CN116109628A

CN116109628A - Method and device for constructing bone defect prosthesis and storage medium

Info

Publication number: CN116109628A
Application number: CN202310372686.6A
Authority: CN
Inventors: 田耘; 刘冰川; 李健; 苏永琳; 刘敏
Original assignee: Peking University Third Hospital Peking University Third Clinical Medical College; Beijing AK Medical Co Ltd
Current assignee: Peking University Third Hospital Peking University Third Clinical Medical College; Beijing AK Medical Co Ltd
Priority date: 2023-04-10
Filing date: 2023-04-10
Publication date: 2023-05-12
Anticipated expiration: 2043-04-10
Also published as: CN116109628B

Abstract

The application discloses a construction method, a construction device and a storage medium of a bone defect prosthesis. Wherein the method comprises the following steps: acquiring a medical image of a target object; determining affected side bone reconstruction data and healthy side bone reconstruction data of a long bone part in a target object based on the medical image; determining defect part information of the long bone part based on the affected side bone reconstruction data and the healthy side bone reconstruction data; based on the defect site information, a bone defect prosthesis of the target object is constructed. The method solves the technical problem that the bone defect prosthesis cannot be accurately constructed.

Description

Method and device for constructing bone defect prosthesis and storage medium

Technical Field

The present application relates to the field of medicine, and in particular, to a method, apparatus and storage medium for constructing a bone defect prosthesis.

Background

Currently, traumatic, osteomyelitis and bone neoplastic bone defects are not uncommon clinically and have been a major concern for traumatic orthopedics. Bone defect problems caused by osteomyelitis, trauma, tumors, etc. are clinically common and very troublesome diseases.

In the related art, a tumor prosthesis is usually adopted, but the method needs to completely remove bone residues at the metaphyseal end, damages a natural joint surface with normal functions, causes larger trauma to a patient, causes certain loss of the natural functions of the patient, and still has the technical problem that the bone defect prosthesis cannot be accurately constructed.

Aiming at the technical problem that the bone defect prosthesis cannot be accurately constructed, no effective solution is proposed at present.

Disclosure of Invention

The embodiment of the application provides a construction method, a construction device and a storage medium of a bone defect prosthesis, which at least solve the technical problem that the bone defect prosthesis cannot be constructed accurately.

According to one aspect of embodiments of the present application, there is provided a method of constructing a bone defect prosthesis, comprising: acquiring a medical image of a target object; determining affected side bone reconstruction data and healthy side bone reconstruction data of a long bone part in a target object based on the medical image; determining defect part information of the long bone part based on the affected side bone reconstruction data and the healthy side bone reconstruction data; based on the defect site information, a bone defect prosthesis of the target object is constructed.

Optionally, determining defect site information for the long bone site based on the affected side bone reconstruction data and the healthy side bone reconstruction data includes: mirror image processing is carried out on the bone reconstruction data of the healthy side; and determining defect position information based on the mirrored healthy side bone reconstruction data and the affected side bone reconstruction data.

Optionally, determining defect site information for the long bone site based on the mirrored healthy-side bone reconstruction data and the diseased-side bone reconstruction data, comprising: matching and fitting the mirrored healthy side bone reconstruction data and the mirrored diseased side bone reconstruction data to obtain a matching and fitting result; determining the position of a normal bone on the affected side of the long bone part based on the matching fitting result; comparing the position of the normal bone of the affected side with the reconstruction data of the bone of the affected side, and determining defect position information.

Optionally, constructing a bone defect prosthesis of the target object based on the defect site information, comprising: determining a bone type of the bone defect prosthesis based on the defect site information; based on the bone type, a bone defect prosthesis of the target object is constructed.

Optionally, determining the bone type of the bone defect prosthesis based on the defect site information, comprising: based on the bone morphology information and the bone lesion information in the defect site information, a bone type of the bone defect prosthesis is determined.

Optionally, determining the bone type of the bone defect prosthesis based on the bone morphology information and the bone lesion information in the defect site information, comprising one of: responsive to the bone morphology information being diaphyseal defects and not accumulating metaphyseal, determining the bone type as tubular; responsive to the bone morphology information being diaphyseal defects and accumulating metaphyseal, and the bone lesion information being the integrity of the intramedullary canal of the bone at the non-defective site and being devoid of other implants, determining that the bone type is tubular metaphyseal; responsive to bone morphology information being diaphyseal defects and accumulating metaphyseal bone and bone lesion information being incomplete medullary cavity of bone or other implant in the non-defective portion, determining a bone type as tubular side wing; determining the bone type as open responsive to the bone morphology information being either a global bone defect or a diaphyseal defect or an accumulated metaphyseal; in response to the bone morphology information being intact for the outer cortical bone and the bone lesion information being a mid-site defect of the intramedullary canal of the non-defective site bone, the bone type is determined to be solid filled.

Optionally, constructing a bone defect prosthesis based on the bone type, comprising: determining the diameter of an intramedullary pin corresponding to the reconstruction data of the affected side under the bone type; based on the intramedullary pin diameter, a bone defect prosthesis is constructed.

Optionally, component parameters of a fixation component are determined based on the defect site information, wherein the fixation component is used to fix the bone defect prosthesis to the target object.

Optionally, determining component parameters of the fixation component based on the defect site information, including at least one of: determining the type of a fixing plate in the fixing assembly under the bone width in the defect part information; the position and size of the nail hole in the fixation assembly is determined under the positional information in the defect site information.

According to another aspect of the embodiments of the present application, there is also provided a construction apparatus of a bone defect prosthesis, including: an acquisition unit configured to acquire a medical image of a target object; a first determination unit for determining long bone part affected side bone reconstruction data and healthy side bone reconstruction data in a target object based on the medical image; a second determination unit for determining defect site information in the long bone site based on the affected side bone reconstruction data and the healthy side bone reconstruction data; and a construction unit for constructing a bone defect prosthesis of the target object based on the defect site information.

According to another aspect of embodiments of the present application, there is also provided a computer-readable storage medium. The computer readable storage medium comprises a stored program, wherein the device in which the computer readable storage medium is located is controlled to execute the method for constructing the bone defect prosthesis according to the embodiment of the application when the program runs.

According to another aspect of the embodiments of the present application, there is also provided a processor. The processor is used for running a program, wherein the construction method of the bone defect prosthesis is executed when the program runs.

In the embodiment of the application, a medical image of a target object is acquired; determining affected side bone reconstruction data and healthy side bone reconstruction data of a long bone part in a target object based on the medical image; determining defect part information of the long bone part based on the affected side bone reconstruction data and the healthy side bone reconstruction data; based on the defect site information, a bone defect prosthesis of the target object is constructed. That is, the bone of the target object is reconstructed based on the medical image of the target object to obtain the affected side bone reconstruction data and the healthy side bone reconstruction data of the long bone part in the target object, defect position information is determined based on the affected side bone reconstruction data and the healthy side reconstruction data, and the bone defect prosthesis is constructed based on the defect position information, so that the technical effect of accurately constructing the bone defect prosthesis is realized, and the technical problem that the bone defect prosthesis cannot be accurately constructed is solved.

Drawings

The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiments of the application and together with the description serve to explain the application and do not constitute an undue limitation to the application. In the drawings:

FIG. 1 is a flow chart of a method of constructing a bone defect prosthesis according to an embodiment of the present application;

FIG. 2 is a schematic illustration of an implant according to the related art;

FIG. 3 is a schematic illustration of a bone defect treatment according to the related art;

FIG. 4 is a schematic view of a prosthetic structure according to the related art;

FIG. 5 is a flow chart of a method of preparing a bone defect prosthesis according to embodiments of the present application;

FIG. 6 is a schematic illustration of a patient side bone according to an embodiment of the present application;

FIG. 7 is a schematic illustration of a mirrored data fitting according to an embodiment of the present application;

FIG. 8 is a schematic view of a tubular bone defect prosthesis according to embodiments of the present application;

FIG. 9 is a schematic view of a tubular metaphyseal bone defect prosthesis according to an embodiment of the present application;

FIG. 10 is a schematic view of a tubular lateral abnormal bone defect prosthesis according to an embodiment of the present application;

FIG. 11 is a schematic illustration of an open bone defect prosthesis according to embodiments of the present application;

FIG. 12 is a schematic view of a filled bone defect prosthesis according to embodiments of the present application;

FIG. 13 is a schematic view of a narrow straight fixation plate according to an embodiment of the present application;

FIG. 14 is a schematic view of a wide straight fixation plate according to an embodiment of the present application;

FIG. 15 is a schematic view of a threaded installation according to an embodiment of the present application;

FIG. 16 is a schematic illustration of an anatomic fixation plate in accordance with an embodiment of the present application;

FIG. 17 is a schematic illustration of a screw installation according to an embodiment of the present application;

FIG. 18 is a schematic illustration of the overall structure of a prosthesis according to embodiments of the present application;

fig. 19 is a schematic view of a device for constructing a bone defect prosthesis according to an embodiment of the present application.

Detailed Description

In order to make the present application solution better understood by those skilled in the art, the following description will be made in detail and with reference to the accompanying drawings in the embodiments of the present application, it is apparent that the described embodiments are only some embodiments of the present application, not all embodiments. All other embodiments, which can be made by one of ordinary skill in the art based on the embodiments herein without making any inventive effort, shall fall within the scope of the present application.

It should be noted that the terms "first," "second," and the like in the description and claims of the present application and the above figures are used for distinguishing between similar objects and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used may be interchanged where appropriate such that embodiments of the present application described herein may be implemented in sequences other than those illustrated or otherwise described herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.

Example 1

In accordance with embodiments of the present application, there is provided an embodiment of a method of constructing a bone defect prosthesis, it being noted that the steps illustrated in the flowcharts of the figures may be performed in a computer system, such as a set of computer executable instructions, and that although a logical sequence is illustrated in the flowcharts, in some cases the steps illustrated or described may be performed in a different order than that illustrated herein.

Fig. 1 is a flow chart of a method of constructing a bone defect prosthesis, as shown in fig. 1, according to an embodiment of the present application, the method may include the steps of:

step S102, acquiring a medical image of a target object.

In the technical solution provided in step S102 in the present application, a medical image of a target object may be acquired. Wherein the target object may be a patient. The medical image may be an electronic computed tomography (Computed Tomography, abbreviated as CT) image, may also be referred to as a CT image or CT data image, and may include a medical image of an injured site and a medical image of a normal site.

Optionally, the body part of the target object may be photographed by means of X-ray, ultrasonic, etc. to obtain a medical image of the target object, and the injured part of the target object may be photographed to obtain a medical image of the injured part of the target object, which is to be noted herein only for example, and the method for obtaining the medical image is not specifically limited.

Step S104, based on the medical image, the affected side bone reconstruction data and the healthy side bone reconstruction data of the long bone part in the target object are determined.

In the technical scheme provided in the step S104, the medical image of the target object is obtained, and the medical image can be reconstructed in three dimensions to obtain the affected bone reconstruction data and the healthy bone reconstruction data of the long bone part of the target object. The long bone part may be long tube-shaped and distributed on bones of limbs, for example, may be tibia, femur, humerus, ulna, bones of limbs, etc., and the long bone part is not particularly limited herein. The bone reconstruction data of the affected side can be bone reconstruction data of the injured long bone part and can be three-dimensional data. The bone reconstruction data of the healthy side can be bone reconstruction data of a normal long bone part, can be three-dimensional data, for example, can be a three-dimensional stereo image. It should be noted that, the present invention is not limited to the specific form of the patient side bone reconstruction data and the healthy side bone reconstruction data.

Optionally, a medical image in an injured state and a medical image in an uninjured state of a long bone part in the target object can be acquired, and the medical image in the injured state and the medical image in the uninjured state can be subjected to three-dimensional reconstruction through a CT reconstruction bone model, so that the affected side bone reconstruction data and the healthy side bone reconstruction data of the long bone part in the target object are obtained.

For example, medical images of healthy side limbs and injured side limbs of a patient can be acquired, and the medical images can be three-dimensionally reconstructed through a CT reconstructed bone model to obtain patient side bone reconstruction data and healthy side bone reconstruction data of the patient.

Step S106, defect part information of the long bone part is determined based on the affected side bone reconstruction data and the healthy side bone reconstruction data.

In the above technical solution of step S106 of the present application, the defect site in the long bone site may be determined by comparing the reconstruction data of the affected bone with the reconstruction data of the healthy bone, so as to determine the defect site information of the long bone site. The defect site information may include information such as a position and a shape of a defect site of the defect bone reconstruction data, a thickness of the bone of the defect site, a lesion condition of the defect site, and the like, and may include a size of a defect range of the bone of the defect, which may be referred to as defect size information, which is only exemplified herein, without specific limitation to the defect site information.

Optionally, acquiring a medical image of a long bone part in an injured state and a medical image of a long bone part in the same position in an uninjured state, obtaining a medical image of an injured side and a medical image of an uninjured side, performing three-dimensional reconstruction on the medical image of the injured side to obtain bone reconstruction data of an affected side, and performing three-dimensional reconstruction on the medical image of the uninjured side to obtain bone reconstruction data of a healthy side. The affected side bone reconstruction data at this time is injured, and there is a defective portion. The defect site information of the long bone site can be determined by comparing the reconstruction data of the affected bone with the reconstruction data of the healthy bone.

For example, when a patient's right lower limb is injured, a medical image of the right lower limb and a medical image of the left lower limb may be acquired. Three-dimensional reconstruction is carried out on the medical image of the right lower limb to obtain reconstruction data of the bone on the affected side, and three-dimensional reconstruction is carried out on the medical image of the left lower limb to obtain reconstruction data of the bone on the healthy side. The reconstruction data of the affected side bones and the reconstruction data of the healthy side bones can be compared, so that the defect position information of the defect position of the right lower limb is determined.

Step S108, constructing a bone defect prosthesis of the target object based on the defect position information.

In the above-described step S108 of the present application, the bone defect prosthesis of the target object may be constructed based on the defect site information. Wherein, the bone defect prosthesis can be a prosthesis fixed at the defect site of the affected side.

In the related art, a bone defect prosthesis is usually fixed at a defect part of a patient by adopting a simple structural design, but the method needs to completely remove bone residues at metaphyseal, damages a natural joint surface with normal functions, easily causes larger wounds to the patient, causes a certain loss of the natural functions of the patient, and cannot be adapted according to the damage size of the patient, so that the technical problem that the bone defect prosthesis cannot be accurately constructed is caused. In the embodiment of the application, the affected side bone reconstruction data and the healthy side bone reconstruction data are generated based on the medical image, defect position information such as the position and the size of the damage is accurately determined based on the comparison result of the affected side bone reconstruction data and the healthy side bone reconstruction data, and the bone defect restoration is constructed based on the defect position information, so that the suitability of the constructed bone defect restoration to a target object is improved, and the technical effect of accurately constructing the bone defect restoration is achieved.

The application includes steps S102 to S108, obtaining a medical image of the target object; determining affected side bone reconstruction data and healthy side bone reconstruction data of a long bone part in a target object based on the medical image; determining defect part information of the long bone part based on the affected side bone reconstruction data and the healthy side bone reconstruction data; based on the defect site information, a bone defect prosthesis of the target object is constructed. That is, the bone of the target object is reconstructed based on the medical image of the target object to obtain the affected side bone reconstruction data and the healthy side bone reconstruction data of the long bone part in the target object, defect position information is determined based on the affected side bone reconstruction data and the healthy side reconstruction data, and the bone defect prosthesis is constructed based on the defect position information, so that the technical effect of accurately constructing the bone defect prosthesis is realized, and the technical problem that the bone defect prosthesis cannot be accurately constructed is solved.

The above-described method of this embodiment is further described below.

As an optional embodiment, step S106, determining defect site information of the long bone site based on the affected side bone reconstruction data and the healthy side bone reconstruction data, includes: mirror image processing is carried out on the bone reconstruction data of the healthy side; and determining defect position information based on the mirrored healthy side bone reconstruction data and the affected side bone reconstruction data.

In this embodiment, the reconstruction data of the healthy side bone may be mirrored, and the mirrored reconstruction data of the healthy side bone may be compared with the reconstruction data of the diseased side bone, thereby determining defect site information.

Optionally, the healthy-side bone reconstruction data and the affected-side bone reconstruction data are generally obtained by constructing medical images on the left and right sides of the long bone portion, so that mirror image processing can be performed on the healthy-side bone reconstruction data, so that similarity between the healthy-side bone reconstruction data and the affected-side bone reconstruction data can be improved, and healthy-side bone reconstruction data of the affected-side bone reconstruction data under normal conditions can be obtained. In order to accurately determine defect site information, mirrored healthy-side bone reconstruction data may be compared with diseased-side bone reconstruction data, so that the defect site information may be accurately determined.

As an optional embodiment, step S106, determining defect site information of the long bone site based on the mirrored healthy-side bone reconstruction data and the diseased-side bone reconstruction data, includes: matching and fitting the mirrored healthy side bone reconstruction data and the mirrored diseased side bone reconstruction data to obtain a matching and fitting result; determining the position of a normal bone on the affected side of the long bone part based on the matching fitting result; comparing the position of the normal bone of the affected side with the reconstruction data of the bone of the affected side, and determining defect position information.

In this embodiment, the mirrored healthy-side bone reconstruction data and the diseased-side bone reconstruction data may be subjected to matching fitting to obtain a matching fitting result, the position of the diseased-side normal bone of the long bone portion may be determined based on the matching fitting result, and the information of the damaged portion may be determined by comparing the position of the diseased-side normal bone with the diseased-side bone reconstruction data. The matching fitting result may include a portion where the reconstruction data of the affected bone coincides with the mirrored reconstruction data of the healthy bone, and a bone portion where the reconstruction data of the affected bone is missing, which may be a result of a three-dimensional image, and may be displayed in a three-dimensional image, a chinese character, or a number, etc., which is only given by way of example, and the representation form and the content of the matching fitting result are not particularly limited.

Optionally, the software may be used to perform mirror image processing on the bone reconstruction data of the healthy side, and the mirror image processed bone reconstruction data of the healthy side and the bone reconstruction data of the diseased side are matched and fitted to obtain a matching and fitting result, and the relative position of the residual bone of the diseased side may be determined based on the matching and fitting result, so that the size of the defect range of the bone of the diseased side may be determined, and the defect length of the prosthesis may be determined based on the determined size of the defect range of the bone of the diseased side. Wherein the overall shape and the size of the prosthesis are slightly smaller than or equal to the outer diameter of the filling material occupying the bone defect part

As an alternative embodiment, step S108, constructing a bone defect prosthesis of the target object based on the defect site information, includes: determining a bone type of the bone defect prosthesis based on the defect site information; based on the bone type, a bone defect prosthesis of the target object is constructed.

In this embodiment, the bone type of the bone defect prosthesis may be determined based on the defect site information; based on the bone type, a bone defect prosthesis of the target object is constructed. The bone types may include, among others: tubular, tubular metaphyseal, tubular side airfoil, filling, open, etc.

Optionally, the defect site information is different, and the bone type selected by the bone defect prosthesis is also different, so that the matching condition of the bone defect prosthesis and the target object can be improved. The bone type of the bone defect prosthesis can be determined according to the defect position information, and based on the bone type, the bone defect prosthesis more suitable for the target object can be constructed.

As an alternative embodiment, determining the bone type of the bone defect prosthesis based on the defect site information, comprises: based on the bone morphology information and the bone lesion information in the defect site information, a bone type of the bone defect prosthesis is determined.

In this embodiment, the bone type of the bone defect prosthesis may be determined based on the bone morphology information and the bone lesion information in the bone defect site information. The bone morphology information may be, for example, a bone abrasion morphology, for example, a diaphyseal defect, and is not particularly limited. The bone lesion information may be a lesion condition of a bone, for example, may be a complete condition of a medullary cavity of the bone, etc., and the bone lesion information is not particularly limited herein.

As an alternative embodiment, the bone type of the bone defect prosthesis is determined based on bone morphology information and bone lesion information in the defect site information, comprising one of: responsive to the bone morphology information being diaphyseal defects and not accumulating metaphyseal, determining the bone type as tubular; responsive to the bone morphology information being diaphyseal defects and accumulating metaphyseal, and the bone lesion information being the integrity of the intramedullary canal of the bone at the non-defective site and being devoid of other implants, determining that the bone type is tubular metaphyseal; responsive to bone morphology information being diaphyseal defects and accumulating metaphyseal bone and bone lesion information being incomplete medullary cavity of bone or other implant in the non-defective portion, determining a bone type as tubular side wing; determining the bone type as open responsive to the bone morphology information being either a global bone defect or a diaphyseal defect or an accumulated metaphyseal; in response to the bone morphology information being intact for the outer cortical bone and the bone lesion information being a mid-site defect of the intramedullary canal of the non-defective site bone, the bone type is determined to be solid filled.

In this embodiment, bone morphology information and bone lesion information are determined. Responsive to the bone morphology information being diaphyseal defects and not accumulating metaphyseal, the bone type is determined to be tubular.

Alternatively, when the morphological information of the affected side bone defect is diaphyseal defect and metaphyseal is not accumulated, the bone type can be determined to be tubular in shape in cooperation with the intramedullary nail. That is, the bone defect prosthesis may be formed in a tubular shape, the tubular middle hole being vertically penetrated, and the outer shape of the tube being identical to the shape of the healthy side of the defect portion. The inner diameter dimension of the tube is referenced to the diameter of the intramedullary nail with which it is used. Wherein the intramedullary nail diameter is determined with reference to the intramedullary diameter of the non-defective portion.

In this embodiment, the bone type is determined to be tubular metaphyseal in response to the bone morphology information being diaphyseal defects and accumulating metaphyseal and the bone pathology information being the intramedullary canal of the bone at the non-defect site being intact and free of other endoprostheses.

Optionally, when the morphological information of the defect of the bone at the affected side is diaphysis defect and metaphyseal defect is accumulated, and the pathological information is that the bone marrow cavity at the non-defect part is complete and no other implantation space is occupied. The bone type may be determined to be tubular metaphyseal for fitting an intramedullary nail. That is, the bone defect prosthesis may be an anatomic hollow structure, with a central circular hole extending vertically therethrough, the diameter of the circular hole being in accordance with the configuration of the diameter design of the intramedullary nail used in cooperation. Wherein the intramedullary nail diameter is determined with reference to the intramedullary diameter of the non-defective portion.

In this embodiment, the bone type is determined to be tubular flanking in response to bone morphology information being diaphyseal defects and accumulating metaphyseal and bone pathology information being incomplete in the medullary cavity of the bone at the non-defective site or having other implants.

Alternatively, when the morphological information of the defect of the bone at the affected side is diaphysis defect and metaphyseal defect is accumulated, and the pathological information is that the bone marrow cavity of the non-defect part is incomplete or has other internal implantation occupation. The bone type can be determined as a single tubular lateral profile. That is, the bone defect prosthesis may be an anatomic monolithic structure provided with independently designed intramedullary fixation posts having diameters determined with reference to the diameter of the intramedullary canal at the non-defective site, and lengths according to the available intramedullary lengths thereof.

In this embodiment, the bone type is determined to be open responsive to the bone morphology information being a global bone defect or diaphyseal defect or an accumulated metaphyseal.

Alternatively, when the morphological information of the affected side bone defect is a global bone defect, diaphysis defect, or accumulated metaphyseal defect, it may be determined that the bone type is an open bone defect prosthesis fixed by screws. That is, the bone defect prosthesis can be designed as an anatomic opening, can be designed as a thin-wall opening porous tube, and the middle vacancy is generally taken from a fibula of a body and matched with a foreign bone for bone grafting filling fusion.

In this embodiment, the bone type is determined to be solid filled in response to the bone morphology information being fully preserved for lateral cortical bone and the bone lesion information being a mid-site defect of the intramedullary canal of the non-defective site bone.

Optionally, when the morphological information of the defect of the bone at the side is that the cortical bone at the outer side of the defect part is still completely reserved, the defect of the middle part of the marrow cavity is reserved. The bone type may be determined to be a bone defect prosthesis filled by screw fixation. That is, bone defect repair (prosthesis) can be designed according to the size and morphology of the defect, and filling of the defect inside the medullary cavity can be performed.

In the related art, the joint is an anatomical abnormal structure region, the whole implant structure is difficult to assemble into a defect region below the joint surface, and the structural defect of the trunk part needs stronger mechanical support to complete mechanical conduction, so that the problem that a proper prosthesis structure cannot be constructed still exists for bone defects involved in the joint surface and accompanied by metaphyseal, in the embodiment of the application, the bone type of the bone defect prosthesis is determined based on bone morphology information and bone lesion information in defect position information, and the bone defect prosthesis is determined based on the bone type, so that the technical effect of accurately constructing a proper prosthesis structure is achieved.

As an alternative embodiment, constructing a bone defect prosthesis based on bone type, comprises: determining the diameter of an intramedullary pin corresponding to the reconstruction data of the affected side under the bone type; based on the intramedullary pin diameter, a bone defect prosthesis is constructed.

In this embodiment, the diameter of the intramedullary pin corresponding to the patient side reconstruction data may be determined for the bone type, and based on the diameter of the intramedullary pin, a bone defect prosthesis may be constructed.

For example, when determining a bone defect prosthesis of which the bone type is tubular, the size of the medullary cavity of the tubular bone defect prosthesis may be further determined, so that the diameter of the intramedullary needle may be determined based on the size of the medullary cavity. The length of the intramedullary pin may be determined based on the diaphyseal length; the shape of the inner hole of the prosthesis can be determined according to the intramedullary pin, and the diameter of the inner hole can be +2-6 mm of the intramedullary pin; a plurality of small bulges (the height can be 2-3 mm) are added at the joint position with the bone, so that the anti-rotation capability of the prosthesis can be effectively enhanced.

For another example, when determining that the bone type is a tubular side-profiled bone defect prosthesis, the intramedullary rod diameter size may be determined based on the intramedullary rod size by further determining the intramedullary rod size of the tubular side-profiled bone defect prosthesis. The maximum length of the intramedullary pin can be 1 to 1.5 times of the diaphyseal defect length; the design of the flank fixing plates is added at the two end parts of the prosthesis, and the design of the flank fixing plates is in order to follow the design specification of the fixing plates. The prosthesis may be secured by screws to obtain stabilization of the prosthesis itself.

As an alternative example, when determining that the bone type is an open bone defect prosthesis, the outline of the prosthesis may be determined by the health side data, and the design form may be a thin-walled open tubular form; the two ends of the prosthesis are added with smaller screw fixing plate designs, the screw fixing plate designs follow temporary simple fixation, and internal fixation is reduced as a reference; the prosthesis obtains the initial self-stabilization of the prosthesis by screw fixation. The open bone defect prosthesis may be used in conjunction with autologous bone grafting or allogeneic bone grafting.

As another alternative example, when determining that the bone type is a filled bone defect prosthesis, the design form of the prosthesis may be determined as a solid filling form; the two ends of the prosthesis can be provided with the movable convex wings, the design of the smaller screw fixing holes is added, the design of the screw fixing holes can follow temporary simple fixation, and the internal fixation is reduced as a reference; the prosthesis is fixed through screw holes and convex wings to obtain the initial self-stabilization of the prosthesis.

As an alternative embodiment, component parameters of a fixation component are determined based on the defect site information, wherein the fixation component is used to fix the bone defect prosthesis to the target object.

In this embodiment, the bone defect prosthesis may be secured to the target object by a securing assembly. Component parameters of the fixation component may be determined based on the defect site information. The component parameters may be parameters such as size, shape, and position of the fixed component. The fixing component can be a fixing plate, a screw and the like. The type and type of securing components and component parameters are not particularly limited herein and the components used for securing are within the scope of the present application.

For example, the type and size of the selected fixation plate may be determined based on the location of the defect site and the thickness of the bone at the defect site in the defect site information.

As an alternative embodiment, the component parameters of the fixation component are determined based on the defect site information, including at least one of: determining the type of a fixing plate in the fixing assembly under the bone width in the defect part information; the position and size of the nail hole in the fixation assembly is determined under the positional information in the defect site information.

In this embodiment, the type of fixation plate in the fixation assembly may be determined at the bone width in the defect site information. The type of fixation plate may include a straight fixation plate, an anatomic fixation plate, etc. The straight type fixing plate may be classified into two types of narrow type and wide type according to the width of the plate.

