CN1161863A - Medical supersonic couplant - Google Patents
Medical supersonic couplant Download PDFInfo
- Publication number
- CN1161863A CN1161863A CN 97101411 CN97101411A CN1161863A CN 1161863 A CN1161863 A CN 1161863A CN 97101411 CN97101411 CN 97101411 CN 97101411 A CN97101411 A CN 97101411A CN 1161863 A CN1161863 A CN 1161863A
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- China
- Prior art keywords
- ultrasonic
- coupling agent
- agent
- solvent
- antiseptic
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
The medical ultrasonic coupling agent for clinical application is composed of anchoring agent 23g, lubricating agent 200 ml, solvent 800 ml, antiseptic 2g, perfuming agent 0.1 ml and toner 0.5 ml. Its formula is simple, easy to produce, raw material is rich, cost is low, application effect is good, and said invented coupling agent is stable in properties, doesn't damage ultrasonic transducer probe and is non-corrosive, possesses good coupling effect with skin, and can make image clear and sharp.
Description
The present invention relates to a kind of medical ultrasonic coupling agent of using when ultrasonic examination.
Couplant is the essential medium of ultrasonic diagnosis, in order to eliminate the air film between skin and probe, avoids ultrasonic reflection to make it penetrate tissue and realizes diagnosis.Along with ultrasonic examination the popularizing of town and country, the needs of couplant are increased day by day.Present domestic main employing import couplant, cost an arm and a leg, be difficult to generally adopt, many medical institutions suffer from idealless couplant, often the couplant that contains lipid or ethanol with white oil or preparation voluntarily substitutes, this not only influences the ultrasonic image effect, and causes the top layer damage of ultrasonic instrument probe, has influenced result of use and life-span greatly.
Purpose of the present invention is exactly at above-mentioned situation, in conjunction with the actual needs in the ultrasonic diagnosis, and provides a kind of medical ultrasonic coupling agent of the new clinical practice satisfied.
The object of the present invention is achieved like this adds lubricant 200ml in the 800ml solvent, viscosifier 23 grams, antiseptic 2 grams, deodorant tune 0.1ml, toner 0.5ml, amount can or reduce each composition by the corresponding increase of dosage requirement as required, but its dosage ratio will keep corresponding relation.
Its prescription of the present invention is simple, and cost is low, and abundant raw material is economized on the use of funds or foreign exchange, is easy to produce and popularize, and promotes the development of medical industry.
Describe concrete condition of the present invention in detail below in conjunction with embodiment.
The present invention is made of following component:
Viscosifier 23 grams
Lubricant 200ml
Solvent 800ml
Antiseptic 2 grams
Deodorant tune 0.1ml
In the above-mentioned component of toner 0.5ml; viscosifier adopt the Shanghai chemical reagent to adopt for the sodium carboxymethyl cellulose of standing; the medicinal glycerin that lubricant adopts Xiamen Cod-liver Oil Factory to produce; solvent adopts distilled water, and (deionization is two to be steamed; all can make by oneself or purchase); the AR type sodium benzoate that antiseptic adopts development chemical plant, Shanghai to produce, the industrial goods jasmin essence that deodorant tune adopts Shanghai essence factory to produce, biological dye's 2% U.S. blue solution that toner adopts Shanghai reagent three factories to produce.
Its production method is:
(1) earlier Sodium Tvlose was sterilized 2 hours through Burdick lamp, standby.
(2) in the 1000ml beaker, add 700ml distilled water and 200ml glycerol under the room temperature, add sodium carboxymethyl cellulose 23g behind the stirring and evenly mixing gradually, ceaselessly stir, be uniformly dispersed until Sodium Tvlose.
(3) add 2% sodium benzoate aqueous solution 100ml, after continuing to stir, add essence again, 2% is U.S. blue, stirs.
(4) stop to stir after, beaker is placed in the ultrasonic degas groove, drive minute bubbles out of with ultrasound wave.As do not have the ultrasonic degas device, and can be in 70--80 ℃ of heating in water bath to there not being bubble, the goods of also can being satisfied with.
Component amount of the present invention is any corresponding increase of proportioning or minimizing on request, such as being example with 8000ml solvent (distilled water), in water as solvent add glycerol 2000ml at 8000ml to distill by the dosage required amount, sodium benzoate 20 grams, sodium carboxymethyl cellulose 230 grams, essence 1ml, 2% U.S. blue solution 5ml.Under this dosage, its preparation method is:
In stirring down, sodium benzoate is dissolved in the distilled water, add glycerol, mixing then adds sodium carboxymethyl cellulose gradually on a small quantity, is stirred to be uniformly dispersed, and adds essence, U.S. blue again, continues stirring and evenly mixing, and standing over night is eliminated bubble, and sealed packaging is standby.As after not having motor stirrer and sodium benzoate can being dissolved in distilled water, sodium carboxymethyl cellulose evenly is sprinkling upon on the water surface covered container lid; Left standstill 3-4 days, and treated to add after the complete swelling glycerol, essence and Mei Lan in water, stir by hand, standing over night is overflowed behind the bubble can packing standby.Can increase and decrease the consumption of distilled water in the preparation process according to the variation of season and temperature, the viscosity of adjusting goods is suitable.
Performance of the present invention and clinical effectiveness:
1, proterties: this product is neutral water soluble gum body preparation, modest viscosity (600-1000 centipoise), and homogeneous, the light orchid of outward appearance is transparent, without bubble, fragrant odour.
