CN116173409A - Percutaneous electrical stimulation system synchronous with respiration - Google Patents

Percutaneous electrical stimulation system synchronous with respiration Download PDF

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Publication number
CN116173409A
CN116173409A CN202310201843.7A CN202310201843A CN116173409A CN 116173409 A CN116173409 A CN 116173409A CN 202310201843 A CN202310201843 A CN 202310201843A CN 116173409 A CN116173409 A CN 116173409A
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respiration
respiratory
signal waveform
color
transceiver
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CN116173409B (en
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郭磊
麻利义
陈建峰
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MEDKINETIC Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0816Measuring devices for examining respiratory frequency
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/486Bio-feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/002Using electric currents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/3603Control systems
    • A61N1/36031Control systems using physiological parameters for adjustment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/3603Control systems
    • A61N1/36034Control systems specified by the stimulation parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2230/00Measuring physical parameters of the user
    • A61H2230/40Respiratory characteristics
    • A61H2230/42Rate
    • A61H2230/425Rate used as a control parameter for the apparatus

Abstract

The invention discloses a percutaneous electrical stimulation system synchronous with respiration, which is used for synchronously combining respiratory frequency and nerve regulation frequency and comprises a respiratory signal recorder, a percutaneous nerve electrical stimulator and a terminal controller, wherein the percutaneous nerve electrical stimulator is arranged at a part of a human body needing electrical stimulation and comprises an electrical pulse generator and a first transceiver, and the electrical pulse generator sends current pulses to the part according to a preset electrical stimulation period so as to regulate the nerve of the part. The percutaneous electrical stimulation system synchronous with respiration disclosed by the invention synchronously combines the respiration frequency with the output pulse frequency regulated and controlled by nerves, and encourages a user to breathe regularly according to the pulse stimulation frequency by means of biofeedback, so that the effect is enhanced.

