CN116115674A - Traditional Chinese medicine formula for treating proteinuria - Google Patents

Traditional Chinese medicine formula for treating proteinuria Download PDF

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CN116115674A
CN116115674A CN202310102061.8A CN202310102061A CN116115674A CN 116115674 A CN116115674 A CN 116115674A CN 202310102061 A CN202310102061 A CN 202310102061A CN 116115674 A CN116115674 A CN 116115674A
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王琳
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
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    • A61P13/00Drugs for disorders of the urinary system
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
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Abstract

The invention relates to the technical field of proteinuria and discloses a traditional Chinese medicine formula for treating proteinuria, which comprises the following raw materials in parts by mass: 15-20 parts of baical skullcap root, 20-25 parts of coptis root, 20-30 parts of Indian buead, 20-25 parts of cassia bark, 30-35 parts of astragalus root, 10-15 parts of leech, 15-25 parts of black cis tablet, 10-12 parts of rhubarb, 20-22 parts of largehead atractylodes rhizome, 15-18 parts of gordon euryale seed, 18-25 parts of dried ginger, 20-30 parts of honey-fried licorice root, 25-30 parts of liquorice root and 30-35 parts of Chinese yam.

Description

Traditional Chinese medicine formula for treating proteinuria
Technical Field
The invention belongs to the technical field of proteinuria, and particularly relates to a traditional Chinese medicine formula for treating proteinuria.
Background
Clinical medicine shows that proteinuria is closely related to diabetes mellitus, and the proteinuria is a phenomenon of diabetes mellitus, clinically manifested by albuminuria, edema, hypertension, renal insufficiency and the like, and pathologically manifested by glomerular basement membrane thickening and extracellular matrix accumulation mainly in mesangial regions, often accompanied by renal vascular and tubular interstitial lesions, and finally caused glomerulosclerosis and renal interstitial fibrosis. The pathological manifestations are closely related to the disease progress of diabetic kidney disease;
the traditional Chinese medicine considers that proteinuria is caused by diabetes mellitus which is not healed for a long time, so that sugar toxin is diffused, and various pathological products are mixed at the same time, kidney collaterals are damaged, and kidney collaterals are formed, so that diabetes mellitus and kidney diseases are caused.
On one hand, the sugar toxin affects the vital qi and viscera functions of a human body, and at the beginning, qi is damaged, yin is consumed, and yin is damaged for a long time, so that deficiency of both qi, blood, yin and yang is caused; on the other hand, the direct injury of sugar toxin to kidney collaterals is followed by cementing and accumulating kidney collaterals by pathological products (such as qi stagnation, heat stagnation, phlegm dampness, blood stasis and the like) to form kidney collaterals abdominal mass; early kidney pathogenesis features such as distention of collaterals, swelling of collaterals, qi stagnation and heat stagnation, and increased kidney volume and glomerular filtration rate corresponding to clinical manifestations; the kidney disease in the middle stage is characterized by obstruction of collaterals, mainly phlegm dampness, water dampness or damp-heat, blood stasis, proteinuria and edema, and kidney pathology is hyperplasia of mesangial matrix, thickening of basal lamina, nodular sclerosis and the like; late kidney pathogenesis is characterized by accumulation of collaterals and collaterals, which form abdominal mass, mainly due to decline of kidney-qi and accumulation of turbid toxin, and kidney pathology is glomerulosclerosis and renal interstitial tubular fibrosis.
However, in the current market, western medicine treatment is mostly adopted for relieving proteinuria, and the problems of the kidneys of the body cannot be essentially solved, so that the effects of the western medicine are poor, and meanwhile, the western medicine can generate larger side effects to cause medicine accumulation, so that the kidney is damaged by the medicine.
Disclosure of Invention
In view of the above, in order to overcome the defects of the prior art, the invention provides a novel traditional Chinese medicine formula for treating proteinuria, which can directly act on kidneys through traditional Chinese medicines, and effectively solves the problem that western medicines cannot be used for essentially solving the problems of kidneys.
The invention is realized by the following technical scheme:
a traditional Chinese medicine formula for treating proteinuria effectively solves the problems in the background technology.
In order to achieve the above purpose, the present invention provides the following technical solutions: a traditional Chinese medicine formula for treating proteinuria comprises the following raw materials in parts by mass: 15-20 parts of radix scutellariae, 20-25 parts of coptis chinensis, 20-30 parts of poria cocos, 20-25 parts of cinnamon, 30-35 parts of astragalus membranaceus, 10-15 parts of leech, 15-25 parts of black cis tablet, 10-12 parts of rheum officinale, 20-22 parts of bighead atractylodes rhizome, 15-18 parts of semen euryales, 18-25 parts of dried ginger, 20-30 parts of honey-fried licorice root, 25-30 parts of liquorice and 30-35 parts of Chinese yam.
Preferably, the preparation of the traditional Chinese medicine formula comprises the following steps:
s1, preparing medicinal powder: putting radix Scutellariae, rhizoma Coptidis, poria, cortex Cinnamomi, radix astragali, hirudo, HEISAN tablet, radix Et rhizoma Rhei, rhizoma Atractylodis Macrocephalae, semen euryales, rhizoma Zingiberis, radix Glycyrrhizae Preparata and radix Glycyrrhizae into a traditional Chinese medicine pulverizing device, starting the pulverizing device, pulverizing the above materials into powder, sieving, and repeatedly grinding large-particle powder to obtain fine-particle powder;
s2, dissolving medicinal materials: placing the fine granular medicinal material powder into a heating container, adding warm water into the heating container, stirring, continuously adding water, stirring, and heating the heating container until the dissolved medicinal material emits strong medicinal fragrance;
s3, slow decocting medicinal materials: covering the heating container with a cover body, and reducing the heating temperature of the heating container until the volume of the solution in the heating container becomes half of the original volume of the solution;
s4, filtering residues and collecting liquid medicine: pouring the liquid medicine into a filtering device, separating the liquid medicine from the residue by separation of the filtering device, and filling the liquid medicine into a collecting container;
s5, preparing turbid liquid: peeling fresh rhizoma Dioscoreae, mashing into paste, adding the collected medicinal liquid into mashing container, stirring until the medicinal liquid is completely mixed with rhizoma Dioscoreae slurry to form turbid liquid, adding edible gelatinizer into turbid liquid, heating, and cooling and shaping;
s6, packaging: packaging the above materials into pill, and bottling.
Preferably, in the step S2, the medicinal material is dissolved, the total mass of water added into the heating container is 5 times of the weight of the medicinal material powder, and the specific gravity of the added warm water in the total mass of water is 2:5.
Preferably, the S4 process filters the residue, collects the liquid medicine, and after separating the liquid medicine from the residue, collects the residue at the same time, and filters the liquid medicine in the residue by multiple purification.
Preferably, in the step S5, the turbid liquid is prepared, the turbid liquid is heated, the heating temperature is controlled to be 80-100 ℃, the heating time is controlled to be 15-30min, and specific problems and time are calculated according to the specific adding dosage.
Preferably, the raw materials of the traditional Chinese medicine formula comprise the following components in percentage by mass: 20 parts of baical skullcap root, 25 parts of coptis root, 30 parts of Indian buead, 22 parts of cassia bark, 30 parts of membranous milkvetch root, 12 parts of leech, 15 parts of Heishan tablet, 12 parts of rhubarb, 22 parts of largehead atractylodes rhizome, 18 parts of gorgon euryale seed, 25 parts of dried ginger, 25 parts of honey-fried licorice root, 30 parts of liquoric root and 35 parts of Chinese yam.
Compared with the prior art, the invention has the beneficial effects that:
in operation, through the mutual coordination of western medicines, after the administration of a patient, the Chinese medicine can directly act on kidney organs of the patient, so that the problem of kidney appearance is essentially solved, the efficacy of the medicine is improved, and meanwhile, the use of the Chinese medicine does not generate side effects, thereby being beneficial to the maintenance of the medicine on the kidney.
Drawings
The accompanying drawings are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate the invention and together with the embodiments of the invention, serve to explain the invention. In the drawings:
FIG. 1 is a schematic flow chart of a traditional Chinese medicine formula;
Detailed Description
The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the invention; all other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the first embodiment, as shown in fig. 1, the invention comprises a traditional Chinese medicine formula for treating proteinuria, wherein the raw materials of the traditional Chinese medicine formula comprise the following components in percentage by mass: 20 parts of radix scutellariae, 25 parts of coptis chinensis, 30 parts of poria cocos, 22 parts of cinnamon, 30 parts of astragalus mongholicus, 12 parts of leech, 15 parts of black cis tablet, 12 parts of rheum officinale, 22 parts of bighead atractylodes rhizome, 18 parts of semen euryales, 25 parts of dried ginger, 25 parts of honey-fried licorice root, 30 parts of liquorice and 35 parts of Chinese yam;
a traditional Chinese medicine formula for treating proteinuria, the preparation of the traditional Chinese medicine formula comprises the following steps:
s1, preparing medicinal powder: putting radix Scutellariae, rhizoma Coptidis, poria, cortex Cinnamomi, radix astragali, hirudo, HEISAN tablet, radix Et rhizoma Rhei, rhizoma Atractylodis Macrocephalae, semen euryales, rhizoma Zingiberis, radix Glycyrrhizae Preparata and radix Glycyrrhizae into a traditional Chinese medicine pulverizing device, starting the pulverizing device, pulverizing the above materials into powder, sieving, and repeatedly grinding large-particle powder to obtain fine-particle powder;
s2, dissolving medicinal materials: placing the fine granular medicinal material powder into a heating container, adding warm water into the heating container, stirring, continuously adding water, stirring, and heating the heating container until the dissolved medicinal material emits strong medicinal fragrance; s2, dissolving medicinal materials, wherein the total mass of water added into a heating container is 5 times of the weight of medicinal material powder, and the proportion of the mass of warm water added into the heating container to the total mass of water is 2:5;
s3, slow decocting medicinal materials: covering the heating container with a cover body, and reducing the heating temperature of the heating container until the volume of the solution in the heating container becomes half of the original volume of the solution;
s4, filtering residues and collecting liquid medicine: pouring the liquid medicine into a filtering device, separating the liquid medicine from the residue by separation of the filtering device, and filling the liquid medicine into a collecting container; s4, filtering the residues, collecting the liquid medicine, separating the liquid medicine from the residues, collecting the residues at the same time, and filtering the liquid medicine in the residues by adopting a mode of multiple purification;
s5, preparing turbid liquid: peeling fresh rhizoma Dioscoreae, mashing into paste, adding the collected medicinal liquid into mashing container, stirring until the medicinal liquid is completely mixed with rhizoma Dioscoreae slurry to form turbid liquid, adding edible gelatinizer into turbid liquid, heating, and cooling and shaping; s5, preparing turbid liquid, heating the turbid liquid, controlling the heating temperature to be 80-100 ℃, controlling the heating time to be 15-30min, and calculating specific problems and time according to specific added dosage;
s6, packaging: packaging the above materials into pill, and bottling.
In the second embodiment, as shown in fig. 1, the invention comprises a traditional Chinese medicine formula for treating proteinuria, wherein the raw materials of the traditional Chinese medicine formula comprise the following components in percentage by mass: 18 parts of radix scutellariae, 20 parts of coptis chinensis, 20 parts of poria cocos, 20 parts of cinnamon, 32 parts of astragalus mongholicus, 10 parts of leech, 15 parts of black cis tablet, 10 parts of rheum officinale, 20 parts of bighead atractylodes rhizome, 15 parts of semen euryales, 18 parts of dried ginger, 20 parts of honey-fried licorice root, 25 parts of liquorice and 30 parts of Chinese yam;
a traditional Chinese medicine formula for treating proteinuria, the preparation of the traditional Chinese medicine formula comprises the following steps:
s1, preparing medicinal powder: putting radix Scutellariae, rhizoma Coptidis, poria, cortex Cinnamomi, radix astragali, hirudo, HEISAN tablet, radix Et rhizoma Rhei, rhizoma Atractylodis Macrocephalae, semen euryales, rhizoma Zingiberis, radix Glycyrrhizae Preparata and radix Glycyrrhizae into a traditional Chinese medicine pulverizing device, starting the pulverizing device, pulverizing the above materials into powder, sieving, and repeatedly grinding large-particle powder to obtain fine-particle powder;
s2, dissolving medicinal materials: placing the fine granular medicinal material powder into a heating container, adding warm water into the heating container, stirring, continuously adding water, stirring, and heating the heating container until the dissolved medicinal material emits strong medicinal fragrance; s2, dissolving medicinal materials, wherein the total mass of water added into a heating container is 5 times of the weight of medicinal material powder, and the proportion of the mass of warm water added into the heating container to the total mass of water is 2:4;
s3, slow decocting medicinal materials: covering the heating container with a cover body, and reducing the heating temperature of the heating container until the volume of the solution in the heating container becomes half of the original volume of the solution;
s4, filtering residues and collecting liquid medicine: pouring the liquid medicine into a filtering device, separating the liquid medicine from the residue by separation of the filtering device, and filling the liquid medicine into a collecting container; s4, filtering the residues, collecting the liquid medicine, separating the liquid medicine from the residues, collecting the residues at the same time, and filtering the liquid medicine in the residues by adopting a mode of multiple purification;
s5, preparing turbid liquid: peeling fresh rhizoma Dioscoreae, mashing into paste, adding the collected medicinal liquid into mashing container, stirring until the medicinal liquid is completely mixed with rhizoma Dioscoreae slurry to form turbid liquid, adding edible gelatinizer into turbid liquid, heating, and cooling and shaping; s5, preparing turbid liquid, heating the turbid liquid, controlling the heating temperature to be 80-100 ℃, controlling the heating time to be 20min, and calculating specific problems and time according to specific added dosage;
s6, packaging: packaging the above materials into pill, and bottling.
The licorice has sweet taste and flat nature, has the effects of tonifying qi and strengthening the middle warmer, moistening lung and relieving cough, and harmonizing drug property, can regulate symptoms such as spleen deficiency and burnout, heart deficiency and palpitation, limb spasm and the like, can regulate stomach and intestine, has good intestinal tract, and is favorable for the absorption of drugs by the intestinal tract.
The Chinese yam has sweet taste and flat nature, has the effects of tonifying qi, tonifying spleen, lung, kidney and the like, can regulate the symptoms of spleen deficiency, anorexia, lung deficiency cough and asthma, internal heat diabetes and the like, can help gastrointestinal digestion, has good intestinal tract, has viscosity and can shape the medicament.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. A traditional Chinese medicine formula for treating proteinuria is characterized in that: the traditional Chinese medicine formula comprises the following raw materials in percentage by mass: 15-20 parts of radix scutellariae, 20-25 parts of coptis chinensis, 20-30 parts of poria cocos, 20-25 parts of cinnamon, 30-35 parts of astragalus membranaceus, 10-15 parts of leech, 15-25 parts of black cis tablet, 10-12 parts of rheum officinale, 20-22 parts of bighead atractylodes rhizome, 15-18 parts of semen euryales, 18-25 parts of dried ginger, 20-30 parts of honey-fried licorice root, 25-30 parts of liquorice and 30-35 parts of Chinese yam.
2. The traditional Chinese medicine formula for treating proteinuria according to claim 1, wherein the traditional Chinese medicine formula is characterized in that: the preparation of the traditional Chinese medicine formula comprises the following steps:
s1, preparing medicinal powder: putting radix Scutellariae, rhizoma Coptidis, poria, cortex Cinnamomi, radix astragali, hirudo, HEISAN tablet, radix Et rhizoma Rhei, rhizoma Atractylodis Macrocephalae, semen euryales, rhizoma Zingiberis, radix Glycyrrhizae Preparata and radix Glycyrrhizae into a traditional Chinese medicine pulverizing device, starting the pulverizing device, pulverizing the above materials into powder, sieving, and repeatedly grinding large-particle powder to obtain fine-particle powder;
s2, dissolving medicinal materials: placing the fine granular medicinal material powder into a heating container, adding warm water into the heating container, stirring, continuously adding water, stirring, and heating the heating container until the dissolved medicinal material emits strong medicinal fragrance;
s3, slow decocting medicinal materials: covering the heating container with a cover body, and reducing the heating temperature of the heating container until the volume of the solution in the heating container becomes half of the original volume of the solution;
s4, filtering residues and collecting liquid medicine: pouring the liquid medicine into a filtering device, separating the liquid medicine from the residue by separation of the filtering device, and filling the liquid medicine into a collecting container;
s5, preparing turbid liquid: peeling fresh rhizoma Dioscoreae, mashing into paste, adding the collected medicinal liquid into mashing container, stirring until the medicinal liquid is completely mixed with rhizoma Dioscoreae slurry to form turbid liquid, adding edible gelatinizer into turbid liquid, heating, and cooling and shaping;
s6, packaging: packaging the above materials into pill, and bottling.
3. The traditional Chinese medicine formula for treating proteinuria according to claim 1, wherein the traditional Chinese medicine formula is characterized in that: and S2, dissolving medicinal materials, wherein the total mass of water added into a heating container is 5 times of the weight of medicinal material powder, and the proportion of the mass of warm water added into the heating container to the total mass of water is 2:5.
4. The traditional Chinese medicine formula for treating proteinuria according to claim 1, wherein the traditional Chinese medicine formula is characterized in that: and S4, filtering the medicine residues, collecting the medicine liquid, separating the medicine liquid from the medicine residues, collecting the medicine residues at the same time, and filtering the medicine liquid in the medicine residues by adopting a mode of purifying for multiple times.
5. The traditional Chinese medicine formula for treating proteinuria according to claim 1, wherein the traditional Chinese medicine formula is characterized in that: and S5, preparing turbid liquid, heating the turbid liquid, controlling the heating temperature to be 80-100 ℃, controlling the heating time to be 15-30min, and calculating specific problems and time according to the specific adding dosage.
6. The traditional Chinese medicine formula for treating proteinuria according to claim 1, wherein the traditional Chinese medicine formula is characterized in that: the traditional Chinese medicine formula comprises the following raw materials in percentage by mass: 20 parts of baical skullcap root, 25 parts of coptis root, 30 parts of Indian buead, 22 parts of cassia bark, 30 parts of membranous milkvetch root, 12 parts of leech, 15 parts of Heishan tablet, 12 parts of rhubarb, 22 parts of largehead atractylodes rhizome, 18 parts of gorgon euryale seed, 25 parts of dried ginger, 25 parts of honey-fried licorice root, 30 parts of liquoric root and 35 parts of Chinese yam.
CN202310102061.8A 2023-02-13 2023-02-13 Traditional Chinese medicine formula for treating proteinuria Pending CN116115674A (en)

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