CN116115898B

CN116115898B - Three-way liquid medicine transfer device with closed-loop operation

Info

Publication number: CN116115898B
Application number: CN202310056663.4A
Authority: CN
Inventors: 陈日志; 罗荣琼; 谢世庚; 陈伟权; 唐秉华; 郑梁宇; 杨丽臻
Original assignee: Zhanjiang Jianliyuan Medical Supplies Co ltd
Current assignee: Zhanjiang Jianliyuan Medical Supplies Co ltd
Priority date: 2023-01-18
Filing date: 2023-01-18
Publication date: 2023-12-15
Anticipated expiration: 2043-01-18
Also published as: CN116115898A

Abstract

The invention provides a three-way type liquid medicine transfer device and a liquid medicine transfer system which operate in a closed loop mode. The liquid medicine transfer device comprises two groups of dispensing needle assemblies, two groups of needle head sealing assemblies and a three-way reverser used for communicating the two groups of dispensing needle assemblies, can directly communicate two medicine containers to dispense medicines, realizes closed loop and quick operation of the medicines, effectively avoids leakage and volatilization problems of the medicines in preparation and transportation, and has the characteristics of simple structure, convenience in processing, low cost and high using convenience.

Description

Three-way liquid medicine transfer device with closed-loop operation

Technical Field

The invention belongs to the field of preparation and transfer devices of medicaments, and particularly relates to a three-way type liquid medicine transfer device and a liquid medicine transfer system with closed-loop operation.

Background

Volatilization and leakage of dangerous drugs such as chemotherapeutics in the process of preparation and transportation have great harm to the health of pharmacists and medical staff. Therefore, there is a strong need in the industry for a dispensing device that can achieve closed-loop operation during the drug formulation and transfer process, with low costs, simple structure, and convenient operation.

Disclosure of Invention

Aiming at the defects and practical application requirements of the prior art, the invention aims to provide a three-way type liquid medicine transfer device with closed-loop operation. This liquid medicine transfer ware can directly communicate two medicine containers and dispense, realizes the closed loop and the fast running of medicine, effectively avoids revealing and volatilizing problem of medicament in preparing the transportation, and liquid medicine transfer ware has simple structure, processing convenience, with low costs and the characteristics that use convenient degree is high simultaneously.

In order to achieve the above object, as a first aspect of the present invention, there is provided a three-way medical fluid transfer device for closed-loop operation, comprising: two groups of dispensing needle assemblies, two groups of needle head sealing assemblies and a three-way reverser for communicating the two groups of dispensing needle assemblies; the method is characterized in that:

the three-way commutator comprises a valve body and a valve core; wherein,

the valve body is internally provided with a first through hole and a second through hole which penetrate through two ends of the valve body in parallel, and the end surfaces of the two ends of the valve body are respectively provided with a first joint communicated with the first through hole and a second joint communicated with the second through hole, wherein the first joint and the second joint are parallel and independent; the middle section of the valve body is provided with a valve cavity with a single-side opening, the valve cavity is cylindrical, and the first through hole and the second through hole Kong Geduan are formed;

the valve core is of a columnar structure with the outer diameter matched with the inner diameter of the valve cavity and can be axially and rotatably embedded in the valve cavity; the valve core is internally provided with a first conduction cavity and a second conduction cavity which are independent from each other, the depth of the inner ends of the first conduction cavity and the second conduction cavity in the valve cavity corresponds to the first through hole and the second through hole respectively, and the outer ports are communicated with a first connecting hole and a second connecting hole which are fixedly arranged on the outer end surface of the valve core respectively;

Through the axial rotation of the valve core, the first conduction cavity can be selectively communicated with the first through hole on one side or the other side through the inner port of the first conduction cavity, and meanwhile, the second conduction cavity is communicated with the second through hole on the same side through the inner port of the second conduction cavity;

the dispensing needle assembly comprises a dispensing needle and a needle seat, and the dispensing needle is fixedly connected with the needle seat in a mode that the rear end of the dispensing needle is embedded into the front end of the needle seat; wherein,

the rear end of the needle seat is provided with a first connecting hole matched with a first joint of the end face of the valve body and a second connecting hole matched with a second joint of the end face of the valve body, and a first channel and a second channel which are respectively communicated with the first connecting hole and the second connecting hole and are independent of each other are arranged inside the needle seat;

the dispensing needle is of a double-layer columnar structure and is provided with an inner column channel and a side ring channel; the inner column channel is communicated with the first channel, and the side ring channel is communicated with the second channel;

the three-way reverser is fixedly and hermetically connected with the dispensing needle assembly by respectively embedding the first connector and the second connector on the end face of the valve body into the first connecting hole and the second connecting hole at the rear end of the needle seat;

the needle head sealing assembly comprises a sheath, a sealing piece and an elastic piece which are coaxially arranged with the dispensing needle; wherein,

The sheath is of a hollow cylindrical structure with front and rear openings and is sleeved at the front end of the needle seat in an axially movable manner;

the sealing piece is made of elastic materials and is fixedly arranged in the front end cylinder body of the sheath; a hole channel for a dispensing needle to pass through is arranged at the middle shaft of the sealing piece, and the inner diameter of the hole channel is smaller than the outer diameter of the dispensing needle;

the elastic piece is arranged between the sealing piece and the needle seat and supports the needle seat, and the elastic piece provides axial elastic support for the sealing piece at the front end;

under the non-pressure state, the elastic piece axially stretches, the sheath shields the dispensing needle inside the sheath, and under the elastic action of the elastic material, the front end part of the dispensing needle is tightly wrapped by the sealing piece, and the front end passage openings of the inner column passage and the side ring passage are sealed;

under the pressure state, the elastic piece is axially compressed, and the front end part of the dispensing needle comprising the front end passage openings of the inner column passage and the side ring passage can penetrate out of the sheath through the pore canal of the sealing piece.

In the present invention, unless otherwise indicated, in describing the structure of the dispensing needle assembly and the needle sealing assembly, the front end refers to one end in which the dispensing needle tip is directed, and the rear end refers to the opposite end. These are readily understood by those skilled in the art.

In the medical fluid transfer device of the present invention, the three-way diverter is a very critical steering communication control member. By axial rotation of the valve cartridge in the valve cavity, it is conveniently achieved that an external drive member, such as a dual chamber syringe, communicates with the first and second through holes on one side or the other of the valve cavity through the valve cartridge. Preferably, the three-way diverter is made of medical grade transparent material.

The function of the joint on the end face of the valve body is mainly expressed in two aspects: the three-way diverter is used as a plug-in type fixed connecting component between the three-way diverter and the dispensing needle component, and the three-way diverter is used as an inlet and an outlet of the liquid medicine or gas inlet and outlet valve body. In view of the fact that the valve body is not too large in size, it is preferable that the first joint and the second joint are arranged in as close proximity as possible. And optionally, a raised wing is provided on the end face of the valve body around the connector, forming a luer-like structure with the connector, the inside diameter of the wing matching the outside diameter of the rear end of the hub in the dispensing needle assembly.

As a preferred embodiment, the outer side walls of the first joint and the second joint on the end face of the valve body are conical surfaces, and at least one annular boss is arranged on the conical surfaces. Correspondingly, the shapes of the first connecting hole and the second connecting hole which are arranged at the rear end of the needle seat are respectively matched with the conical surfaces of the corresponding connectors, and the hole wall is provided with an annular groove corresponding to the annular boss. The three-way reverser and the dispensing needle component can be conveniently fixed and hermetically connected through the connection and the fixation of the connector and the connecting hole.