Description

Percutaneous electrical stimulation system synchronous with respiration
Technical Field
The invention belongs to the technical field of electrical stimulation equipment, and particularly relates to a percutaneous electrical stimulation system synchronous with breathing.
Background
The nerve regulation method is to stimulate the peripheral acupoints of the nerve by applying current pulse to the relevant medical equipment to increase the activity of vagus nerve and treat gastrointestinal motility, inflammation and pain.
Studies have shown that regular low frequency deep breathing can also enhance vagal activity. Many health problems are associated with parasympathetic hypoxia.
Therefore, the combination of the respiratory rate of deep breathing and the neuromodulation rate can enhance the activity of the vagus nerve to a greater extent.
Disclosure of Invention
The main purpose of the invention is to provide a percutaneous electric stimulation system synchronous with respiration, which synchronously combines the respiration frequency with the output pulse frequency regulated by nerves, and encourages users to breathe regularly according to the pulse stimulation frequency by means of biofeedback so as to enhance the effect.
To achieve the above object, the present invention provides a respiratory-synchronized percutaneous electrical stimulation system for synchronously combining a (deep) respiratory frequency and a nerve regulation frequency, comprising a respiratory signal recorder, a percutaneous nerve stimulator and a terminal controller, wherein:
the percutaneous nerve electric stimulator is arranged at a part (such as a Zusanli acupoint) of a human body needing electric stimulation, comprises an electric pulse generator and a first transceiver (including wired and wireless, preferably wireless transmission), wherein the electric pulse generator sends current pulses to the part (through an output electrode and according to a preset electric stimulation period) so as to carry out nerve regulation on the part, and the first transceiver transmits pulse (square wave) signals (i.e. pulse train rhythm and nerve regulation frequency) of the current pulses to the terminal controller so that the terminal controller converts the square wave signals of the current pulses into corresponding electric stimulation sine waves and displays the corresponding electric stimulation sine waves in real time and then prompts the user to carry out deep breathing action according to the displayed electric stimulation sine waves;
the respiration signal recorder is arranged at a respiration detection part (preferably near the chest diaphragm) of a human body of a user and comprises a respiration signal sensor, a respiration signal processor and a second transceiver (comprising wired and wireless, preferably wireless transmission), wherein the respiration signal sensor acquires the respiration signal (namely the respiration frequency) of the user in real time and processes the respiration signal (converts an electric signal into a digital signal) through the respiration signal processor, and the second transceiver transmits the processed respiration signal to the terminal controller so that the terminal controller generates a corresponding respiration signal waveform and displays the corresponding respiration signal waveform in real time;
the terminal controller synchronously displays the acquired electric stimulation sine wave and the respiratory signal waveform on the same coordinate axis interface, so that the synchronous degree of the current respiratory signal waveform and the electric stimulation sine wave is reflected, and respiratory feedback (biofeedback instruction/information) is carried out according to the synchronous degree, so that the respiratory signal waveform is within the allowable error of the electric stimulation sine wave.
As a further preferable embodiment of the above-described embodiment, for the respiratory feedback, the degree of synchronization is displayed by color, wherein:
in the interface of the same coordinate axis, static color display (namely, the color is kept unchanged, preferably black or gray and other darkness colors) is carried out on the electric stimulation sine wave, dynamic color display is carried out on the breathing signal waveform according to the synchronous calculation result, and the dynamic color is divided into a plurality of color areas, wherein the dynamic color is divided into a plurality of color areas;
if the respiratory signal waveform within a preset time period (for example, within 1 second) and the electric stimulation sine wave within a time period are in a first synchronization degree (that is, the respiratory signal waveform is within an allowable error of the electric stimulation sine wave and the synchronization degree is higher), displaying the current respiratory signal waveform as a first color region, and displaying a specific corresponding color in the first color region according to the high or low of the first synchronization degree (for example, the first color region is blue, the synchronization degree reaches 80% light blue, and the synchronization degree reaches 100% dark blue for dynamic color change display), so as to perform first respiratory feedback (for example, prompting the user to keep the respiratory frequency through voice);
if the respiration signal waveform within the preset time period (for example, within 1 second) and the electrical stimulation sine wave within the time period are in the second synchronization degree (that is, the respiration signal waveform is within the allowable error of the electrical stimulation sine wave, but the synchronization degree is lower), the current respiration signal waveform is displayed as a second color region, and a specific corresponding color in the second color region is displayed according to the second synchronization degree (for example, the second color region is green, the synchronization degree reaches 50% of light green, and the synchronization degree reaches 70% of dark green, so as to perform dynamic color change display), so that the second respiration feedback (for example, the user is prompted by voice to keep slightly accelerating or slowing down the respiration frequency, and then to synchronize with the electrical stimulation sine wave to a greater extent);
if the respiratory signal waveform within the preset time period (for example, within 1 second) and the electric stimulation sine wave within the time period are in the third synchronization degree (that is, the respiratory signal waveform is not within the allowable error of the electric stimulation sine wave and the synchronization degree is low), the current respiratory signal waveform is displayed as a third color area, a specific corresponding color in the third color area is displayed according to the height of the third synchronization degree (for example, the third color area is red, the synchronization degree reaches 30% of light red, the synchronization degree reaches 10% of dark red, so as to perform dynamic color change display), and therefore third respiratory feedback (for example, the user is prompted by voice to accelerate or slow down the respiratory frequency, and then the current respiratory signal waveform is synchronized with the electric stimulation sine wave to a greater extent).
As a further preferable technical scheme of the technical scheme, the synchronization degree of the respiration signal waveform and the electric stimulation sine wave is obtained according to the following formula:
Figure BDA0004109302610000041
wherein s is i Representing the corresponding value of the respiration signal waveform, f i Representing the value corresponding to the electro-stimulation sine wave (vs f i Sum s i Normalization is performed so that the values of both are between-1 and 1).
As a further preferable aspect of the foregoing technical solution, the terminal controller includes a third transceiver and a processor, a first input terminal of the third transceiver is in data communication with the first transceiver to obtain a pulse signal, a second input terminal of the third transceiver is in data communication with the second transceiver to obtain a respiration signal, and an output terminal of the third transceiver transmits the pulse signal and the respiration signal to the processor, respectively, to obtain an electrical stimulation sine wave and a respiration signal waveform, respectively.
Drawings
Fig. 1 is a schematic diagram of the structure of a respiratory synchronized transcutaneous electrical stimulation system of the present invention.
Fig. 2 is a schematic flow diagram of a respiratory synchronized transcutaneous electrical stimulation system of the present invention.
Fig. 3 is a schematic diagram of the current pulses and corresponding electrical stimulation sine waves of the respiratory synchronized transcutaneous electrical stimulation system of the present invention.
Fig. 4 is a schematic diagram of the electrical stimulation sine wave and respiratory signal waveforms of the respiratory synchronized transcutaneous electrical stimulation system of the present invention.
Detailed Description
The following description is presented to enable one of ordinary skill in the art to make and use the invention. The preferred embodiments in the following description are by way of example only and other obvious variations will occur to those skilled in the art. The basic principles of the invention defined in the following description may be applied to other embodiments, variations, modifications, equivalents, and other technical solutions without departing from the spirit and scope of the invention.
In a preferred embodiment of the present invention, it should be noted by those skilled in the art that deep breathing and vagus nerves and the like, to which the present invention relates, may be considered prior art.
Preferred embodiments.
As shown in fig. 1-4, the invention discloses a respiratory synchronous percutaneous electrical stimulation system, which is used for synchronously combining a (deep) respiratory frequency and a nerve regulation frequency, and comprises a respiratory signal recorder, a percutaneous nerve electrical stimulator and a terminal controller, wherein:
the percutaneous nerve electric stimulator is arranged at a part (such as a Zusanli acupoint) of a human body needing electric stimulation, comprises an electric pulse generator and a first transceiver (including wire and wireless, preferably wireless transmission), wherein the electric pulse generator sends current pulses to the part (through an output patch electrode and according to a preset electric stimulation period) so as to carry out nerve regulation on the part, and the first transceiver transmits pulse (square wave) signals (i.e. pulse train rhythms and nerve regulation frequency) of the current pulses to the terminal controller so that the terminal controller converts the square wave signals of the current pulses into corresponding electric stimulation sine waves and carries out real-time display, and then prompts the user to carry out deep breathing action according to the displayed electric stimulation sine waves;
the respiration signal recorder is arranged at a respiration detection part (preferably near the chest diaphragm) of a human body of a user and comprises a respiration signal sensor, a respiration signal processor and a second transceiver (comprising wired and wireless, preferably wireless transmission), wherein the respiration signal sensor acquires the respiration signal (namely the respiration frequency) of the user in real time and processes the respiration signal (converts an electric signal into a digital signal) through the respiration signal processor, and the second transceiver transmits the processed respiration signal to the terminal controller so that the terminal controller generates a corresponding respiration signal waveform and displays the corresponding respiration signal waveform in real time;
the terminal controller synchronously displays the acquired electric stimulation sine wave and the respiratory signal waveform on the same coordinate axis interface, so as to reflect the synchronous degree of the current respiratory signal waveform and the electric stimulation sine wave and carry out respiratory feedback (biofeedback instruction/information) according to the synchronous degree, so that the respiratory signal waveform is within the allowable error of the electric stimulation sine wave (the terminal controller displays the rhythm of output pulse, namely the sine waveform, to instruct a user to carry out deep respiration according to the rhythm, and simultaneously displays the respiratory signal waveform acquired by a respiratory recorder beside the pulse rhythm.
Specifically, for respiratory feedback, the degree of synchronization is displayed by color, wherein:
in the interface of the same coordinate axis, static color display (namely, the color is kept unchanged, preferably black or gray and other darkness colors) is carried out on the electric stimulation sine wave, dynamic color display is carried out on the breathing signal waveform according to the synchronous calculation result, and the dynamic color is divided into a plurality of color areas, wherein the dynamic color is divided into a plurality of color areas;
if the respiratory signal waveform within a preset time period (for example, within 1 second) and the electric stimulation sine wave within a time period are in a first synchronization degree (that is, the respiratory signal waveform is within an allowable error of the electric stimulation sine wave and the synchronization degree is higher), displaying the current respiratory signal waveform as a first color region, and displaying a specific corresponding color in the first color region according to the high or low of the first synchronization degree (for example, the first color region is blue, the synchronization degree reaches 80% light blue, and the synchronization degree reaches 100% dark blue for dynamic color change display), so as to perform first respiratory feedback (for example, prompting the user to keep the respiratory frequency through voice);
if the respiration signal waveform within the preset time period (for example, within 1 second) and the electrical stimulation sine wave within the time period are in the second synchronization degree (that is, the respiration signal waveform is within the allowable error of the electrical stimulation sine wave, but the synchronization degree is lower), the current respiration signal waveform is displayed as a second color region, and a specific corresponding color in the second color region is displayed according to the second synchronization degree (for example, the second color region is green, the synchronization degree reaches 50% of light green, and the synchronization degree reaches 70% of dark green, so as to perform dynamic color change display), so that the second respiration feedback (for example, the user is prompted by voice to keep slightly accelerating or slowing down the respiration frequency, and then to synchronize with the electrical stimulation sine wave to a greater extent);
if the respiratory signal waveform within the preset time period (for example, within 1 second) and the electric stimulation sine wave within the time period are in the third synchronization degree (that is, the respiratory signal waveform is not within the allowable error of the electric stimulation sine wave and the synchronization degree is low), the current respiratory signal waveform is displayed as a third color area, a specific corresponding color in the third color area is displayed according to the height of the third synchronization degree (for example, the third color area is red, the synchronization degree reaches 30% of light red, the synchronization degree reaches 10% of dark red, so as to perform dynamic color change display), and therefore third respiratory feedback (for example, the user is prompted by voice to accelerate or slow down the respiratory frequency, and then the current respiratory signal waveform is synchronized with the electric stimulation sine wave to a greater extent).
More specifically, the degree of synchronization of the respiratory signal waveform with the electrical stimulation sine wave is obtained according to the following formula:
Figure BDA0004109302610000071
wherein s is i Representing the corresponding value of the respiration signal waveform, f i Representing the value corresponding to the electro-stimulation sine wave (vs f i Sum s i Normalization is performed so that the values of both are between-1 and 1).
Further, the terminal controller comprises a third transceiver and a processor, wherein a first input end of the third transceiver is in data communication with the first transceiver so as to acquire pulse signals, a second input end of the third transceiver is in data communication with the second transceiver so as to acquire respiratory signals, and an output end of the third transceiver respectively transmits the pulse signals and the respiratory signals to the processor so as to acquire electric stimulation sine waves and respiratory signal waveforms.
Preferably, the intensity of parasympathetic activity can be calculated from the heart rate variability before and after stimulation and respiration, so that the effect of stimulation and respiration is known.
It should be noted that technical features such as deep breathing and vagus nerve related to the present application should be considered as the prior art, and specific structures, working principles, and control modes and spatial arrangement related to the technical features may be conventional in the art, and should not be considered as the invention point of the present application, which is not further specifically described in detail.
Modifications of the embodiments described above, or equivalents of some of the features may be made by those skilled in the art, and any modifications, equivalents, improvements or etc. within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims (4)