2, acoustical behavior: through Acoustical Inst., Chinese Academy of Sciences's test, in 26 ℃ of room temperatures, record density 1.0g/cm with the 1MHz wide-band transducer3, velocity of sound 1540m/s, ultrasonic attenuation 0.06dB/cmm, acoustic impedance 1.54 * 105g/
cm
2S, expert's conclusion, this couplant is good with human body soft tissue acoustic impedance coupling, and acoustic attenuation is little, the suitable medical ultrasonic coupling agent of doing of its acoustical behavior.
3, clinical effectiveness: through Henan Prov. Tumour Hospital, province the People's Hospital, province's epidemic prevention station, the province tuberculosis hospital, unit clinic trial such as two sand hospitals of First Machinery Industry Department show: (1) this couplant is non-stimulated to skin, nonhazardous, not dirty medicated clothing, attaching power are low, wiping easily.(2) do not contain lipid and alcohol type material, to probe (ultrasonic transducer) not damaged, nothing corrosion.(3) good to the ultrasonic instrument probe with the skin coupling, there is not the voice phenomenon of leakage, probe promotes freely, lubricity is good.(4) surpassed image and to take the photograph sheet clear, no virtual image and image take off the mistake phenomenon, are applicable to the diagnostic ultrasonic equipment that various direct detections are used.(5) this product good stability was deposited 1 year, did not have degraded, did not have corruption, and nothing is gone mouldy.(6) raw material is easy to get, and preparation technology and equipment are simple, and low production cost is easy to prepare voluntarily and apply.
The present invention compares with domestic and international product: (871 couplants are product of the present invention in the table)
| Title | ??PH | Density g/cm 3 | Velocity of sound m/s | Ultrasonic attenuation dB/cmM | Ultrasonic impedance g/cm 2·S |
| 871 couplants | ??7.0 | ????1.0 | ??1540 | ????0.06 | ?1.54×10 6 |
| U.S. A-100 | ??7.0 | ????1.01 | ??1600 | ????0.043 | ?1.62×10 5 |
| Japan--100 | ??7.1 | ????1.03 | ??1510 | ????0.073 | ?1.55×10 5 |
| Tianjin GTY | ??7.0 | ????1.01 | ??1516 | ????0.05 | ?1.53×10 5 |
As can be seen from the table, the present invention meets or exceeds like product fully, for couplant opens up a new way, has huge economic and social benefit, will make contribution energetically for the popularization and application of medical ultrasound diagnosis.
Claims (3)
1, a kind of medical ultrasonic coupling agent is characterized in that it being to be made of component viscosifier 23 grams, lubricant 200ml, solvent 800ml, antiseptic 2 grams, deodorant tune 0.1ml, toner 0.5ml.
2, medical ultrasonic coupling agent according to claim 1 is characterized in that said viscosifier are that sodium carboxymethyl cellulose, lubricant are that glycerol, solvent are that distilled water, antiseptic are that sodium benzoate, deodorant tune are that jasmin essence, toner are 2% U.S. blue solution.
3, medical ultrasonic coupling agent according to claim 1 and 2 is characterized in that said each component amount can be by corresponding any expansion of proportioning or minimizing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97101411 CN1161863A (en) | 1997-01-17 | 1997-01-17 | Medical supersonic couplant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97101411 CN1161863A (en) | 1997-01-17 | 1997-01-17 | Medical supersonic couplant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1161863A true CN1161863A (en) | 1997-10-15 |
Family
ID=5165720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 97101411 Pending CN1161863A (en) | 1997-01-17 | 1997-01-17 | Medical supersonic couplant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1161863A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101195703B (en) * | 2006-09-19 | 2012-05-30 | 二重集团（德阳）重型装备股份有限公司 | Couplant for fault detection and method for producing the same |
| CN106632904A (en) * | 2016-12-19 | 2017-05-10 | 钦州市钦南区科学技术情报研究所 | Ultrasonic coupling medium material and preparation method thereof |
| CN107596392A (en) * | 2017-10-09 | 2018-01-19 | 南京图艾生物医药科技有限公司 | Medical ultrasonic coupling agent |
| CN108030934A (en) * | 2017-12-22 | 2018-05-15 | 重庆医科大学附属永川医院 | A kind of aqua type medical ultrasonic coupling agent and preparation method thereof and application method |
-
1997
- 1997-01-17 CN CN 97101411 patent/CN1161863A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101195703B (en) * | 2006-09-19 | 2012-05-30 | 二重集团（德阳）重型装备股份有限公司 | Couplant for fault detection and method for producing the same |
| CN106632904A (en) * | 2016-12-19 | 2017-05-10 | 钦州市钦南区科学技术情报研究所 | Ultrasonic coupling medium material and preparation method thereof |
| CN107596392A (en) * | 2017-10-09 | 2018-01-19 | 南京图艾生物医药科技有限公司 | Medical ultrasonic coupling agent |
| CN108030934A (en) * | 2017-12-22 | 2018-05-15 | 重庆医科大学附属永川医院 | A kind of aqua type medical ultrasonic coupling agent and preparation method thereof and application method |
| CN108030934B (en) * | 2017-12-22 | 2021-05-11 | 重庆医科大学附属永川医院 | Water-based medical ultrasonic coupling agent and preparation method and use method thereof |
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| SE01 | Entry into force of request for substantive examination | ||
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| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |