CN116115711A - Traditional Chinese medicine formula for treating rhinitis and liquid medicine thereof and preparation method of liquid medicine - Google Patents

Abstract

The invention relates to the field of traditional Chinese medicine formulas, in particular to a traditional Chinese medicine formula for treating rhinitis and a liquid medicine thereof and a preparation method thereof, wherein the traditional Chinese medicine formula comprises the following components in parts by mass: 5-10 parts of ephedra herb, 1-3 parts of asarum herb, 5-10 parts of magnolia flower, 5-10 parts of fructus xanthil, 10-15 parts of radix angelicae, 10-15 parts of radix sileris, 15-30 parts of astragalus membranaceus, 15-30 parts of radix codonopsis pilosulae, 15-30 parts of bighead atractylodes rhizome, 15-30 parts of poria cocos, 15-30 parts of prepared rehmannia root, 15-30 parts of Chinese yam, 5-10 parts of deer horn gum, 15-30 parts of medlar, 10-15 parts of radix aconiti lateralis preparata, 5-10 parts of dwarf lilyturf tuber, 5-10 parts of shizandra berry, 10-15 parts of Chinese angelica tail, 5-10 parts of pseudo-ginseng, 10-30 parts of wrinkled gianthyssop and 10-20 parts of yellow wine. The compound is prepared by adding and subtracting ephedra, aconite and asarum decoction, cocklebur fruit powder, chinese angelica and blood replenishing decoction and right-return pill, and has the effects of improving nasal obstruction and nasal discharge for a long time by warming and tonifying lung and kidney, tonifying qi and activating blood, dispelling cold and inducing resuscitation, improving the root cause of lung and kidney deficiency and cold, and regulating the symptoms of blood stasis and obstruction of collaterals.

Description

Traditional Chinese medicine formula for treating rhinitis and liquid medicine thereof and preparation method of liquid medicine

Technical Field

The invention relates to the field of traditional Chinese medicine formulas, in particular to a traditional Chinese medicine formula for treating rhinitis and a liquid medicine and a preparation method thereof.

Background

Chronic rhinitis and allergic rhinitis are clinical syndromes mainly manifested by alternative nasal obstruction with or without nasal discharge due to congestion and edema of nasal mucosa. The cause of rhinitis is complex, and the rhinitis is closely related to endocrine and immune dysfunction of the organism, abnormal anatomical structure (deflection of nasal septum), infection, local drug use and other factors. Long-term nasal obstruction and nasal discharge can lead to cerebral hypoxia of a patient, poor sleep quality, concentration failure, hypomnesis and influence on normal work and study, and meanwhile, the long-term oral breathing of the patient caused by night alternate nasal obstruction can cause tooth deformity, and diseases such as otitis media and the like are induced.

The treatment of rhinitis in modern medicine mainly comprises surgery, corticosteroids, antihistamines, vasoconstrictors and the like. Although these methods can improve symptoms of nasal obstruction and runny nose in a short time, nasal obstruction and runny nose are more serious before drug resistance, nasal dryness, nasal deformation and drug rhinitis occur, and rhinitis symptoms cannot be fundamentally improved.

Rhinitis is equivalent to the disease names of nasosinusitis, nasal asphyxia and the like in traditional Chinese medicine, and is mainly caused by deficiency-cold of the body, qi deficiency and blood stasis and obstruction of nasal orifices.

Disclosure of Invention

In order to solve the problems, the invention provides a traditional Chinese medicine formula for treating rhinitis, a liquid medicine thereof and a preparation method thereof, wherein the traditional Chinese medicine formula has the effects of warming and tonifying lung and kidney, tonifying qi and activating blood, dispelling cold and dredging orifices, and is used for treating chronic rhinitis and allergic rhinitis, which belongs to deficiency-cold blood stasis in the traditional Chinese medicine differentiation.