1. A respiratory synchronized percutaneous electrical stimulation system for synchronizing the respiratory rate and the neuromodulation frequency, comprising a respiratory signal recorder, a percutaneous electrical nerve stimulator, and a terminal controller, wherein:
the percutaneous nerve electric stimulator is arranged at a part of a human body needing electric stimulation and comprises an electric pulse generator and a first transceiver, wherein the electric pulse generator sends current pulses to the part according to a preset electric stimulation period so as to carry out nerve regulation and control on the part, and the first transceiver transmits pulse signals of the current pulses to the terminal controller so that the terminal controller converts square wave signals of the current pulses into corresponding electric stimulation sine waves and displays the corresponding electric stimulation sine waves in real time, and then prompts a user to carry out deep breathing actions according to the displayed electric stimulation sine waves;
the respiration signal recorder is arranged at a respiration detection part of a human body and comprises a respiration signal sensor, a respiration signal processor and a second transceiver, wherein the respiration signal sensor collects respiration signals of a user in real time and processes the respiration signals through the respiration signal processor, and the second transceiver transmits the processed respiration signals to the terminal controller so that the terminal controller can generate corresponding respiration signal waveforms and display the respiration signal waveforms in real time;
the terminal controller synchronously displays the acquired electric stimulation sine wave and the respiratory signal waveform on the same coordinate axis interface, so that the synchronous degree of the current respiratory signal waveform and the electric stimulation sine wave is reflected, and respiratory feedback is carried out according to the synchronous degree, so that the respiratory signal waveform is within the allowable error of the electric stimulation sine wave.
2. A respiratory-synchronized transcutaneous electrical stimulation system according to claim 1, wherein for respiratory feedback, the degree of synchronization is displayed by color, wherein:
in the same coordinate axis interface, static color display is carried out on the electric stimulation sine wave, dynamic color display is carried out on the breathing signal waveform according to the synchronous calculation result, and the dynamic color is divided into a plurality of color areas, wherein the dynamic color is divided into a plurality of color areas;
if the respiration signal waveform in the preset time period and the electric stimulation sine wave in the time period are at a first synchronization degree, displaying the current respiration signal waveform as a first color area, and displaying a specific corresponding color in the first color area according to the height of the first synchronization degree, so as to perform first respiration feedback on a user;
if the respiration signal waveform in the preset time period and the electric stimulation sine wave in the time period are in the second synchronization degree, displaying the current respiration signal waveform as a second color area, and displaying a specific corresponding color in the second color area according to the height of the second synchronization degree, so as to perform second respiration feedback on the user;
if the respiration signal waveform in the preset time period and the electric stimulation sine wave in the time period are in the third synchronous degree, the current respiration signal waveform is displayed as a third color area, and the specific corresponding color in the third color area is displayed according to the height of the third synchronous degree, so that third respiration feedback is carried out on the user.
3. A respiratory-synchronized transcutaneous electrical stimulation system according to claim 2, wherein the degree of synchronization of the respiratory signal waveform with the electrical stimulation sine wave is obtained according to the formula:
Figure FDA0004109302590000021
wherein s is i Representing the corresponding value of the respiration signal waveform, f i Representing the value corresponding to the electro-stimulation sine wave.
4. A respiratory-synchronized transcutaneous electrical stimulation system as in claim 3, wherein the terminal controller comprises a third transceiver and a processor, a first input of the third transceiver in data communication with the first transceiver for obtaining the pulse signal, a second input of the third transceiver in data communication with the second transceiver for obtaining the respiration signal, and an output of the third transceiver for transmitting the pulse signal and the respiration signal to the processor, respectively, for obtaining the electrical stimulation sine wave and the respiration signal waveform, respectively.
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