CN116106529A

CN116106529A - Medical all-in-one machine

Info

Publication number: CN116106529A
Application number: CN202210940611.9A
Authority: CN
Inventors: 罗伟; 余波; 章铖皓; 车慧佳; 童明; 单立钢
Original assignee: Zhejiang Pushkang Biotechnology Co ltd
Current assignee: Zhejiang Pushkang Biotechnology Co ltd
Priority date: 2022-08-06
Filing date: 2022-08-06
Publication date: 2023-05-12

Abstract

The application discloses a medical all-in-one. The medical all-in-one machine comprises a machine body, a detection module, a sample/reagent module and a sample adding module. The machine body comprises a detection table and a rack arranged above the detection table; the detection modules are multiple, are arranged on the detection table and are used for detecting different detection items; the sample/reagent module is arranged on the detection platform for placing a sample and a reagent; the sample adding module is arranged on the rack and moves back and forth between the detection module and the sample/reagent module to suck and add samples and reagents. The medical all-in-one machine in the application can carry out multi-project detection, is high in detection efficiency, and can meet different use demands of medical staff.

Description

Medical all-in-one machine

Technical Field

The application relates to the technical field of medical equipment, in particular to a medical all-in-one machine.

Background

With the continuous popularization and application of the microfluidic technology in the medical field, a biochemical detector, a coagulation detector and a luminescence immunity detector which detect by using the microfluidic technology are generated.

However, the current biochemical detection instrument can only perform biochemical detection, the blood coagulation detection instrument can only perform blood coagulation detection, the light-emitting immunity detection instrument can only perform immunity detection, when a plurality of items of detection are required to be performed on a sample, the detection efficiency is low, and the use requirements of medical staff are difficult to meet.

Disclosure of Invention

The main aim of this application is to provide a medical all-in-one, this medical all-in-one is last not only can carry out the blood coagulation detection, also can carry out biochemical detection and immunodetection, and detection efficiency is high.

According to an aspect of an embodiment of the present application, there is provided a medical all-in-one machine including:

the machine body comprises a detection table and a rack arranged above the detection table;

the detection modules are arranged on the detection table and used for detecting different detection items;

a sample/reagent module disposed on the detection stage for placement of a sample and a reagent; and

and the sample adding module is arranged on the rack and moves back and forth between the detection module and the sample/reagent module so as to absorb and add samples and reagents.

Further, the detection module at least comprises a PMT detection module and an optical method detection module, wherein,

the PMT detection module is arranged on the detection table and used for performing immune detection;

the optical method detection module is arranged on the detection table and used for biochemical and/or coagulation detection.

Further, the PMT detection module and the optical detection module are disposed side by side behind the detection stage, and the sample/reagent module is disposed in front of the detection stage.

Further, the PMT detection module includes:

the first mounting frame is mounted on the detection table;

the first tray frame is rotatably arranged on the first mounting frame and is used for placing microfluidic discs; and

the PMT detection assembly is arranged at the bottom of the first mounting frame and positioned at the bottom of the first tray frame, and comprises a light-sealing unit and a PMT detection unit, and the light-sealing unit is arranged on the PMT detection unit in a lifting manner.

Further, the optical method detection module includes:

the second mounting frame is mounted on the detection table;

the second tray frame is rotatably arranged on the second mounting frame and is used for placing the microfluidic disc; and

the light source is arranged on the second mounting frame.

Further, the sampling module includes:

the first guide rail assembly is arranged on the rack and is positioned above the detection table;

the first lifting assembly is arranged on the first guide rail assembly and can move along the first guide rail assembly; and

the sample adding assembly is arranged on the first lifting assembly to absorb and add samples and reagents.

Further, the first guide rail assembly comprises a first guide rail mechanism, and the first guide rail mechanism is arranged on the rack and is positioned above the detection table;

the first lifting assembly comprises a first lifting mechanism which is arranged on the first guide rail mechanism and can move along the first guide rail mechanism;

the sample application assembly comprises a first sample application needle which extends along the height direction of the frame so as to puncture the bottle stopper of the sample bottle and suck and apply the sample.

Further, the first guide rail assembly further comprises a second guide rail mechanism, and the second guide rail mechanism is arranged on the rack and is positioned above the detection table;

the first lifting assembly further comprises a second lifting mechanism, and the second lifting mechanism is arranged on the second guide rail mechanism and can move along the second guide rail mechanism;

the loading assembly further includes a second loading needle extending along the height direction of the frame for performing aspiration and loading of reagents.