In order to achieve the above purpose, the invention adopts the following technical scheme: a traditional Chinese medicine formula for treating rhinitis is characterized in that: the composition comprises the following components in parts by mass: 5-10 parts of ephedra herb, 1-3 parts of asarum herb, 5-10 parts of magnolia flower, 5-10 parts of fructus xanthil, 10-15 parts of radix angelicae, 10-15 parts of radix sileris, 15-30 parts of astragalus membranaceus, 15-30 parts of radix codonopsis pilosulae, 15-30 parts of bighead atractylodes rhizome, 15-30 parts of poria cocos, 15-30 parts of prepared rehmannia root, 15-30 parts of Chinese yam, 5-10 parts of deer horn gum, 15-30 parts of medlar, 10-15 parts of radix aconiti lateralis preparata, 5-10 parts of dwarf lilyturf tuber, 5-10 parts of shizandra berry, 10-15 parts of Chinese angelica tail, 5-10 parts of pseudo-ginseng, 10-30 parts of wrinkled gianthyssop and 10-20 parts of yellow wine.

The liquid medicine is prepared from the traditional Chinese medicine formula for treating rhinitis and the mass parts.

The preparation method of the liquid medicine prepared by the traditional Chinese medicine formula for treating rhinitis is characterized by comprising the following steps:

s1, weighing 500-700 parts of water according to the weight part ratio, mixing with 10-15 parts of thin aconite, heating, decocting with strong fire until the mixture is boiled, and continuing to decoct with slow fire for 20-45 min;

s2, adding 5-10 parts of ephedra herb, 1-3 parts of asarum herb, 10 parts of magnolia flower, 5-10 parts of fructus xanthii, 10-15 parts of angelica dahurica, 10-15 parts of radix sileris, 15-30 parts of astragalus membranaceus, 15-30 parts of radix codonopsis pilosulae, 15-30 parts of bighead atractylodes rhizome, 15-30 parts of poria cocos, 15-30 parts of prepared rehmannia root, 15-30 parts of Chinese yam, 15-30 parts of medlar, 10-15 parts of light aconite, 5-10 parts of dwarf lilyturf tuber, 5-10 parts of shizandra berry, 10-15 parts of angelica sinensis, 10-30 parts of wrinkled gianthyssop herb, heating, decocting until boiling with strong fire for 20-45 min, stopping heating, filtering, and taking a first filtrate for standby;

s3, weighing 300-500 parts of water according to the weight portion ratio, adding the water into filter residues after the first filtrate is extracted, decocting with strong fire until the water is boiled, continuing to decoct with slow fire for 20-45 min, stopping heating, and filtering to obtain a second filtrate;

s4, mixing the first filtrate and the second filtrate to form a first mixed liquid medicine;

s5, weighing 10-20 parts by weight of yellow wine, boiling, pouring into the mixed liquid medicine prepared in the step S4, and uniformly stirring to form a second mixed liquid medicine;

and S6, weighing 5-10 parts of deer horn glue according to the weight part ratio, heating, melting, grinding 5-10 parts of pseudo-ginseng into powder, adding the processed deer horn glue and pseudo-ginseng into the second mixed liquid medicine, and uniformly stirring to obtain a finished product.

The invention has the beneficial effects that: rhinitis is equivalent to the disease names of nasosinusitis, nasal asphyxia and the like in traditional Chinese medicine, and is mainly caused by deficiency cold of the essence body (lung and kidney), qi deficiency, blood stasis and cold congealing in nasal orifices. The compound is prepared by adding and subtracting ephedra, aconite and asarum decoction, cocklebur fruit powder, chinese angelica and blood replenishing decoction and right-return pill, and has the effects of improving nasal obstruction and nasal discharge for a long time by warming and tonifying lung and kidney, tonifying qi and activating blood, dispelling cold and inducing resuscitation, improving the root cause of lung and kidney deficiency and cold, and regulating the symptoms of blood stasis and obstruction of collaterals.

Detailed Description

Example 1

A traditional Chinese medicine formula for treating deficiency-cold blood stasis type chronic rhinitis and allergic rhinitis comprises the following formula and mass parts: 5-10 parts of ephedra herb, 1-3 parts of asarum herb, 5-10 parts of magnolia flower, 5-10 parts of fructus xanthil, 10-15 parts of radix angelicae, 10-15 parts of radix sileris, 15-30 parts of astragalus membranaceus, 15-30 parts of radix codonopsis pilosulae, 15-30 parts of bighead atractylodes rhizome, 15-30 parts of poria cocos, 15-30 parts of prepared rehmannia root, 15-30 parts of Chinese yam, 5-10 parts of deer horn gum, 15-30 parts of medlar, 10-15 parts of radix aconiti lateralis preparata, 5-10 parts of dwarf lilyturf tuber, 5-10 parts of shizandra berry, 10-15 parts of Chinese angelica tail, 5-10 parts of pseudo-ginseng, 10-30 parts of wrinkled gianthyssop and 10-20 parts of yellow wine.

A preparation method of a liquid medicine prepared by a traditional Chinese medicine formula for treating deficiency-cold blood stasis type chronic rhinitis and allergic rhinitis comprises the following steps:

s1, weighing 700g of water, mixing with 15g of light aconite, heating, and decocting with strong fire until the water is boiled, and continuing to decoct with slow fire for 30min;

s2, adding 10g of ephedra herb, 3g of asarum herb, 10g of magnolia flower, 10g of fructus xanthii, 15g of radix angelicae, 15g of radix sileris, 30g of astragalus membranaceus, 30g of codonopsis pilosula, 30g of bighead atractylodes rhizome, 30g of poria cocos, 30g of prepared rehmannia root, 30g of Chinese yam, 30g of medlar, 15g of radix aconiti lateralis preparata, 10g of dwarf lilyturf tuber, 10g of Chinese magnoliavine fruit, 15g of Chinese angelica tail and 30g of wrinkled gianthyssop herb into the liquid medicine in the step S1, heating, decocting with strong fire until boiling and then continuously decocting with slow fire for 30min, stopping heating, filtering, and taking the first filtrate for standby;

s3, weighing 500g of water according to the weight g ratio, adding the water into filter residues after the first filtrate is extracted, decocting with strong fire until the water is boiled, continuing to decoct with slow fire for 30min, stopping heating, filtering, and taking the second filtrate;

s4, mixing the first filtrate and the second filtrate to form mixed liquid medicine;

s5, boiling 20ml of yellow wine, and pouring the mixed liquid medicine;

s6, weighing 5-10 parts of deer horn glue according to the weight portion ratio, heating, melting, grinding 5-10 parts of pseudo-ginseng into powder, adding the processed deer horn glue and pseudo-ginseng into the mixed liquid medicine, and uniformly stirring.

Example 2

A traditional Chinese medicine formula for treating deficiency-cold blood stasis type chronic rhinitis and allergic rhinitis comprises the following formula and mass parts: 5g of ephedra herb, 1g of asarum, 5g of magnolia flower, 5g of cocklebur fruit, 10g of angelica dahurica, 10g of divaricate saposhnikovia root, 15g of astragalus root, 15g of pilose asiabell root, 15g of largehead atractylodes rhizome, 15g of Indian buead, 15g of rehmannia glutinosa, 15g of Chinese yam, 5g of deer-horn gum, 15g of medlar, 10g of light aconite, 5g of dwarf lilyturf tuber, 5g of Chinese magnoliavine fruit, 10g of Chinese angelica tail, 5g of pseudo-ginseng and 10g of wrinkled gianthyssop.

A traditional Chinese medicine formula for treating deficiency-cold blood stasis type chronic rhinitis and allergic rhinitis comprises the following steps:

s1, weighing 500g of water according to the weight portion ratio, mixing with 10g of light aconite, heating, and decocting with strong fire until the water is boiled, and continuing to decoct with slow fire for 30min;