The middle section of the valve body is provided with a valve cavity with a single-side opening, and the valve cavity is cylindrical, and the first through hole and the second through hole Kong Geduan are formed. Preferably, the valve chamber is centrally arranged in the valve body perpendicular to the first and second through holes, and the axes of the first and second through holes and the valve chamber are located in the same plane. The arrangement can better ensure the accuracy of steering control and the synchronization of the alignment of the inner ports of the two conducting cavities and the two through holes.

The valve core is a columnar structure with the outer diameter matched with the inner diameter of the valve cavity and can be axially and rotatably embedded in the valve cavity. The middle section of the valve core is provided with a first neck groove along the radial direction, and the first neck groove is axially positioned between the inner port of the first conduction cavity and the inner port of the second conduction cavity; a second neck groove is arranged in the valve cavity at a corresponding position, and the second neck groove is positioned between the first through hole and the second through hole; and a sealing ring is arranged between the first neck groove and the second neck groove so as to ensure that the first through hole and the second through hole are separated in a closed mode on the premise that the valve core is rotatable, and gas-liquid circulation between the first through hole and the second through hole is avoided.

As described above, the valve element is axially rotatably embedded in the valve cavity. As one implementation mode of the invention, an annular groove which is coaxial and has a larger inner diameter is arranged at the opening of the valve cavity, a baffle matched with the annular groove is arranged on the valve core, and a sealing gasket is arranged between the annular groove and the baffle to ensure the tightness between the annular groove and the baffle. Further preferably, the valve body is provided with a hook at the outer edge of the annular groove, and the hook abuts against the baffle plate to fix the valve core on the valve body.

The first and second connection holes provided on the outer end surface of the valve body are used to connect with an external driving member such as a syringe. In one embodiment of the invention, the first and second connecting bores on the outer end face of the valve element are arranged adjacent and side by side. In another embodiment of the invention, the connection hole is configured as Lu Erkong.

The external driving component can be conveniently communicated with the first through hole and the second through hole on one side or the other side of the valve cavity through the valve core by the axial rotation of the valve core in the valve cavity. It is easy to understand that if the application needs, the purpose that the first conducting cavity is simultaneously communicated with the first through holes on two sides and the second conducting cavity is simultaneously communicated with the second through holes on two sides in a specific position can be realized by changing the structures of the inner ends of the first conducting cavity and the second conducting cavity in the valve core.

The liquid medicine transfer device comprises two groups of dispensing needle assemblies communicated with the three-way reverser, wherein the two groups of dispensing needle assemblies have the same structure and the same specification (size) or different specifications. For specific structure, see applicant's prior application number 202211220305.4, which is incorporated herein in its entirety.

The dispensing needle assembly comprises a dispensing needle and a needle seat, and the dispensing needle is fixedly connected with the needle seat in a mode that the rear end of the dispensing needle is embedded into the front end of the needle seat.

The dispensing needle is of a double-layer columnar structure and is provided with an inner column channel and a side ring channel. As a preferred embodiment, the dispensing needle can be composed of an inner needle tube and an outer needle tube, the inner needle tube is arranged inside the outer needle tube in a penetrating way, two ends of the inner needle tube extend out of the outer needle tube, at the moment, an inner column channel is composed of an inner cavity of the inner needle tube, and a side ring channel is composed of a cavity between the outer needle tube and the inner needle tube.

The inner needle tube and the outer needle tube can be mutually independent, can be integrally formed and are fixedly connected with each other, and when the inner needle tube and the outer needle tube are of the latter type, the front end of the outer needle tube is preferably in closed fixed connection with the side wall of the front end of the inner needle tube. Further preferably, the front end of the inner needle tube is provided with an inclined opening, or the front end of the inner needle tube is provided with a tip and a side opening; the front side wall of the outer needle tube is provided with a side opening. The design opening is not only favorable to the medicine container of medicine needle penetration of dispensing, can reduce the interference between the interior post passageway and the side ring passageway in addition, simultaneously, if regard as the liquid medicine passageway with the side ring passageway, the side opening that sets up behind more laminating medical personnel inverts the operating habit of liquid medicine bottle when preparing the medicament, is favorable to sucking liquid medicine (especially the liquid medicine of bottleneck department) more fully, avoids the medicament extravagant or promotes the operation risk because of the secondary operation.

The needle stand is a carrier provided with a dispensing needle and a needle head sealing assembly. As described above, the rear end of the needle seat is provided with the first connecting hole matched with the first joint on the end face of the valve body and the second connecting hole matched with the second joint, and the interior of the needle seat is provided with the first channel and the second channel which are respectively communicated with the first connecting hole and the second connecting hole and are independent from each other; the inner column channel of the dispensing needle is communicated with the first channel, and the side ring channel is communicated with the second channel.

As a preferred embodiment, the front end part of the needle seat is provided with a mounting groove, and a needle penetrating table (which is equivalent to digging out a block from the front end part of the needle seat) with the appearance structure matched with the mounting groove is arranged in the mounting groove; the front end openings of the first channel and the second channel are positioned at the bottom of the mounting groove, and the front end opening of the first channel is coaxial with the dispensing needle; the needle penetrating table is internally provided with a front-back penetrating duct at the position corresponding to the shaft of the dispensing needle and is composed of a needle penetrating hole at the front part and a fixing hole at the rear part, wherein the needle penetrating hole is horn-shaped, the inner diameter of the needle penetrating hole gradually decreases from front to back until reaching the fixing hole, and the inner diameter of the fixing hole is matched with the outer diameter of the outer needle tube; the back end surface of the needle threading platform is provided with a communication groove, and two ends of the communication groove are respectively communicated with the second channel and the fixing hole. The rear end of the inner needle tube of the dispensing needle passes through the needle penetrating table and is fixed in the first channel in an embedded manner; the rear end of the outer needle tube is fixed in the fixing hole of the needle threading table in an embedded mode.

Further preferably, in the above embodiment, the first channel in the needle holder is disposed coaxially with the dispensing needle, and the second channel is disposed in parallel to one side of the first channel.

It is further preferred that the cross-section of the needle-threading table is non-circular and remains axially unchanged. The purpose of this design makes the needle threading platform only can install the mounting groove of needle file with fixed angle in, makes things convenient for the accurate butt joint of needle threading platform bottom intercommunication groove and second passageway.

After a sufficient understanding of the construction of the needle hub and the dispensing needle, it will be readily ascertainable to those skilled in the art how to assemble and form the dispensing needle assembly. For example, when the dispensing needle is composed of an inner needle tube and an outer needle tube which are independent of each other, the needle threading platform can be taken out first, the rear end of the inner needle tube is embedded into the first channel, then the outer needle tube is fixed on the needle threading platform, and then the outer needle tube and the needle threading platform which are integrated are sleeved outside the inner needle tube and inserted into the mounting groove; or when the inner needle tube and the outer needle tube are integrally formed and fixedly connected with each other, the needle threading platform can be taken out first, the dispensing needle is fixed on the needle threading platform, the rear end of the outer needle tube is ensured to be embedded into the fixing hole of the needle threading platform, the rear end of the inner needle tube penetrates out of the needle threading platform, and then the needle threading platform is inserted into the mounting groove, and the rear end of the exposed inner needle tube is ensured to be completely embedded into the first channel.

In the invention, the two groups of needle head sealing assemblies have the same structure and the same specification (size) or different specifications, and are respectively connected with the two groups of dispensing needle assemblies in an adaptive manner. The needle head sealing assembly is arranged, so that the function of preventing puncture can be exerted, the whole medicine liquid preparation and transferring process can be ensured to be in a fully-sealed state, and the risk of leakage of the medicine liquid from the front end passage opening is avoided. Assemblies having similar structures and functions have been reported in applicant's prior patents, such as CN111346008A and CN111346009a, but their manufacturing processes are relatively complex, and require the use of relatively complex structural components rather than the assembly of simple structural components, so that specific equipment is required for mass production or high requirements for equipment accuracy are required.

In order to achieve the purposes of simplifying the manufacturing process, facilitating assembly and further reducing mass production cost, the applicant optimizes the structure of the needle head sealing assembly. For specific structure see also applicant's prior application number 202211220305.4, which is incorporated herein in its entirety. As a preferred embodiment of the present invention, the needle seal assembly comprises a coaxially disposed sheath, a closure member, an elastic member and an inner sleeve, wherein:

The front end part of the sheath takes smaller radial dimension to form a composite cylindrical structure consisting of a first cylindrical section with smaller inner diameter and a second cylindrical section with larger inner diameter;

the sealing piece is designed to be of an inverted T-shaped structure in cross section, the front diameter corresponds to the inner diameter of the first barrel section, the rear diameter corresponds to the inner diameter of the second barrel section, and therefore the sealing piece can fill at least part of the inner cavity of the second barrel section while completely filling the inner cavity of the first barrel section;

the inner diameter of the inner sleeve corresponds to the outer diameter of the needle seat, the outer diameter of the inner sleeve corresponds to the inner diameter of the second barrel section of the sheath, the front end face of the inner sleeve is closed, and a through hole for the medicine dispensing needle to pass through is arranged in the center of the end face; the inner sleeve is fixedly connected in the second barrel section of the sheath, and the front end face of the inner sleeve is abutted against the rear end face of the sealing piece;

the elastic piece is arranged in the inner sleeve, and two ends of the elastic piece are respectively abutted against the inner surface of the front end of the inner sleeve and the front end face of the needle seat.

Through improving the structure of sheath and airtight piece and add the inner skleeve, airtight piece is spacing fixed, and both ends all butt hard material around the elastic component, and overall structure and performance are more stable. Further preferably, the outer wall of the inner sleeve is provided with a buckle, the second barrel section of the sheath is provided with a corresponding clamping hole, and the fixed connection between the sheath and the inner sleeve is realized through the cooperation of the buckle and the clamping hole when the inner sleeve is inserted into the sheath. Preferably, the rear end opening of the inner sleeve is provided with an annular boss in a radially outward manner, and when the front end surface of the inner sleeve abuts against the rear end surface of the sealing member, the annular boss at the rear end is exposed out of the sheath and abuts against the rear end of the sheath.

It will be readily appreciated that during use of the medical fluid transfer device of the present invention, the needle seal assembly remains attached to the hub throughout the axial movement of the needle seal assembly as the elastic member expands and contracts. As a preferred embodiment, both the front end inner surface of the inner sleeve and the front end surface of the needle holder are provided with snap-fit structures, whereby a fixed connection with the elastic member is achieved. As a further preferred embodiment, the side face of the needle holder is provided with an L-shaped groove consisting of an axial groove and a transverse groove (perpendicular to the axial groove), the rear end of the inner sleeve is provided radially inwards with a sliding table which is embedded in the L-shaped groove and can slide along the groove. Through the position design of slip table and L shape recess, can nimble adjustment and restriction syringe needle seal assembly for the range of motion of needle file. Along with the sliding table sliding backwards along the axial groove, the elastic piece is compressed, the dispensing needle penetrates out of the sealing piece, and after the setting degree is reached, the sliding table rotates along the transverse groove, so that the axial movement of the needle head sealing assembly can be limited, and the limiting and fixing effects are achieved.

The closure is made of an elastic material, preferably any one of rubber, silicone, synthetic rubber. Suitable elastic materials should meet the relevant criteria for medical materials, as will be readily appreciated and ascertained by those skilled in the art. In a preferred embodiment, the front end surface of the sealing member protrudes beyond the front end surface of the sheath, so that the sealing member made of an elastic material can be attached to the adhesive port of the medicine container during preparation and transfer of the medicine liquid, and the sealing member can better seal the opening of the medicine container.

The elastic member may be an elastically folded tube, a spring, or the like, preferably a spring.

When the liquid medicine transfer device is matched with the liquid medicine connector to carry out liquid medicine preparation and transfer operation, preferably, the outer wall of the front end of the sheath is symmetrically provided with two buckling tables protruding outwards in the radial direction so as to be fixedly connected with the liquid medicine connector.

According to the liquid medicine transfer device, under the non-pressurized state, the elastic piece axially stretches, the sheath shields the dispensing needle inside the sheath, and under the elastic action of the elastic material, the front end part of the dispensing needle is tightly wrapped by the sealing piece, and the front end passage openings of the inner column passage and the side ring passage are sealed; under the pressure state, the elastic piece is axially compressed, and the front end part of the dispensing needle comprising the front end passage openings of the inner column passage and the side ring passage can penetrate out of the sheath through the pore canal of the sealing piece. The initial state of the medical fluid transfer device may be a non-pressurized state or a pressurized state, but for the purposes of preventing puncture, preventing contamination, and preventing inertial deformation of the elastic member and the sealing member, the initial state is preferably a non-pressurized state.

Preferably, the medical fluid transferor of the present invention further comprises a protective cap. In the standby state, the protective cap is sleeved on the sheath so as to avoid potential pollution risks.

The medical fluid transfer device of the present invention may further include an external driving member connected to the first and second connection holes provided on the outer end surface of the valve body. As a preferred embodiment, the external driving member includes a first syringe and a second syringe respectively communicating with the first connection hole and the second connection hole on the outer end surface of the spool.

Further preferably, the external driving member is a dual-chamber syringe, and is composed of a first syringe, a first piston rod capable of sliding back and forth along an inner cavity in the first syringe, a second syringe and a second piston rod capable of sliding back and forth along the inner cavity in the second syringe, wherein the first syringe and the second syringe are fixedly arranged side by side, in the same direction and with the front ends flush; the front end face of the first injection cylinder is provided with a first joint, and the front end face of the second injection cylinder is provided with a second joint; the valve core and the double-chamber injector are fixedly and hermetically connected through the first connecting hole and the second connecting hole which are respectively embedded in the outer end face of the valve core by the first connector and the second connector. In the dual chamber syringe, the specifications of the first syringe and the second syringe are not particularly limited, and may be the same or different, but in view of convenience in production and practical operation, the first syringe and the second syringe have the same size specifications as preferred embodiments. Preferably, the first syringe and the second syringe are made of transparent materials, and the surface of the cylinder is provided with scales for displaying the volume.

Similar to the fittings on the end face of the valve body, the function of the fittings on the front end face of the syringe is also mainly manifested in two aspects: the valve is used as a fixed connecting component for connecting the injector and the valve core, and is used as an inlet and an outlet for liquid medicine or gas to enter and exit the injection cylinder. In view of the size constraints of the needle mount, it is preferable that the first and second connectors are disposed in as close proximity as possible.

As a preferred embodiment, the outer side walls of the first joint and the second joint are conical surfaces, and at least one annular boss is arranged on the conical surfaces. Correspondingly, the shapes of the first connecting hole and the second connecting hole on the outer end face of the valve core are respectively matched with the conical surfaces of the corresponding connectors, and the hole wall is provided with an annular groove corresponding to the annular boss. The valve core and the double-chamber injector can be conveniently fixed and hermetically connected through the connection and the insertion fixation of the connector and the connecting hole. Further, if the first and second connection holes on the spool outer end face are configured as Lu Erkong, the first and second fittings on the dual chamber syringe are provided as structurally matched first and second luer fittings, respectively.

As a second aspect of the present invention, there is also provided a medical fluid transfer system comprising:

The three-way liquid medicine transfer device with the closed-loop operation and a liquid medicine connector for fixedly connecting the liquid medicine transfer device to a medicine container;

one end of the pipetting connector is used for detachably and fixedly connecting with a medicine container, and the other end is used for detachably and fixedly connecting with a liquid medicine transfer device; when in fixed connection, the front end surface of the sealing piece is abutted against the container mouth of the medicine container.

As a preferred embodiment, the pipetting connector comprises a first sleeve and a second sleeve which are coaxial and connected with each other, the first sleeve is used for being detachably sleeved at the front end of the sheath of the liquid medicine transfer device, the second sleeve is used for being detachably sleeved at the container mouth of the medicine container, and the front end face of the sealing piece and the container mouth of the medicine container keep stable abutting connection in the sleeve when the pipetting connector is fixedly connected.

Further preferably, the outer edge of the second sleeve is symmetrically provided with axially forwardly extending snap fingers, and the rear end of each snap finger is provided with a rearwardly extending release arm, by means of which the second sleeve is secured to the container mouth and detached from the container mouth by means of the release arms.

Further preferably, the inner wall of the first sleeve is symmetrically provided with two buckling grooves, the buckling grooves are of an L-shaped structure formed by an axial groove and a transverse groove, and correspondingly, the outer wall of the front end of the sheath is symmetrically provided with two buckling tables protruding outwards in the radial direction. When the sheath is inserted into the first sleeve, the buckling table synchronously enters the axial groove of the buckling groove, and after the buckling table reaches a preset position, the sheath is rotated to enable the buckling table to rotate into the transverse groove, so that the liquid medicine transfer device can be fixed with the liquid transferring connector; and the disassembly and separation can be performed by reverse operation.

In the three-way type liquid medicine transfer device with closed-loop operation, after a three-way reverser, a dispensing needle assembly, a needle head sealing assembly and an external driving component (a double-chamber injector) are fixed and connected in a closed mode, when a valve core rotates to enable inner ports of a first conducting cavity and a second conducting cavity to be respectively communicated with a first through hole and a second through hole on one side, an inner column channel, a first channel and a first connecting hole of the dispensing needle assembly are sequentially communicated with the first through hole and the first conducting cavity of the three-way reverser from front to back, and then are communicated with a first injection cylinder through a first connecting hole on the outer end face of the valve core to form a closed passage I; the side ring channel, the second channel and the second connecting hole of the dispensing needle assembly are sequentially communicated with the second through hole and the second conduction cavity of the three-way reverser from front to back, and then are communicated with the second injection cylinder through the second connecting hole on the outer end face of the valve core, so that a closed passage II is formed. The two closed passages I and II are mutually independent, and one of the two passages is used for conveying the liquid medicine in the preparation and transfer processes of the liquid medicine, and the other passage can play roles in conveying gas and balancing air pressure.

The liquid medicine transfer device has the characteristic of double-chamber circulation, wherein the closed passages I and II are mutually independent, the closed passage I is communicated with the first injection cylinder and the medicine container, and the closed passage II is communicated with the second injection cylinder and the medicine container. After the front end part of the dispensing needle is penetrated into the medicine container, one of the first injection cylinder and the second injection cylinder is used for transferring medicine liquid, and the other one of the first injection cylinder and the second injection cylinder can move back and forth through the piston rod and is matched with air sucked in the injection cylinder in advance, so that the aim of balancing air pressure is fulfilled.

The liquid medicine transfer device can be used for the purposes of preparing mixed medicines, transferring the prepared liquid medicine into an infusion bottle or an indwelling needle and the like. With a full understanding of the construction of the above-described medical fluid transfer device and transfer system of the present invention, it will be readily apparent to those skilled in the art how to use it for medical fluid preparation and transfer.

Taking the example of preparing a drug solution (involving dissolving a drug powder) and pouring back into an infusion bottle, the flow of using the drug solution transfer system of the present invention will be briefly described. In the used medicine liquid transfer device, two groups of medicine dispensing needle assemblies and needle head sealing assemblies are symmetrically arranged by taking a three-way commutator as a center, and the prescription positions are respectively marked as side A and side B of the three-way commutator for simplifying the description. The use flow may include the following steps:

(1) The first piston rod of the dual chamber syringe is pulled back until the volume of the front cavity of the first syringe barrel is greater than the volume of the liquid medicine to be prepared. In order to perform the gas storage link, the double-chamber injector can be separated from the valve core in advance, and is fixedly connected with the valve core again after gas storage.

(2) Sleeving a second sleeve of the liquid transferring connector A on a bottle opening of an infusion bottle (with an inverted bottle opening facing downwards), fixing the second sleeve with the bottle opening by using a clamping claw, and then holding a sheath (provided with a buckling table) at the side of the liquid medicine transferring device A to align and insert the first sleeve (provided with a buckling groove) of the liquid transferring connector A, and rotating and fixing the first sleeve; at this time, the front end face of the sealing member is abutted with the rubber port of the infusion bottle in the sleeve.

(3) The valve body of the liquid medicine transfer device is held to push upwards, and along with the compression of the side A spring, the side A dispensing needle pierces the sealing piece and pierces the infusion bottle. After the needle is completely penetrated, the sheath is rotated, so that the needle head sealing component and the needle seat are limited and fixed.

(4) Sleeving a second sleeve of the pipetting connector B on the bottle mouth of the penicillin bottle, fixing the second sleeve with the penicillin bottle by using a clamping claw, and then holding a sheath (provided with a buckling table) at the side of the liquid medicine transfer device B to align with a first sleeve (provided with a buckling groove) inserted into the pipetting connector B and rotationally fixing the first sleeve; at this time, the front end face of the sealing piece is abutted with the rubber port of the penicillin bottle in the sleeve.

(5) The valve body of the liquid medicine transfer device is held and fixed, the penicillin bottle is pushed upwards, and the B side dispensing needle pierces the sealing piece and pierces the penicillin bottle along with the compression of the B side spring. After the needle is completely penetrated, the sheath is rotated, so that the needle head sealing component and the needle seat are limited and fixed.

Through the steps (2) to (5), the connection state of the infusion bottle at the upper part, the liquid medicine transfer device at the middle part and the penicillin bottle at the lower part is formed.

(6) The valve core is rotated towards the side A, so that the inner ends of the first conducting cavity and the second conducting cavity are respectively communicated with the first through hole and the second through hole on the side A. Then, the second piston rod of the double-chamber injector is pulled, and part of liquid medicine (such as physiological saline) in the infusion bottle is extracted into the second injection cylinder through the closed passage II; at this time, negative pressure is generated in the infusion bottle, the first piston rod moves forwards (can be assisted by manual operation) under the action of internal and external pressure difference, and air reserved in the first injection cylinder is supplemented into the infusion bottle until internal and external air pressure is balanced.

(7) After the liquid medicine is extracted, the valve core is rotated towards the side B, so that the inner ends of the first conduction cavity and the second conduction cavity are respectively communicated with the first through hole and the second through hole on the side B. Then, pushing a second piston rod of the double-chamber syringe, and injecting the liquid medicine into the penicillin bottle from the second injection cylinder through the closed passage II; at this time, positive pressure is generated in the penicillin bottle, and air in the penicillin bottle automatically enters the first injection cylinder through the closed passage I and pushes the first piston rod to move backwards.

(8) After the original medicinal powder in the penicillin bottle is fully dissolved by the medicinal liquid injected into the penicillin bottle, pulling a second piston rod to extract the mixed medicinal liquid in the penicillin bottle into a second injection cylinder through a closed passage II; at this time, negative pressure is generated in the infusion bottle, gas in the first injection cylinder is automatically supplemented into the penicillin bottle, and the first piston rod moves forwards (can be manually assisted) under the action of internal and external pressure difference until internal and external air pressure is balanced.

