CN116251545A - Biological aerosol generating system - Google Patents

Biological aerosol generating system Download PDF

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Publication number
CN116251545A
CN116251545A CN202310300944.XA CN202310300944A CN116251545A CN 116251545 A CN116251545 A CN 116251545A CN 202310300944 A CN202310300944 A CN 202310300944A CN 116251545 A CN116251545 A CN 116251545A
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module
flow
aerosol
flow dividing
shunt
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CN116251545B (en
Inventor
胡秋实
周蕾
刘旭
田胜男
高娟
谢晴晴
陈婷婷
程方圆
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Zhangjiagang Yangtze River Delta Biosafety Research Center
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Zhangjiagang Yangtze River Delta Biosafety Research Center
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0095Preparation of aerosols
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/08Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J19/087Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing electric or magnetic energy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/20Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention belongs to the technical field of aerosol generators, and particularly relates to a biological aerosol generating system which comprises a generating module, a charge neutralization module and a second flow dividing module, wherein a first outlet end and a second outlet end are arranged on the generating module, the generating module is used for generating aerosol particles, outputting the aerosol particles through the first outlet end, simultaneously, sheath flow air can be input to the second flow dividing module through the second outlet end, and the first flow dividing module is used for carrying out first screening on the aerosol particles according to the particle size. According to the invention, the large-particle-size colloidal particles and the medium-particle-size colloidal particles can be separated by the shunt assembly under the dual actions of gravity and differential airflow, and the ultra-small colloidal particles are screened out by the electromigration device by utilizing the difference of the moving speeds of the colloidal particles with different particle sizes in an electric field, so that the device can generate small-particle-size colloidal particles with more accurate particle size range, and the aerosol particle size is controllable and the concentration is controllable.

Description

Biological aerosol generating system
Technical Field
The invention belongs to the technical field of aerosol generators, and particularly relates to a biological aerosol generating system.
Background
Aerosol refers to a colloidal system of small particles, solid or liquid, dispersed and suspended in a gaseous medium. In a dispersion system, the dispersed phase is typically small particles of liquid or solid, and the dispersion medium is gas. The density of these solid or liquid particles may vary slightly from the density of the gaseous medium or may vary considerably, typically with dispersed small particle sizes of 0.01 to 100 μm. In some public health events, aerosol becomes a transmission path of virus, and aerosol transmission path is correspondingly emphasized, so that more and more scientific research institutions and laboratories are researching aerosol more and more. The aerosol generator plays an important role as an important link.
There are two main types of bioaerosol generators in the current market:
a device is composed of small motor, piston cylinder and siphon sprayer. The working principle is as follows: after the small motor is electrified to work, a piston cylinder welded with a motor rotating shaft is driven to do circular and regular piston movement; a band of air flow of about 12kpa pressure is established in the piston cylinder; the air flow reaches the narrow opening of the atomizer through the hose connecting the piston cylinder and the two ends of the siphon atomizer, and the air is further compressed and sprayed out; the siphon cover is arranged outside the narrow opening and is used for driving the bacterial liquid in the grooves at the two sides in the siphon cover when high-pressure air is sprayed, so that the bacterial liquid is crushed by the high-pressure air to form aerosol.
Another type of bioaerosol generator is a glass spray bottle in which compressed air is used to blow a bacterial liquid directly to form an aerosol. For example, chinese patent CN104857901B discloses a microorganism aerosol generating device, which works on the following principles: externally connecting compressed air to the narrow-mouth tube to form an air column, and crushing bacterial liquid supplied by the peristaltic pump below to form aerosol.
When experimental study is carried out by utilizing small-particle-size aerosol, the required small-particle-size aerosol particle diameter range is mostly 0.5 to 10 mu m, however, when the small-particle-size aerosol is generated by the existing biological aerosol generating equipment, ultra-small particles with the particle size range of 0.01 to 0.5 mu m cannot be well screened out, so that the particle size of the aerosol particles cannot completely meet the experimental requirement, further experimental data are deviated, and the problem that the ultra-small-particle-size particles cannot be screened is solved by the aerosol generating system based on the problems.
Disclosure of Invention
The invention aims to provide a biological aerosol generating system, which can separate large-particle-size colloidal particles from medium-particle-size colloidal particles by using a shunt assembly under the dual actions of gravity and differential airflow, and screen out ultra-small colloidal particles by using the difference of moving speeds of the colloidal particles with different particle sizes in an electric field by using an electromigration device, so that the device can generate small-particle-size colloidal particles with more accurate particle size range, and the aerosol particle size is controllable and the concentration is controllable.
The technical scheme adopted by the invention is as follows:
a bioaerosol generating system, comprising a generating module and a main reaction module, wherein the main reaction module comprises a first shunt module, a charge neutralization module and a second shunt module;
the generating module is used for generating aerosol particles, outputting the aerosol particles through the first outlet end, and simultaneously inputting sheath flow gas to the second flow dividing module through the second outlet end;
the first flow distribution module is used for carrying out first screening on aerosol colloidal particles according to the size of the colloidal particles;
the charge neutralization module is used for adjusting the charge quantity of the aerosol colloidal particles positioned in the charge neutralization module;
the second flow dividing module is used for carrying out second screening on aerosol colloidal particles according to the size of the colloidal particles;
the first flow distribution module comprises a flow distribution assembly, an airflow hole is formed in the flow distribution assembly, a mist inlet and a third flow distribution port are further formed in the flow distribution assembly, and the mist inlet and a first outlet end of the generation module, the third flow distribution port and an input end of the charge neutralization module are communicated with each other;
the flow dividing assembly comprises a valve head, a valve body, a flow equalizing ring and a flow dividing block, wherein the flow dividing block is positioned at one end of the valve head, the valve body and the flow equalizing ring are sequentially assembled between the valve head and the flow dividing block, a third flow dividing opening is formed in the upper end of the outer side of the valve body, a first flow dividing opening and a second flow dividing opening are formed in the lower end of the outer side of the valve body, and the third flow dividing opening is formed in one end of the flow dividing block;
the mist inlet, the first diversion opening, the mist inlet and the second diversion opening are distributed at intervals in the extending direction of the airflow hole, and the aerosol inlet and the aerosol outlet are distributed at intervals in the flowing direction of sheath flow.
Further, the first flow dividing module further comprises an air generator and a filter accelerator, wherein the output end of the air generator is communicated with the input end of the filter accelerator, and the output end of the filter accelerator is communicated with the air flow hole of the flow dividing assembly through an air duct.
Further, the second flow splitting module comprises an electromigration device, a first electrode plate and a second electrode plate which are arranged at intervals are assembled in the electromigration device, a high-voltage electric field is formed between the first electrode plate and the second electrode plate, an aerosol inlet communicated with the charge neutralization module is formed in the first electrode plate, an aerosol outlet is formed in the second electrode plate, a sheath inflow opening and a sheath outflow opening are respectively formed in the upper end and the lower end of the electromigration device, the sheath inflow opening is communicated with the second outlet end of the generation module, and the electromigration device can conduct secondary screening on aerosol particles according to the size of the aerosol particles.
Further, the first shunt port is communicated with the generation module through a first return pipeline, and the second shunt port is communicated with an air duct at the output end of the filter accelerator through a second return pipeline.
Furthermore, a plurality of flow equalizing holes are distributed in the flow equalizing ring and the flow equalizing block in an annular mode, and the flow equalizing holes and the air flow holes in the flow equalizing ring are communicated.
Furthermore, an accelerating cavity is arranged in the flow dividing block, the section shape of the accelerating cavity is conical, and the accelerating cavity is communicated with a plurality of flow equalizing holes in the flow dividing block.
Furthermore, the filter accelerator has acceleration and filtering functions, the gas accelerated by the filter accelerator enters the inside of the flow dividing assembly through the gas guide pipe, the flow speed of the gas is recorded as V1, the aerosol colloidal particles generated by the generating module enter the inside of the flow dividing assembly through the mist inlet, the flow speed of the aerosol colloidal particles is recorded as V2, and the V1 is larger than V2.
Further, the flow speed of sheath flow gas which is conveyed to the interior of the electromigration device through the sheath flow inlet is denoted as V3, the flow speed of aerosol colloidal particles which are conveyed to the interior of the electromigration device through the aerosol inlet is denoted as V4, and the V3 is larger than V4.
Further, the second flow dividing module further comprises a collecting pipe, a pressure valve and an exhaust gas tank, wherein the collecting pipe is connected with the pressure valve through a parallel pipeline, one end of the parallel pipeline is communicated with an aerosol outlet, and the input end of the exhaust gas tank is communicated with a sheath outflow port.
Furthermore, both ends of the high-voltage electric field are provided with current equalizing networks, and two ends of the current equalizing networks, which are far away from each other, are provided with buffer cavities.
The invention has the technical effects that:
when the device is used, air and aerosol are simultaneously input into the shunt assembly, the large-particle-size colloidal particles and the medium-particle-size colloidal particles are separated under the dual effects of gravity and differential airflow, small-particle-size colloidal particles and ultra-small colloidal particles are obtained, after charge balance is carried out on the small-particle-size colloidal particles and the ultra-small colloidal particles by the charge neutralization module, the ultra-small colloidal particles are screened out by utilizing the difference of moving speeds of the colloidal particles with different particle sizes in an electric field by utilizing a high-voltage electric field in the electromigration device, so that the particle size of the aerosol particles generated by the device is more accurate, and meanwhile, the concentration of the aerosol generated by the device is regulated by a flow rate valve, so that the particle size and concentration of the aerosol generated by the device are controllable, and the experimental requirements can be better met;
when the distribution assembly is utilized to carry out first screening on aerosol, the large-particle-size colloidal particles are recycled through the first distribution opening, and the medium-particle-size colloidal particles formed by adhering a plurality of small-particle-size colloidal particles are dispersed through the accelerated air, so that the resource utilization rate and the occurrence efficiency of the small-particle-size colloidal particles are improved;
according to the invention, the inverted trapezoid diversion surfaces are respectively arranged on the first diversion opening and the second diversion opening, so that aerosol particles with different diameters can be more accurately diverted, and the diversion effect of the aerosol particles is improved.
Drawings
FIG. 1 is a system frame diagram of the overall invention;
FIG. 2 is an exploded view of a shunt assembly according to a first embodiment of the present invention;
FIG. 3 is a cross-sectional view of a flow splitting assembly in accordance with a first embodiment of the present invention;
FIG. 4 is a cross-sectional view of an electromigration device according to an embodiment of the invention;
FIG. 5 is a system frame diagram of a second embodiment of the present invention;
fig. 6 is a cross-sectional view of a switching module in a second embodiment of the present invention;
fig. 7 is a top view of a switching module in a second embodiment of the invention.
In the drawings, the list of components represented by the various numbers is as follows:
100. generating a module;
110. a compression tank; 111. a flow rate valve; 120. a sample liquid tank;
200. a first shunt module;
210. an air generator; 220. a filter accelerator; 230. a shunt assembly;
231. a valve head; 232. a valve body; 233. a flow equalizing ring; 234. a shunt block; 235. a sealing gasket; 236. a mist inlet; 237. a first shunt port; 238. a second shunt; 239. a third shunt port;
300. a charge neutralization module;
400. a second shunt module;
410. an electromigration device; 420. a collection pipe; 430. a pressure valve; 440. an exhaust gas tank;
411. a first electrode plate; 412. a second electrode plate; 413. a flow equalizing net; 414. a buffer chamber;
500. a switching module;
501. a housing; 502. an adjusting plate; 503. a servo motor; 504. connecting pipe;
600. and a comparison module.
Detailed Description
In order that the above-recited objects, features and advantages of the present invention will become more readily apparent, a more particular description of the invention will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, but the present invention may be practiced in other ways other than those described herein, and persons skilled in the art will readily appreciate that the present invention is not limited to the specific embodiments disclosed below.
Further, reference herein to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic can be included in at least one implementation of the invention. The appearances of the phrase "in one preferred embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments.
In describing the embodiments of the present invention in detail, the cross-sectional view of the device structure is not partially enlarged to a general scale, and the schematic drawings are only examples, which should not limit the scope of the present invention. In addition, the three-dimensional dimensions of length, width and depth should be included in actual fabrication.
Example 1
Referring to fig. 1, the present invention provides a bio-aerosol generating system, which comprises a generating module 100, and a main reaction module, wherein the main reaction module comprises a first diverting module 200, a charge neutralization module 300 and a second diverting module 400, the generating module 100 comprises a compression tank 110 and a sample liquid tank 120, the compression tank 110 and the sample liquid tank 120 are connected through a pipeline, a first outlet end is arranged on the sample liquid tank 120 and is connected with the first diverting module 200, a second outlet end is arranged on the compression tank 110 and is communicated with the second diverting module 400, the generating module 100 is used for generating aerosol particles and outputting the aerosol particles through the first outlet end, and meanwhile, sheath gas can be input into the second diverting module 400 through the second outlet end,
further, the sheath gas is injected into the compression tank 110, and the solution is injected into the sample tank 120, and in this embodiment, the sheath gas is preferably nitrogen, and the solution is a biological solution.
Preferably, a flow rate valve 111 is further provided between the compression tank 110 and the sample liquid tank 120, and the flow rate of the sheath gas flowing into the sample liquid tank 120 in a unit time can be adjusted by the flow rate valve 111, so that the concentration of the aerosol particles can be adjusted.
It should be noted that, in the present embodiment, the colloidal particle size range is defined as an ultra-small colloidal particle with a particle size of 0.01 to 0.5 μm, the colloidal particle size range is defined as a small colloidal particle with a particle size of 0.5 to 10 μm, the colloidal particle size range is defined as a medium-sized colloidal particle with a particle size of 10 to 40 μm, and the colloidal particle size range is defined as a large colloidal particle with a particle size of 40 to 100 μm, which are only for better describing the working process of the present application, and do not represent specific limitations of the present application.
In this embodiment, after the device is started, the sheath flow gas inside the compression tank 110 flows into the sample liquid tank 120, so that the solution inside the sample liquid tank 120 is atomized, and aerosol colloidal particles are generated, and the aerosol colloidal particles flow into the first diversion module 200 through the first outlet end on the sample liquid tank 120, and at this time, the diameters of the aerosol colloidal particles are different.
Referring to fig. 1, the method further includes: the first flow dividing module 200, the first flow dividing module 200 includes an air generator 210, a filter accelerator 220 and a flow dividing assembly 230, the inside of the flow dividing assembly 230 is provided with an air flow hole, the output end of the air generator 210 is communicated with the input end of the filter accelerator 220, the output end of the filter accelerator 220 is communicated with the air flow hole of the flow dividing assembly 230 through an air duct, wherein the air generator 210 can generate clean air, the filter accelerator 220 has accelerating and filtering functions, and the air can filter and accelerate the crystallized air and convey the crystallized air into the air flow hole inside the flow dividing assembly 230;
the diverter assembly 230 comprises a valve head 231, a valve body 232, a flow equalizing ring 233, a diverter block 234 and a sealing gasket 235, wherein the diverter block 234 is positioned at one end of the valve head 231, the valve body 232 and the flow equalizing ring 233 are sequentially assembled between the valve head 231 and the diverter block 234 from one end close to the valve head 231 to one end far away from the valve head 231, the sealing gasket 235 is assembled between the valve head 231 and the valve body 232, a mist inlet 236 is arranged at the upper end of the outer side of the valve body 232, a first diverter 237 and a second diverter 238 are arranged at the lower end of the outer side of the valve body 232, the first diverter 237 and the sample liquid tank 120 are communicated through a first backflow pipeline, the second diverter 238 and an air duct at the output end of the filter accelerator 220 are communicated through a second backflow pipeline, a one-way valve is arranged in the second backflow pipeline, one end of the diverter block 234 far away from the valve head 231 is provided with a third diverter 239, and the first outlet end 236 on the sample liquid tank 120 and the third diverter outlet 239 and the input end of the charge neutralization module 300 are communicated with each other, and in particular, in this embodiment, after the air filtered and accelerated by the filter accelerator 220 flows into the air flow hole, the air flow direction is parallel to the horizontal direction;
further, the upper ends of the first diversion opening 237 and the second diversion opening 238 are provided with diversion surfaces, the cross section of each diversion surface is inverted trapezoid, and the arrangement of the diversion surfaces can conduct more accurate diversion on aerosol particles with different diameters, so that the diversion effect of aerosol particles is improved.
Here, the mist inlet 236 and the first shunt opening 237 and the mist inlet 236 and the second shunt opening 238 are all spaced apart in the extending direction of the airflow hole;
further, a plurality of flow equalizing holes are annularly distributed in the flow equalizing ring 233 and the flow equalizing block 234, the flow equalizing holes in the flow equalizing ring 233 correspond to the flow equalizing holes in the flow equalizing block 234 one by one, wherein the flow equalizing holes in the flow equalizing ring 233 are communicated with the flow equalizing holes, an accelerating cavity is arranged in the flow equalizing block 234, the section of the accelerating cavity is conical, the accelerating cavity is communicated with the flow equalizing holes in the flow equalizing block 234, and the accelerating cavity is arranged, so that small-particle-size colloidal particles are accelerated when passing through the accelerating cavity along with gas, and adhered aerosol is dispersed when passing through a third narrower shunt opening 239, so that the small-particle-size colloidal particles are distributed more uniformly and stably;
it should be noted that, the gas accelerated by the filter accelerator 220 enters the inside of the flow dividing assembly 230 through the gas guide tube, the flow speed thereof is denoted as V1, the aerosol colloidal particles generated by the generating module 100 enter the inside of the flow dividing assembly 230 through the mist inlet 236, the flow speed thereof is denoted as V2, and V1 is greater than V2;
it should be noted that, the one end of the first return line far away from the first shunt port 237 penetrates through the sample liquid tank 120 and is submerged in the solution, through the above scheme, sheath gas can be prevented from entering the first return line, and in a specific embodiment, a direction control element such as: the one-way valve prevents sheath flow gas from entering the first return pipeline;
in this embodiment, when the device is in use, aerosol is generated by the generating module 100, the aerosol enters the inside of the diversion component 230 through the mist inlet 236, meanwhile, the air generator 210 and the filter accelerator 220 are operated, clean air is generated after the operation of the air generator 210, the clean air is filtered and accelerated and conveyed into the inside of the diversion component 230 through the filter accelerator 220, and air flow is formed in the inside of the diversion component 230, and when the aerosol colloidal particle moves along the air flow direction due to V1 being larger than V2, the aerosol colloidal particle moves downwards under the action of gravity and sheath air, wherein the colloidal particle with large particle size enters the inside of the first diversion port 237, the colloidal particle with medium particle size enters the inside of the second diversion port 238, the colloidal particle with small particle size and the colloidal particle with ultra-small particle size enter the inside of the third diversion port 239, the colloidal particle with large particle size enters the inside of the first diversion port 237 and then flows back into the sample liquid tank 120 along the first backflow pipeline, the middle particle size colloidal particles are washed away by the accelerated clean air to be dispersed into small particle size colloidal particles, enter the inside of the shunt assembly 230 again and enter the inside of the third shunt opening 239, and through the cooperation of the air generator 210, the filter accelerator 220 and the shunt assembly 230, the device not only can directly recycle and reuse the colloidal particles with large particle size, but also can disperse the middle particle size colloidal particles formed by adhesion of a plurality of small particle size colloidal particles, at the moment, the non-dispersed middle particle size colloidal particles can be gradually adhered to form large particle size colloidal particles in the circulating flow process and flow back to the sample liquid tank 120 through the first shunt opening 237, and then make first reposition of redundant personnel module 200 utilize the micelle of different particle diameters to realize first screening under gravity and differential air current's dual effect, can stably acquire small diameter micelle and super small micelle.
The charge neutralization module 300 is used for adjusting the charge amount of the aerosol particles located inside the charge neutralization module 300, so that the aerosol particles are in a charge balance state before entering the second shunt module 400, and the input end of the charge neutralization module 300 is connected with the third shunt port 239 through a pipeline;
in this embodiment, the small particle size colloidal particles and ultra-small colloidal particles after first screening by the first splitting module 200 enter the charge neutralization module 300 through the third splitting port 239, and the charge neutralization module 300 can charge balance the aerosol colloidal particles with positive charges or negative charges, so that the aerosol colloidal particles are not charged.
The second flow dividing module 400 includes an electromigration 410, a collecting pipe 420, a pressure valve 430 and an exhaust gas tank 440, a first electrode plate 411 and a second electrode plate 412 are assembled in the electromigration 410 at intervals, a high-voltage electric field is formed between the first electrode plate 411 and the second electrode plate 412, an aerosol inlet communicated with the charge neutralization module 300 is arranged on the first electrode plate 411, an aerosol outlet is arranged on the second electrode plate 412, a sheath inflow port and a sheath outflow port are respectively arranged at the upper end and the lower end of the electromigration 410, the sheath inflow port is communicated with a second outlet end on the compression tank 110, both ends of the high-voltage electric field are respectively provided with a flow equalizing net 413, two flow equalizing nets 413 are respectively arranged at the ends far away from each other, buffer cavities 414 are respectively arranged at the two ends of the flow equalizing net 413, the electromigration 410 can screen the aerosol collecting pipe for the second time according to the size of colloidal particles, the pressure valve 430 and the first electrode plate 411 are connected through parallel pipelines, one end of the parallel pipelines is communicated with the aerosol outlet, and the input end of the exhaust gas tank 440 is communicated with the sheath outflow port;
here, the aerosol inlets and the aerosol outlets are spaced apart in the flow direction of the sheath flow gas;
further, the flow rate of the sheath gas supplied from the compression tank 110 to the interior of the electromigration device 410 through the sheath inflow port is denoted as V3, the flow rate of the aerosol particles supplied from the aerosol inlet to the interior of the electromigration device 410 is denoted as V4, and V3 is greater than V4;
it should be noted that, in the present embodiment, taking the first electrode plate 411 connected to the negative voltage module and the second electrode plate 412 connected to the ground line as an example, the above voltage connection mode is only for better describing the working process of the present application, and is not meant to limit the present application specifically
In this embodiment, after the device is started, the compression tank 110 conveys sheath flow gas to the interior of the electromigration device 410 through the second outlet end to form sheath flow, meanwhile, after the aerosol particles passing through the interior of the charge neutralization module 300 enter the interior of the electromigration device 410 through the aerosol inlet, the aerosol particles are negatively charged under the action of the first electrode plate 411, the particles with negative charges move under the dual actions of the sheath flow and the charge adsorption of the second electrode plate 412, wherein small particle size particles enter the aerosol outlet, ultra-small particle size particles enter the interior of the exhaust gas tank 440 along with the sheath flow gas, the ultra-small particle size particles are screened out by the electromigration device 410 by utilizing the difference of the moving speeds of the particles with different particle sizes in an electric field, so that the diameter of the aerosol particles generated by the device is more stable and controllable, meanwhile, the flow rate of the aerosol particles flowing into the sample liquid tank 120 in unit time is regulated through the flow rate valve 111, the concentration of the aerosol particles with negative charges is regulated, and the particle size of the aerosol particles generated by the device is controllable, and the concentration of the aerosol particles is controllable.
The working principle of the invention is as follows:
the starting device inputs sheath flow gas to the inside of the sample liquid tank 120 and the electromigration device 410 through the compression tank 110, at this moment, the flow rate of the sheath flow gas flowing into the inside of the sample liquid tank 120 in unit time is regulated through the flow rate valve 111, the concentration of the aerosol particles is regulated, the sheath flow gas is produced after entering the inside of the sample liquid tank 120, aerosol mist enters the inside of the shunt assembly 230 through the mist inlet 236, simultaneously, the air generator 210 generates air, and the air is filtered and accelerated through the filter accelerator 220, and then is conveyed into the inside of the shunt assembly 230, the aerosol particles in the inside of the shunt assembly 230 have the moving speed difference under the dual actions of gravity and differential airflow, wherein the large particle size particles flow back to the inside of the sample liquid tank 120 through the first shunt port 237 and are recycled, the medium particle size particles flow back to the air guide pipe, the medium particle size particles formed by small particle size adhesion are washed open through the medium particle size particles in the air guide pipe, the small particle size particles and the super particle particles enter the inside of the shunt assembly 230 through the third shunt port 239 and the inside the electric field, the small particle size particles and the super particle size particles can flow into the inside the electric field of the small particle size particles, and the super particle size particles can flow into the electric field of the small particle size particles through the electric field device 300, and the super particle size particles can flow into the small particle size particles through the electric field device, and the electric field can move the small particle size particles and the super particle size particles can flow into the electric field device 410, and the small particle size particles can move the small particle particles and the particle size particles can flow into the electric field.
Example two
This embodiment is based on the first embodiment, and further optimizes the model
In this embodiment, a switching module 500 is disposed between the generating module 100 and the first splitting module 200 and between the generating module 100 and the second splitting module 400, and the generating module 100 is further connected with a plurality of comparing modules 600 through the switching module 500, and the switching module 500 is used for switching the generating module 100 between the main reaction module and the plurality of comparing modules 600;
the overall composition of the comparison module 600 is the same as that of the main reaction module, and the difference is that specific parameters thereof are different, such as, but not limited to, difference of the number of shunt ports in the charge neutralization module 300; the purpose is that in the normal generating process, the generating module 100 can be connected into different comparing modules 600 by using the switching module 500 according to the actual requirement, so as to realize comparison by different comparing modules 600, thereby selecting different reaction processes according to the actual use requirement, and most importantly, the switching module 500 can be used for realizing the switching of part of the modules, if the initial state is the connection of the main reaction module, the switching module can be used for respectively selecting and switching the first splitting module 200 and the second splitting module 400, so that more choices can be realized by using the cross combination mode, and more choices are provided for the actual use.
Specifically, the switching module 500 includes a housing 501, a regulating disc 502 is disposed in the housing 501, a servo motor 503 is disposed in the inner bottom of the housing 501, an output shaft of the servo motor 503 is connected to the center of the regulating disc 502, an L-shaped through hole is formed in the housing 502, an upper end of the L-shaped through hole is connected to a corresponding module through a hose, and a connection part is at least adapted to a rotary joint, so as to realize normal rotation, in addition, at least four connection pipes 504 are connected to the housing 501, and the four connection pipes 504 respectively correspond to different modules (more combinations are specifically referred to, and specific details are not described herein) when the servo motor 503 rotates once, the L-shaped through hole is connected into the corresponding connection pipe 504.
In this embodiment, when a reaction is required to be performed by using different modules, the servo motor 503 is used to drive the adjusting disc to rotate, so that the L-shaped through hole is connected into the corresponding connecting pipe 504, the switching mode is simple, and the equipment is more arranged and combined, so that the selection can be performed according to actual requirements.
The foregoing is merely a preferred embodiment of the present invention and it should be noted that modifications and adaptations to those skilled in the art may be made without departing from the principles of the present invention, which are intended to be comprehended within the scope of the present invention. Structures, devices and methods of operation not specifically described and illustrated herein, unless otherwise indicated and limited, are implemented according to conventional means in the art.

Claims (10)

1. A bioaerosol generating system comprising a generating module (100), and a main reaction module comprising a first shunt module (200), a charge neutralization module (300) and a second shunt module (400), characterized in that:
the generating module (100) is provided with a first outlet end and a second outlet end, the generating module (100) is used for generating aerosol particles, outputting the aerosol particles through the first outlet end, and simultaneously inputting sheath gas to the second flow dividing module (400) through the second outlet end;
the first flow distribution module (200) is used for carrying out first screening on aerosol colloidal particles according to the size of the colloidal particles;
the charge neutralization module (300) is used for adjusting the charge quantity of the aerosol colloidal particles positioned in the charge neutralization module;
the second flow dividing module (400) is used for carrying out second screening on aerosol colloidal particles according to the size of the colloidal particles;
the first shunt module (200) comprises a shunt assembly (230), an airflow hole is formed in the shunt assembly (230), a mist inlet (236) and a third shunt opening (239) are further formed in the shunt assembly (230), and the mist inlet (236) is communicated with a first outlet end of the generation module (100) and an input end of the third shunt opening (239) and the charge neutralization module (300);
the flow dividing assembly (230) comprises a valve head (231), a valve body (232), a flow equalizing ring (233) and a flow dividing block (234), the flow dividing block (234) is positioned at one end of the valve head (231), the valve body (232) and the flow equalizing ring (233) are sequentially assembled between the valve head (231) and the flow dividing block (234), a third flow dividing opening (239) is formed in the upper end of the outer side of the valve body (232), a first flow dividing opening (237) and a second flow dividing opening (238) are formed in the lower end of the outer side of the valve body (232), and the third flow dividing opening (239) is formed in one end of the flow dividing block (234);
the mist inlet (236) and the first shunt opening (237) and the mist inlet (236) and the second shunt opening (238) are distributed at intervals in the extending direction of the airflow hole, and the aerosol inlet and the aerosol outlet are distributed at intervals in the flowing direction of sheath flow air.
2. A bioaerosol generating system as defined in claim 1, wherein: the first flow dividing module (200) further comprises an air generator (210) and a filter accelerator (220), wherein the output end of the air generator (210) is communicated with the input end of the filter accelerator (220), and the output end of the filter accelerator (220) is communicated with an airflow hole of the flow dividing assembly (230) through an air duct.
