CN116083224A - Liquid taking and culturing automatic device - Google Patents

Liquid taking and culturing automatic device Download PDF

Info

Publication number
CN116083224A
CN116083224A CN202310113358.4A CN202310113358A CN116083224A CN 116083224 A CN116083224 A CN 116083224A CN 202310113358 A CN202310113358 A CN 202310113358A CN 116083224 A CN116083224 A CN 116083224A
Authority
CN
China
Prior art keywords
cotton swab
assembly
space
moving
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202310113358.4A
Other languages
Chinese (zh)
Inventor
郝雨飞
张建华
尚雪松
李辉
刘子丰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Science and Technology Beijing USTB
Original Assignee
University of Science and Technology Beijing USTB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Science and Technology Beijing USTB filed Critical University of Science and Technology Beijing USTB
Priority to CN202310113358.4A priority Critical patent/CN116083224A/en
Publication of CN116083224A publication Critical patent/CN116083224A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/10Petri dish
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/48Holding appliances; Racks; Supports
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/52Mobile; Means for transporting the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/02Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by impregnation, e.g. using swabs or loops
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/20Reduction of greenhouse gas [GHG] emissions in agriculture, e.g. CO2
    • Y02P60/21Dinitrogen oxide [N2O], e.g. using aquaponics, hydroponics or efficiency measures

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Computer Hardware Design (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The application provides a get liquid and cultivate automation equipment, include: the machine seat is provided with a mounting surface; the moving mechanism is arranged on the mounting surface and provided with a moving space and a moving end arranged in the moving space; the moving end can move along the X-axis, Y-axis and Z-axis directions; the cotton swab clamping assembly is arranged at the movable end and used for clamping/releasing cotton swabs; the bearing assembly is mounted on the mounting surface and positioned in the moving space and is used for bearing the sampling bottle; a culturing component which is arranged on the mounting surface and is positioned in the moving space and provided with a culturing space; and the collecting container is arranged on one side of the culture assembly and is provided with a collecting space with an open top. The liquid taking and culturing automatic device is favorable for reducing repeated work of medical staff, improves the inspection work efficiency and reduces the exposure risk of the medical staff.

Description

Liquid taking and culturing automatic device
Technical Field
The application relates to the technical field of body fluid detection, in particular to a liquid taking and culturing automation device.
Background
With the development of society, medical facilities are gradually perfected, people pay attention to health problems of people, medical requirements are continuously rising, clinical laboratories play an extremely important role in hospitals, and accordingly, the pressure of the clinical laboratory in the hospitals is gradually increased, and the number of detection samples is increased along with the expansion of the scale of the hospitals. According to statistics, for a large comprehensive trimethyl-like hospital, the number of patients in each day can reach more than ten thousands, and a clinical laboratory can receive thousands of sample data. The clinical laboratory often needs to cultivate the body fluid sample of gathering in order to carry out follow-up detection, and the microorganism culture flow in laboratory is mainly that the doctor need be repeated utilizes the cotton swab to gather different liquids from various household utensils, then paints in the culture dish, finally puts under different environment and carries out bacterium or germ and cultivates. On one hand, the current full-manual sample culture mode requires repeated labor of medical staff, the repeated labor is extremely easy to cause fatigue of the staff, the efficiency of the staff is obviously reduced in the fatigue working state, and the reduction of the efficiency can influence a clinician to make timely diagnosis and treatment, so that the overall delay is caused; on the other hand, in the process of examination, because of the need of contacting with body fluids such as saliva and urine of patients, if the patients carry viruses, the infection of medical staff is easily caused. Therefore, the application provides an automatic liquid taking and culturing device.
Disclosure of Invention
The purpose of this application is to above problem, provides a get liquid culture automation equipment.
The application provides a get liquid and cultivate automation equipment, include:
the machine seat is provided with a mounting surface;
the moving mechanism is arranged on the mounting surface and provided with a moving space and a moving end arranged in the moving space; the moving end can move along the X-axis, Y-axis and Z-axis directions;
the cotton swab clamping assembly is arranged at the movable end and used for clamping/releasing cotton swabs;
the bearing assembly is mounted on the mounting surface and positioned in the moving space and is used for bearing the sampling bottle;
a culturing component which is arranged on the mounting surface and is positioned in the moving space and provided with a culturing space;
a collection container disposed on one side of the culture assembly, having a collection space with an open top.
According to the technical scheme provided by certain embodiments of the present application, the cotton swab clamping assembly comprises:
a first mounting frame; the first mounting frame is fixedly connected with the mobile end; a first air hole is formed in the first mounting frame;
a first mounting plate; the first mounting plate is mounted on the first mounting frame, and a second air hole is formed in a position corresponding to the first air hole;
the cotton swab clamping piece is made of elastic materials and is internally provided with a clamping space; the side wall of the cotton swab clamping piece is internally provided with an inflation space; the cotton swab clamping piece is also provided with a third air hole communicated with the inflation space; the third air hole is arranged corresponding to the second air hole;
and the inflation assembly is connected with the first air hole and is used for inflating/deflating the inflation space through the first air hole, the second air hole and the third air hole.
According to the technical scheme provided by certain embodiments of the present application, the cotton swab clamping assembly further comprises:
the limiting cover is sleeved outside the cotton swab clamping piece and used for limiting the deformation range of the outer wall of the cotton swab clamping piece when the cotton swab clamping piece is inflated in the inflation space.
According to the technical scheme provided by certain embodiments of the application, the liquid taking and culturing automation device further comprises a horizontal conveying mechanism; the horizontal conveying mechanism is arranged on the mounting surface and is positioned in the moving space; the horizontal conveying mechanism is provided with a conveying end; the conveying end can move along the horizontal direction; the culture assembly is mounted on the delivery end.
According to certain embodiments of the present application, the culture assembly comprises a culture dish and a fixing assembly for fixing the culture dish; the fixing assembly includes:
a fixed housing having an accommodating cavity therein; a strip-shaped opening communicated with the accommodating cavity is formed in one side of the top of the fixed shell; the strip-shaped opening extends along a first direction;
the telescopic driving piece is arranged in the accommodating cavity, and the driving direction of the telescopic driving piece is the first direction;
the fixed clamping piece comprises a fixed piece and a movable piece which are distributed at the top of the fixed shell along the first direction; one end of the movable piece extends from the strip-shaped opening into the accommodating cavity and is fixedly connected with the driving end of the telescopic driving piece.
According to the technical scheme provided by certain embodiments of the application, the liquid taking and culturing automation device further comprises a cotton swab placing component; the cotton swab placing component is arranged in the moving space and is provided with a plurality of cotton swab placing positions.
According to the technical scheme provided by certain embodiments of the present application, the cotton swab placement assembly comprises:
a mounting base; the mounting seat is fixed on the mounting surface;
a second mounting frame; the second mounting frame is mounted on the mounting seat; and a plurality of cotton swab clips are distributed on the second mounting rack.
According to some embodiments of the present application, the second mounting frame is movably connected to the mounting base along the first direction.
According to the technical scheme provided by certain embodiments of the application, the number of the cotton swab placement components is two; the two cotton swab placement components are distributed on two sides of the culture component.
According to the technical scheme provided by certain embodiments of the application, the base is provided with a collecting hole; the collecting container is detachably arranged below the base and corresponds to the collecting hole.
Compared with the prior art, the beneficial effect of this application: the application provides a get liquid culture automation equipment can accomplish and press from both sides and get the cotton swab, dip in liquid sample, paint liquid sample to the culture dish and abandon the whole process of cotton swab, has replaced among the prior art totally artificial sample and has got liquid culture method, is favorable to reducing medical staff's repetitive work, improves the efficiency of inspection work, avoids causing the delay to diagnosis and treatment, is favorable to reducing medical staff's exposure simultaneously, avoids medical staff to infect.
Drawings
FIG. 1 is a schematic diagram of a liquid extraction and culture automation device according to an embodiment of the present disclosure;
FIG. 2 is a schematic side view of an automated liquid extraction culture apparatus according to an embodiment of the present disclosure;
fig. 3 is a schematic structural diagram of a cotton swab clamping assembly of the liquid taking and culturing automation device according to the embodiment of the present application;
FIG. 4 is an exploded view of a swab holder assembly of an automated liquid extraction and culture device according to embodiments of the present application;
fig. 5 is a schematic diagram of an internal structure of a cotton swab clamping assembly of the automatic liquid extraction and culture device according to the embodiment of the present application;
FIG. 6 is a schematic view of a culture assembly of an automated liquid extraction and culture apparatus according to an embodiment of the present disclosure;
fig. 7 is a schematic structural diagram of a cotton swab placement component of the automatic liquid extraction and culture device according to the embodiment of the present application;
FIG. 8 is a schematic side view of a swab placement assembly of an automated liquid extraction and culture device according to embodiments of the present application;
fig. 9 is a schematic structural view of a cotton swab placement module (pulled-out state) of the automatic liquid extraction and culture device according to the embodiment of the present application;
fig. 10 is a schematic structural diagram of a swab holder of an automatic liquid sampling culture device according to an embodiment of the present application.
The text labels in the figures are expressed as:
1. a base; 101. a collection hole;
2. a moving mechanism; 201. a support frame; 202. an X-axis moving assembly; 203. a Y-axis moving assembly; 204. a Z-axis movement assembly;
3. a cotton swab clamping assembly; 301. a first mounting frame; 302. a first mounting plate; 303. a cotton swab holder; 304. a limiting cover; 305. a first air hole; 306. a second air hole; 307. a third air hole;
4. a carrier assembly; 401. a sampling bottle;
5. a culturing assembly; 501. a culture dish; 502. a fixed housing; 503. a telescopic driving member; 504. a fixing member; 505. a movable member;
6. a collection container;
7. a cotton swab placement component; 701. a mounting base; 702. a second mounting frame; 703. a cotton swab holder;
8. a horizontal conveying mechanism.
Detailed Description
In order that those skilled in the art may better understand the technical solutions of the present application, the following detailed description of the present application is provided by way of example and illustration only, and should not be construed to limit the scope of the present application in any way.
It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.
Referring to fig. 1 and 2, the present embodiment provides an automatic liquid-taking and culturing device, which includes:
the device comprises a base 1, wherein the base 1 is provided with a mounting surface;
a moving mechanism 2, the moving mechanism 2 being mounted on the mounting surface and having a moving space and a moving end disposed in the moving space; the moving end can move along the X-axis, Y-axis and Z-axis directions;
the cotton swab clamping assembly 3 is arranged at the moving end and used for clamping/releasing cotton swabs;
a carrying assembly 4, wherein the carrying assembly 4 is installed on the installation surface and is positioned in the moving space, and is used for carrying a sampling bottle 401;
a culturing member 5 mounted on the mounting surface and located in the moving space, the culturing member 5 having a culturing space;
a collection container 6, said collection container 6 being provided on one side of said culture assembly 5, having a collection space open at the top.
Specifically, the base 1 is a plate-shaped structure placed horizontally, the top surface of the base is a mounting surface of the base, a moving mechanism 2 is mounted on the mounting surface of the base, the moving mechanism 2 is a three-axis gantry manipulator, the three-axis gantry manipulator is any one of the prior art, in this embodiment, the three-axis gantry manipulator is mounted on the mounting surface through support frames 201, and the number of the support frames 201 is two; the moving space is formed between the two supporting frames 201; the supporting frame 201 comprises two supporting columns, the two supporting columns are fixed on the mounting surface, and the same supporting plate is mounted on the tops of the two supporting columns; the two support columns and the support plate form an approximate door-shaped structure together; the three-axis gantry manipulator comprises an X-axis moving assembly 202, a Y-axis moving assembly 203 and a Z-axis moving assembly 204; wherein the X-axis moving assembly 202 and the Y-axis moving assembly 203 both extend in a horizontal direction, and the Z-axis moving assembly 204 extends in a vertical direction; for convenience of distinction, the direction in which the support plate extends is referred to as the X-axis direction, the horizontal direction perpendicular to the X-axis direction is referred to as the Y-axis direction, and the vertical direction is referred to as the Z-axis direction; in this embodiment, there are two X-axis moving assemblies 202, the two X-axis moving assemblies 202 are respectively mounted on two support plates and extend along the X-axis direction, the Y-axis moving assembly 203 extends along the Y-axis direction, two ends of the Y-axis moving assembly are respectively fixedly connected with the driving end of the X-axis moving assembly 202, the Z-axis moving assembly 204 extends along the Z-axis direction and is connected with the driving end of the Y-axis moving assembly 203, and the driving end of the Z-axis moving assembly 204 is the moving end; it should be noted that, the structures of the X-axis moving assembly 202, the Y-axis moving assembly 203, and the Z-axis moving assembly 204 are similar, and are all screw-nut transmission mechanisms driven by a servo motor in the prior art, and are not described herein.
When the moving mechanism 2 works, the servo motor of the X-axis moving assembly 202 is started to enable the Y-axis moving assembly 202 to move along the X-axis direction, so that the Z-axis moving assembly 204 is driven to move along the X-axis direction, namely the moving end moves along the X-axis direction; the servo motor of the Y-axis moving assembly 203 is started to enable the Z-axis moving assembly 204 to move along the Y-axis direction, namely the moving end moves along the Y-axis direction; the moving end can be moved in the Z-axis direction by activating the servo motor of the Z-axis moving assembly 204.
Referring to fig. 3 to 5, the cotton swab holding assembly 3 is mounted on the moving end for holding/releasing cotton swabs; the cotton swab holding assembly 3 comprises:
a first mount 301; the first mounting rack 301 is fixedly connected with the mobile end; a first air hole 305 is formed on the first mounting frame 301;
a first mounting plate 302; the first mounting plate 302 is mounted on the first mounting frame 301, and a second air hole 306 is formed at a position corresponding to the first air hole 305;
the cotton swab holder 303 is made of elastic material, and a holding space is formed inside the cotton swab holder 303; the side wall of the cotton swab clamping piece 303 is internally provided with an inflation space; the cotton swab holder 303 is further provided with a third air hole 307 communicated with the air inflation space; the third air hole 307 is disposed corresponding to the second air hole 306;
and an inflation assembly connected to the first air hole 305 for inflating/deflating the inflation space through the first air hole 305, the second air hole 306 and the third air hole 307.
Specifically, the first mounting rack 301 is an L-shaped plate structure, and includes a transverse plate and a vertical plate that are vertically connected, where the vertical plate is fixedly connected to the moving end, and a first air hole 305 is formed in the transverse plate; the first mounting plate 302 is a steel plate, and is mounted on the lower surface of the transverse plate, and is provided with a second air hole 306, wherein the second air hole 306 corresponds to the first air hole 305 in position; the cotton swab clamping piece 303 is made of rubber material, and comprises a circular disc-shaped connecting portion and a cylindrical clamping portion, the outer diameter of the connecting portion is larger than that of the clamping portion, the connecting portion is fixed on the lower surface of the first mounting plate 302, and the clamping portion is located on the lower surface of the connecting portion; a clamping space for clamping the cotton swab is formed inside the clamping part; the side wall of the clamping part is hollow, namely an inflation space is formed, and a third air hole 307 is formed in the connecting part; the third air hole 307 is communicated with the inflation space and corresponds to the position of the second air hole 306; the inflation assembly comprises an air pump and an air pipe connected with an air port of the air pump, and the air pipe is communicated with the first air hole 305.
When the cotton swab clamping assembly 3 works, the air pump is started, air generated by the air pump is filled into the air filling space through the air pipe, the first air hole 305, the second air hole 306 and the third air hole 307, and as the clamping part is made of rubber materials, after the air filling space is filled with air, the clamping part can start to expand, the inner wall of the clamping part expands inwards, so that the clamping space is gradually reduced, the cotton swab can be clamped, when the cotton swab is required to be released, the air in the air filling space is gradually released by controlling the air pump, the clamping part gradually retracts to restore the original state, the clamping space is gradually increased, the cotton swab can be released, and the cotton swab falls from the clamping space.
Further, the cotton swab holding assembly 3 further comprises: the limiting cover 304 is sleeved outside the cotton swab holder 303, and is used for limiting the deformation range of the outer wall of the cotton swab holder 303 when the cotton swab holder is inflated into the inflation space.
Specifically, the limiting cover 304 is made of stainless steel, and comprises a sheet structure located at the upper part, the sheet structure is fixedly connected with the first mounting plate 302, a groove for accommodating the connection part of the cotton swab holder 303 is formed in the top surface of the sheet structure, a limiting sleeve is arranged at the lower part of the sheet structure, and the limiting sleeve is sleeved outside the cotton swab holder 303; through adopting above-mentioned technical scheme, when blowing in to the inflation space, because limit sleeve's limiting displacement, can avoid the outer wall of the clamping part of rubber material to outwards expand to be favorable to making the centre gripping space reduce fast, thereby be favorable to pressing from both sides tightly fast to the cotton swab.
Further, the liquid taking and culturing automation device also comprises a horizontal conveying mechanism 8; the horizontal conveying mechanism 8 is arranged on the mounting surface and is positioned in the moving space; the horizontal conveying mechanism 8 is provided with a conveying end; the conveying end can move along the horizontal direction; the culture assembly 5 is mounted on the delivery end.
Specifically, the horizontal conveying mechanism 8 is a screw nut transmission mechanism driven by a servo motor in the prior art, and is located between the two supporting frames 201, and the moving direction of the conveying end of the horizontal conveying mechanism is the X-axis direction, and when in use, the conveying end can be made to move along the X-axis direction by starting the servo motor of the horizontal conveying mechanism 8, so that the culture assembly 5 is driven to move along the X-axis direction; when the incubation is completed, the incubation assembly 5 may be transported to the end by the horizontal transport mechanism 8, ready for the next process.
Referring to fig. 6, the culture assembly 5 includes a culture dish 501 and a fixing assembly for fixing the culture dish 501; the fixing assembly includes:
a fixed housing 502, wherein the fixed housing 502 is internally provided with a containing cavity; a strip-shaped opening communicated with the accommodating cavity is formed in one side of the top of the fixed shell 502; the strip-shaped opening extends along a first direction;
a telescopic driving part 503, wherein the telescopic driving part 503 is installed in the accommodating cavity, and the driving direction of the telescopic driving part is the first direction;
a fixed clamp including a fixed member 504 and a movable member 505 distributed on top of the fixed housing 502 along the first direction; one end of the movable member 505 extends from the strip-shaped opening into the accommodating cavity, and is fixedly connected with the driving end of the telescopic driving member 503.
Specifically, the fixed housing 502 includes a lower housing fixedly connected with the conveying end and an upper housing butted with the lower housing; the upper shell is provided with a fixed part 504 and a movable part 505, the fixed part 504 is fixedly connected with the upper shell, the movable part 505 movably penetrates through a strip-shaped opening positioned on the upper shell, the length direction of the strip-shaped opening is a first direction, namely the X-axis direction, and a fixed space for fixing the culture dish 501 is formed between the fixed part 504 and the movable part 505; one side of the fixed piece 504 and the movable piece 505, which are close to each other, are respectively provided with a clamping opening which is convenient for clamping the culture dish 501, and the clamping opening is of a V-shaped structure or an arc-shaped structure; a telescopic driving part 503 is installed in a containing cavity formed by the upper shell and the lower shell, the telescopic driving part 503 is a cylinder, the telescopic direction of the cylinder is a first direction, and the free end of a piston rod of the cylinder is connected with the movable part 505.
When the culture assembly 5 is used, the movable piece 505 can be driven to move in a direction relatively far away from the fixed piece 504 by controlling the extension of the piston rod of the air cylinder, the culture dish 501 is placed between the movable piece 505 and the fixed piece 504, and the piston rod of the air cylinder is controlled to retract, so that the movable piece 505 moves in a direction relatively close to the fixed piece 504, and therefore the culture dish is stably fixed from two sides of the culture dish 501. Through adopting above-mentioned technical scheme, be favorable to the centering centre gripping to culture dish 501, can guarantee that culture dish 501 is located the same position on fixed housing 502 when pressing from both sides tightly at every turn.
A bearing component 4 for bearing the sampling bottle 401 is arranged on one side of the horizontal conveying mechanism 8; the bearing assembly 4 comprises a bearing block, a cylindrical bearing hole is formed in the bearing block, and a sampling bottle 401 containing body fluid and in a uncapped state is installed in the bearing hole from top to bottom.
The machine base 1 is further provided with a through collecting hole 101, in this embodiment, two collecting holes 101 are provided, the two collecting holes 101 are respectively located at two sides of the horizontal conveying mechanism 8, and collecting containers 6 are respectively installed at positions corresponding to the two collecting holes 101 below the machine base 1; the collection container 6 is a trash can for collecting used swabs.
Referring to fig. 7 to 9, the automated liquid-taking and culturing device further includes a cotton swab placement component 7; the cotton swab placing component 7 is arranged in the moving space and provided with a plurality of cotton swab placing positions. In this embodiment, the number of the cotton swab placement modules 7 is two; two cotton swab placement modules 7 are distributed on two sides of the culture module 5.
The cotton swab placement assembly 7 comprises a mounting seat 701 and a second mounting frame 702; the mounting seat 701 is fixed on the mounting surface; the second mounting frame 702 is mounted on the mounting seat 701; a plurality of cotton swab clips 703 are distributed on the second mounting rack 702; the second mounting rack 702 comprises two bottom plates and side plates which are perpendicular to each other, two rows of cotton swab clamps 703 are arranged on one side of the side plates, which is relatively close to the horizontal conveying mechanism 8, each row of cotton swab clamps 703 comprises a plurality of cotton swab clamps 703, and the horizontal distance between the cotton swab clamps 703 on the upper row and the horizontal conveying mechanism 8 is greater than the horizontal distance between the cotton swab clamps 703 on the lower row and the horizontal conveying mechanism 8, so that the purpose is to avoid being influenced by the cotton swabs on the upper row when the cotton swabs are clamped and taken down.
Further, the second mounting frame 702 is movably connected to the mounting seat 701 along the first direction; the structure of the mounting seat 701 is a drawer guide rail structure in the prior art, and includes a lower connection portion fixedly connected with the base 1, an upper connection portion fixedly connected with the second mounting frame 702, and an intermediate portion connected between the upper connection portion and the lower connection portion; the connecting part and the lower connecting part are respectively movably connected with the middle part along the X-axis direction.
After the cotton swab on one of the second mounting frames 702 is used up, the second mounting frame 702 can be pulled out from the moving space to be supplemented with a new cotton swab, and during the supplementing period, the cotton swab on the second mounting frame 702 on the other side can be used for liquid taking culture, so that the device can realize continuous liquid taking culture without stopping.
Referring to fig. 10, the swab clamp 703 includes a base, and two groups of clamping jaws disposed on one side of the base, which is relatively close to the horizontal conveying mechanism 8, wherein the two groups of clamping jaws have the same structure and are distributed up and down, each group of clamping jaws includes two clamping jaws, each clamping jaw has a certain elasticity, for example, may be made of PVC material, and each clamping jaw includes a first arc portion, a second arc portion, and a V-shaped portion connected between the first arc portion and the second arc portion; one end of the first arc-shaped part far away from the V-shaped part is connected with the base; the distance between the first arc-shaped parts of the two clamping jaws belonging to the same group is gradually reduced along the direction away from the base, and the distance between the second arc-shaped parts of the two clamping jaws belonging to the same group is gradually increased; the openings of the V-shaped parts of the two clamping jaws belonging to the same group are oppositely arranged, and the two clamping jaws form a space for clamping the cotton swabs together; the cotton swabs are arranged on the two groups of clamping jaws along the vertical direction.
The liquid taking and culturing automation device provided by the embodiment has the working principle that:
(1) The cotton swab clamping assembly 3 is driven to move to any cotton swab placing assembly 7 by the moving mechanism 2, and the inflation assembly is controlled to inflate the inflation space to clamp cotton swabs from the cotton swab placing assembly 7;
(2) The cotton swab clamping assembly 3 is driven to move to the upper side of the bearing assembly 4 through the moving mechanism 2, the cotton swab clamping assembly 3 is controlled to move downwards, and a liquid sample is dipped from the sampling bottle 401 by using a cotton swab;
(3) The cotton swab clamping assembly 3 is driven to move to the position above the culture assembly 5 by the moving mechanism 2, and the cotton swab clamping assembly 3 is controlled to move according to a specified track, so that the cotton swab dipped with the liquid sample is smeared on the culture dish 501;
(4) The cotton swab clamping assembly 3 is driven to move to the position above the collecting hole 101 through the moving mechanism 2, the inflation assembly is controlled to deflate the inflation space to release the cotton swab, and the cotton swab falls into the collecting container 6 below through the collecting hole 101 under the action of self gravity.
Specific examples are set forth herein to illustrate the principles and embodiments of the present application, and the description of the examples above is only intended to assist in understanding the methods of the present application and their core ideas. The foregoing is merely a preferred embodiment of the present application, and it should be noted that, due to the limited nature of text, there is an objectively infinite number of specific structures, and that, to those skilled in the art, several improvements, modifications or changes can be made, and the above technical features can be combined in a suitable manner, without departing from the principles of the present invention; such modifications, variations and combinations, or the direct application of the concepts and aspects of the invention in other applications without modification, are intended to be within the scope of this application.

Claims (10)

1. An automated liquid extraction and culture device, comprising:
the device comprises a base (1), wherein the base (1) is provided with a mounting surface;
a moving mechanism (2), the moving mechanism (2) being mounted on the mounting surface and having a moving space and a moving end disposed in the moving space; the moving end can move along the X-axis, Y-axis and Z-axis directions;
the cotton swab clamping assembly (3) is arranged at the moving end and used for clamping/releasing cotton swabs;
a bearing assembly (4), wherein the bearing assembly (4) is installed on the installation surface and positioned in the moving space, and is used for bearing a sampling bottle (401);
a culturing component (5), wherein the culturing component (5) is arranged on the mounting surface and positioned in the moving space, and has a culturing space;
-a collection container (6), said collection container (6) being arranged on one side of said culture assembly (5) with an open-topped collection space.
2. The automated liquid extraction and culture device according to claim 1, characterized in that the cotton swab holding assembly (3) comprises:
a first mounting frame (301); the first mounting frame (301) is fixedly connected with the mobile end; a first air hole (305) is formed in the first mounting frame (301);
a first mounting plate (302); the first mounting plate (302) is mounted on the first mounting frame (301), and a second air hole (306) is formed in a position corresponding to the first air hole (305);
the cotton swab clamping piece (303), the cotton swab clamping piece (303) is made of elastic materials, and a clamping space is formed in the cotton swab clamping piece; an inflation space is formed in the side wall of the cotton swab clamping piece (303); a third air hole (307) communicated with the inflation space is also formed in the cotton swab clamping piece (303); the third air hole (307) is arranged corresponding to the second air hole (306);
and the inflation assembly is connected with the first air hole (305) and is used for inflating/deflating the inflation space through the first air hole (305), the second air hole (306) and the third air hole (307).
3. The automated liquid extraction and culture device according to claim 2, characterized in that the cotton swab holding assembly (3) further comprises:
the limiting cover (304) is sleeved outside the cotton swab clamping piece (303), and is used for limiting the deformation range of the outer wall of the cotton swab clamping piece (303) when the cotton swab clamping piece is inflated in the inflation space.
4. The automated liquid extraction and culture apparatus of claim 1, further comprising a horizontal transport mechanism (8); the horizontal conveying mechanism (8) is arranged on the mounting surface and is positioned in the moving space; the horizontal conveying mechanism (8) is provided with a conveying end; the conveying end can move along the horizontal direction; the culture assembly (5) is mounted on the delivery end.
5. The automated liquid extraction and culture apparatus of claim 4, wherein the culture assembly (5) comprises a culture dish (501) and a fixing assembly for fixing the culture dish (501); the fixing assembly includes:
a stationary housing (502), the stationary housing (502) having a receiving cavity therein; a strip-shaped opening communicated with the accommodating cavity is formed in one side of the top of the fixed shell (502); the strip-shaped opening extends along a first direction;
a telescopic driving piece (503), wherein the telescopic driving piece (503) is installed in the accommodating cavity, and the driving direction of the telescopic driving piece is the first direction;
a fixed clamp comprising a fixed part (504) and a movable part (505) distributed on top of the fixed housing (502) along the first direction; one end of the movable piece (505) extends into the accommodating cavity from the strip-shaped opening and is fixedly connected with the driving end of the telescopic driving piece (503).
6. The automated liquid extraction and culture apparatus of claim 5, further comprising a cotton swab placement assembly (7); the cotton swab placing component (7) is arranged in the moving space and is provided with a plurality of cotton swab placing positions.
7. The automated liquid extraction and culture apparatus of claim 6, wherein the cotton swab placement assembly (7) comprises:
a mounting base (701); the mounting seat (701) is fixed on the mounting surface;
a second mount (702); the second mounting frame (702) is mounted on the mounting seat (701); and a plurality of cotton swab clips (703) are distributed on the second mounting frame (702).
8. The automated liquid handling culture apparatus of claim 7, wherein the second mounting frame (702) is movably coupled to the mounting block (701) along the first direction.
9. The automated liquid extraction and culture apparatus of claim 6, wherein the number of cotton swab placement modules (7) is two; the two cotton swab placement components (7) are distributed on two sides of the culture component (5).
10. The automated liquid extraction and culture device according to claim 1, wherein the machine base (1) is provided with a collection hole (101); the collecting container (6) is detachably arranged below the base (1) and is arranged corresponding to the collecting hole (101).
CN202310113358.4A 2023-01-28 2023-01-28 Liquid taking and culturing automatic device Pending CN116083224A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310113358.4A CN116083224A (en) 2023-01-28 2023-01-28 Liquid taking and culturing automatic device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202310113358.4A CN116083224A (en) 2023-01-28 2023-01-28 Liquid taking and culturing automatic device

Publications (1)

Publication Number Publication Date
CN116083224A true CN116083224A (en) 2023-05-09

Family

ID=86211894

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202310113358.4A Pending CN116083224A (en) 2023-01-28 2023-01-28 Liquid taking and culturing automatic device

Country Status (1)

Country Link
CN (1) CN116083224A (en)

Similar Documents

Publication Publication Date Title
JP2013033056A (en) Distortive dispensing chip, distortive dispensing apparatus, and method of distortive dispensing processing
CN110270389B (en) Pipetting machine
CN210656954U (en) Full-automatic nucleic acid extraction appearance
CN112808340B (en) Multistation high flux liquid moving equipment
CN111307550A (en) Clinical medicine is smear device for inspection
CN109353807A (en) A kind of rack for test tube automatic conveyor
CN116083224A (en) Liquid taking and culturing automatic device
CN211272507U (en) Inoculating needle sterilizing device
CN216838008U (en) Cell preparation system
EP0253685A1 (en) Liquid handling station
CN210752747U (en) Liquid transfer machine
CN108315243B (en) Automatic sample adding system
CN217878591U (en) Sweeping and trapping device for Vocs sampling in water
CN114525206A (en) Automatic cell preparation device
CN219972290U (en) Device for controlling dip height of inoculating loop in sample tube by utilizing micro weight
CN209493046U (en) A kind of rack for test tube automatic conveyor
CN110508582B (en) Laboratory is with centralized test tube in batches washing drying device
CN210560444U (en) Microorganism detects sampling apparatus
CN209927565U (en) Dip dyeing type dyeing instrument
CN209717562U (en) A kind of syringe apparatus automatization assembling
CN221368319U (en) Blood sampling device for clinical examination for preventing pollution
CN116064223A (en) Device for controlling dip height of inoculating loop in sample tube by utilizing micro weight
CN201906619U (en) Novel medical blood taking test-tube stand
CN219816017U (en) Reagent mixing device
CN214020906U (en) Special support for pipettor

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination