CN116211923A - Traditional Chinese medicine medicated bath preparation for treating tinea, and preparation method and application thereof - Google Patents
Traditional Chinese medicine medicated bath preparation for treating tinea, and preparation method and application thereof Download PDFInfo
- Publication number
- CN116211923A CN116211923A CN202310417016.1A CN202310417016A CN116211923A CN 116211923 A CN116211923 A CN 116211923A CN 202310417016 A CN202310417016 A CN 202310417016A CN 116211923 A CN116211923 A CN 116211923A
- Authority
- CN
- China
- Prior art keywords
- parts
- traditional chinese
- chinese medicine
- soaking
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 125
- 239000003788 bath preparation Substances 0.000 title claims abstract description 67
- 208000002474 Tinea Diseases 0.000 title claims abstract description 37
- 241000130764 Tinea Species 0.000 title claims abstract description 35
- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 24
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 23
- 241001071917 Lithospermum Species 0.000 claims abstract description 23
- 235000001855 Portulaca oleracea Nutrition 0.000 claims abstract description 23
- 241000746375 Andrographis Species 0.000 claims abstract description 19
- 241000037740 Coptis chinensis Species 0.000 claims abstract description 18
- 241000202726 Bupleurum Species 0.000 claims abstract description 17
- 241000222336 Ganoderma Species 0.000 claims abstract description 16
- 201000004681 Psoriasis Diseases 0.000 claims abstract description 15
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 claims abstract description 14
- 235000003097 Artemisia absinthium Nutrition 0.000 claims abstract description 14
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 claims abstract description 14
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims abstract description 14
- 239000001138 artemisia absinthium Substances 0.000 claims abstract description 14
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims abstract description 14
- 208000010195 Onychomycosis Diseases 0.000 claims abstract description 12
- 201000005882 tinea unguium Diseases 0.000 claims abstract description 12
- 238000002791 soaking Methods 0.000 claims description 43
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 42
- 239000000052 vinegar Substances 0.000 claims description 35
- 235000021419 vinegar Nutrition 0.000 claims description 35
- 239000000843 powder Substances 0.000 claims description 25
- 241000245665 Taraxacum Species 0.000 claims description 23
- 241000219304 Portulacaceae Species 0.000 claims description 22
- 239000002994 raw material Substances 0.000 claims description 15
- 240000004534 Scutellaria baicalensis Species 0.000 claims description 9
- 235000017089 Scutellaria baicalensis Nutrition 0.000 claims description 9
- 240000008397 Ganoderma lucidum Species 0.000 claims description 7
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims description 7
- 238000002156 mixing Methods 0.000 claims description 7
- 238000007873 sieving Methods 0.000 claims description 7
- 241000092668 Artemisia capillaris Species 0.000 claims description 6
- 235000008658 Artemisia capillaris Nutrition 0.000 claims description 6
- 241000207929 Scutellaria Species 0.000 claims description 6
- 238000000227 grinding Methods 0.000 claims description 6
- 239000006228 supernatant Substances 0.000 claims description 6
- 241000218202 Coptis Species 0.000 claims description 5
- 235000002991 Coptis groenlandica Nutrition 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 240000006891 Artemisia vulgaris Species 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 22
- 240000001851 Artemisia dracunculus Species 0.000 abstract description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 9
- 208000024891 symptom Diseases 0.000 abstract description 4
- 229940088597 hormone Drugs 0.000 abstract description 3
- 239000005556 hormone Substances 0.000 abstract description 3
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 3
- 244000052616 bacterial pathogen Species 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 241000050051 Chelone glabra Species 0.000 abstract 1
- 244000234609 Portulaca oleracea Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 20
- 239000000047 product Substances 0.000 description 12
- 210000004185 liver Anatomy 0.000 description 10
- 235000019640 taste Nutrition 0.000 description 8
- 208000003251 Pruritus Diseases 0.000 description 7
- 201000010099 disease Diseases 0.000 description 6
- 244000118350 Andrographis paniculata Species 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 210000002216 heart Anatomy 0.000 description 5
- 230000007803 itching Effects 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 239000011550 stock solution Substances 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 241000233866 Fungi Species 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 230000000740 bleeding effect Effects 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 230000036039 immunity Effects 0.000 description 4
- 210000002429 large intestine Anatomy 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 206010037844 rash Diseases 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- 241001480043 Arthrodermataceae Species 0.000 description 3
- 240000000774 Cunila origanoides Species 0.000 description 3
- 235000018274 Cunila origanoides Nutrition 0.000 description 3
- 235000014866 Dictamnus albus Nutrition 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 230000037304 dermatophytes Effects 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 238000010926 purge Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 239000003053 toxin Substances 0.000 description 3
- 231100000765 toxin Toxicity 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 206010005913 Body tinea Diseases 0.000 description 2
- 206010015150 Erythema Diseases 0.000 description 2
- 208000010201 Exanthema Diseases 0.000 description 2
- 208000022535 Infectious Skin disease Diseases 0.000 description 2
- 201000010618 Tinea cruris Diseases 0.000 description 2
- 206010067197 Tinea manuum Diseases 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 206010000269 abscess Diseases 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 231100000321 erythema Toxicity 0.000 description 2
- 201000005884 exanthem Diseases 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000001976 improved effect Effects 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 206010040882 skin lesion Diseases 0.000 description 2
- 231100000444 skin lesion Toxicity 0.000 description 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 201000003875 tinea corporis Diseases 0.000 description 2
- 201000004647 tinea pedis Diseases 0.000 description 2
- 210000003932 urinary bladder Anatomy 0.000 description 2
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- 206010012435 Dermatitis and eczema Diseases 0.000 description 1
- 208000007163 Dermatomycoses Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010016936 Folliculitis Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 206010018691 Granuloma Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 206010050167 Lymph node abscess Diseases 0.000 description 1
- 241000245301 Nymphoides Species 0.000 description 1
- 235000000476 Nymphoides peltata Nutrition 0.000 description 1
- 206010048886 Onychoclasis Diseases 0.000 description 1
- 206010033474 Pain of skin Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 240000006079 Schisandra chinensis Species 0.000 description 1
- 235000008422 Schisandra chinensis Nutrition 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 206010043866 Tinea capitis Diseases 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 239000006172 buffering agent Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 201000003929 dermatomycosis Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 208000035474 group of disease Diseases 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 125000003367 polycyclic group Chemical group 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 235000019643 salty taste Nutrition 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- 235000019614 sour taste Nutrition 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 229940126673 western medicines Drugs 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
The invention provides a traditional Chinese medicine bath preparation for treating tinea, a preparation method and application thereof, belonging to the technical field of traditional Chinese medicines, and comprising 1-15 parts of lucid ganoderma, 1-15 parts of honeysuckle, 1-15 parts of lithospermum, 1-15 parts of dandelion, 1-15 parts of coptis chinensis, 1-15 parts of virgate wormwood herb, 1-10 parts of bupleurum, 1-10 parts of common andrographis herb, 1-10 parts of cortex dictamni, 1-10 parts of baical skullcap root and 1-10 parts of purslane. The traditional Chinese medicine bath preparation used in the invention has no toxic or side effect, eliminates the side effect after hormone medicine treatment, kills germs, treats both symptoms and root causes, and fundamentally treats psoriasis, onychomycosis and other skin tinea diseases.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine medicated bath preparation for treating tinea, and a preparation method and application thereof.
Background
Tinea belongs to infectious skin diseases, and the skin has red rash or small red plaque, and the more the skin is scratched, the more the affected area is widened. The skin lesions may become dark red over time, with thin scales thereon, and may have pigmentation in the local area. Patients often have itching and the local skin is mossy due to scratching. Dermatomycosis is a superficial infection of hair, skin and nails caused by dermatophytes, but it is also reported to cause a deep infection. Clinically, it is usually tinea capitis, tinea corporis, tinea cruris, tinea manuum, tinea pedis and tinea rubella. The skin tinea bacteria invade the horny layer to cause tinea corporis, tinea cruris, tinea manus and pedis and the like, and the skin tinea bacteria appear as hyphae separated by branches in dandruff, can be broken into chain spores, the skin lesions are generally round or polycyclic, are scattered singly or fused with each other, and can cause tissue reaction from erythema, scales to crusting, suppuration and even granuloma, and subjective feeling is avoided or itching is caused to different degrees. Dermatophytes involve the nail plate and are usually characterized by thickening, discoloration and breakage of the nail plate, and the perinail tissue is generally free of inflammation and pain. Dermatophytes cause deep tissue infection in rare cases, and are manifested by cellulitis, folliculitis, tinea, subcutaneous tissue abscess, lymph node abscess, podophy abscess, wart hyperplasia, and the like.
Tinea is a common and frequently occurring group of diseases, next to dermatitis and eczema, and is the leading one among the infectious skin diseases. Psoriasis (Psoriasis) is a common chronic skin tinea and is commonly known as Psoriasis. Called "cowhide," there are two understandings: firstly, the disease repeatedly attacks and is difficult to radically cure, and the toughness of the disease is like cowhide; secondly, some patients have rough skin surface like cowhide due to the repeated attack and treatment process of the rash. Psoriasis is complicated in pathogenesis, and the treatment by the antifungal western medicines often has no ideal effect, is stubborn in pathology and repeated in illness state, and causes a certain wound to patients in psychology and physiology during the pathogenesis. The onychomycosis is also a common and frequent skin disease, the onychomycosis is difficult to treat, the common modes for treating the onychomycosis include an external antibacterial medicament, an oral antibacterial medicament and a surgical nail removing therapy, but the antibacterial medicament is usually an antibiotic, the external and oral antibacterial medicament has larger side effect, and the surgical nail removing therapy brings larger pain to patients. Because itch and pain of skin diseases can lead patients to sit restlessness, and the infectivity of the diseases also causes a certain threat to skin health of other people, and seriously affects life and work of people, a traditional Chinese medicine medicated bath preparation for treating skin tinea and a preparation method thereof are needed to be researched.
Disclosure of Invention
Therefore, the invention aims to provide a traditional Chinese medicine medicated bath preparation for treating skin tinea, a preparation method and application thereof, and the traditional Chinese medicine medicated bath preparation has the effects of relieving itching and removing tinea, purging fire and removing toxin, and can effectively treat skin tinea such as psoriasis, onychomycosis and the like.
In order to achieve the above object, the present invention provides the following technical solutions:
the invention provides a traditional Chinese medicine medicated bath preparation for treating tinea, which comprises the following raw materials in parts by weight: 1 to 15 parts of lucid ganoderma, 1 to 15 parts of honeysuckle, 1 to 15 parts of lithospermum, 1 to 15 parts of dandelion, 1 to 15 parts of coptis chinensis, 1 to 15 parts of virgate wormwood herb, 1 to 10 parts of bupleurum, 1 to 10 parts of common andrographis herb, 1 to 10 parts of cortex dictamni, 1 to 10 parts of baikal skullcap root and 1 to 10 parts of purslane.
Preferably, the traditional Chinese medicine medicated bath preparation comprises the following raw materials in parts by weight: 3 to 12 parts of lucid ganoderma, 4 to 11 parts of honeysuckle, 2 to 13 parts of lithospermum, 3 to 14 parts of dandelion, 4 to 11 parts of coptis chinensis, 4 to 12 parts of virgate wormwood herb, 3 to 7 parts of bupleurum, 2 to 8 parts of common andrographis herb, 3 to 9 parts of cortex dictamni, 2 to 9 parts of baical skullcap root and 1.5 to 8 parts of purslane.
Preferably, the traditional Chinese medicine medicated bath preparation also comprises white vinegar with the vinegar acidity of 1-10%.
The invention also provides a preparation method of the traditional Chinese medicine medicated bath preparation, which comprises the following steps:
mixing the ganoderma lucidum, the honeysuckle, the lithospermum, the dandelion, the coptis, the capillary artemisia, the bupleurum, the andrographis herb, the cortex dictamni, the scutellaria baicalensis and the purslane, grinding into powder, sieving to obtain traditional Chinese medicine powder, adding white vinegar for soaking, and taking supernatant to obtain the traditional Chinese medicine bath preparation.
Preferably, the soaking comprises a first soaking and a second soaking, wherein the temperature of the first soaking is 20-25 ℃, and the soaking time is 20-28 hours; the temperature of the second soaking is 20-25 ℃, and the soaking time is more than 7 days; the acetic acid degree of the white vinegar soaked for the second time is twice that of the white vinegar soaked for the first time.
Preferably, in the above preparation method, the acidity of the white vinegar is 1% -10%.
Preferably, the mesh number of the sieve is 80-100 mesh.
Preferably, the mass ratio of the traditional Chinese medicine powder to the white vinegar used for the first soaking is 1:1-3; the mass ratio of the traditional Chinese medicine powder to the white vinegar used for the second soaking is 1:1-3.
The invention also provides an application of the traditional Chinese medicine medicated bath preparation or the traditional Chinese medicine medicated bath preparation prepared by the preparation method in preparing the medicine for treating the tinea.
Preferably, the tinea comprises one or two of psoriasis and onychomycosis.
Compared with the prior art, the invention has the following beneficial effects:
the invention provides a traditional Chinese medicine medicated bath preparation for treating skin tinea and a preparation method and application thereof, wherein the principal drug in the traditional Chinese medicine medicated bath preparation is lucid ganoderma, the ministerial drug is honeysuckle, the adjuvant drug is lithospermum, the drug is dandelion, coptis chinensis, herba artemisiae, radix bupleuri, common andrographis herb, cortex dictamni, radix scutellariae and purslane, the lucid ganoderma used in the formula has the effects of regulating immunity, protecting liver, detoxifying, improving blood circulation and promoting metabolism, and the traditional Chinese medicine medicated bath preparation is used together with medicines of honeysuckle, lithospermum, dandelion, coptis chinensis and schisandra chinensis, detoxifying, eruption and furuncle eliminating, heat clearing and exterior relieving, can effectively improve human immunity, improve microcirculation, kill epidermomyces, and is assisted with traditional Chinese medicines of purslane, cortex dictamni, radix scutellariae, radix bupleuri, herba andrographis provided with the functions of cooling blood, stopping bleeding, dehumidifying, relieving itching, drying dampness and detumescence, relieving the symptoms of patients such as pruritus, floating heart qi and the like, and the effects of removing tinea by the combination of the medicines. The traditional Chinese medicine bath preparation used in the invention has no toxic or side effect, eliminates the side effect after hormone medicine treatment, kills germs, treats both symptoms and root causes, and fundamentally treats psoriasis, onychomycosis and other skin tinea diseases.
Drawings
Fig. 1 is a graph showing the effect of treating psoriasis in typical case 1 using the traditional Chinese medicine bath preparation of example 1;
fig. 2 is a graph showing the effect of treating onychomycosis in typical case 4 using the traditional Chinese medicine bath preparation of example 3.
Detailed Description
The invention provides a traditional Chinese medicine medicated bath preparation for treating tinea, which comprises the following raw materials in parts by weight: 1 to 15 parts of lucid ganoderma, 1 to 15 parts of honeysuckle, 1 to 15 parts of lithospermum, 1 to 15 parts of dandelion, 1 to 15 parts of coptis chinensis, 1 to 15 parts of virgate wormwood herb, 1 to 10 parts of bupleurum, 1 to 10 parts of common andrographis herb, 1 to 10 parts of cortex dictamni, 1 to 10 parts of baikal skullcap root and 1 to 10 parts of purslane.
In the traditional Chinese medicine medicated bath preparation, the ganoderma lucidum is sweet in taste and flat in nature, and can restore heart, lung, liver and kidney channels, has the effects of regulating immunity, protecting liver, detoxifying, improving blood circulation and promoting metabolism, and is a monarch drug in the prescription. The weight part of the ganoderma lucidum is more preferably 3-12 parts, still more preferably 4-10 parts. The invention is not particularly limited to the source of ganoderma lucidum, and products sold in the field can be adopted.
In the traditional Chinese medicine medicated bath preparation, the honeysuckle flower is sweet in taste and cold in nature, enters lung, heart and stomach channels, has the effects of clearing heat and detoxicating and dispelling wind and heat, and is a ministerial drug in the prescription. The weight part of the honeysuckle is more preferably 4 to 11 parts, still more preferably 5 to 10 parts. The invention has no special limitation on the source of the honeysuckle, and the product sold in the field can be adopted.
In the traditional Chinese medicine medicated bath preparation, the lithospermum has sweet and salty taste, is cold in nature, returns to heart and liver meridian, has the effects of clearing heat and cooling blood, activating blood and detoxicating, promoting eruption and removing spots, and is an adjuvant drug in the prescription. The weight part of the lithospermum is more preferably 2 to 13 parts, still more preferably 4 to 10 parts. The invention is not particularly limited to the source of lithospermum, and products sold in the field can be adopted.
In the traditional Chinese medicine medicated bath preparation, the dandelion is bitter and sweet in taste, cold in nature, enters liver and stomach channels, has the effects of clearing heat and detoxicating, detumescence and resolving masses, and inducing diuresis for treating stranguria, and is a guiding drug in the prescription. The weight part of dandelion is more preferably 3 to 14 parts, still more preferably 5 to 12 parts. The dandelion source is not particularly limited, and the dandelion source can be a product sold in the field.
In the traditional Chinese medicine medicated bath preparation, the coptis chinensis is bitter in taste, cold in nature, enters heart, spleen, stomach, liver, gall and large intestine channels, has the effects of clearing heat and drying dampness, purging intense heat and removing toxin, and is a guiding drug in the prescription. The weight part of the coptis is more preferably 4 to 11 parts, still more preferably 5 to 10 parts. The invention is not particularly limited to the source of coptis chinensis, and the product sold in the field can be adopted.
In the traditional Chinese medicine medicated bath preparation, the herba artemisiae scopariae is bitter and pungent in taste, slightly cold in nature, enters spleen, stomach, liver and gall meridian, has the effects of clearing damp-heat, and promoting bile flow to treat jaundice, and is a guiding drug in the prescription. The weight part of the capillary artemisia is more preferably 4 to 12 parts, still more preferably 6 to 10 parts. The source of the capillary artemisia is not particularly limited, and products sold in the field can be adopted.
In the traditional Chinese medicine medicated bath preparation, the bupleurum is pungent and bitter in taste and slightly cold in nature, enters liver, gall and lung channels, has the effects of dispelling and reducing fever and soothing liver and relieving depression, and is a guiding drug in a prescription. The weight part of bupleurum is more preferably 3-7 parts, and still more preferably 4-6 parts. The invention has no special limitation on the source of bupleurum, and the invention can be used by adopting products sold in the field.
In the traditional Chinese medicine medicated bath preparation, the andrographis paniculata is bitter in taste and cold in nature, enters heart, lung, large intestine and bladder channels, has the effects of clearing heat and detoxicating, cooling blood and relieving swelling, and is a guiding drug in the prescription. The weight part of the andrographis paniculata is preferably 2 to 8 parts, more preferably 3 to 7 parts. The source of the andrographis paniculata is not particularly limited, and the common andrographis paniculata can be obtained by adopting products sold in the field.
In the traditional Chinese medicine medicated bath preparation, the cortex dictamni has bitter taste and cold property, enters spleen, stomach and bladder channels, has the effects of clearing heat and drying dampness, and dispelling wind and detoxifying, and is a guiding drug in the prescription. The weight part of the cortex dictamni is more preferably 3 to 9 parts, and still more preferably 4 to 8 parts. The source of the cortex dictamni is not particularly limited, and the cortex dictamni can be obtained by using products sold in the field.
In the traditional Chinese medicine medicated bath preparation, the radix scutellariae is bitter in taste and cold in nature, enters lung, gall, spleen, large intestine and small intestine channels, has the effects of clearing heat and drying dampness, purging fire and removing toxin, stopping bleeding and preventing miscarriage, and is a guiding drug in the prescription. The weight part of the scutellaria baicalensis is more preferably 2 to 9 parts, and still more preferably 3 to 8 parts. The source of the scutellaria baicalensis is not particularly limited, and the product sold in the field can be adopted.
