CN116263462A - Control method of test flow, sample analyzer, electronic device and storage medium - Google Patents
Control method of test flow, sample analyzer, electronic device and storage medium Download PDFInfo
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
- G01N21/763—Bioluminescence
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N2021/0106—General arrangement of respective parts
- G01N2021/0112—Apparatus in one mechanical, optical or electronic block
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N2021/0162—Arrangements or apparatus for facilitating the optical investigation using microprocessors for control of a sequence of operations, e.g. test, powering, switching, processing
- G01N2021/0168—Arrangements or apparatus for facilitating the optical investigation using microprocessors for control of a sequence of operations, e.g. test, powering, switching, processing for the measurement cycle
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0439—Rotary sample carriers, i.e. carousels
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0439—Rotary sample carriers, i.e. carousels
- G01N2035/0444—Rotary sample carriers, i.e. carousels for cuvettes or reaction vessels
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Abstract
The application discloses a control method of a test flow, a sample analyzer, electronic equipment and a readable storage medium. The test flow comprises a plurality of test periods, each test period comprises M moving subcycles and N static subcycles, the moving subcycles and the static subcycles are arranged at intervals, and at least one of the static subcycles corresponds to an operation position, and the method comprises the following steps: receiving a first test procedure for a first reaction cup; confirming a test action period in a plurality of test periods of the first test flow; after the first reaction cup enters the test action period, controlling the first reaction cup to move to or from a target operation position corresponding to a static sub-period adjacent to the moving sub-period in the moving sub-period of the test action period; during the rest sub-period, a test operation is performed on the first cuvette at the target operation position. According to the method and the device, the test items with different durations can be realized on the premise of fixing the main period, the volume of the instrument can be reduced, and the cost of the instrument is saved.
Description
Technical Field
The present disclosure relates to the field of medical technologies, and in particular, to a control method for a test procedure, a sample analyzer, an electronic device, and a storage medium.
Background
Sample analyzers (e.g., chemiluminescent analyzers, etc.) may be used to detect specific markers in bodily fluids (e.g., blood, etc.). Each instrument can be used to test a variety of markers based on a testing methodology. Due to the different identifiers and the different time requirements of the user side, the sample analyzer needs to be provided with a plurality of detection flows as much as possible.
However, due to different time requirements between different detection flows, it is difficult for the sample analyzer to simultaneously consider multiple detection flows with different times, and detection conflicts may be caused in the actual detection process. To solve this problem, it is common practice to provide different reaction vessel buffer areas for different moving parts, for example, to provide a sample loading area corresponding to a sample loading arm, to provide an oscillation mixing area, and so on. However, this approach also results in a larger instrument volume, requiring a larger installation and operating area on the part of the user.
Disclosure of Invention
The embodiment of the application provides a control method of a test flow, a sample analyzer, electronic equipment and a storage medium, so as to solve the problems that in the related art, different buffer areas of a reaction container are set for different moving parts, so that a larger instrument volume is caused, and a larger installation and operation area is required.
In order to solve the above technical problems, embodiments of the present application are implemented as follows:
in a first aspect, an embodiment of the present application provides a control method for controlling a sample testing process of a sample analyzer, where the testing process includes a plurality of testing periods, each testing period includes M moving sub-periods and N stationary sub-periods, the moving sub-periods and the stationary sub-periods are set at intervals, at least one of the stationary sub-periods corresponds to an operation position, and M and N are both positive integers, and the method includes:
receiving a first test procedure for a first reaction cup;
confirming a test action cycle of the plurality of test cycles of the first test flow;
after a first reaction cup enters a test action period, controlling the first reaction cup to move to or from a target operation position corresponding to a static subcycle adjacent to the moving subcycle in the moving subcycle;
and in the rest subcycle, performing a test operation on the first reaction cup at the target operation position.
In this application, the sample analyzer concerned uses a rotating turntable to perform the test tasks. The number of the turntables may be one or two. In this case, a rotary disk is used as an example, which simultaneously serves as an incubation disk. A plurality of handling means, such as a cuvette handling device, a loading arm, a detection unit, a reagent loading arm, etc., are arranged around the turntable. The rotary disk is provided with a reaction cup groove along the circumference. The reaction cup is placed in the reaction cup groove and is fixed in position relative to the turntable. The reaction cup is moved to different operation devices through the rotation of the turntable.
The test task is a test item to be executed for a sample to be tested, which is obtained by the sample analyzer. In this application, a test task consists of a number of fixed test cycles. The test cycle is the period during which the carousel loads the reaction cups, i.e., the period of time the carousel takes between loading two reaction cups. In the application, the action of loading the reaction cup by the rotary table is taken as a mark for starting a first test period of a test task. When the test tasks are consecutive in sequence, each test task is executed in units of test periods. That is, the same operating device starts one test cycle of the second test task after one test cycle of the first test task is performed. Thus, the fixed-position operating device can execute the corresponding action of the second test task in the next test period after finishing the operation of the first test task in the current test period, and does not need to wait for the first test task to finish completely and execute the second test task. During each test cycle, the cuvette is transported to a different handling device position by movement of the turntable.
