CN116077753A - Plasma separator - Google Patents

Abstract

The embodiment of the application belongs to the technical field of medical instruments, and particularly relates to a plasma separator. The embodiment of the application aims to solve the problem that plasma separated by a related plasma separator is easy to denature. The plasma separator comprises a box body, a centrifugal machine, a plasma output assembly and a cooling device, wherein the centrifugal machine, the plasma output assembly and the cooling device are arranged on the box body, the plasma output assembly comprises a plasma tube and a plasma bag, the centrifugal machine is provided with a liquid inlet end and a liquid outlet end, the liquid inlet end is configured to receive blood from a human body, and the liquid outlet end is communicated with the plasma bag through the plasma tube; the temperature reduction device is configured to reduce temperature of plasma within at least one of the plasma bag and the plasma tube. Through the arrangement, the temperature reducing device reduces the temperature of the plasma in the plasma bag and/or the plasma tube so as to reduce the temperature of the plasma in the plasma tube and the plasma bag, so that the plasma protein is not easy to denature, the coagulation factor is not easy to lose activity, and the quality of the plasma in the plasma bag is improved.

Description

Plasma separator

Technical Field

The embodiment of the application belongs to the technical field of medical instruments, and particularly relates to a plasma separator.

Background

The plasma separator can separate the plasma in the blood and convey the separated plasma to a plasma bag for medical staff.

In the related art, a plasma separator includes a blood pump for pumping blood of a human body and transferring the blood to a centrifuge, and a plasma bag; the centrifuge separates plasma from the blood and delivers the separated plasma to a plasma bag for use by a healthcare worker.

However, due to the high temperature of the plasma separated by the centrifuge, prolonged exposure of the plasma to room temperature conditions can easily result in denaturation of the collected plasma proteins and loss of activity of the unstable clotting factors, thereby affecting the quality of the collected plasma.

Disclosure of Invention

The primary objective of the embodiments of the present application is to provide a plasma separator, so as to solve the problem that the plasma separated by the related plasma separator is easy to denature.

To achieve the above object, embodiments of the present application provide a plasma separator, including a tank, a centrifuge, a plasma output assembly, and a cooling device, the centrifuge, the plasma output assembly, and the cooling device being all disposed in the tank, the plasma output assembly including a plasma tube and a plasma bag, the centrifuge having a liquid inlet end configured to receive blood from a human body and a liquid outlet end communicating with the plasma bag through the plasma tube; the temperature reduction device is configured to reduce temperature of plasma within at least one of the plasma bag and the plasma tube.

In the preferred technical scheme of the plasma separator, the cooling device comprises a semiconductor refrigeration sheet, the semiconductor refrigeration sheet is provided with a cold end and a hot end, the cold end is attached with a cold end heat dissipation plate, and the plasma tube is arranged on one side, far away from the semiconductor refrigeration sheet, of the cold end heat dissipation plate.

In the preferred technical scheme of the plasma separator, a clamping channel is arranged on one side, far away from the semiconductor refrigerating sheet, of the cold end radiating plate, and the plasma tube is clamped in the clamping channel.

In the preferable technical scheme of the plasma separator, the clamping channel extends along a straight line, the cross section of the clamping channel comprises a fitting section, a first limiting section and a second limiting section, and the fitting section is arc-shaped; the first spacing section with the spacing section of second is the straightaway section, the first spacing section with the spacing section of second sets up the relative both ends of laminating section circumference, the spacing section of first keep away from laminating section's one end with the spacing section of second keep away from have the clearance of predetermineeing between the one end of laminating section.

In the preferred technical scheme of the plasma separator, the attaching section is semicircular, and the first limiting section and the second limiting section are tangential to the attaching section.

In the preferred technical scheme of the plasma separator, the plurality of clamping channels are arranged in parallel.

In the preferred technical scheme of the plasma separator, the plasma output assembly further comprises a lifting hook weighing device and a plasma valve, and the plasma bag is hung on the lifting hook weighing device; a plasma valve is disposed in the plasma tube, the plasma valve configured to regulate a flow of plasma within the plasma tube.

In the preferred technical solution of the above-mentioned plasma separator, the plasma separator further includes a blood input assembly, the blood input assembly includes a blood tube, a blood valve and a blood pump, the blood tube is connected to the liquid inlet end of the centrifuge, the blood valve is disposed in the blood tube, the blood valve is configured to regulate the flow rate of blood in the blood tube, and the blood pump is disposed between the blood valve and the centrifuge.

In the preferred technical scheme of the plasma separator, the blood input assembly further comprises a first air detector, a second air detector and a blood pressure detector, wherein the first air detector, the second air detector and the blood pressure detector are all arranged in the blood tube, the first air detector is arranged at one end, far away from the centrifuge, of the blood valve, the blood pressure detector is arranged between the first air detector and the blood valve, and the second air detector is arranged between the blood valve and the blood pump.

In the preferred technical scheme of the plasma separator, the plasma separator further comprises an anticoagulant input assembly, the anticoagulant input assembly comprises an anticoagulant container, an anticoagulant tube, an anticoagulant pump and a third air detector, the anticoagulant container is provided with a liquid outlet, one end of the anticoagulant tube is connected with the liquid outlet, the other end of the anticoagulant tube is communicated with the blood tube, and the anticoagulant pump and the third air detector are both arranged in the anticoagulant tube.

As can be appreciated by those skilled in the art, the plasma separator of the embodiments of the present application includes a tank, a centrifuge, a plasma output assembly, and a cooling device, each of which is disposed in the tank, the plasma output assembly including a plasma tube and a plasma bag, the centrifuge having a liquid inlet end configured to receive blood from a human body and a liquid outlet end in communication with the plasma bag through the plasma tube; the temperature reduction device is configured to reduce temperature of plasma within at least one of the plasma bag and the plasma tube. Through the arrangement, the temperature reducing device reduces the temperature of the plasma in the plasma bag and/or the plasma tube so as to reduce the temperature of the plasma in the plasma tube and the plasma bag, so that the plasma protein is not easy to denature, the coagulation factor is not easy to lose activity, and the quality of the plasma in the plasma bag is improved.

Drawings

Preferred embodiments of the plasma separator according to the embodiments of the present application are described below with reference to the accompanying drawings. The attached drawings are as follows:

FIG. 1 is a schematic diagram of a plasma separator according to an embodiment of the present application;

FIG. 2 is a front view of a plasma separator according to an embodiment of the present application;

FIG. 3 is a top view of a plasma separator according to an embodiment of the present application;

FIG. 4 is a schematic view of the semiconductor refrigeration sheet, cold side heat sink and hot side heat sink in the plasma separator according to the embodiment of the present application;

fig. 5 is a schematic structural view of cold end heat dissipation plate and hot end heat dissipation plate in the plasma separator according to the embodiment of the present application.

In the accompanying drawings:

10. a case;

20. a centrifuge;

310. a plasma bag; 320. a hook weighing device; 330. a plasma valve; 340. a fourth air detector;

410. a semiconductor refrigeration sheet;

420. a cold end heat dissipation plate; 421. a clamping channel; 422. a bonding section; 423. a first limit section; 424. the second limiting section;

430. a hot end heat dissipation plate;

510. a blood valve; 520. a blood pump; 530. a first air detector; 540. a second air detector; 550. a blood pressure detector;

610. an anticoagulant pump; 620. a third air detector;

710. a brine bag; 720. a brine valve;

800. and a control panel.

Detailed Description

First, it should be understood by those skilled in the art that these embodiments are merely for explaining the technical principles of the embodiments of the present application, and are not intended to limit the protection scope of the embodiments of the present application. Those skilled in the art can adapt it as desired to suit a particular application.

Further, it should be noted that, in the description of the embodiments of the present application, terms such as directions or positional relationships indicated by the terms "inner", "outer", and the like are based on the directions or positional relationships shown in the drawings, which are merely for convenience of description, and do not indicate or imply that the apparatus or the member must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the embodiments of the present application.

Furthermore, it should be noted that, in the description of the embodiments of the present application, unless explicitly specified and limited otherwise, the terms "connected," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be the communication between the two components. The specific meaning of the above terms in the embodiments of the present application will be understood by those skilled in the art according to the specific circumstances.

For the purposes of making the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is apparent that the described embodiments are some embodiments of the present application, but not all embodiments. All other embodiments, which can be made by one of ordinary skill in the art based on the embodiments herein without making any inventive effort, are intended to be within the scope of the present application.

Medical staff often use plasma separators to separate plasma from human blood and transport the plasma to plasma bags for use by the medical staff.

The plasma separator in the related art includes a blood pump for pumping blood of a human body and transferring the blood to a centrifuge, and a plasma bag; the centrifuge runs at high speed and separates plasma from the blood, and the separated plasma is conveyed to a plasma bag for use by medical staff.

Because the temperature of the separated blood plasma is higher when the centrifuge is operated at a high speed, and the process of separating the blood plasma from the blood of a human body is longer, the blood plasma is exposed to the room temperature environment for a long time, and the high temperature easily causes the denaturation of the collected blood plasma protein and the inactivation of the unstable coagulation factor, thereby influencing the quality of the collected blood plasma.

The embodiment provides a plasma separator, through the heat sink to the plasma in plasma bag and/or the plasma pipe cooling to reduce the temperature of plasma in plasma pipe and the plasma bag, thereby make the plasma protein be difficult for taking place the denaturation, the coagulation factor is difficult for losing the activity, improved the quality of plasma in the plasma bag.

The principles and features of embodiments of the present application are described below with reference to the drawings, the examples being provided for the purpose of illustrating the embodiments of the present application and not for the purpose of limiting the scope of the embodiments of the present application.

Referring to fig. 1-3, a plasma separator provided in an embodiment of the present application includes a housing 10, a centrifuge 20, a plasma output assembly and a cooling device, wherein the centrifuge 20 and the plasma output assembly are both disposed on the housing 10, the plasma output assembly includes a plasma tube (not shown in the figures) and a plasma bag 310, the centrifuge 20 has a liquid inlet end and a liquid outlet end, the liquid inlet end is configured to receive blood from a human body, the centrifuge 20 operates at a high speed and separates plasma from the blood, and the plasma is discharged from the liquid outlet end.

One end of the plasma tube is communicated with the liquid outlet end, the other end of the plasma tube is communicated with the plasma bag 310, and the plasma tube transmits the plasma at the liquid outlet end into the plasma bag 310.

The temperature reducing device is configured to reduce the temperature of the plasma in at least one of the plasma bag 310 and the plasma tube to reduce the temperature of the plasma in the plasma bag 310, thereby making the plasma protein less likely to be denatured, the coagulation factor less likely to lose activity, and improving the quality of the plasma in the plasma bag 310.

The plasma separator in this embodiment includes a case 10, a centrifuge 20, a plasma output assembly and a cooling device, wherein the centrifuge 20, the plasma output assembly and the cooling device are all disposed on the case 10, the plasma output assembly includes a plasma tube and a plasma bag 310, the centrifuge 20 has a liquid inlet end and a liquid outlet end, the liquid inlet end is configured to receive blood from a human body, and the liquid outlet end is communicated with the plasma bag 310 through the plasma tube; the temperature reduction device is configured to reduce the temperature of plasma within at least one of the plasma bag 310 and the plasma tube. Through the arrangement, the temperature reducing device reduces the temperature of the plasma in the plasma bag 310 and/or the plasma tube so as to reduce the temperature of the plasma in the plasma tube and the plasma bag 310, so that the plasma protein is not easy to denature, the coagulation factor is not easy to lose activity, and the quality of the plasma in the plasma bag 310 is improved.

Referring to fig. 4, in some embodiments, the cooling device includes a semiconductor cooling plate 410, and when direct current passes through a couple formed by connecting two different semiconductor materials in series, heat can be absorbed and released at two ends of the couple, one end of the absorbed heat is a cold end, one end of the released heat is a hot end, and the cold end can achieve the purpose of cooling.

The cold and hot ends may be planar, with the cold end on one side of the semiconductor refrigeration sheet 410 and the hot end on the other side of the semiconductor refrigeration sheet 410. The cold junction can be laminated with cold junction heating panel 420, and the plasma pipe sets up in the one side of keeping away from semiconductor refrigeration piece 410 of cold junction heating panel 420, and the cold junction absorbs the heat of cold junction heating panel 420, makes the temperature of cold junction heating panel 420 reduce, and the plasma pipe sets up in the one side of keeping away from semiconductor refrigeration piece 410 of cold junction heating panel 420, and the plasma of cold junction heating panel 420 in to plasma pipe and plasma pipe is cooled down like this, makes the temperature of plasma pipe and plasma intraductal plasma reduce.

The semiconductor refrigeration piece 410 has small volume, and reduces the occupied space of the plasma separator; second, the semiconductor refrigeration sheet 410 has no moving parts and is also highly reliable.

The hot end may be attached with a hot end heat dissipation plate 430, and the hot end heat dissipation plate 430 may increase the heat exchange area between the hot end and air, so as to improve the heat dissipation efficiency of the hot end.

The box 10 may be provided with a mounting hole, the semiconductor refrigeration sheet 410, the cold end heat dissipation plate 420 and the hot end heat dissipation plate 430 may form an integral body penetrating through the mounting hole, and the cold end heat dissipation plate 420 may be located outside the box 10, and the semiconductor refrigeration sheet 410 and the hot end heat dissipation plate 430 may be both located in the box 10.

Further, a fan may be further disposed in the box 10, and the fan is disposed near the hot end heat dissipation plate 430, so as to accelerate the heat exchange efficiency between the hot end heat dissipation plate 430 and the air in the box 10, thereby improving the heat dissipation efficiency of the hot end.

With continued reference to fig. 4 and 5, in some implementations, a side of the cold side heat sink 420 remote from the semiconductor refrigeration sheet 410 may be provided with a snap-through channel 421, with a plasma tube snap-fit within the snap-through channel 421.

Specifically, the clamping channel 421 may extend along a straight line, and the cross section of the clamping channel 421 may include a fitting section 422, a first limiting section 423 and a second limiting section 424, where the fitting section 422 is in a circular arc shape; the first limiting segment 423 and the second limiting segment 424 are straight-line segments, the first limiting segment 423 and the second limiting segment 424 are arranged at two opposite ends of the circumference of the attaching segment 422, a preset gap is reserved between one end, away from the attaching segment 422, of the first limiting segment 423 and one end, away from the attaching segment 422, of the second limiting segment 424, of the attaching segment 422, the first limiting segment 423 and the second limiting segment 424 are surrounded to form a clamping channel 421, and the plasma tube penetrates through the clamping channel 421 through the preset gap.

The plasma tube is a cylindrical hollow tube, and after the plasma tube passes through the clamping channel 421, the outer side of part of the plasma tube is attached to the attaching section 422. The first limiting section 423 and the second limiting section 424 are used for limiting the degree of freedom of the plasma tube along the radial direction, so that the plasma tube is not easy to slide out of the clamping channel 421, and the clamping channel 421 is more firmly fixed to the plasma tube.

Further, the attaching section 422 may be semicircular, and the first limiting section 423 and the second limiting section 424 may be tangential to the attaching section 422, that is, the first limiting section 423 and the second limiting section 424 are parallel, so that the plasma tube can slide into or out of the clamping channel 421 from the gap between the first limiting section 423 and the second limiting section 424 more easily, which is convenient for the medical staff to clamp the plasma tube into the clamping channel 421 or remove from the clamping channel 421.

Of course, the straight line where the first limiting segment 423 and the second limiting segment 424 are located may further have an included angle, and the gap between the first limiting segment 423 and the second limiting segment 424 gradually decreases along the direction away from the attaching segment 422, so that the plasma tube is not easy to slide out from the gap between the first limiting segment 423 and the second limiting segment 424 after being clamped into the clamping channel 421.

The side of the cold end heat dissipation plate 420 far away from the semiconductor refrigeration sheet 410 may be provided with a plurality of clamping channels 421, and the plurality of clamping channels 421 may be arranged in parallel, so that a medical staff can clamp the plasma tube into the clamping channels 421 more conveniently and rapidly.