In the traditional Chinese medicine medicated bath preparation, the purslane has sour taste, cold property, liver and large intestine channels, has the effects of clearing heat and detoxicating, cooling blood and stopping bleeding and stopping diarrhea, and is a guiding drug in the prescription. The weight part of the purslane is more preferably 1.5 to 8 parts, and still more preferably 2 to 7 parts. The source of the purslane is not particularly limited, and products sold in the field can be adopted.
In the invention, the traditional Chinese medicine medicated bath preparation preferably further comprises white vinegar with vinegar acidity of 1% -10%. The acetic acid degree in the invention refers to the mass (g) of acetic acid in 100mL of white vinegar, for example, the acetic acid degree is 1% -10%, i.e. the mass of acetic acid in 100mL of white vinegar is 1-10 g. The source of the white vinegar is not particularly limited, and the white vinegar can be obtained by adopting products sold in the field.
The invention also provides a preparation method of the traditional Chinese medicine medicated bath preparation, which comprises the following steps:
mixing the ganoderma lucidum, the honeysuckle, the lithospermum, the dandelion, the coptis, the capillary artemisia, the bupleurum, the andrographis herb, the cortex dictamni, the scutellaria baicalensis and the purslane, grinding into powder, sieving to obtain traditional Chinese medicine powder, adding white vinegar for soaking, and taking supernatant to obtain the traditional Chinese medicine bath preparation.
In the preparation method, the traditional Chinese medicine raw materials of the traditional Chinese medicine medicated bath preparation are ground into components and sieved, the mesh number of the sieving is preferably 80-100 meshes, the release speed and the release amount of active ingredients in the traditional Chinese medicine medicated bath preparation raw materials are improved, the dosage of the traditional Chinese medicine raw materials is reduced, and the extraction time is saved. Mixing the obtained traditional Chinese medicine powder with white vinegar for soaking, wherein the soaking preferably comprises a first soaking and a second soaking, the temperature of the first soaking is preferably 20-25 ℃, more preferably 22-23 ℃, the soaking time is preferably 20-28 h, more preferably 21-27 h; the temperature of the second soaking is preferably 20-25 ℃, more preferably 22-23 ℃, and the soaking time is preferably more than 7 days; the acetic acid content of the white vinegar of the second soaking is preferably twice that of the white vinegar of the first soaking. Wherein the acetic acid content of the white vinegar is preferably 1% to 10%, more preferably 2% to 8%, and even more preferably 3% to 6%. The mass ratio of the traditional Chinese medicine powder to the white vinegar used for the first soaking is preferably 1:1-3, and more preferably 1:1.5-2.5; the mass ratio of the traditional Chinese medicine powder to the white vinegar used for the second soaking is preferably 1:1-3, and more preferably 1:1.5-2.5. By adopting the soaking mode, the invention can ensure the rapid and efficient dissolution of the active ingredients of the traditional Chinese medicine medicated bath preparation and remove the ineffective ingredients such as impurities, thereby improving the efficacy of the traditional Chinese medicine medicated bath preparation in treating tinea. In the preparation process, the dried ganoderma lucidum, honeysuckle, lithospermum, dandelion, coptis, capillary artemisia, bupleurum, andrographis paniculata, cortex dictamni, scutellaria baicalensis and purslane are preferably adopted.
The invention also provides an application of the traditional Chinese medicine medicated bath preparation or the traditional Chinese medicine medicated bath preparation prepared by the preparation method in preparing the medicine for treating the tinea.
In the present invention, the tinea cutanea preferably includes one or both of psoriasis and onychomycosis. The medicine takes the traditional Chinese medicine medicated bath preparation as an active ingredient, and simultaneously the medicine also comprises pharmaceutically acceptable auxiliary materials, for example, the auxiliary materials can comprise buffering agents, excipients, stabilizers or preservatives, such as starch, lactose, magnesium stearate, sodium sulfite, ascorbic acid and the like. The dosage form of the medicament is preferably solution, spray or emulsion and the like. The administration mode of the medicine of the invention is preferably external application, smearing or soaking. In the present invention, the dosage of the drug of the present invention may be determined by the type of the treatment disease, the severity of the disease, the administration route, the age, sex, health condition of the patient, etc., and for example, the dosage of the drug of the present invention may be 0.01 mug to 1000 mg/day per patient.
The technical solutions provided by the present invention are described in detail below with reference to examples, but they should not be construed as limiting the scope of the present invention.
Example 1
A traditional Chinese medicine medicated bath preparation for treating skin tinea comprises the following raw materials in parts by weight: 15 parts of lucid ganoderma, 15 parts of honeysuckle, 15 parts of lithospermum, 13 parts of dandelion, 10 parts of coptis chinensis, 10 parts of virgate wormwood herb, 5 parts of radix bupleuri, 5 parts of common andrographis herb, 5 parts of cortex dictamni, 5 parts of radix scutellariae and 2 parts of purslane.
The preparation method of the traditional Chinese medicine medicated bath preparation comprises the following steps:
(1) Weighing dried lucid ganoderma, honeysuckle, lithospermum, dandelion, coptis chinensis, virgate wormwood herb, bupleurum, common andrographis herb, dittany bark, baical skullcap root and purslane according to the weight parts, fully mixing, grinding into powder, and sieving with a 90-mesh sieve to obtain traditional Chinese medicine powder;
(2) Adding 2000g of white vinegar with the acetic acid content of 4% into 1000g of the traditional Chinese medicine powder obtained in the step (1), soaking the traditional Chinese medicine powder for 24 hours at 20 ℃, continuously adding 2000g of white vinegar with the acetic acid content of 8% and soaking for 168 hours at 20 ℃, filtering, and taking the supernatant to obtain the traditional Chinese medicine medicated bath preparation.
Example 2
A traditional Chinese medicine medicated bath preparation for treating skin tinea comprises the following traditional Chinese medicine raw materials in parts by weight: 5 parts of lucid ganoderma, 5 parts of honeysuckle, 10 parts of lithospermum, 5 parts of dandelion, 5 parts of coptis chinensis, 5 parts of virgate wormwood herb, 5 parts of radix bupleuri, 5 parts of common andrographis herb, 5 parts of cortex dictamni, 5 parts of radix scutellariae and 5 parts of purslane.
The preparation method of this example is the same as that of example 1 except that the weight parts of the traditional Chinese medicine raw materials of the traditional Chinese medicine medicated bath preparation are different.
Example 3
A traditional Chinese medicine medicated bath preparation for treating skin tinea comprises the following traditional Chinese medicine raw materials in parts by weight: 10 parts of lucid ganoderma, 10 parts of honeysuckle, 10 parts of lithospermum, 10 parts of dandelion, 10 parts of coptis chinensis, 10 parts of virgate wormwood herb, 10 parts of radix bupleuri, 10 parts of common andrographis herb, 10 parts of cortex dictamni, 5 parts of radix scutellariae and 5 parts of purslane.
The preparation method of this example is the same as that of example 1 except that the weight parts of the traditional Chinese medicine raw materials of the traditional Chinese medicine medicated bath preparation are different.
Example 4
A traditional Chinese medicine medicated bath preparation for treating skin tinea comprises the following traditional Chinese medicine raw materials in parts by weight: 12 parts of lucid ganoderma, 12 parts of honeysuckle, 10 parts of lithospermum, 10 parts of dandelion, 10 parts of coptis chinensis, 11 parts of virgate wormwood herb, 6 parts of radix bupleuri, 8 parts of common andrographis herb, 7 parts of cortex dictamni, 5 parts of radix scutellariae and 10 parts of purslane.
The preparation method of the traditional Chinese medicine medicated bath preparation comprises the following steps:
(1) Weighing dried lucid ganoderma, honeysuckle, lithospermum, dandelion, coptis chinensis, virgate wormwood herb, bupleurum, common andrographis herb, dittany bark, baical skullcap root and purslane according to the weight parts, fully mixing, grinding into powder, and sieving with a 100-mesh sieve to obtain traditional Chinese medicine powder;
(2) Adding 3000g of white vinegar with 3% acetic acid content into 1000g of the traditional Chinese medicine powder obtained in the step (1), soaking the traditional Chinese medicine powder for 20 hours at 25 ℃, continuously adding 2500g of white vinegar with 6% acetic acid content, soaking for 168 hours at 25 ℃, filtering, and taking supernatant to obtain the traditional Chinese medicine medicated bath preparation.
Example 5
A traditional Chinese medicine medicated bath preparation for treating skin tinea comprises the following traditional Chinese medicine raw materials in parts by weight: 3 parts of lucid ganoderma, 4 parts of honeysuckle, 2 parts of lithospermum, 2 parts of dandelion, 1 part of coptis chinensis, 3 parts of virgate wormwood herb, 2 parts of bupleurum, 1 part of common andrographis herb, 2 parts of cortex dictamni, 1 part of baical skullcap root and 2 parts of purslane.
The preparation method of the traditional Chinese medicine medicated bath preparation comprises the following steps:
(1) Weighing dried lucid ganoderma, honeysuckle, lithospermum, dandelion, coptis chinensis, virgate wormwood herb, bupleurum, common andrographis herb, dittany bark, baical skullcap root and purslane according to the weight parts, fully mixing, grinding into powder, and sieving with a 80-mesh sieve to obtain traditional Chinese medicine powder;
(2) Adding 1500g of white vinegar with 5% acetic acid content into 1000g of the traditional Chinese medicine powder obtained in the step (1), soaking the traditional Chinese medicine powder for 28h at 20 ℃, continuously adding 1000g of white vinegar with 10% acetic acid content, soaking for 168h at 20 ℃, filtering, and taking supernatant to obtain the traditional Chinese medicine medicated bath preparation.
Typical cases:
1. zhao Mou women, 44 years old, complain about psoriasis for more than 10 years, and seek medical attention to be ineffective. The erythema on both sides of the arm is obvious, and bleeding is caused after the scales are desquamated, so that the itching is odd. The stock solution of the traditional Chinese medicine medicated bath preparation prepared in the embodiment 1 is diluted and soaked for three treatment courses in a ratio of 1:30, one treatment course is 28 days, soaking is carried out for 1 time a day, the body surface wounds are healed, the skin is basically improved, the psoriasis is healed completely, and the psoriasis does not relapse after one year (see figure 1 for details).
2. Wang Mou female, 28 years old, complain about psoriasis for 5 years, use a large amount of hormone medicines to suppress tinea, treat the symptoms and the root cause, and burst in a large area at the stage of low immunity. The stock solution of the traditional Chinese medicine medicated bath preparation in the embodiment 2 is diluted and soaked for three treatment courses in a ratio of 1:30, one treatment course is 28 days, soaking is carried out for 1 time a day, skin damage is completely disappeared, normal health condition of skin is recovered, and no recurrence is caused after one year of follow-up.
3. Jiang Mou men, 50 years old, complain about onychomycosis for more than 6 years, and fungi invade so that the nail plate becomes brittle and fragile, and the nail plate becomes grey and opaque to the naked eye. The stock solution of the traditional Chinese medicine medicated bath preparation in the embodiment 3 is used for being smeared for a treatment course twice in the morning and at the evening, the treatment course is 28 days, fungi are removed, the disease nails recover from health status, and no recurrence occurs in two years following diagnosis.
4. Liu Mou when female, 60 years old, complain about onychomycosis for more than 15 years, fungi invade the horny layer of the part of the far-end nail at the beginning, gradually cause the bottom surface of the deck to be invaded, and the color of the deck gradually declines along with the invasion aggravation, and the deck becomes fragile and fragile to form broken nails. After two treatment courses are applied with the stock solution of the traditional Chinese medicine bath preparation in the embodiment 3, one treatment course is 28 days, the stock solution is applied for 2 times a day, fungi are removed, healthy new nails grow along with metabolism, and the whole state of nails is good (see figure 2 for details).
The foregoing is merely a preferred embodiment of the present invention and it should be noted that modifications and adaptations to those skilled in the art may be made without departing from the principles of the present invention, which are intended to be comprehended within the scope of the present invention.
Claims (10)
1. The traditional Chinese medicine medicated bath preparation for treating the skin tinea is characterized by comprising the following raw materials in parts by weight: 1 to 15 parts of lucid ganoderma, 1 to 15 parts of honeysuckle, 1 to 15 parts of lithospermum, 1 to 15 parts of dandelion, 1 to 15 parts of coptis chinensis, 1 to 15 parts of virgate wormwood herb, 1 to 10 parts of bupleurum, 1 to 10 parts of common andrographis herb, 1 to 10 parts of cortex dictamni, 1 to 10 parts of baikal skullcap root and 1 to 10 parts of purslane.
2. The traditional Chinese medicine medicated bath preparation according to claim 1, which comprises the following raw materials in parts by weight: 3 to 12 parts of lucid ganoderma, 4 to 11 parts of honeysuckle, 2 to 13 parts of lithospermum, 3 to 14 parts of dandelion, 4 to 11 parts of coptis chinensis, 4 to 12 parts of virgate wormwood herb, 3 to 7 parts of bupleurum, 2 to 8 parts of common andrographis herb, 3 to 9 parts of cortex dictamni, 2 to 9 parts of baical skullcap root and 1.5 to 8 parts of purslane.
3. The traditional Chinese medicine medicated bath preparation according to claim 1 or 2, further comprising white vinegar with vinegar acidity of 1% -10%.
4. A method for preparing the traditional Chinese medicine bath preparation according to any one of claims 1 to 3, which is characterized by comprising the following steps:
mixing the ganoderma lucidum, the honeysuckle, the lithospermum, the dandelion, the coptis, the capillary artemisia, the bupleurum, the andrographis herb, the cortex dictamni, the scutellaria baicalensis and the purslane, grinding into powder, sieving to obtain traditional Chinese medicine powder, adding white vinegar for soaking, and taking supernatant to obtain the traditional Chinese medicine bath preparation.
5. The method according to claim 4, wherein the soaking comprises a first soaking and a second soaking, the temperature of the first soaking is 20-25 ℃ and the soaking time is 20-28 h; the temperature of the second soaking is 20-25 ℃, and the soaking time is more than 7 days; the acetic acid degree of the white vinegar soaked for the second time is twice that of the white vinegar soaked for the first time.
6. The method according to claim 4, wherein the white vinegar has an acidity of 1% to 10%.
7. The method according to claim 4, wherein the mesh number of the sieve is 80 to 100 mesh.
8. The preparation method according to claim 5, wherein the mass ratio of the traditional Chinese medicine powder to the white vinegar used for the first soaking is 1:1-3; the mass ratio of the traditional Chinese medicine powder to the white vinegar used for the second soaking is 1:1-3.
9. Use of a Chinese medicinal bath preparation according to any one of claims 1 to 3 or a Chinese medicinal bath preparation prepared by a preparation method according to any one of claims 4 to 8 in the preparation of a medicament for treating tinea.