The number of test cycles is determined according to the type of item to be detected, so that the duration of the total test cycle can be determined according to the item to be detected. For example, an HIV detection task contains 65 test cycles, while an myocarditis detection task contains 45 test cycles. Among a plurality of test cycles of the test task, a test action cycle is divided. The test action cycle is a test cycle in which the operation device performs a test operation on the reaction cup, such as moving the reaction cup, adding a test sample, a test reagent, and the like into the reaction cup.
Optionally, the performing a test operation on the first reaction cup at the target operation position during the rest sub-period includes:
receiving a first test signal for a target device at the target operating location;
and in the rest subcycle, calling an operation device corresponding to the target operation position to execute test operation on the first reaction cup.
Optionally, receiving a second test procedure for testing a second cuvette that is sequentially located after the first cuvette;
confirming a test action cycle of the plurality of test cycles of the second test flow;
and after the test action cycle is executed on the first reaction cup, controlling the second reaction cup to enter the test action cycle.
Optionally, the movement paths of the first reaction cup and the second reaction cup in each test period are the same.
Optionally, after said controlling said second cuvette to enter said test action cycle, further comprising:
receiving a second test signal for a target device at the target operating location;
and after the second reaction cup enters the static subcycle, calling an operation device corresponding to the target operation position to execute test operation on the second reaction cup.
Optionally, when the test items of the first reaction cup and the second reaction cup are different, the test duration of the first reaction cup and the second reaction cup in the same rest subcycle is the same; or alternatively
When the test items of the first reaction cup and the second reaction cup are the same, the test time lengths of the first reaction cup and the second reaction cup in the same static subcycle are different.
In a second aspect, an embodiment of the present application provides a sample analyzer for controlling a sample testing process, where the testing process includes a plurality of testing periods, each testing period includes M moving sub-periods and N stationary sub-periods, the moving sub-periods and the stationary sub-periods are spaced apart, at least one of the stationary sub-periods corresponds to an operation position, and M and N are both positive integers, the analyzer includes: a host machine, a plurality of operating devices are arranged on the host machine; a carrying mechanism; a controller;
wherein:
the controller is used for receiving a first test flow for the first reaction cup; confirming a test action cycle of the plurality of test cycles of the first test flow;
the bearing mechanism is used for driving the first reaction cup to move to or from a target operation position corresponding to a static subcycle adjacent to the moving subcycle in the moving subcycle after the first reaction cup enters the testing action cycle;
The operating means is for performing a test operation on the first cuvette at the target operating position during the stationary sub-period.
Optionally, the controller is configured to generate a first test signal of a target device at the target operation location according to the first test procedure, and send the first test signal to the target device;
the operating device is used for executing test operation on the first reaction cup in the stationary subcycle.
Optionally, the carrying mechanism is configured to, after the test action cycle is executed on the first reaction cup, drive a second reaction cup, which is located after the first reaction cup in a test sequence, to enter the test action cycle.
Optionally, the movement paths of the first reaction cup and the second reaction cup in the test action cycle are the same.
Optionally, the controller is configured to generate a second test signal of the target device at the target operation location according to the second test procedure, and send the second test signal to the target device;
the operating device is used for executing test operation on the second reaction cup after the second reaction cup enters the static subcycle.
Optionally, when the test items of the first reaction cup and the second reaction cup are different, the test duration of the first reaction cup and the second reaction cup in the same rest subcycle is the same; or alternatively
When the test items of the first reaction cup and the second reaction cup are the same, the test time lengths of the first reaction cup and the second reaction cup in the same static subcycle are different.
In a third aspect, an embodiment of the present application provides an electronic device, including: the test flow control device comprises a memory, a processor and a computer program stored in the memory and capable of running on the processor, wherein the computer program realizes the control method of any one of the test flows when being executed by the processor.
In a fourth aspect, embodiments of the present application provide a readable storage medium, which when executed by a processor of an electronic device, enables the electronic device to perform a control method of a test procedure as described in any one of the above.
Accordingly, the present application also relates to a sample analyzer having the above readable storage medium. The sample analyzer may be a chemiluminescent analyzer. In one embodiment, the sample analyzer may be a photoexcitation chemiluminescent analyzer.
The chemiluminescent analyzer of the present application comprises a support mechanism. Each handling means is arranged around the carrier for handling the reaction cup. In addition, the carrying mechanism simultaneously plays a role of an incubation plate. The cuvette may thus undergo a complete chemiluminescent reaction test procedure on the support means from the moment it enters the support means to the moment it leaves the support means.
Specifically, the carrier mechanism receives cuvettes from one cuvette conveyor and transfers the cuvette to each manipulator, e.g. sample arm, dilution arm, reagent arm, emergency reagent arm, optical detection mechanism, according to the test cycle. Meanwhile, in a test cycle of a test procedure, which does not require operation of the reaction cup, the reaction cup can be incubated on the bearing mechanism. Thus, although the test procedures may be different, the test procedures of different test items can still be completed on one carrying mechanism by means of the test period setting of the present application.
