CN105303604A - Measuring method and system for single-side osteal damage of human body - Google Patents

Measuring method and system for single-side osteal damage of human body Download PDF

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CN105303604A
CN105303604A CN201510679632.XA CN201510679632A CN105303604A CN 105303604 A CN105303604 A CN 105303604A CN 201510679632 A CN201510679632 A CN 201510679632A CN 105303604 A CN105303604 A CN 105303604A
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bone
image
ipsilateral
cranial defect
dimensional model
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陈辉
朱以明
刘孟孟
张凤军
王宏安
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Institute of Software of CAS
Beijing Jishuitan Hospital
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Institute of Software of CAS
Beijing Jishuitan Hospital
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Abstract

The invention discloses a measuring method and system for single-side osteal damage of the human body. The corresponding osteal form at the uninjured side serves as a template, a 3D osteal CT image of the uninjured side is overturned to form a mirror image, and a 3D osteal CT image of the injured side is subtracted from the mirror image to obtain the accurate form of osteal defect at the injured side; and the parameters including the maximal length, width, depth and spatial position of the osteal defect position are measured to make comprehensive evaluation for the osteal defect of the injured side. Model reconstruction and 3D measurement are realized for single-side osteal defect of human body, the osteal defect can be evaluated accurately and comprehensively, and the method and system have great significance in effectively reducing the post-operation recurrence rate caused by the osteal defect.

Description

A kind of method and system for human body one-sided bones of extremities ilium damage measurement
Technical field
The invention belongs to computer-aided medical science field, be specifically related to a kind of method and system for human body one-sided bones of extremities ilium damage measurement.
Background technology
Many orthopaedics sufferers, because the many reasons such as wound, strain, tumour or autoimmunity class disease cause occurring that one-sided bones of extremities damages, part bony structures defect.In this case, often need to rebuild the bone structure of defect for recovering sufferer limb function.Now only have the accurate Morphological Features understanding defect bone structure, could planning surgery reconstruction mode effectively.
Due in this case, Ipsilateral bone structure often part damage or disappearance, only according to the exact form feature of borrowing the existing skeletal form of Ipsilateral to be difficult to know by inference bone before wound.At present, existing a large amount of anatomical researches for each position of human body confirm, the bone structure of the corresponding position of both limbs often mirror image each other, form is very approximate.In this case, side corresponding position bone structure can be good for and not damage front morphological template as Ipsilateral, calculate Ipsilateral bone structure lack part form.Because this template has the individualized feature of sufferer own, thus compared with this position bone general parameter or general aspect model for the method with reference to template carries out calculating the personal feature more meeting sufferer.
Summary of the invention
The present invention is directed to the problems referred to above, a kind of method and system for human body one-sided bones of extremities ilium damage measurement are proposed, utilize the corresponding skeletal form in strong side as template, by the three-dimensional CT image upset of corresponding for strong side bone for after mirror image, deduct Ipsilateral bone three-dimensional CT image, to obtain the exact form of Ipsilateral Cranial defect; Measure the parameter such as locus of the maximum length at Cranial defect place, width, the degree of depth, defect, realize the comprehensive assessment to Ipsilateral bone defect.
The technical solution used in the present invention is as follows:
For a method for human body one-sided bones of extremities ilium damage measurement, comprise the following steps:
1) medical image comprising same patient's bilateral same area target bone is split, extract strong side bony areas and Ipsilateral bony areas respectively.
2) respectively three-dimensional reconstruction is carried out to the strong side bone region image after segmentation and Ipsilateral bone region image, obtain strong side seam bone three-dimensional model and Ipsilateral bone three-dimensional model.
3) according to the position of key anatomical landmarks point and the Morphological Features of anatomical structure, analyze and the important anatomy structure identifying strong side seam bone three-dimensional model and Ipsilateral bone three-dimensional model, and with the important anatomy structure of mirror image each other for constraint, registration is carried out to strong side seam bone three-dimensional model and Ipsilateral bone three-dimensional model, obtains the registration matrix that corresponding Ipsilateral bone is registrated to the corresponding bone in strong side.
4) step 3 is utilized) the registration matrix that obtains, calculate the difference of strong side bone region image and Ipsilateral bone region image, obtain the Cranial defect faultage image of Ipsilateral bone.
5) three-dimensional reconstruction is carried out to Cranial defect faultage image, obtain Cranial defect three-dimensional model.
6) set up the three-dimensional system of coordinate of Cranial defect place bone, Cranial defect parameter is measured.
Further, Medical image segmentation algorithm is adopted to split medical image.
Preferably, step 1) adopt partitioning algorithm based on threshold value, and be aided with the method for finely tuning manually medical image is split, comprising:
1-1) based on the Iamge Segmentation of threshold value.A selected threshold range performs Threshold segmentation to same sequence medical image.
1-2) manually adjust single image segmentation result.Order browses the image after Threshold segmentation, for obviously there is the untight situation in bone edge, adopts manually picture point or setting-out mode to close bone edge; For the situation of the head of humerus with the adhesion of surrounding tissue phase, take manually to draw straight secant mode and phase adhesion part is separated.
Further, step 2) and 5) in adopt the three-dimensional reconstruction in computer graphics to carry out described three-dimensional modeling, as MC (MarchingCube, marching cube) algorithm etc.
Further, step 3) adopt the registration Algorithm in computer science to carry out three-dimensional model registration, as ICP (IterativeClosestPoint, iterative closest point) algorithm etc.
Above-mentioned registration process comprises: by calculating the Ipsilateral point cloud after rotating translation and the error distance between the some cloud of strong side, if error is greater than predetermined threshold value, continue the whole process of iteration, until error is less than predetermined threshold value, then thinks that registration is successful; Thereafter can finely tune registration by hand, as carried out being shifted or rotating.
Further, step 4) specifically comprise the following steps:
4-1) utilize step 3) the registration matrix that obtains, carries out three dimensions conversion to all voxels in the Ipsilateral bony areas after segmentation, the corresponding voxel in the bony areas of strong side, location;
4-2) according to the voxel corresponding relation in strong side and Ipsilateral bone three-dimensional model, calculate the difference of strong side seam bone image and Ipsilateral skeletal graph picture, obtain the Cranial defect faultage image of Ipsilateral bone;
4-3) utilization above walks the Cranial defect faultage image obtained, and rebuilds Cranial defect three-dimensional model, obtains the original form of Cranial defect.
Further, step 6) adopt the method for building up of three-dimensional system of coordinate in computer system to set up the three-dimensional system of coordinate of defect place bone, as with bone center of gravity for true origin, set up left-handed coordinate system, namely x-axis is to the right, and upwards, z-axis is forward for y-axis.
Further, step 6) in, described Cranial defect parameter comprises: Cranial defect maximum length, width, the degree of depth and the Cranial defect locus on healthy bone, select linear measurement instrument, click two end points of mode determination Cranial defect maximum length and width, the degree of depth with mouse, determine the numerical value of parameter; Preferred site survey instrument, with the innermost position of mouse-click mode determination Cranial defect, determines the three-dimensional coordinate of this position; Select angle measurement tool, measure direction residing for defect; Select volume measurement tool, measure the volume of Cranial defect.
Measure a system for the one-sided bones of extremities ilium damage of human body, comprise: display module, interactive module, Cranial defect processing module, data memory module, wherein:
Described Cranial defect processing module comprises again:
Iamge Segmentation submodule, for pending Image Segmentation Using, extracts strong side bony areas and Ipsilateral bony areas respectively;
Three-dimensional reconstruction submodule, for carrying out three-dimensional reconstruction to the strong side bone region image after segmentation and Ipsilateral bone region image and Cranial defect faultage image, obtains strong side seam bone three-dimensional model, Ipsilateral bone three-dimensional model and Cranial defect three-dimensional model respectively;
Registration submodule, for carrying out registration to strong side seam bone three-dimensional model, Ipsilateral bone three-dimensional model, obtains the registration matrix that corresponding Ipsilateral bone is registrated to the corresponding bone in strong side;
Cranial defect faultage image obtains submodule, for obtaining Cranial defect faultage image;
Anatomical structure measures submodule, for building the three-dimensional system of coordinate of defect place bone structure, provides the instrument needed for measurement;
Described interactive module, for detecting user's input, judges selected survey instrument, makes user and system carry out alternately, having participated in the parameter measurement of Cranial defect;
Described display module, for showing image segmentation result, is good for side seam bone three-dimensional model, Ipsilateral bone three-dimensional model and Cranial defect three-dimensional model, the three-dimensional system of coordinate of defect place bone structure.
Described data memory module comprises again:
Image data base, for the medical image of store patient, Iamge Segmentation data after Iamge Segmentation process, Cranial defect faultage image;
Three-dimensional modeling data storehouse, for storing strong side seam bone three-dimensional model, Ipsilateral bone three-dimensional model, Cranial defect three-dimensional model;
Anatomical structure database, for storing the important anatomy structure of human anatomy bone bone mark, and the anatomical structure mark that bilateral is corresponding.
Compared with prior art, the present invention has following advantage.
1. the present invention provides the method for the one-sided bones of extremities ilium damage of Measurement accuracy human body.
In the present invention, advantage is to have designed and Implemented a kind of method three dimensional CT technology being used for the one-sided bones of extremities ilium damage of human body.Utilize three dimensional CT technology can the feature of morphological feature of accurate description human bone ilium structure, the three-dimensional description of the locus on the bone structure of place to Cranial defect form and Cranial defect that the two-dimensional measurement method in the past that achieves cannot be accomplished, namely achieve to Cranial defect accurate, comprehensively measure.
2. method is with anatomy correlative study conclusion for theoretical foundation, can measure individual bone damage more personalized, accurately.
In the present invention, the measuring method proposed with in anatomical research about the bone structure of the corresponding position of both limbs often mirror image each other, the conclusion that form is similar to very much is foundation, do not damage front morphological template using strong side corresponding position bone structure as Ipsilateral, calculate Ipsilateral bone structure lack part form.Because this template has the individualized feature of sufferer own, thus compared with this position bone general parameter or general aspect model for the method with reference to template carries out calculating the personal feature more meeting sufferer.
3. present invention achieves the system that a kind of humerus skull defect based on three dimensional CT technology is measured.
The present invention adopts three dimensional CT technology, and use about the bone structure of the corresponding position of both limbs often mirror image each other in anatomy, the conclusion that form is similar to very much, in conjunction with computer vision technique, realizes the system of human body one-sided bones of extremities ilium damage measurement.
4., for specific clinical problem specialized designs software, have the advantages that to be simple and easy to, facilitate clinical practice.
System treatment scheme is relatively simple, is easy to operation.Due to real-time process, system can carry out Real-time Feedback to result, improves Consumer's Experience effect.
Accompanying drawing explanation
For the object described, and unrestriced object, foregoing and other aspect of the present invention makes an explanation with reference to the accompanying drawings in further detail, wherein:
Fig. 1 is the single cpu mode operation scenario schematic diagram of present system.
Fig. 2 is the remote mode operation scenario schematic diagram of present system.
Fig. 3 is the system framework figure that the present invention measures one-sided bones of extremities defect.
Fig. 4 is the method flow diagram that the present invention measures one-sided bones of extremities defect.
Fig. 5 (a) is the original head of humerus CT image of the present invention; Fig. 5 (b) is the image by obtaining after Iamge Segmentation; Fig. 5 (c) is three-dimension interaction process exploded view picture; Fig. 5 (d) is bilateral head of humerus registration design sketch; Fig. 5 (e) is Ipsilateral bone and Cranial defect schematic diagram; Fig. 5 (f) is Cranial defect image.
Embodiment
In order to make those skilled in the art better understand the present invention, below in conjunction with embodiment and accompanying drawing, the present invention being described in further detail, but not being construed as limiting the invention.
Fig. 1 and Fig. 2 is respectively single cpu mode operation scenario and the remote mode operation scenario of present system.This system process and analysis derive from the bilateral target bone image of same patient, for reducing Cranial defect form and parameter measurement.Wherein, medical imaging apparatus uses to pass through to obtain medical image to patient scan or imaging by user.The medical imaging modalities of different support dicom standards may be used for native system.Such as, medical image can be computed tomography method (CT) image and MRI image or any image from suitable image or data acquisition facility.
The view data obtained by medical imaging apparatus is supplied to computing machine or workstation to process by storage medium or accesses medical image data server.Computing machine or workstation provide user interface, and grant user browses medical image, operate these images and process these images with system mutual.User interface comprises display, and this display can be display screen, or protect image device, can be maybe to present medical image to user is visual and presents any other suitable display device of figure and content of text to user.During remote mode operation, system has the authority of accesses medical image data server.Medical image server can be the part of system.It also can be provided by foreign server supplier, as hospital information system.Although illustrate only stand-alone computer in Fig. 1, computing machine can be computing machine or the special purpose computer of any general object.It also can be embedded system, as the embedded system in the image-taking system comprising medical imaging instrument.
System also can comprise multiple peripherals, so that user can reappear or record the result of intermediate treatment or other Output rusults of system.Such as, exporting peripherals can be printer based on paper, can be used for producing hard copy report, for share with other doctors or for filing object.In addition, export peripherals and can comprise storage medium and medical image server, for changing or storing treated result.
Fig. 3 is the software system framework figure of measurement of the present invention one-sided bones of extremities ilium damage measurement.Comprise interface alternation layer, logical process layer and data resource layer.
Interface alternation layer is the interface of user and system interaction.Wherein interface comprises the layout of menu bar and tool bar and the Display designing of two dimensional image and three-dimensional model, comprise the graphical feedback of image segmentation result, the displaying of original three-dimensional model and target three-dimensional, the displaying of the three-dimensional system of coordinate of defect place bone.Interactive tool comprises mutual image processing toolbox when manually carrying out Iamge Segmentation, as clicked, fill and wiping; And mutual registration tools case during manual fine-tuning registration, as mobile and rotation.Survey instrument comprises the Survey Tool Kit of Cranial defect form, can measure, as survey instruments such as length, width, angle, volumes at faultage image and three-dimensional model space.Process record realizes the data record for the treatment of scheme, comprise CT picture of patient sequence, the parameter of interactive tool, intermediate processing results as image segmentation result, reconstruction three-dimensional model, Model registration obtains registration matrix and anatomical structure measuring unit obtains all measurement parameters.
At logical process layer, image segmentation unit completes pretreatment operation to strong side, Ipsilateral bone original CT image, extracts region of interest, after user interactions confirms, the segmentation image after process is carried out three-dimensional reconstruction.Registration unit carries out registration to strong side, Ipsilateral three-dimensional model, obtains the registration matrix that corresponding Ipsilateral bone structure is registrated to the corresponding bone in strong side.Defect and restore unit walks transformation matrix on utilizing, and carries out registration to strong side, the pretreated CT image of Ipsilateral, obtains the faultage image of Cranial defect part, rebuilds Cranial defect partial 3-D model; Anatomical structure measuring unit and interaction process unit, set up the coordinate system of defect place bone structure, and according to user-selected survey instrument, interactively completes the measurement of the parameter information such as position, length, width, angle to Cranial defect, and provides parameter feedback.
At data resource layer, comprise the medical science tomoscan image data of patient in image data base as CT image, Iamge Segmentation data after Iamge Segmentation process, Cranial defect part CT image; Three-dimensional modeling data storehouse is for depositing the three-dimensional model of strong side, Ipsilateral corresponding position bone, Cranial defect partial 3-D model; The important anatomy structure of the skeleton that anatomical structure database is deposited, and the anatomical structure mark that human body bilateral is corresponding.
Fig. 4 is the flow chart of steps that application such scheme carries out one-sided bones of extremities ilium damage measurement.It is divided into four-stage: pretreatment stage, Model registration stage, Cranial defect obtain stage, defect measuring phases.Illustrate with the example that is measured as of head of humerus Cranial defect.
Pretreatment stage, mainly completes function of image segmentation.In original head of humerus CT image (as Suo Shi Fig. 5 (a)), often have that the head of humerus is not obvious with the separatrix of shoulder blade, cancellous bone and surrounding tissue such as to obscure mutually at the situation in Cranial defect image, pass through Iamge Segmentation, solve above-described problem, extract the image only comprising head of humerus part, for subsequent step is prepared.Wherein, the image effect after segmentation is as shown in Fig. 5 (b), and position indicated by arrow is target head of humerus part.
Wherein image partition method, adopts the partitioning algorithm based on threshold value, and is aided with the method for finely tuning manually.
(1) based on the Iamge Segmentation of threshold value.A selected threshold range performs Threshold segmentation to same sequence C T image.
(2) manually single image segmentation result is adjusted.Order browses the image after Threshold segmentation, for obviously there is the untight situation in bone edge, adopts manual setting-out mode to close bone edge; For the situation of the head of humerus with the adhesion of surrounding tissue phase, take manually to draw straight secant mode and phase adhesion part is separated.
In the Model registration stage, mainly side is good for patient, Ipsilateral head of humerus three-dimensional model carries out registration.
(1) strong side, Ipsilateral head of humerus three-dimensional model is rebuild.Utilize the strong side after Iamge Segmentation, Ipsilateral head of humerus image respectively, adopt MarchingCube algorithm, rebuild and obtain strong side, Ipsilateral head of humerus three-dimensional model.
(2) registration is good for the three-dimensional model of side and the Ipsilateral head of humerus.Adopting ICP registration Algorithm, according to algorithm principle, by calculating the Ipsilateral point cloud after rotating translation and the error distance between the some cloud of strong side, if error is greater than predetermined threshold value, continuing the whole process of iteration, until error is less than predetermined threshold value, then think that registration is successful; Thereafter can finely tune registration by hand, as carried out being shifted or rotating; The transformation matrix obtained after confirming is supplied to Cranial defect and obtains stage use.Effect after bilateral head of humerus registration is as shown in Fig. 5 (d).
Cranial defect obtains the important stage that the stage is system.In this stage by using strong side head of humerus figure image subtraction Ipsilateral head of humerus image, to obtain the original form before Cranial defect part wears.To the execution step in Cranial defect acquisition stage be described in detail below:
(1) registration faultage image.This step object is patient's bilateral head of humerus image to carry out " mirror image alignment ".The coupling matrix Ipsilateral head of humerus being registrated to the strong side head of humerus utilizing the Model registration stage to obtain, carries out three dimensions conversion to all voxels in the Ipsilateral bony areas after segmentation, the corresponding voxel in the bony areas of strong side, location.
(2) according to the voxel corresponding relation in strong side and Ipsilateral skeleton model, calculate the difference of strong side seam bone image and Ipsilateral skeletal graph picture, obtain the faultage image of Ipsilateral skeletal bones defect.
(3) three-dimensional model of Cranial defect is rebuild.Utilization walks the Cranial defect faultage image obtained, rebuild Cranial defect three-dimensional model, obtain the original form of Cranial defect.Fig. 5 (f) illustrates the Cranial defect form after reconstruction.
Cranial defect measuring phases, mainly sets up the three-dimensional system of coordinate of the head of humerus in this stage, measure the maximum length of Cranial defect, width, the degree of depth, defect in the position of the head of humerus and defect major axis and humeral shaft major axis angle five parameters.
(1) head of humerus three-dimensional system of coordinate is set up.Set up head of humerus three-dimensional system of coordinate in the following way: adopt the method for building up of three-dimensional system of coordinate in computer system to set up head of humerus three-dimensional system of coordinate, as with head of humerus center of gravity for true origin, set up left-handed coordinate system, namely x-axis is to the right, and upwards, z-axis is forward for y-axis.
(2) Cranial defect parameter is measured.Select linear measurement instrument, click two end points of mode determination Cranial defect maximum length (and width, degree of depth) with mouse, determine the numerical value of parameter; Preferred site survey instrument, with the innermost position of mouse-click mode determination defect, determines the three-dimensional coordinate of this position; Select angle measurement tool, measure the angle of defect major axis and humeral shaft major axis; Select volume measurement tool, measure the volume of Cranial defect.
So far, the measurement whole process of whole Cranial defect three-dimensional configuration is completed.
In sum, The present invention gives the method and system of the one-sided bones of extremities ilium damage of a kind of Measurement accuracy.User adopts this method accurately can obtain the three-dimensional configuration of Cranial defect, greatly reduces workload and the processing time of measurement.Wherein, embodiment is only in order to illustrate technical scheme of the present invention but not to be limited; those of ordinary skill in the art can modify to technical scheme of the present invention or equivalent replacement; and not departing from the spirit and scope of the present invention, protection scope of the present invention should be as the criterion with described in claim.

Claims (10)

1., for a method for human body one-sided bones of extremities ilium damage measurement, comprise the following steps:
1) medical image comprising same patient's bilateral same area target bone is split, extract strong side bony areas and Ipsilateral bony areas respectively;
2) respectively three-dimensional reconstruction is carried out to the strong side bone region image after segmentation and Ipsilateral bone region image, obtain strong side seam bone three-dimensional model and Ipsilateral bone three-dimensional model;
3) according to the position of key anatomical landmarks point and the Morphological Features of anatomical structure, analyze and the important anatomy structure identifying strong side seam bone three-dimensional model and Ipsilateral bone three-dimensional model, and with the important anatomy structure of mirror image each other for constraint, registration is carried out to strong side seam bone three-dimensional model and Ipsilateral bone three-dimensional model, obtains the registration matrix that corresponding Ipsilateral bone is registrated to the corresponding bone in strong side;
4) step 3 is utilized) the registration matrix that obtains, calculate the difference of strong side bone region image and Ipsilateral bone region image, obtain the Cranial defect faultage image of Ipsilateral bone;
5) three-dimensional reconstruction is carried out to Cranial defect faultage image, obtain Cranial defect three-dimensional model;
6) set up the three-dimensional system of coordinate of Cranial defect place bone, Cranial defect parameter is measured.
2. as claimed in claim 1 for the method for human body one-sided bones of extremities ilium damage measurement, it is characterized in that, adopt Medical image segmentation algorithm to split medical image.
3., as claimed in claim 1 for the method for human body one-sided bones of extremities ilium damage measurement, it is characterized in that, step 1) adopt partitioning algorithm based on threshold value, and be aided with the method for finely tuning manually medical image is split, comprising:
1-1) a selected threshold range performs Threshold segmentation to same sequence medical image;
1-2) sequentially browsing the image after Threshold segmentation, for obviously there is the untight situation in bone edge, adopting manually picture point or setting-out mode to close bone edge; For the situation of the head of humerus with the adhesion of surrounding tissue phase, take manually to draw straight secant mode and phase adhesion part is separated.
4., as claimed in claim 1 for the method for human body one-sided bones of extremities ilium damage measurement, it is characterized in that, step 2) and 5) in three-dimensional reconstruction in employing computer graphics carry out described three-dimensional modeling.
5., as claimed in claim 1 for the method for human body one-sided bones of extremities ilium damage measurement, it is characterized in that, step 3) adopt the registration Algorithm in computer science to carry out three-dimensional model registration.
6. as claimed in claim 5 for the method for human body one-sided bones of extremities ilium damage measurement, it is characterized in that, described registration process comprises: by calculating the Ipsilateral point cloud after rotating translation and the error distance between the some cloud of strong side, if error is greater than predetermined threshold value, continue the whole process of iteration, until error is less than predetermined threshold value, then think that registration is successful.
7., as claimed in claim 1 for the method for human body one-sided bones of extremities ilium damage measurement, it is characterized in that, step 4) specifically comprise the following steps:
4-1) utilize step 3) the registration matrix that obtains, carries out three dimensions conversion to all voxels in the Ipsilateral bony areas after segmentation, the corresponding voxel in the bony areas of strong side, location;
4-2) according to the voxel corresponding relation in strong side and Ipsilateral bone three-dimensional model, calculate the difference of strong side seam bone image and Ipsilateral skeletal graph picture, obtain the Cranial defect faultage image of Ipsilateral bone;
4-3) utilization above walks the Cranial defect faultage image obtained, and rebuilds Cranial defect three-dimensional model, obtains the original form of Cranial defect.
8., as claimed in claim 1 for the method for human body one-sided bones of extremities ilium damage measurement, it is characterized in that, step 6) adopt the method for building up of three-dimensional system of coordinate in computer system to set up the three-dimensional system of coordinate of defect place bone.
9. as claimed in claim 1 for the method for human body one-sided bones of extremities ilium damage measurement, it is characterized in that, step 6) in, described Cranial defect parameter comprises: Cranial defect maximum length, width, the degree of depth and the Cranial defect locus on healthy bone; Select linear measurement instrument, click two end points of mode determination Cranial defect maximum length and width, the degree of depth with mouse, determine the numerical value of parameter; Preferred site survey instrument, with the innermost position of mouse-click mode determination Cranial defect, determines the three-dimensional coordinate of this position; Select angle measurement tool, measure direction residing for defect; Select volume measurement tool, measure the volume of Cranial defect.
10. measure a system for the one-sided bones of extremities ilium damage of human body, comprise: display module, interactive module, Cranial defect processing module, data memory module, wherein:
Described Cranial defect processing module comprises again:
Iamge Segmentation submodule, for pending Image Segmentation Using, extracts strong side bony areas and Ipsilateral bony areas respectively;
Three-dimensional reconstruction submodule, for carrying out three-dimensional reconstruction to the strong side bone region image after segmentation and Ipsilateral bone region image and Cranial defect faultage image, obtains strong side seam bone three-dimensional model, Ipsilateral bone three-dimensional model and Cranial defect three-dimensional model respectively;
Registration submodule, for carrying out registration to strong side seam bone three-dimensional model, Ipsilateral bone three-dimensional model, obtains the registration matrix that corresponding Ipsilateral bone is registrated to the corresponding bone in strong side;
Cranial defect faultage image obtains submodule, for obtaining Cranial defect faultage image;
Anatomical structure measures submodule, for building the three-dimensional system of coordinate of defect place bone structure, provides the instrument needed for measurement;
Described interactive module, for detecting user's input, judges selected survey instrument, makes user and system carry out alternately, having participated in the parameter measurement of Cranial defect;
Described display module, for showing image segmentation result, is good for side seam bone three-dimensional model, Ipsilateral bone three-dimensional model and Cranial defect three-dimensional model, the three-dimensional system of coordinate of defect place bone structure.
Described data memory module comprises again:
Image data base, for the medical image of store patient, Iamge Segmentation data after Iamge Segmentation process, Cranial defect faultage image;
Three-dimensional modeling data storehouse, for storing strong side seam bone three-dimensional model, Ipsilateral bone three-dimensional model, Cranial defect three-dimensional model;
Anatomical structure database, for storing the important anatomy structure of human anatomy bone bone mark, and the anatomical structure mark that bilateral is corresponding.
CN201510679632.XA 2015-10-19 2015-10-19 Measuring method and system for single-side osteal damage of human body Pending CN105303604A (en)

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CN107358608A (en) * 2017-08-23 2017-11-17 西安邮电大学 Bone tissue geometric state parameter auto-testing device and method based on image processing techniques
CN107358608B (en) * 2017-08-23 2023-07-21 西安邮电大学 Automatic bone tissue geometric parameter measuring device and method based on image processing technology
CN111226220B (en) * 2017-09-07 2023-06-20 港大科桥有限公司 Bone model, modeling process and system thereof
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CN107967678B (en) * 2017-09-18 2021-11-02 广州慧扬健康科技有限公司 Bone destruction degree feature extraction system
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CN108245288A (en) * 2018-03-26 2018-07-06 江苏天行增材制造科技有限公司 A kind of 3D printing prosthese for treating distal radius tumour and manufacturing method
CN110648329A (en) * 2019-03-29 2020-01-03 中国科学院深圳先进技术研究院 Target image extraction method, system and terminal equipment
CN110648329B (en) * 2019-03-29 2023-12-26 中国科学院深圳先进技术研究院 Target image extraction method, system and terminal equipment
JP7463510B2 (en) 2019-11-26 2024-04-08 ホウメディカ・オステオニクス・コーポレイション Preoperative planning and intraoperative guidance for orthopedic surgery in cases of bone fragmentation
CN110910379A (en) * 2019-11-29 2020-03-24 珠海大横琴科技发展有限公司 Incomplete detection method and device
CN110910379B (en) * 2019-11-29 2020-07-17 珠海大横琴科技发展有限公司 Incomplete detection method and device
CN112120789B (en) * 2020-09-08 2022-08-05 杭州三坛医疗科技有限公司 Broken bone reduction simulation method and broken bone reduction simulation device
CN112120789A (en) * 2020-09-08 2020-12-25 杭州三坛医疗科技有限公司 Broken bone reduction simulation method and broken bone reduction simulation device
CN112381922A (en) * 2020-10-27 2021-02-19 济南大学 Method, system and terminal for obtaining skeleton model of human skeleton missing part
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