The clamping channel 421 may extend along a curve in addition to a straight line, and exemplary, the clamping channel 421 may extend in a spiral shape to reduce an occupied space of the clamping channel 421.

In other possible implementations, the plasma tube may be adhered to the cold-end heat dissipation plate 420 through an adhesive tape, and when the plasma tube needs to be removed from the cold-end heat dissipation plate 420, the adhesive tape is only required to be torn off, which is convenient and fast.

With continued reference to fig. 1, the cold-end heat dissipation plate 420 may be disposed at the outside of the box 10, the plasma bag 310 may also be disposed at the outside of the box 10, and the plasma bag 310 is disposed near the cold-end heat dissipation plate 420, so that the cold-end heat dissipation plate 420 may cool the plasma in the plasma tube, and may cool the plasma in the plasma bag 310, so that the temperature of the plasma in the plasma bag 310 is lower, thereby further avoiding denaturation of plasma proteins and loss of activity of coagulation factors, and improving the quality of the plasma in the plasma bag 310.

In other embodiments, the cooling device may include a compressor, a condenser, a throttling element, and an evaporator, which are sequentially connected in series by a pipeline, in which a refrigerant circulates, and the plasma bag 310 and a portion of the plasma tube are disposed adjacent to the evaporator.

The compressor compresses the low-temperature low-pressure gaseous refrigerant into a high-temperature high-pressure gaseous refrigerant, the high-temperature high-pressure gaseous refrigerant is conveyed to the condenser, the high-temperature high-pressure gaseous refrigerant is cooled and depressurized into a low-temperature low-pressure liquid refrigerant after radiating, the low-temperature high-pressure liquid refrigerant flows through the throttling element, the low-temperature low-pressure liquid refrigerant exchanges heat with the plasma tube when flowing through the evaporator, the low-temperature low-pressure liquid refrigerant absorbs heat of plasma in the plasma tube and is gasified into a low-temperature low-pressure gaseous refrigerant, and a large amount of heat is absorbed by gasification, so that the temperature of the plasma in the plasma bag 310 and the plasma tube is lowered.

In some possible embodiments, the cooling device may further include a refrigeration box disposed outside the case 10, and the refrigeration box is covered outside the plasma bag 310.

In the implementation manner that the cooling device includes the semiconductor cooling fin 410, the cold end of the semiconductor cooling fin 410 or the cold end heat dissipation plate 420 is disposed in the cooling box body, so that the temperature in the cooling box body is reduced, and the temperature of the plasma bag 310 and the plasma in the plasma bag 310 are reduced.

In an implementation where the cooling device includes a compressor, a condenser, a throttling element, and an evaporator, the evaporator may be disposed in the refrigeration cassette, and the evaporator may absorb heat in the refrigeration cassette, so that the temperature in the refrigeration cassette is reduced, and further the plasma bag 310 and the plasma in the plasma bag 310 are reduced.

With continued reference to fig. 1, in some embodiments, the plasma output assembly may further include a hook scale 320 and a plasma valve 330, the plasma bag 310 being hooked to the hook scale 320, the hook scale 320 weighing the plasma bag 310 to obtain a target weight of plasma; the plasma valve 330 is disposed in the plasma tube, the plasma valve 330 being configured to regulate the flow of plasma within the plasma tube.

The hook scale 320 may be manually observed and when the weight of the plasma bag 310 reaches the target weight, the plasma valve 330 is manually adjusted so that plasma no longer flows to the plasma bag 310.

Further, the plasma separator may further include a main controller, and the hook scaler 320 and the plasma valve 330 may be electrically connected to the main controller, and the main controller may be configured to close the plasma valve 330 when the weight of the plasma weighed by the hook scaler 320 reaches a target weight.

The plasma output assembly may also include a fourth air detector 340, the fourth air detector 340 being disposed on the plasma tube between the centrifuge 20 and the plasma valve 330 to detect the air content in the plasma discharged by the centrifuge 20.