In the embodiment of the application, a fixed test period is divided into a plurality of moving subcycles and stationary subcycles, wherein test operations (such as sample adding, reagent adding, reading and the like) of the reaction cup at a plurality of operation positions can be realized in the stationary subcycle. Because a plurality of moving periods and a plurality of different operating positions are set, the reaction cup can be moved to the plurality of operating positions in one test period on the premise of fixing the main period, so that the reaction cup is matched with a plurality of test items with different durations, and different reaction container buffer areas are not required to be set for different moving parts. Therefore, the volume of the instrument can be reduced, and the cost of the instrument can be saved.
The foregoing description is only an overview of the technical solutions of the present application, and may be implemented according to the content of the specification in order to make the technical means of the present application more clearly understood, and in order to make the above-mentioned and other objects, features and advantages of the present application more clearly understood, the following detailed description of the present application will be given.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the description of the embodiments of the present application will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person of ordinary skill in the art.
Fig. 1 is a step flowchart of a control method of a test flow provided in an embodiment of the present application;
FIG. 2 is a flowchart illustrating steps of another method for controlling a test flow according to an embodiment of the present application;
fig. 3 is a schematic view of a carrying mechanism according to an embodiment of the present application;
fig. 4 is a schematic structural diagram of a sample analyzer for controlling a sample testing procedure according to an embodiment of the present application.
Detailed Description
The following description of the embodiments of the present application will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are some, but not all, of the embodiments of the present application. All other embodiments, which can be made by one of ordinary skill in the art based on the embodiments herein without making any inventive effort, are intended to be within the scope of the present application.
The embodiment of the application can be applied to in-vitro diagnostic equipment, in particular to a chemiluminescent analyzer, and more preferably a photoexcited chemiluminescent analyzer. Embodiments of the present application are preferably used in an in vitro diagnostic device having an automated test function (e.g., loading, testing agent, etc.). Particularly in the detection assembly line formed by a plurality of in-vitro diagnosis devices, the embodiment of the application can realize the automatic control of the reaction cup, thereby avoiding the time conflict of the reaction cup.
Example 1
Referring to fig. 1, a step flowchart of a control method of a test flow provided in an embodiment of the present application is shown, where the method may be used to control a sample test flow of a sample analyzer, the test flow may include a plurality of test periods, each test period includes M moving subcycles and N stationary subcycles, where the moving subcycles and the stationary subcycles are set at intervals, at least one of the stationary subcycles corresponds to an operation position, and M and N are both positive integers, as shown in fig. 1, and the control method of the test flow may include the following steps:
Step 101: a first test procedure for a first cuvette is received.
The test flow refers to the whole flow from loading of the cuvette by the analytical instrument to the discharge of the waste cuvette by the test completion.
The present embodiment can be applied to a sample testing flow for controlling a sample analyzer.
In this example, each test period may be divided into M moving sub-periods and N stationary sub-periods in advance, M and N being positive integers. Wherein the moving sub-period and the stationary sub-period are arranged at intervals, and at least one of the N stationary sub-periods corresponds to an operation position, at which a test operation (such as sample addition, reagent addition, etc.) can be performed on the reaction cup.
In this embodiment, the sample analyzer has an incubation plate. The operating positions may be located along the circumference of an incubation plate (fig. 3) of the sample analyzer. The operating means is arranged around the incubation plate at a position corresponding to the operating position for operating the reaction cup. In this application, the operations of adding sample, adding reagent, detecting, discarding the cup, etc. are completed from the time the cuvette is loaded onto the incubation tray to the time it is discharged from the incubation tray. Furthermore, the cuvette is always at the incubation temperature via the incubation tray from the loading of the cuvette onto the incubation tray. So that the reaction cup can complete all test steps required by the photo-activated chemiluminescence analysis on one incubation plate.
The first test procedure refers to a procedure of executing a test task on the first reaction cup.
After the sample analyzer is put into operation, a first test procedure for the first cuvette may be received.
After receiving the first test procedure for the first cuvette, step 102 is performed.
Step 102: and confirming a test action period in the plurality of test periods of the first test flow.
A plurality of test cycles may be included in the first test procedure of the first cuvette. The number of test periods is determined according to the type of the item to be detected, so that the duration of the total test period may be determined according to the item to be detected, which is not limited in this embodiment. For example, an HIV test item contains 65 test cycles, while an myocarditis test item contains 45 test cycles.
In this example, the test period is divided into test action periods. The test action cycle is a test cycle in which a test operation is performed on the cuvette, such as a test sample, a test reagent, or the like is added to the cuvette by moving the cuvette. For example, the 65 test cycles of an HIV test program may be divided into 20 test cycles, while the remaining 45 test cycles are performed without any manipulation of the cuvette on the incubation tray, so that the cuvette may be incubated on the incubation tray during these 45 cycles.
After receiving the first test procedure for the first reaction cup, a test action cycle of the plurality of test cycles of the first test procedure may be confirmed.
After confirming the test action cycle of the plurality of test cycles of the first test flow, step 103 is performed.
Step 103: after the first reaction cup enters the testing action period, the first reaction cup is controlled to move to or out of a target operation position corresponding to a static subcycle adjacent to the moving subcycle in the testing action period.
The target operating position refers to an operating position corresponding to a stationary sub-period adjacent to a moving sub-period in which the first cuvette is currently located.
After confirming the test action cycle in the multiple test cycles of the first test flow, and after the first reaction cup enters the test action cycle, the first reaction cup can be controlled to move to or from a target operation position corresponding to a stationary sub-cycle adjacent to the moving sub-cycle in the moving sub-cycle of the test action cycle. Specifically, when the first cuvette is moved from the movement sub-cycle to the target operation position, the first cuvette may be controlled to move to the target operation position by the analyzer in the movement sub-cycle. And when the first reaction cup enters the moving sub-period from the static sub-period, the analyzer can control the first reaction cup to move out of the target operation position corresponding to the static sub-period.
Step 104: and in the rest subcycle, performing a test operation on the first reaction cup at the target operation position.
After the first cuvette is moved to the stationary sub-cycle, a test operation, such as loading, loading reagents, reading, etc., may be performed on the first cuvette at a target operation position corresponding to the stationary sub-cycle.
If the set test action period includes 5 moving sub-periods and 4 stationary sub-periods, the 5 moving sub-periods are respectively: period 1, period 2, period 3, period 4, and period, the 4 stationary subcycles are respectively: the arrangement sequence (from first to last) of the 9 sub-periods is as follows: period 1, period a, period 2, period b, period 3, period c, period 4, period d, period 5.
Firstly, after the first reaction cup enters a test action period, the first reaction cup can be controlled to move through an analyzer in the period 1 so as to move to an operation position corresponding to the period a, and corresponding test operation is carried out on the first reaction cup at the operation position. Secondly, when the time condition corresponding to the period a is reached, the analyzer controls the first reaction cup to move out of the operation position, move to the operation position corresponding to the period b in the period 2, and execute corresponding test operation on the first reaction cup at the operation position. Then, when the time condition corresponding to the period b is reached, the analyzer controls the first reaction cup to move out of the operation position, and the first reaction cup moves to the operation position corresponding to the period c in the period 3, and the corresponding test operation is executed on the first reaction cup at the operation position corresponding to the period c. And when the time condition corresponding to the period c is reached, controlling the first reaction cup to move out of the operation position corresponding to the period c through the analyzer, moving to the operation position corresponding to the period d in the period 3, and executing corresponding test operation on the first reaction cup at the operation position corresponding to the period d. Further, when the time condition corresponding to the period d is reached, the analyzer controls the first reaction cup to move out of the operation position corresponding to the period d, and moves to the next test period in the period 5.
It will be appreciated that the above examples are only examples listed for better understanding of the technical solutions of the embodiments of the present application, and are not to be construed as the only limitation of the present embodiments.
In the whole test flow of the test action cycle of the first reaction cup, the moving path of the first reaction cup in the test action cycle is equal to the sum of the moving sub-paths of the first reaction cup in M moving sub-cycles in the test action cycle, namely the first reaction cup is in a static state at the operation position corresponding to the static sub-cycle, and the test operation is only executed on the first reaction cup.
According to the embodiment of the application, the fixed test period is divided into the plurality of movable subcycles and the stationary subcycles, and the test operation of the reaction cup at a plurality of operation positions can be realized through the stationary subcycles, so that the problem of time conflict generated by different time-length test items can be avoided.
According to the control method of the test flow provided by the embodiment of the application, a fixed test period is divided into a plurality of moving subcycles and static subcycles, wherein test operations (such as sample adding, reagent adding, reading and the like) of the reaction cup at a plurality of operation positions can be realized in the static subcycle. Because a plurality of moving periods and a plurality of different operating positions are set, the reaction cup can be moved to the plurality of operating positions in one test period on the premise of fixing the main period, so that the reaction cup is matched with a plurality of test items with different durations, and different reaction container buffer areas are not required to be set for different moving parts. Therefore, the volume of the instrument can be reduced, and the cost of the instrument can be saved.
Example two
Referring to fig. 2, a step flow chart of another control method of a test flow provided in an embodiment of the present application is shown, where the method may be used to control a sample test flow of a sample analyzer, where the test flow may include a plurality of test periods, each test period includes M moving sub-periods and N stationary sub-periods, where at least one of the stationary sub-periods corresponds to an operation position, and M and N are both positive integers, and the control method of the test flow may include the following steps, as shown in fig. 2:
step 201: a first test procedure for a first cuvette is received.
The embodiment of the application can be applied to a scene of controlling the test flow of the reaction cup according to the moving subcycle and the static subcycle which are divided by the test cycle.
The test flow refers to the whole flow from the cup on the analytical instrument to the test completion of discarding the cup.
The present embodiment can be applied to a sample testing flow for controlling a sample analyzer.
In this example, each test period may be divided into M moving sub-periods and N stationary sub-periods in advance, M and N being positive integers. Wherein the moving sub-period and the stationary sub-period are arranged at intervals, and at least one of the N stationary sub-periods corresponds to an operation position, at which a test operation (such as sample addition, reagent addition, etc.) can be performed on the reaction cup.
The first test procedure refers to a procedure of executing a test task on the first reaction cup.
After the sample analyzer is put into operation, a first test procedure for the first cuvette may be received.
After receiving the first test procedure for the first cuvette, step 202 is performed.
Step 202: and confirming a test action period in the plurality of test periods of the first test flow.
The first test flow of the first reaction cup may include a plurality of test cycles, and the duration of each test cycle may depend on the type of the test sample in the reaction cup, which is not limited in this embodiment.
In this example, a test action cycle is included in the test cycle, and a test operation may be performed on the cuvette during the test cycle, such as an operation of moving the cuvette, adding a test sample, a test reagent, or the like into the cuvette.
After receiving the first test procedure for the first reaction cup, a test action cycle of the plurality of test cycles of the first test procedure may be confirmed.
After confirming the test action cycle of the plurality of test cycles of the first test flow, step 203 is performed.
Step 203: after the first reaction cup enters the testing action period, the first reaction cup is controlled to move to or out of a target operation position corresponding to a static subcycle adjacent to the moving subcycle in the testing action period.
The target operating position refers to an operating position corresponding to a stationary sub-period adjacent to a moving sub-period in which the first cuvette is currently located.
After confirming the test action cycle in the multiple test cycles of the first test flow, and after the first reaction cup enters the test action cycle, the first reaction cup can be controlled to move to or from a target operation position corresponding to a stationary sub-cycle adjacent to the moving sub-cycle in the moving sub-cycle of the test action cycle. Specifically, when the first cuvette is moved from the movement sub-cycle to the target operation position, the first cuvette may be controlled to move to the target operation position by the analyzer in the movement sub-cycle. And when the first reaction cup enters the moving sub-period from the static sub-period, the analyzer can control the first reaction cup to move out of the target operation position corresponding to the static sub-period.
Step 204: a first test signal is received for a target device at the target operational location.
The target device refers to an operating device at a target operating position, which in this example may be a loading needle. The operating device is connected with the controller. The controller may send a control signal, i.e. a test signal, to the operating device. The first test signal may be a signal for indicating that a test operation is performed on the first cuvette located at the target operation position. In a specific implementation, the controller may include: the upper computer can receive the test flow and send test tasks to the middle computer, and the middle computer can control the action of the operation equipment. After the upper computer receives the test flow of the reaction cup, the upper computer can send a test task for the reaction cup to the middle computer, and the middle computer generates control signals of all operation devices and sends the control signals to the operation devices after receiving the test task.
In this example, the controller may generate a first test signal for the target device at the target operating position according to the first test procedure of the first cuvette and transmit the first test signal to the target device.
When it is determined that the target device at the target operating position does not receive the first test signal, waiting may continue. If there is no first test signal for the rest sub-period, the reaction cup is left to stand until the next movement sub-period is entered to control the first reaction cup to move out of the target operation position, for example, for a reading operation at the target operation position, the reading is performed twice before, without a third reading, and when the reaction cup is moved to the target operation position for the third time, no test signal is received.
After receiving the first test signal for the target device at the target operating position, step 205 is performed.
Step 205: and in the rest subcycle, calling an operation device corresponding to the target operation position to execute test operation on the first reaction cup.
After receiving the first test signal for the target device at the target operation position, the operation device corresponding to the target operation position may be called to execute a test operation, such as a sample adding operation, a reagent adding operation, a reading operation, etc., on the first reaction cup after the first reaction cup enters a rest period.
The above process may be described in detail as follows in connection with fig. 3.
Referring to fig. 3, a schematic view of a carrying mechanism provided in an embodiment of the present application is shown, where the carrying mechanism simultaneously functions as an incubation tray. In this application, the handling means are arranged around the carrier means for handling the reaction cup. As shown in fig. 3, the carrying mechanism on the sample analyzer may include: the carrier 11, the loading station 101, the sample station 102, the reagent injection station 103, the detection station 104 and the unloading station 105, wherein the loading station 101, the sample station 102, the reagent injection station 103, the detection station 104 and the unloading station 105 are operation positions, and the carrier 11 can be driven by a power device such as a motor to move along a set path after the first reaction cup arrives at the loading station 101 and leaves the unloading station 105, for example, the motor directly drives the carrier 11 to rotate through a speed reducing mechanism, or the motor drives the carrier 11 to move along a straight line through a gear rack mechanism. At the loading station 101, the first cuvette is loaded onto the carrier 11, which, when the carrier 11 is moved, brings the first cuvette together until the first cuvette arrives at the unloading station 105 to be unloaded from the carrier. In the process, a loading operation, i.e. an operation performed during a first stationary sub-period, may be performed at the loading station 101, i.e. after receiving a test signal from the target device at the loading station 101, the first cuvette is loaded onto the carrier 11. After entering the first movement sub-period, the carrier 11 may drive the first cuvette to move to the sample station 102, and after the first cuvette moves to the sample station 102, in the second stationary sub-period, the sample arm at the sample station 102 may be invoked to add a test sample into the first cuvette according to the received test signal for the target device at the sample station 102. After entering the second moving sub-period, the carrier 11 may drive the first reaction cup to move to the reagent injection station 103, and after the first reaction cup moves to the reagent injection station 103, in the third stationary sub-period, according to the received test signal for the target device at the reagent injection station 103, the reagent arm corresponding to the reagent injection station 103 may be called to add the test reagent into the first reaction cup. After entering the third movement sub-period, the carrier 11 may drive the first reaction cup to move to the detection station 104, and after the first reaction cup moves to the detection station 104, in the fourth stationary sub-period, according to the received test signal for the target device at the detection station 104, the operation device corresponding to the detection station 104 may be invoked to detect the chemiluminescent signal in the first reaction cup. After entering the fourth moving sub-period, the carrier 11 may drive the first reaction cup to move to the unloading station 105, and after the first reaction cup moves to the unloading station 105, in the fifth stationary sub-period, according to the received test signal for the target device at the unloading station 105, the operation device corresponding to the unloading station 105 may be invoked to realize separation of the first reaction cup and the carrier mechanism.
It will be appreciated that the above examples are only examples listed for better understanding of the technical solutions of the embodiments of the present application, and are not to be construed as the only limitation of the present embodiments.
Step 206: a second test procedure is received for testing a second cuvette that is sequentially positioned after the first cuvette.
The second test procedure refers to a procedure of executing a test task on the second reaction cup.
During the execution of the test tasks on the first cuvette, a second test procedure for testing a second cuvette that is sequentially positioned after the first cuvette may also be received.
After receiving a second test procedure for testing a second cuvette, which is sequentially located after the first cuvette, step 207 is performed.
Step 207: and confirming a test action period in the plurality of test periods of the second test flow.
After receiving a second test procedure for testing a second cuvette that is sequentially positioned after the first cuvette, a test action cycle of a plurality of test cycles of the second test procedure may be confirmed.
After confirming the test action cycle of the plurality of test cycles of the second test flow, step 208 is performed.
Step 208: and after the test action cycle is executed on the first reaction cup, controlling the second reaction cup to enter the test action cycle.
After confirming the test action cycle in the multiple test cycles of the second test flow, the second reaction cup can be controlled to enter the test action cycle after the test action cycle is executed on the first reaction cup, namely, after one reaction cup is executed for one test action cycle, the next reaction cup is controlled to enter the test action cycle, so that the uninterrupted test flow of the reaction cups is realized, and the test efficiency is improved.
After controlling the second cuvette to enter the test action cycle, step 209 is performed.
Step 209: a second test signal is received for a target device at the target operational location.
After controlling the second cuvette to enter the test action cycle, a second test signal for the target device at the target operating position may be received.
If a second test signal is received for a target device at a target operating location, step 210 is performed.
Step 210: and after the second reaction cup enters the static subcycle, calling an operation device corresponding to the target operation position to execute test operation on the second reaction cup.
After receiving the second test signal for the target device at the target operation position, the operation device corresponding to the target operation position may be called to execute the test operation on the second reaction cup after the second reaction cup enters the rest sub-period.
In this example, the movement paths of the first cuvette and the second cuvette are identical in each test period.
When the test items of the first reaction cup and the second reaction cup are different, the test time periods of the first reaction cup and the second reaction cup in the same static subcycle are the same. Of course, when the test items of the first reaction cup and the second reaction cup are different, the test time periods of the first reaction cup and the second reaction cup in the same static subcycle may also be different.
When the test items of the first reaction cup and the second reaction cup are the same, the test periods of the first reaction cup and the second reaction cup in the same static sub-period are different, and of course, may be the same, specifically, may be determined according to the service requirement, which is not limited in this embodiment.
According to the control method of the test flow provided by the embodiment of the application, a fixed test period is divided into a plurality of moving subcycles and static subcycles, wherein test operations (such as sample adding, reagent adding, reading and the like) of the reaction cup at a plurality of operation positions can be realized in the static subcycle. Because a plurality of moving periods and a plurality of different operating positions are set, the reaction cup can be moved to the plurality of operating positions in one test period on the premise of fixing the main period, so that the reaction cup is matched with a plurality of test items with different durations, and different reaction container buffer areas are not required to be set for different moving parts. Therefore, the volume of the instrument can be reduced, and the cost of the instrument can be saved.
Example III
Referring to fig. 4, there is shown a sample analyzer for controlling a sample testing process provided in an embodiment of the present application, the testing process including a plurality of testing periods, each of the testing periods including M moving sub-periods and N stationary sub-periods, the moving sub-periods and the stationary sub-periods being spaced apart, wherein at least one of the stationary sub-periods corresponds to an operation position, and M and N are both positive integers, the analyzer 400 includes: a host 410 on which a plurality of operating devices 420 are provided; a carrying mechanism 430; a controller 440;
wherein:
the controller 440 is configured to receive a first test procedure for a first cuvette; confirming a test action cycle of the plurality of test cycles of the first test flow;
the carrying mechanism 430 is configured to drive, after the first reaction cup enters the test action cycle, the first reaction cup to move to or from a target operation position corresponding to a stationary sub-cycle adjacent to the moving sub-cycle in the moving sub-cycle of the test action cycle;
the operation means 420 is for performing a test operation on the first cuvette at the target operation position during the rest sub-period.
Optionally, the controller 440 is configured to generate a first test signal of a target device at the target operation location according to the first test procedure, and send the first test signal to the target device;
the operation device 420 is configured to perform a test operation on the first reaction cup during the rest sub-period.
In this embodiment, the controller may generate all the first test signals required in the first test flow at one time, that is, generate all the first test signals for all the target devices at one time. The controller transmits the first test signal to each of the operation devices so that each of the operation devices operates at a predetermined time.
Optionally, the carrying mechanism 430 is configured to, after the test action cycle is performed on the first reaction cup, drive a second reaction cup, which is located after the first reaction cup in the test action cycle in a test sequence.
Optionally, the movement paths of the first reaction cup and the second reaction cup in the test action cycle are the same.
Optionally, the controller 440 is configured to generate a second test signal of the target device at the target operation location according to the second test procedure, and send the second test signal to the target device;
The operation device 420 is configured to perform a test operation on the second reaction cup after the second reaction cup enters the rest sub-period.
Optionally, when the test items of the first reaction cup and the second reaction cup are different, the test duration of the first reaction cup and the second reaction cup in the same rest subcycle is the same; or alternatively
When the test items of the first reaction cup and the second reaction cup are the same, the test time lengths of the first reaction cup and the second reaction cup in the same static subcycle are different.
The sample analyzer for controlling a test flow provided by the embodiment of the application divides a fixed test period into a plurality of moving subcycles and stationary subcycles, wherein test operations (such as sample adding, reagent adding, reading and the like) of the reaction cup at a plurality of operation positions can be realized in the stationary subcycles. Because a plurality of moving periods and a plurality of different operating positions are set, the reaction cup can be moved to the plurality of operating positions in one test period on the premise of fixing the main period, so that the reaction cup is matched with a plurality of test items with different durations, and different reaction container buffer areas are not required to be set for different moving parts. Therefore, the volume of the instrument can be reduced, and the cost of the instrument can be saved.
Additionally, the embodiment of the application also provides electronic equipment, which comprises: the test flow control device comprises a memory, a processor and a computer program stored in the memory and capable of running on the processor, wherein the computer program realizes the control method of the test flow when being executed by the processor.
The embodiment of the application also provides a computer readable storage medium, on which a computer program is stored, and when the computer program is executed by a processor, the control method of the test flow can achieve the same technical effects, and in order to avoid repetition, the description is omitted here. Wherein the computer readable storage medium is selected from Read-Only Memory (ROM), random access Memory (Random Access Memory, RAM), magnetic disk or optical disk.
Embodiments of the present application also provide a sample analyzer having the above readable storage medium. In one particular implementation, the sample analyzer may be a chemiluminescent analyzer.
It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
From the above description of the embodiments, it will be clear to those skilled in the art that the above-described embodiment method may be implemented by means of software plus a necessary general hardware platform, but of course may also be implemented by means of hardware, but in many cases the former is a preferred embodiment. Based on such understanding, the technical solution of the present application may be embodied essentially or in a part contributing to the prior art in the form of a software product stored in a storage medium (such as ROM/RAM, magnetic disk, optical disk), including several instructions for causing a terminal (which may be a mobile phone, a computer, a server, an air conditioner, or a network device, etc.) to perform the method described in the embodiments of the present application.
The embodiments of the present application have been described above with reference to the accompanying drawings, but the present application is not limited to the above-described embodiments, which are merely illustrative and not restrictive, and many forms may be made by those of ordinary skill in the art without departing from the spirit of the present application and the scope of the claims, which are also within the protection of the present application.
Those of ordinary skill in the art will appreciate that the elements and algorithm steps described in connection with the embodiments disclosed herein can be implemented as electronic hardware, or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the solution. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.
It will be clear to those skilled in the art that, for convenience and brevity of description, specific working procedures of the above-described systems, apparatuses and units may refer to corresponding procedures in the foregoing method embodiments, and are not repeated herein.
In the embodiments provided in the present application, it should be understood that the disclosed apparatus and method may be implemented in other manners. For example, the apparatus embodiments described above are merely illustrative, e.g., the division of the units is merely a logical function division, and there may be additional divisions when actually implemented, e.g., multiple units or components may be combined or integrated into another system, or some features may be omitted or not performed. Alternatively, the coupling or direct coupling or communication connection shown or discussed with each other may be an indirect coupling or communication connection via some interfaces, devices or units, which may be in electrical, mechanical or other form.
The units described as separate units may or may not be physically separate, and units shown as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.
In addition, each functional unit in each embodiment of the present application may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit.
The functions, if implemented in the form of software functional units and sold or used as a stand-alone product, may be stored in a computer-readable storage medium. Based on such understanding, the technical solution of the present application may be embodied essentially or in a part contributing to the prior art or in a part of the technical solution, in the form of a software product stored in a storage medium, including several instructions for causing a computer device (which may be a personal computer, a server, or a network device, etc.) to perform all or part of the steps of the methods described in the embodiments of the present application. And the aforementioned storage medium includes: a usb disk, a removable hard disk, a ROM, a RAM, a magnetic disk, or an optical disk, etc.
The foregoing is merely specific embodiments of the present application, but the scope of the present application is not limited thereto, and any person skilled in the art can easily think about changes or substitutions within the technical scope of the present application, and the changes and substitutions are intended to be covered by the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.
Claims (16)
1. A control method for controlling a sample testing process of a sample analyzer, wherein the testing process comprises a plurality of testing cycles, each testing cycle comprises M moving sub-cycles and N stationary sub-cycles, the moving sub-cycles and the stationary sub-cycles are arranged at intervals, at least one of the stationary sub-cycles corresponds to an operation position, and M and N are both positive integers, the method comprising:
receiving a first test procedure for a first reaction cup;
confirming a test action cycle of the plurality of test cycles of the first test flow;
after a first reaction cup enters a test action period, controlling the first reaction cup to move to or from a target operation position corresponding to a static subcycle adjacent to the moving subcycle in the moving subcycle;
And in the rest subcycle, performing a test operation on the first reaction cup at the target operation position.
2. The method of claim 1, further comprising, during the stationary subcycle, prior to performing a test operation on the first cuvette at the target operating position:
receiving a first test signal for a target device at the target operating location;
and in the rest subcycle, calling an operation device corresponding to the target operation position to execute test operation on the first reaction cup.
3. The method as recited in claim 1, further comprising:
receiving a second test procedure for testing a second cuvette that is sequentially positioned after the first cuvette;
confirming a test action cycle of the plurality of test cycles of the second test flow;
and after the test action cycle is executed on the first reaction cup, controlling the second reaction cup to enter the test action cycle.
4. A method according to claim 3, wherein the movement paths of the first cuvette and the second cuvette are identical during each test period.
5. A method according to claim 3, further comprising, after said controlling said second cuvette into said test action cycle:
receiving a second test signal for a target device at the target operating location;
and after the second reaction cup enters the static subcycle, calling an operation device corresponding to the target operation position to execute test operation on the second reaction cup.
6. A method according to claim 3, wherein when the test items of the first reaction cup and the second reaction cup are different, the test duration of the first reaction cup and the second reaction cup in the same stationary sub-period is the same; or alternatively
When the test items of the first reaction cup and the second reaction cup are the same, the test time lengths of the first reaction cup and the second reaction cup in the same static subcycle are different.
7. A sample analyzer for controlling a sample testing process, the testing process comprising a plurality of testing cycles, each testing cycle comprising M moving subcycles and N stationary subcycles, the moving subcycles and the stationary subcycles being spaced apart, wherein at least one of the stationary subcycles corresponds to an operational position, M and N each being a positive integer, the analyzer comprising: a host machine, a plurality of operating devices are arranged on the host machine; a carrying mechanism; a controller;
Wherein:
the controller is used for receiving a first test flow for the first reaction cup; confirming a test action cycle of the plurality of test cycles of the first test flow;
the bearing mechanism is used for driving the first reaction cup to move to or from a target operation position corresponding to a static subcycle adjacent to the moving subcycle in the moving subcycle after the first reaction cup enters the testing action cycle;
the operating means is for performing a test operation on the first cuvette at the target operating position during the stationary sub-period.
8. The analyzer of claim 7, wherein the analyzer comprises a plurality of sensors,
the controller is used for generating a first test signal of the target equipment at the target operation position according to the first test flow, and sending the first test signal to the target equipment;
the operating device is used for executing test operation on the first reaction cup in the stationary subcycle.
9. The analyzer of claim 7, wherein the analyzer comprises a plurality of sensors,
the bearing mechanism is used for driving a second reaction cup, which is positioned behind the first reaction cup in the test sequence, to enter the test action period after the test action period is executed on the first reaction cup.
10. The analyzer of claim 9, wherein the first cuvette and the second cuvette have the same path of movement during the test action cycle.
11. The analyzer of claim 9, wherein the analyzer comprises a plurality of sensors,
the controller is used for generating a second test signal of the target equipment at the target operation position according to the second test flow, and sending the second test signal to the target equipment;
the operating device is used for executing test operation on the second reaction cup after the second reaction cup enters the static subcycle.
12. The analyzer of claim 9, wherein when the test items of the first cuvette and the second cuvette are different, the test duration of the first cuvette and the second cuvette in the same stationary sub-period is the same; or alternatively
When the test items of the first reaction cup and the second reaction cup are the same, the test time lengths of the first reaction cup and the second reaction cup in the same static subcycle are different.
13. An electronic device, comprising:
memory, a processor and a computer program stored on the memory and executable on the processor, which when executed by the processor implements the control method of the test flow according to any one of claims 1 to 6.
14. A readable storage medium, characterized in that instructions in the storage medium, when executed by a processor of an electronic device, enable the electronic device to perform the control method of the test procedure of any one of claims 1 to 6.
15. A sample analyzer, characterized in that the sample analyzer has the readable storage medium of claim 14.
16. The sample analyzer of claim 15, wherein the sample analyzer is a chemiluminescent analyzer.
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