3. A bioaerosol generating system as defined in claim 1, wherein: the second flow dividing module (400) comprises an electromigration device (410), a first electrode plate (411) and a second electrode plate (412) which are arranged at intervals are assembled in the electromigration device (410), a high-voltage electric field is formed between the first electrode plate (411) and the second electrode plate (412), an aerosol inlet communicated with the charge neutralization module (300) is formed in the first electrode plate (411), an aerosol outlet is formed in the second electrode plate (412), a sheath inflow opening and a sheath outflow opening are formed in the upper end and the lower end of the electromigration device (410) respectively, the sheath inflow opening is communicated with the second outlet end of the generation module (100), and the electromigration device (410) can conduct second screening on aerosol particles according to particle sizes.
4. A bioaerosol generating system as defined in claim 1, wherein: the first shunt opening (237) is communicated with the generation module (100) through a first return pipeline, and the second shunt opening (238) is communicated with an air duct at the output end of the filtering accelerator (220) through a second return pipeline.
5. A bioaerosol generating system as defined in claim 1, wherein: a plurality of flow equalizing holes are distributed in the flow equalizing ring (233) and the flow dividing block (234) in an annular mode, and the flow equalizing holes and the air flow holes in the flow equalizing ring (233) are communicated.
6. A bioaerosol generating system as defined in claim 1, wherein: the inside of reposition of redundant personnel piece (234) is provided with the chamber that accelerates, the cross-sectional shape of chamber is conical with a plurality of flow equalizing holes that are located inside reposition of redundant personnel piece (234) are linked together to the chamber that accelerates.
7. A bioaerosol generating system as defined in claim 1, wherein: the filter accelerator (220) has acceleration and filtering functions, gas accelerated by the filter accelerator (220) enters the inside of the flow dividing assembly (230) through the gas guide pipe, the flow speed of the gas is recorded as V1, aerosol colloidal particles generated by the generating module (100) enter the inside of the flow dividing assembly (230) through the mist inlet (236), the flow speed of the gas is recorded as V2, and the V1 is larger than V2.
8. A bioaerosol generating system as defined in claim 1, wherein: the generating module (100) is used for conveying sheath flow gas into the electromigration device (410) through a sheath flow inlet, the flowing speed of the sheath flow gas is denoted as V3, the flowing speed of the sheath flow gas is denoted as V4, and the flowing speed of the aerosol particle conveyed into the electromigration device (410) through the aerosol inlet is larger than V4.
9. A bioaerosol generating system as defined in claim 1, wherein: the second flow dividing module (400) further comprises a collecting pipe (420), a pressure valve (430) and an exhaust gas tank (440), wherein the collecting pipe (420) and the pressure valve (430) are connected through parallel pipelines, one end of each parallel pipeline is communicated with an aerosol outlet, and the input end of the exhaust gas tank (440) is communicated with a sheath outflow opening.
10. A bioaerosol generating system as defined in claim 1, wherein: both ends of the high-voltage electric field are provided with current equalizing networks (413), and one ends, far away from each other, of the two current equalizing networks (413) are provided with buffer cavities (414).
CN202310300944.XA 2023-03-27 2023-03-27 Biological aerosol generating system Active CN116251545B (en)

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US20060266132A1 (en) * 2005-05-31 2006-11-30 Ut-Battelle, Llc Stackable differential mobility analyzer for aerosol measurement
CN114307876A (en) * 2021-12-06 2022-04-12 青岛众瑞智能仪器股份有限公司 Monodisperse aerosol generating system
CN216747273U (en) * 2021-12-06 2022-06-14 青岛众瑞智能仪器股份有限公司 Monodisperse aerosol generating system
WO2023029740A1 (en) * 2021-08-31 2023-03-09 北京航空航天大学 Wide-temperature nanoparticle counter

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060266132A1 (en) * 2005-05-31 2006-11-30 Ut-Battelle, Llc Stackable differential mobility analyzer for aerosol measurement
WO2023029740A1 (en) * 2021-08-31 2023-03-09 北京航空航天大学 Wide-temperature nanoparticle counter
CN114307876A (en) * 2021-12-06 2022-04-12 青岛众瑞智能仪器股份有限公司 Monodisperse aerosol generating system
CN216747273U (en) * 2021-12-06 2022-06-14 青岛众瑞智能仪器股份有限公司 Monodisperse aerosol generating system

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