(9) After the liquid medicine is extracted, the valve core rotates towards the side A again, so that the inner ends of the first conduction cavity and the second conduction cavity are respectively communicated with the first through hole and the second through hole on the side A. Then, pushing a second piston rod of the double-chamber syringe, and injecting the mixed liquid medicine into the infusion bottle from the second injection cylinder through the closed passage II; at this time, positive pressure is generated in the infusion bottle, and air in the infusion bottle automatically enters the first injection cylinder through the closed passage I and pushes the first piston rod to move backwards.

(10) After the mixed liquid medicine is completely injected into the infusion bottle, the limit fixation of the needle head sealing assemblies and the needle seat at the two sides is released, the dispensing needle is reset under the assistance of the elastic potential energy of the spring, namely, the dispensing needle is withdrawn from the infusion bottle and the penicillin bottle and is sealed by the sealing piece again, and then the fixed connection between the liquid medicine transfer device and the liquid transferring connector is released and pulled out of the liquid transferring connector.

In the preparation and transfer process, the second injection cylinder transmits the liquid medicine through the closed passage II, and the first injection cylinder moves back and forth through the first piston rod to balance the internal and external air pressure of the transfer system by matching with the air sucked in the first injection cylinder in advance. The back-and-forth movement of the first piston rod can be completed only by the action of internal and external pressure differences under the condition of not being interfered by external force, and the process can be flexibly adjusted by manpower.

Compared with the prior art, the invention has the beneficial effects that at least the following aspects are included:

(1) The liquid medicine transfer device has exquisite structural design, and all parts are components which are convenient for mass production and assembly, and the liquid medicine transfer device does not need to use relatively complex structural components and special equipment. And the product has stable structure and performance, low cost and high yield.

(2) By controlling the rotation of the valve core, it is convenient to control which side an external drive member (e.g., a dual chamber syringe) communicates with. The whole preparation and transfer process only needs to be installed and fixed once, repeated plugging and unplugging operations are not needed, and the operation portability is obviously improved.

(3) In the process of preparing and transferring the medicine, the internal and external air pressures of the medicine liquid transferring system are completely balanced. And can realize totally enclosed medicine preparation and transfer, realize the maximize and reduce the medicine and reveal the risk, airtight effect is very excellent.

The invention is further described below with reference to the accompanying drawings.

Drawings

FIG. 1 is a schematic cross-sectional view of the medical fluid transfer device of example 1 in a non-pressurized state, wherein the valve element is not in communication with either side;

FIG. 2 is a schematic view showing a perspective partial sectional structure of the drug solution shifter of example 1 in a non-pressurized state;

FIG. 3 is a schematic view showing a perspective partial sectional structure of the medical fluid transfer apparatus of example 1 in a pressurized state;

FIG. 4 is a representative physical diagram of the drug solution shifter;

FIG. 5 is a schematic cross-sectional view of a pipetting connector in example 2;

FIG. 6 is a schematic sectional view showing the operation of the drug solution transfer system of example 2.

Reference numerals: 1. a three-way commutator; 11. a valve body; 111. a first through hole; 112. a second through hole; 113. a first joint; 114. a second joint; 115. wings; 12. a valve core; 121. a first conduction cavity; 122. a second conduction cavity; 123. a first neck groove; 124. a seal ring; 125. an annular groove; 126. a baffle; 127. a sealing gasket; 128. a hook; 129. a first connection hole (spool); 120. a second connection hole (spool); 2. a dispensing needle assembly; 21. a dispensing needle; 211. an inner column passage; 212. a side ring channel; 22. a needle stand; 221. a first connection hole (needle mount); 222. a second connection hole (needle mount); 223. a first channel; 224. a second channel; 23. a needle threading table; 231. a communication groove; 3. a needle seal assembly; 31. a sheath; 32. a sealing member; 33. an elastic member; 34. an inner sleeve; 4. a dual chamber syringe; 41. a first syringe; 42. a first piston rod; 43. a second syringe; 44. a second piston rod; 45. a first joint; 46. a second joint; 5. a pipetting connector; 51. a first sleeve; 52. a second sleeve; 53. a clamping claw; 54. a release arm; 55. and the groove is buckled.

Detailed Description

For a better illustration of the objects, technical solutions and advantages of the present invention, the following detailed description of the present invention will be given with reference to the accompanying drawings and examples. The following examples are illustrative of the invention and are not intended to limit the scope of the invention.

Example 1

As shown in fig. 1, a three-way medical fluid transfer device for closed-loop operation, comprising: three-way reverser 1, two sets of dispensing needle assemblies 2, two sets of needle seal assemblies 3 and dual chamber syringe 4.

The three-way commutator 1 is made of medical transparent plastic and comprises a valve body 11 and a valve core 12.

A first through hole 111 and a second through hole 112 penetrating both ends of the valve body 11 are provided in parallel in the valve body 11, and a first joint 113 communicating with the first through hole 111 and a second joint 114 communicating with the second through hole 112 are provided on end surfaces of both ends of the valve body 11, the first joint 113 and the second joint 114 being provided independently of each other in parallel and adjacent to each other. A raised wing 115 is provided on the end face of the valve body 11 around the fitting, and together with the fitting forms a luer-like structure, the inner diameter of the wing 115 matching the outer diameter of the rear end of the hub 22 in the dispensing needle assembly 2.

The middle section of the valve body 11 is provided with a valve cavity with a single-side opening in the valve body 11 in a mode of being perpendicular to the first through hole 111 and the second through hole 112, the valve cavity is cylindrical, the first through hole 111 and the second through hole 112 are separated, and the axes of the first through hole 111, the second through hole 112 and the valve cavity are located on the same plane.

The valve core 12 is a columnar structure with an outer diameter matched with the inner diameter of the valve cavity, and is axially and rotatably embedded in the valve cavity. The valve core 12 is provided with a first conducting cavity 121 and a second conducting cavity 122 which are independent from each other (only the inner ports of the two conducting cavities are exposed in fig. 1 due to the angle problem, more structures can be seen in fig. 6), the depth of the inner ports of the first conducting cavity 121 and the second conducting cavity 122 in the valve cavity corresponds to the first through hole 111 and the second through hole 112 respectively, and the outer ports are respectively communicated with a first connecting hole 129 and a second connecting hole 120 which are fixedly arranged on the outer end face of the valve core 12 in an adjacent and side-by-side mode. The valve core 12 is provided with a first neck groove 123 in a middle section position in a radial direction, and the first neck groove 123 is axially located between an inner port of the first conduction chamber 121 and an inner port of the second conduction chamber 122. The interior of the valve chamber is provided with a second neck groove (not shown in the figures) at a corresponding position, said second neck groove being located between the first through hole 111 and the second through hole 112. A sealing ring 124 is disposed between the first neck groove 123 and the second neck groove, so as to ensure that the first through hole 111 and the second through hole 112 are separated in a closed manner on the premise that the valve core 12 is rotatable, and avoid gas-liquid communication between the two.

An annular groove 125 with the same shaft and larger inner diameter is arranged at the opening of the valve cavity, a baffle 126 matched with the annular groove 125 in structure is arranged on the valve core 12, and a sealing gasket 127 is arranged between the annular groove 125 and the baffle 126 to ensure the tightness between the annular groove and the baffle 126. The valve body 11 is provided with a hook 128 at the outer edge of the annular groove 125, and the hook 128 abuts against the baffle 126 to fix the valve core 12 on the valve body 11.