In some embodiments, the plasma separator may further include a blood input assembly including a blood tube connected to the liquid inlet end of the centrifuge 20, a blood valve 510 disposed on the blood tube, the blood valve 510 configured to regulate the flow of blood within the blood tube, and a blood pump 520 disposed between the blood valve 510 and the centrifuge 20.

The end of the blood tube far away from the centrifuge 20 can be communicated with the blood vessel of the human body through the disposable syringe needle, the blood pump 520 can continuously input the blood of the human body into the centrifuge 20, the blood valve 510 is used for regulating the flow of the blood in the blood tube, when the blood is required to be extracted from the human body, the blood valve 510 is opened, and when the blood is not required to be extracted from the human body, the blood valve 510 is closed.

In some embodiments, the blood input assembly may further include a first air detector 530, a second air detector 540, and a blood pressure detector 550, where the first air detector 530, the second air detector 540, and the blood pressure detector 550 are all disposed on the blood tube, and the first air detector 530 is disposed on an end of the blood valve 510 away from the centrifuge 20 to detect the air content in the blood tube at the front end of the blood valve 510.

The blood pressure monitor 550 is disposed between the first air detector 530 and the blood valve 510, and the blood pressure monitor 550 has an exhaust branch pipe through which air in blood flowing through the blood pressure monitor 550 can be exhausted.

A second air detector 540 is disposed between the blood valve 510 and the blood pump 520 to detect the air content in the blood tube between the blood valve 510 and the blood pump 520.

Further, the number of the first air detectors 530 may be plural, and the plurality of the first air detectors 530 are sequentially connected in series with the blood tube, so that the air content in the blood tube detected by the first air detectors 530 is more accurate.

In some embodiments, the plasma separator may further include an anticoagulant input assembly including an anticoagulant container for containing an anticoagulant, the anticoagulant container having a liquid outlet, an anticoagulant pump 610 and a third air detector 620, one end of the anticoagulant tube being connected to the liquid outlet, the other end of the anticoagulant tube being in communication with the blood tube to deliver the anticoagulant from the anticoagulant container to the blood tube, the anticoagulant may prevent blood from clotting.

An anticoagulant pump 610 and a third air detector 620 are both provided to the anticoagulant tube, the anticoagulant pump 610 allowing the anticoagulant to be continuously delivered from the anticoagulant holder to the blood tube. The third air detector 620 may detect the air content within the anticoagulant tube.

Further, the anticoagulant tube may be connected to the blood tube at the front end of the first air detector 530, or the anticoagulant tube may be connected to the end of the blood tube far from the centrifuge 20, so that the blood from the human body can be quickly mixed with the anticoagulant after flowing into the blood tube, thereby effectively preventing the blood in the blood tube from being coagulated.

The anticoagulant input assembly may further include an electronic scale configured to weigh the anticoagulant flowing from the anticoagulant container to the anticoagulant tube to balance the amount of anticoagulant flowing into the blood tube with the amount of blood in the blood tube, so that, on one hand, excessive anticoagulant flowing into the blood tube may be avoided to cause anticoagulant waste, and on the other hand, insufficient anticoagulant flowing into the blood tube may be avoided to cause blood coagulation.

In some embodiments, the plasma separator may further include a saline input assembly, which may include a saline bag 710, a saline tube connected between the saline bag 710 and the plasma tube, and a saline valve 720 to transfer saline within the saline bag 710 into the plasma tube.

The plasma separator may include a blood drawing process in which blood flows in the direction of a human body, a blood tube, the centrifuge 20, a plasma tube, and a plasma bag 310, and a blood transfusion process.

In the blood transfusion process, the flowing direction of blood is a plasma tube, a centrifuge 20, a blood tube, a human body. After the plasma is collected in the plasma bag 310, the whole blood from which the plasma has been separated in the centrifuge 20 is mixed with physiological saline and then transferred to the human body.

The acquisition of the target weight of plasma requires multiple blood drawing-transfusion procedures to avoid damage to the human body from one drawing of excessive blood.

The plasma separator may further include a control panel 800, and the rotational speed of the centrifuge 20, the target weight of plasma, etc. are set by the control panel 800.

In summary, the plasma separator according to the embodiment of the present application includes a case 10, a centrifuge 20, a plasma output assembly and a cooling device, wherein the centrifuge 20, the plasma output assembly and the cooling device are all disposed on the case 10, the plasma output assembly includes a plasma tube and a plasma bag 310, the centrifuge 20 has a liquid inlet end and a liquid outlet end, the liquid inlet end is configured to receive blood from a human body, and the liquid outlet end is communicated with the plasma bag 310 through the plasma tube; the temperature reduction device is configured to reduce the temperature of plasma within at least one of the plasma bag 310 and the plasma tube. Through the arrangement, the temperature reducing device reduces the temperature of the plasma in the plasma bag 310 and/or the plasma tube so as to reduce the temperature of the plasma in the plasma tube and the plasma bag 310, so that the plasma protein is not easy to denature, the coagulation factor is not easy to lose activity, and the quality of the plasma in the plasma bag 310 is improved.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present application, and not for limiting the same; although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present application.

Claims (10)

1. A plasma separator comprising a housing, a centrifuge, a plasma output assembly and a temperature reduction device, the centrifuge, the plasma output assembly and the temperature reduction device being disposed in the housing, the plasma output assembly comprising a plasma tube and a plasma bag, the centrifuge having a liquid inlet end configured to receive blood from a human body and a liquid outlet end in communication with the plasma bag through the plasma tube;

the temperature reduction device is configured to reduce temperature of plasma within at least one of the plasma bag and the plasma tube.

2. The plasma separator of claim 1, wherein the cooling device comprises a semiconductor refrigeration sheet having a cold end and a hot end, the cold end being bonded with a cold end heat sink, the plasma tube being disposed on a side of the cold end heat sink remote from the semiconductor refrigeration sheet.

3. The plasma separator according to claim 2, wherein a side of the cold end heat dissipation plate away from the semiconductor refrigeration sheet is provided with a clamping channel, and the plasma tube is clamped in the clamping channel.

4. The plasma separator of claim 3, wherein the clamping channel extends along a straight line, the cross section of the clamping channel comprises a fitting section, a first limiting section and a second limiting section, and the fitting section is circular arc-shaped;

the first spacing section with the spacing section of second is the straightaway section, the first spacing section with the spacing section of second sets up the relative both ends of laminating section circumference, the spacing section of first keep away from laminating section's one end with the spacing section of second keep away from have the clearance of predetermineeing between the one end of laminating section.

5. The plasma separator of claim 4, wherein the conforming section is semi-circular and the first and second spacing sections are both tangential to the conforming section.

6. The plasma separator of claim 4, wherein the plurality of clamping channels are arranged in parallel.

7. The plasma separator of any one of claims 1 to 6, wherein the plasma output assembly further comprises a hook scale and a plasma valve, the plasma bag being hooked to the hook scale;

the plasma valve is disposed in the plasma tube, the plasma valve configured to regulate a flow of plasma within the plasma tube.

8. The plasma separator of any one of claims 1 to 6, further comprising a blood input assembly including a blood tube connected to the inlet end of the centrifuge, a blood valve disposed in the blood tube, and a blood pump disposed between the blood valve and the centrifuge, the blood valve configured to regulate the flow of blood within the blood tube.

9. The plasma separator of claim 8, wherein the blood input assembly further comprises a first air detector, a second air detector, and a blood pressure detector, the first air detector, the second air detector, and the blood pressure detector are all disposed in the blood tube, and the first air detector is disposed at an end of the blood valve distal from the centrifuge, the blood pressure detector is disposed between the first air detector and the blood valve, and the second air detector is disposed between the blood valve and the blood pump.

10. The plasma separator of claim 8, further comprising an anticoagulant input assembly including an anticoagulant container having a liquid outlet, an anticoagulant tube having one end connected to the liquid outlet, an anticoagulant pump and a third air detector, the other end of the anticoagulant tube in communication with the blood tube, the anticoagulant pump and the third air detector both disposed in the anticoagulant tube.

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