s2, adding 5g of ephedra herb, 1g of asarum herb, 5g of magnolia flower, 5g of fructus xanthii, 10g of radix angelicae, 10g of radix sileris, 15g of astragalus membranaceus, 15g of codonopsis pilosula, 15g of bighead atractylodes rhizome, 15g of poria cocos, 15g of prepared rehmannia root, 15g of Chinese yam, 15g of medlar, 10g of light aconite, 5g of dwarf lilyturf tuber, 5g of Chinese magnoliavine fruit, 10g of Chinese angelica tail and 10g of wrinkled gianthyssop herb into the liquid medicine in the step S1, heating, decocting with strong fire until boiling and then continuously decocting with slow fire for 30min, stopping heating, filtering, and taking the first filtrate for standby;

s3, weighing 300g of water according to the weight portion ratio, adding the water into filter residues after the first filtrate is extracted, decocting with strong fire until the water is boiled, continuing to decoct with slow fire for 30min, stopping heating, filtering, and taking the second filtrate;

s4, mixing the first filtrate and the second filtrate to form mixed liquid medicine;

s5, boiling 10ml of yellow wine, and pouring the mixed liquid medicine;

s6, weighing 5g of deer horn gelatin according to the weight portion ratio, heating, melting, pulverizing 5g of pseudo-ginseng, adding the processed deer horn gelatin and pseudo-ginseng into the mixed liquid medicine, and uniformly stirring.

Application method

The obtained medicinal liquid is taken at 1 hr after breakfast and supper twice.

The ephedra herb, asarum herb and the light accessory tablet adopted by the recipe are all the formulas of 'ephedra herb, aconite root and asarum herb soup' in shaoyin from typhoid fever theory, and have the effects of warming channels and relieving exterior syndrome, and supporting yang and relieving exterior syndrome. Modern researches have shown that this recipe can shrink the blood vessels of the nasal mucosa, improve nasal ventilation and reduce nasal discharge secretion, whereas the light aconite has the efficacy of warming yang and dispelling cold, so that this recipe is especially suitable for chronic rhinitis which is a cold syndrome.

The flos Magnoliae, fructus Xanthii, radix Angelicae Dahuricae and radix Saposhnikoviae are prepared by removing herba Menthae and preventing efflorescence from "fructus Xanthii powder" in the "re-established Jisheng prescription", and have the effects of dispelling pathogenic wind and warming and relieving stuffy nose. Modern medical research shows that dahurian angelica root and ledebouriella root have strong antiallergic effect. The fructus Xanthii powder and the ephedra, aconite and asarum Shang Geyong have the synergistic effect of warming yang, dispelling cold and inducing resuscitation.

The astragalus root, the angelica tail and the pseudo-ginseng are added into the angelica blood-replenishing decoction of internal and external injury differentiation, and the Chinese medicinal composition is prepared by adding pseudo-ginseng into the decoction for dissolving. The astragalus root has the effects of warming and invigorating qi of lung and spleen, chinese angelica tail and pseudo-ginseng have the effects of activating blood and dissolving stasis, and the three medicines are used together to achieve the effects of tonifying qi and activating blood, so that the Chinese medicine is particularly suitable for long-term nasal obstruction, left and right alternation and symptoms of light day, light night and heavy weight caused by long-term rhinitis, qi and blood loss and qi deficiency and blood stasis. Modern researches have also shown that astragalus root, chinese angelica root, notoginseng, etc. can improve the edema and congestion of nasal mucosa and reduce the release of inflammatory factors.

The prepared rhizome of rehmannia, chinese yam, deer-horn glue and medlar adopted by the method are prepared by the method of right-returning pill preparation in Jingyue full book. The treatment of the type of syndromes: the lung is the main part of qi, the kidney is the root of qi, the lung governs qi output, the kidney governs qi receiving, yin and yang intersect, and respiration is the sum. The lung and kidney are treated simultaneously due to deficiency of both lung and kidney in pathological condition, so there is a theory of homology of lung and kidney. Clinically, most rhinitis patients feel wind-cold, nasal obstruction, nasal discharge and persistent, aggravate in winter and spring and relieve in summer and autumn, and lung and kidney deficiency often occurs. On the basis of dispelling cold and tonifying lung, the treatment is often better in curative effect by adding medicaments for tonifying lung and kidney. In the recipe, rehmannia root, chinese yam, deer-horn gum and wolfberry fruit all have the effects of warming and tonifying lung and kidney, and deer-horn gum is a blood and meat-like product, and is suitable for patients with chronic rhinitis with repeated attacks of nasal obstruction and nasal discharge and aggravated cold.

The radix codonopsis pilosulae, the bighead atractylodes rhizome, the poria cocos and the agastache rugosus are prepared from four monarch drug decoction, liquorice and agastache rugosus in the formula of Taiping Huimin He Ji Ju. Has effects of invigorating qi, invigorating spleen, and eliminating dampness. The above warm lung and kidney tonifying drugs are too greasy and may cause gastrointestinal dysfunction. The codonopsis pilosula and bighead atractylodes rhizome can invigorate the spleen, the poria cocos and the wrinkled gianthyssop herb can harmonize the spleen and the stomach, promote transportation and transformation, enable the medicine for warming and activating to exert the due efficacy, and also play a role of 'tonifying earth and generating gold'.

The dwarf lilyturf tuber and the schisandra chinensis in the recipe have the effects of nourishing yin, moisturizing the lung, tonifying qi and calming the heart. The nasal obstruction of patients suffering from rhinitis is not easy to occur, people have to feel tired, the nasal obstruction can cause the loss of yin fluid of a human body by breathing through mouth, and in addition, the medicines for nourishing yin, moisturizing lung and calming heart have a certain effect on improving dry mouth, tongue and vexation and insomnia caused by breathing through mouth in patients suffering from rhinitis by taking the medicines for a long time, so that the medicines for treating the warm dryness are less adjunctive to nourish yin, moisten lung and calm heart strengthen the whole formula curative effect.

The yellow wine has the effects of relieving fever, warming stomach, moistening skin, nourishing spleen qi, etc., and can strengthen the effect of Fang Wenjing in dispelling cold and dredging collaterals, and reduce irritation of medicine to gastrointestinal tract.

In summary, rhinitis is equivalent to the disease names of nasosinusitis, nasal asphyxia and the like in traditional Chinese medicine, and the invention provides essence deficiency cold (lung and kidney) based on early clinical practice, and qi deficiency and blood stasis, and cold congealing nasal orifices are the main traditional Chinese medicine pathogenesis of the disease. The compound is prepared by adding, modifying and cutting ephedra, aconite and asarum decoction, cocklebur fruit powder, chinese angelica and blood supplementing decoction, four monarch drugs, right-return pills and the like, and has the effects of warming kidney and tonifying lung, tonifying qi and activating blood, dispelling cold and dredging orifices, improving the root cause of lung and kidney deficiency and cold, regulating the symptoms of blood stasis and obstruction of collaterals, leading the orifices to be dredging, reducing nasal discharge and obtaining the effect of permanently improving nasal obstruction and nasal discharge.

Clinical cases

Patient Ma Mou, male, 40 years old, case number: 60464757, complain of "chronic rhinitis for 20 years, intermittent nasal obstruction and nasal discharge for more than 20 years". The patient has nasal obstruction and nasal discharge after cold before 20 years, and then the symptoms are improved after nasal drops are used by himself, but the symptoms are aggravated gradually and are difficult to breathe, the external hospital is diagnosed with the drug hypertrophic rhinitis, and the external hospital is treated by excision of the lower nasal nail part, microwave ablation, budesonide spray, azelastine hydrochloride nasal spray, traditional Chinese medicine and the like, and the symptoms are repeated, aggravated in the night, autumn and winter and improved in spring and summer. Nasal obstruction symptoms are improved after surgery due to nasal obstruction aggravation in the outside hospital examination, nasal septum deflection is considered, nasal septum correction and lower turbinate forming are performed, and nasal obstruction is the same after 3 months.

The symptoms of the diagnosis are as follows: nasal obstruction, clear nasal discharge, aggravation at night, alternative nasal obstruction of the nose at both sides, poor sleep, open mouth and breath, dry mouth, plain feeling, cold feeling of limbs, even cold below the waist, easy cold, poor sleep, anorexia, clear and long urine, convenient use, pale and purple tongue, white coating and wiry pulse. Western diagnosis: chronic rhinitis (post-combination therapy); diagnosis of traditional Chinese medicine: syndrome of deficiency cold and blood stasis in nose.

After the rhinitis prescription is decocted with water for administration, the nasal obstruction and nasal discharge of a patient are obviously improved, the limbs are cooled and the mouth is dry, the sleeping quality is obviously improved, and the symptoms are stable after the traditional Chinese medicine is taken for half a year, so that the aim of improving the symptoms is fulfilled.

The above embodiments are merely illustrative of the preferred embodiments of the present invention and are not intended to limit the scope of the present invention, and various modifications and improvements made by those skilled in the art to the technical solution of the present invention should fall within the scope of protection defined by the claims of the present invention without departing from the spirit of the design of the present invention.

Claims (3)

1. A traditional Chinese medicine formula for treating rhinitis is characterized in that: the composition comprises the following components in parts by mass: 5-10 parts of ephedra herb, 1-3 parts of asarum herb, 5-10 parts of magnolia flower, 5-10 parts of fructus xanthil, 10-15 parts of radix angelicae, 10-15 parts of radix sileris, 15-30 parts of astragalus membranaceus, 15-30 parts of radix codonopsis pilosulae, 15-30 parts of bighead atractylodes rhizome, 15-30 parts of poria cocos, 15-30 parts of prepared rehmannia root, 15-30 parts of Chinese yam, 5-10 parts of deer horn gum, 15-30 parts of medlar, 10-15 parts of radix aconiti lateralis preparata, 5-10 parts of dwarf lilyturf tuber, 5-10 parts of shizandra berry, 10-15 parts of Chinese angelica tail, 5-10 parts of pseudo-ginseng, 10-30 parts of wrinkled gianthyssop and 10-20 parts of yellow wine.

2. A liquid medicine prepared by a traditional Chinese medicine formula for treating rhinitis is characterized in that: the formula and the mass parts of the composition are prepared according to the formula and the mass parts of the composition in claim 1.

3. The preparation method of the liquid medicine prepared by the traditional Chinese medicine formula for treating rhinitis is characterized by comprising the following steps:

s1, weighing 500-700 parts of water according to the weight part ratio, mixing with 10-15 parts of thin aconite, heating, decocting with strong fire until the mixture is boiled, and continuing to decoct with slow fire for 20-45 min;

s2, adding 5-10 parts of ephedra herb, 1-3 parts of asarum herb, 5-10 parts of magnolia flower, 5-10 parts of cocklebur fruit, 10-15 parts of angelica dahurica, 10-15 parts of radix sileris, 15-30 parts of astragalus membranaceus, 15-30 parts of codonopsis pilosula, 15-30 parts of bighead atractylodes rhizome, 15-30 parts of poria cocos, 15-30 parts of rehmannia glutinosa, 15-30 parts of Chinese yam, 15-30 parts of medlar, 10-15 parts of thin aconite, 5-10 parts of dwarf lilyturf tuber, 5-10 parts of schisandra chinensis, 10-15 parts of angelica sinensis, 10-30 parts of wrinkled gianthyssop herb, heating, continuously decocting until boiling with strong fire for 20-45 min, stopping heating, filtering, and taking the first filtrate for standby;

s3, weighing 300-500 parts of water according to the weight portion ratio, adding the water into filter residues after the first filtrate is extracted, decocting with strong fire until the water is boiled, continuing to decoct with slow fire for 20-45 min, stopping heating, and filtering to obtain a second filtrate;

s4, mixing the first filtrate and the second filtrate to form a first mixed liquid medicine;

s5, weighing 10-20 parts by weight of yellow wine, boiling, pouring into the mixed liquid medicine prepared in the step S4, and uniformly stirring to form a second mixed liquid medicine;

and S6, weighing 5-10 parts of deer horn glue according to the weight part ratio, heating, melting, grinding 5-10 parts of pseudo-ginseng into powder, adding the processed deer horn glue and pseudo-ginseng into the second mixed liquid medicine, and uniformly stirring to obtain a finished product.