By axial rotation of the valve spool 12 in the valve chamber, the first through-hole 111 on one side or the other side can be selectively communicated with the first through-hole 121 via the inner port thereof, while the second through-hole 122 communicates with the second through-hole 112 on the same side via the inner port thereof.

The two groups of dispensing needle assemblies 2 have the same structure and specification and are communicated with the three-way reverser 1 in a symmetrical mode. The dispensing needle assembly 2 comprises a dispensing needle 21 and a needle hub 22.

The dispensing needle 21 has a double-layer columnar structure and is composed of an inner needle tube and an outer needle tube which are fixed with each other. The inner needle tube is longer than the outer needle tube, the two ends of the inner needle tube extend out of the outer needle tube, and the front end of the outer needle tube is fixedly connected with the side wall of the front end of the inner needle tube in a closed mode. The front end of the inner needle tube is an inclined opening, and the front end of the outer needle tube is provided with a side opening. Thus, the inner cavity of the inner needle tube forms an inner column passage 211, and the side ring passage 212 is formed by a cavity between the outer needle tube and the inner needle tube.

The rear end of the needle holder 22 is provided with a first connection hole 221 matching the position and shape of the first joint 113 on the end face of the valve body 11 and a second connection hole 222 matching the position and shape of the second joint 114, and the inside of the needle holder 22 is provided with a first passage 223 and a second passage 224 communicating with the first connection hole 221 and the second connection hole 222, respectively, and independent from each other, wherein the first passage 223 is coaxially disposed with the dispensing needle 21, and the second passage 224 is disposed in parallel to one side of the first passage 223.

The front end portion of the needle holder 22 is provided with a mounting groove having an elliptical cross section, and the front ports of the first passage 223 and the second passage 224 are both located at the bottom of the mounting groove. The needle penetrating table 23 with the appearance structure matched with the mounting groove is arranged in the mounting groove, a front-back penetrating pore canal is arranged in the needle penetrating table 23 at the position corresponding to the axis of the dispensing needle 21, the needle penetrating table consists of a needle penetrating hole at the front part and a fixing hole at the rear part, the needle penetrating hole is horn-shaped (the mounting of the dispensing needle 21 is facilitated), the inner diameter gradually decreases from front to back until reaching the fixing hole, and the inner diameter of the fixing hole is matched with the outer diameter of the outer needle tube. The rear end surface of the needle threading platform 23 is also provided with a communication groove 231, and two ends of the communication groove are respectively communicated with the second channel 224 and the fixing hole.

The dispensing needle 21 is fixedly connected to the needle holder 22 in such a manner that its rear end is embedded in the needle holder 22. At this time, the rear end of the inner needle tube passes through the hole of the needle threading table 23 and is fixed in the first channel 223 in an embedded manner; the rear end of the outer needle tube passes through the needle penetrating hole and is fixed in the fixing hole of the needle penetrating table 23 in an embedded mode.

The outer side walls of the first joint 113 and the second joint 114 on the end face of the valve body 11 are tapered surfaces, and an annular boss (not shown) is provided on the tapered surfaces. Accordingly, the first connection hole 221 and the second connection hole 222 provided at the rear end of the needle holder 22 are respectively shaped to match the tapered surfaces of their corresponding connectors, and an annular groove (not shown) corresponding to the annular boss is provided on the hole wall. The three-way reverser 1 is fixedly and hermetically connected with the dispensing needle assembly 2 by respectively embedding the first joint 113 and the second joint 114 of the end surface of the valve body 11 into the first connecting hole 221 and the second connecting hole 222 of the rear end of the needle seat 22.

The needle seal assembly 3 comprises a coaxially arranged sheath 31, a closure member 32, an elastic member 33 and an inner sleeve 34.

The front end portion of the sheath 31 is formed in a composite tubular structure having a first tubular segment with a smaller inner diameter and a second tubular segment with a larger inner diameter. Two buckling tables protruding outwards in the radial direction are symmetrically arranged on the outer wall of the first barrel section and are used for being fixedly connected with the pipetting connector; the second barrel section is symmetrically provided with two clamping holes on the barrel wall adjacent to the rear port.

The closure 32 is made of silicone and has an inverted T-shaped cross-section with a front diameter equal to the inner diameter of the first barrel section of the sheath 31 and a length slightly greater than the axial length of the first barrel section and a rear diameter equal to the inner diameter of the second barrel section. The sealing member 32 completely fills the first barrel section inner cavity and the second barrel section front end inner cavity, and the front end surface protrudes beyond the front end surface of the sheath 31. The central axis of the sealing member 32 is provided with a hole through which the dispensing needle 21 passes, and the inner diameter of the hole is smaller than the outer diameter of the dispensing needle 21.

The inner diameter and the outer diameter of the inner sleeve 34 correspond to the outer diameter of the needle seat 22 and the inner diameter of the second barrel section of the sheath 31 respectively, the front end face of the inner sleeve is closed, a through hole for the medicine dispensing needle 21 to pass through is arranged in the center of the end face, the rear port is provided with an annular boss in a radially outward manner, and two buckles matched with the clamping holes are symmetrically arranged on the outer wall adjacent to the rear port.

The inner sleeve 34 is inserted into the second barrel section of the sheath 31, and the fixed connection between the inner sleeve 34 and the second barrel section is realized through the matching of the buckle and the clamping hole, meanwhile, the front end surface of the inner sleeve 34 is abutted against the rear end surface of the sealing piece 32, and the annular boss at the rear end is exposed out of the sheath 31 and is abutted against the rear end of the sheath 31.

The elastic member 33 is a spring, and is disposed in the inner sleeve 34, and both ends thereof are respectively abutted against the inner surface of the front end of the inner sleeve 34 and the front end surface of the needle holder 22.

The side face of the needle seat 22 is symmetrically provided with two L-shaped grooves consisting of an axial groove and a transverse groove, and correspondingly, the rear end of the inner sleeve 34 is symmetrically provided with two sliding tables radially inwards, and the sliding tables are embedded in the L-shaped grooves and can slide along the grooves.

As shown in fig. 1, the needle sealing assembly 3 is in a non-pressurized state, the elastic member is axially stretched, the sliding table of the inner sleeve 34 is positioned at the front end of the axial groove on the side surface of the needle seat 22, the sheath 31 shields the dispensing needle 21 inside the sheath 31, and under the elastic force of silica gel, the sealing member 32 tightly wraps the front end part of the dispensing needle 21, and the front end passage openings of the inner column passage 211 and the side ring passage 212 are sealed inside.

The dual chamber syringe 4 is composed of a first syringe 41, a first piston rod 42 slidable back and forth along the inner cavity in the first syringe 41, a second syringe 43, and a second piston rod 44 slidable back and forth along the inner cavity in the second syringe 43. The first syringe 41 and the second syringe 43 are made of transparent materials, have the same specification, are fixedly arranged side by side in the same direction and have the front ends flush, and the surface of the cylinder is provided with scales (not shown in the figure) for displaying the volumes. The front end surfaces of the first syringe 41 and the second syringe 43 are respectively provided with a first joint 45 and a second joint 46 adjacent to each other, the two joints are identical in structure, the outer side walls are tapered surfaces, and an annular boss (not shown) is provided on the tapered surfaces.

The first connecting hole 129 and the second connecting hole 120 on the outer end surface of the valve core 12 are respectively matched with the conical surfaces of the corresponding connectors, and annular grooves (not shown in the figure) corresponding to the annular bosses are arranged on the hole walls. The valve cartridge 12 is fixedly and hermetically connected to the dual chamber syringe 4 by fitting the first and second connectors 45 and 46 of the dual chamber syringe 4 into the first and second connection holes 129 and 120, respectively, on the outer end surface of the valve cartridge 12.

In the three-way type drug solution transfer device of fig. 1, the valve core 12 is in a position not communicating with either side through-hole in the valve body 11. When the valve core 12 rotates to enable the inner ends of the first conduction cavity 121 and the second conduction cavity 122 to be respectively communicated with the first through hole 111 and the second through hole 112 on one side, the inner column channel 211, the first channel 223 and the first connecting hole 221 of the dispensing needle assembly 2 are sequentially communicated with the first through hole 111 and the first conduction cavity 121 of the three-way reverser 1 from front to back, and then are communicated with the first injection cylinder 41 through the first connecting hole 129 on the outer end surface of the valve core 12 to form a closed passage I; the side ring channel 212, the second channel 224 and the second connecting hole 222 of the dispensing needle assembly 2 are sequentially communicated with the second through hole 112 and the second conducting cavity 122 of the three-way reverser 1 from front to back, and then are communicated with the second injection cylinder 43 through the second connecting hole 120 on the outer end surface of the valve core 12, so as to form a closed passage II. The closed passages I and II are independent from each other.

Fig. 2 and 3 are schematic views showing a perspective partial sectional structure of the above-mentioned medical fluid transfer device in a non-pressurized and pressurized state of the needle sealing assembly. In the compressed state, the spring 33 is compressed axially, and the front end portion of the dispensing needle 21 including the front end passage openings of the inner column passage 211 and the side ring passage 212 passes through the sheath 31 via the passage of the seal 32. The sliding table of the inner sleeve 34 slides backwards synchronously along the axial groove and moves into the transverse groove through the rotary sheath 31, so that the axial movement of the needle sealing assembly 3 is limited, and the effect of limiting and fixing is achieved.

FIG. 4 is a schematic representation of the drug solution shifter of the present invention. In the drawings, fig. 4a is a sample physical view in a non-pressurized state, wherein the three-way diverter 1, the two sets of dispensing needle assemblies 2 and the two sets of needle seal assemblies 3 are fixedly and hermetically connected with each other, and the dual chamber syringe 4 is not shown; fig. 4b is a sample physical diagram of the three-way diverter 1, the dispensing needle assembly 2 and the needle seal assembly 3 after being detached from each other, wherein the valve body 11 and the valve core 12 of the three-way diverter 1 are further detached; fig. 4c is a sample physical diagram of the three-way diverter 1.

Example 2

A medical fluid transfer system comprising: a three-way medical fluid transfer device operating in a closed loop as shown in fig. 1-4, and a pipetting connector 5 for fixedly connecting the medical fluid transfer device to a drug container as shown in fig. 5.

The pipetting connector 5 comprises a first sleeve 51 and a second sleeve 52 which are coaxial and connected to each other.

The first sleeve 51 is detachably sleeved on the front end of the sheath 31 of the medical fluid transfer device. Corresponding to the buckling platform of the front end outer wall of the sheath 31, two buckling grooves 55 are symmetrically arranged on the inner wall of the first sleeve 51, and the buckling grooves 55 are of an L-shaped structure formed by an axial groove and a transverse groove. When the sheath 31 is inserted into the first sleeve 51, the buckling table synchronously enters the axial groove of the buckling groove, and after the buckling table reaches a preset position, the sheath 31 or the liquid medicine transfer device is rotated to enable the buckling table to rotate into the transverse groove, so that the liquid medicine transfer device can be fixed with the pipetting connector 5.

The second sleeve 52 is adapted to be removably fitted over the mouth of the medicament container. The outer edge of the second sleeve 52 is symmetrically provided with axially forward extending snap fingers 53, and the rear end of each snap finger 53 is provided with a rearward extending release arm 54, the second sleeve 52 being secured to the container mouth by the snap fingers 53 and being detached from the container mouth by the release arms 54.

When the drug solution transfer device is fixedly connected to the drug container by the pipetting connector 5, the tip end surface of the seal 32 and the container mouth of the drug container are stably abutted in the sleeve.

Fig. 6 is a schematic cross-sectional view of the medical fluid transfer system in an operating state. As shown in the figure, the liquid medicine transfer device is fixedly connected with the medicine bottles a and B through the liquid transferring connector, and the front end surface of the sealing member 32 is stably abutted with the bottle mouth of the medicine bottle in the sleeve; the elastic member 33 is compressed and the dispensing needle 21 passes out of the closure 32 and into the vial; the sliding table is shifted into the transverse groove, and the needle head sealing assembly 3 is limited and fixed. At the same time, the spool 12 rotates toward the a side, and the inner ends of the first and second through chambers 121 and 122 communicate with the first and second through holes 111 and 112, respectively, of the a side.

The foregoing embodiments have described primarily the basic principles, principal features and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present invention, and various changes and modifications may be made without departing from the spirit and scope of the invention, which is defined in the appended claims.

Claims

1. A closed-loop, three-way medical fluid transfer device comprising: two groups of dispensing needle assemblies, two groups of needle head sealing assemblies and a three-way reverser for communicating the two groups of dispensing needle assemblies; the method is characterized in that:

The three-way commutator comprises a valve body and a valve core; wherein,

2. The three-way medical fluid transfer device of claim 1, wherein: the first joint and the second joint on the end face of the valve body are arranged in a manner as close as possible.

3. The three-way medical fluid transfer device of claim 1, wherein: the end face of the valve body is provided with a raised protective wing which surrounds the connector and forms a structure similar to a luer connector together with the connector, and the inner diameter of the protective wing is matched with the outer diameter of the rear end of the needle seat in the dispensing needle assembly.

4. The three-way medical fluid transfer device of claim 1, wherein: the outer side walls of the first connector and the second connector on the end face of the valve body are conical surfaces, and at least one annular boss is arranged on the conical surfaces; correspondingly, the shapes of the first connecting hole and the second connecting hole which are arranged at the rear end of the needle seat are respectively matched with the conical surfaces of the corresponding connectors, and the hole wall is provided with an annular groove corresponding to the annular boss.

5. The three-way medical fluid transfer device of claim 1, wherein: the valve cavity is arranged in the valve body in a centered manner perpendicular to the first through hole and the second through hole, and the axes of the first through hole, the second through hole and the valve cavity are positioned on the same plane.

6. The three-way medical fluid transfer device of claim 1, wherein: the middle section of the valve core is provided with a first neck groove along the radial direction, and the first neck groove is axially positioned between the inner port of the first conduction cavity and the inner port of the second conduction cavity; a second neck groove is arranged in the valve cavity at a corresponding position, and the second neck groove is positioned between the first through hole and the second through hole; and a sealing ring is arranged between the first neck groove and the second neck groove.

7. The three-way medical fluid transfer device of claim 1, wherein: the opening part of the valve cavity is provided with a coaxial annular groove with larger inner diameter, the valve core is provided with a baffle matched with the annular groove in structure, and a sealing gasket is arranged between the annular groove and the baffle to ensure the tightness between the annular groove and the baffle.

8. The three-way medical fluid transfer set according to claim 7, wherein: the outer edge of the annular groove of the valve body is provided with a clamping hook which is abutted against the baffle plate so as to fix the valve core on the valve body.

9. The three-way medical fluid transfer device of claim 1, wherein: the first connecting hole and the second connecting hole on the outer end face of the valve core are arranged adjacently and side by side.

10. The three-way medical fluid transfer machine according to claim 9, wherein: the connection hole is configured as Lu Erkong.

