CN116033922A - 特异性识别肺炎克雷伯菌o1抗原的抗体及其应用 - Google Patents

特异性识别肺炎克雷伯菌o1抗原的抗体及其应用 Download PDF

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Publication number
CN116033922A
CN116033922A CN202280003347.4A CN202280003347A CN116033922A CN 116033922 A CN116033922 A CN 116033922A CN 202280003347 A CN202280003347 A CN 202280003347A CN 116033922 A CN116033922 A CN 116033922A
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China
Prior art keywords
amino acid
acid sequence
sequence seq
antibody
antigen
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Pending
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CN202280003347.4A
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English (en)
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牛玉强
晏丽
李忠
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Beijing Solobio Genetechnology Co Ltd
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Beijing Solobio Genetechnology Co Ltd
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Publication of CN116033922A publication Critical patent/CN116033922A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

本申请涉及特异性识别肺炎克雷伯菌O1抗原的抗体或抗原结合片段,及其制备方法和用途。

Description

PCT国内申请,说明书已公开。

Claims (18)

  1. PCT国内申请,权利要求书已公开。
CN202280003347.4A 2021-08-25 2022-08-24 特异性识别肺炎克雷伯菌o1抗原的抗体及其应用 Pending CN116033922A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2021109802722 2021-08-25
CN202110980272 2021-08-25
PCT/CN2022/114384 WO2023025173A1 (zh) 2021-08-25 2022-08-24 特异性识别肺炎克雷伯菌o1抗原的抗体及其应用

Publications (1)

Publication Number Publication Date
CN116033922A true CN116033922A (zh) 2023-04-28

Family

ID=85321559

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280003347.4A Pending CN116033922A (zh) 2021-08-25 2022-08-24 特异性识别肺炎克雷伯菌o1抗原的抗体及其应用

Country Status (2)

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CN (1) CN116033922A (zh)
WO (1) WO2023025173A1 (zh)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2021131224A (ru) * 2015-02-17 2021-11-03 Х4 Фармасьютикалз (Австрия) ГмбХ Антитела, нацеленные на о-антиген на основе галактана из k. pneumoniae
EP3362474A1 (en) * 2015-10-16 2018-08-22 ARSANIS Biosciences GmbH Bactericidal monoclonal antibody targeting klebsiella pneumoniae
CA3003356A1 (en) * 2015-10-28 2017-05-04 Arsanis Biosciences Gmbh Antibodies targeting a mannan-based o-antigen of k. pneumoniae
JP7160484B2 (ja) * 2016-10-19 2022-10-25 メディミューン,エルエルシー 抗o1抗体およびその使用

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Publication number Publication date
WO2023025173A1 (zh) 2023-03-02

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