Further, the medical all-in-one machine further includes:

the disc storage module comprises a new disc storage bin and a waste disc storage bin; and

and the feeding and discharging module is arranged on the frame, and reciprocates among the PMT detection module, the optical method detection module, the new disc storage bin and the waste disc storage bin to feed and discharge the microfluidic disc.

Further, the loading and unloading module comprises:

the second guide rail assembly is arranged on the rack and is positioned above the detection table;

the second lifting assembly is arranged on the second guide rail assembly and moves along the second guide rail assembly; and

and the clamping jaw assembly is arranged on the second lifting assembly and used for clamping or releasing the microfluidic disc.

Compared with the prior art, the technical scheme of the application has at least the following technical effects:

in actual operation, according to the items to be detected, the microfluidic disc is placed on the corresponding detection module, then the sample/reagent module is used for filling the reagent or the sample placed on the sample/reagent module into the microfluidic disc, and after the sample and the reagent react completely in the microfluidic disc, the sample can be detected through the detection function of the detection module.

Because be provided with a plurality of detection module on the detection platform in this application, and foretell a plurality of detection module can be used for detecting different detection items, that is to say, medical all-in-one in this application can carry out multi-item detection, and detection efficiency is high, can satisfy medical personnel's different user demands.

Drawings

The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiments of the application and together with the description serve to explain the application and do not constitute an undue limitation to the application. In the drawings:

fig. 1 is a schematic structural view of a medical integrated machine (with a housing removed) according to an embodiment of the present application;

FIG. 2 is a top view of FIG. 1;

fig. 3 is a schematic structural diagram of a PMT detection module disclosed in an embodiment of the present application;

fig. 4 is a front view of a PMT detection module disclosed in an embodiment of the present application;

FIG. 5 is a cross-sectional view B-B of FIG. 4;

FIG. 6 is a schematic structural diagram of an optical detection module according to an embodiment of the present disclosure;

FIG. 7 is a front view of an optical detection module disclosed in an embodiment of the present application;

FIG. 8 is a cross-sectional view A-A of FIG. 7;

fig. 9 is a schematic structural diagram of a loading and unloading module and a disc storage module according to an embodiment of the present disclosure.

Wherein the above figures include the following reference numerals:

10. a body; 11. a detection table; 12. a frame; 20. a detection module; 21. a PMT detection module; 211. a first mounting frame; 212. a first tray rack; 213. a PMT detection assembly; 2131. PMT detection unit; 2132. a light-sealing unit; 214. a first cover; 2141. a sample adding hole; 2142. an electromagnetic valve; 215. a first motor; 22. an optical method detection module; 221. a second mounting frame; 222. a second tray rack; 223. a light source; 224. a slide rail; 225. a second cover; 2251. a sample adding through hole; 226. a second motor; 30. a sample/reagent module; 40. a sample adding module; 42. a first lifting assembly; 421. a first lifting mechanism; 422. a second lifting mechanism; 43. a sample application assembly; 431. a first sample addition needle; 432. a second sample addition needle; 50. a disk storage module; 51. a new disc storage bin; 52. a waste disc storage bin; 60. feeding and discharging modules; 61. a second rail assembly; 62. a second lifting assembly; 63. a jaw assembly; 70. microfluidic discs.

Detailed Description

It should be noted that, in the case of no conflict, the embodiments and features in the embodiments may be combined with each other. The present application will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments in accordance with the present application. As used herein, the singular is also intended to include the plural unless the context clearly indicates otherwise, and furthermore, it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.

The relative arrangement of the components and steps, numerical expressions and numerical values set forth in these embodiments do not limit the scope of the present application unless it is specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective parts shown in the drawings are not drawn in actual scale for convenience of description. Techniques, methods, and apparatus known to one of ordinary skill in the relevant art may not be discussed in detail, but should be considered part of the authorization specification where appropriate. In all examples shown and discussed herein, any specific values should be construed as merely illustrative, and not a limitation. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further discussion thereof is necessary in subsequent figures.

Referring to fig. 1, 2 and 9, according to an embodiment of the present application, a medical integrated machine is provided, which includes a machine body 10, a detection module 20, a sample/reagent module 30 and a loading module 40.

Wherein the machine body 10 comprises a detection table 11 and a rack 12 arranged above the detection table 11; the detection modules 20 are multiple, the multiple detection modules 20 are all arranged on the detection table 11, and the multiple detection modules 20 are used for detecting different detection items; a sample/reagent module 30 is provided on the detection stage 11 for placing a sample and a reagent; the sample application module 40 is disposed on the housing 12 and reciprocates between the detection module 20 and the sample/reagent module 30 for aspirating and applying samples, such as blood samples, urine samples, and the like.

In actual operation, according to the items to be detected, the microfluidic disc 70 is placed on the corresponding detection module 20, then the sample loading module 40 is used to load the reagent or sample placed on the sample/reagent module 30 into the microfluidic disc 70, and after the sample and the reagent react completely in the microfluidic disc 70, the sample can be detected by the detection action of the detection module 20.

Because the detection table 11 in this embodiment is provided with a plurality of detection modules 20, and the plurality of detection modules 20 can be used for detecting different detection items, that is, the medical all-in-one machine in this embodiment can detect multiple items, has high detection efficiency, and can meet different use demands of medical staff.

Further, the machine body 10 in this embodiment is generally rectangular, and a housing (not shown) is disposed outside the machine body 10, and the housing is disposed on the rack 12 in a reversible manner, so that the housing can be covered on the outer periphery of the detection table 11 and the rack 12 during actual use, and interference of the external environment on the detection module 20, the sample/reagent module 30 and the sample application module 40 can be prevented.

Referring to fig. 1 to 5, the detection module 20 in the present embodiment includes at least a PMT detection module 21 and an optical detection module 22. Wherein, PMT detection module 21 is disposed on detection stage 11 for performing an immunoassay; an optical detection module 22 is provided on the detection stage 11 for performing biochemical and/or coagulation detection. That is, the medical all-in-one machine in this embodiment not only can perform coagulation detection, but also can perform biochemical detection and immunodetection, and can satisfy different use demands of medical staff. Of course, in other embodiments of the present application, the detection module 20 may also include a molecular detection module, which is within the scope of the present application as long as other modifications are contemplated by the present application.

In the present embodiment, the PMT detection module 21 and the optical detection module 22 are disposed in parallel behind the detection stage 11, and the sample/reagent module 30 is disposed in front of the detection stage 11. It should be understood that the front and back in this embodiment refer to the front and back of the machine body 10 when in use, that is, the front side facing the medical staff and the back side facing away from the medical staff. In the present application, the PMT detection module 21 and the optical method detection module 22 are arranged in parallel behind the detection table 11, and the sample/reagent module 30 is arranged in front of the detection table 11, so that the space on the detection table 11 can be reasonably utilized, the miniaturized design of the medical integrated machine can be conveniently realized, and the medical integrated machine can be conveniently carried.

Further, the PMT detection module 21 in this embodiment includes a first mounting bracket 211, a first tray bracket 212, and a PMT detection assembly 213. Wherein the first mounting frame 211 is mounted on the detection table 11; the first tray rack 212 is rotatably disposed on the first mounting rack 211, and the first tray rack 212 is used for placing the microfluidic disc 70; the PMT detection assembly 213 is disposed on the first mounting frame 211 and is disposed at the bottom of the first tray frame 212, and the PMT detection assembly 213 includes a light blocking unit 2132 and a PMT detection unit 2131, wherein the light blocking unit 2132 is disposed on the PMT detection unit 2131 in a liftable manner. Optionally, the light sealing unit 2132 includes a lifting cylinder and an elastic sealing ring, where one end of the elastic light sealing ring is fixedly connected to the PMT detecting unit 2131, and when the lifting cylinder lifts, the elastic sealing ring can be driven to lift. In actual operation, after the reagent and the sample in the microfluidic disc 70 react well, the lifting cylinder is controlled to rise, the elastic sealing ring abuts against the detection hole at the bottom of the microfluidic disc 70, at this time, the elastic sealing ring can seal the gap between the PMT detection unit 2131 and the microfluidic disc 70, so that external light is prevented from entering the detection channel of the PMT detection unit 2131, and the detection precision of the PMT detection assembly 213 can be improved. PMT detection assembly 213 includes a photomultiplier tube (PMT), which is a photon counter by which the reacted sample is valued, and then the value is transmitted to the controller of the medical all-in-one machine for processing, ultimately effecting immunodetection.

Further, the PMT detection module 21 in this embodiment further includes a first cover 214 and a first motor 215, where the first cover 214 is disposed on the first mounting frame 211, and the first cover 214 has a sealing position for capping the first tray frame 212 and an avoidance position for avoiding the first tray frame 212. When the first cover 214 is in the cover position, the microfluidic disc 70 placed in the first tray 212 can be covered, so that the influence of the external environment on the detection process of the sample is avoided; when the second cover 225 is in the avoidance position, the microfluidic disk 70 is easy to be disassembled and assembled. Optionally, structures such as a sample adding hole 2141 and an electromagnetic valve 2142 are disposed on the first cover 214, and by the action of the sample adding hole 2141, reagent and sample are conveniently added, a sealing member, such as a sealing block, is disposed at the end of the electromagnetic valve 2142, and the electromagnetic valve 2142 moves to drive the sealing member to seal the sample adding hole 2141, so that the PMT detection module 21 is in a relatively sealed environment, and adverse effects of external light on the PMT detection module 21 detection process are avoided.

Referring to fig. 1, 2, and 6 to 8, the optical method detection module 22 in the present embodiment includes a second mounting frame 221, a second tray frame 222, and a light source 223. Wherein the second mounting frame 221 is mounted on the detection stage 11; the second tray 222 is rotatably disposed on the second mounting frame 221, and the second tray 222 is used for placing the microfluidic disc 70; a light source 223 is provided to the second mount 221 for illuminating the sample within the microfluidic disc 70. A second motor 226 is provided at the bottom of the second tray frame 222, and the second motor 226 is connected to the second tray frame 222 for driving the second tray frame 222 to rotate. When in use, the second motor 226 rotates according to the control program set on the medical integrated machine, so as to drive the microfluidic disc 70 placed on the second tray frame 222 to rotate, when the microfluidic disc 70 rotates, the sample in the microfluidic disc 70 can be separated or the reagent and the sample react, after the reagent and the sample react completely, the sample on the microfluidic disc 70 is irradiated by the light source 223 under the action of the light source 223 on the second mounting frame 221, and after that, the optical signal of the sample irradiated by the light source is collected by the light source by adopting the light cell and other sampling elements, and the sample is transmitted to the controller of the medical integrated machine for analysis and treatment, so that the biochemical or blood coagulation detection of the sample can be realized.

Optionally, the light source 223 in this embodiment includes at least four LED lamps with wavelengths of 405nm, 575nm, 660nm and 800nm, where the LED lamps have strong illumination intensity and low energy consumption, and even if used for a long time, the LED lamps will not be blackened, so that the service life of the medical integrated machine can be prolonged. In the embodiment, the wavelength of the LED lamp is set to 405nm, 575nm, 660nm and 800nm, so that the use requirements of general biochemical and blood coagulation detection items can be met. Of course, in other embodiments of the present application, four or more LED lamps may be provided, and any other modifications under the concept of the present application are within the scope of the present application.

Further, the optical method detection module 22 in this embodiment further includes a sliding rail 224 and a second cover 225, where the sliding rail 224 is disposed on the second mounting frame 221, and the second cover 225 is movably mounted on the sliding rail 224, and the second cover 225 has a sealing position for covering the second tray frame 222 and an avoidance position for avoiding the second tray frame 222. When the second cover 225 is in the cover position, the microfluidic disc 70 placed in the second tray 222 can be covered, so as to avoid the influence of the external environment on the detection process of the sample; when the second cover 225 is in the avoidance position, the microfluidic disk 70 is easy to be disassembled and assembled. Optionally, the second cover 225 is provided with a sample-adding through hole 2251, so as to facilitate reagent and sample filling.

Referring to fig. 1, 2 and 9, the loading module 40 includes a first rail assembly (not shown), a first lift assembly 42 and a loading assembly 43. The first guide rail component is arranged on the frame 12 and is positioned above the detection table 11; the first lifting assembly 42 is disposed on the first rail assembly and is movable along the first rail mechanism; the sample adding component 43 is disposed on the first lifting component 42 to suck and add the sample and the reagent.

Specifically, the first rail assembly includes a first rail mechanism provided on the frame 12 above the detection table 11; the first lifting assembly 42 comprises a first lifting mechanism 421, and the first lifting mechanism 421 is arranged on the first guide rail mechanism and can move along the first guide rail mechanism; the loading assembly 43 includes a first loading needle 431, and the first loading needle 431 extends along the height of the frame 12 to pierce the stopper of the sample vial and aspirate and load the sample.

Further, the first guide rail assembly further comprises a second guide rail mechanism, which is arranged on the frame 12 and is positioned above the detection table 11; the first lifting assembly 42 further includes a second lifting mechanism 422, and the second lifting mechanism 422 is disposed on the second rail mechanism and is movable along the second rail mechanism; the loading assembly 43 includes a second loading needle 432, which second loading needle 432 extends in the height direction of the frame 12 for performing aspiration and loading of reagents.

That is, the sample loading module 40 in this embodiment is provided with the first sample loading needle 431 and the second sample loading needle 432, and the working efficiency of the medical integrated machine in this embodiment can be improved by the action of the two sample loading needles.

The first rail mechanism and the second rail mechanism in the present embodiment are not particularly limited in this application as long as they can move between the detection module 20 and the sample/reagent module 30 by moving the first lift mechanism 421 and the second lift mechanism 422.

The first lifting mechanism 421 and the second lifting mechanism 422 may be a combination of lifting cylinders, sliding rails, pulleys, driving motors, and the like, and are all within the scope of protection of the present application as long as the first loading needle 431 and the second loading needle 432 can be driven to lift.

Further, the medical integrated machine in this embodiment further includes a disc storage module 50 and an loading and unloading module 60. The disk storage module 50 includes a new disk storage bin 51 and a waste disk storage bin 52; the loading and unloading module 60 is disposed on the frame 12 and reciprocates among the PMT detection module 21, the optical method detection module 22, the new disc storage bin 51 and the waste disc storage bin 52 to load and unload the microfluidic disc 70, so as to facilitate the automatic control of the medical integrated machine, and further improve the working efficiency of the medical integrated machine in the embodiment. Further, the loading and unloading module 60 includes a second rail assembly 61, a second lifting assembly 62 and a jaw assembly 63. Wherein the second guide rail assembly 61 is disposed on the frame 12 and above the detection table 11; the second lifting assembly 62 is arranged on the second guide rail assembly 61 and moves along the second guide rail assembly 61; the jaw assembly 63 is disposed at the second elevating assembly 62 for gripping or releasing the microfluidic disc 70. In the specific installation, the second rail assembly 61 may be provided with one rail or two rails, and may be specifically selected according to the actual use requirement, in which fig. 9 in this embodiment shows a case when the second rail assembly 61 is provided with one rail, the rail extends in the left-right direction of the machine body 10, and in the actual operation, the second lifting assembly 62 moves along the rail, so that it may reciprocate above the PMT detection module 21, the optical method detection module 22, the new disc storage bin 51, and the waste disc storage bin 52. The second lifting assembly 62 may include a lifting cylinder, for example, and the jaw assembly 63 may be lifted by the second lifting assembly 62.

The jaw assembly 63 in this embodiment includes a triangular gripper, which includes a first clamping arm, a second clamping arm, and a third clamping arm, and the first clamping arm, the second clamping arm, and the third clamping arm move along a radial direction of the microfluidic disc 70 to grip or put the microfluidic disc 70, so that the microfluidic disc 70 can be stably gripped, and damage to the microfluidic disc 70 is not easy to cause.

To sum up, because the detection bench in this application is provided with a plurality of detection module, and foretell a plurality of detection module can be used for detecting different detection items, that is, medical all-in-one in this application can carry out multi-item detection, and detection efficiency is high, can satisfy medical personnel's different user demands.

Spatially relative terms, such as "above … …," "above … …," "upper surface at … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial location relative to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "above" or "over" other devices or structures would then be oriented "below" or "beneath" the other devices or structures. Thus, the exemplary term "above … …" may include both orientations of "above … …" and "below … …". The device may also be positioned in other different ways (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

In addition, the terms "first", "second", etc. are used to define the components, and are merely for convenience of distinguishing the corresponding components, and unless otherwise stated, the terms have no special meaning, and thus should not be construed as limiting the scope of the present application.

The foregoing is merely a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and variations may be made to the present application by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application should be included in the protection scope of the present application.

Claims

1. A medical all-in-one machine, characterized by comprising:

a machine body (10), wherein the machine body (10) comprises a detection table (11) and a rack (12) arranged above the detection table (11);

the detection modules (20) are multiple, the detection modules (20) are arranged on the detection table (11), and the detection modules (20) are used for detecting different detection items;

a sample/reagent module (30), the sample/reagent module (30) being arranged on the detection stage (11) for placing a sample and a reagent; and

and a sample adding module (40), wherein the sample adding module (40) is arranged on the rack (12) and moves back and forth between the detection module (20) and the sample/reagent module (30) to suck and add samples and reagents.

2. The medical all-in-one machine according to claim 1, wherein the detection module (20) comprises at least a PMT detection module (21) and an optical method detection module (22), wherein,

the PMT detection module (21) is arranged on the detection table (11) and is used for performing immune detection;

the optical method detection module (22) is arranged on the detection table (11) for biochemical and/or coagulation detection.

3. The medical all-in-one machine according to claim 2, wherein the PMT detection module (21) and the optical method detection module (22) are arranged side by side behind the detection stage (11), and the sample/reagent module (30) is arranged in front of the detection stage (11).

4. The medical all-in-one machine according to claim 2, wherein the PMT detection module (21) comprises:

a first mounting frame (211), wherein the first mounting frame (211) is mounted on the detection table (11);

a first tray (212), the first tray (212) being rotatably arranged on the first mounting frame (211), the first tray (212) being used for placing a microfluidic disc (70); and

PMT detection subassembly (213), PMT detection subassembly (213) set up in first mounting bracket (211) and be located the bottom of first tray frame (212), PMT detection subassembly (213) include close light unit (2132) and PMT detection unit (2131), close light unit (2132) liftable set up in PMT detection unit (2131).

5. The medical all-in-one machine according to claim 2, wherein the optical method detection module (22) comprises:

a second mounting bracket (221), wherein the second mounting bracket (221) is mounted on the detection table (11);

a second tray (222), the second tray (222) being rotatably disposed on the second mounting frame (221), the second tray (222) being used for placing a microfluidic disc (70); and

and a light source (223), wherein the light source (223) is arranged on the second mounting frame (221).

6. The medical all-in-one machine according to claim 1, wherein the loading module (40) comprises:

the first guide rail assembly is arranged on the frame (12) and is positioned above the detection table (11);

a first lifting assembly (42), the first lifting assembly (42) being arranged on the first rail assembly and being movable along the first rail assembly; and

and the sample adding component (43) is arranged on the first lifting component (42) so as to absorb and add samples and reagents.

7. The medical all-in-one machine according to claim 6, wherein the first rail assembly comprises a first rail mechanism provided on the frame (12) above the detection table (11);

the first lifting assembly (42) comprises a first lifting mechanism (421), and the first lifting mechanism (421) is arranged on the first guide rail mechanism and can move along the first guide rail mechanism;

the loading assembly (43) comprises a first loading needle (431), and the first loading needle (431) extends along the height direction of the frame (12) so as to puncture the bottle stopper of the sample bottle and suck and fill the sample.

8. The medical all-in-one machine according to claim 6, wherein the first rail assembly further comprises a second rail mechanism provided on the frame (12) above the detection table (11);

the first lifting assembly (42) further comprises a second lifting mechanism (422), and the second lifting mechanism (422) is arranged on the second guide rail mechanism and can move along the second guide rail mechanism;

the loading assembly (43) further comprises a second loading needle (432), the second loading needle (432) extending in the height direction of the frame (12) for performing aspiration and filling of reagents.

9. The medical all-in-one machine according to claim 2, further comprising:

a disk storage module (50), the disk storage module (50) comprising a new disk storage bin (51) and a waste disk storage bin (52); and

and the feeding and discharging module (60) is arranged on the frame (12) and reciprocates between the PMT detection module (21), the optical method detection module (22), the new disc storage bin (51) and the waste disc storage bin (52) to feed and discharge the microfluidic disc (70).

10. The medical all-in-one machine according to claim 9, wherein the loading and unloading module (60) comprises:

a second guide rail assembly (61), wherein the second guide rail assembly (61) is arranged on the frame (12) and is positioned above the detection table (11);

a second lifting assembly (62), the second lifting assembly (62) being arranged on the second guide rail assembly (61) and moving along the second guide rail assembly (61); and

-a jaw assembly (63), the jaw assembly (63) being arranged to the second lifting assembly (62) for gripping or releasing a microfluidic disc (70).