Alternatively, the bone defect prosthesis may be secured by a fixation plate and screws. When the residual bone at the position to be fixed is narrower, the straight fixing plate can be selected as a narrow straight fixing plate; when the residual bone at the fixing position is required to be wider, the straight fixing plate can be selected to be wide.

Alternatively, the prosthesis may be fixed to the patient's residual bone (normal bone on the affected side) by screws. The screw hole on the fixing plate can be designed into a spherical surface, and the size of the screw hole is slightly larger than the diameter of the screw, so that an adjusting space of about + -10 degrees can be provided for the screw.

For example, when the prosthesis needs to be inserted into the medullary cavity, the osteotomy surface is defined by the cortical osteotomy surface, the included angle between the plane tangent to the narrow fixing plate and the plane tangent to the fixing plate can be 90 degrees, and the adjustable range of the screw direction is + -15 degrees; the included angle between the tangent planes of the wide fixing plate and the fixing plate can be 65 degrees, and the adjustable range of the screw direction is +/-15 degrees. When the residual cortical bone at the osteotomy face cannot form a plane, the angular range may be properly enlarged, but may not exceed 35 degrees.

Alternatively, the anatomic fixation plates may be divided into two forms, type I and type II, depending on the length of the plate. And when the residual bone at the fixing position is required to be wider and shorter, selecting the type I, and otherwise selecting the type II.

For example, the prosthesis may be fixed to the patient's residual bone by screws. Meanwhile, in view of being suitable for the actual installation position of the prosthesis in operation as far as possible, the nail hole on the fixing plate is designed to be spherical, and the size of the nail hole is slightly larger than the diameter of the screw, so that an adjustment space of +/-10 degrees is provided for the screw.

For another example, when the prosthesis needs to be inserted into the medullary cavity, the osteotomy surface is based on the cortical osteotomy surface, the plane included angle between the I-type fixing plate and the curved surface of the threaded hole can be 90 degrees, the included angle between the threaded hole and the central line of the fixing plate is 10 degrees, and the adjustable range of the screw direction is +/-15 degrees; the plane included angle of the II-type fixing plate tangent to the curved surface of the threaded hole can be 90 degrees, the included angle between the threaded hole and the central line of the fixing plate is 10 degrees, and the included angle between the threaded hole and the central line of the fixing plate is 5 degrees. When the prosthesis needs to be inserted into the medullary cavity, the osteotomy surface can be based on the cortical bone osteotomy surface, and when the residual cortical bone at the osteotomy site cannot form a plane, the angular range can be properly enlarged, but cannot exceed 35 degrees.

In this embodiment, the overall structure of the bone defect prosthesis is mainly a porous structure, and the bone contact surface is a porous structure, so that a large-area surface in-growth condition can be ensured, a large number of porous structures also ensure the weight reduction of the prosthesis, and meanwhile, in order to ensure the weight reduction and the strength and stability of the prosthesis, a solid structure is also designed in the prosthesis, thereby achieving the effect of improving the fixation of the bone defect prosthesis and a target object.

According to the embodiment, based on the medical image of the target object, the bone of the target object is reconstructed to obtain the affected side bone reconstruction data and the healthy side bone reconstruction data of the long bone part in the target object, the defect position information is determined based on the affected side bone reconstruction data and the healthy side reconstruction data, and the bone defect prosthesis is constructed based on the defect position information, so that the technical effect of accurately constructing the bone defect prosthesis is achieved, and the technical problem that the bone defect prosthesis cannot be accurately constructed is solved.

Example 2

The technical solutions of the examples of the present application are exemplified below in conjunction with preferred embodiments.

Currently, traumatic, osteomyelitis and bone neoplastic bone defects are not uncommon in clinic and have been a very concern for traumatic orthopedics. Bone defects caused by osteomyelitis, trauma, tumors, etc. are common and very troublesome clinical diseases, and in the existing treatment methods, long bone defects are usually repaired by using an integral implant, for example, fig. 2 is a schematic diagram of an implant according to the related art, and as shown in fig. 2, long bone defects can be repaired by using a fibula with a blood vessel of an artificial bone. Fig. 3 is a schematic illustration of a bone defect treatment according to the related art, as shown in fig. 3, typically using a conventional fixed structural design or a single structural design, which cannot be adapted to the patient's defect.

In the related art, for a major bone defect of a diaphyseal end of an extremity, a tumor prosthesis is generally adopted, fig. 4 is a schematic view of a prosthesis structure according to the related art, and as shown in fig. 4, the prosthesis is generally designed by adopting a simple structure and is fixed at a defect part of a patient in a hard fixing manner, but the method needs to completely remove bone residues of the diaphyseal end, damages a natural joint surface with normal functions, causes more trauma to the patient, causes a certain loss to the natural function of the patient, and cannot be adapted according to the damage size of the patient. In some cases, the tumor prosthesis also needs to be repaired, i.e. replaced, which can further destroy the original bone tissue and cause further injury to the patient.

For diaphyseal and diaphyseal defects close to the joint surface, sufficient bone grafting is required for achieving the purpose of retaining the joint, and the joint surface can be supported. The manufacturing structure matched with the joint shape can realize accurate joint structural support, but the joint is an anatomic abnormal structure area, the whole implant structure is difficult to assemble into a defect area below the joint surface, and the structural defect of the trunk part needs stronger mechanical support to complete mechanical conduction. By combining the above situations, there is no suitable prosthesis structure at present for bone defects involving joint surfaces and accompanied by metaphyseal, and there is still a technical problem that a bone defect prosthesis cannot be accurately constructed.

In order to solve the above problems, embodiments of the present application provide a bone segment defect prosthesis and a method for preparing the same, which reconstruct bones of a target object based on medical images of the target object to obtain diseased side bone reconstruction data and healthy side bone reconstruction data of a long bone portion in the target object, determine defect site information based on the diseased side bone reconstruction data and the healthy side reconstruction data, and construct the bone defect prosthesis based on the defect site information, thereby realizing the technical effects of accurately constructing the bone defect prosthesis and solving the technical problems that the bone defect prosthesis cannot be accurately constructed

The embodiments of the present application are further described below.

Fig. 5 is a flowchart of a method of preparing a bone defect prosthesis, as shown in fig. 5, according to embodiments of the present application, which may include the following steps.

In step S501, a medical image of a patient is acquired.

In this embodiment, medical images of the healthy side limb and the injured side limb of the patient may be acquired, wherein the medical images may be CT images.

Step S502, performing three-dimensional reconstruction on the medical image.

In this embodiment, the three-dimensional reconstruction of the medical image may be performed by CT reconstruction bone models, resulting in patient-side bone reconstruction data and healthy-side bone reconstruction data.

Fig. 6 is a schematic diagram of an affected bone according to an embodiment of the present application, and as shown in fig. 6, the affected bone reconstruction data and the healthy bone reconstruction data may be CT reconstruction of the entire long bone portion, for example, CT reconstruction of tibia, femur, humerus, ulna, etc.

Step S503, designing a bone defect prosthesis.

In this embodiment, the design of the bone defect prosthesis may be performed based on the affected side bone reconstruction data and the healthy side bone reconstruction data.

Optionally, fig. 7 is a schematic diagram of image data fitting according to an embodiment of the present application, as shown in fig. 7, the healthy side bone reconstruction data may be subjected to image processing by using software, the healthy side bone reconstruction data after image processing and the diseased side bone reconstruction data may be subjected to matching fitting, and the relative position of the residual bone on the diseased side may be determined based on the matching fitting result, so that the size of the defect range of the diseased side may be determined, and the defect length of the prosthesis may be determined based on the determined size of the defect range of the diseased side. Wherein, the overall shape and size of the prosthesis are required to be slightly smaller than or equal to the outer diameter of the filling material occupying the bone defect part.

In this embodiment, the bone type of the bone defect prosthesis may be determined based on the bone defect morphology information and lesion information of the affected side bone defect. The bone types of the bone defect prosthesis may include, among others: tubular, tubular metaphyseal, tubular side airfoil, filling, and open.

Alternatively, fig. 8 is a schematic view of a tubular bone defect prosthesis according to an embodiment of the present application, and as shown in fig. 8, when the morphological information of the affected bone defect is diaphyseal defect, without accumulating metaphyseal, the bone type can be determined to be tubular type matching the intramedullary nail. That is, the bone defect prosthesis may be formed in a tubular shape, the tubular middle hole being vertically penetrated, and the outer shape of the tube being identical to the shape of the healthy side of the defect portion. The inner diameter dimension of the tube is referenced to the diameter of the intramedullary nail with which it is used. Wherein the intramedullary nail diameter is determined with reference to the intramedullary diameter of the non-defective portion.

For example, the intramedullary rod diameter size may be determined based on the intramedullary rod diameter size. The length of the intramedullary pin may be determined based on the diaphyseal length; the shape of the inner hole of the prosthesis can be determined according to the intramedullary pin, and the diameter of the inner hole can be +2-6 mm of the intramedullary pin; a plurality of small bulges (the height can be 2-3 mm) are added at the joint position with the bone, so that the anti-rotation capability of the prosthesis can be effectively enhanced.

Optionally, fig. 9 is a schematic view of a tubular metaphyseal bone defect prosthesis according to an embodiment of the present application, as shown in fig. 9, when the morphology information of the affected side bone defect is diaphyseal defect and metaphyseal defect is accumulated, and the lesion information is that the bone marrow cavity of the non-defect part is complete and no other implant takes place. The bone type may be determined to be tubular metaphyseal for fitting an intramedullary nail. That is, the bone defect prosthesis may be an anatomic hollow structure, with a central circular hole extending vertically therethrough, the diameter of the circular hole being in accordance with the configuration of the diameter design of the intramedullary nail used in cooperation. Wherein the intramedullary nail diameter is determined with reference to the intramedullary diameter of the non-defective portion.

For example, the intramedullary pin diameter size may be further determined for the tubular bone defect prosthesis based on the intramedullary cavity size. The length of the intramedullary pin may be determined based on the diaphyseal length; the shape of the inner hole of the prosthesis can be designed according to the intramedullary pin, and the diameter of the inner hole can be +2-6 mm of the intramedullary pin; the prosthesis may be located near the metaphyseal end and the design of the flanking fixation plates may be increased, the design dimensions of the flanking fixation plates may follow the design specifications of the fixation plates.

Alternatively, fig. 10 is a schematic view of a tubular lateral abnormal bone defect prosthesis according to an embodiment of the present application, as shown in fig. 10, when the morphological information of the affected lateral bone defect is diaphyseal defect and metaphyseal defect is accumulated, and the pathological information is that the bone marrow cavity of the non-defect part is incomplete or has other implantation occupation. The bone type can be determined as a single tubular lateral profile. That is, the bone defect prosthesis may be an anatomic monolithic structure provided with independently designed intramedullary fixation posts having diameters determined with reference to the diameter of the intramedullary canal at the non-defective site, and lengths according to the available intramedullary lengths thereof.

For example, the intramedullary rod diameter size may be further determined for the tubular side-profile bone defect prosthesis based on the intramedullary rod diameter size. The maximum length of the intramedullary pin can be 1 to 1.5 times of the diaphyseal defect length; the design of the flank fixing plates is added at the two end parts of the prosthesis, and the design of the flank fixing plates is in order to follow the design specification of the fixing plates. The prosthesis may be secured by screws to obtain stabilization of the prosthesis itself.

Alternatively, fig. 11 is a schematic view of an open bone defect prosthesis according to an embodiment of the present application, and as shown in fig. 11, when the morphological information of the affected side bone defect is a total bone defect, diaphyseal defect, or accumulated metaphyseal defect, it may be determined that the bone type is an open bone defect prosthesis fixed by screws. That is, the bone defect prosthesis can be designed as an anatomic opening, can be designed as a thin-wall opening porous tube, and the middle vacancy is generally taken from a fibula of a body and matched with a foreign bone for bone grafting filling fusion.

For example, the outline of the prosthesis can be determined by the health side data, and the design form can be a thin-wall opening tubular form; the two ends of the prosthesis are added with smaller screw fixing plate designs, the screw fixing plate designs follow temporary simple fixation, and internal fixation is reduced as a reference; the prosthesis obtains the initial self-stabilization of the prosthesis by screw fixation. The open bone defect prosthesis may be used in conjunction with autologous bone grafting or allogeneic bone grafting.

Alternatively, fig. 12 is a schematic view of a filled bone defect prosthesis according to an embodiment of the present application, as shown in fig. 12, when the morphological information of the affected bone defect is that cortical bone outside the defect site remains intact, and the middle part of the medullary cavity is defective. The bone type may be determined to be a bone defect prosthesis filled by screw fixation. That is, bone defect repair (prosthesis) can be designed according to the size and morphology of the defect, and filling of the defect inside the medullary cavity can be performed.

For example, by determining the design pattern of the prosthesis, the design may be in the form of a solid filling pattern; the two ends of the prosthesis can be provided with the movable convex wings, the design of the smaller screw fixing holes is added, the design of the screw fixing holes can follow temporary simple fixation, and the internal fixation is reduced as a reference; the prosthesis is fixed through screw holes and convex wings to obtain the initial self-stabilization of the prosthesis.

Step S504, determining a fixation plan based on the design principle of the bone defect prosthesis.

In this embodiment, the fixation schedule may be determined based on the design principles of the bone defect prosthesis.

In this embodiment, the bone defect prosthesis may be secured by a fixation plate and screws.

Alternatively, the straight fixing plate may be classified into two forms of a narrow type and a wide type according to the width of the plate.

Fig. 13 is a schematic view of a narrow straight fixation plate according to an embodiment of the present application, and as shown in fig. 13, the straight fixation plate may be selected to be narrow when the residual bone at the fixation site is narrow. Fig. 14 is a schematic view of a wide type of straight fixation plate according to an embodiment of the present application, as shown in fig. 14, the straight fixation plate may be selected to be wide when the residual bone at the fixation site is wide. Table 1 is a specification table of wide and narrow type straight fixing plates, and the wide and narrow type straight fixing plates are selected so as to meet the specifications of table 1.

Table 1 specification table of wide and narrow type straight fixing plate

Alternatively, fig. 15 is a schematic view of a threaded installation according to an embodiment of the present application, as shown in fig. 15, wherein the prosthesis may be secured to the patient's residual bone by screws. The screw hole on the fixing plate can be designed into a spherical surface, and the size of the screw hole is slightly larger than the diameter of the screw, so that an adjusting space of about + -10 degrees can be provided for the screw.

Table 2 is a table of the position and size of the nail hole in the three-dimensional space, as shown in Table 2, when the prosthesis needs to be inserted into the medullary cavity, the osteotomy surface is based on the cortical osteotomy surface, the included angle between the tangential planes of the narrow fixing plate and the fixing plate can be 90 degrees, and the adjustable range of the screw direction is +/-15 degrees; the included angle between the tangent planes of the wide fixing plate and the fixing plate can be 65 degrees, and the adjustable range of the screw direction is +/-15 degrees. When the residual cortical bone at the osteotomy face cannot form a plane, the angular range may be properly enlarged, but may not exceed 35 degrees.

TABLE 2 position of nail holes in three dimensional space

Alternatively, fig. 16 is a schematic view of an anatomic fixation plate according to an embodiment of the present application, which can be divided into two forms, type I and type II, according to the length of the plate, as shown in fig. 16. And when the residual bone at the fixing position is required to be wider and shorter, selecting the type I, and otherwise selecting the type II.

Table 3 is a table of the requirements for use of the anatomic type fixation plates, as shown in Table 3, the specifications for use of either type I or type II anatomic type fixation plates should meet the specifications of Table 3.

Table 3 table of usage requirements for anatomic fixation plates

Alternatively, fig. 17 is a schematic illustration of a screw installation according to an embodiment of the present application, as shown in fig. 17, by which the prosthesis may be secured to the patient's residual bone mass. Meanwhile, in view of being suitable for the actual installation position of the prosthesis in operation as far as possible, the nail hole on the fixing plate is designed to be spherical, and the size of the nail hole is slightly larger than the diameter of the screw, so that an adjustment space of +/-10 degrees is provided for the screw.

The table 4 is a position size table of a nail hole in an anatomic fixing plate in a three-dimensional space, when the prosthesis needs to be inserted into a medullary cavity part, the osteotomy surface is taken as a reference of a cortex osteotomy surface, the included angle between the plane tangent with the curved surface of the I-shaped fixing plate and the curved surface of the threaded hole can be 90 degrees, the included angle between the threaded hole and the central line of the fixing plate is 10 degrees, and the adjustable range of the screw direction is +/-15 degrees; the plane included angle of the II-type fixing plate tangent to the curved surface of the threaded hole can be 90 degrees, the included angle between the threaded hole and the central line of the fixing plate is 10 degrees, and the included angle between the threaded hole and the central line of the fixing plate is 5 degrees. When the prosthesis needs to be inserted into the medullary cavity, the osteotomy surface can be based on the cortical bone osteotomy surface, and when the residual cortical bone at the osteotomy site cannot form a plane, the angular range can be properly enlarged, but cannot exceed 35 degrees.

Table 4 table of position and size of nail holes in anatomic fixation plates in three dimensions

Optionally, fig. 18 is a schematic diagram of an overall structure of a prosthesis according to an embodiment of the present application, as shown in fig. 18, the overall structure of the prosthesis is mainly a porous structure, and the bone contact surface is a porous structure, so that a large area of surface ingrowth conditions can be ensured, a large number of porous structures also ensure the weight reduction of the prosthesis, meanwhile, in order to ensure the weight reduction and ensure the strength and stability of the prosthesis, a physical structure is also designed in the prosthesis, table 5 is a specification table of the prosthesis, as shown in table 5, the physical thickness of the prosthesis may be 2-5 mm, and according to the difference between the entity and the grid of the model of the prosthesis, the spatial position relationship between the entity and the grid and the design range of the plane dimension of the tangency between the 90 ° osteotomy surface and the curved surface of the screw hole located on the central line of the fixing plate are predetermined.

TABLE 5 Specification Table for prostheses

Step S505, the use condition of the bone defect prosthesis is acquired.

In this embodiment, the use of the bone defect prosthesis may be obtained, and the regimen may be further modified based on the use.

In the embodiment of the application, the bone of the target object is reconstructed based on the medical image of the target object to obtain the affected side bone reconstruction data and the healthy side bone reconstruction data of the long bone part in the target object, the defect position information is determined based on the affected side bone reconstruction data and the healthy side reconstruction data, and the bone defect prosthesis is constructed based on the defect position information, so that the technical effect of accurately constructing the bone defect prosthesis is realized, and the technical problem that the bone defect prosthesis cannot be accurately constructed is solved.

Example 3

According to an embodiment of the application, a device for constructing a bone defect prosthesis is also provided. The device for constructing a bone defect prosthesis can be used to perform the method for constructing a bone defect prosthesis in example 1.

Fig. 19 is a schematic view of a device for constructing a bone defect prosthesis according to an embodiment of the present application. As shown in fig. 19, the bone defect prosthesis construction device 1900 may include: an acquisition unit 1902, a first determination unit 1904, a second determination unit 1906, and a construction unit 1908.

An acquisition unit 1902 for acquiring a medical image of a target object.

A first determining unit 1904 is configured to determine, based on the medical image, long bone site affected side bone reconstruction data and healthy side bone reconstruction data in the target object.

A second determination unit 1906 for determining defect site information in the long bone site based on the affected side bone reconstruction data and the healthy side bone reconstruction data.

A construction unit 1908 for constructing a bone defect prosthesis of the target object based on the defect site information.

Optionally, the second determining unit 1906 further includes: the first processing module is used for carrying out mirror image processing on the reconstruction data of the bone on the healthy side; and determining defect position information based on the mirrored healthy side bone reconstruction data and the affected side bone reconstruction data.

Optionally, the second determining unit 1906 further includes: the second processing module is used for carrying out matching fitting on the mirrored healthy side bone reconstruction data and the affected side bone reconstruction data to obtain matching fitting results; determining the position of a normal bone on the affected side of the long bone part based on the matching fitting result; comparing the position of the normal bone of the affected side with the reconstruction data of the bone of the affected side, and determining defect position information.

Optionally, the building unit 1908 includes: a third processing module for determining a bone type of the bone defect prosthesis based on the defect site information; based on the bone type, a bone defect prosthesis of the target object is constructed.

Optionally, the third processing module includes: and the determination submodule is used for determining the bone type of the bone defect prosthesis based on the bone morphology information and the bone lesion information in the defect position information.

Optionally, the third processing module is further configured to determine that the bone type is tubular in response to the bone morphology information being a diaphyseal defect and not accumulating metaphyseal.

Optionally, the third processing module is further configured to determine the bone type as tubular metaphyseal in response to the bone morphology information being diaphyseal defects and accumulating metaphyseal, and the bone lesion information being the intramedullary canal of the non-defective bone being intact and free of other endoprostheses.

Optionally, the third processing module is further configured to determine the bone type as a tubular side wing in response to the bone morphology information being diaphyseal defects and accumulating metaphyseal, and the bone lesion information being incomplete in a medullary cavity of the bone at the non-defective site or having other internal implants.

Optionally, the third processing module is further configured to determine the bone type as open responsive to the bone morphology information being a global bone defect or a diaphyseal site defect or an accumulated metaphyseal.

Optionally, the third processing module is further configured to determine that the bone type is solid filled in response to the bone morphology information being fully preserved for the lateral cortical bone and the bone lesion information being a mid-site defect of the intramedullary canal of the bone at the non-defective site.

Optionally, the third processing module includes: a processing sub-module for determining an intramedullary pin diameter corresponding to the patient side reconstruction data under the bone type; based on the intramedullary pin diameter, a bone defect prosthesis is constructed.

Optionally, the apparatus further comprises: and a third determination unit that determines, based on the defect site information, component parameters of a fixation component for fixing the bone defect prosthesis to the target object.

Optionally, the third determining unit further includes: the determining module is used for determining the type of the fixing plate in the fixing assembly under the bone width in the defect part information; the position and size of the nail hole in the fixation assembly is determined under the positional information in the defect site information.

In the embodiment of the application, a medical image of a target object is acquired through an acquisition unit; determining, by a first determination unit, long bone part affected side bone reconstruction data and healthy side bone reconstruction data in a target object based on the medical image; determining, by the second determining unit, defect site information in the long bone site based on the affected side bone reconstruction data and the healthy side bone reconstruction data; the bone defect restoration of the target object is constructed based on the defect position information through the construction unit, so that the technical effect of accurately constructing the bone defect restoration is realized, and the technical problem that the bone defect restoration cannot be accurately constructed is solved.

Example 4

According to an embodiment of the present application, there is also provided a computer-readable storage medium including a stored program, wherein the program performs the method of constructing a bone defect prosthesis described in embodiment 1.

Example 5

According to an embodiment of the present application, there is also provided a processor for running a program, wherein the program, when run, performs the method of constructing a bone defect prosthesis described in embodiment 1.

The foregoing embodiment numbers of the present application are merely for describing, and do not represent advantages or disadvantages of the embodiments.

In the foregoing embodiments of the present application, the descriptions of the embodiments are emphasized, and for a portion of this disclosure that is not described in detail in this embodiment, reference is made to the related descriptions of other embodiments.

In the several embodiments provided in the present application, it should be understood that the disclosed technology content may be implemented in other manners. The above-described embodiments of the apparatus are merely exemplary, and the division of the units, for example, may be a logic function division, and may be implemented in another manner, for example, a plurality of units or components may be combined or may be integrated into another system, or some features may be omitted, or not performed. Alternatively, the coupling or direct coupling or communication connection shown or discussed with each other may be through some interfaces, units or modules, or may be in electrical or other forms.

The units described as separate units may or may not be physically separate, and units shown as units may or may not be physical units, may be located in one place, or may be distributed over multiple units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.

In addition, each functional unit in each embodiment of the present application may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit. The integrated units may be implemented in hardware or in software functional units.

The integrated units, if implemented in the form of software functional units and determined to be stand-alone products for sale or use, may be stored in a computer readable storage medium. Based on such understanding, the technical solution of the present application may be embodied in essence or a part contributing to the prior art or all or part of the technical solution in the form of a software product stored in a storage medium, including several instructions to cause a computer device (which may be a personal computer, a server or a network device, etc.) to perform all or part of the steps of the methods described in the embodiments of the present application. And the aforementioned storage medium includes: a U-disk, a Read-Only Memory (ROM), a random access Memory (RAM, random Access Memory), a removable hard disk, a magnetic disk, or an optical disk, or other various media capable of storing program codes.

The foregoing is merely a preferred embodiment of the present application and it should be noted that modifications and adaptations to those skilled in the art may be made without departing from the principles of the present application and are intended to be comprehended within the scope of the present application.

Claims

1. A method of constructing a bone defect prosthesis, comprising:

acquiring a medical image of a target object;

determining patient side bone reconstruction data and health side bone reconstruction data of a long bone portion in the target object based on the medical image;

determining defect site information for the long bone site based on the affected side bone reconstruction data and the healthy side bone reconstruction data;

and constructing the bone defect prosthesis of the target object based on the defect position information.

2. The method of claim 1, wherein determining the defect site information for the long bone site based on the affected side bone reconstruction data and the healthy side bone reconstruction data comprises:

mirror image processing is carried out on the bone reconstruction data of the healthy side;

and determining the defect position information based on the mirrored bone reconstruction data of the healthy side and the bone reconstruction data of the affected side.

3. The method of claim 2, wherein determining the defect site information for the long bone site based on the mirrored bone reconstruction data for the healthy side and the bone reconstruction data for the diseased side comprises:

matching and fitting the mirrored bone reconstruction data on the healthy side and the mirrored bone reconstruction data on the affected side to obtain a matching and fitting result;

determining the position of a normal bone on the affected side of the long bone part based on the matching fitting result;

comparing the position of the normal bone on the affected side with the reconstruction data of the bone on the affected side, and determining the defect position information.

4. The method of claim 1, wherein constructing the bone defect prosthesis of the target object based on the defect site information comprises:

determining a bone type of the bone defect prosthesis based on the defect site information;

constructing the bone defect prosthesis of the target object based on the bone type.

5. The method of claim 4, wherein determining the bone type of the bone defect prosthesis based on the defect site information comprises:

determining the bone type of the bone defect prosthesis based on bone morphology information and bone lesion information in the defect site information.

6. The method of claim 5, wherein determining the bone type of the bone defect prosthesis based on bone morphology information and bone lesion information in the defect site information comprises one of:

determining that the bone type is tubular in response to the bone morphology information being diaphyseal defects and not accumulating metaphyseal;

determining that the bone type is tubular metaphyseal in response to the bone morphology information being the diaphyseal defect and accumulating the metaphyseal, and the bone lesion information being the intact intramedullary canal of the non-defective bone and no other internal implants;

determining that the bone type is tubular flanking in response to the bone morphology information being the diaphyseal defect and accumulating the metaphyseal and the bone lesion information being the incomplete intramedullary canal or other internal implant of the non-defective portion bone;

determining the bone type as open responsive to the bone morphology information being a global bone defect or diaphyseal defect or an accumulated metaphyseal;

and determining that the bone type is solid filling type in response to the bone morphology information being completely reserved for outside cortical bone and the bone lesion information being a middle part defect of a medullary cavity of the bone at the non-defective part.

7. The method of claim 4, constructing the bone defect prosthesis based on the bone type, comprising:

determining an intramedullary pin diameter corresponding to the patient side reconstruction data under the bone type;

constructing the bone defect prosthesis based on the intramedullary pin diameter.

8. The method according to claim 1, wherein the method further comprises:

and determining component parameters of a fixing component based on the defect site information, wherein the fixing component is used for fixing the bone defect prosthesis on the target object.

9. The method of claim 8, wherein determining component parameters of the fixation component based on the defect site information comprises at least one of:

determining the type of the fixing plate in the fixing assembly under the bone width in the defect part information;

determining the position and size of the nail hole in the fixation assembly under the positional information in the defect site information.

10. A bone defect prosthesis construction apparatus, comprising:

an acquisition unit configured to acquire a medical image of a target object;

a first determination unit configured to determine, based on the medical image, long bone site affected side bone reconstruction data and healthy side bone reconstruction data in the target object;

A second determination unit configured to determine defect site information in the long bone site based on the affected side bone reconstruction data and the healthy side bone reconstruction data;

and a construction unit for constructing the bone defect prosthesis of the target object based on the defect site information.

11. A computer readable storage medium, characterized in that the computer readable storage medium comprises a stored program, wherein the program, when run, controls a device in which the computer readable storage medium is located to perform the method of any one of claims 1 to 9.