11. The three-way medical fluid transfer device of claim 1, wherein: the first conducting cavity is communicated with the first through holes on two sides at the same time under a specific position, and the second conducting cavity is communicated with the second through holes on two sides at the same time by changing the structures at the inner ends of the first conducting cavity and the second conducting cavity in the valve core.

12. The three-way medical fluid transfer device of claim 1, wherein: the medicine dispensing needle consists of an inner needle tube and an outer needle tube, the inner needle tube is arranged inside the outer needle tube in a penetrating mode, two ends of the inner needle tube extend out of the outer needle tube, at the moment, an inner column channel consists of an inner cavity of the inner needle tube, and a side ring channel consists of a cavity between the outer needle tube and the inner needle tube.

13. The three-way medical fluid transfer set according to claim 12, wherein: the front end of the outer needle tube is fixedly connected with the side wall of the front end of the inner needle tube in a closed manner.

14. The three-way medical fluid transfer set according to claim 13, wherein: the front end of the inner needle tube is provided with an inclined opening, or the front end of the inner needle tube is provided with a tip and a side opening; the front side wall of the outer needle tube is provided with a side opening.

15. The three-way medical fluid transfer device of claim 1, wherein: the front end of the needle seat is provided with a mounting groove, and a needle penetrating table with an appearance structure matched with the mounting groove is arranged in the mounting groove; the front end openings of the first channel and the second channel are positioned at the bottom of the mounting groove, and the front end opening of the first channel is coaxial with the dispensing needle; the needle penetrating table is internally provided with a front-back penetrating duct at the position corresponding to the shaft of the dispensing needle and is composed of a needle penetrating hole at the front part and a fixing hole at the rear part, wherein the needle penetrating hole is horn-shaped, the inner diameter of the needle penetrating hole gradually decreases from front to back until reaching the fixing hole, and the inner diameter of the fixing hole is matched with the outer diameter of the outer needle tube; the rear end surface of the needle threading platform is provided with a communication groove, and two ends of the communication groove are respectively communicated with the second channel and the fixed hole;

the rear end of the inner needle tube of the dispensing needle passes through the needle penetrating table and is fixed in the first channel in an embedded manner; the rear end of the outer needle tube is fixed in the fixing hole of the needle threading table in an embedded mode.

16. The three-way medical fluid transfer set according to claim 15, wherein: the first channel in the needle seat is arranged in a mode of being coaxial with the dispensing needle, and the second channel is arranged on one side of the first channel in parallel.

17. The three-way medical fluid transfer set according to claim 15, wherein: the cross section of the needle threading platform is non-circular and remains unchanged along the axial direction.

18. The three-way medical fluid transfer device of claim 1, wherein:

the needle seal assembly comprises a coaxially disposed sheath, a closure member, an elastic member and an inner sleeve, wherein:

19. The three-way medical fluid transfer machine of claim 18, wherein: the outer wall of the inner sleeve is provided with a buckle, a corresponding clamping hole is formed in the second barrel section of the sheath, and the fixed connection between the sheath and the inner sleeve is realized through the cooperation of the buckle and the clamping hole when the inner sleeve is inserted into the sheath.

20. The three-way medical fluid transfer machine of claim 18, wherein: the rear end port of the inner sleeve is provided with an annular boss in a radial outward mode, and when the front end face of the inner sleeve is abutted against the rear end face of the sealing piece, the annular boss at the rear end is exposed out of the sheath and is abutted against the rear end of the sheath.

21. The three-way medical fluid transfer machine of claim 18, wherein: the inner surface of the front end of the inner sleeve and the front end face of the needle seat are both provided with buckling structures, thereby realizing the fixed connection with the elastic piece.

22. The three-way medical fluid transfer machine of claim 18, wherein: the side of needle file is provided with the L shape recess that comprises axial groove and transverse groove, and the rear end of inner skleeve radially inwards is provided with the slip table, and the slip table imbeds in the L shape recess and can follow the recess and slide.

23. The three-way medical fluid transfer machine according to claim 1 or 18, wherein: the sealing piece is made of any one of rubber, silica gel and synthetic rubber.

24. The three-way medical fluid transfer machine according to claim 1 or 18, wherein: the front end face of the sealing piece protrudes out of the front end face of the sheath.

25. The three-way medical fluid transfer machine according to claim 1 or 18, wherein: the elastic member is an elastically folded tube or spring.

26. The three-way medical fluid transfer machine according to claim 1 or 18, wherein: the outer wall of the front end of the sheath is symmetrically provided with two buckling tables protruding outwards in the radial direction so as to be fixedly connected with the pipetting connector.

27. The three-way medical fluid transfer device of claim 1, wherein: the valve further comprises an external driving component which is connected with the first connecting hole and the second connecting hole which are arranged on the outer end face of the valve core.

28. The three-way medical fluid transfer set according to claim 27, wherein: the external driving component comprises a first injector and a second injector which are respectively communicated with a first connecting hole and a second connecting hole on the outer end face of the valve core.

29. The three-way medical fluid transfer set according to claim 27, wherein: the external driving component is a double-chamber injector and consists of a first injection cylinder, a first piston rod capable of sliding back and forth along an inner cavity in the first injection cylinder, a second injection cylinder and a second piston rod capable of sliding back and forth along the inner cavity in the second injection cylinder, wherein the first injection cylinder and the second injection cylinder are fixedly arranged in a side-by-side, same-direction and front-end flush manner; the front end face of the first injection cylinder is provided with a first joint, and the front end face of the second injection cylinder is provided with a second joint; the valve core and the double-chamber injector are fixedly and hermetically connected through the first connecting hole and the second connecting hole which are respectively embedded in the outer end face of the valve core by the first connector and the second connector.

30. The three-way medical fluid transfer set according to claim 29, wherein: the first connector and the second connector on the front end face of the injection tube are arranged in a manner as close as possible.

31. The three-way medical fluid transfer set according to claim 29, wherein: the outer side walls of the first connector and the second connector are conical surfaces, and at least one annular boss is arranged on the conical surfaces; correspondingly, the shapes of the first connecting hole and the second connecting hole on the outer end face of the valve core are respectively matched with the conical surfaces of the corresponding connectors, and the hole wall is provided with an annular groove corresponding to the annular boss.

32. The three-way medical fluid transfer set according to claim 29, wherein: the first and second connection holes on the outer end face of the valve core are configured as Lu Erkong, and the first and second fittings on the dual chamber syringe are configured as structurally matched first and second luer fittings.

33. A medical fluid transfer system comprising:

the three-way medical fluid transfer device of any one of claims 1-32, and a pipetting connector for fixedly connecting the medical fluid transfer device to a drug container;

34. The medical fluid transfer system of claim 33, wherein: the pipetting connector comprises a first sleeve and a second sleeve which are coaxial and are connected with each other, the first sleeve is used for being detachably sleeved at the front end of the sheath of the liquid medicine transfer device, the second sleeve is used for being detachably sleeved at the container mouth of the medicine container, and when the pipetting connector is fixedly connected, the front end face of the sealing piece and the container mouth of the medicine container are stably abutted in the sleeve.

35. The medical fluid transfer system of claim 34, wherein: the outer edge of the second sleeve is symmetrically provided with axially forward extending snap fingers, and the rear end of each snap finger is provided with a rearward extending release arm, by means of which the second sleeve is fixed to the container mouth and by means of which it is detached from the container mouth.

36. The medical fluid transfer system of claim 34, wherein: the inner wall of the first sleeve is symmetrically provided with two buckling grooves, the buckling grooves are of L-shaped structures consisting of axial grooves and transverse grooves, and correspondingly, the outer wall of the front end of the sheath is symmetrically provided with two buckling tables protruding outwards in the radial direction.