10. The use according to claim 9, wherein the tinea comprises one or both of psoriasis and onychomycosis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310417016.1A CN116211923A (en) | 2023-04-18 | 2023-04-18 | Traditional Chinese medicine medicated bath preparation for treating tinea, and preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310417016.1A CN116211923A (en) | 2023-04-18 | 2023-04-18 | Traditional Chinese medicine medicated bath preparation for treating tinea, and preparation method and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116211923A true CN116211923A (en) | 2023-06-06 |
Family
ID=86582853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310417016.1A Pending CN116211923A (en) | 2023-04-18 | 2023-04-18 | Traditional Chinese medicine medicated bath preparation for treating tinea, and preparation method and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116211923A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103230483A (en) * | 2013-04-28 | 2013-08-07 | 董福明 | Traditional Chinese medicine preparation for treating beriberi |
| CN104147188A (en) * | 2014-07-11 | 2014-11-19 | 李开庆 | Sore ulcer and mange wine and using method thereof |
| CN104258003A (en) * | 2014-09-10 | 2015-01-07 | 欧阳铭浩 | Preparation method of spray for treating beriberi |
| CN106138376A (en) * | 2016-08-16 | 2016-11-23 | 余桂火 | A kind of Chinese medicine preparation treating psoriasis eczema tinea pedis carbuncle sore and preparation method thereof |
-
2023
- 2023-04-18 CN CN202310417016.1A patent/CN116211923A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103230483A (en) * | 2013-04-28 | 2013-08-07 | 董福明 | Traditional Chinese medicine preparation for treating beriberi |
| CN104147188A (en) * | 2014-07-11 | 2014-11-19 | 李开庆 | Sore ulcer and mange wine and using method thereof |
| CN104258003A (en) * | 2014-09-10 | 2015-01-07 | 欧阳铭浩 | Preparation method of spray for treating beriberi |
| CN106138376A (en) * | 2016-08-16 | 2016-11-23 | 余桂火 | A kind of Chinese medicine preparation treating psoriasis eczema tinea pedis carbuncle sore and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 菌物界: "灵芝辅助治疗皮肤病——牛皮癣", pages 2, Retrieved from the Internet <URL:https://mp.weixin.qq.com/s?__biz=MzA4Mjk3MDcyOA==&mid=2478490827&idx=1&sn=c282dd157221f42f2e0d6cc2bd73aa55&chksm=89b3f5cc%E2%80%A6%201/6%20%E7%81%B5%E8%8A%9D%E8%BE%85%E5%8A%A9%E6%B2%BB%E7%96%97%E7%9A%AE%E8%82%A4%E7%97%85%20%E2%80%94%E2%80%94%20%E7%89%9B%E7%9A%AE%E7%99%A3> * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11571452B2 (en) | Method of treating a skin wound with a liquid-state topical pharmaceutical composition | |
| CN104825941B (en) | A kind of herbal composite and preparation method thereof for treating tinea pedis | |
| CN101297814A (en) | Emulsifiable paste for curing acne and preparation thereof | |
| CN106822321B (en) | Application of Curcuma water of traumatology in preparing medicine for treating keratosis pilaris | |
| CN116211923A (en) | Traditional Chinese medicine medicated bath preparation for treating tinea, and preparation method and application thereof | |
| CN113730341A (en) | Bitong gel and using method and preparation method thereof | |
| CN108159360B (en) | Traditional Chinese medicine hoof care cream for cow hoof injury and preparation method thereof | |
| CN105031596A (en) | Ointment for treating nummular eczema and preparing method thereof | |
| CN104306707A (en) | Medicament composition for treating bedsore | |
| CN114288366B (en) | Medicated bath composition for preventing and treating skin diseases of bedridden patients and preparation method thereof | |
| CN109464573A (en) | For treating diabetes chronic ulcer, the Chinese medicine oil yarn of gangrene and method | |
| CN108619431A (en) | A kind of Chinese medicine composition and preparation method thereof for treating gout | |
| CN108420980A (en) | It is a kind of treat skin injury, bacterium infection antibacterial ointment and preparation method thereof | |
| CN116036168B (en) | Traditional Chinese medicine composition for treating phlebitis and application thereof | |
| RU2782695C1 (en) | Composition for external use "septisol" | |
| CN110403995B (en) | Traditional Chinese medicine composition for treating superficial phlebitis and preparation, use methods and application thereof | |
| CN107029072A (en) | A kind of Hibisci Paste with antiinflammatory action | |
| CN101869578B (en) | External liniment for drawing pus out and diminishing inflammation | |
| CN106729672A (en) | A kind of composition for treating upper respiratory tract mucositis and its application | |
| CN115429838A (en) | Traditional Chinese medicine for treating rhinitis and red swelling and pruritus of skin and preparation method thereof | |
| CN104906217A (en) | Traditional Chinese medicine ointment for treating acute catarrhal conjunctivitis and preparation method thereof | |
| CN105194289B (en) | It is a kind of to treat dermopathic external drug and preparation method thereof | |
| CN114796178A (en) | Potential therapeutic use of L-glutamine for alleviating bungarus fasciatus | |
| CN117257871A (en) | Traditional Chinese medicine formula for treating herpes zoster | |
| CN118121537A (en) | Efficient antibacterial gynecological gel and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |