de ferida e de pele e métodos para controle de staphylococci e outras bactérias gram-positivas resistentes a antibiótico
HK1205696A1 (en) * 2012-04-20 2015-12-24 亨内平生命科学公司 Compositions for topical treatment of microbial infections
WO2019079150A1 (en) * 2017-10-18 2019-04-25 Hennepin Life Sciences, Llc COMPOSITIONS AND METHODS FOR TREATING ATOPIC DERMATITIS
US11572342B2 (en) * 2020-09-18 2023-02-07 Niche Biopharmaceuticals LLC Antimicrobial and antiviral sulfur containing glycerol monoester derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CAS RN. 74942-95-3 等;CA 公司;STN REGISTRY数据库;20151206;1 *

Also Published As

Publication number Publication date
US11873272B2 (en) 2024-01-16
EP4214191A4 (en) 2024-10-30
WO2022061365A1 (en) 2022-03-24
US11365176B2 (en) 2022-06-21
JP2023543442A (ja) 2023-10-16
JP7820832B2 (ja) 2026-02-26
US11572342B2 (en) 2023-02-07
CN116323556A (zh) 2023-06-23
EP4214191A1 (en) 2023-07-26
US20230174473A1 (en) 2023-06-08
US20220127224A1 (en) 2022-04-28
US20220089535A1 (en) 2022-03-24

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