CN116075365A - 微流控基板、微流控芯片及微流控系统 - Google Patents
微流控基板、微流控芯片及微流控系统 Download PDFInfo
- Publication number
- CN116075365A CN116075365A CN202180002431.XA CN202180002431A CN116075365A CN 116075365 A CN116075365 A CN 116075365A CN 202180002431 A CN202180002431 A CN 202180002431A CN 116075365 A CN116075365 A CN 116075365A
- Authority
- CN
- China
- Prior art keywords
- electrode
- steering
- straight
- sub
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000758 substrate Substances 0.000 title claims abstract description 95
- 239000007788 liquid Substances 0.000 claims description 88
- 210000001624 hip Anatomy 0.000 claims description 39
- 230000002209 hydrophobic effect Effects 0.000 claims description 15
- 238000003860 storage Methods 0.000 claims description 12
- 229910052751 metal Inorganic materials 0.000 claims description 5
- 239000002184 metal Substances 0.000 claims description 5
- 230000005484 gravity Effects 0.000 claims description 3
- 238000000034 method Methods 0.000 description 19
- 230000008569 process Effects 0.000 description 17
- 238000013461 design Methods 0.000 description 13
- 238000010586 diagram Methods 0.000 description 13
- 238000010276 construction Methods 0.000 description 7
- 238000005516 engineering process Methods 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 5
- 230000007704 transition Effects 0.000 description 5
- 238000012938 design process Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 238000009736 wetting Methods 0.000 description 4
- 238000011161 development Methods 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- 230000010354 integration Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000005452 bending Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 229920002313 fluoropolymer Polymers 0.000 description 2
- 239000004811 fluoropolymer Substances 0.000 description 2
- -1 polydimethylsiloxane Polymers 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 229910052581 Si3N4 Inorganic materials 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000003851 biochemical process Effects 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000010353 genetic engineering Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- AMGQUBHHOARCQH-UHFFFAOYSA-N indium;oxotin Chemical compound [In].[Sn]=O AMGQUBHHOARCQH-UHFFFAOYSA-N 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 229920002120 photoresistant polymer Polymers 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920000052 poly(p-xylylene) Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 description 1
- 238000004528 spin coating Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000007740 vapor deposition Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
- B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0427—Electrowetting
Abstract
Description
PCT国内申请,说明书已公开。
Claims (35)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2021/116325 WO2023028968A1 (zh) | 2021-09-02 | 2021-09-02 | 微流控基板、微流控芯片及微流控系统 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN116075365A true CN116075365A (zh) | 2023-05-05 |
Family
ID=85410741
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202180002431.XA Pending CN116075365A (zh) | 2021-09-02 | 2021-09-02 | 微流控基板、微流控芯片及微流控系统 |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP4349485A1 (zh) |
CN (1) | CN116075365A (zh) |
WO (1) | WO2023028968A1 (zh) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9808800B2 (en) * | 2015-04-10 | 2017-11-07 | Unversity Of Macau | Electrode-voltage waveform for droplet-velocity and chip-lifetime improvements of digital microfluidic systems |
CN108970658B (zh) * | 2018-07-27 | 2020-03-06 | 京东方科技集团股份有限公司 | 一种有源矩阵数字微流控芯片 |
CN109174219B (zh) * | 2018-10-15 | 2021-12-24 | 京东方科技集团股份有限公司 | 微流控基板及其驱动方法和微流控装置 |
CN109718874B (zh) * | 2018-12-22 | 2021-03-19 | 北京工业大学 | 一种分离影响液滴内部流动行为变量的微流控芯片 |
-
2021
- 2021-09-02 CN CN202180002431.XA patent/CN116075365A/zh active Pending
- 2021-09-02 WO PCT/CN2021/116325 patent/WO2023028968A1/zh active Application Filing
- 2021-09-02 EP EP21955506.7A patent/EP4349485A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2023028968A1 (zh) | 2023-03-09 |
EP4349485A1 (en) | 2024-04-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10022719B2 (en) | Droplet manipulation device | |
US11169109B2 (en) | Electrochemical detection chip and detection method thereof | |
US8147668B2 (en) | Apparatus for manipulating droplets | |
BRPI0607213B1 (pt) | aparelho para manipulação de gotículas em uma placa de circuito impresso | |
EP1487581A1 (en) | Microfluidic channel network device | |
JP2003222633A (ja) | マイクロチップ | |
CN110665554B (zh) | 基于聚合物复合薄膜快速制备双层dmf芯片及制备方法 | |
US20190329259A1 (en) | Digital microfluidic devices | |
CN116075365A (zh) | 微流控基板、微流控芯片及微流控系统 | |
TWI444324B (zh) | 液體介電泳裝置 | |
JP4660492B2 (ja) | 交流電気泳動法による微細流体の混合・移送装置及び微細流体の混合・移送方法 | |
EP4112176A1 (en) | Microfluidics chip | |
CA2500252C (en) | Methods and apparatus for manipulating droplets by electrowetting-based techniques | |
EP4151312A1 (en) | Microfluidic substrate, and microfluidic apparatus and driving method therefor | |
US20220088600A1 (en) | Devices and methods for fluid actuation | |
WO2022084821A1 (en) | Particle-sorting fluidic device and methods for using thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication |